LOCUS       NZ_AP024139            29020 bp    DNA     circular CON 23-MAR-2024
DEFINITION  Aeromonas caviae strain KAM329 plasmid pKAM329_3, complete sequence.
ACCESSION   NZ_AP024139
VERSION     NZ_AP024139.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00254948
            Assembly: GCF_015508545.1
KEYWORDS    RefSeq.
SOURCE      Aeromonas caviae
  ORGANISM  Aeromonas caviae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1
  AUTHORS   Suzuki,M., Maehana,S. and Kitasato,H.
  TITLE     Whole genome sequencing of carbapenem-resistant Aeromonas spp.
            isolated in Japan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29020)
  AUTHORS   Suzuki,M., Maehana,S. and Kitasato,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) Contact:Masato Suzuki National Institute of
            Infectious Diseases; 4-2-1 Aobacho, Higashimurayama, Tokyo 189-0002,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler v. 0.4.8.0; Canu v. 1.8
            Genome Coverage                   :: 192x
            Sequencing Technology             :: Illumina MiniSeq; ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015508545.1-RS_2024_03_23
            Annotation Date                   :: 03/23/2024 01:47:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,922
            CDSs (total)                      :: 4,764
            Genes (coding)                    :: 4,613
            CDSs (with protein)               :: 4,613
            Genes (RNA)                       :: 158
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 122
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 38 of 151
            Pseudo Genes (incomplete)         :: 115 of 151
            Pseudo Genes (internal stop)      :: 22 of 151
            Pseudo Genes (multiple problems)  :: 20 of 151
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024139.1.
            Annotated at DFAST https://dfast.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..29020
                     /organism="Aeromonas caviae"
                     /mol_type="genomic DNA"
                     /strain="KAM329"
                     /db_xref="taxon:648"
                     /plasmid="pKAM329_3"
                     /geo_loc_name="Japan:Kanagawa"
                     /collection_date="2018"
     gene            join(28941..29020,1..199)
                     /locus_tag="JN439_RS24225"
     CDS             join(28941..29020,1..199)
                     /locus_tag="JN439_RS24225"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202211495.1"
                     /translation="MSGDDKQLELEALAAVGEMLLFDQARGNPEEAARILRCARLFARS
                     EDAAQRLSELCNEAGSDATWRENIVEELQDREDLQAAEAAMEARRQA"
                     /name="hypothetical protein"
     gene            479..727
                     /locus_tag="JN439_RS24230"
                     /old_locus_tag="KAM329_47560"
     CDS             479..727
                     /locus_tag="JN439_RS24230"
                     /old_locus_tag="KAM329_47560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family toxin"
                     /protein_id="WP_012585400.1"
                     /translation="MQSSIERTVSGVRCTNDDLKPVLVALATDQPLDVRYRDHDLSGDW
                     AGYRECHIKPDLLLIYRKSDADTLRLARLGSHSELFG"
                     /name="type II toxin-antitoxin system YafQ family toxin"
     gene            854..1429
                     /locus_tag="JN439_RS24235"
                     /old_locus_tag="KAM329_47570"
     CDS             854..1429
                     /locus_tag="JN439_RS24235"
                     /old_locus_tag="KAM329_47570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009602860.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001173919.1"
                     /translation="MALIGYARVSTAEQDTALQTDALRNAGCERVFEDTASGAKADRPG
                     LADALAYLRDGDVLVVWRLDRLGRSLPHLIETVGKLEARGVGFRSLTENIDTTTPGGRL
                     IFHVFGALGQFERDLIRERTKAGLTAAAARGRKGGRKPVVTADKLQRARELVANGLNVR
                     EAAARLKVGKTALYAALQAASSGSAADS"
                     /name="recombinase family protein"
     gene            <1495..1812
                     /locus_tag="JN439_RS24240"
                     /old_locus_tag="KAM329_47580"
                     /pseudo=""
     CDS             <1495..1812
                     /locus_tag="JN439_RS24240"
                     /old_locus_tag="KAM329_47580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013721910.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /name="integrase"
     gene            <1876..2298
                     /locus_tag="JN439_RS24245"
                     /old_locus_tag="KAM329_47590"
                     /pseudo=""
     CDS             <1876..2298
                     /locus_tag="JN439_RS24245"
                     /old_locus_tag="KAM329_47590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984345.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /name="hydrolase"
     gene            complement(2305..3321)
                     /locus_tag="JN439_RS24250"
                     /old_locus_tag="KAM329_47600"
     CDS             complement(2305..3321)
                     /locus_tag="JN439_RS24250"
                     /old_locus_tag="KAM329_47600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_202212045.1"
                     /translation="MKIKFSSAKEQQPTQEQGLQVLYAPGKRLAFRVRWYLILLAVLSP
                     LLWLIGRWVLTLWLIEAPAQLHLPGSELRARDAAQVQQLLVQPGQRVTAGELLVRLDNS
                     EWRARRFLLEAASTPMESPNAASLAAERALLQESLAGAEARVRQVQRLLDAGAATRGEL
                     LAATDLRDVRLRELYQLEQRRQPDAGPEQRQRDLELAWLDSRLQGLELRAENDGRVGEI
                     LVAPGENVGPGTPLLRVESDGEAQVWVYLDPRHAAEATPGKLLTLIFPDHSQRQAVVIQ
                     AVDDAAPVPVELRPPFSAPTRRLRVIARVHDGLPPEWRIDRLGLKARFPHRWLPFGG"
                     /name="HlyD family efflux transporter periplasmic adaptor
                     subunit"
     gene            complement(3331..5415)
                     /locus_tag="JN439_RS24255"
                     /old_locus_tag="KAM329_47610"
     CDS             complement(3331..5415)
                     /locus_tag="JN439_RS24255"
                     /old_locus_tag="KAM329_47610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003286296.1"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="WP_202212046.1"
                     /translation="MRRVFLLLGLLGLASSCLAEVLPLPALLDGANSTPLLRAAEAEGA
                     ALEALQRQREAEAGWQWFASAGIGRYRELVTEEVRDDYYGRDLALGLRHPLLGSLKRQQ
                     DALRSVEDQRQQQQARLQLARLEQRLALRSAYADWWRAQEELRWCDGIAEPARRAREQL
                     AARLREGWLLASEARLQDGRWQALERRCAAAGPLLEETRYSLQSLSGQTIEPQSQAQTE
                     ALAASAQPLSAWLQQLERHPRLQERRGQLRQAERNRQSPWYAAVDLSFSVAQSYEDRSG
                     GNEPGNGLVASISLSAPFDPLSYGQARGDEGAARHQMALAQLDAERERLVQGLGQALRA
                     QRAAAEDLLQARQQLEAAALAVREQRLRRAGDVDQAYLGSLAAELEHGYAGLRLIAAWH
                     GLWLREAALRLFVDDDVAHAPLLGPATLDWQAPVAAAHTAAAPRAVQWQQGVYLWDSHA
                     LLDEQRRAEALAQLRAAGMQRLYLGLDAAQVAEPERLRGQLRVLLSAAREQGFEVLLLL
                     GDPHWLQPEGRQGLLDLLGELTTLPFAGLHLDLEVEQLGWPVPEARLRDWMDTLTAAAS
                     VSPWPLELSSHHRWFAAPRAGEYCVPCELRQRGVRQVSLMIYTRNAARSAELAADIARR
                     WPGLSFRLAQSVEPQLAADESWSAASRAQLQAQTERWRQQLQPQAVAGIDWQDWSHYPH
                     "
                     /name="TolC family protein"
     gene            complement(5415..6743)
                     /locus_tag="JN439_RS24260"
                     /old_locus_tag="KAM329_47620"
     CDS             complement(5415..6743)
                     /locus_tag="JN439_RS24260"
                     /old_locus_tag="KAM329_47620"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003286298.1"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="WP_202212047.1"
                     /translation="MEGFWLQWLGILGEIDKPDGLGYLLVMLFPAFLLLEVPLSLVILL
                     GVLRWFVRKPFELPEGNSYQPRVSCVITCYSEGRDVQTTLLSLCEQTYRGEIEMIPVVD
                     GATANHATMQAVRDFRLDAQLYPRRFLRPIAKWQRGGRVSSLNAGLEYSTGEIVMALDG
