LOCUS       NZ_AP022205            25896 bp    DNA     circular CON 02-DEC-2023
DEFINITION  Klebsiella sp. WP7-S18-ESBL-04 plasmid pWP7-S18-ESBL-04_4, complete
            sequence.
ACCESSION   NZ_AP022205
VERSION     NZ_AP022205.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00194574
            Sequence Read Archive: DRR199410
            Assembly: GCF_014169555.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella sp. WP7-S18-ESBL-04
  ORGANISM  Klebsiella sp. WP7-S18-ESBL-04
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Sekizuka,T., Itokawa,K., Yatsu,K., Inamine,Y. and Kuroda,M.
  TITLE     complete genome sequences of Klebsiella sp. WP7-S18-ESBL-04 isolated
            from wastewater treatment plant effluent
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25896)
  AUTHORS   Sekizuka,T., Itokawa,K., Yatsu,K., Inamine,Y. and Kuroda,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2019) Contact:Tsuyoshi Sekizuka National Institute
            of Infectious Diseases, Pathogen Genomics Center; 1-23-1 Toyama,
            Shinjuku-ku, Tokyo 162-8640, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: flye v2.5; minimap v0.2-r124; racon v1.1.0;
            circlator v1.5.3; Pilon v1.18; SPAdes v3.11.1; A5-miseq v20140604
            Genome Coverage                   :: 206x
            Sequencing Technology             :: Sequel; NextSeq 500
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/02/2023 11:02:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,178
            CDSs (total)                      :: 5,059
            Genes (coding)                    :: 4,904
            CDSs (with protein)               :: 4,904
            Genes (RNA)                       :: 119
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 51 of 155
            Pseudo Genes (incomplete)         :: 103 of 155
            Pseudo Genes (internal stop)      :: 20 of 155
            Pseudo Genes (multiple problems)  :: 16 of 155
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP022205.1.
            Annotated by DFAST v.1.2.3 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25896
                     /organism="Klebsiella sp. WP7-S18-ESBL-04"
                     /mol_type="genomic DNA"
                     /strain="WP7-S18-ESBL-04"
                     /isolation_source="wastewater"
                     /db_xref="taxon:2675718"
                     /plasmid="pWP7-S18-ESBL-04_4"
                     /geo_loc_name="Japan:Tokyo"
                     /lat_lon="35.5619 N 139.7531 E"
                     /collection_date="2018-08-06"
     gene            complement(join(25520..25896,1..100))
                     /locus_tag="H7R69_RS25680"
     CDS             complement(join(25520..25896,1..100))
                     /locus_tag="H7R69_RS25680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009268104.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="WP_218188518.1"
                     /translation="MNLTDGVLAALLLGGWYGGFAGAIGMTIADLLDPVYITVAPKTFV
                     LKLCIGLITGLVAHNFAKINHSNNKGYVFKWVLISSICGLTFNVIFDPIVGYFYKLYIL
                     GQPQELASILAKLSAVTTFINAVVSVILVSLIYNSIISPLKKSGFLLIENKEDN"
                     /name="ECF transporter S component"
     gene            <98..>643
                     /locus_tag="H7R69_RS25685"
                     /old_locus_tag="WP7S18E04_P40010"
                     /pseudo=""
     CDS             <98..>643
                     /locus_tag="H7R69_RS25685"
                     /old_locus_tag="WP7S18E04_P40010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011349284.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(1289..1615)
                     /locus_tag="H7R69_RS25690"
                     /old_locus_tag="WP7S18E04_P40020"
     CDS             complement(1289..1615)
                     /locus_tag="H7R69_RS25690"
                     /old_locus_tag="WP7S18E04_P40020"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227674294.1"
                     /translation="MKTMPERFIDELNKTVQGVWDDLKPTETQGKKKGQPKALPVFSIH
                     ADGLVLSVETWKNPRRVLNPLCTLQHGEIAPFWMHEAWLEAMRRIVDLLDTLTAAPAEA
                     LESQ"
                     /name="hypothetical protein"
     gene            complement(1727..>2260)
                     /locus_tag="H7R69_RS25695"
                     /old_locus_tag="WP7S18E04_P40030"
                     /pseudo=""
     CDS             complement(1727..>2260)
                     /locus_tag="H7R69_RS25695"
                     /old_locus_tag="WP7S18E04_P40030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]; GO:0019748 - secondary metabolic process [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family protein"
                     /name="aminoglycoside phosphotransferase family protein"
     gene            complement(2293..2898)
                     /locus_tag="H7R69_RS25700"
                     /old_locus_tag="WP7S18E04_P40040"
     CDS             complement(2293..2898)
                     /locus_tag="H7R69_RS25700"
                     /old_locus_tag="WP7S18E04_P40040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            2993..5890
                     /locus_tag="H7R69_RS25705"
                     /old_locus_tag="WP7S18E04_P40050"
     CDS             2993..5890
                     /locus_tag="H7R69_RS25705"
                     /old_locus_tag="WP7S18E04_P40050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            <5961..7880
                     /locus_tag="H7R69_RS25710"
                     /old_locus_tag="WP7S18E04_P40060"
                     /pseudo=""
     CDS             <5961..7880
                     /locus_tag="H7R69_RS25710"
                     /old_locus_tag="WP7S18E04_P40060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138082.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(7794..8339)
                     /locus_tag="H7R69_RS25715"
                     /old_locus_tag="WP7S18E04_P40070"
     CDS             complement(7794..8339)
                     /locus_tag="H7R69_RS25715"
                     /old_locus_tag="WP7S18E04_P40070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227674296.1"
                     /translation="MRIKIKGEITAERLAEALHAAAEKYEAVRPGHKVYGANLYLTAFD
                     ADGLPFDLVDHRGEPLSITIEAKSGELVKPALTAEGEAHRQKAKEEARRQAEEAEAEAQ
                     RRHRQTLDEYEQERQKRRKKEAEARKQFEDANAITAELGVVCGRGRNPTLRLWPAIFSG
                     EIDVFPSERRNMGQEIGR"
                     /name="hypothetical protein"
     gene            complement(8336..8974)
                     /locus_tag="H7R69_RS25720"
                     /old_locus_tag="WP7S18E04_P40080"
     CDS             complement(8336..8974)
                     /locus_tag="H7R69_RS25720"
                     /old_locus_tag="WP7S18E04_P40080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6753 family protein"
                     /protein_id="WP_009873359.1"
                     /translation="MSDLDDSFAKLLGRQPSDAERQSLYRVRDALGLKNNDALWLVLMA
