LOCUS       NZ_AP022199            28179 bp    DNA     circular CON 02-DEC-2023
DEFINITION  Klebsiella sp. WP7-S18-CRE-03 plasmid pWP7-S18-CRE-03_4, complete
            sequence.
ACCESSION   NZ_AP022199
VERSION     NZ_AP022199.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00194569
            Sequence Read Archive: DRR199405
            Assembly: GCF_014169535.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella sp. WP7-S18-CRE-03
  ORGANISM  Klebsiella sp. WP7-S18-CRE-03
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Sekizuka,T., Itokawa,K., Yatsu,K., Inamine,Y. and Kuroda,M.
  TITLE     complete genome sequences of Klebsiella sp. WP7-S18-CRE-03 isolated
            from wastewater treatment plant effluent
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28179)
  AUTHORS   Sekizuka,T., Itokawa,K., Yatsu,K., Inamine,Y. and Kuroda,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2019) Contact:Tsuyoshi Sekizuka National Institute
            of Infectious Diseases, Pathogen Genomics Center; 1-23-1 Toyama,
            Shinjuku-ku, Tokyo 162-8640, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: flye v2.5; minimap v0.2-r124; racon v1.1.0;
            circlator v1.5.3; Pilon v1.18; SPAdes v3.11.1; A5-miseq v20140604
            Genome Coverage                   :: 352x
            Sequencing Technology             :: Sequel; NextSeq 500
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/02/2023 10:54:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,150
            CDSs (total)                      :: 5,031
            Genes (coding)                    :: 4,884
            CDSs (with protein)               :: 4,884
            Genes (RNA)                       :: 119
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 45 of 147
            Pseudo Genes (incomplete)         :: 101 of 147
            Pseudo Genes (internal stop)      :: 20 of 147
            Pseudo Genes (multiple problems)  :: 16 of 147
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP022199.1.
            Annotated by DFAST v.1.2.3 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28179
                     /organism="Klebsiella sp. WP7-S18-CRE-03"
                     /mol_type="genomic DNA"
                     /strain="WP7-S18-CRE-03"
                     /isolation_source="wastewater"
                     /db_xref="taxon:2675717"
                     /plasmid="pWP7-S18-CRE-03_4"
                     /geo_loc_name="Japan:Tokyo"
                     /lat_lon="35.5619 N 139.7531 E"
                     /collection_date="2018-08-06"
     gene            complement(join(27803..28179,1..100))
                     /locus_tag="H7R55_RS25505"
     CDS             complement(join(27803..28179,1..100))
                     /locus_tag="H7R55_RS25505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009268104.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="WP_218188518.1"
                     /translation="MNLTDGVLAALLLGGWYGGFAGAIGMTIADLLDPVYITVAPKTFV
                     LKLCIGLITGLVAHNFAKINHSNNKGYVFKWVLISSICGLTFNVIFDPIVGYFYKLYIL
                     GQPQELASILAKLSAVTTFINAVVSVILVSLIYNSIISPLKKSGFLLIENKEDN"
                     /name="ECF transporter S component"
     gene            <98..>643
                     /locus_tag="H7R55_RS25510"
                     /old_locus_tag="WP7S18C03_P40010"
                     /pseudo=""
     CDS             <98..>643
                     /locus_tag="H7R55_RS25510"
                     /old_locus_tag="WP7S18C03_P40010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011349284.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            1028..2431
                     /locus_tag="H7R55_RS25515"
                     /old_locus_tag="WP7S18C03_P40020"
     CDS             1028..2431
                     /locus_tag="H7R55_RS25515"
                     /old_locus_tag="WP7S18C03_P40020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001567368.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element ISKpn21 family transposase"
                     /protein_id="WP_182928924.1"
                     /translation="MSAESSGVFTLKEINRIKIIQDVIERRITTRRAAEHLGISDRQCR
                     RLLARYREGGPLGMASRRCGMRGNRQLPPGLADQALELIKTRYADFGPTLAREKLEELH
                     GLFLGKETVRRIMVRAGLWVPRKQRAARIPQPRYRRPCTGELIQIDGCDHDWFEGRGPA
                     CTALVYVDDATSKLMELLFVKSESTFSYFEATRRYINKHGKPLALYSDKAGVFRVNNKH
                     ATGGDGHTQFGRAMHELNIQTICAETSPAKGRVERAHLTLQDRLVKELRLQGICSMEAA
                     NDFAEAYMADYNRRFGKVPRHDFDVHRAVEHDEDLGLIFTVREKRKVSKSLTIQYDKML
                     YLIEDSELSRRAIGKYIDVYHYPDGRKELRLNGTLLPYSTYDRLSEIDQGAIVDNKRLG
                     RTLEFISLVQSKRDNTRSQSIPAGDGPSRRRPKQEGKKSQRSLDNDDMLEALKQLQSRS
                     EDIFGKRAR"
                     /name="ISNCY-like element ISKpn21 family transposase"
     gene            complement(2460..3092)
                     /locus_tag="H7R55_RS25520"
                     /old_locus_tag="WP7S18C03_P40030"
     CDS             complement(2460..3092)
                     /locus_tag="H7R55_RS25520"
                     /old_locus_tag="WP7S18C03_P40030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004883463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001567369.1"
                     /translation="MLRYELTPNNAGFILWGDSEALNELHELIHYIVDESPLIKVKDGF
                     MLSLAYDIRKAREGNRRVEQHQYDQHDTYKLYGVELLWPLVLVQSSILRNSMGYIQTDK
                     NQLSVMYAFEYLIESALTESERTTSNDIMLTVKYASDSDFNFIEDNIDSRCCYFISLSP
                     EQRKKQLISIVRSFHSLWGKYAREKQDIKMLNEMNNTSWVWPDNINW"
                     /name="hypothetical protein"
     gene            complement(3572..3898)
                     /locus_tag="H7R55_RS25525"
                     /old_locus_tag="WP7S18C03_P40040"
     CDS             complement(3572..3898)
                     /locus_tag="H7R55_RS25525"
                     /old_locus_tag="WP7S18C03_P40040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227674294.1"
                     /translation="MKTMPERFIDELNKTVQGVWDDLKPTETQGKKKGQPKALPVFSIH
                     ADGLVLSVETWKNPRRVLNPLCTLQHGEIAPFWMHEAWLEAMRRIVDLLDTLTAAPAEA
                     LESQ"
                     /name="hypothetical protein"
     gene            complement(4010..>4543)
                     /locus_tag="H7R55_RS25530"
                     /old_locus_tag="WP7S18C03_P40050"
                     /pseudo=""
     CDS             complement(4010..>4543)
                     /locus_tag="H7R55_RS25530"
                     /old_locus_tag="WP7S18C03_P40050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]; GO:0019748 - secondary metabolic process [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family protein"
                     /name="aminoglycoside phosphotransferase family protein"
     gene            complement(4576..5181)
                     /locus_tag="H7R55_RS25535"
                     /old_locus_tag="WP7S18C03_P40060"
     CDS             complement(4576..5181)
                     /locus_tag="H7R55_RS25535"
                     /old_locus_tag="WP7S18C03_P40060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            5276..8173
                     /locus_tag="H7R55_RS25540"
                     /old_locus_tag="WP7S18C03_P40070"
     CDS             5276..8173
                     /locus_tag="H7R55_RS25540"
                     /old_locus_tag="WP7S18C03_P40070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            <8244..10163
                     /locus_tag="H7R55_RS25545"
                     /old_locus_tag="WP7S18C03_P40080"