                     DTSFDNDMVVNVVRHFQDPDVPAVAGSLRVRNARASLTTAMQALEYLLSIQLAKIGLSE
                     WNVVNNVSGAFGAFRRSFLQKIGGWDTHTAEDLDITLRIKNYFGRRPLRIPFEPRAIGH
                     TDAPVTFRQFLMQRLRWDGDLFFLYVRKHRHSFTPRLLGWPNFLVVLVSGFFFQLVLPF
                     IILGYFIVGLYSLTLSTFLVLAWLVYLVYLANTLLAYVVAVCMVSERPRQDLWLCWVVP
                     LFPLFMFVMRCWSAVAILNEMIRRGHEETSMAPWWVLRKAKRF"
                     /name="glycosyltransferase"
     gene            complement(6745..8127)
                     /locus_tag="JN439_RS24265"
                     /old_locus_tag="KAM329_47630"
     CDS             complement(6745..8127)
                     /locus_tag="JN439_RS24265"
                     /old_locus_tag="KAM329_47630"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_202212048.1"
                     /translation="MPRVAVLGASSSPVVGIEYERHPEWSALAALPAYDIVLLDLPAVR
                     AGEALRSLRMDKRYRFSLIYCCQEQDASCKALSDGAPPADLSALVPLWRLWQERFALFN
                     RGVAPERFESRVLAWLWLHPHGAIHAVRDAGVAQHYHYPLLEALEDDESPNAFAWLQLM
                     TQQGWLEEGELVDRVRLCVGCGSGRLNYVDVCPECQTLEIARQPSLHCFTCGHVGAQEH
                     FLKDGLLLCPNCFSRLRHIGSDYDRPLENYRCRSCQAFFVDAEVEARCLDCGQAHAPDK
                     LRVREVRHFRLAEAGRLRCRQGYSASVAETDQFGALNLLNQKSFHELLNWQLQLVRRYK
                     QPAFSLLGLRFVNLAATISALGELRGHALVDSLVERLQEAVRDTDRCSRVSEEILWIMM
                     PHTDAAGLAVVRKRLQEGAERLASEQIGQLQLRQIGFTAPADLLEQEDAALLLARLNGE
                     LG"
                     /name="diguanylate cyclase"
     gene            8528..8767
                     /locus_tag="JN439_RS24270"
                     /old_locus_tag="KAM329_47640"
     CDS             8528..8767
                     /locus_tag="JN439_RS24270"
                     /old_locus_tag="KAM329_47640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005740683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_042044878.1"
                     /translation="MSVMSVRLPDEVEQQLGQLAQSTGRTKSWLANQAIKDYLAREAWQ
                     ITEVEAALREADAGDFVSEKEMMAKFNRWGINAG"
                     /name="CopG family ribbon-helix-helix protein"
     gene            8757..9041
                     /locus_tag="JN439_RS24275"
                     /old_locus_tag="KAM329_47650"
     CDS             8757..9041
                     /locus_tag="JN439_RS24275"
                     /old_locus_tag="KAM329_47650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017411299.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_139731036.1"
                     /translation="MQVKWLRKAALNLEDAHDYLAKENPRVAQEFAHEVYRLVNLLVEQ
                     PSMGRSGRVPGTRELVVQPYPFLIPYRVKGEEIHILRVFHTRLRLPSHW"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            9341..9970
                     /gene="parA"
                     /locus_tag="JN439_RS24280"
                     /old_locus_tag="KAM329_47660"
     CDS             9341..9970
                     /gene="parA"
                     /locus_tag="JN439_RS24280"
                     /old_locus_tag="KAM329_47660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017411316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="WP_202212049.1"
                     /translation="MLVISVLNQKGGSGKTTIATHLARAFQVAGRDVLLIDSDPQGSAR
                     DWSAVRDEQPVPVVGIDRPTIERDIKAVSHKDLIVIDGAPQAADLAISAIKASNLVLIP
                     VQPSPYDIWAASDLVDLVKQRIEMTDGRLKAAFVVSRAIKNTKIGAEIREALEGYGLPV
                     LAARVTQSVAYPSTAAAGTTVLDAEPNSNAAQEIRDLADEVLELLK"
                     /name="parA"
     gene            9991..10188
                     /locus_tag="JN439_RS24285"
                     /old_locus_tag="KAM329_47670"
     CDS             9991..10188
                     /locus_tag="JN439_RS24285"
                     /old_locus_tag="KAM329_47670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005918372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_139731038.1"
                     /translation="MSVLKAGRPSSEKRAMTMGDIAGSVKMKRVNFDLPEALHTKLKMH
                     AAAQGKSIKDIMTDFVEALP"
                     /name="plasmid partition protein ParG"
     gene            complement(11149..12726)
                     /locus_tag="JN439_RS24290"
     CDS             complement(11149..12726)
                     /locus_tag="JN439_RS24290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing methyl-accepting chemotaxis
                     protein"
                     /protein_id="WP_001323889.1"
                     /translation="MRQNLPVTGRNLELPKDANILSTTSPQSHITYVNPDFIKISGFTE
                     EELLGQPHNIVRHPDMPPAAFEHMWSTLKSGRSWMGLVKNRCKNGDHYWVSAYVTPIAK
                     NGSIVEYQSVRTKPEPEQVLAAEKLYAQLRSGKAARPKLAASFSVKILLLIWGSIISSA
                     MAAGMLTDTSISSLLLATLMSGSLSSVSVLAILSPLGRLVERARNISNNPLSQSLYTGR
                     TDEFGQIEFALRMMQAETGAIVGRIGDASNRLSEHTRGLLKDIESSNVLTVEQQAETDQ
                     IATAVNQMVASIQEVASNAQHAADAAGRADTETASGQRLVAHTSQSITALEGEIRQATQ
                     VIHELEGQSNEISKVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAA
                     RTQQSTTDIQSMISALQERAQSAVTVMEQSSRQAHTSVAHAEEAATALDGIGQRVNEIT
                     DMNAQIATAVEQQGAVSEDINRSIINIRDAADTNVQTGQNNLQSAKSVAQLTSALSELA
                     KQFWEKRG"
                     /name="PAS domain-containing methyl-accepting chemotaxis
                     protein"
     gene            13466..14503
                     /locus_tag="JN439_RS24295"
                     /old_locus_tag="KAM329_47710"
     CDS             13466..14503
                     /locus_tag="JN439_RS24295"
                     /old_locus_tag="KAM329_47710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200161.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_182934362.1"
                     /translation="MTSVAKLIDRQDDIANGVAAPLGLPKFDTYAICNLRGGIGKTSLA
                     FNLSYYTDDLLVLDTCPQGNLSYFFDNNFLSSNSLSVNDLLMPYFVPGLGFATRVAKKI
                     SATNNFFASKNSYFIPSSSDLYILPTQIANALAQARLIAGPNQVSIIDNMLFSLKKEIS
                     REWGETETSKCLIDTSPFFSGATHLSWHAADALIVPVRTDQQSINSLELLLDTLSNPAS
                     EFRRVMPSNQHTPKIQMVVLTHCGWSTVPGAKNKPNNQTKVYLEKVRDIVSRNITHFTT
                     QDPDNHILLLDDFLGCGRMSSARSKPIELLNPGESMTINRVKATVNPSVMKIRQELKFI
                     SQNIW"
                     /name="ParA family protein"
     gene            complement(15014..15256)
                     /locus_tag="JN439_RS24300"
                     /old_locus_tag="KAM329_47720"
     CDS             complement(15014..15256)
                     /locus_tag="JN439_RS24300"
                     /old_locus_tag="KAM329_47720"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_104456124.1"
                     /translation="MAKKLINLDDLGAGAPLKEVVTATDGSRGKIPTKAKNIQNMPLEF
                     FTRHAALREKGNTSLLFTAYIIEAVRKALEDDEQR"
                     /name="hypothetical protein"
     gene            complement(15291..15935)
                     /locus_tag="JN439_RS24305"
                     /old_locus_tag="KAM329_47730"
     CDS             complement(15291..15935)
                     /locus_tag="JN439_RS24305"
                     /old_locus_tag="KAM329_47730"
                     /inference="COORDINATES: protein motif:HMM:NF018691.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_104456142.1"
                     /translation="MIVAVAHNKGGVGKTTTVVQLAGELKPEIIIDLDAHQGIAIINGR
                     RPAELRWDVRANLDKAALIKLLKAVGEHLVLIDCGGFDSELVRIAIAAADLIIAPSNDD
                     ITEQIGLVRFNRVLSEISQATGEPIQAHVLMTRTNPSRKNFAAISDELTRLPHLTMMTS
                     KLSRRADWANQMESGLGVTERAATRSSAAGMEAKALAEEVRSKLAMLTKQY"
                     /name="ParA family protein"
     gene            complement(16594..16836)
                     /locus_tag="JN439_RS24310"
                     /old_locus_tag="KAM329_47740"
     CDS             complement(16594..16836)
                     /locus_tag="JN439_RS24310"
                     /old_locus_tag="KAM329_47740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein RepB"