                     LQHYQGQYEKFPQAIAQAAKDTLVNFKVTADATVKASAEAAKADLAQAVAAAAQEVAHN
                     TSAKQMWQWAAGCIAVAFLCVGLFGWYMHSSGKDSGYQAGYGAGYTEAKDEKAAAAWAN
                     TPEGRLAYRFAQTGSLASLAKCDRPGWYVEKGVCYVKPASDGTYGWRLP"
                     /name="DUF6753 family protein"
     gene            complement(8967..9650)
                     /locus_tag="H7R69_RS25725"
                     /old_locus_tag="WP7S18E04_P40090"
     CDS             complement(8967..9650)
                     /locus_tag="H7R69_RS25725"
                     /old_locus_tag="WP7S18E04_P40090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein mobD"
                     /protein_id="WP_009873358.1"
                     /translation="MAKSIYLIGGSKGGVGKSLVTMATVDYLQERGESVLLIESDTSNP
                     DVWKAYKESTETELINLDEADGWIQLVNLCDSKPDSVVVINTAARNNKGVSAYGETLNS
                     TLEELKRKLVTLWVINRQRDSLELLKEYMDAIPNADVHVVRNGHFGEEKKFELYNGSKL
                     RTAVEERGGKSVTFPDMADRVSDDIYSKRMSIAVALKELPIGNRAELTRWRNEAKKVLE
                     AVVHE"
                     /name="protein mobD"
     gene            complement(9663..10019)
                     /locus_tag="H7R69_RS25730"
                     /old_locus_tag="WP7S18E04_P40100"
     CDS             complement(9663..10019)
                     /locus_tag="H7R69_RS25730"
                     /old_locus_tag="WP7S18E04_P40100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein mobC"
                     /protein_id="WP_047706562.1"
                     /translation="MKYTTEQLEAIASKLREMPPVEKKKQEHSKQEAVRVLSKEIAALQ
                     KRGYTLDQISETLRGEGLSIATPTLKSYLQRAKPAKKAPVQAPGDTPPPLPADKKPADT
                     SKATFTPKPDSDDI"
                     /name="protein mobC"
     gene            10329..10640
                     /locus_tag="H7R69_RS25735"
                     /old_locus_tag="WP7S18E04_P40110"
     CDS             10329..10640
                     /locus_tag="H7R69_RS25735"
                     /old_locus_tag="WP7S18E04_P40110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003869.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_009873356.1"
                     /translation="MPFETQGPEPLDAVINVRLTAAEKARLKEDADLAGLSMSELVRRR
                     YFGRPIIANADAVMLKELRRIGGLLKHIHNESGGVYSKETAGALVALKDYFRKLNDDR"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            10630..13302
                     /gene="traI"
                     /locus_tag="H7R69_RS25740"
                     /old_locus_tag="WP7S18E04_P40120"
     CDS             10630..13302
                     /gene="traI"
                     /locus_tag="H7R69_RS25740"
                     /old_locus_tag="WP7S18E04_P40120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI/MobA(P) family conjugative relaxase"
                     /protein_id="WP_182930712.1"
                     /translation="MIVKKVPNPKKSASKAQRIGQLTSYVRSPESESPQEKCLYAGARG
                     FMMDDPKSQTAEMIALSQEAVRSKDTINHYVLSWREGEQPSPEQVEEAVSIFMDELGWK
                     DHQAIYGLHSDTDNIHLHIVINRVHPETLKIVEKNRGFDIELAHKAIARIEHAQGWQRE
                     QNGRYQVLENGELGRAPYDPEKPRQPDQKKRDMENRTGEKSAHRIAIEDGAAIIKQAQT
                     WEQLHRELAAKGMRYEKTGSGATVFVGDVGVKASDVDRNASLAKMQKRLGEYQPAPQRQ
                     QVAPREPEPIKPDVPGWKDYISGRKAHYAEKNADKLAQDKRQEQERKQLAEQQKARRDE
                     LMRGNWKGKGEVLNAMRSVIAAEQAAEKAALKEKHQKEREQHRQRFRPYPDLEQWQRMQ
                     KSPELAEQWRHRASEPQRIEGDRSEPPTPRDIRAYQPEIVGQQVHYSRKEEAGRGGGVS
                     FVDKGKSIDIHDWRNRDSTLAALQLSAQKWGSFTVMGNDEYKAMCGKLAAEHGFKITNP
                     ELQESIQQERQRIQQERVQAMKSEQLKQFERYAEAVGAERYRVTSIKMREDGSKQTFIL
                     DKKDGITRGFTPQEIEQRTPEMQRLQRRGENLYYTPLSDKKHHILIDDMNREKLERLIR
                     DGYQPAAVLESSPGNYQAIITVPKLGTAHDKDVGNRLSDALNREYGDPKLSGAIHPHRA
                     PGYENRKPKHQREDGSYPEVRLLKAERRECIKALALSSQIDAEYQRQAALKAQQPERSK
                     AKPALELAAASGSAIDAYQRHYRDVLKRQRGGEVDLSRLDSMIAVRMRVTGHDQAAIEG
                     AIRQCAPATRQKDEGRDWNDYAQRTARYAYSAAGDRQAAELGKYRQQWEKLEGREPVRQ
                     QEQAKAQKIERDNSPGMSL"
                     /name="traI"
     gene            13369..13593
                     /locus_tag="H7R69_RS25745"
                     /old_locus_tag="WP7S18E04_P40130"
     CDS             13369..13593
                     /locus_tag="H7R69_RS25745"
                     /old_locus_tag="WP7S18E04_P40130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin MazE family protein"
                     /protein_id="WP_043149934.1"
                     /translation="MATAHVNQRVQKHRDALRMAGLRPVQIWVPDTRRPDFAEECRRQC
                     LLVAQADSADTAMQQFMDEALADVDGWTE"
                     /name="antitoxin MazE family protein"
     gene            13590..13916
                     /locus_tag="H7R69_RS25750"
                     /old_locus_tag="WP7S18E04_P40140"
     CDS             13590..13916
                     /locus_tag="H7R69_RS25750"
                     /old_locus_tag="WP7S18E04_P40140"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019303585.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003723 - RNA binding [Evidence IEA]; GO:0004521 - RNA
                     endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_009873354.1"
                     /translation="MMRGDLVTIAMQGDFGKPRPALVVQANQFSEHGSVTVLPVTSTLN
                     AAPLLRVTVQPSAENGLQKPSQVMVDKAMTVLRSKVGPAFGRIDADALLEVERCLAVFL
                     GIAK"
                     /name="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     gene            13913..14239
                     /locus_tag="H7R69_RS25755"
                     /old_locus_tag="WP7S18E04_P40150"
     CDS             13913..14239
                     /locus_tag="H7R69_RS25755"
                     /old_locus_tag="WP7S18E04_P40150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009873353.1"
                     /translation="MKTIYTIPAPDSLGAMIEVYGEPENAWYEWRIIDGGRTVRDTGTE
                     GHSAFQGRQYGQAEIALRDALMFASGLPIDGDTPTDAASLEAGYAAKAKAEAARQGAGT
                     PGSA"
                     /name="hypothetical protein"
     gene            14268..15146
                     /locus_tag="H7R69_RS25760"
                     /old_locus_tag="WP7S18E04_P40160"
     CDS             14268..15146
                     /locus_tag="H7R69_RS25760"
                     /old_locus_tag="WP7S18E04_P40160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_009873352.1"
                     /translation="MALDIMAAFTNEPPELDFIWPGFLAGTVGALVAPGATGKSFFALE
                     AAMSIACSVAGGDLVGLAPAHTGRVVYLAGEDPQPALVRRVHAIGQHLNQSAREAIAEN
                     LMLEPIMGKRLNVMDEAHLRRVIDYSAGARLIVLDTLSRIHSLDENSNGDMAHLVSVLE
                     HIAATTGAAVLYLHHVNKGSARDGQTDQQQAARGASALIDNARWCGYVAKMTEQEAERL
                     SDRGFDRAPIGNERRGLFVRFGVSKQNYDATPLDRWYQRHTGGVLLPVELQEIKRESGN
                     KGGKGYDSAAY"
                     /name="helicase RepA family protein"
     gene            15127..16119
