LOCUS       NZ_AP018745            51983 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Escherichia coli strain MRY14-225 plasmid pMRY14-225ECO_3, complete
            sequence.
ACCESSION   NZ_AP018745
VERSION     NZ_AP018745.1
DBLINK      BioProject: PRJNA224116
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Yamagishi,T., Matsui,M., Sekizuka,T., Ito,H., Fukusumi,M.,
            Uehira,T., Tsubokura,M., Ogawa,Y., Miyamoto,A., Nakamori,S.,
            Tawa,A., Yoshimura,T., Yoshida,H., Hirokawa,H., Suzuki,S.,
            Matsui,T., Shibayama,K., Kuroda,M. and Oishi,K.
  TITLE     A prolonged multispecies outbreak of IMP-6 carbapenemase-producing
            Enterobacterales due to horizontal transmission of the IncN plasmid
  JOURNAL   Sci Rep 10 (1), 4139 (2020)
   PUBMED   32139745
  REMARK    DOI:10.1038/s41598-020-60659-2 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51983)
  AUTHORS   Sekizuka,T., Matsui,M., Yamashita,A., Kato,K., Suzuki,S. and
            Kuroda,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2018) Contact:Tsuyoshi Sekizuka National Institute
            of Infectious Diseases, Pathogen Genomics Center; 1-23-1 Toyama,
            Shinjuku-ku, Tokyo 162-8640, Japan
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015171415.1-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 05:10:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 66
            CDSs (total)                      :: 66
            Genes (coding)                    :: 57
            CDSs (with protein)               :: 57
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 9
            CDSs (without protein)            :: 9
            Pseudo Genes (ambiguous residues) :: 0 of 9
            Pseudo Genes (frameshifted)       :: 1 of 9
            Pseudo Genes (incomplete)         :: 8 of 9
            Pseudo Genes (internal stop)      :: 0 of 9
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP018745.1.
            Annotated by DFAST v.1.0.5 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..51983
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="MRY14-225"
                     /isolation_source="abdominal drain discharge (pus)"
                     /host="Homo sapines"
                     /db_xref="taxon:562"
                     /plasmid="pMRY14-225ECO_3"
                     /geo_loc_name="Japan:Osaka"
                     /collection_date="2013-10"
                     /note="Inc type: N; ST357"
     gene            101..820
                     /locus_tag="IST04_RS00005"
     CDS             101..820
                     /locus_tag="IST04_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561120.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001749982.1"
                     /translation="MDKLLNKKIKVKQSNELTEAAYYLSLKAKRVLWLCLMQTYFTASV
                     SEDDDEMAVLGDSTFKVKVADYEQIFQVSRNQAIKDVKEGVFELSRSAVIFYPKEGSFD
                     CVARPWLTEAGSRSARGIWEIEFNHKLLRYIYGLTNQFTTYSLRDCGSLRNPRTIRLYE
                     SLAQFKSSGLWVTTHAWLNDRFLLPESQQKNLAELKRSFLDPALKQINEKTPLLAKYSI
                     DDSGKFLFSIIDKQNPV"
                     /name="replication initiation protein"
     gene            complement(2517..3086)
                     /locus_tag="IST04_RS00010"
     CDS             complement(2517..3086)
                     /locus_tag="IST04_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749988.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001749988.1"
                     /translation="MKIGYARKSTHLQDVAHQVDELTKAGCEQIYQDQTSRSGPKRDKK
                     GAPELENCLKALREGDTLVVWALDRLGGSLGQVITLLDDLKKRGITFIAIKDRIDTNAP
                     VIGEIYTHLMAIFSSFERNRNIERTRSGLAAARARGRVGGRKPSLSEEDVKQIRILLAD
                     PEMTVGAVAKRFNVSRMTIYRYTTKS"
                     /name="recombinase family protein"
     gene            complement(3479..>4207)
                     /gene="intI1"
                     /locus_tag="IST04_RS00015"
                     /pseudo=""
     CDS             complement(3479..>4207)
                     /gene="intI1"
                     /locus_tag="IST04_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /name="intI1"
     gene            complement(4261..4965)
                     /locus_tag="IST04_RS00020"
     CDS             complement(4261..4965)
                     /locus_tag="IST04_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<5029..5169)
                     /locus_tag="IST04_RS00025"
                     /pseudo=""
     CDS             complement(<5029..5169)
                     /locus_tag="IST04_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006770492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(<5234..5524)