                     /pseudo=""
     CDS             <8244..10163
                     /locus_tag="H7R55_RS25545"
                     /old_locus_tag="WP7S18C03_P40080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138082.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(10077..10622)
                     /locus_tag="H7R55_RS25550"
                     /old_locus_tag="WP7S18C03_P40090"
     CDS             complement(10077..10622)
                     /locus_tag="H7R55_RS25550"
                     /old_locus_tag="WP7S18C03_P40090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227674296.1"
                     /translation="MRIKIKGEITAERLAEALHAAAEKYEAVRPGHKVYGANLYLTAFD
                     ADGLPFDLVDHRGEPLSITIEAKSGELVKPALTAEGEAHRQKAKEEARRQAEEAEAEAQ
                     RRHRQTLDEYEQERQKRRKKEAEARKQFEDANAITAELGVVCGRGRNPTLRLWPAIFSG
                     EIDVFPSERRNMGQEIGR"
                     /name="hypothetical protein"
     gene            complement(10619..11257)
                     /locus_tag="H7R55_RS25555"
                     /old_locus_tag="WP7S18C03_P40100"
     CDS             complement(10619..11257)
                     /locus_tag="H7R55_RS25555"
                     /old_locus_tag="WP7S18C03_P40100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6753 family protein"
                     /protein_id="WP_009873359.1"
                     /translation="MSDLDDSFAKLLGRQPSDAERQSLYRVRDALGLKNNDALWLVLMA
                     LQHYQGQYEKFPQAIAQAAKDTLVNFKVTADATVKASAEAAKADLAQAVAAAAQEVAHN
                     TSAKQMWQWAAGCIAVAFLCVGLFGWYMHSSGKDSGYQAGYGAGYTEAKDEKAAAAWAN
                     TPEGRLAYRFAQTGSLASLAKCDRPGWYVEKGVCYVKPASDGTYGWRLP"
                     /name="DUF6753 family protein"
     gene            complement(11250..11933)
                     /locus_tag="H7R55_RS25560"
                     /old_locus_tag="WP7S18C03_P40110"
     CDS             complement(11250..11933)
                     /locus_tag="H7R55_RS25560"
                     /old_locus_tag="WP7S18C03_P40110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein mobD"
                     /protein_id="WP_009873358.1"
                     /translation="MAKSIYLIGGSKGGVGKSLVTMATVDYLQERGESVLLIESDTSNP
                     DVWKAYKESTETELINLDEADGWIQLVNLCDSKPDSVVVINTAARNNKGVSAYGETLNS
                     TLEELKRKLVTLWVINRQRDSLELLKEYMDAIPNADVHVVRNGHFGEEKKFELYNGSKL
                     RTAVEERGGKSVTFPDMADRVSDDIYSKRMSIAVALKELPIGNRAELTRWRNEAKKVLE
                     AVVHE"
                     /name="protein mobD"
     gene            complement(11946..12302)
                     /locus_tag="H7R55_RS25565"
                     /old_locus_tag="WP7S18C03_P40120"
     CDS             complement(11946..12302)
                     /locus_tag="H7R55_RS25565"
                     /old_locus_tag="WP7S18C03_P40120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein mobC"
                     /protein_id="WP_047706562.1"
                     /translation="MKYTTEQLEAIASKLREMPPVEKKKQEHSKQEAVRVLSKEIAALQ
                     KRGYTLDQISETLRGEGLSIATPTLKSYLQRAKPAKKAPVQAPGDTPPPLPADKKPADT
                     SKATFTPKPDSDDI"
                     /name="protein mobC"
     gene            12612..12923
                     /locus_tag="H7R55_RS25570"
                     /old_locus_tag="WP7S18C03_P40130"
     CDS             12612..12923
                     /locus_tag="H7R55_RS25570"
                     /old_locus_tag="WP7S18C03_P40130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003869.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_009873356.1"
                     /translation="MPFETQGPEPLDAVINVRLTAAEKARLKEDADLAGLSMSELVRRR
                     YFGRPIIANADAVMLKELRRIGGLLKHIHNESGGVYSKETAGALVALKDYFRKLNDDR"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            12913..15585
                     /gene="traI"
                     /locus_tag="H7R55_RS25575"
                     /old_locus_tag="WP7S18C03_P40140"
     CDS             12913..15585
                     /gene="traI"
                     /locus_tag="H7R55_RS25575"
                     /old_locus_tag="WP7S18C03_P40140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI/MobA(P) family conjugative relaxase"
                     /protein_id="WP_182930712.1"
                     /translation="MIVKKVPNPKKSASKAQRIGQLTSYVRSPESESPQEKCLYAGARG
                     FMMDDPKSQTAEMIALSQEAVRSKDTINHYVLSWREGEQPSPEQVEEAVSIFMDELGWK
                     DHQAIYGLHSDTDNIHLHIVINRVHPETLKIVEKNRGFDIELAHKAIARIEHAQGWQRE
                     QNGRYQVLENGELGRAPYDPEKPRQPDQKKRDMENRTGEKSAHRIAIEDGAAIIKQAQT
                     WEQLHRELAAKGMRYEKTGSGATVFVGDVGVKASDVDRNASLAKMQKRLGEYQPAPQRQ
                     QVAPREPEPIKPDVPGWKDYISGRKAHYAEKNADKLAQDKRQEQERKQLAEQQKARRDE
                     LMRGNWKGKGEVLNAMRSVIAAEQAAEKAALKEKHQKEREQHRQRFRPYPDLEQWQRMQ
                     KSPELAEQWRHRASEPQRIEGDRSEPPTPRDIRAYQPEIVGQQVHYSRKEEAGRGGGVS
                     FVDKGKSIDIHDWRNRDSTLAALQLSAQKWGSFTVMGNDEYKAMCGKLAAEHGFKITNP
                     ELQESIQQERQRIQQERVQAMKSEQLKQFERYAEAVGAERYRVTSIKMREDGSKQTFIL
                     DKKDGITRGFTPQEIEQRTPEMQRLQRRGENLYYTPLSDKKHHILIDDMNREKLERLIR
                     DGYQPAAVLESSPGNYQAIITVPKLGTAHDKDVGNRLSDALNREYGDPKLSGAIHPHRA
                     PGYENRKPKHQREDGSYPEVRLLKAERRECIKALALSSQIDAEYQRQAALKAQQPERSK
                     AKPALELAAASGSAIDAYQRHYRDVLKRQRGGEVDLSRLDSMIAVRMRVTGHDQAAIEG
                     AIRQCAPATRQKDEGRDWNDYAQRTARYAYSAAGDRQAAELGKYRQQWEKLEGREPVRQ
                     QEQAKAQKIERDNSPGMSL"
                     /name="traI"
     gene            15652..15876
                     /locus_tag="H7R55_RS25580"
                     /old_locus_tag="WP7S18C03_P40150"
     CDS             15652..15876
                     /locus_tag="H7R55_RS25580"
                     /old_locus_tag="WP7S18C03_P40150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin MazE family protein"
                     /protein_id="WP_043149934.1"
                     /translation="MATAHVNQRVQKHRDALRMAGLRPVQIWVPDTRRPDFAEECRRQC
                     LLVAQADSADTAMQQFMDEALADVDGWTE"
                     /name="antitoxin MazE family protein"
     gene            15873..16199
                     /locus_tag="H7R55_RS25585"
                     /old_locus_tag="WP7S18C03_P40160"
     CDS             15873..16199
                     /locus_tag="H7R55_RS25585"
                     /old_locus_tag="WP7S18C03_P40160"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019303585.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003723 - RNA binding [Evidence IEA]; GO:0004521 - RNA
                     endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_009873354.1"
                     /translation="MMRGDLVTIAMQGDFGKPRPALVVQANQFSEHGSVTVLPVTSTLN
                     AAPLLRVTVQPSAENGLQKPSQVMVDKAMTVLRSKVGPAFGRIDADALLEVERCLAVFL
                     GIAK"
                     /name="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     gene            16196..16522
                     /locus_tag="H7R55_RS25590"
                     /old_locus_tag="WP7S18C03_P40170"
     CDS             16196..16522
                     /locus_tag="H7R55_RS25590"
                     /old_locus_tag="WP7S18C03_P40170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009873353.1"
                     /translation="MKTIYTIPAPDSLGAMIEVYGEPENAWYEWRIIDGGRTVRDTGTE
                     GHSAFQGRQYGQAEIALRDALMFASGLPIDGDTPTDAASLEAGYAAKAKAEAARQGAGT
                     PGSA"
                     /name="hypothetical protein"
     gene            16551..17429