                     /protein_id="WP_202211498.1"
                     /translation="MEELQAKWTFDQGGFAKALIVPTPMGQGYHLHLVKFGKQSETIFL
                     ERQRGGWRVFKSIDAAANTANGIGFRRIEIDLSSR"
                     /name="plasmid replication protein RepB"
     gene            complement(17172..18143)
                     /locus_tag="JN439_RS24315"
                     /old_locus_tag="KAM329_47750"
     CDS             complement(17172..18143)
                     /locus_tag="JN439_RS24315"
                     /old_locus_tag="KAM329_47750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="WP_202211497.1"
                     /translation="MARCDRAHPNARNFGLGSRDMGYAGLNALREGMQSHSSIATMADR
                     WSQFAAWAREAAGIRDMRQIVTDTLRGYADHLLTRLEQGEISPATAQNALSAVNRVLEI
                     ARGDRLVRLDPVHEAGLPIRSGIATTDRAVSLSQHDHAVATVSERVAAILSLQRAFGLR
                     FEEAAKLDAVRALAQAQHGMVRIEVGTKGGLARDVPITNPLEQKFLLANAANIQENARS
                     LIPAHQTYREFRAEAYAELRSAGIRSHGERHAYAQERYAALVGAPAPVAAGVAHGAAHH
                     RFLAVRLGLTVAAARALDQQARERVAAELGHGRLDVTNTYLG"
                     /name="integrase domain-containing protein"
     gene            18343..18567
                     /locus_tag="JN439_RS24320"
                     /old_locus_tag="KAM329_47760"
     CDS             18343..18567
                     /locus_tag="JN439_RS24320"
                     /old_locus_tag="KAM329_47760"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202211496.1"
                     /translation="MVRLRLASGWPVSDDFVGFRAWESWRHGPRALEWRRVGAGRLCLT
                     ETAGGYRRITVASAIRAIEAEAEQHNHFG"
                     /name="hypothetical protein"
     gene            <18918..>19432
                     /locus_tag="JN439_RS24325"
                     /old_locus_tag="KAM329_47770"
                     /pseudo=""
     CDS             <18918..>19432
                     /locus_tag="JN439_RS24325"
                     /old_locus_tag="KAM329_47770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002804302.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            19719..19967
                     /locus_tag="JN439_RS24330"
                     /old_locus_tag="KAM329_47780"
     CDS             19719..19967
                     /locus_tag="JN439_RS24330"
                     /old_locus_tag="KAM329_47780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008168813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142875131.1"
                     /translation="MTVQETLDRLGLYWKRDPDFVPVKDKATVRLNVSIGGGGVELLAT
                     GPKWYDTRAEQGGGGAIDLTMHLFRLPFVDAVKRLSP"
                     /name="hypothetical protein"
     gene            20510..21421
                     /locus_tag="JN439_RS24335"
                     /old_locus_tag="KAM329_47790"
     CDS             20510..21421
                     /locus_tag="JN439_RS24335"
                     /old_locus_tag="KAM329_47790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005796449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="WP_202212044.1"
                     /translation="MARQGITFEQVAAVADALAGEGQQPTIRAVREKLGDTGSPNTIHK
                     HLTAWREARPVAAAAAPELPQALTAAIAAEIERAASRARGEIEGRLVQAQAEAAELAAA
                     GEVLEGERDELAEQVAVLTTERDTLAGKAAQQATDLAEAQQRIEREQQAAESARLEVAT
                     ARHKIEAQAERVSEQAAELERLRAALAEAQQGRTAAEQQAAVLAAKLEACADRVSRAEA
                     RAEQIEQQAAKAAQAHDTARAAAAQETRQTQAERDEARKVAAEAREQAARLAGQLEALQ
                     RQQDKAEAAEKATKAPKGKGGE"
                     /name="DNA-binding protein"
     gene            21807..22634
                     /locus_tag="JN439_RS24340"
                     /old_locus_tag="KAM329_47810"
     CDS             21807..22634
                     /locus_tag="JN439_RS24340"
                     /old_locus_tag="KAM329_47810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020308987.1"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="WP_059385974.1"
                     /translation="MPKTRKHLTPTEAEAKGLLCRKHLKERLRLMPGLNTKPAGSVWQG
                     QGAYDVYNPAECVPWRWMPGRAQVRRQHVAAQAKDLIAAGCIVLDTETTGLGDDAEICE
                     ITILDVTGAPILDTLVRPTRPIPVEATAIHKITDAMVASAPSWPEVAEQYAAAVAGRTV
                     VAYNVAFDARLLRQTYQIHGLTAPVLTTACAMLMYAEWHGEYDRSRDRWRWLKLIEAAT
                     DCGVAEDGAHRALADARMTLGVLRYLQRRTNGRRPAGPKVATVPQEALPSVLG"
                     /name="3'-5' exonuclease"
     gene            complement(22788..23381)
                     /locus_tag="JN439_RS24345"
                     /old_locus_tag="KAM329_47820"
     CDS             complement(22788..23381)
                     /locus_tag="JN439_RS24345"
                     /old_locus_tag="KAM329_47820"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="OfxX fusion product"
                     /protein_id="WP_223930628.1"
                     /translation="MRIKIKGEITAERLAEALHAAAEKYEAVRPGHKVYGANLYLTAFD
                     ADGLPFDLVDHRGEPLSITIEAKSGELVKPALTAEGEARRQKAKEEARRQAEEAEAEAQ
                     RRHRQTLDEYEQERQKRRKKEAEARKQFEDANAITAELLKTMPERFIDELNKTVQGVWG
                     DLKPTETQGKKKGQPKALPVFSVHADGLLLSVET"
                     /name="OfxX fusion product"
     gene            complement(23378..24016)
                     /locus_tag="JN439_RS24350"
                     /old_locus_tag="KAM329_47830"
     CDS             complement(23378..24016)
                     /locus_tag="JN439_RS24350"
                     /old_locus_tag="KAM329_47830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6753 family protein"
                     /protein_id="WP_009873359.1"
                     /translation="MSDLDDSFAKLLGRQPSDAERQSLYRVRDALGLKNNDALWLVLMA
                     LQHYQGQYEKFPQAIAQAAKDTLVNFKVTADATVKASAEAAKADLAQAVAAAAQEVAHN
                     TSAKQMWQWAAGCIAVAFLCVGLFGWYMHSSGKDSGYQAGYGAGYTEAKDEKAAAAWAN
                     TPEGRLAYRFAQTGSLASLAKCDRPGWYVEKGVCYVKPASDGTYGWRLP"
                     /name="DUF6753 family protein"
     gene            complement(24009..24692)
                     /locus_tag="JN439_RS24355"
                     /old_locus_tag="KAM329_47840"
     CDS             complement(24009..24692)
                     /locus_tag="JN439_RS24355"
                     /old_locus_tag="KAM329_47840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="WP_015060218.1"
                     /translation="MAKSIYLIGGSKGGVGKSLVTMATVDYLQERGESVLLIESDTSNP
                     DVWKAYKESTETELINLDEADGWIQLVNLCDSKPDSVVVINTAARNNKGVSAYGETLNS
                     TLEELKRKLVTLWVINRQRDSLELLKEYMDAIPNADVHVVRNGHFGEENKFELYNGSKL
                     RTAVEERGGKSVTFPDMADRVSDDIYSKRMSIAVALKELPIGNRAELTRWRNEAKKVLE
                     AVVHE"
                     /name="mobilization protein"
     gene            complement(24705..25061)
                     /locus_tag="JN439_RS24360"
                     /old_locus_tag="KAM329_47850"
     CDS             complement(24705..25061)
                     /locus_tag="JN439_RS24360"
                     /old_locus_tag="KAM329_47850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015060219.1"
                     /translation="MKCTTEQLEAIAAKLREMPPVEKKKQEHSKQDAVRILSKEIALLQ
                     KRGYTLDQISETLRGEGLSIATPTLKSYLQRAKPAKKAPVQAPGDTPRPRPAVKKPADT
                     SKATFTPKPDSDDI"
                     /name="hypothetical protein"
     gene            25371..25691
                     /locus_tag="JN439_RS24365"
                     /old_locus_tag="KAM329_47860"
     CDS             25371..25691
                     /locus_tag="JN439_RS24365"
                     /old_locus_tag="KAM329_47860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003869.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_021029055.1"
                     /translation="MPFETQGPEPLDAVINVRLTAAEKARLKEDADLAGLSMSELVRRR
                     YFGRPIIANADAVMLKELRRIGGLLKHIHNESGGIYNKDTAGALVALKAYIGKLSRDRQ
                     EG"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            25672..28344
                     /gene="traI"