                     /gene="repC"
                     /locus_tag="H7R69_RS25765"
                     /old_locus_tag="WP7S18E04_P40170"
     CDS             15127..16119
                     /gene="repC"
                     /locus_tag="H7R69_RS25765"
                     /old_locus_tag="WP7S18E04_P40170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_009873351.1"
                     /translation="MTQQRIKPAYAKFDPAHVFDGLFVPTKGKKRGRLYVPPRRFGDSE
                     ISFQGFEQLGADDQSILLAVSAQLGIDGLMIEAKPPGEIGQQLRLALDFDNDDGRPLKT
                     KKTSLRSLLIDAGYDDPESGAALARIKESLNRMGNAQIREINHATGWDYRCNLLSSRFN
                     HKTGEIFVAVNPRLTGAVFREQHVKVSLFERNELESEAAKLLHCWLCSNIRLGRSLGNG
                     NGAHIDTLAPHVWGKAAWEEASTKVRSVRRGQLRDALDEISDRTRGLQGGMGWAIDQTS
                     SGLVLVSRPKELPFLEGEHDMRPSEYHDLMSQPPMQEPDLFDPQDWTPD"
                     /name="repC"
     gene            complement(16172..17551)
                     /locus_tag="H7R69_RS25770"
                     /old_locus_tag="WP7S18E04_P40180"
     CDS             complement(16172..17551)
                     /locus_tag="H7R69_RS25770"
                     /old_locus_tag="WP7S18E04_P40180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873366.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_009873366.1"
                     /translation="MLTGIKLRANPTSHQKLILSQWMGCARSIWNAKVEEERYYRTYAR
                     KYCTIGTYAPIDQTTSQFKSKELSPWLSECPSQILRNSAVNWYQTYQKFMSGKCGRPKR
                     KPKTDKGSIYLTREVFRFDHCDDGNVRLFIGTKTNNIGYLSFKAHGKFEIPNSLYVRKE
                     RGHYYVSFCYEQGQPDRKLSTNEEHLAFLQGATREYLEEHTMGVDRGVAIPVCAGEQTY
                     DFTHSQKKNMSKADRYIKRLQRKLARQQKGSNRRAKTKHRIAVHHAKKANIRNDFAHKT
                     SRLLVDSSAKIIVFEALRTARMTRRPKAKQDEQGRFISNKAKQKAGLNKSILNVGWHVI
                     ETYTYYKAYSSSKAVFKIPAPTTSQECAKCGHTHPDNRKTQALFVCGNCGNTDNADHNA
                     SLVIKKRAINLILDTGTVLSGDGVLRTQSDSGRGGNRKTGRAKSSTSSAQRSVKKEKLA
                     A"
                     /name="RNA-guided endonuclease TnpB family protein"
     gene            17628..18083
                     /gene="tnpA"
                     /locus_tag="H7R69_RS25775"
                     /old_locus_tag="WP7S18E04_P40190"
     CDS             17628..18083
                     /gene="tnpA"
                     /locus_tag="H7R69_RS25775"
                     /old_locus_tag="WP7S18E04_P40190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016659780.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="WP_009873365.1"
                     /translation="MYDWRTGRSCIFKNNVHLVFVTKYRRGVFTKEMLERTEAIMKETC
                     EQMDCELLEFGGEDDHIHMMVSVHPKLAISNLVSKLKGKSSYMIRREYWDRVKTMLWGN
                     HFWSPSYCVVSCGGVALDVVREYINNQNEPPSEKAMKTSQALKQRKE"
                     /name="tnpA"
     gene            complement(18106..18741)
                     /gene="tetR(C)"
                     /locus_tag="H7R69_RS25780"
                     /old_locus_tag="WP7S18E04_P40200"
     CDS             complement(18106..18741)
                     /gene="tetR(C)"
                     /locus_tag="H7R69_RS25780"
                     /old_locus_tag="WP7S18E04_P40200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(C)"
                     /protein_id="WP_009873364.1"
                     /translation="MNKLQREAVIRTALELLNDVGMEGLTTRRLAERLGVQQPALYWHF
                     KNKRALLDALAEAMLTINHTHSTPRDDDDWRSFLKGNACSFRRALLAYRDGARIHAGTR
                     PAAPQMEKADAQLRFLCDAGFSAGDATYALMAISYFTVGAVLEQQASEADAEERGEDQL
                     TTSASTMPARLQSAMKIVYEGGPDAAFERGLALIIGGLERSACAISLL"
                     /name="tetR(C)"
     gene            18834..20024
                     /gene="tet(C)"
                     /locus_tag="H7R69_RS25785"
                     /old_locus_tag="WP7S18E04_P40210"
     ARG             18835..20021
                     /name="tet(C)"
                     /gene="tet(C)"
                     /gene_name="tetracycline efflux MFS transporter Tet(C)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19928..20266
                     /locus_tag="H7R69_RS25790"
     CDS             19928..20266
                     /locus_tag="H7R69_RS25790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005291943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002310911.1"
                     /translation="MERVGMDCRRRPIPCLPPRVASRCMEPGHLDLNGSRRHLANGFTT
                     PRIGANQFLRRTVNAQTNPWQNISIASAISSSRTRRISGSVGSWPRVRMIVLLSLRTRL
                     GWRGCLTG"
                     /name="hypothetical protein"
     gene            20474..>20770
                     /locus_tag="H7R69_RS25800"
                     /old_locus_tag="WP7S18E04_P40230"
                     /pseudo=""
     CDS             20474..>20770
                     /locus_tag="H7R69_RS25800"
                     /old_locus_tag="WP7S18E04_P40230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /name="tyrosine-type recombinase/integrase"
     gene            <20980..21687
                     /locus_tag="H7R69_RS25805"
                     /old_locus_tag="WP7S18E04_P40240"
                     /pseudo=""
     CDS             <20980..21687
                     /locus_tag="H7R69_RS25805"
                     /old_locus_tag="WP7S18E04_P40240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558120.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            <21832..22026
                     /locus_tag="H7R69_RS25810"
                     /old_locus_tag="WP7S18E04_P40250"
                     /pseudo=""
     CDS             <21832..22026
                     /locus_tag="H7R69_RS25810"
                     /old_locus_tag="WP7S18E04_P40250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018229750.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            22131..23723
                     /locus_tag="H7R69_RS25815"
                     /old_locus_tag="WP7S18E04_P40260"
     CDS             22131..23723
                     /locus_tag="H7R69_RS25815"
                     /old_locus_tag="WP7S18E04_P40260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008328818.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="WP_020229221.1"
                     /translation="MPATSKPKLYNPRHPERTLLYQTVAEHYETWLDLASAGQFDGQGD
                     HRSPKPYVRQAFAKYLECGIFAHGFARARCDDCGHDFLVAFSCKGRGVCPSCTTRRMAE
                     TAAHLTDHVFPRLPVRQWVLSVPKRLRYFMQRDSVVLGMVLRIFLRVIEQTLQANSPCA
                     AHANKAALHIGAVAFIHRFGSSLNEHVHFHVCVVDGMFEAVAGEASEQGTRTTAISVMF
                     HPAIGIDPEAVTQAQASLRRRILRAFVGRGLLEGFEAQEMLGYKHSGFSVDTSVCIAAQ
                     DRAGLERLLRYCARPPFALDRLRKAGSELIYRCAKQHSEPGSDRRDQRKAKRGVRADEL
                     HLTPLELIDRLAALVPPPRAHRHRYYGVLAPNSPLRAAAVALGAGQTAGAGTGTAQPEP
                     GGVTAAVDAMGVATVGGPSQPEPTQPALPKRSAHILWAVLIARIYEVLPLLCPLCGGQM
                     RIIAFITYSADLRHILEHIGVETEPPRIAPARGPPLWDGCDVPMGDGVEVEPDWGEAAQ
                     PAPDFEVDQRVSW"
                     /name="IS91 family transposase"