                     /locus_tag="H7R55_RS25595"
                     /old_locus_tag="WP7S18C03_P40180"
     CDS             16551..17429
                     /locus_tag="H7R55_RS25595"
                     /old_locus_tag="WP7S18C03_P40180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_009873352.1"
                     /translation="MALDIMAAFTNEPPELDFIWPGFLAGTVGALVAPGATGKSFFALE
                     AAMSIACSVAGGDLVGLAPAHTGRVVYLAGEDPQPALVRRVHAIGQHLNQSAREAIAEN
                     LMLEPIMGKRLNVMDEAHLRRVIDYSAGARLIVLDTLSRIHSLDENSNGDMAHLVSVLE
                     HIAATTGAAVLYLHHVNKGSARDGQTDQQQAARGASALIDNARWCGYVAKMTEQEAERL
                     SDRGFDRAPIGNERRGLFVRFGVSKQNYDATPLDRWYQRHTGGVLLPVELQEIKRESGN
                     KGGKGYDSAAY"
                     /name="helicase RepA family protein"
     gene            17410..18402
                     /gene="repC"
                     /locus_tag="H7R55_RS25600"
                     /old_locus_tag="WP7S18C03_P40190"
     CDS             17410..18402
                     /gene="repC"
                     /locus_tag="H7R55_RS25600"
                     /old_locus_tag="WP7S18C03_P40190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_009873351.1"
                     /translation="MTQQRIKPAYAKFDPAHVFDGLFVPTKGKKRGRLYVPPRRFGDSE
                     ISFQGFEQLGADDQSILLAVSAQLGIDGLMIEAKPPGEIGQQLRLALDFDNDDGRPLKT
                     KKTSLRSLLIDAGYDDPESGAALARIKESLNRMGNAQIREINHATGWDYRCNLLSSRFN
                     HKTGEIFVAVNPRLTGAVFREQHVKVSLFERNELESEAAKLLHCWLCSNIRLGRSLGNG
                     NGAHIDTLAPHVWGKAAWEEASTKVRSVRRGQLRDALDEISDRTRGLQGGMGWAIDQTS
                     SGLVLVSRPKELPFLEGEHDMRPSEYHDLMSQPPMQEPDLFDPQDWTPD"
                     /name="repC"
     gene            complement(18455..19834)
                     /locus_tag="H7R55_RS25605"
                     /old_locus_tag="WP7S18C03_P40200"
     CDS             complement(18455..19834)
                     /locus_tag="H7R55_RS25605"
                     /old_locus_tag="WP7S18C03_P40200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873366.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_009873366.1"
                     /translation="MLTGIKLRANPTSHQKLILSQWMGCARSIWNAKVEEERYYRTYAR
                     KYCTIGTYAPIDQTTSQFKSKELSPWLSECPSQILRNSAVNWYQTYQKFMSGKCGRPKR
                     KPKTDKGSIYLTREVFRFDHCDDGNVRLFIGTKTNNIGYLSFKAHGKFEIPNSLYVRKE
                     RGHYYVSFCYEQGQPDRKLSTNEEHLAFLQGATREYLEEHTMGVDRGVAIPVCAGEQTY
                     DFTHSQKKNMSKADRYIKRLQRKLARQQKGSNRRAKTKHRIAVHHAKKANIRNDFAHKT
                     SRLLVDSSAKIIVFEALRTARMTRRPKAKQDEQGRFISNKAKQKAGLNKSILNVGWHVI
                     ETYTYYKAYSSSKAVFKIPAPTTSQECAKCGHTHPDNRKTQALFVCGNCGNTDNADHNA
                     SLVIKKRAINLILDTGTVLSGDGVLRTQSDSGRGGNRKTGRAKSSTSSAQRSVKKEKLA
                     A"
                     /name="RNA-guided endonuclease TnpB family protein"
     gene            19911..20366
                     /gene="tnpA"
                     /locus_tag="H7R55_RS25610"
                     /old_locus_tag="WP7S18C03_P40210"
     CDS             19911..20366
                     /gene="tnpA"
                     /locus_tag="H7R55_RS25610"
                     /old_locus_tag="WP7S18C03_P40210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016659780.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="WP_009873365.1"
                     /translation="MYDWRTGRSCIFKNNVHLVFVTKYRRGVFTKEMLERTEAIMKETC
                     EQMDCELLEFGGEDDHIHMMVSVHPKLAISNLVSKLKGKSSYMIRREYWDRVKTMLWGN
                     HFWSPSYCVVSCGGVALDVVREYINNQNEPPSEKAMKTSQALKQRKE"
                     /name="tnpA"
     gene            complement(20389..21024)
                     /gene="tetR(C)"
                     /locus_tag="H7R55_RS25615"
                     /old_locus_tag="WP7S18C03_P40220"
     CDS             complement(20389..21024)
                     /gene="tetR(C)"
                     /locus_tag="H7R55_RS25615"
                     /old_locus_tag="WP7S18C03_P40220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(C)"
                     /protein_id="WP_009873364.1"
                     /translation="MNKLQREAVIRTALELLNDVGMEGLTTRRLAERLGVQQPALYWHF
                     KNKRALLDALAEAMLTINHTHSTPRDDDDWRSFLKGNACSFRRALLAYRDGARIHAGTR
                     PAAPQMEKADAQLRFLCDAGFSAGDATYALMAISYFTVGAVLEQQASEADAEERGEDQL
                     TTSASTMPARLQSAMKIVYEGGPDAAFERGLALIIGGLERSACAISLL"
                     /name="tetR(C)"
     gene            21117..22307
                     /gene="tet(C)"
                     /locus_tag="H7R55_RS25620"
                     /old_locus_tag="WP7S18C03_P40230"
     ARG             21118..22304
                     /name="tet(C)"
                     /gene="tet(C)"
                     /gene_name="tetracycline efflux MFS transporter Tet(C)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22211..22549
                     /locus_tag="H7R55_RS25625"
     CDS             22211..22549
                     /locus_tag="H7R55_RS25625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005291943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002310911.1"
                     /translation="MERVGMDCRRRPIPCLPPRVASRCMEPGHLDLNGSRRHLANGFTT
                     PRIGANQFLRRTVNAQTNPWQNISIASAISSSRTRRISGSVGSWPRVRMIVLLSLRTRL
                     GWRGCLTG"
                     /name="hypothetical protein"
     gene            22757..>23053
                     /locus_tag="H7R55_RS25635"
                     /old_locus_tag="WP7S18C03_P40250"
                     /pseudo=""
     CDS             22757..>23053
                     /locus_tag="H7R55_RS25635"
                     /old_locus_tag="WP7S18C03_P40250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /name="tyrosine-type recombinase/integrase"
     gene            <23263..23970
                     /locus_tag="H7R55_RS25640"
                     /old_locus_tag="WP7S18C03_P40260"
                     /pseudo=""
     CDS             <23263..23970
                     /locus_tag="H7R55_RS25640"
                     /old_locus_tag="WP7S18C03_P40260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558120.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            <24115..24309
                     /locus_tag="H7R55_RS25645"
                     /old_locus_tag="WP7S18C03_P40270"
                     /pseudo=""
     CDS             <24115..24309
                     /locus_tag="H7R55_RS25645"
                     /old_locus_tag="WP7S18C03_P40270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018229750.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            24414..26006
                     /locus_tag="H7R55_RS25650"
                     /old_locus_tag="WP7S18C03_P40280"
     CDS             24414..26006
                     /locus_tag="H7R55_RS25650"
                     /old_locus_tag="WP7S18C03_P40280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008328818.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="WP_020229221.1"
                     /translation="MPATSKPKLYNPRHPERTLLYQTVAEHYETWLDLASAGQFDGQGD
                     HRSPKPYVRQAFAKYLECGIFAHGFARARCDDCGHDFLVAFSCKGRGVCPSCTTRRMAE
                     TAAHLTDHVFPRLPVRQWVLSVPKRLRYFMQRDSVVLGMVLRIFLRVIEQTLQANSPCA
                     AHANKAALHIGAVAFIHRFGSSLNEHVHFHVCVVDGMFEAVAGEASEQGTRTTAISVMF
                     HPAIGIDPEAVTQAQASLRRRILRAFVGRGLLEGFEAQEMLGYKHSGFSVDTSVCIAAQ
                     DRAGLERLLRYCARPPFALDRLRKAGSELIYRCAKQHSEPGSDRRDQRKAKRGVRADEL
                     HLTPLELIDRLAALVPPPRAHRHRYYGVLAPNSPLRAAAVALGAGQTAGAGTGTAQPEP