                     /locus_tag="JN439_RS24370"
                     /old_locus_tag="KAM329_47870"
     CDS             25672..28344
                     /gene="traI"
                     /locus_tag="JN439_RS24370"
                     /old_locus_tag="KAM329_47870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI/MobA(P) family conjugative relaxase"
                     /protein_id="WP_059385972.1"
                     /translation="MIVKKVKNPQKAASKAVRVSRLTDYIREPERENSQEKCIHAGARG
                     FITDEPQSQTAEMIALSQEAVRSKDTINHYVLSWREGEQPSPEQVEEAVSIFMDELGVK
                     DHQAIYGLHADTDNLHLHLAINRVHPETLKVVKINNGFDIEAAHKAIARIENAQGWQRE
                     QNGRYQVLENGELGREHIDKDKPRQPAQPKRDMENRTGEKSAERIAIEDGAPIIKKAQT
                     WEQLHRELAAKGMRYEKTGSGATLFVGDVGVKASSADRDASLSKLQKRLGAYQPPPQRQ
                     QVAQREPEPIKPDVPGWKDYITGRKAHYAEKNAAKLALDKRQEQERKQIAEQQKARRDE
                     LMRGNWKGKGEVLNAMRSVIAAEQAAEKAALKEKHQKQREQHRQQFRPYPDLEQWQRMQ
                     KSPELAEQWRHRASEPQRIEGASGEPPTPRDIRAYQPEIVGQQVHYSRKEEAGAGGGVS
                     FVDKGKSIDIHDWRNRDSTLAALQLSAQKWGSFTVTGNDEYKAMCAKLAAEHGFKITNP
                     ELQERIQQERQRIQQERAQAMKSEQLKQFELYAEAVGAERYRVTSIKMQADGRKQTFIL
                     DKKDGITRGFTPQEIEQRTPEMLRLQRRGENLYYTPLSDKKHHILIDDMNREKLERLIR
                     DGYRPAVVLESSPGNYQAIITVPKLGTAHDKDVGNRLSDALNREYGDPKLSGAIHPHRA
                     PGYENRKPKHQREDGSYPEVRLLKAERRECVKALALSSQIDAEYQRQAALKAQQPERSK
                     AKPALELAAASGSAIDAYQRHYRDVIKRQRGGEVDLSRVDSMIAVRMRVTGHDQAAIEG
                     AIRQCAPATRQKGEGRDWNDYAQRTARYAYSAAGDRQAAELGKYRQQWEKLEGREPVRQ
                     QEQAKAQKIERDNSPGMSR"
                     /name="traI"
     gene            28386..28664
                     /locus_tag="JN439_RS24375"
                     /old_locus_tag="KAM329_47880"
     CDS             28386..28664
                     /locus_tag="JN439_RS24375"
                     /old_locus_tag="KAM329_47880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_015060221.1"
                     /translation="MELEWDADKAARNLKKHGVSFEDAELVFYDSGRVEAYDGREDYGE
                     DRWATIGLAYSAVLYVVYTVRHEETIRLISARKANADERKQYREANS"
                     /name="BrnT family toxin"
     gene            28624..28944
                     /locus_tag="JN439_RS24380"
                     /old_locus_tag="KAM329_47890"
     CDS             28624..28944
                     /locus_tag="JN439_RS24380"
                     /old_locus_tag="KAM329_47890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_045286807.1"
                     /translation="MPTKESNIVKRTLDLKKPPQLSAEQKARLDAVASMPDEQIDYSDA
                     PYLPDAVWMKAAEQLPHTKKQITLRIDAEVLEFFKHTGKRYQSRMNAVLRSYVEAHKAH
                     AK"
                     /name="BrnA antitoxin family protein"
     Typing          complement(16608..16770)
                     /name="rep_cluster_2037"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.634"
                     /coverage="87.0"
                     /evalue="8.2e-52"
     Typing          25673..28338
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.676"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 caacccggaa gaagccgccc gcatcctgcg atgtgcgcgg ctttttgctc gttcagagga
       61 tgccgcgcag cgtctcagcg agctatgcaa cgaggcgggc agtgatgcga cttggcgcga
      121 aaacatcgtg gaggaactgc aagaccgaga ggacttgcaa gccgccgagg cagcgatgga
      181 agcccgccga caggcctaac ttgttgcgca agcggatagt gccgacacgg ccttgcagac
      241 cctaatggac gaggtagcgg cggacacctt cggcagtctc gatgaaggat atgcggcaca
      301 ggcgcaggcc gaggccgtga aggcgtggca gggcaggcag tgagcggcat ttgttggtgt
      361 ttcatcgtaa cccggcaagt gttcagcaaa cggtggtttg ttggacagtt gccgcaaggg
      421 gcagtttttg tcattttcag aagacgactg caccagacaa cgcggtttga aggcagttgt
      481 gcagtcgtct attgaacgaa cagtatcagg agtccgctgc acgaatgatg acctcaagcc
      541 ggttctggtc gcgctggcga ccgatcagcc cctggatgtg cgataccgcg accacgatct
      601 ttccggcgat tgggcgggct accgcgaatg ccacatcaag cccgacctgc tgctgatcta
      661 ccgcaagtcc gacgccgaca ccctgcgact ggcgcggctt ggctcccata gcgagctgtt
      721 cggctgatgc cagtcgcctt gtccgccaaa cgatcattag gcggccaaac cggacgcctg
      781 tccgaaaaca tcttgcgcaa cgggatgacg gacaataaga taggcggacg gtataacgga
      841 caaatgggcg gaaatggcac tcatcggcta tgcgcgggta tcgacggcgg aacaggacac
      901 cgccttgcag acggatgcgc tgcgcaatgc aggctgcgaa cgggttttcg aggacacggc
      961 atccggggcc aaggcagacc ggcccggctt ggccgatgcg ctggcttatc tgcgcgatgg
     1021 cgatgtgctg gtcgtctggc ggctggatcg gcttggccgc tccctgccgc acctgattga
     1081 gacggtcggc aagctggaag cacggggcgt cggcttccgc tcgttgactg aaaacatcga
     1141 caccaccacg ccgggcggac ggctcatctt ccatgtgttc ggtgcgctgg gccagttcga
     1201 gcgcgacctg atccgcgagc gcaccaaggc cgggttgacc gctgccgccg cacgcgggcg
     1261 caaaggcgga cgcaagccgg ttgtcactgc cgacaagttg caacgagcgc gggagcttgt
     1321 cgccaacggc ttgaatgtcc gcgaggccgc cgcacgcctc aaggtaggaa aaaccgctct
     1381 ctacgctgcc ttgcaggcgg ccagttctgg cagtgcagcc gactcctgat atttcgtgca
     1441 gtcgccttct gaaaacgaca atcaggcaaa aatgcgtcgc catcaggcga gacaggcaag
     1501 tcccgcaggt ggatcagcta cgagatcaag gcgggcaact tgctggcgtt gaacgtgggc
     1561 aaccgcggcc agcgggtgcc ggactggcac ctcgacccac tcaagcacga gctgatccag
     1621 tccgtcctca agctgaccag gggtgcggac ccttggcaga tctaccatgc actgctgcag
     1681 ccgcgctcga tgctgcgggg gcgttcggca ctggagggcg tgacggccag caatctcgac
     1741 aagctcgtca tggcagtgag cacagccgtg aaggaaagcg aatggacccc gccgcgagtc
     1801 ggggtcgcct agcagcagga atgcgggatc gtggcgaaac cgcgattccc gcgcgtctgt
     1861 caggacacca ggcgcgcgca tttcatgaag gcgatggtgg cctacgtgag ggacaaacag
     1921 cagcgcttcc agcgcgaggg gctgctgaac cacctcggtg ccttgcagag cctcggcccg
     1981 ctgcacggca tgcgcacctt ctgggatttc gacggtcgct tcaccgcacc gctgcacggc
     2041 tacagcgacg cccaggacta ctaccgccgt gcctccagcc gctactacct gccagagatc
     2101 acgacaccaa ccctgctgat ccaggccgcg gacgacccct tcgtgtttcg ccacagcgtg
     2161 ccggaaccaa ccgaactgtc ggcgaccaca accctggagc tgcaccgccg cggcggccac
     2221 gtcggctttg tcgaaggcac accgcgccgc ccgcgttact acctggatcg gcgcattccg
     2281 cagtggctgg cgggctgaga cgtttcagcc gccaaatggc aaccatcggt gcgggaagcg
     2341 cgccttgaga ccgagccggt caatgcgcca ctcaggcggc agaccatcgt gcacccgcgc
     2401 aatcacgcgc agcctgcgtg tcggcgcact gaacggtggg cgcagttcga ccggcaccgg
     2461 cgcggcatcg tccaccgcct gaatcactac cgcctggcgt tgactatggt cgggaaagat
     2521 cagcgtcagc agctttccgg gtgtggcctc ggcagcgtgg cgcggatcga gataaaccca
     2581 gacctgcgcc tcgccgtcgc tctcgacgcg caacaggggc gtgcccggcc cgacgttctc
     2641 gccaggcgcg acgaggattt cgccgacgcg gccatcgttc tcggcgcgca gttccagccc
     2701 ctgcaaacgg ctgtccagcc aggccagctc cagatcgcgc tggcgctgtt cgggtccggc
     2761 atccggctgg cgccgctgct ccagctgata cagttcgcgc agccgtacat cacgcagatc
     2821 ggtcgccgcc agcaactcgc cacgggttgc cgcgccggca tcgagcagcc gctggacctg
     2881 ccgtacgcgc gcttcggcac ccgccagcga ctcctgcagc agcgcccgtt cggctgccag
     2941 gctggcggca ttcgggcttt ccatcggcgt gctcgccgcc tccagcagga agcgccgcgc
     3001 acgccattcc gagttgtcca gacgtaccag cagctcgccg gccgtgaccc gctgccccgg
     3061 ctgtaccagc agctgctgga cctgcgcggc gtcacgggcg cgcagctcgc tgcccggcag
     3121 atgcagctga gccggcgcct cgatcagcca cagcgtgagc acccagcggc cgatcagcca
     3181 aagcagcgga ctgagtaccg ccagcagaat gaggtaccag cgcactcgaa aggccaggcg
     3241 cttgcccggc gcatagagca cctgcaggcc ctgctcctgg gtgggttgtt gctccttggc
     3301 gctggagaat ttgatcttca tgcaatgtgc tcaatgggga tagtgagacc agtcctgcca
     3361 gtcgatgccg gcaacggcct gtggctgcaa ctgctggcgc cagcgctcgg tctgcgcctg
     3421 caattgcgcg cgcgaggcgg cgctccagct ttcatccgcc gccagctgcg gctccacgct
     3481 ctgcgccagg cggaacgaca gtcccggcca gcggcgcgca atatccgccg ccagctccgc
     3541 actgcgtgcg gcgttgcggg tgtagatcat caggctgacc tggcgcacgc cgcgctggcg
     3601 cagctcgcag gggacgcagt attcgccggc gcgcggtgcg gcgaaccagc ggtgatggct
     3661 ggacagctca agcggccagg gactgacgct cgcggccgcc gtcagcgtat ccatccagtc
     3721 gcgcagccgc gcctcgggga ccggccagcc gagctgctcg acttccagat ccagatgcag
     3781 accggcgaac ggcagcgtcg tcagctcacc gagcagatcg agcaacccct gacgaccctc