     gene            23780..24403
                     /locus_tag="H7R69_RS25820"
     CDS             23780..24403
                     /locus_tag="H7R69_RS25820"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: protein motif:HMM:NF013670.3"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]; GO:0008745 - N-acetylmuramoyl-L-alanine amidase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_182930711.1"
                     /translation="MCKPKNLGLLALIKRSGRLSLKACDAQNLGHNRPPVVGFPIRKLK
                     ELLTKKGAKVLMTREIDDSLDDHIPNNGSRHREDLNSRVKIVNNSKVDILLSIHVNHNK
                     NANKIGPIIFYNTSSEESKYFANHIQEYLNNLSSYKEIDIGTKHKATPGDYYLLRNISP
                     PGVIIEMGFISNESDRRLLLDNKHLDEIVELITKGIIDYFNADR"
                     /name="N-acetylmuramoyl-L-alanine amidase"
     gene            24797..25336
                     /locus_tag="H7R69_RS25825"
                     /old_locus_tag="WP7S18E04_P40270"
     CDS             24797..25336
                     /locus_tag="H7R69_RS25825"
                     /old_locus_tag="WP7S18E04_P40270"
                     /inference="COORDINATES: protein motif:HMM:NF012792.3"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_070085966.1"
                     /translation="MQIINMTQVNKTQLIQAAQILTDSIPIGWPTLHDAMDEIKERLIP
                     ENTLLAAIENDIVIGWGGILAPMYNGNVFELHPLAVRSDKRNLGIGRTIVTALEDEARK
                     QGGLTIHLGADDEGGDGETSFANVDLYDDLPGKINNFNAGTHQSGFYLKLGYKIIGVMP
                     DANGIGKPDIYFGKGL"
                     /name="GNAT family N-acetyltransferase"
     ARG             complement(1728..2242)
                     /name="APH(6)-Id"
                     /gene="APH(6)-Id"
                     /gene_name="APH(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.42"
                     /coverage="61.51"
     Typing          14269..15146
                     /name="IncQ2"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          10631..13299
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.888"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gatctagtaa atctgctatt gtcattccaa tagctcccgc aaatccccca taccatccac
       61 ctagaagtaa agcagctaat acgccatcgg tgaggttcaa ttgccggaag tgattctggc
      121 cgttgacgcc caggtgcgct ttagctggat catgctcgga cgtgagccgc gctctaccga
      181 cgagctgctg atggtctatg ccggcatcat ggcccacggc accagtctga ctgcggtcga
      241 atgcgcgcgc atgattccgc aattgtctgc caccagcatt cgccaggcca tgcgctgggc
      301 gcgggacgaa cggcgtctga gccaggcctg ccaggctgtg ctggaattca tgcagcgaca
      361 cccgattgcc gccacctggg ggcggtccga tttggcatct tctgacatga tgagcatgga
      421 gaccaccaaa cgggtgtggc aagcccggct tgatcctcgg cgcaacacac cttccattgg
      481 aatctactcc catgtaaaag accggtgggg catcttccat gcgcagccct ttgtgctcaa
      541 tgagcgccag gcgggcgtgg ccattgaagg tgtcatccgc caagaaaagc tggagaccag
      601 ccagcttgct gtggataccc atggctacac ggggtttgag gtccaaccgt acgaaaacgt
      661 acggtaagag gaaaattatc gtctgaaaaa tcgattaggc tagaaagtcc gttaagtgcc
      721 aattttcgat taaaaagaca ccgttttgat ggcgttttcc aatgtacatt atgtttcgat
      781 atatcagaca gttacttcac taacgtacgt tttcgttcta ttggccttca gaccccatat
      841 ctaatcgata ggtgaaccat cctgcacaat tctgatgatt ttcatgaatc ctgtcgtttt
      901 taacataatg ggtattaagt gtagtgtgtt tgtctatcaa taagagattt atctaattta
      961 attcaagccc ccggcgcagg tggtaaccac ccccggcgca ggtggtaacc acccccggcg
     1021 caggtggtaa ccacccccgg cgcaggtggt aacctgacaa gccacaaaaa cgcccgcaaa
     1081 cccttgtcag tactgagttt tcgcgttttt ccaaaattcc ggtctaagaa gttctaaaga
     1141 acttctacca tgcgcggctt tcagccgccg ctttaggcgt cgtctgaagc cttgccttcg
     1201 ggcttcgccc tgcgcgggct aaagcccttg cagacacacc cccgcccccg ccccgccgct
     1261 acccccttcc ttgcaggcga aaacgcctct actggctttc tagggcctct gccggggctg
     1321 cggtgagcgt atccagcaga tcgactatcc gcctcatggc ttctaaccac gcttcgtgca
     1381 tccagaatgg ggctatttcg ccgtgctgga gtgtgcaaag cggattgaga acccggcgcg
     1441 ggttcttcca tgtctcgacg gaaagcacca gcccgtccgc atggatggaa aagactggta
     1501 gcgctttcgg ctggcccttc ttcttgcctt gcgtttcggt tggcttgagg tcgtcccaaa
     1561 cgccttgcac ggttttgttc agttcgtcga tgaagcgttc cggcatggtt ttcaagagtt
     1621 ggggtcgttt gcgggagagg gcgaaatcct acgctaaggc tttggccaac gatattctcc
     1681 ggtaagattg atgtgttccg aggggatagg agaagtcgct tgatatctag tatgacgtct
     1741 gtcgcacctg cttgatcgcg gccgcgatag ctagatcgcg ttgctcctct tctccatccg
     1801 cgttccaagc tgcggaaagg cacccataag cgtacgcctg gtcgagcagg cgacgcggat
     1861 cgacgtccag cgcacgagag aatgcgtccg ccatctgtgc aatgcgtctg ggatcgagac
     1921 aaaggtcgtc tctgtcagcc ggatcgtaga acatattggc ggcgccaaag cccacttcac
     1981 cgaccagacc gacgggatct atcaccagcc agccgcgact ggagaacatg atgttttcat
     2041 gatgcagatc gccatgtagc ccacgcagtt ccgaggcatt gctcatcatt tgatcggcta
     2101 taatcgccgc gtggacgtag tcagtttgac aacctgcgtt ttgatcatcg cgcgcccgct
     2161 gaaacaaagc tgcaaagcga tcccggatcg ggagaagggc agaaggcagg ggttcctcag
     2221 atgcggcata cagcttcgcc attagttccg ctgcaatttg gggtcggttc cggctgaggg
     2281 cgaaatgaca ccctaagcgt tagctctgtg tcgttgcacg atgtcagcga cggtattctt
     2341 gctgataccg agctcgcgtg cgatccagcg atagctgcgt ccctcggccc tcatcgcaac
     2401 caccttaggc aaaagtcggt ctgattttgg tcgcactccg gcctgacgac caagcctctt
     2461 accacgtgcc ttcgcaacag caaggcctga cttgacccgc tcgctgatga gatcccgctc
     2521 aaactccgca atgccggaaa gaaacgtcgc cagcattcgt ccatacggcg acgaaagatc
     2581 gaacgccatt ccattcatgg ctatcacgga aaccttccag ttctccagtt cacgtagcgt
     2641 attgagcaga tcgagcgtcg agcgccccca ccgggaaagc tcagtgacca ggattgcatc
     2701 aatttgtctg gactgggcaa gcgccaggac tttctttcgc tcggcccggt cgagtttagt
     2761 tcctgaacct gtttccttaa atattcccac cacgtcgtag ccggcacggc cggcgaaggc
     2821 tcgcagatca aattcctggc gttcacaaga ctgatccgct gttgaaaccc ggcagtaaat
     2881 ggcggcacga tgtcccaatt gaaccctcct ggatttttgt atcggaacgc cctgatttat
     2941 atgggctggc tgttgtccaa aacagactat acttcaaaag ggacgaattt gtatgtcacg
     3001 acgccatatt ttcaccgaac ggcagcgagc agcgctgttc gatctgccca cggacgaact
     3061 gtcgctactg aagttctaca cgctgggcga tgatgacctg gaaaacatta ggcagcgccg
     3121 cagaccggaa aacaggattg gctttgccct gcaactttgt gccttacgat atccgggccg
     3181 tgcactggct cctggtgaga tgatcccgcg tgaagtcctt tccttcgtcg gtgctcagct
     3241 tggagttccg gctgatgcgc ttctcactta tgccacacgg cgccaaaccc gtcagcagca
     3301 catggacacg ctgcgcgaaa tttacggcta caagaccttc acgggccgtg gtgcccgtga
     3361 tctgcgggag tggactttcg gccaggccga agatgccaga tcaaacgagg atcttgctca
     3421 tcgttttatt gtgcggtgtc gggaaacttc caccattctg cccgcagtat cgacaatcga
     3481 gcgcttgtgc gcggatgctc tggtcgccgc tgagcggcgg attgaaacgc ggattgcgga
     3541 aaatttaaca gcggatgttc gcgatcacct ggacaaactt ctgagtgaaa tgctcgccgg
     3601 caatatcagt cgtttcatct ggcttcgcaa cttcgaggtt ggtaacaact cggctgctgc
     3661 taaccgtttg ctcgacaggc tcgaatttct gcgtaccctg aatatcaatc atagtgcttt
     3721 ggccagcata cctgcccatc gcattgcccg gctgcgtcgg cagggtgaac gctacttcac
     3781 cgacggtttg cgtgacatca cttcggaccg ccgctgggcg atccttgccg tctgtgttgt