                     GGVTAAVDAMGVATVGGPSQPEPTQPALPKRSAHILWAVLIARIYEVLPLLCPLCGGQM
                     RIIAFITYSADLRHILEHIGVETEPPRIAPARGPPLWDGCDVPMGDGVEVEPDWGEAAQ
                     PAPDFEVDQRVSW"
                     /name="IS91 family transposase"
     gene            26063..26686
                     /locus_tag="H7R55_RS25655"
     CDS             26063..26686
                     /locus_tag="H7R55_RS25655"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: protein motif:HMM:NF013670.3"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]; GO:0008745 - N-acetylmuramoyl-L-alanine amidase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_182930711.1"
                     /translation="MCKPKNLGLLALIKRSGRLSLKACDAQNLGHNRPPVVGFPIRKLK
                     ELLTKKGAKVLMTREIDDSLDDHIPNNGSRHREDLNSRVKIVNNSKVDILLSIHVNHNK
                     NANKIGPIIFYNTSSEESKYFANHIQEYLNNLSSYKEIDIGTKHKATPGDYYLLRNISP
                     PGVIIEMGFISNESDRRLLLDNKHLDEIVELITKGIIDYFNADR"
                     /name="N-acetylmuramoyl-L-alanine amidase"
     gene            27080..27619
                     /locus_tag="H7R55_RS25660"
                     /old_locus_tag="WP7S18C03_P40290"
     CDS             27080..27619
                     /locus_tag="H7R55_RS25660"
                     /old_locus_tag="WP7S18C03_P40290"
                     /inference="COORDINATES: protein motif:HMM:NF012792.3"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_070085966.1"
                     /translation="MQIINMTQVNKTQLIQAAQILTDSIPIGWPTLHDAMDEIKERLIP
                     ENTLLAAIENDIVIGWGGILAPMYNGNVFELHPLAVRSDKRNLGIGRTIVTALEDEARK
                     QGGLTIHLGADDEGGDGETSFANVDLYDDLPGKINNFNAGTHQSGFYLKLGYKIIGVMP
                     DANGIGKPDIYFGKGL"
                     /name="GNAT family N-acetyltransferase"
     ARG             complement(4011..4525)
                     /name="APH(6)-Id"
                     /gene="APH(6)-Id"
                     /gene_name="APH(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.42"
                     /coverage="61.51"
     Typing          16552..17429
                     /name="IncQ2"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12914..15582
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.888"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gatctagtaa atctgctatt gtcattccaa tagctcccgc aaatccccca taccatccac
       61 ctagaagtaa agcagctaat acgccatcgg tgaggttcaa ttgccggaag tgattctggc
      121 cgttgacgcc caggtgcgct ttagctggat catgctcgga cgtgagccgc gctctaccga
      181 cgagctgctg atggtctatg ccggcatcat ggcccacggc accagtctga ctgcggtcga
      241 atgcgcgcgc atgattccgc aattgtctgc caccagcatt cgccaggcca tgcgctgggc
      301 gcgggacgaa cggcgtctga gccaggcctg ccaggctgtg ctggaattca tgcagcgaca
      361 cccgattgcc gccacctggg ggcggtccga tttggcatct tctgacatga tgagcatgga
      421 gaccaccaaa cgggtgtggc aagcccggct tgatcctcgg cgcaacacac cttccattgg
      481 aatctactcc catgtaaaag accggtgggg catcttccat gcgcagccct ttgtgctcaa
      541 tgagcgccag gcgggcgtgg ccattgaagg tgtcatccgc caagaaaagc tggagaccag
      601 ccagcttgct gtggataccc atggctacac ggggtttgag gtccaaccgt acgaaaacgt
      661 acggtaagag gaaaattatc gtctgaaaaa tcgattaggc tagaaagtcc gttaagtgcc
      721 aattttcgat taaaaagaca ccgttttgat ggcgttttcc aatgtacatt atgtttcgat
      781 atatcagaca gttacttcac taacgtacgt tttcgttcta ttggccttca gaccccatat
      841 ctaatcgata ggtgaaccat cctgcacaat tctgatgatt ttcatgaatc ctgtcgtttt
      901 taacataatg ggtattaagt gtagtgtgtt tgtaatggct caatagtaat gtccgcctgt
      961 ggctcaattc agatgtccgc gctatggtaa gcttcactgg tccgtttaaa ctaccgggag
     1021 gcatatcatg agcgcagaaa gctcaggagt gtttactttg aaagagatca accggatcaa
     1081 gattatacag gacgtcattg aacgtcgcat cacaacgcgc cgtgcggccg agcacctcgg
     1141 tatcagcgac aggcaatgcc gcagacttct tgcccgttac cgtgaaggcg gaccgcttgg
     1201 tatggccagc agacgatgtg gcatgcgtgg taaccgccag ttgccacccg ggctcgcaga
     1261 tcaggctctg gaactgatca agacgcgtta tgctgatttc ggtccgactc tggcgcgtga
     1321 aaagctcgaa gaactccacg gactgtttct tggcaaagaa actgtccggc gcatcatggt
     1381 gcgggctggc ttatgggttc cccgtaaaca acgtgccgca aggatccctc aaccacggta
     1441 ccggcgtccg tgtactggtg agctgataca aatagatggc tgtgatcacg actggtttga
     1501 aggccgtggc ccggcctgca ccgcgctggt ctatgttgat gatgcaacca gcaaactgat
     1561 ggaactgttg tttgttaaat cggagtccac gttttcttac ttcgaagcca cgcggcgcta
     1621 tatcaataag catggtaaac cgctggcact gtacagcgat aaagccggtg tttttcgtgt
     1681 taacaataaa cacgccacag gcggagacgg gcatactcag tttgggcgag ccatgcatga
     1741 actgaacatc cagactatct gtgcagaaac cagtcccgcc aaagggcgtg tagaacgagc
     1801 tcacctcact ttacaggatc gtctggtcaa agagctgcgg ttacagggca tttgttcaat
     1861 ggaggctgca aatgacttcg ctgaggccta tatggctgac tataaccgcc gttttggcaa
     1921 agtaccgcga catgattttg acgtacaccg tgctgtagaa catgatgagg acctggggct
     1981 tattttcact gttcgtgaaa aacgtaaagt ctcaaaatcg ttgacgatac aatatgataa
     2041 aatgttgtac ctgattgaag acagcgaact gagtcgccgt gcaataggta aatatatcga
     2101 tgtgtatcac tatcctgatg gcagaaaaga gctgcgcctg aacggtacgc tacttcccta
     2161 ctctacctac gaccgactgt cagaaatcga ccagggcgcg attgtcgata acaagcgtct
     2221 tggccgaacc ctggagttta tcagtctggt gcagagcaag cgggataaca cgcgctctca
     2281 gtcaattccc gctggagatg gcccttcccg acgacggcca aagcaggaag ggaagaaatc
     2341 ccagcgctca ctggataatg atgacatgct cgaagcactc aaacagcttc agtcacgttc
     2401 agaggacatt tttggtaaaa gagcccgctg atggtactca ctggccggac agtggttgct
     2461 caccagttga tattgtccgg ccagacccat gatgtattat tcatttcgtt cagcatcttt
     2521 atgtcctgct tttcacgggc atacttaccc cataatgaat gaaaagaacg aacaatactg
     2581 attaactgct tttttctttg ctccggagat aggctgataa aatagcagca cctgctgtca
     2641 atattatcct caatgaaatt aaaatcagag tctgatgcat attttactgt tagcataata
     2701 tcattcgacg ttgttctctc agactctgtt aatgctgatt ctatcaggta ttcaaaggca
     2761 tacatgacag acagctggtt tttgtctgtc tgaatataac ccattgagtt tctgagtatt
     2821 gaggactgta ccaggaccag aggccataaa agctcaacac cataaagctt atatgtatca
     2881 tgttgatcat actgatgttg ctcaacacga cgattacctt cccgtgcttt acgaatatca
     2941 taggcaaggg ataacataaa tccgtcttta actttaatca gtgggctttc atccacgatg
     3001 taatgaatga gttcatgtaa ttcattcagg gcttctgaat ctccccacag tataaaacct
     3061 gcattgttcg gcgttaactc gtatcgaagc atgggctcaa tcatcctgtt gtttcagtcg
     3121 gaggaaagtc tatcagtaaa gagaatgaga gatcaaagtg gtcattttaa ttgagctgga
     3181 taacggacat ttcaattgag ccttgacagt gtttgtctat caataagaga tttatctaat
     3241 ttaattcaag cccccggcgc aggtggtaac cacccccggc gcaggtggta accacccccg
     3301 gcgcaggtgg taaccacccc cggcgcaggt ggtaacctga caagccacaa aaacgcccgc
     3361 aaacccttgt cagtactgag ttttcgcgtt tttccaaaat tccggtctaa gaagttctaa
     3421 agaacttcta ccatgcgcgg ctttcagccg ccgctttagg cgtcgtctga agccttgcct
     3481 tcgggcttcg ccctgcgcgg gctaaagccc ttgcagacac acccccgccc ccgccccgcc
     3541 gctaccccct tccttgcagg cgaaaacgcc tctactggct ttctagggcc tctgccgggg
     3601 ctgcggtgag cgtatccagc agatcgacta tccgcctcat ggcttctaac cacgcttcgt
     3661 gcatccagaa tggggctatt tcgccgtgct ggagtgtgca aagcggattg agaacccggc
     3721 gcgggttctt ccatgtctcg acggaaagca ccagcccgtc cgcatggatg gaaaagactg
     3781 gtagcgcttt cggctggccc ttcttcttgc cttgcgtttc ggttggcttg aggtcgtccc
     3841 aaacgccttg cacggttttg ttcagttcgt cgatgaagcg ttccggcatg gttttcaaga
     3901 gttggggtcg tttgcgggag agggcgaaat cctacgctaa ggctttggcc aacgatattc
     3961 tccggtaaga ttgatgtgtt ccgaggggat aggagaagtc gcttgatatc tagtatgacg
     4021 tctgtcgcac ctgcttgatc gcggccgcga tagctagatc gcgttgctcc tcttctccat
     4081 ccgcgttcca agctgcggaa aggcacccat aagcgtacgc ctggtcgagc aggcgacgcg
     4141 gatcgacgtc cagcgcacga gagaatgcgt ccgccatctg tgcaatgcgt ctgggatcga