     3841 gggttgtagc cagtgcggat cgccgagcag cagcagcacc tcgaatccct gttcgcgcgc
     3901 ggcactgagc aacacgcgca actggccgcg caagcgctcc ggctcagcca cttgggcggc
     3961 gtccaggccg aggtagagac gctgcatgcc ggccgcgcgc agttgcgcca atgcctcggc
     4021 gcggcgctgt tcgtcgagca gtgcgtggct gtcccagaga tagacgccct gttgccattg
     4081 caccgcccgg ggagccgccg ccgtgtgtgc ggccgccacc ggtgcctgcc agtcgagcgt
     4141 ggccggcccg agcaacggcg cgtgcgcaac atcgtcgtcc acgaacaggc gcagagccgc
     4201 ttcccgcagc cacaacccgt gccaggcggc gatcaggcgc agcccggcgt agccgtgctc
     4261 cagctcggcc gccaggctgc ccagataggc ctgatcgacg tcgccagcgc gccgcagacg
     4321 ctgctcacgc acggccagcg ccgccgcttc caactgctgg cgcgcctgca gcaggtcttc
     4381 ggcggccgcg cgctgcgcac gcagtgcctg gccgaggccc tgcaccaggc gctcacgctc
     4441 ggcatcgagc tgcgccagcg ccatctggtg acgcgccgcg ccctcatcac cgcgcgcctg
     4501 cccgtaggac agcgggtcga agggcgccga caggctgatg ctggccacca gcccattgcc
     4561 cggctcgttg ccaccgctgc ggtcttcgta gctctgcgcg acgctgaagc tcaaatcgac
     4621 cgccgcgtac cacggactct gccgattgcg ctcggcctga cgcagctggc cgcgccgctc
     4681 ctgcagacgt ggatgccgct cgagctgctg caaccaggcg ctcagaggct gcgcgcttgc
     4741 cgccagtgct tcggtctggg cctggctttg cggctcgatg gtctgtccac tcagcgactg
     4801 caggctgtag cgggtttctt ccagcagcgg cccggcggcg gcgcaacggc gctccagcgc
     4861 ctgccagcgg ccatcctgca gacgcgcctc ggaagccagc aaccagcctt cgcgcaggcg
     4921 cgccgccagc tgctcgcgcg cgcgccgtgc aggctcggcg atgccgtcgc accagcgcag
     4981 ttcttcctgc gctcgccacc agtcggcata ggcgctgcgc agtgccaggc gctgctcgag
     5041 gcgcgccagc tgcagtcgcg cctgctgttg ctggcgctgg tcttcgacgc tgcgcaacgc
     5101 atcctgctgg cgcttcaggc tgcccagcag tggatgacgc aagccgagcg ccagatcgcg
     5161 accgtagtag tcgtcgcgca cctcttcggt caccagctcc cgatagcgcc cgatccctgc
     5221 cgaggcgaac cattgccagc cggcttcggc ctcgcgctgg cgctgcaatg cctcgagcgc
     5281 cgcaccttcg gcctcggccg cgcgcagcag cggcgtgctg ttggcgccat cgagcagcgc
     5341 cggtagcggc aatacctcgg ccagacagga tgaagccagt cccagcagac ccagcaatag
     5401 gaatactcgc cgcatcagaa cctcttcgcc ttgcgcagca cccaccaggg cgccatcgag
     5461 gtttcctcat ggccacgccg gatcatttcg ttgaggatcg ccactgcgct ccagcagcgc
     5521 atgacgaaca tgaacagcgg aaacagcggc accacccagc acagccacag gtcctgccgc
     5581 ggccgctcgg acaccatgca caccgctacc acgtaggcca gcagggtgtt ggccaagtac
     5641 accagataga ccagccaggc gagcaccagg aaggtcgaca gcgtcagcga gtacagtccg
     5701 acgatgaagt agccgaggat gatgaacggc agcaccagct ggaagaagaa cccgctgacc
     5761 agcaccacca gaaagttcgg ccagccgagc aggcgcggcg tgaaactgtg gcgatgcttg
     5821 cgcacataga ggaagaacag atcgccatcc cagcgcaggc gctgcatgag gaactggcgg
     5881 aacgtcaccg gcgcgtcggt atggccgatg gcgcggggct cgaacggaat gcgcagcggc
     5941 cggcggccga agtagttctt gatgcgcagg gtgatatcca gatcctcggc ggtatgggta
     6001 tcccagccac cgattttctg cagaaagctg cgacgaaagg cgccgaacgc gccggatacg
     6061 ttattcacca cgttccactc gctgagcccg atcttggcca gctggatcga cagcaggtat
     6121 tccagcgcct gcatcgccgt ggtcagcgag gcgcgagcgt tgcgcacccg caggctgccc
     6181 gccaccgccg gcacgtccgg gtcctggaaa tggcgcacca cgttgaccac catgtcgttg
     6241 tcgaacgagg tatcgccatc cagcgccatg acgatctcac cggtgctgta ttccagccca
     6301 gcgttcagtg aggacacccg tccgccacgc tgccacttgg cgatcggccg cagaaagcgc
     6361 cgcggataca actgcgcatc gaggcgaaaa tcccgcacgg cctgcatcgt cgcgtgattg
     6421 gccgtcgcgc cgtcgaccac cggaatcatc tcgatctcgc cgcgataggt ctgctcgcac
     6481 aggctgagca gcgtggtctg cacatcccga ccttcgctat agcaggtgat cacgcaggac
     6541 acgcgcggct ggtaactgtt gccttccggc agctcgaagg gtttgcgcac gaaccagcgc
     6601 agcacgccga gcaggatcac caggctgagc ggcacctcca gcaacagaaa cgccggaaac
     6661 agcatcacca gcagatagcc caggccgtcg ggcttgtcga tttcgccgag aatccccagc
     6721 cactgcagcc agaaaccctc catctcagcc cagctccccg ttcaggcgcg ccagcagcaa
     6781 cgcggcatct tcctgttcga gcaggtcggc cggtgcggtg aagccgatct gacgcagctg
     6841 cagctggccg atctgctcgc tggccagccg ctcggcacct tcctgcaggc gtttacgcac
     6901 cactgccagg ccggccgcat cggtgtgcgg catcatgatc cagagaatct cttcactgac
     6961 ccggctgcag cgatcggtgt cgcgcacggc ttcctgcagc cgctccacca ggctgtccac
     7021 cagcgcatgg ccgcgcagct cgccgagtgc gctgatggtc gccgccaggt tgacgaaccg
     7081 cagccccagc agggagaacg ccggctgctt gtagcgccgc accagctgca gctgccagtt
     7141 gagcagctcg tggaaggact tctggttgag caggttgagc gcaccgaact gatcggtctc
     7201 ggcgacactg gccgagtagc cctgccgaca gcgcaatcgc ccggcctcgg cgaggcggaa
     7261 gtgacgcacc tcgcgcacgc gcagcttgtc cggcgcatgg gcctggccac agtccaggca
     7321 gcgcgcctcg acttcggcat cgacgaagaa cgcctggcag ctgcggcagc gatagttctc
     7381 cagcggccgg tcgtaatcgc tgccgatgtg acgcaggcgc gagaaacagt tcgggcagag
     7441 cagcaggcca tccttgagga agtgctcctg ggcgccgacg tggccgcagg tgaagcagtg
     7501 cagcgacggc tgacgggcga tttccagcgt ctggcactcg gggcagacat ccacgtagtt
     7561 caaccggccg gagccacaac cgacgcacag gcgcacccga tcgaccagct cgccctcttc
     7621 cagccagccc tgctgggtca tcagctgtag ccaggcgaag gcgttcggcg actcgtcgtc
     7681 ctccagcgcc tccagcagcg gatagtgata gtgctgcgcc acgccggcat cgcgcaccgc
     7741 atggatggcg ccgtgcgggt gcaaccacag ccaggcgagc acgcgcgact cgaaacgctc
     7801 cggcgccacc ccacggttga acagcgcgaa gcgctcctgc cagagccgcc agagcggcac
     7861 cagggcgctc agatcagccg gcggcgcgcc gtcgctcagc gccttgcaag acgcgtcctg
     7921 ctcctggcag cagtagatca ggctgaagcg gtagcgcttg tccatacgca ggctgcgcaa
     7981 cgcttcgccg gcgcgcaccg ccggcagatc gagcagaacg atgtcatacg ccggcagcgc
     8041 cgcgagcgcg gaccactcgg ggtgccgctc gtattcgata ccgacaacag gggaagaaga
     8101 cgcaccaagg acagcgacgc gtggcatggg ggacatggga aggaaaaccg gataatggct
     8161 atgtgatact tgattgcctc attctacaag ttctttcagg gttattcacc agctattcgt
     8221 cggcctcgac gcttgaatat tgatcaggcc gtcattccgc accttcccta acggatgatt
     8281 gatttagcaa taattgcgca taagggggcg ttacggtaaa tccggcgccc ctttttgttg
     8341 tctgttgtct tggccggaca tcgagggaag ctgcaggagt ggtttcactg tctgcgccgg
     8401 acattcagga gccctcttca cgccggtgct gcggttaccc agattgccat ctcgggcatg
     8461 tcgccatgct gctgctcagg gtgtagtatg tagcatattg taaacattgt agtgtcggga
     8521 ggggcgtatg agcgtgatgt ctgtccgttt gccggacgag gtagagcaac agttggggca
     8581 gttagcccag tccactggca ggactaaatc ctggttggct aaccaggcta ttaaggatta
     8641 tttggcgcgt gaggcctggc agatcacgga ggtagaagcc gccttgcgtg aagcggatgc
     8701 gggtgacttc gtatctgaaa aagagatgat ggcgaagttc aatcggtggg gtatcaatgc
     8761 aggttaaatg gctgcgtaag gctgcgctga acctcgaaga tgctcacgat tacttggcaa
     8821 aagaaaaccc cagggttgcc caggagtttg cgcacgaggt gtatcgcttg gttaatctgc
     8881 tggtcgaaca gccctcgatg ggaaggtcgg gacgtgtccc aggtacgcgc gagcttgtgg
     8941 tgcaacctta cccgttcctc attccatacc gagtaaaggg agaggaaatc catattttga
     9001 gggtgtttca taccaggtta cggctgccta gtcactggta gttggatgtt gcccgttagc
     9061 cccatgcctg gcatccatcc agccactaaa tagctaatca aagctaaata ttgattgttc
     9121 gtttttgtat tttgattgcg ggcgttatat gcccttcggc ataagtgccc caagaggtta
     9181 gccactgatc taaatcttga gctgtggcat agcggccagt ctcttggaac tcctgccaag
     9241 acagcaacca agacaacaac aaggagtggc aacctcttgc gtctaaagct catttgatga
     9301 tttacttctt tactcattaa ctcaattgag tggggtgggc atgctggtta tatcggtgtt
     9361 gaaccagaaa ggagggagcg gcaaaaccac gattgccact catctagcgc gagcctttca
     9421 ggtggcgggt cgcgatgtgc tgttgatcga cagcgatccc cagggaagcg caagagattg
     9481 gtctgcagtg cgtgatgagc aaccggtgcc agtggtgggg atagataggc caaccatcga
     9541 gcgcgatatc aaggcggtgt cccacaaaga cttgatcgtg atcgatggtg ctccgcaggc
     9601 cgctgaccta gcgatatccg cgatcaaggc aagcaatctg gtgctgatcc ctgtccaacc
     9661 ctctccttac gatatttggg cggcctctga tctggtggat ctggtgaagc agcggataga
     9721 gatgaccgat ggccgtttga aggctgcgtt tgtggtaagt cgagccatca agaacaccaa
     9781 gatcggcgct gagatcagag aggcgctgga gggttatggt ctgccggtat tggcagcgag
     9841 agtgacccaa agcgttgcgt atccgagcac agcagctgca ggtaccaccg tgcttgatgc
     9901 tgagcctaac agcaatgcag cccaggaaat acgtgacttg gcagatgaag ttttagaatt
     9961 actcaaatga gttaatgagg gtgtgagtaa atgagcgtgc tgaaagctgg ccgtcccagc
    10021 agtgaaaagc gggcaatgac catgggtgat attgccggat ccgtgaagat gaagcgggtt
    10081 aatttcgacc tgccggaggc gttgcacacc aagctgaaaa tgcatgcagc tgcgcagggg