     3841 ggagtgggaa gcggcgattg ctgatgccat agtcgaaacc catgacagga tcgtaggaaa
     3901 aacctggcgg gaagcgaagc gccagcatga cgaaacaatt tccggctcta aagccacact
     3961 cacggatacg atccgtacct tcaccgcgct gggagcttcg ttgcttgagg cccgcagtga
     4021 cggaaccccg ctggagatgg ctgtcgccag ttcggttgca tgggaccggc tcgctcaact
     4081 ggtagcgaca gggactcaac tcagcaacac gctagccgat gagcctcttg catatgtcgg
     4141 gcagggatac catcgctttc gtcgttatgc gccccgcatg ttgcgctgtc tgaagctcga
     4201 agccgcgccg gtcgccggac cattggtagc agcagctttg tcgatcggag agatgaaagg
     4261 tgttgcatcg ccagaaaggc gtttcctgcg gcccagctcc aaatggaacc gtcatttacg
     4321 agctcaggaa aaaggagata cccgtctttg ggaagtggcg gtactctttc acctccggga
     4381 tgcttttcgt tccggagatg tctggctcgc tcattcgcgc cgctatggtg acctcaagca
     4441 ggtactggtg ccgatgatcg cggcgcagga aaatgcaaaa ctggccgtgc cttccaaccc
     4501 acaggattgg ctggcagaca gaaaggcgcg actcacgatc gctcttaagc ggctggcccg
     4561 ggctgcccgt aacggcacta ttccgcacgg tagcatagaa gatggaacgt tgcggatcga
     4621 caggttgaca gcagacgtgc cggatggtgc cgaggcactc atactggatc tgtatcgccg
     4681 aatgccgtcc gttcggatta ccgacatgct gcttgaagtt gatgcagccc ttggtttcac
     4741 agatgcgttt acccatctga gaaccggggc tccatgtcgc gaccggatcg gtctgctcaa
     4801 cgtcctgctc gctgaagggc tcaatctggg cctgcgtaag atggcggaag ctacaaacac
     4861 gcatgattac tggcagctct cacgccttgc ccgctggcat gttgaaagcg aagccatgaa
     4921 ccaggcattg gcaattgtgg tggccgcgca gggtaaactg ccgatgtcac gcgtctgggg
     4981 gatgggcacg tcagcatcga gcgatggtca gtttttcccg acagcgcggc atggcgaagc
     5041 catgaacatg gtcaatgcca aatatggttc tgttcccggc ctcaaagcgt atactcacgt
     5101 aagcgaccag ttcgcgccat tcgcttgtca gtcgatcccg gcgaccgtga gcgaggcacc
     5161 gtatattctc gatggactac tgatgaacga ggtcggtcgc catgttcgcg aacagtatgc
     5221 cgatacagca ggattcaccg accatttgtt cggagccagt agcctgctcg gctacaatct
     5281 cgttctgcga atcagggatc tgccatcgaa gcggttgtac gtatttaatc ccgatacgac
     5341 ccccagggag ttacgcaagt tggtaggtgg aaaagcccgg gaggatctta tcgttgcgaa
     5401 ctggcctgat attttccgtt gtgccgcgac gatgaccgct ggcaaaatca ggcccagcca
     5461 actcctgcgc aagctcgctt cttacccacg acaaaacaac cttgcagttg cgcttcgtga
     5521 agttggtcgt attgaacgga cccttttcat tattgagtgg atcctggata cggacatgca
     5581 gcggcgtgct cagatcggtc ttaacaaggg agaggcccac catgcgctca aaaatgcgct
     5641 ccgtatcggg aggcaggggg aaattcgcga tcgcacgaca gaggggcagc actaccgaat
     5701 cgctgggctc aatttattga ctgcggtgat catttactgg aataccgtcc atcttggtca
     5761 tgccgtcacg gagcggcgga acgaagggtt ggatgttccc cctgaatttc ttccccacat
     5821 atccccattg ggctgggcgc acattctact gactggcgaa tatctttggc ccaaggaacc
     5881 gaaagcttag ggtgtcattt cgccctcagc cggaaccgac ccctatttgc catgcaaagg
     5941 tcgcagacga agcgggggtg gtgcgtgaca ccctgaaatc cttcgccgag atcgggggcg
     6001 ccctggtcga tgcacaggat gatggccagc cgctgggcga tgtcatcgcg agtgggtcag
     6061 ggtgggacgg cttaaaaacc cttgttgcaa tggcaaccag gctgaccgcc accatggccg
     6121 acgatccgct caatcatgtg ctcgacggtt atcaccgctt ccgccgatac gctccacgca
     6181 tgttgcgcct gctcgatctg cgagctgcgc ccgttgcact gccgcttctg gaagctgtga
     6241 cggcccttcg taccggtttg aacgatgccg cgatgaccag cttcttgcgg cccagctcga
     6301 aatggcatcg ccaccttcgg gcccagaggg ctggcgacgc tcgcctatgg gagatcgcgg
     6361 tgctgttcca tctgcgcgat gcgttccgct ccggagatgt ctggcttact aggtcccggc
     6421 gctatggcga tctgaaacac gcactcgttc cggcacaagc catcgcggaa ggcggtcgtc
     6481 tcgctgtgcc attgcggccg gaggaatggc tggcagaccg gcaagctcgc ctcgacatgc
     6541 ggttgcgcga gcttggccgt gccgctcgcg caggcacgat cccgggcggg tcgattgaga
     6601 acggcgttct gcatatcgag aaactcgaag ccgccgcgcc gacaggcgcc gaagatctgg
     6661 tgctcgatct ctacaagcag atcccgccca cgcgcatcac cgatctcctg ctggaggtgg
     6721 atgcggcgac cggcttcacc gaagcgttca cccatctgcg cacaggagca ccctgcgctg
     6781 accggatcgg gctaatgaac gttatcttgg cggaagggat caacctcggc ttgcgcaaaa
     6841 tggcggatgc gacaaacacc cacaccttct gggaattgat ccgcattgga cggtggcatg
     6901 tcgagggcga agcctatgac cgggcgctgg ccatggtggt cgaggcacag gcagcgttac
     6961 ccatggcccg gttctggggc atgggcacgt cggcttcgag cgacggacag ttcttcgtcg
     7021 ctacagagca aggtgaggcc atgaacctgg tcaacgcgaa atatggcaat accccgggcc
     7081 tgaaagctta tagccacgtc tccgaccaat atgcgccgtt cgcaacccag gtaattcctg
     7141 caacggcaag cgaagcgcct tacatcctcg atggcctgct gatgaacgat gctggacgcc
     7201 atatccgcga gcagttcacc gacacgggcg gcttcaccga tcacgtcttt gccgcatgtg
     7261 ccattctcgg ctaccggttc gctccgcgca tccgcgacct gccatccaaa cggctctacg
     7321 cgttcaatcc gtcggccgcc ccggcgcacc tgcgagcgtt gatcggcgga aaggtcaacc
     7381 aagccatgat cgagcgcaat tggcccgaca tcctgcgcat cgccaccacc attgctgccg
     7441 ggaccgtcgc gccaagccag attctgcgga aactcgcctc ctatccgcgg cagaacgagc
     7501 tcgcgacagc cctgcgggaa gtcggtcgcg tcgagcgcac cctgttcatg atcgactgga
     7561 ttctggatgc cgaactccaa cggcgtgccc agatcgggct caacaaaggc gaagctcatc
     7621 atgcgctgaa gcgggcaatc agcttccacc gccgcggtga aatccgcgac cgttccgccg
     7681 aaggccagca ttaccgcatc gccggcatga atctgctcgc cgccatcatc atcttctgga
     7741 acaccatgaa gctcggcgag gtcgttgcaa accagaaacg cgatggaaag ctgctatcgc
     7801 ccgatctctt ggcccatgtt tcgccgctcg gatgggaaca catcaatctc accggagaat
     7861 atcgctggcc aaagccttag cgtaggattc cgccccctcc cgcaaacgac cccgagttcg
     7921 gcagtgattg cgttcgcgtc ctcaaattgc tttcttgctt cggcttcctt tttccgtcgt
     7981 ttttgccgct cctgttcgta ttcgtctaag gtttgcctgt gtctgcgctg tgcttcagct
     8041 tccgcttctt cagcttgcct tcgtgcttcc tctttggctt tctgtcggtg tgcttcaccc
     8101 tctgctgtga gtgctggttt taccagttcg ccagacttgg cctcgatggt gatcgaaagc
     8161 ggttcgccgc gatggtctac cagatcgaac ggcagaccat cagcatcgaa ggcggttagg
     8221 tagagattgg ccccatagac cttgtgcccc ggcctcacag cttcgtattt ttctgctgct
     8281 gcgtgcagtg cttccgctag gcgttctgcc gtgatttctc ctttgatctt gattctcatg
     8341 gcaacctcca tccgtaggtg ccatccgatg cgggcttgac gtagcacacg cctttttcga
     8401 cgtaccaccc cggcctatcg cacttcgcca agctggcgag gcttcccgtt tgcgcgaagc
     8461 ggtaggccaa gcgcccctct ggcgtgttgg cccatgccgc cgccgctttc tcgtccttgg
     8521 cttcggtgta tcccgcgccg tatccggcct gatagcccga atccttgccg ctgctgtgca
     8581 tgtaccagcc gaacaggccg acgcacagga aggccaccgc gatgcagccc gccgcccact
     8641 gccacatctg ctttgccgat gtgttgtgcg cgacctcttg cgctgctgct gctaccgctt
     8701 gcgccaaatc cgccttggct gcttccgctg atgctttcac ggttgcatcc gccgttacct
     8761 tgaaattgac caaggtatct ttggccgctt gtgctatcgc ttgcgggaac ttctcatact
     8821 ggccttggta gtgttgcaag gccatgagca ccagccacag cgcatcattg tttttcaggc
     8881 cgagcgcatc ccgaacccgg taaagacttt gccgctccgc gtcactaggt tgcctgccga
     8941 gcagctttgc aaagctgtcg tctaggtcac tcatggacta cggcctccaa tacctttttg
     9001 gcctcgttgc gccaccgcgt aagctccgca cggttgccaa tgggcagttc cttgagtgct
     9061 accgcaatgc tcatgcgctt gctgtaaatg tcatcgctca cacggtcggc catgtccggg
     9121 aatgtcaccg atttcccgcc gcgttcctct accgccgtgc gcagcttgga gccgttgtaa
     9181 agctcgaact tcttttcttc cccgaagtgt ccattgcgta ccacatgaac atccgcattc
     9241 ggaattgcgt ccatgtattc ctttagcagt tcgaggctat cccgttggcg gttaatcacc
     9301 cacagcgtga ccagcttgcg cttgagttct tcaagcgtgc tattcagtgt ttcaccgtag