                     /gene="intI1"
                     /locus_tag="IST04_RS00030"
                     /pseudo=""
     CDS             complement(<5234..5524)
                     /gene="intI1"
                     /locus_tag="IST04_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /name="intI1"
     gene            5692..6246
                     /gene="aac(6')-Ib"
                     /locus_tag="IST04_RS00035"
     ARG             5693..6243
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6323..7063
                     /locus_tag="IST04_RS00040"
     CDS             6323..7063
                     /locus_tag="IST04_RS00040"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060614779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase IMP-6"
                     /protein_id="WP_032492096.1"
                     /translation="MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNG
                     WGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGI
                     EWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVV
                     VWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPGHSEVGDAS
                     LLKLTLEQAVKGLNESKKPSKPSN"
                     /name="subclass B1 metallo-beta-lactamase IMP-6"
     gene            7196..8034
                     /locus_tag="IST04_RS00045"
                     /pseudo=""
     CDS             7196..8034
                     /locus_tag="IST04_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
                     /name="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
     gene            8151..8498
                     /locus_tag="IST04_RS00050"
     CDS             8151..8498
                     /locus_tag="IST04_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            8492..9331
                     /gene="sul1"
                     /locus_tag="IST04_RS00055"
     ARG             8493..9328
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9459..9959
                     /locus_tag="IST04_RS00060"
     CDS             9459..9959
                     /locus_tag="IST04_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000376623.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGR
                     GVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLE
                     LEI"
                     /name="GNAT family N-acetyltransferase"
     gene            <10280..10348
                     /locus_tag="IST04_RS00065"
                     /pseudo=""
     CDS             <10280..10348
                     /locus_tag="IST04_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            10466..11230
                     /locus_tag="IST04_RS00070"
     CDS             10466..11230
                     /locus_tag="IST04_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="WP_001389365.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHT
                     TIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFY
                     LSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQ
                     VKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIR
                     GEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(11370..>11435)
                     /locus_tag="IST04_RS00075"
                     /pseudo=""
     CDS             complement(11370..>11435)
                     /locus_tag="IST04_RS00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            11491..12705
                     /locus_tag="IST04_RS00080"
     CDS             11491..12705
                     /locus_tag="IST04_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /protein_id="WP_004098817.1"
                     /translation="MLMSVFHNWLLEIACENYFVYIKRLSANDTGATGGHQVGLYIPSG
                     IVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRWGR
                     GSPLQDPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISG
                     PAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQLLDRR
                     RVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEH
                     GLRHFATQAITEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQILNEADK
                     IHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTGL
                     YADIP"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(12739..14172)
                     /locus_tag="IST04_RS00085"
     CDS             complement(12739..14172)
                     /locus_tag="IST04_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_001288432.1"
                     /translation="MSEFELLAQDLLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAEL
                     LRKVGKNEWSRETLNRWINGKCSPKTLTLAEEELLRKMLPEAPAHHPDYAFRFIDLFAG
                     IGGIRKGFETIGGQCVFTSEWNKEAVRTYKANWFNDAQEHTFNLDIREVTLSDKPEVPE
                     NDAYAYINEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARII
                     RAKKPAIFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFL
                     PQHRERIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEY
                     LYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFA
                     NEENQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKL
                     LEPYILKAVNADSCKVERI"
                     /name="DNA cytosine methyltransferase"
     gene            <14271..14543
                     /locus_tag="IST04_RS00090"
                     /pseudo=""
     CDS             <14271..14543
                     /locus_tag="IST04_RS00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(14554..14760)
                     /locus_tag="IST04_RS00095"
     CDS             complement(14554..14760)
                     /locus_tag="IST04_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749967.1"
                     /translation="MKSVTIEAKTFAEMLGITEGELIFAIKKTGTFKNKTIPQPHEPHK
                     SNNRFLYSDVMRFIESLKDKENR"
                     /name="hypothetical protein"
     gene            complement(14765..15412)
                     /locus_tag="IST04_RS00100"
     CDS             complement(14765..15412)
                     /locus_tag="IST04_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532074.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_015344958.1"
                     /translation="MTMIPFPTTENLILWACSAIALLAVVFFRRSVRHRRHKRKQQSAR
                     RVLERIKTLPGFPQKINYLRKIDPFVFEELLLEGFEAHGFRTIRNKRYTGDGGIDGQVI
                     IGKYRYLIQAKRYRGHIALQHVQEFEKLLKRHNCRGLFCHTGKTGAGSKSVSIASERME
                     IISGQRLIDLLTPGSSFTIATAPQTMMKRTAATLETSTIVKDAGKENRYHES"
                     /name="restriction endonuclease"
     gene            complement(15462..15695)
                     /locus_tag="IST04_RS00105"
     CDS             complement(15462..15695)
                     /locus_tag="IST04_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006118529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001191790.1"
                     /translation="MQSQLNNQQRQINELSVRLQSAESRLSKQEEKLRNELLQSSGYCY
                     LNGARYSTGTVLYGRICQNQSGSASWQVYSRR"
                     /name="hypothetical protein"
     gene            complement(15809..16123)
                     /locus_tag="IST04_RS00110"
     CDS             complement(15809..16123)
                     /locus_tag="IST04_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001749965.1"
                     /translation="MKKLLIPLIAAGSLLYIPASHAEDPCKVIMCMAGKLTGDSGGSEC
                     NSAEAAFFNIVKKNKHGFLPNHTKDARKAFLNECPDNGEGGSNQSMISQIISKYGKVRL
                     "
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(16120..16464)
                     /locus_tag="IST04_RS00115"
     CDS             complement(16120..16464)
                     /locus_tag="IST04_RS00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749964.1"
                     /translation="MGELIDFAERQKSRRKKKASSIPPIFRKFRVHAIRLLASIIKSGS
                     YSVAYIVKKITGKLIKFYTILTIFVFVVEYIAGDIGYKSIYNAALLLILLTVINILASV
                     YLNKLLRTKQ"
                     /name="hypothetical protein"
     gene            complement(16480..16851)
                     /locus_tag="IST04_RS00120"
     CDS             complement(16480..16851)
                     /locus_tag="IST04_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000960954.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_011867773.1"
                     /translation="MIRANEIVSRRNEKKTAEGRKVMLVPLKSEKRPKGEPVYRDPDNP
                     FNTWTGIGKRPAWLTAKLDAGISLEAMKMQGVANPREHRPAKYRDPRNAENTWSGTGRR
                     PTWLKELLDSGLSLDDLKI"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            16894..17628
                     /locus_tag="IST04_RS00125"
     CDS             16894..17628
                     /locus_tag="IST04_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_001749963.1"
                     /translation="MSKHPKLLVLALACLACAGRASAAPASDEVARLAQRCAPDVSPLT
                     MAYIVGHESSNGPYRININGSIQLKQQPRTEAEAVSVAKVLLKDNKSFDMGLAQINSNN
                     LVGLGLSVDDIFKPCINLRASQTILKACYDSALKSYPAGQVALRHALSCYNTGSLTNGI
                     SNGYVTKVINVARQSTDLKIPTLLPDGQTSEDSTATEPQQAKSTAPQYDGEQDVFGSGD
                     GDAFSRNNTDAFLTRQETAKGE"
                     /name="lytic transglycosylase domain-containing protein"
     gene            17637..17918