    10141 aagtccatca aggatatcat gacggacttt gttgaagcct tgccgtgatc gattgattat
    10201 caactatcct gtcgggatag tattgaatat atgagtattt ttttgcagta gtgcgtacta
    10261 aaaagcgttg atcgatcagt ctgatcaacg ctactctgta cgccagaaac gaaaaaaccg
    10321 ccttggcggg cggtttttcg aaggtactcg gagttggcgc tctttgtacc tggtaacggc
    10381 tccgtagagg gaagcagcta ccaaaagtcc cagtaagttt agcggcactt tgccgtatct
    10441 ttcaagctaa ttccctcttt acacccgtta ccgaaggcca ccacctttgg cgctttgtcg
    10501 tacccgcacg gattggaagc atgagtttgt tgccgtgtgt gggtgtggtt ggtcgggcag
    10561 aacggggaaa tctcacatac tgcccagcgt gtgatcgcgc accacagccg cccacgattc
    10621 gcaaccgtgg ggcatctgca agcagagcgt aacggggaac caaccacggc cagctcttaa
    10681 aaaacggcgc ggcagtctgg ccatcaggcg gaggctaaag cagatgcagc aaggacgggg
    10741 tgtgtctctg gagcgcgtga gagggagctg ccgcaagcag tctcgatagt ccggagcaag
    10801 gcgagtcaat cttgtgtaac tacgttattt ttaacgtagc caagcaggag ggctctccta
    10861 tcttgaagcg cagcggaaag ataggagagc ccgctgactg tggagcttgg cgacatcctt
    10921 tttgcgcggc ctttgggccg ttgtttttga gctcttcatg ggggaaccgc agaattcgga
    10981 aaaaatcgta cgctaagcta acggtgttct cgtgacagct ctttgactag gctttctaag
    11041 gccattctga tagccctgac ttcctgaaaa gccatggcta aaatttgtgc ggctaaaagg
    11101 gataaccgat ggtaaagtaa gttatccctg tcgagatact gaaaagcgtt atcctcgttt
    11161 ttcccaaaac tgttttgcca gttcgctcag agcgctagtt aactgagcga cagatttcgc
    11221 actttgcaaa ttattctgcc cggtctgtac attggtatca gcagcatcgc gtatattgat
    11281 aatactgcgg tttatgtctt cacttactgc tccctgctgc tcgaccgcag tcgctatttg
    11341 cgcgttcatg tcggtaattt cgttaacgcg ttggccaatt ccatcaagag ctgtagctgc
    11401 ttcctctgcg tgagctacac tcgtgtgcgc ttgccgacta ctttgctcca tgactgtaac
    11461 agcggattgc gctcgctctt gtagagcgct gatcatgctt tgaatatccg ttgtcgattg
    11521 ctgtgtgcga gcagcaagac tgcgaacctc atcggcgaca acagcaaaac cacgcccctg
    11581 ctcaccagca cgcgcggcct caattgctgc gttgagtgcc aacaaattcg tttgctcggc
    11641 gatccctcgt ataacgtcaa gaacttttga tatctcgtta ctttgacctt caagctcatg
    11701 aataacctga gtggcttgcc taatttcacc ttcaagggca gtgattgact ggcttgtgtg
    11761 ggctaccaga cgctggccag atgccgtctc agtgtctgct cttccggccg catctgcagc
    11821 atgctgtgca ttgctcgcaa cctcttgaat gcttgccacc atttggttta ctgccgttgc
    11881 tatttgatct gtctctgcct gctgctcaac tgtaagtaca ttgcttgact caatatcctt
    11941 tagtaggcct cgggtgtgtt cgctaagccg atttgatgca tcacctatgc gacctactat
    12001 ggcgcctgtt tcagcttgca tcattcgtaa agcaaactct atttggccaa actcatcggt
    12061 gcgcccagtg tagagggatt gacttaatgg gttattggaa atattcctgg ctctttcaac
    12121 cagtcttcca agaggagaga gaatagccaa aacactaaca gagcttaagc ttcctgacat
    12181 taaagtggct aacaataagc tgcttattga tgtatcagta agcatgccgg cagccattgc
    12241 gcttgatata atactacccc atatgagcaa gagtattttc acggaaaagc tagcagccaa
    12301 tttcggcctc gcggccttcc cgcttctcaa ttgagcatat aatttttccg cagccaaaac
    12361 ctgctcaggt tcaggcttgg tccttacaga ctggtattca acaatcgaac cattcttagc
    12421 tattggcgtt acataagcac ttacccaata gtggtcgcca tttttacagc gattttttac
    12481 tagccccatc catgagcggc cagattttaa tgtactccac atatgctcaa atgcagcagg
    12541 cggcatatct gggtgtctta cgatgttgtg aggctggcct aatagttctt cctcagtgaa
    12601 accactgatt ttaatgaagt caggattaac gtacgtgata tggctttgag gggaggtagt
    12661 cgaaagaata ttggcatctt ttgggagttc taagtttcga cccgtcactg gtaaattctg
    12721 gcgcataaga acctcaaggg ttggctgttt tattttattg ttttcggcat taagcccaat
    12781 ttcttgagcg ttacgataaa gctagcatgg aaacgatagg tgcaagcaag ttaagggttg
    12841 catcgcgcat gtcaatctag gctatagccc aaccgggcgt cagacgaagc ggcgaaagag
    12901 cgtcagagta gggccttttc cggaatttcc tgacgccttc ggcgcggcgt ctatggcctc
    12961 aacctgacac gccagccgtt agcgtgcttt attgtccgaa ttctgaggcg acccctgttc
    13021 gggggtactg ggacaccgcg aagcggatag cggtacagaa ccggaacaga tccggtacaa
    13081 aagtgggaca gaagcggtac aaaaccggga cagaagtggg acatttgcag ggcggggagg
    13141 gaacaaatcg ctcggagggc aaccgaaact aatgcgcgat aggccgctaa aacgcgctga
    13201 aaccataccc cgcaggatcc ggccctaaaa ccgccccaga agcgttgcaa actttcaggc
    13261 agtaaatgcc ctgtcttgtg tgtcgaaacg cccaaaaacg cgatacaggc ggccatatcc
    13321 tgacggagta gccgttttgc catgcgaaat cggcaattga acataaaagg cgttatgtgc
    13381 actaactttc catagttgct ctttcacttt gactagtttt cctttttgtc acacaatgtg
    13441 gaaaactaat cgagaggggt gggttatgac tagtgttgcc aagttgattg atcgacagga
    13501 tgatattgcg aatggtgttg ctgccccttt ggggttgcct aagtttgata cgtacgccat
    13561 ttgcaattta agggggggga taggaaagac ttctctagct tttaatcttt cttattacac
    13621 agatgatctt ctcgttttgg atacctgccc acaaggtaat ctttcttatt tttttgataa
    13681 taacttcttg tcttcaaatt cattaagtgt aaatgatttg ctaatgcctt attttgttcc
    13741 tggcttaggt tttgcaacta gggttgccaa aaaaatcagc gccacaaaca atttttttgc
    13801 atcaaaaaat agctatttca ttccatctag tagcgatctt tatatacttc caactcaaat
    13861 agctaacgcc ttggcgcagg caaggttaat tgctggccca aatcaagtgt caattattga
    13921 caacatgctt ttttccttga aaaaagagat tagccgagag tggggggaga cggagacatc
    13981 caagtgcttg attgacacct ccccgttctt ctctggggct acacatctgt catggcatgc
    14041 tgcagatgcc ttgattgttc cggtcagaac agatcagcaa tcaattaact ccttggagct
    14101 tttgctagat acactgtcta atccagcaag tgaatttagg cgagtaatgc catcaaatca
    14161 gcacactcca aaaatacaga tggttgtttt aacccactgt ggttggtcaa ctgttcctgg
    14221 agcaaagaac aaaccaaata atcaaacgaa agtgtatctg gaaaaggtga gagatattgt
    14281 gagtcgaaac attactcatt tcactaccca ggatcctgat aatcacattc ttttgttgga
    14341 tgattttttg ggttgtggtc gaatgtcatc agcgaggtct aagccaattg agcttcttaa
    14401 tccaggggag tcaatgacaa ttaatagagt caaggcaacc gtcaatccat ctgttatgaa
    14461 aataaggcaa gaacttaaat tcataagtca gaatatttgg taaaaataaa gccgctatca
    14521 ttggtcgcgc tgcgtttgcc gacttcctat cctggcgcga cagatgtctc tcgtcgcctc
    14581 tcgtttggag gtggttgtca aaagttaaaa atgattggtc aaatttcgac tttgattgtg
    14641 gggccactgg ccccactttc ccacagtgga gatggtgtgt ttattcccag gcattcttac
    14701 ttctttgtgg atttgctggg ttttaacgaa tcggtattcc ccggcgtatc tttattatca
    14761 cggcgacgtt gatccggttt cccggttgac ttagcaattg gtttcggacc tggtttaaga
    14821 gccatagctg ttacccttta gtgtgttaga ggatgtccct ctaactggat ctgtgggctt
    14881 tacttggctc tatcaagagt tgctgaagaa tttatgtgca gtaacaggcg ttccggtaaa
    14941 ctgacgccac ttttctcttt atctgttgta ttgaggtcat gctcactggc gggtatggct
    15001 cgctacgtaa ttgttacctc tgttcgtcgt cttccagcgc tttgcggact gcctcgatga
    15061 tgtacgcggt gaatagcaag ctggtattgc ccttctccct caacgctgcg tggcgtgtaa
    15121 aaaattctag tggcatgttc tggatgttct tggccttggt agggatcttc cctctgctgc
    15181 cgtcagtcgc cgttaccacc tcttttaggg gggctccagc gccaaggtcg tccagattga
    15241 ttagtttttt tgccataaaa acatctcttt tgtgttcatt tgatattaaa ttaatattgt
    15301 tttgtcagca tggcaagttt tgaccgcact tcttccgcca atgcttttgc ctccataccc
    15361 gctgcgctgc tgcgagtagc tgctctctcc gtcactccca aacctgactc catttggttg
    15421 gcccagtctg cccgtcggct caacttggag gtcatcatgg tgaggtgcgg cagcctggtt
    15481 agctcatcgc tgatcgctgc aaaattcttg cggctgggat tggtgcgagt catcagcaca
    15541 tgcgcttgga taggttcccc agttgcttgg ctgatttcgg aaagcactcg gttgaacctc
    15601 actagcccga tctgttctgt gatgtcgtcg tttgacgggg cgatgatcag atctgccgca
    15661 gcgatggcga ttcgaaccag ctcgctgtca aacccaccac agtcgatcag aaccagatgc
    15721 tcaccaaccg ccttcaacaa cttgatcagg gctgccttgt cgaggtttgc tctcacatcc
    15781 cagcgtagct ctgctggtcg tcggccgttg atgatggcaa ttccctggtg tgcgtccaga
    15841 tctatgatga tctccggttt cagttctccc gccagttgca ctactgtcgt cgttttaccg
    15901 acccctccct tgttatgtgc cacagcaacg atcatttgag gctcctaatt tgatgtttat
    15961 ttggttctta tagaatacaa aaaacatatt tatttggtat caaataatga aaaaaagcca
    16021 atccgtagat tggcttgatt ggcggttgtt ggctcgacaa attagatcaa ctggtttgtt
    16081 ggatctttac cctgatctgc aatttacgcg cttgatcacg atgacgccct tgcgctgatc
    16141 tctatccggc gcgtattctg gcaaccagaa acgaaaaaac cgccttgcag ggcggtttct
    16201 tcgaaggtgt tgtcagttgg ggaaccgact tcacctggta acggctccgt gcgggaagca
    16261 gctaccaaaa gtcctaatca gtttagcggc cattcggcca ttcaatcaag cttttcccgc
    16321 aactcgaccc gttaccgaag gccaccacct ttggcgcttt gtcgtacccg cacggattgg
    16381 aagcatgagt ttgttgccgt gtgtgggtgt ggttggtcgg gcagaacggg gaaatctcac