     4201 gacaaaggtc gtctctgtca gccggatcgt agaacatatt ggcggcgcca aagcccactt
     4261 caccgaccag accgacggga tctatcacca gccagccgcg actggagaac atgatgtttt
     4321 catgatgcag atcgccatgt agcccacgca gttccgaggc attgctcatc atttgatcgg
     4381 ctataatcgc cgcgtggacg tagtcagttt gacaacctgc gttttgatca tcgcgcgccc
     4441 gctgaaacaa agctgcaaag cgatcccgga tcgggagaag ggcagaaggc aggggttcct
     4501 cagatgcggc atacagcttc gccattagtt ccgctgcaat ttggggtcgg ttccggctga
     4561 gggcgaaatg acaccctaag cgttagctct gtgtcgttgc acgatgtcag cgacggtatt
     4621 cttgctgata ccgagctcgc gtgcgatcca gcgatagctg cgtccctcgg ccctcatcgc
     4681 aaccacctta ggcaaaagtc ggtctgattt tggtcgcact ccggcctgac gaccaagcct
     4741 cttaccacgt gccttcgcaa cagcaaggcc tgacttgacc cgctcgctga tgagatcccg
     4801 ctcaaactcc gcaatgccgg aaagaaacgt cgccagcatt cgtccatacg gcgacgaaag
     4861 atcgaacgcc attccattca tggctatcac ggaaaccttc cagttctcca gttcacgtag
     4921 cgtattgagc agatcgagcg tcgagcgccc ccaccgggaa agctcagtga ccaggattgc
     4981 atcaatttgt ctggactggg caagcgccag gactttcttt cgctcggccc ggtcgagttt
     5041 agttcctgaa cctgtttcct taaatattcc caccacgtcg tagccggcac ggccggcgaa
     5101 ggctcgcaga tcaaattcct ggcgttcaca agactgatcc gctgttgaaa cccggcagta
     5161 aatggcggca cgatgtccca attgaaccct cctggatttt tgtatcggaa cgccctgatt
     5221 tatatgggct ggctgttgtc caaaacagac tatacttcaa aagggacgaa tttgtatgtc
     5281 acgacgccat attttcaccg aacggcagcg agcagcgctg ttcgatctgc ccacggacga
     5341 actgtcgcta ctgaagttct acacgctggg cgatgatgac ctggaaaaca ttaggcagcg
     5401 ccgcagaccg gaaaacagga ttggctttgc cctgcaactt tgtgccttac gatatccggg
     5461 ccgtgcactg gctcctggtg agatgatccc gcgtgaagtc ctttccttcg tcggtgctca
     5521 gcttggagtt ccggctgatg cgcttctcac ttatgccaca cggcgccaaa cccgtcagca
     5581 gcacatggac acgctgcgcg aaatttacgg ctacaagacc ttcacgggcc gtggtgcccg
     5641 tgatctgcgg gagtggactt tcggccaggc cgaagatgcc agatcaaacg aggatcttgc
     5701 tcatcgtttt attgtgcggt gtcgggaaac ttccaccatt ctgcccgcag tatcgacaat
     5761 cgagcgcttg tgcgcggatg ctctggtcgc cgctgagcgg cggattgaaa cgcggattgc
     5821 ggaaaattta acagcggatg ttcgcgatca cctggacaaa cttctgagtg aaatgctcgc
     5881 cggcaatatc agtcgtttca tctggcttcg caacttcgag gttggtaaca actcggctgc
     5941 tgctaaccgt ttgctcgaca ggctcgaatt tctgcgtacc ctgaatatca atcatagtgc
     6001 tttggccagc atacctgccc atcgcattgc ccggctgcgt cggcagggtg aacgctactt
     6061 caccgacggt ttgcgtgaca tcacttcgga ccgccgctgg gcgatccttg ccgtctgtgt
     6121 tgtggagtgg gaagcggcga ttgctgatgc catagtcgaa acccatgaca ggatcgtagg
     6181 aaaaacctgg cgggaagcga agcgccagca tgacgaaaca atttccggct ctaaagccac
     6241 actcacggat acgatccgta ccttcaccgc gctgggagct tcgttgcttg aggcccgcag
     6301 tgacggaacc ccgctggaga tggctgtcgc cagttcggtt gcatgggacc ggctcgctca
     6361 actggtagcg acagggactc aactcagcaa cacgctagcc gatgagcctc ttgcatatgt
     6421 cgggcaggga taccatcgct ttcgtcgtta tgcgccccgc atgttgcgct gtctgaagct
     6481 cgaagccgcg ccggtcgccg gaccattggt agcagcagct ttgtcgatcg gagagatgaa
     6541 aggtgttgca tcgccagaaa ggcgtttcct gcggcccagc tccaaatgga accgtcattt
     6601 acgagctcag gaaaaaggag atacccgtct ttgggaagtg gcggtactct ttcacctccg
     6661 ggatgctttt cgttccggag atgtctggct cgctcattcg cgccgctatg gtgacctcaa
     6721 gcaggtactg gtgccgatga tcgcggcgca ggaaaatgca aaactggccg tgccttccaa
     6781 cccacaggat tggctggcag acagaaaggc gcgactcacg atcgctctta agcggctggc
     6841 ccgggctgcc cgtaacggca ctattccgca cggtagcata gaagatggaa cgttgcggat
     6901 cgacaggttg acagcagacg tgccggatgg tgccgaggca ctcatactgg atctgtatcg
     6961 ccgaatgccg tccgttcgga ttaccgacat gctgcttgaa gttgatgcag cccttggttt
     7021 cacagatgcg tttacccatc tgagaaccgg ggctccatgt cgcgaccgga tcggtctgct
     7081 caacgtcctg ctcgctgaag ggctcaatct gggcctgcgt aagatggcgg aagctacaaa
     7141 cacgcatgat tactggcagc tctcacgcct tgcccgctgg catgttgaaa gcgaagccat
     7201 gaaccaggca ttggcaattg tggtggccgc gcagggtaaa ctgccgatgt cacgcgtctg
     7261 ggggatgggc acgtcagcat cgagcgatgg tcagtttttc ccgacagcgc ggcatggcga
     7321 agccatgaac atggtcaatg ccaaatatgg ttctgttccc ggcctcaaag cgtatactca
     7381 cgtaagcgac cagttcgcgc cattcgcttg tcagtcgatc ccggcgaccg tgagcgaggc
     7441 accgtatatt ctcgatggac tactgatgaa cgaggtcggt cgccatgttc gcgaacagta
     7501 tgccgataca gcaggattca ccgaccattt gttcggagcc agtagcctgc tcggctacaa
     7561 tctcgttctg cgaatcaggg atctgccatc gaagcggttg tacgtattta atcccgatac
     7621 gacccccagg gagttacgca agttggtagg tggaaaagcc cgggaggatc ttatcgttgc
     7681 gaactggcct gatattttcc gttgtgccgc gacgatgacc gctggcaaaa tcaggcccag
     7741 ccaactcctg cgcaagctcg cttcttaccc acgacaaaac aaccttgcag ttgcgcttcg
     7801 tgaagttggt cgtattgaac ggaccctttt cattattgag tggatcctgg atacggacat
     7861 gcagcggcgt gctcagatcg gtcttaacaa gggagaggcc caccatgcgc tcaaaaatgc
     7921 gctccgtatc gggaggcagg gggaaattcg cgatcgcacg acagaggggc agcactaccg
     7981 aatcgctggg ctcaatttat tgactgcggt gatcatttac tggaataccg tccatcttgg
     8041 tcatgccgtc acggagcggc ggaacgaagg gttggatgtt ccccctgaat ttcttcccca
     8101 catatcccca ttgggctggg cgcacattct actgactggc gaatatcttt ggcccaagga
     8161 accgaaagct tagggtgtca tttcgccctc agccggaacc gacccctatt tgccatgcaa
     8221 aggtcgcaga cgaagcgggg gtggtgcgtg acaccctgaa atccttcgcc gagatcgggg
     8281 gcgccctggt cgatgcacag gatgatggcc agccgctggg cgatgtcatc gcgagtgggt
     8341 cagggtggga cggcttaaaa acccttgttg caatggcaac caggctgacc gccaccatgg
     8401 ccgacgatcc gctcaatcat gtgctcgacg gttatcaccg cttccgccga tacgctccac
     8461 gcatgttgcg cctgctcgat ctgcgagctg cgcccgttgc actgccgctt ctggaagctg
     8521 tgacggccct tcgtaccggt ttgaacgatg ccgcgatgac cagcttcttg cggcccagct
     8581 cgaaatggca tcgccacctt cgggcccaga gggctggcga cgctcgccta tgggagatcg
     8641 cggtgctgtt ccatctgcgc gatgcgttcc gctccggaga tgtctggctt actaggtccc
     8701 ggcgctatgg cgatctgaaa cacgcactcg ttccggcaca agccatcgcg gaaggcggtc
     8761 gtctcgctgt gccattgcgg ccggaggaat ggctggcaga ccggcaagct cgcctcgaca
     8821 tgcggttgcg cgagcttggc cgtgccgctc gcgcaggcac gatcccgggc gggtcgattg
     8881 agaacggcgt tctgcatatc gagaaactcg aagccgccgc gccgacaggc gccgaagatc
     8941 tggtgctcga tctctacaag cagatcccgc ccacgcgcat caccgatctc ctgctggagg
     9001 tggatgcggc gaccggcttc accgaagcgt tcacccatct gcgcacagga gcaccctgcg
     9061 ctgaccggat cgggctaatg aacgttatct tggcggaagg gatcaacctc ggcttgcgca
     9121 aaatggcgga tgcgacaaac acccacacct tctgggaatt gatccgcatt ggacggtggc
     9181 atgtcgaggg cgaagcctat gaccgggcgc tggccatggt ggtcgaggca caggcagcgt
     9241 tacccatggc ccggttctgg ggcatgggca cgtcggcttc gagcgacgga cagttcttcg
     9301 tcgctacaga gcaaggtgag gccatgaacc tggtcaacgc gaaatatggc aataccccgg
     9361 gcctgaaagc ttatagccac gtctccgacc aatatgcgcc gttcgcaacc caggtaattc
     9421 ctgcaacggc aagcgaagcg ccttacatcc tcgatggcct gctgatgaac gatgctggac
     9481 gccatatccg cgagcagttc accgacacgg gcggcttcac cgatcacgtc tttgccgcat
     9541 gtgccattct cggctaccgg ttcgctccgc gcatccgcga cctgccatcc aaacggctct
     9601 acgcgttcaa tccgtcggcc gccccggcgc acctgcgagc gttgatcggc ggaaaggtca
     9661 accaagccat gatcgagcgc aattggcccg acatcctgcg catcgccacc accattgctg
     9721 ccgggaccgt cgcgccaagc cagattctgc ggaaactcgc ctcctatccg cggcagaacg
     9781 agctcgcgac agccctgcgg gaagtcggtc gcgtcgagcg caccctgttc atgatcgact
     9841 ggattctgga tgccgaactc caacggcgtg cccagatcgg gctcaacaaa ggcgaagctc
     9901 atcatgcgct gaagcgggca atcagcttcc accgccgcgg tgaaatccgc gaccgttccg
     9961 ccgaaggcca gcattaccgc atcgccggca tgaatctgct cgccgccatc atcatcttct
    10021 ggaacaccat gaagctcggc gaggtcgttg caaaccagaa acgcgatgga aagctgctat
    10081 cgcccgatct cttggcccat gtttcgccgc tcggatggga acacatcaat ctcaccggag
    10141 aatatcgctg gccaaagcct tagcgtagga ttccgccccc tcccgcaaac gaccccgagt