     9361 gcgctcacgc ccttgttatt ccgtgctgcc gtgttgatta ccacgacgct atccggcttg
     9421 ctatcgcaca ggttcactag ctgaatccat ccgtccgcct catccagatt gataagctcc
     9481 gtttccgtgc tttctttata ggctttccat acgtccgggt tagaggtgtc agactcaatc
     9541 agcaagacgc tttcgccgcg ctcttgcagg taatcaaccg ttgccatcgt aacaagcgac
     9601 ttgccaacgc cgcccttgct gccaccgatc aggtaaatgc ttttcgccat gttgcttact
     9661 ccttaaatgt cgtcgctgtc aggtttcggg gtgaatgtcg ccttcgatgt atccgcaggc
     9721 ttcttatcgg cggggagggg cgggggtgtg tctcccggtg cttgcaccgg ggcttttttc
     9781 gctggctttg ctctctgcaa gtagctcttg agcgttgggg ttgcgatgct cagaccttcg
     9841 ccgcgcagcg tctcggaaat ctggtcaagc gtgtatccac gcttttgcaa agcggcaatc
     9901 tctttggata gcacgcgcac ggcctcttgc ttgctgtgct cctgcttctt cttttcgact
     9961 ggcggcatct cacgaagctt tgaagcgata gcctctagct gctctgttgt gtatttcatt
    10021 ctgctaactc ctttgctcac tggttgcgga gttgacagca tagcgccttt tatgcttgtt
    10081 gcaaagtgcg tcccgtgcac ctaaactgct gatatgatag tagagtggtt gagcaataca
    10141 ggatgcggat tgtcatacac atgctacgca tgttcctgcc aatccccgcc tgcccattcg
    10201 gcgcttcgct tctcacggtc tggctcatcc tgcaaggggc aagccccttg accccggaca
    10261 gtgcggcgct ttcgcttctt actgtccaag acacaccccg cccccgcccc cggcgagaag
    10321 gagacatgat gccatttgaa acgcaggggc cggaaccgct ggacgccgtt atcaatgtgc
    10381 ggctgaccgc agcggagaag gccagattga aagaggacgc cgaccttgcc gggttgagca
    10441 tgtccgagct tgtccgccgc cgctacttcg gcaggccgat cattgccaac gccgacgccg
    10501 tgatgctcaa ggagctgcgg cgcatcggtg gattgctgaa gcacatccac aacgagagcg
    10561 gaggcgttta cagcaaggaa acagccgggg cgcttgttgc gctcaaggac tacttcagga
    10621 agctaaacga tgatcgttaa gaaggttccg aatccgaaga agtccgcgag caaggcgcag
    10681 cgcatcggcc agcttaccag ctatgtccgt tcgccggagt cggagagtcc gcaggaaaag
    10741 tgtctgtatg ccggggcgcg gggtttcatg atggacgacc ccaagagcca gacggcagag
    10801 atgattgcac tctcacaaga agccgtgcgc agcaaggaca ccatcaatca ctacgtcttg
    10861 agttggcgcg aaggcgaaca gccaagcccg gagcaagtag aggaagcggt tagcatcttc
    10921 atggatgagc ttgggtggaa agaccaccaa gccatctatg gccttcattc cgacacggac
    10981 aatatccacc tgcacatcgt catcaatcgg gtgcatcccg aaacgctcaa gattgttgag
    11041 aagaaccgtg gatttgatat tgaactggca cacaaagcca ttgcacggat tgagcacgcc
    11101 caaggctggc agcgtgagca aaacgggcgc tatcaggtgt tggagaacgg ggagctaggc
    11161 cgagcgccat acgacccgga aaagccacgc cagcccgacc agaagaagcg ggacatggag
    11221 aaccgcaccg gggagaagtc agcccaccgc atcgccatcg aggacggcgc agccatcatc
    11281 aagcaggcgc agacgtggga gcagttgcac cgcgagttag cagccaaggg gatgcgctac
    11341 gaaaagaccg gcagcggggc gaccgtgttt gtcggggatg ttggcgtgaa ggccagcgat
    11401 gtagaccgca acgccagcct tgccaagatg cagaagcggc taggtgaata ccagccagcg
    11461 ccgcagcgtc agcaggtagc gccgcgcgag ccggagccga tcaagccaga cgtgccggga
    11521 tggaaggact acatcagcgg gcgcaaggca cactacgccg agaagaacgc ggacaagctg
    11581 gcacaggaca agcggcagga gcaggagcgc aagcaacttg ccgagcagca gaaggcccgc
    11641 cgcgatgaac tcatgcgcgg aaactggaaa ggcaagggcg aagtgctcaa cgccatgcgc
    11701 agcgtgattg ccgccgagca ggccgcagag aaagcggcct tgaaggagaa gcaccagaag
    11761 gagcgcgagc agcaccggca gcggttccga ccctatcccg acctggagca gtggcagcgg
    11821 atgcagaaaa gcccggagct tgccgagcag tggcgacacc gggccagcga gccgcagcgc
    11881 atcgagggcg accgcagcga gccgccgacg ccgcgagaca ttcgcgccta tcagcctgaa
    11941 atcgtgggcc agcaggtgca ttacagccgg aaggaagaag cggggcgggg cgggggtgtg
    12001 tctttcgtgg acaagggcaa aagcatcgat attcacgact ggcgcaaccg ggacagcacg
    12061 cttgccgcgt tacagctatc ggcgcagaag tggggcagct tcaccgtgat ggggaacgac
    12121 gaatacaagg ccatgtgcgg gaagttagca gcagagcacg gcttcaagat cacaaatcca
    12181 gagcttcagg agagcatcca gcaggagcgg cagcggatac agcaggaaag ggtgcaggcg
    12241 atgaaatcgg agcagctaaa gcagttcgag cggtacgcgg aagcggtagg cgcagagcgt
    12301 taccgggtaa cgtctatcaa gatgcgcgag gacggcagca agcaaacctt catcctcgac
    12361 aagaaggacg gcatcacgcg gggcttcaca ccgcaggaga tcgagcagcg cacgccggag
    12421 atgcagcgcc tacagcgccg gggcgaaaac ctctactaca cgccgctatc ggacaagaag
    12481 catcacatcc tcatcgacga catgaaccgg gagaagctgg agcggcttat ccgcgacggc
    12541 taccagcccg ccgccgtgct tgaatccagc cccggcaact atcaggccat catcaccgtg
    12601 ccgaagctgg ggacggccca cgataaggac gtgggcaacc ggctgagcga tgccctgaac
    12661 cgtgaatacg gcgacccgaa gctatcggga gccatccacc cgcaccgtgc acccggctac
    12721 gagaaccgca agcccaagca ccagcgggag gacggcagct atcccgaggt gcgcttgctc
    12781 aaggccgagc gccgggagtg catcaaggcg ctggccttgt ccagccagat cgacgccgag
    12841 tatcagcggc aagcggcctt gaaggcgcag cagcccgagc gcagcaaagc caagcccgcc
    12901 ttggagcttg cagcggccag cggcagcgcg atcgacgcct accagcggca ttatcgcgac
    12961 gtgctcaagc ggcagcgtgg cggcgaggtg gacttgtccc gcttggattc catgattgcc
    13021 gtgcgtatgc gcgtcaccgg ccacgatcaa gccgccatcg agggcgctat ccgccagtgc
    13081 gccccggcca cccggcagaa ggacgagggc cgcgactgga acgactacgc gcagcgcacc
    13141 gcccgctatg cctacagcgc cgcaggcgac cgccaagccg ccgagcttgg gaagtaccgc
    13201 cagcagtggg agaagctgga agggcgcgag cctgtacgcc agcaggagca ggccaaggcg
    13261 cagaagatcg agcgcgataa ctcgccgggg atgagtcttt aaatacctgt tgcatgtaac
    13321 ttgcgaggtg cgtacaatgt tgcatgtaac ttaattggag gcttggaaat ggcaacagca
    13381 cacgttaatc agcgggttca gaagcatcgc gatgcattac gcatggcggg gcttcgtccg
    13441 gttcaaatct gggtgccgga tacgcgccgc cccgacttcg cggaggagtg ccgccgccaa
    13501 tgcctgcttg tggctcaggc cgacagcgcc gacaccgcca tgcagcagtt catggatgaa
    13561 gccttggcag acgtggacgg ctggacggaa tgatgcgcgg cgaccttgtg accatcgcca
    13621 tgcagggcga ctttggcaag ccacggcctg cgcttgtggt tcaggccaac cagttcagcg
    13681 agcacggcag cgttaccgtg ctgcctgtca ccagcacact taatgccgcg ccgttgctgc
    13741 gcgtcacggt tcagccgagc gcagagaacg gtttgcagaa gccatcgcag gtgatggtcg
    13801 acaaggcgat gacggtgctg cgcagcaagg tagggccagc tttcgggcgc atcgacgcgg
    13861 acgcactgct tgaggttgag cgttgcttgg ccgtgttctt ggggattgcg aaatgaaaac
    13921 gatctacacc attcccgccc cggattcctt gggcgcgatg atcgaggtct acggcgagcc
    13981 ggaaaacgct tggtacgagt ggcgcatcat cgacggcggg cgcaccgtgc gggacaccgg
    14041 cacggaaggc cacagcgcct ttcagggacg ccagtacggg caagcagaga ttgccctacg
    14101 tgatgcgctc atgttcgctt ctggcctgcc catcgacggc gacacgccga ccgatgccgc
    14161 cagtctggaa gcgggctatg ccgccaaggc gaaggcagaa gcggcgcggc agggtgcggg
    14221 aacacccggc agcgcctaac cataaccgtt ctacacagga gaacagcatg gctttagaca
    14281 ttatggcggc cttcaccaat gagccgccag aacttgattt catctggccc ggattcttgg
    14341 ccggaaccgt gggcgcactt gttgcacctg gcgcaactgg caagagcttt tttgctcttg
    14401 aagcggccat gtcaatcgct tgcagtgtgg caggcggcga ccttgtagga ctggccccgg
    14461 cgcacaccgg gcgcgtggtc tatctcgctg gcgaagatcc acagcccgcc cttgtgcggc
    14521 gtgtccacgc catcggccag cacctcaacc agtcggcccg cgaagccatc gctgagaacc
    14581 tgatgcttga gccgatcatg ggcaagcggt tgaacgtgat ggacgaggcg cacttgcgcc
    14641 gcgtcatcga ctacagcgca ggggcgcggc tgattgtgct ggacacattg agccgcattc
    14701 acagcctcga cgagaacagc aacggcgaca tggcccacct tgtttccgtg ttggaacaca
    14761 tcgcggcaac caccggggcg gctgtcctgt acctgcacca cgtcaacaag ggcagcgccc
    14821 gcgacggcca gaccgaccag cagcaggcag cgcggggcgc gtctgccctg atcgacaacg