    16441 atactgccca gcgtgcgatc gcgcacatca tcgagagagg atcttggcga ggtggttaag
    16501 cccgatcccg ttgggctgtc catcaggggc ttgtcccctg tgggcaggag ggcttatcca
    16561 cggagcgttc tttctcttgg tggttccacc atctcagcgg ctacttagat cgatctcgat
    16621 gcgcctaaag cctatcccat tggcggtgtt ggcggcggca tcgatgctct tgaacacccg
    16681 ccagcctccc cgttgtcgtt ccaggaaaat ggtctcgctc tgtttgccga acttcaccag
    16741 gtgcaggtga tagccctggc ccatcggggt gggtacgatc agcgccttgg caaatccgcc
    16801 ttggtcaaac gtccacttcg cttgcagctc ttccatatca caatcctatt ttgactaatc
    16861 aaaatcgaaa cttgattgta acggaggacg gggctgctgg ccagccctgt ccagtaactc
    16921 ccacaacagc cgcaccgcat accaatggtc ctgtcgcgtc cgctcggaaa ggtgtctctg
    16981 gcgggcccaa tagcggtgga gatgggcccg tcctacctgg ggcggtagcc tcaccccctg
    17041 ctcatgctga cgaatgtcct ctaaaacggc aatcagcctg ctgacagtag ctcttcggct
    17101 ggttttgcca ccgtgacgca ggtagacatc gacccgggct ctgatccacg tttccatgct
    17161 gctcatgatc gttaccccag gtaggtgttg gtgacatcga ggcggccgtg gcctagctcg
    17221 gcggcgaccc gctcgcgggc ctgctgatcg agcgcccgcg ccgccgccac ggtgagcccg
    17281 agtcgaactg ccaaaaaccg atggtgtgct gcgccgtggg caacccccgc agcgaccggc
    17341 gcgggggccc ccactagggc ggcgtagcgc tcttgggcgt aggcgtgtcg ttcgccgtgc
    17401 gagcgaatgc ccgcgctgcg caactcggca taggcctccg cgcgaaattc acgataggtc
    17461 tgatgcgcgg ggatcaggct gcgcgcgttc tcttggatat tggccgcgtt ggctagcaga
    17521 aatttttgct ccagtgggtt ggttatcggg acatcgcggg ccagaccacc tttggtgccg
    17581 acctcgatgc gcaccatgcc atgttgggcc tgtgctaggg ccctcaccgc gtccaatttc
    17641 gccgcctcct cgaacctgag cccaaaagcg cgttgcaggg ataggatggc ggccacgcgt
    17701 tcggagacgg tagccacggc gtggtcgtgc tgggacaacg atacggcccg atcagtggtg
    17761 gcgatcccgc tacggatcgg tagtccagcc tcgtgcacgg gatcgagccg taccaatcga
    17821 tcgccacggg cgatctccaa tacgcggtta acggcggaga gcgcattttg ggcggtagcg
    17881 gggctgatct ccccttgctc caatcgggtg agcaggtggt cggcatagcc gcgcagtgtg
    17941 tcagtcacga tctggcgcat atcacggatg cccgcagcct cacgcgccca ggcggcgaac
    18001 tgggaccagc gatccgccat ggtggcgatc gaactgtggc tttgcatccc ctcgcgcagg
    18061 gcattcagcc cggcataccc catgtcgcgg ctgccgaggc caaaatttct cgcgttcggg
    18121 tgggctctat cacatcgcgc catatcaaaa tcctattttg attgatcgtt ttgttgtttt
    18181 gatgccccat cccctgatca tggtgttgag tgttttgcgc atgtttgcga ctgcgcgtgt
    18241 cgtggggcat cggttttaaa ctccttacgc ggtgagcgtg ctgtggttcc gaggaacggg
    18301 gggctgctat ggcagggggc tcctgcaggc agggcgctag tcgtggtgcg actgcgccta
    18361 gcgtccggct ggcctgtgag tgacgatttc gtcggttttc gtgcctggga gagctggcgg
    18421 catggcccga gggctctgga gtggcgccgg gtgggcgctg gccgtctctg tctgacagag
    18481 acggcggggg gctatcgtcg catcacggtc gcatcagcta tccgcgcgat tgaggcagag
    18541 gccgaacagc ataaccactt cggttagcgt gatgccgggc atcgatgtgt gtgcctgtgt
    18601 tgccaatggc gtatgacccg agggtctgca ttaccaatgg tgcattgcct tgtggcgcat
    18661 gacccttgcg ggttgccacg cagatctggt ctgcgccgat gcaggtttta tggtcgcatc
    18721 ccacccacgc tggctatgcc tgtttttcag gctggccgtc caccctcctc cttagatttg
    18781 gatgcgcccc tgattatcca gtggagctcg actggcgagg gggcttgatc ggtcgctggt
    18841 ttcagcgatg gtcaaggctg gtcctcagtt ggatgagtca tcagtatcat gtaagtgatg
    18901 gagtgttgca ataagtgaag gatgcaagcc gcgtgctgcg gctggtcaat acggtgaaca
    18961 gcaagagcgg cgaggtttgc cgcgtcatcc acgttgagca aggcccggac ggcgagccga
    19021 tccggtacaa cttcgagtat ctggccgagg cgctactgcc ggtggcccgc tgggacatcg
    19081 aggccgaccg caaggcccgc gccgaccgtc gccagttcaa gctgctgccg ggcggccaaa
    19141 ccggcaacct gcgcacgctc aacgggcggc aactggcgtg ggatcgtctg gaggacttgc
    19201 gcacgctggc ccgtgagctt gacccacggt ggaactaccg cagcgccgag cttatgacgc
    19261 tgtacgccaa ggccaaggct cacgaagccg gggaatcagc cgggacatgg ccgcagagcg
    19321 ccacaggaag cgtgacgagg cccgcaggcg ggccgctggg gctgtcgatc gtgcgaccta
    19381 tgaggccaac tccgcgagcc gtcagaagcc gtgggaagcc ttgggcatga gccgggcaag
    19441 ctggtatcga gcaggcaagc caacgccagc ggttgagaca agtccctgcg tattacaggc
    19501 cgctgcgggt gattcagatg cgtgagacaa gtccctgcgt attactaatg gcgaagccta
    19561 cgcccggcgc gaagcgcctg cctttgagta gcccccagca ttctaaaaat gcgagtagcc
    19621 cgccgcccgc agggcggccc cctcgtccag tttgtcgggt ggctgtcatg agccgccccc
    19681 gtcgatcctt tccgcccgcg ctgcattcgt tgcgggcaat gacggtgcag gaaacgctag
    19741 accggctggg cctgtactgg aagcgtgatc ctgactttgt gccggtgaag gacaaggcca
    19801 cggtacggct gaatgtgtcc atcggtggcg gtggtgttga gctactggcg accgggccga
    19861 agtggtacga cacgcgggca gagcagggcg gcggcggtgc catcgacctg accatgcacc
    19921 tgttcaggtt gccattcgta gatgcggtca aacggctgtc gccttgatcg tgtttgcaag
    19981 atgcctccgg cggccctgcc gggggccaaa cggtcgcgtt tgatcctcgg gagcaggggg
    20041 acggcctacg gcctaaaccc ctgccccact cggggagcgt gagccgttcc gagggcatca
    20101 agcgactttc gcggcataaa cggtgcctcc tacgggctac cccccattta ttccacggtt
    20161 cgcttgaccc cctctccact cgaaaacccg gacggcggac gacctcacag gcggcccgtg
    20221 gcggcgtttt ctcgacgtgg ccctgcctgc cccctttctt accttctcaa aacgcgctgt
    20281 aggcccgttt ctggccggag ccgggcggcg ggcggaaagc tccgcttttc gttcgacggc
    20341 tggccgacaa cgagccgaag gcgaggcgtc agcacggtgt ttcaccaaaa acgagcagcc
    20401 gaccgggcag cggtacgtta cgaaaaccgc tcgcatatcg tatctgtatt gcgtatcata
    20461 tctgtattga tacgatttac actgatacgg tacgaaagga gcaacgatca tggcacgtca
    20521 gggcatcact tttgagcagg tcgccgccgt cgctgatgcg ctggcaggcg agggtcagca
    20581 gccgaccatc cgggcggtgc gggagaagct gggcgacacc ggcagcccga acactattca
    20641 caagcacttg accgcgtggc gcgaggcccg cccggtggcc gcagccgctg cgccggaact
    20701 gccgcaggcg ctgaccgctg ccattgccgc cgagatcgag cgggccgcat cgcgggcacg
    20761 cggcgagatc gagggccgtc tggtgcaggc gcaggcggag gccgccgaac tggccgccgc
    20821 tggcgaggtg ctggaaggcg aacgcgacga gctggccgag caggtggccg tgctgaccac
    20881 tgagcgcgac acgctggcag gcaaagccgc ccagcaggcc accgacttgg ccgaggcgca
    20941 gcagcgcatc gagcgcgagc agcaggcggc agagtctgcc cggctggagg tggcaaccgc
    21001 ccggcacaag atcgaggcgc aggccgagcg cgtgagcgag caggccgccg agcttgagcg
    21061 cctacgcgcc gcactggccg aggcacagca gggccgcacc gccgccgaac aacaggccgc
    21121 cgtgctggcc gccaagctgg aggcgtgcgc cgaccgtgtg agccgcgcag aggcccgcgc
    21181 cgagcagatc gagcagcagg ccgccaaggc tgcacaggcc cacgacaccg cccgcgccgc
    21241 agcagcgcag gaaacccggc agacgcaggc cgagcgtgac gaggctcgca aggtggcagc
    21301 agaggcccgc gagcaggccg cacgacttgc cgggcagctt gaggcgctgc aacggcagca
    21361 ggacaaggcc gaggccgccg agaaggccac gaaggcaccg aaagggaagg ggggcgagtg
    21421 atgccaagcg ccgcagaatt tcaggcgctg tccgatgagt tgcggcagct tggggcggtg
    21481 atcgtgcagg ctgcgaacct gggcgatcag gagcttgcat tgtgggccgt gggggcgctg
    21541 tcatccgcag ccgcccggcc tgcatggtgg gcgagagagg ccgcagacag cgaagctgtg
    21601 ggatgcaaat aaagtcccat cctaagctac gccaattttc aggactgttt tgaaagactc
    21661 aggcttggca ggcgggtaaa gtgtcattct gaaaggatcg cgtggcattg ggcgcggcct
    21721 gaatcgtgaa aataaagtct catactttcg agcgtctgaa tcgtcgccca ctaccgccgg
    21781 gactgagaca ccaacaaggg gggcgtatgc ccaaaacccg aaaacacctc accccgaccg
    21841 aagcagaggc caaggggctt ctatgccgta agcacctcaa ggaacgcctc cgcctcatgc
    21901 cgggactaaa caccaagccc gctggcagtg tctggcaagg tcagggggct tatgatgtgt
    21961 acaacccagc cgagtgcgtg ccgtggcgct ggatgcctgg gcgtgcccaa gtccgtcgcc
    22021 agcacgtcgc agcgcaggca aaagacctga tcgccgcagg ctgcattgtg ctcgacaccg
    22081 aaaccaccgg cctcggtgat gacgccgaga tttgcgagat aaccatactc gacgtgaccg
    22141 gcgcaccgat cctcgacacg ctggtacgcc cgacccggcc aatcccggtc gaggcgacag
    22201 cgattcacaa aatcaccgac gccatggtgg ccagtgcgcc gagctggccc gaggtggccg
    22261 agcagtacgc cgccgccgtt gctggccgaa ccgtcgttgc ctacaacgtc gcttttgatg
    22321 cgcgcttgct gcggcagacc tatcagatac acggactcac cgcgccagtg ttgacgaccg
    22381 cttgcgcgat gctgatgtat gccgagtggc atggagagta cgaccggagc cgcgaccgct
    22441 ggcgatggtt gaagctgatc gaggctgcga ccgactgcgg cgtggcagaa gacggcgcac
    22501 accgcgccct tgccgacgcc cgcatgacgc tgggtgtgct gcgatacttg cagcgccgca
    22561 cgaacggacg gcgaccggca gggccgaaag tggccaccgt cccgcaggag gctttgccct
    22621 ctgttttagg atgaaactct atttcaaaga atgagacttt atttgtacgg atgaatcttt
    22681 attcgcatcc cacacatggc ttctaaccac gcttcgtgca tccagaatgg ggctattttt