    10201 tcggcagtga ttgcgttcgc gtcctcaaat tgctttcttg cttcggcttc ctttttccgt
    10261 cgtttttgcc gctcctgttc gtattcgtct aaggtttgcc tgtgtctgcg ctgtgcttca
    10321 gcttccgctt cttcagcttg ccttcgtgct tcctctttgg ctttctgtcg gtgtgcttca
    10381 ccctctgctg tgagtgctgg ttttaccagt tcgccagact tggcctcgat ggtgatcgaa
    10441 agcggttcgc cgcgatggtc taccagatcg aacggcagac catcagcatc gaaggcggtt
    10501 aggtagagat tggccccata gaccttgtgc cccggcctca cagcttcgta tttttctgct
    10561 gctgcgtgca gtgcttccgc taggcgttct gccgtgattt ctcctttgat cttgattctc
    10621 atggcaacct ccatccgtag gtgccatccg atgcgggctt gacgtagcac acgccttttt
    10681 cgacgtacca ccccggccta tcgcacttcg ccaagctggc gaggcttccc gtttgcgcga
    10741 agcggtaggc caagcgcccc tctggcgtgt tggcccatgc cgccgccgct ttctcgtcct
    10801 tggcttcggt gtatcccgcg ccgtatccgg cctgatagcc cgaatccttg ccgctgctgt
    10861 gcatgtacca gccgaacagg ccgacgcaca ggaaggccac cgcgatgcag cccgccgccc
    10921 actgccacat ctgctttgcc gatgtgttgt gcgcgacctc ttgcgctgct gctgctaccg
    10981 cttgcgccaa atccgccttg gctgcttccg ctgatgcttt cacggttgca tccgccgtta
    11041 ccttgaaatt gaccaaggta tctttggccg cttgtgctat cgcttgcggg aacttctcat
    11101 actggccttg gtagtgttgc aaggccatga gcaccagcca cagcgcatca ttgtttttca
    11161 ggccgagcgc atcccgaacc cggtaaagac tttgccgctc cgcgtcacta ggttgcctgc
    11221 cgagcagctt tgcaaagctg tcgtctaggt cactcatgga ctacggcctc caataccttt
    11281 ttggcctcgt tgcgccaccg cgtaagctcc gcacggttgc caatgggcag ttccttgagt
    11341 gctaccgcaa tgctcatgcg cttgctgtaa atgtcatcgc tcacacggtc ggccatgtcc
    11401 gggaatgtca ccgatttccc gccgcgttcc tctaccgccg tgcgcagctt ggagccgttg
    11461 taaagctcga acttcttttc ttccccgaag tgtccattgc gtaccacatg aacatccgca
    11521 ttcggaattg cgtccatgta ttcctttagc agttcgaggc tatcccgttg gcggttaatc
    11581 acccacagcg tgaccagctt gcgcttgagt tcttcaagcg tgctattcag tgtttcaccg
    11641 taggcgctca cgcccttgtt attccgtgct gccgtgttga ttaccacgac gctatccggc
    11701 ttgctatcgc acaggttcac tagctgaatc catccgtccg cctcatccag attgataagc
    11761 tccgtttccg tgctttcttt ataggctttc catacgtccg ggttagaggt gtcagactca
    11821 atcagcaaga cgctttcgcc gcgctcttgc aggtaatcaa ccgttgccat cgtaacaagc
    11881 gacttgccaa cgccgccctt gctgccaccg atcaggtaaa tgcttttcgc catgttgctt
    11941 actccttaaa tgtcgtcgct gtcaggtttc ggggtgaatg tcgccttcga tgtatccgca
    12001 ggcttcttat cggcggggag gggcgggggt gtgtctcccg gtgcttgcac cggggctttt
    12061 ttcgctggct ttgctctctg caagtagctc ttgagcgttg gggttgcgat gctcagacct
    12121 tcgccgcgca gcgtctcgga aatctggtca agcgtgtatc cacgcttttg caaagcggca
    12181 atctctttgg atagcacgcg cacggcctct tgcttgctgt gctcctgctt cttcttttcg
    12241 actggcggca tctcacgaag ctttgaagcg atagcctcta gctgctctgt tgtgtatttc
    12301 attctgctaa ctcctttgct cactggttgc ggagttgaca gcatagcgcc ttttatgctt
    12361 gttgcaaagt gcgtcccgtg cacctaaact gctgatatga tagtagagtg gttgagcaat
    12421 acaggatgcg gattgtcata cacatgctac gcatgttcct gccaatcccc gcctgcccat
    12481 tcggcgcttc gcttctcacg gtctggctca tcctgcaagg ggcaagcccc ttgaccccgg
    12541 acagtgcggc gctttcgctt cttactgtcc aagacacacc ccgcccccgc ccccggcgag
    12601 aaggagacat gatgccattt gaaacgcagg ggccggaacc gctggacgcc gttatcaatg
    12661 tgcggctgac cgcagcggag aaggccagat tgaaagagga cgccgacctt gccgggttga
    12721 gcatgtccga gcttgtccgc cgccgctact tcggcaggcc gatcattgcc aacgccgacg
    12781 ccgtgatgct caaggagctg cggcgcatcg gtggattgct gaagcacatc cacaacgaga
    12841 gcggaggcgt ttacagcaag gaaacagccg gggcgcttgt tgcgctcaag gactacttca
    12901 ggaagctaaa cgatgatcgt taagaaggtt ccgaatccga agaagtccgc gagcaaggcg
    12961 cagcgcatcg gccagcttac cagctatgtc cgttcgccgg agtcggagag tccgcaggaa
    13021 aagtgtctgt atgccggggc gcggggtttc atgatggacg accccaagag ccagacggca
    13081 gagatgattg cactctcaca agaagccgtg cgcagcaagg acaccatcaa tcactacgtc
    13141 ttgagttggc gcgaaggcga acagccaagc ccggagcaag tagaggaagc ggttagcatc
    13201 ttcatggatg agcttgggtg gaaagaccac caagccatct atggccttca ttccgacacg
    13261 gacaatatcc acctgcacat cgtcatcaat cgggtgcatc ccgaaacgct caagattgtt
    13321 gagaagaacc gtggatttga tattgaactg gcacacaaag ccattgcacg gattgagcac
    13381 gcccaaggct ggcagcgtga gcaaaacggg cgctatcagg tgttggagaa cggggagcta
    13441 ggccgagcgc catacgaccc ggaaaagcca cgccagcccg accagaagaa gcgggacatg
    13501 gagaaccgca ccggggagaa gtcagcccac cgcatcgcca tcgaggacgg cgcagccatc
    13561 atcaagcagg cgcagacgtg ggagcagttg caccgcgagt tagcagccaa ggggatgcgc
    13621 tacgaaaaga ccggcagcgg ggcgaccgtg tttgtcgggg atgttggcgt gaaggccagc
    13681 gatgtagacc gcaacgccag ccttgccaag atgcagaagc ggctaggtga ataccagcca
    13741 gcgccgcagc gtcagcaggt agcgccgcgc gagccggagc cgatcaagcc agacgtgccg
    13801 ggatggaagg actacatcag cgggcgcaag gcacactacg ccgagaagaa cgcggacaag
    13861 ctggcacagg acaagcggca ggagcaggag cgcaagcaac ttgccgagca gcagaaggcc
    13921 cgccgcgatg aactcatgcg cggaaactgg aaaggcaagg gcgaagtgct caacgccatg
    13981 cgcagcgtga ttgccgccga gcaggccgca gagaaagcgg ccttgaagga gaagcaccag
    14041 aaggagcgcg agcagcaccg gcagcggttc cgaccctatc ccgacctgga gcagtggcag
    14101 cggatgcaga aaagcccgga gcttgccgag cagtggcgac accgggccag cgagccgcag
    14161 cgcatcgagg gcgaccgcag cgagccgccg acgccgcgag acattcgcgc ctatcagcct
    14221 gaaatcgtgg gccagcaggt gcattacagc cggaaggaag aagcggggcg gggcgggggt
    14281 gtgtctttcg tggacaaggg caaaagcatc gatattcacg actggcgcaa ccgggacagc
    14341 acgcttgccg cgttacagct atcggcgcag aagtggggca gcttcaccgt gatggggaac
    14401 gacgaataca aggccatgtg cgggaagtta gcagcagagc acggcttcaa gatcacaaat
    14461 ccagagcttc aggagagcat ccagcaggag cggcagcgga tacagcagga aagggtgcag
    14521 gcgatgaaat cggagcagct aaagcagttc gagcggtacg cggaagcggt aggcgcagag
    14581 cgttaccggg taacgtctat caagatgcgc gaggacggca gcaagcaaac cttcatcctc
    14641 gacaagaagg acggcatcac gcggggcttc acaccgcagg agatcgagca gcgcacgccg
    14701 gagatgcagc gcctacagcg ccggggcgaa aacctctact acacgccgct atcggacaag
    14761 aagcatcaca tcctcatcga cgacatgaac cgggagaagc tggagcggct tatccgcgac
    14821 ggctaccagc ccgccgccgt gcttgaatcc agccccggca actatcaggc catcatcacc
    14881 gtgccgaagc tggggacggc ccacgataag gacgtgggca accggctgag cgatgccctg
    14941 aaccgtgaat acggcgaccc gaagctatcg ggagccatcc acccgcaccg tgcacccggc
    15001 tacgagaacc gcaagcccaa gcaccagcgg gaggacggca gctatcccga ggtgcgcttg
    15061 ctcaaggccg agcgccggga gtgcatcaag gcgctggcct tgtccagcca gatcgacgcc
    15121 gagtatcagc ggcaagcggc cttgaaggcg cagcagcccg agcgcagcaa agccaagccc
    15181 gccttggagc ttgcagcggc cagcggcagc gcgatcgacg cctaccagcg gcattatcgc
    15241 gacgtgctca agcggcagcg tggcggcgag gtggacttgt cccgcttgga ttccatgatt
    15301 gccgtgcgta tgcgcgtcac cggccacgat caagccgcca tcgagggcgc tatccgccag
    15361 tgcgccccgg ccacccggca gaaggacgag ggccgcgact ggaacgacta cgcgcagcgc
    15421 accgcccgct atgcctacag cgccgcaggc gaccgccaag ccgccgagct tgggaagtac
    15481 cgccagcagt gggagaagct ggaagggcgc gagcctgtac gccagcagga gcaggccaag
    15541 gcgcagaaga tcgagcgcga taactcgccg gggatgagtc tttaaatacc tgttgcatgt
    15601 aacttgcgag gtgcgtacaa tgttgcatgt aacttaattg gaggcttgga aatggcaaca
    15661 gcacacgtta atcagcgggt tcagaagcat cgcgatgcat tacgcatggc ggggcttcgt
    15721 ccggttcaaa tctgggtgcc ggatacgcgc cgccccgact tcgcggagga gtgccgccgc
    15781 caatgcctgc ttgtggctca ggccgacagc gccgacaccg ccatgcagca gttcatggat
    15841 gaagccttgg cagacgtgga cggctggacg gaatgatgcg cggcgacctt gtgaccatcg
    15901 ccatgcaggg cgactttggc aagccacggc ctgcgcttgt ggttcaggcc aaccagttca
    15961 gcgagcacgg cagcgttacc gtgctgcctg tcaccagcac acttaatgcc gcgccgttgc
    16021 tgcgcgtcac ggttcagccg agcgcagaga acggtttgca gaagccatcg caggtgatgg
    16081 tcgacaaggc gatgacggtg ctgcgcagca aggtagggcc agctttcggg cgcatcgacg
    16141 cggacgcact gcttgaggtt gagcgttgct tggccgtgtt cttggggatt gcgaaatgaa