    14881 ccagatggtg cggctatgtc gccaagatga cggagcagga agccgagcgc ctgagcgacc
    14941 ggggctttga tcgtgcgccc atcggcaacg agcggcgcgg cctttttgtc cgctttggcg
    15001 tgagtaagca gaactacgac gcgaccccgc tagaccgctg gtatcagcga cacaccggcg
    15061 gggtgttgct gccggtagag ctacaggaga tcaagcgtga gagcggcaac aaggggggca
    15121 agggctatga ctcagcagcg tattaaaccg gcctatgcca aattcgatcc cgctcatgtg
    15181 tttgacgggc ttttcgtccc cacgaagggg aagaagcgcg ggcgactgta tgtgccgccg
    15241 cgccgcttcg gcgatagtga aatcagcttt caagggttcg agcagcttgg agctgatgac
    15301 caatcaatct tgcttgcagt aagcgcccag cttggcattg acggcttgat gatcgaggca
    15361 aaaccacccg gcgaaatagg ccagcaattg cgccttgctt tggactttga caacgatgat
    15421 ggaaggccgc tgaaaaccaa gaaaaccagt ttgcgcagcc tgctgattga tgctggatat
    15481 gacgacccag aaagcggggc ggcacttgcc agaatcaagg aaagcctgaa ccgaatgggt
    15541 aacgcgcaga tacgggaaat caatcacgct accggctggg attaccgctg caatctcctt
    15601 tcgagtcggt tcaatcacaa gactggggaa atctttgttg ccgtcaatcc gcgcctgacc
    15661 ggggcggttt ttcgagagca acacgtcaag gtttcgcttt tcgagcgcaa cgagctggag
    15721 agtgaagccg ccaagctgct gcactgttgg ctgtgctcaa acatccggct tggccgttcg
    15781 cttggcaatg gcaacggggc gcacatcgac acgctagcgc cccacgtatg gggcaaggcg
    15841 gcgtgggaag aagcatcaac gaaggttcga tcagtcaggc ggggtcaact acgcgatgct
    15901 ttagacgaaa tctcagaccg cacacgcgga ctgcaaggcg gtatgggatg ggccatcgac
    15961 cagaccagca gcgggcttgt gctggtaagt cgtcccaagg aactgccgtt ccttgagggt
    16021 gagcacgaca tgcgccccag cgaataccac gacctcatga gccagccgcc aatgcaagaa
    16081 ccagatttgt tcgacccgca ggactggacg ccggactgag ccgcacctgg tgaactactc
    16141 gctgctaaag cggtcgagct tccaaactaa cctaagcggc cagcttttct tttttgacgc
    16201 ttcgttgagc actgctggtt gagcttttgg ctcggccagt cttacgattg cctccacgtc
    16261 cactatccga ctgagttcgc agaaccccat cgccagataa caccgttcca gtgtccaaaa
    16321 ttaagttaat tgcccgcttc ttgataacca gtgatgcatt gtgatctgca ttgtcagtat
    16381 ttccacaatt accgcaaaca aacagggctt gtgttttgcg attgtcggga tgagtgtgac
    16441 cgcattttgc gcactcctga ctggttgttg gtgcgggtat tttaaatacc gctttgctgg
    16501 atgaataagc cttgtagtag gtgtaagtct cgatcacatg ccagcccaca ttaagaatag
    16561 acttattcag tcctgctttc tgcttggctt tatttgatat gaatcgacct tgttcatcct
    16621 gttttgcttt cggccttctc gtcatccttg cggttcgtaa cgcctcaaac acaatgattt
    16681 tggcgctgct atcaaccaat aaccgactgg tcttatgcgc aaaatcattt cgtatgttag
    16741 cctttttagc atgatgaacc gcaattcgat gcttggtctt ggctctgcgg ttagagcctt
    16801 tttgctgcct tgccagtttg cgctgcaatc gcttgatata gcggtctgct ttgctcatgt
    16861 tctttttctg gctatgggtg aaatcatagg tttgttcgcc agcacaaacg gggatcgcca
    16921 cgcctcggtc aacacccatg gtgtgctctt ccagatattc tctggtcgcc ccttgcagaa
    16981 aagctaagtg ctcttcattg gtacttagtt tgcgatcagg ctgtccttgc tcatagcaga
    17041 atgacacata atagtggccg cgctcttttc tcacataaag cgagtttggg atctcaaatt
    17101 tgccatgtgc cttaaaggac agataaccga tattgttggt ctttgtccca ataaacaggc
    17161 gcacgttgcc gtcatcgcaa tggtcgaaac ggaacacttc acgggtaaga taaatgcttc
    17221 ctttgtccgt tttaggtttt cgctttggcc tgccgcattt cccgctcatg aatttctgat
    17281 aagtttgata ccagttaacc gcgctattac gcaagatttg actagggcat tcacttagcc
    17341 acggagaaag ctctttggat ttgaattgtg aagtggtctg gtcgatgggc gcgtaagttc
    17401 cgatggtgca atatttacgg gcataggttc ggtaataacg ctcttcttct accttggcat
    17461 tccagatact acgagcgcac cccatccact gactcaagat cagtttttgg tgagatgtcg
    17521 ggttagcgcg tagcttgatg ccagttaaca tgatgtccgt ttatttgcta tttacacctg
    17581 aaattattac acttacttaa actttgtcaa tctagcatgt ggttataatg tacgattgga
    17641 gaacaggtag aagctgcatt tttaaaaaca acgttcatct agtctttgtt acaaagtatc
    17701 gtcgtggtgt ttttaccaaa gaaatgcttg aacggactga ggcaataatg aaagagactt
    17761 gtgagcagat ggattgtgag ctactggagt ttggtggaga ggacgatcac atccatatga
    17821 tggtgtccgt acatccaaaa ttggcaatct caaatttagt cagcaagtta aaaggtaaat
    17881 cgtcttacat gatccggcga gagtattggg acagggtaaa aacaatgctt tggggcaacc
    17941 atttctggtc gccaagctac tgtgtggttt cttgcggagg ggttgccctc gatgttgttc
    18001 gggagtacat caacaaccag aacgaaccgc ccagcgaaaa agccatgaag acatcacaag
    18061 cgttgaagca aagaaaagag tagaaaccac ttgcttgact cgcccctaaa ggagcgagat
    18121 tgcgcaagca ctccgttcaa gaccgccgat gatgagagcc aggcctcgct cgaatgccgc
    18181 gtccggaccg ccttcgtaga cgattttcat cgcgctctgt aggcgcgccg gcatcgtaga
    18241 cgctgaggtg gtcaactgat cttcgccccg ctcctcggcg tctgcctcgc tagcttgctg
    18301 ctcaagaaca gcgccgacgg tgaagtagct gattgccatc aacgcatagg tcgcgtcacc
    18361 tgccgaaaag ccagcatcgc aaaggaagcg aagctgcgcg tcggcttttt ccatctgcgg
    18421 cgcggctggc cgcgtcccgg catgaatacg cgcgccatcg cgataagcga gcaacgcccg
    18481 tcgaaaactg catgcattgc ccttcaggaa cgaacgccag tcgtcgtcat cccttggcgt
    18541 cgaatgcgtg tgatttatcg tcagcatggc ttcggcaagt gcgtcgagca acgcacgctt
    18601 gttcttgaaa tgccagtaga gcgctggctg ttgcaccccg aggcgctcag ccagtcggcg
    18661 cgtcgttaga ccttccatgc ccacgtcgtt aagcagttcg agcgcggttc ggatcacggc
    18721 ctcgcgttgg agcttgttca ttcgcgaatt ctcatgtttg acagcttatc atcgataagc
    18781 tttaatgcgg tagtttatca cagttaaatt gctaacgcag tcaggcaccg tgtatgaaat
    18841 ctaacaatgc gctcatcgtc atcctcggca ccgtcaccct ggatgctgta ggcataggct
    18901 tggttatgcc ggtactgccg ggcctcttgc gggatatcgt ccattccgac agcatcgcca
    18961 gtcactatgg cgtgctgcta gcgctatatg cgttgatgca atttctatgc gcacccgttc
    19021 tcggagcact gtccgaccgc tttggccgcc gcccagtcct gctcgcttcg ctacttggag
    19081 ccactatcga ctacgcgatc atggcgacca cacccgtcct gtggatcctc tacgccggac
    19141 gcatcgtggc cggcatcacc ggcgccacag gtgcggttgc tggcgcctat atcgccgaca
    19201 tcaccgatgg ggaagatcgg gctcgccact tcgggctcat gagcgcttgt ttcggcgtgg
    19261 gtatggtggc aggccccgtg gccgggggac tgttgggcgc catctccttg catgcaccat
    19321 tccttgcggc ggcggtgctc aacggcctca acctactact gggctgcttc ctaatgcagg
    19381 agtcgcataa gggagagcgt cgaccgatgc ccttgagagc cttcaaccca gtcagctcct
    19441 tccggtgggc gcggggcatg actatcgtcg ccgcacttat gactgtcttc tttatcatgc
    19501 aactcgtagg acaggtgccg gcagcgctct gggtcatttt cggcgaggac cgctttcgct
    19561 ggagcgcgac gatgatcggc ctgtcgcttg cggtattcgg aatcttgcac gccctcgctc
    19621 aagccttcgt cactggtccc gccaccaaac gtttcggcga gaagcaggcc attatcgccg
    19681 gcatggcggc cgacgcgctg ggctacgtct tgctggcgtt cgcgacgcga ggctggatgg
    19741 ccttccccat tatgattctt ctcgcttccg gcggcatcgg gatgcccgcg ttgcaggcca
    19801 tgctgtccag gcaggtagat gacgaccatc agggacagct tcaaggatcg ctcgcggctc
    19861 ttaccagcct aacttcgatc attggaccgc tgatcttcac ggcgatttat gccgcctcgg
    19921 cgagcacatg gaacgggttg gcatggattg taggcgccgc cctatacctt gtctgcctcc
    19981 ccgcgttgcg tcgcggtgca tggagccggg ccacctcgac ctgaatggaa gccggcggca
    20041 cctcgctaac ggattcacca ctccaagaat tggagccaat caattcttgc ggagaactgt
    20101 gaatgcgcaa accaaccctt ggcagaacat atccatcgcg tccgccatct ccagcagccg
    20161 cacgcggcgc atctcgggca gcgttgggtc ctggccacgg gtgcgcatga tcgtgctcct
    20221 gtcgttgagg acccggctag gctggcgggg ttgccttact ggttagcaga atgaatcacc
    20281 gatacgcgag cgaacgtgaa gcgactgctg ctgcaaaacg tctgcgacct gagcaacaac
    20341 atgaatggtc ttcggtttcc gtgtttcgta aagtctggaa acgcggaagt cccctacgtg