    22741 ccgtgctgaa gtgtgcaaag cggattgagc acccggcgtg ggttctttca tgtctcgacg
    22801 gagagcaaca ggccgtccgc atggacggaa aagactggta gtgctttcgg ctggcccttc
    22861 ttcttgcctt gcgtttcggt tggcttgagg tcgccccaaa cgccttgcac ggttttgttc
    22921 agttcgtcga tgaagcgttc cggcatggtt ttcaagagtt ctgcagtgat tgcgttcgcg
    22981 tcctcaaatt gctttcttgc ttcggcttcc tttttccgtc gtttttgccg ctcctgttcg
    23041 tattcgtcta aggtttgcct gtgtctgcgc tgtgcttcag cttccgcttc ttcagcttgc
    23101 cttcgtgctt cctctttggc tttctgtcgg cgtgcttcac cctctgctgt gagtgctggt
    23161 tttaccagtt cgccagactt ggcctcgatg gtgatcgaaa gcggttcgcc gcgatggtct
    23221 accagatcga aaggcagacc atccgcatcg aatgccgtga ggtaaagatt ggccccatag
    23281 accttgtgcc ccggcctcac agcttcgtat ttttctgctg ctgcgtgcag tgcttccgct
    23341 aggcgttctg ccgtgatttc tcctttgatc ttgattctca tggcaacctc catccgtagg
    23401 tgccatccga tgcgggcttg acgtagcaca cgcctttttc gacgtaccac cccggcctat
    23461 cgcacttcgc caagctggcg aggcttcccg tttgagcgaa gcggtaggcc aagcgcccct
    23521 ctggcgtgtt ggcccatgcc gccgccgctt tctcgtcctt ggcttcggtg tatcccgcgc
    23581 cgtatccggc ctgatagccc gaatccttgc cgctgctgtg catgtaccag ccgaacaggc
    23641 cgacgcacag gaaggccacg gcgatgcagc ccgccgccca ctgccacatc tgctttgctg
    23701 atgtgttgtg cgcgacctct tgcgctgctg ctgctaccgc ttgcgccaaa tccgccttgg
    23761 ctgcttccgc tgatgctttc acggttgcat ccgccgttac cttgaaattg accaaggtat
    23821 ctttggctgc ttgtgctatc gcttgcggga acttctcata ctggccttgg tagtgttgca
    23881 aggccatgag caccagccac agcgcatcat tgtttttcag gccgagtgca tcccgaaccc
    23941 ggtaaagact ttgccgctcc gcgtcactag gttgcctgcc gagcagcttt gcaaagctgt
    24001 cgtctaggtc actcatggac tacggcctcc aatacctttt tggcctcgtt gcgccaccgc
    24061 gtaagctccg cacggttgcc aatgggcaat tccttgagtg ctaccgcaat gctcatgcgc
    24121 ttgctgtaaa tgtcatcgct cacacggtcg gccatgtccg ggaatgtcac cgatttcccg
    24181 ccgcgttcct ctaccgccgt gcgcagcttg gagccgttgt aaagctcgaa cttattttct
    24241 tccccgaagt gtccattgcg taccacatga acatccgcat tcggaattgc gtccatgtat
    24301 tccttgagca gttcgaggct atcccgttgg cggttaatca cccacagcgt gaccagcttc
    24361 cgcttgagtt cttcaagcgt gctattcagt gtttcaccgt aggcgctcac gcccttgtta
    24421 ttccgtgctg ccgtgttgat taccacgacg ctatccggct tgctatcgca caagttcact
    24481 agctgaatcc atccgtccgc ctcatccaga ttgataagct ccgtttccgt gctttcttta
    24541 taggctttcc atacgtccgg gttagaggtg tcagactcaa tcagcaagac gctttcgccg
    24601 cgctcttgca ggtaatcaac cgttgccatc gtgacaagcg acttgccaac gccgcctttg
    24661 ctgccaccga tcaggtaaat gcttttcgcc atgttgctta ctccttaaat gtcgtcgctg
    24721 tcaggtttcg gggtgaatgt cgcctttgat gtatccgcag gcttcttgac ggcggggcgg
    24781 gggcggggtg tgtctcccgg tgcttgcacc ggagcttttt tcgctggctt tgctctctgc
    24841 aagtagctct tgagtgttgg agttgcgatg ctcagacctt caccgcgcag cgtctcggaa
    24901 atctggtcaa gcgtgtatcc acgcttttgc aacaaggcga tttccttcga gagtatgcgc
    24961 acggcatctt gcttgctgtg ctcttgcttc tttttctcga ctggcggcat ctctcgcagc
    25021 tttgcagcga tagcctctag ctgttctgtc gtgcacttca tcgtgctaac tcctttgctt
    25081 acttgttgcg gagttgacag catagcgcca tttgtgcttg ttgcaaagtg cgtcccgtgc
    25141 acctaaactg ctgatacgat agtagagcgg atgagcaata caggatgacc gttgtaacac
    25201 acatggcttc gccacgtggt tccaacggac gcctgcccat tcggcgcttc gcttctcacg
    25261 gtctggctta tcctgcaagg ggtatcccct tgaccccgga cagtgcggcg ctctcgcttc
    25321 ttactgtcca agacacaccc cgccccccgc cccggcgaga aggagacacg atgccatttg
    25381 aaacgcaggg gccggaaccg ctggacgccg ttatcaatgt acggctgacc gcagcggaga
    25441 aggcccgctt gaaagaggat gccgaccttg ccgggttgag catgtccgag cttgtccgcc
    25501 gccgctactt cggcaggccg atcattgcca acgccgacgc cgtgatgctc aaggagctgc
    25561 ggcgcatcgg tggattgctc aagcacatcc acaacgaaag cggaggcatt tacaacaagg
    25621 acacagccgg ggcacttgtg gccctgaaag cctacatcgg gaaactgagc cgtgatcgtc
    25681 aagaaggtta agaacccgca gaaggcagca agcaaggcgg ttcgcgtttc tcgcctaacc
    25741 gactacatcc gcgagccgga gcgtgagaac tcgcaggaga agtgcatcca tgccggggcg
    25801 cgtggattca tcaccgatga accacagagc cagacggcag aaatgattgc cttgtcacaa
    25861 gaggcagtgc gaagcaagga cacgatcaat cactatgtcc tgagttggcg agaaggcgag
    25921 cagcccagcc cggagcaggt cgaagaagcg gtaagcattt tcatggatga gctaggtgtt
    25981 aaagaccatc aagccatcta tggtttgcac gccgacacgg acaacttgca cctgcacctt
    26041 gccatcaacc gcgtgcatcc tgaaacgctc aaggtggtga agatcaataa cggcttcgac
    26101 attgaggcag cgcacaaggc gatagcacga atcgagaacg cacaaggctg gcagcgtgag
    26161 cagaacgggc gttatcaggt gttggagaat ggtgagttag gccgggagca catcgacaag
    26221 gacaagccgc gccagccagc ccagccgaag cgcgacatgg aaaaccgcac cggggagaaa
    26281 tccgccgaac gcatcgccat tgaggacggc gcaccgatca tcaaaaaggc gcagacgtgg
    26341 gagcagttgc accgcgagtt agcagccaag gggatgcgct acgagaaaac aggcagcggg
    26401 gcgacgctct ttgtcggtga tgttggcgtg aaggccagca gcgcagaccg ggacgcgagc
    26461 ctatccaagt tacaaaagcg actcggagct taccagccgc cgccgcagcg tcagcaggta
    26521 gcacagcgcg agccagagcc gatcaagcca gacgtgccgg gatggaagga ttacatcacc
    26581 gggcgcaagg cgcactacgc ggaaaagaac gcggccaagc tggcactgga caagcggcag
    26641 gagcaggagc gcaagcagat tgccgagcag cagaaagccc gccgcgatga actcatgcgc
    26701 ggcaactgga agggtaaggg cgaagtgctc aacgccatgc gcagcgtgat tgccgccgag
    26761 caggccgcag agaaagcagc cttgaaagag aagcaccaga agcagcgcga gcagcaccgg
    26821 cagcagttcc ggccctatcc cgacctggag cagtggcagc ggatgcagaa aagcccggag
    26881 cttgccgagc agtggcggca ccgcgccagc gagccgcagc gcatcgaggg cgcgagcggc
    26941 gagccgccga cgccgcgaga catccgcgcc tatcagcctg aaatcgtggg ccagcaggtg
    27001 cattacagcc ggaaggaaga agcgggggcg ggcgggggtg tgtctttcgt ggacaaggga
    27061 aaaagcatcg atattcacga ctggcgcaac cgggacagca cgcttgccgc cttgcagcta
    27121 tcggcgcaga agtggggcag cttcaccgta accgggaacg acgaatacaa ggccatgtgc
    27181 gcgaagttag cagcagagca cggtttcaag atcacgaatc ctgagcttca ggagcgcatc
    27241 cagcaggagc ggcagcggat acagcaggag agggcgcagg cgatgaaatc ggagcagcta
    27301 aagcagtttg agctgtacgc ggaagcggta ggcgcggagc gctaccgggt aacgtccatc
    27361 aagatgcagg cagacggaag gaagcaaacc ttcatcctcg acaagaagga cggcatcacg
    27421 cggggcttca cgccgcagga gatcgagcag cgcacgccgg agatgctgcg cctacagcgc
    27481 cggggcgaaa acctctacta cacgccacta tcggacaaga agcatcacat cctcatcgac
    27541 gacatgaacc gggagaagct ggagcggctt atccgtgacg gctaccggcc cgccgttgtg
    27601 ctggaatcaa gccccggcaa ctatcaggcc atcatcaccg tgccgaagct ggggacggcc
    27661 cacgacaagg acgtgggcaa ccggctgagc gatgccctga accgtgaata cggcgacccg
    27721 aagctatcgg gagccatcca cccgcaccgc gcacccggct acgagaatcg caagcccaag
    27781 caccagcgcg aggacggcag ctatcccgaa gtgcgcttgc tcaaggccga gcgccgcgag
    27841 tgcgtcaagg cgctggccct gtccagccag atcgacgccg agtatcagcg tcaggccgcc
    27901 ttgaaggcgc agcagccaga acgcagcaaa gccaagcccg ccttggagct tgcagcggcc
    27961 agcggcagcg cgatcgacgc ttaccagcgg cattaccgcg acgtgatcaa gcggcagcgt
    28021 ggcggcgagg tggacttgtc ccgcgtggat tccatgattg ccgtgcggat gcgcgttacc
    28081 ggccacgatc aagccgccat cgagggcgct atccgccagt gcgccccggc cacccggcag
    28141 aagggcgagg ggcgcgactg gaacgactac gcgcagcgca ccgcccgcta tgcctacagc
    28201 gccgcaggcg accggcaagc cgccgagctt gggaagtacc gccagcagtg ggagaagctg
    28261 gaagggcgcg agcctgtacg ccagcaggag caggccaagg cgcagaagat cgagcgcgac
    28321 aactcacccg gcatgagtcg ataagacttg atgtaactac aaaaagacgc tacaataaga
    28381 acacaatgga acttgaatgg gacgccgata aagcggcacg aaacctgaaa aagcacggcg
    28441 tttccttcga ggatgccgag cttgtttttt acgactccgg gcgggttgaa gcctacgacg
    28501 gacgcgagga ctacggggaa gatcgttggg caacgattgg gcttgcctac tcggctgtcc
    28561 tgtatgtggt ctacaccgtc cgacacgagg aaaccatccg ccttatctct gcgaggaaag
    28621 caaatgccga cgaaagaaag caatatcgtg aagcgaactc ttgacctcaa gaagccgcca
    28681 cagttgagcg ccgagcagaa ggcgcgactg gatgccgtgg cctcgatgcc ggatgagcag
    28741 atcgactata gcgatgcacc ctatctgcct gatgctgtct ggatgaaggc agcggagcaa
    28801 ttgccccaca ccaagaagca aatcacgctg cgcattgatg ccgaagtgtt ggagttcttc
    28861 aagcacaccg gcaagcgtta tcagtcgcgc atgaatgctg ttttgcgctc ctacgttgag
    28921 gcgcacaagg cgcacgcgaa atgagcggcg acgacaagca gcttgagctt gaagccctcg
    28981 ccgccgtggg cgaaatgctc ttgttcgacc aagccagagg
//