    16201 aacgatctac accattcccg ccccggattc cttgggcgcg atgatcgagg tctacggcga
    16261 gccggaaaac gcttggtacg agtggcgcat catcgacggc gggcgcaccg tgcgggacac
    16321 cggcacggaa ggccacagcg cctttcaggg acgccagtac gggcaagcag agattgccct
    16381 acgtgatgcg ctcatgttcg cttctggcct gcccatcgac ggcgacacgc cgaccgatgc
    16441 cgccagtctg gaagcgggct atgccgccaa ggcgaaggca gaagcggcgc ggcagggtgc
    16501 gggaacaccc ggcagcgcct aaccataacc gttctacaca ggagaacagc atggctttag
    16561 acattatggc ggccttcacc aatgagccgc cagaacttga tttcatctgg cccggattct
    16621 tggccggaac cgtgggcgca cttgttgcac ctggcgcaac tggcaagagc ttttttgctc
    16681 ttgaagcggc catgtcaatc gcttgcagtg tggcaggcgg cgaccttgta ggactggccc
    16741 cggcgcacac cgggcgcgtg gtctatctcg ctggcgaaga tccacagccc gcccttgtgc
    16801 ggcgtgtcca cgccatcggc cagcacctca accagtcggc ccgcgaagcc atcgctgaga
    16861 acctgatgct tgagccgatc atgggcaagc ggttgaacgt gatggacgag gcgcacttgc
    16921 gccgcgtcat cgactacagc gcaggggcgc ggctgattgt gctggacaca ttgagccgca
    16981 ttcacagcct cgacgagaac agcaacggcg acatggccca ccttgtttcc gtgttggaac
    17041 acatcgcggc aaccaccggg gcggctgtcc tgtacctgca ccacgtcaac aagggcagcg
    17101 cccgcgacgg ccagaccgac cagcagcagg cagcgcgggg cgcgtctgcc ctgatcgaca
    17161 acgccagatg gtgcggctat gtcgccaaga tgacggagca ggaagccgag cgcctgagcg
    17221 accggggctt tgatcgtgcg cccatcggca acgagcggcg cggccttttt gtccgctttg
    17281 gcgtgagtaa gcagaactac gacgcgaccc cgctagaccg ctggtatcag cgacacaccg
    17341 gcggggtgtt gctgccggta gagctacagg agatcaagcg tgagagcggc aacaaggggg
    17401 gcaagggcta tgactcagca gcgtattaaa ccggcctatg ccaaattcga tcccgctcat
    17461 gtgtttgacg ggcttttcgt ccccacgaag gggaagaagc gcgggcgact gtatgtgccg
    17521 ccgcgccgct tcggcgatag tgaaatcagc tttcaagggt tcgagcagct tggagctgat
    17581 gaccaatcaa tcttgcttgc agtaagcgcc cagcttggca ttgacggctt gatgatcgag
    17641 gcaaaaccac ccggcgaaat aggccagcaa ttgcgccttg ctttggactt tgacaacgat
    17701 gatggaaggc cgctgaaaac caagaaaacc agtttgcgca gcctgctgat tgatgctgga
    17761 tatgacgacc cagaaagcgg ggcggcactt gccagaatca aggaaagcct gaaccgaatg
    17821 ggtaacgcgc agatacggga aatcaatcac gctaccggct gggattaccg ctgcaatctc
    17881 ctttcgagtc ggttcaatca caagactggg gaaatctttg ttgccgtcaa tccgcgcctg
    17941 accggggcgg tttttcgaga gcaacacgtc aaggtttcgc ttttcgagcg caacgagctg
    18001 gagagtgaag ccgccaagct gctgcactgt tggctgtgct caaacatccg gcttggccgt
    18061 tcgcttggca atggcaacgg ggcgcacatc gacacgctag cgccccacgt atggggcaag
    18121 gcggcgtggg aagaagcatc aacgaaggtt cgatcagtca ggcggggtca actacgcgat
    18181 gctttagacg aaatctcaga ccgcacacgc ggactgcaag gcggtatggg atgggccatc
    18241 gaccagacca gcagcgggct tgtgctggta agtcgtccca aggaactgcc gttccttgag
    18301 ggtgagcacg acatgcgccc cagcgaatac cacgacctca tgagccagcc gccaatgcaa
    18361 gaaccagatt tgttcgaccc gcaggactgg acgccggact gagccgcacc tggtgaacta
    18421 ctcgctgcta aagcggtcga gcttccaaac taacctaagc ggccagcttt tcttttttga
    18481 cgcttcgttg agcactgctg gttgagcttt tggctcggcc agtcttacga ttgcctccac
    18541 gtccactatc cgactgagtt cgcagaaccc catcgccaga taacaccgtt ccagtgtcca
    18601 aaattaagtt aattgcccgc ttcttgataa ccagtgatgc attgtgatct gcattgtcag
    18661 tatttccaca attaccgcaa acaaacaggg cttgtgtttt gcgattgtcg ggatgagtgt
    18721 gaccgcattt tgcgcactcc tgactggttg ttggtgcggg tattttaaat accgctttgc
    18781 tggatgaata agccttgtag taggtgtaag tctcgatcac atgccagccc acattaagaa
    18841 tagacttatt cagtcctgct ttctgcttgg ctttatttga tatgaatcga ccttgttcat
    18901 cctgttttgc tttcggcctt ctcgtcatcc ttgcggttcg taacgcctca aacacaatga
    18961 ttttggcgct gctatcaacc aataaccgac tggtcttatg cgcaaaatca tttcgtatgt
    19021 tagccttttt agcatgatga accgcaattc gatgcttggt cttggctctg cggttagagc
    19081 ctttttgctg ccttgccagt ttgcgctgca atcgcttgat atagcggtct gctttgctca
    19141 tgttcttttt ctggctatgg gtgaaatcat aggtttgttc gccagcacaa acggggatcg
    19201 ccacgcctcg gtcaacaccc atggtgtgct cttccagata ttctctggtc gccccttgca
    19261 gaaaagctaa gtgctcttca ttggtactta gtttgcgatc aggctgtcct tgctcatagc
    19321 agaatgacac ataatagtgg ccgcgctctt ttctcacata aagcgagttt gggatctcaa
    19381 atttgccatg tgccttaaag gacagataac cgatattgtt ggtctttgtc ccaataaaca
    19441 ggcgcacgtt gccgtcatcg caatggtcga aacggaacac ttcacgggta agataaatgc
    19501 ttcctttgtc cgttttaggt tttcgctttg gcctgccgca tttcccgctc atgaatttct
    19561 gataagtttg ataccagtta accgcgctat tacgcaagat ttgactaggg cattcactta
    19621 gccacggaga aagctctttg gatttgaatt gtgaagtggt ctggtcgatg ggcgcgtaag
    19681 ttccgatggt gcaatattta cgggcatagg ttcggtaata acgctcttct tctaccttgg
    19741 cattccagat actacgagcg caccccatcc actgactcaa gatcagtttt tggtgagatg
    19801 tcgggttagc gcgtagcttg atgccagtta acatgatgtc cgtttatttg ctatttacac
    19861 ctgaaattat tacacttact taaactttgt caatctagca tgtggttata atgtacgatt
    19921 ggagaacagg tagaagctgc atttttaaaa acaacgttca tctagtcttt gttacaaagt
    19981 atcgtcgtgg tgtttttacc aaagaaatgc ttgaacggac tgaggcaata atgaaagaga
    20041 cttgtgagca gatggattgt gagctactgg agtttggtgg agaggacgat cacatccata
    20101 tgatggtgtc cgtacatcca aaattggcaa tctcaaattt agtcagcaag ttaaaaggta
    20161 aatcgtctta catgatccgg cgagagtatt gggacagggt aaaaacaatg ctttggggca
    20221 accatttctg gtcgccaagc tactgtgtgg tttcttgcgg aggggttgcc ctcgatgttg
    20281 ttcgggagta catcaacaac cagaacgaac cgcccagcga aaaagccatg aagacatcac
    20341 aagcgttgaa gcaaagaaaa gagtagaaac cacttgcttg actcgcccct aaaggagcga
    20401 gattgcgcaa gcactccgtt caagaccgcc gatgatgaga gccaggcctc gctcgaatgc
    20461 cgcgtccgga ccgccttcgt agacgatttt catcgcgctc tgtaggcgcg ccggcatcgt
    20521 agacgctgag gtggtcaact gatcttcgcc ccgctcctcg gcgtctgcct cgctagcttg
    20581 ctgctcaaga acagcgccga cggtgaagta gctgattgcc atcaacgcat aggtcgcgtc
    20641 acctgccgaa aagccagcat cgcaaaggaa gcgaagctgc gcgtcggctt tttccatctg
    20701 cggcgcggct ggccgcgtcc cggcatgaat acgcgcgcca tcgcgataag cgagcaacgc
    20761 ccgtcgaaaa ctgcatgcat tgcccttcag gaacgaacgc cagtcgtcgt catcccttgg
    20821 cgtcgaatgc gtgtgattta tcgtcagcat ggcttcggca agtgcgtcga gcaacgcacg
    20881 cttgttcttg aaatgccagt agagcgctgg ctgttgcacc ccgaggcgct cagccagtcg
    20941 gcgcgtcgtt agaccttcca tgcccacgtc gttaagcagt tcgagcgcgg ttcggatcac
    21001 ggcctcgcgt tggagcttgt tcattcgcga attctcatgt ttgacagctt atcatcgata
    21061 agctttaatg cggtagttta tcacagttaa attgctaacg cagtcaggca ccgtgtatga
    21121 aatctaacaa tgcgctcatc gtcatcctcg gcaccgtcac cctggatgct gtaggcatag
    21181 gcttggttat gccggtactg ccgggcctct tgcgggatat cgtccattcc gacagcatcg
    21241 ccagtcacta tggcgtgctg ctagcgctat atgcgttgat gcaatttcta tgcgcacccg
    21301 ttctcggagc actgtccgac cgctttggcc gccgcccagt cctgctcgct tcgctacttg
    21361 gagccactat cgactacgcg atcatggcga ccacacccgt cctgtggatc ctctacgccg
    21421 gacgcatcgt ggccggcatc accggcgcca caggtgcggt tgctggcgcc tatatcgccg
    21481 acatcaccga tggggaagat cgggctcgcc acttcgggct catgagcgct tgtttcggcg
    21541 tgggtatggt ggcaggcccc gtggccgggg gactgttggg cgccatctcc ttgcatgcac
    21601 cattccttgc ggcggcggtg ctcaacggcc tcaacctact actgggctgc ttcctaatgc
    21661 aggagtcgca taagggagag cgtcgaccga tgcccttgag agccttcaac ccagtcagct
    21721 ccttccggtg ggcgcggggc atgactatcg tcgccgcact tatgactgtc ttctttatca
    21781 tgcaactcgt aggacaggtg ccggcagcgc tctgggtcat tttcggcgag gaccgctttc
    21841 gctggagcgc gacgatgatc ggcctgtcgc ttgcggtatt cggaatcttg cacgccctcg
    21901 ctcaagcctt cgtcactggt cccgccacca aacgtttcgg cgagaagcag gccattatcg
    21961 ccggcatggc ggccgacgcg ctgggctacg tcttgctggc gttcgcgacg cgaggctgga
    22021 tggccttccc cattatgatt cttctcgctt ccggcggcat cgggatgccc gcgttgcagg
    22081 ccatgctgtc caggcaggta gatgacgacc atcagggaca gcttcaagga tcgctcgcgg
    22141 ctcttaccag cctaacttcg atcattggac cgctgatctt cacggcgatt tatgccgcct