    20401 ctgctgaagt tgcccgcaac agagagtgga accaaccggt gataccacga tactatgact
    20461 gagagtcaac gccatgagcg gcctcatttc ttattctgag ttacaacagt ccgcaccgct
    20521 gccggtagct attgactatc cggctgcact agccctgcgt cagatggctc tgatccaagg
    20581 caaactgcca aaatatctgc tggcaccgga agtcagcgcc ctgcaccatt atgttccgga
    20641 tctgcatcgc aggatgctgc tggctaccct gtggaacacc tacatctgta ttaacgaagc
    20701 gctggcattg accctgagtg atttttctct ggtgccgccc tatccctttg tgcagcttgc
    20761 cacgctcaaa ggggtttgag gtccaaccgt acgaaaacgt acggtaagag gaaaattatc
    20821 gtctgaaaaa tcgattagta gacaagaaag tccgttaagt gccaattttc gattaaaaag
    20881 acaccgtttt gatggcgttt tccaatgtac attatgtttc gatatatcag acagttactt
    20941 cactaacgta cgttttcgtt ctattggcct tcagacccct acaccgactt tgccatgtca
    21001 catgcccgtt tgcttggttt tgatctttgc ccgcggttga aggaactcaa acagcgccac
    21061 ctctttgtgc cacgcggcac caaagtgccc gcagaaatcg ctgcggtgtg cgaagccaat
    21121 gtcgacgtcg ctttgatcga aaagcattgg gatagtctgg tgcacctggc agcctcggtc
    21181 atgagcggac atgccagtgc ggtggcagct cttgcgcggt tcggttctgc cgcccagggc
    21241 gatccaatct atgaggctgg cgtgcaattg gggcggttgc tgcgtacggc gtttttggct
    21301 gactactttg tcaaggacgc tttcaggaac gagttgcgcc gggtgctcaa tcggggcgag
    21361 gctgttaacg ccctcaagcg cgccatttat accggccgga tcagcccggc gcaggccaaa
    21421 cgtgtcgatg aaatgcaggc tgtggccgat gcgttgagcc tgatggccaa catcgtgatg
    21481 gcgtggaata cctcacagat gcaggcggtc ctggatcgct ggtcgaaccg ccgccaggtc
    21541 attccaccgg aactgatcgg gaagattgcg cccaccaggc tggagagcat caacttgcgg
    21601 ggtgtgtttc gcttcccggt tgaccgctat gctgaccaaa tcctgccttc gcggccaaat
    21661 gcatcgataa ctggcaccaa tggatgaaac cgaccacggt ttgacgccac gaatcgcaga
    21721 tttgaaagtg aacaggaaag tcaatgaaat caacgatcta ccaacaccac ctccgcgcca
    21781 gtgctagctt ttcgtaccgt cacttattgc actgaaaacg aggagacccc gggcaagaac
    21841 accaatgtgt acctgggctc agccgaactc tcggccatct gctccaagct gggccgtatt
    21901 cccagcaagg aagaatatct ggccgacgtg ggcgtcatta accagagcag cgacaagatc
    21961 taccagtacc tgaacttcga ccagatcgaa gaatatgtgg agaacgccaa ggaagcgact
    22021 gcctgagcgg cgatggctcc ctgaaacaac aaacggccct tcggggccgt tttgctgcgt
    22081 agcctggctg aggagaagtc tgcagaatgc tgtgtattta cacagtattt atgccagcca
    22141 cctccaagcc caagctctac aacccgcgcc accccgagcg cacgctgctc taccaaacgg
    22201 tggccgagca ttacgagacc tggcttgatc tggccagcgc cggccagttc gacggccagg
    22261 gcgaccaccg cagccccaag ccctatgtgc gccaagcgtt tgccaagtac ctggaatgcg
    22321 gcatctttgc ccacggcttt gcccgtgccc gctgcgacga ctgcggacac gactttctgg
    22381 tggccttttc ctgcaaaggc cggggcgtct gcccctcgtg caccacgcgg cgcatggccg
    22441 agacagcggc acacctcacc gaccacgtct tcccccgcct gccagtgcgc cagtgggtgc
    22501 tgtcggttcc caagcggctg cgctacttta tgcaacgcga cagcgtggtg ctgggcatgg
    22561 tgttgcgcat cttcttgcgc gtcattgagc aaaccctgca agccaacagc ccatgcgcag
    22621 cgcatgcgaa caaggccgcc ctgcacatcg gtgcagtcgc cttcattcac cgctttggct
    22681 ccagcctgaa cgagcatgtg catttccatg tgtgcgtggt cgatggcatg tttgaggcgg
    22741 tggcagggga ggcgagtgag cagggcaccc gcaccacagc gatcagcgtc atgtttcacc
    22801 cggctatcgg catcgacccc gaagcggtga cccaagccca ggccagtttg cgtcggcgca
    22861 tcctgcgcgc ctttgtgggc cggggcctgc tcgaaggctt cgaggcccag gagatgctgg
    22921 ggtacaaaca cagtgggttt tcggtagaca ccagcgtgtg catagcagca caagaccgag
    22981 cgggcctgga gcgcctgctg cgctactgcg cacggccccc gtttgcgctg gataggctgc
    23041 gcaaagcggg cagtgagctc atttaccgct gcgccaagca gcacagcgag cctggcagtg
    23101 accggcgcga ccaacgcaag gcaaagcgag gtgttcgggc cgacgaactg cacctcacgc
    23161 cgctcgaact catcgaccgc cttgccgcgc tggtgccgcc accgcgtgcg caccgccacc
    23221 ggtactacgg cgtgctggcg cccaattcac ccctgcgggc tgcggcggtt gcactgggcg
    23281 caggccaaac cgcaggcgcg ggcacgggca cggcacagcc cgagccaggc ggtgtgaccg
    23341 cagcggtgga tgccatggga gtggccacgg tcggtggtcc cagccagccc gagcccaccc
    23401 agccagctct gcccaaacgc tcagctcaca ttctgtgggc ggtgctgatc gcccgcatct
    23461 acgaggtgtt gccgctgttg tgcccgctct gcggtggcca gatgcgcatc atcgctttca
    23521 tcacctacag tgccgacctc cggcacatcc tggagcacat cggggtggag acagagccgc
    23581 ctcgcatcgc gccagcacgc gggccgccgc tgtgggatgg gtgcgatgtg ccgatgggcg
    23641 atggtgtcga ggttgagcca gattggggcg aggcggccca accggcgccg gactttgagg
    23701 tcgatcagcg cgtcagttgg taagggaagg cagcagcggt ttggccgcgc ggcagggctg
    23761 cgtctgtcac tgccaaaaaa tgtgcaaacc gaaaaatctc gggctactgg cgctgatcaa
    23821 gcgctcaggc aggctcagcc tgaaggcctg tgatgcccaa aacctgggcc ataatcgtcc
    23881 tcctgtggtt ggatttccta tccgcaagct taaagagtta ctgacgaaga aaggtgcaaa
    23941 agtattaatg acccgtgaaa tagatgattc actagatgat catataccga ataatggaag
    24001 ccgtcatcgt gaagatttaa attcaagagt aaagattgtt aataacagta aagtagatat
    24061 cttgttaagt attcatgtaa accataataa aaatgcaaat aaaataggac ctataatctt
    24121 ttacaataca agtagtgaag aaagcaagta ttttgcaaat catatacaag agtatttaaa
    24181 taatctttcg tcatataagg aaatagatat agggactaag cataaagcaa caccaggaga
    24241 ctattatctt ttgcgaaata tctcaccacc aggagtaatt attgaaatgg ggtttatctc
    24301 aaatgaaagt gataggaggc ttctattgga taataaacat ctagatgaaa ttgtagaact
    24361 aatcacaaag ggtattatcg attactttaa tgcagatcgt taataacact taaaaagaaa
    24421 ttcacagaat gttttctgct aacaacatta aaattgctag atgcttacag taaattcgat
    24481 aatcagcctg tacaagaagt gatttaatgc catgttcatc aatattctta taaaacaatt
    24541 tatgcaaata aaggatgttt ttctccgtaa tttctttatt cccaaggaaa gtaaacatat
    24601 aatcatataa gaatctattt tcttgaagta ttatttatta attgttataa tcaactcaac
    24661 gagattaaat tgatgcgagg tgaaaaacga tgttctacat cagatatcct tgttaatttg
    24721 cgattaaggc aaaggcacga agtcctccag gttaatttga ttacatgtct aaaattaaaa
    24781 aaatggagga atttaaatgc aaattataaa tatgactcaa gtaaataaaa cacaactaat
    24841 ccaagcagcc caaatattga ctgatagtat tccaattggt tggccaacac ttcatgacgc
    24901 tatggatgaa ataaaggagc gcttgattcc agaaaacaca ttacttgctg ctattgaaaa
    24961 tgatattgta atcggttggg gcggtatact tgcacccatg tataatggaa atgtattcga
    25021 actacatccg ttagctgttc gcagtgacaa gcgaaatcta ggtattggga ggacaatcgt
    25081 aacagctctt gaggatgaag caagaaagca aggtggcttg acaatacatt tgggtgctga
    25141 cgatgaagga ggcgatgggg aaacatcttt tgcaaatgtt gatttgtatg atgatttacc
    25201 aggaaaaata aacaacttca atgccggcac tcatcaatct ggattctact taaagctcgg
    25261 atataagatt atcggagtta tgcctgacgc aaacggaata ggaaaaccgg atatttattt
    25321 cggcaaagga ttataaaaag gatagaattg tatattccat tagtaagagt taaggatatc
    25381 taaacttgta aagggcaagt tagatttcta gctatgacaa ataaataagt atttaaaagt
    25441 aaacagctta aaggattgag tttcatcctt taagctgtta ttattaaaac tctgttttct
    25501 atagattttc tataaaaatt taattatcct ctttattttc gattagtaaa aatcctgact
    25561 ttttcaaagg ggatattata gaattataaa taagactaac taatattaca gatactacag
    25621 catttataaa tgtagttact gcacttaact ttgctagtat tgatgctagt tcttgtggtt
    25681 gccctagaat atatagtttg taaaagtatc ctacaatagg atcaaaaata acattaaaag
    25741 ttaatccaca tattgaagaa ataagaaccc atttaaatac ataaccctta ttattgctat
    25801 ggtttatttt agcaaaatta tgagcaacta accctgttat taagccaata catagtttta
    25861 atacaaatgt cttcggtgct acagtaatgt atacag
//