    22201 cggcgagcac atggaacggg ttggcatgga ttgtaggcgc cgccctatac cttgtctgcc
    22261 tccccgcgtt gcgtcgcggt gcatggagcc gggccacctc gacctgaatg gaagccggcg
    22321 gcacctcgct aacggattca ccactccaag aattggagcc aatcaattct tgcggagaac
    22381 tgtgaatgcg caaaccaacc cttggcagaa catatccatc gcgtccgcca tctccagcag
    22441 ccgcacgcgg cgcatctcgg gcagcgttgg gtcctggcca cgggtgcgca tgatcgtgct
    22501 cctgtcgttg aggacccggc taggctggcg gggttgcctt actggttagc agaatgaatc
    22561 accgatacgc gagcgaacgt gaagcgactg ctgctgcaaa acgtctgcga cctgagcaac
    22621 aacatgaatg gtcttcggtt tccgtgtttc gtaaagtctg gaaacgcgga agtcccctac
    22681 gtgctgctga agttgcccgc aacagagagt ggaaccaacc ggtgatacca cgatactatg
    22741 actgagagtc aacgccatga gcggcctcat ttcttattct gagttacaac agtccgcacc
    22801 gctgccggta gctattgact atccggctgc actagccctg cgtcagatgg ctctgatcca
    22861 aggcaaactg ccaaaatatc tgctggcacc ggaagtcagc gccctgcacc attatgttcc
    22921 ggatctgcat cgcaggatgc tgctggctac cctgtggaac acctacatct gtattaacga
    22981 agcgctggca ttgaccctga gtgatttttc tctggtgccg ccctatccct ttgtgcagct
    23041 tgccacgctc aaaggggttt gaggtccaac cgtacgaaaa cgtacggtaa gaggaaaatt
    23101 atcgtctgaa aaatcgatta gtagacaaga aagtccgtta agtgccaatt ttcgattaaa
    23161 aagacaccgt tttgatggcg ttttccaatg tacattatgt ttcgatatat cagacagtta
    23221 cttcactaac gtacgttttc gttctattgg ccttcagacc cctacaccga ctttgccatg
    23281 tcacatgccc gtttgcttgg ttttgatctt tgcccgcggt tgaaggaact caaacagcgc
    23341 cacctctttg tgccacgcgg caccaaagtg cccgcagaaa tcgctgcggt gtgcgaagcc
    23401 aatgtcgacg tcgctttgat cgaaaagcat tgggatagtc tggtgcacct ggcagcctcg
    23461 gtcatgagcg gacatgccag tgcggtggca gctcttgcgc ggttcggttc tgccgcccag
    23521 ggcgatccaa tctatgaggc tggcgtgcaa ttggggcggt tgctgcgtac ggcgtttttg
    23581 gctgactact ttgtcaagga cgctttcagg aacgagttgc gccgggtgct caatcggggc
    23641 gaggctgtta acgccctcaa gcgcgccatt tataccggcc ggatcagccc ggcgcaggcc
    23701 aaacgtgtcg atgaaatgca ggctgtggcc gatgcgttga gcctgatggc caacatcgtg
    23761 atggcgtgga atacctcaca gatgcaggcg gtcctggatc gctggtcgaa ccgccgccag
    23821 gtcattccac cggaactgat cgggaagatt gcgcccacca ggctggagag catcaacttg
    23881 cggggtgtgt ttcgcttccc ggttgaccgc tatgctgacc aaatcctgcc ttcgcggcca
    23941 aatgcatcga taactggcac caatggatga aaccgaccac ggtttgacgc cacgaatcgc
    24001 agatttgaaa gtgaacagga aagtcaatga aatcaacgat ctaccaacac cacctccgcg
    24061 ccagtgctag cttttcgtac cgtcacttat tgcactgaaa acgaggagac cccgggcaag
    24121 aacaccaatg tgtacctggg ctcagccgaa ctctcggcca tctgctccaa gctgggccgt
    24181 attcccagca aggaagaata tctggccgac gtgggcgtca ttaaccagag cagcgacaag
    24241 atctaccagt acctgaactt cgaccagatc gaagaatatg tggagaacgc caaggaagcg
    24301 actgcctgag cggcgatggc tccctgaaac aacaaacggc ccttcggggc cgttttgctg
    24361 cgtagcctgg ctgaggagaa gtctgcagaa tgctgtgtat ttacacagta tttatgccag
    24421 ccacctccaa gcccaagctc tacaacccgc gccaccccga gcgcacgctg ctctaccaaa
    24481 cggtggccga gcattacgag acctggcttg atctggccag cgccggccag ttcgacggcc
    24541 agggcgacca ccgcagcccc aagccctatg tgcgccaagc gtttgccaag tacctggaat
    24601 gcggcatctt tgcccacggc tttgcccgtg cccgctgcga cgactgcgga cacgactttc
    24661 tggtggcctt ttcctgcaaa ggccggggcg tctgcccctc gtgcaccacg cggcgcatgg
    24721 ccgagacagc ggcacacctc accgaccacg tcttcccccg cctgccagtg cgccagtggg
    24781 tgctgtcggt tcccaagcgg ctgcgctact ttatgcaacg cgacagcgtg gtgctgggca
    24841 tggtgttgcg catcttcttg cgcgtcattg agcaaaccct gcaagccaac agcccatgcg
    24901 cagcgcatgc gaacaaggcc gccctgcaca tcggtgcagt cgccttcatt caccgctttg
    24961 gctccagcct gaacgagcat gtgcatttcc atgtgtgcgt ggtcgatggc atgtttgagg
    25021 cggtggcagg ggaggcgagt gagcagggca cccgcaccac agcgatcagc gtcatgtttc
    25081 acccggctat cggcatcgac cccgaagcgg tgacccaagc ccaggccagt ttgcgtcggc
    25141 gcatcctgcg cgcctttgtg ggccggggcc tgctcgaagg cttcgaggcc caggagatgc
    25201 tggggtacaa acacagtggg ttttcggtag acaccagcgt gtgcatagca gcacaagacc
    25261 gagcgggcct ggagcgcctg ctgcgctact gcgcacggcc cccgtttgcg ctggataggc
    25321 tgcgcaaagc gggcagtgag ctcatttacc gctgcgccaa gcagcacagc gagcctggca
    25381 gtgaccggcg cgaccaacgc aaggcaaagc gaggtgttcg ggccgacgaa ctgcacctca
    25441 cgccgctcga actcatcgac cgccttgccg cgctggtgcc gccaccgcgt gcgcaccgcc
    25501 accggtacta cggcgtgctg gcgcccaatt cacccctgcg ggctgcggcg gttgcactgg
    25561 gcgcaggcca aaccgcaggc gcgggcacgg gcacggcaca gcccgagcca ggcggtgtga
    25621 ccgcagcggt ggatgccatg ggagtggcca cggtcggtgg tcccagccag cccgagccca
    25681 cccagccagc tctgcccaaa cgctcagctc acattctgtg ggcggtgctg atcgcccgca
    25741 tctacgaggt gttgccgctg ttgtgcccgc tctgcggtgg ccagatgcgc atcatcgctt
    25801 tcatcaccta cagtgccgac ctccggcaca tcctggagca catcggggtg gagacagagc
    25861 cgcctcgcat cgcgccagca cgcgggccgc cgctgtggga tgggtgcgat gtgccgatgg
    25921 gcgatggtgt cgaggttgag ccagattggg gcgaggcggc ccaaccggcg ccggactttg
    25981 aggtcgatca gcgcgtcagt tggtaaggga aggcagcagc ggtttggccg cgcggcaggg
    26041 ctgcgtctgt cactgccaaa aaatgtgcaa accgaaaaat ctcgggctac tggcgctgat
    26101 caagcgctca ggcaggctca gcctgaaggc ctgtgatgcc caaaacctgg gccataatcg
    26161 tcctcctgtg gttggatttc ctatccgcaa gcttaaagag ttactgacga agaaaggtgc
    26221 aaaagtatta atgacccgtg aaatagatga ttcactagat gatcatatac cgaataatgg
    26281 aagccgtcat cgtgaagatt taaattcaag agtaaagatt gttaataaca gtaaagtaga
    26341 tatcttgtta agtattcatg taaaccataa taaaaatgca aataaaatag gacctataat
    26401 cttttacaat acaagtagtg aagaaagcaa gtattttgca aatcatatac aagagtattt
    26461 aaataatctt tcgtcatata aggaaataga tatagggact aagcataaag caacaccagg
    26521 agactattat cttttgcgaa atatctcacc accaggagta attattgaaa tggggtttat
    26581 ctcaaatgaa agtgatagga ggcttctatt ggataataaa catctagatg aaattgtaga
    26641 actaatcaca aagggtatta tcgattactt taatgcagat cgttaataac acttaaaaag
    26701 aaattcacag aatgttttct gctaacaaca ttaaaattgc tagatgctta cagtaaattc
    26761 gataatcagc ctgtacaaga agtgatttaa tgccatgttc atcaatattc ttataaaaca
    26821 atttatgcaa ataaaggatg tttttctccg taatttcttt attcccaagg aaagtaaaca
    26881 tataatcata taagaatcta ttttcttgaa gtattattta ttaattgtta taatcaactc
    26941 aacgagatta aattgatgcg aggtgaaaaa cgatgttcta catcagatat ccttgttaat
    27001 ttgcgattaa ggcaaaggca cgaagtcctc caggttaatt tgattacatg tctaaaatta
    27061 aaaaaatgga ggaatttaaa tgcaaattat aaatatgact caagtaaata aaacacaact
    27121 aatccaagca gcccaaatat tgactgatag tattccaatt ggttggccaa cacttcatga
    27181 cgctatggat gaaataaagg agcgcttgat tccagaaaac acattacttg ctgctattga
    27241 aaatgatatt gtaatcggtt ggggcggtat acttgcaccc atgtataatg gaaatgtatt
    27301 cgaactacat ccgttagctg ttcgcagtga caagcgaaat ctaggtattg ggaggacaat
    27361 cgtaacagct cttgaggatg aagcaagaaa gcaaggtggc ttgacaatac atttgggtgc
    27421 tgacgatgaa ggaggcgatg gggaaacatc ttttgcaaat gttgatttgt atgatgattt
    27481 accaggaaaa ataaacaact tcaatgccgg cactcatcaa tctggattct acttaaagct
    27541 cggatataag attatcggag ttatgcctga cgcaaacgga ataggaaaac cggatattta
    27601 tttcggcaaa ggattataaa aaggatagaa ttgtatattc cattagtaag agttaaggat
    27661 atctaaactt gtaaagggca agttagattt ctagctatga caaataaata agtatttaaa
    27721 agtaaacagc ttaaaggatt gagtttcatc ctttaagctg ttattattaa aactctgttt
    27781 tctatagatt ttctataaaa atttaattat cctctttatt ttcgattagt aaaaatcctg
    27841 actttttcaa aggggatatt atagaattat aaataagact aactaatatt acagatacta
    27901 cagcatttat aaatgtagtt actgcactta actttgctag tattgatgct agttcttgtg
    27961 gttgccctag aatatatagt ttgtaaaagt atcctacaat aggatcaaaa ataacattaa
    28021 aagttaatcc acatattgaa gaaataagaa cccatttaaa tacataaccc ttattattgc
    28081 tatggtttat tttagcaaaa ttatgagcaa ctaaccctgt tattaagcca atacatagtt
    28141 ttaatacaaa tgtcttcggt gctacagtaa tgtatacag
//