                     /gene="korA"
                     /locus_tag="IST04_RS00130"
     CDS             17637..17918
                     /gene="korA"
                     /locus_tag="IST04_RS00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor KorA"
                     /protein_id="WP_000440698.1"
                     /translation="MERLYLVLQSQILELFEAGKVKEVTIERVSLKKWYPVFQIDDEQL
                     GQIACSIRVNKEHELRTWADLRLLAEFLKDKCGVEECRLNLQSTEDSE"
                     /name="korA"
     gene            17928..18221
                     /locus_tag="IST04_RS00135"
     CDS             17928..18221
                     /locus_tag="IST04_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749962.1"
                     /translation="MTTLFKKYGPAVVMGVLSIALPQIALAAGTDTGESTATSIQTWLS
                     TWIPIGCAIAIMVSCFMWMLHVIPASFIPRIVISLIGIGSASFLVSLTGVGS"
                     /name="hypothetical protein"
     gene            18271..18588
                     /locus_tag="IST04_RS00140"
     CDS             18271..18588
                     /locus_tag="IST04_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000496058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_000496058.1"
                     /translation="MFVDGKRPLFKGATRLPRALGVPRNVAMMIFMISASLFMIIHMWA
                     ILVFVFLWIPSAALTKYDDRMFRIMGLWLKTKFSNWFDSPFKQWGGSSYSSVDYKRKGL
                     K"
                     /name="VirB3 family type IV secretion system protein"
     gene            18588..21188
                     /locus_tag="IST04_RS00145"
     CDS             18588..21188
                     /locus_tag="IST04_RS00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_001749961.1"
                     /translation="MRAATATKPKKIDAYRKEPSVNKKYLPYSYHLNDYVISMENGDLM
                     AFFKLDGRTHDCASDRELVTWHKDLNTLVKSFGTDHVELWTHEYHHEAKEYPDGEYDHF
                     FPAYVDQYNRKLHGDSKQLINDLYLTVIYKQVGDKTQKFLAKFEKPTRDEIQQMQNEAL
                     EGLEDISEQILEAMKPYGIQQLGIYYRDKRGVEIPAPDKKEREELAEVDESDIFDEAIV
                     IERNEPEPSQAHAYSKALEFLYFLANMEWAIVPVCRDRIREYIMDNRPVSSLWGDVVQI
                     RTVDHNFYTTGIEFREYEEDTEPGQLNMLKEADFEYLLTQSFSCLSESSAKTFLTHQEK
                     SLQETRDRAQSQLAQLGTALDMLTSREFVMGYHHGTVHVWDNDQNAVQRKARRVKVMLT
                     GCGVVGGTISLASEAAYYARLPGNQKWAPRPVPINSWNFLHFSPFHNFMRGKPDNNPWG
                     PALTMFRTISGTPLYFNFHVTPLEELSYGKRPLGHALITGMSGEGKTTLLNFLLAQSMK
                     YNPRLFVYDRDRGMEPFIRSVGGYYKVLQQGMPSGFAPLQIEPTKRNIALIKNLFRICV
                     ETTNNGPISATMATELAEGVDAVMGEGSLIPREARTVTILDGYVNEVVENGVSLKGLLR
                     EWTREGQYGWLFDNDKDSLDLSANDIFGFDLSEFIAAKEEVSSPARTPLMMYLLYRVRD
                     SIDGKRRVIQCFDEFHAYLDDPVIEREVKRGIKTDRKKDAIYVFATQEPNDALSSRIGR
                     TIMSQTVTKICLRDPEAIREDYAFLTDAEYDALMSITEHSRQFLVKQGQQSAIASFNLY
                     PRNSDDIDADIKTMDNVLSVLSGEPQNAEIAHELVERLGNDPEVWLKEYWRLTA"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            21206..21919
                     /locus_tag="IST04_RS00150"
     CDS             21206..21919
                     /locus_tag="IST04_RS00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001749960.1"
                     /translation="MKKTLTAVLLTTGLILGGAQSASAGIIVTNPTELAKQVEQLQQMA
                     QQLEQLKSQLQTQKNMYESMAKTTNLGDLLGTSTSTLANNLPDNWKEIYSDAMNSSSSV
                     TPSVNSMMGQFNAEVDDMTPSEAITYMNKKLAEKGAYDRVMAEKAYNNQMQELTDMQEL
                     TEQIKTTPDLKSIADLQARIQTSQGAIQGEQAKLNLMNMLQQSQDKLLRAQKERATHNF
                     VFGTGGDVTASPSIN"
                     /name="type IV secretion system protein"
     gene            21927..22154
                     /gene="eexN"
                     /locus_tag="IST04_RS00155"
     CDS             21927..22154
                     /gene="eexN"
                     /locus_tag="IST04_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncN-type entry exclusion lipoprotein EexN"
                     /protein_id="WP_001749959.1"
                     /translation="MKKLLLVIPFLLVACDASHDVEWYKKHEKERKATIQECKKDADEL
                     QKPDCKNAREADRQLFVFGKKDGEINSPKI"
                     /name="eexN"
     gene            22170..23210
                     /locus_tag="IST04_RS00160"
     CDS             22170..23210
                     /locus_tag="IST04_RS00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001749958.1"
                     /translation="MAFTLVADIFAKVDGAITSMVSANVATIISDVTPLIATCLTIKLM
                     VQGMYSAFNPGAGDSLSSLIKEYLSIALILSFATAGGWYQQELVNVALHLPDDFAGILS
                     APNKVGASGVPAIIDSGIEKGIKIVNTAWEAADVFSSSGLAAYAIGGIMMIATVVLGGL
                     GAGFVIMAKILLAVTLCFGPIAIFCLLWGATKNIFARWLASVINYGLVVVILALVFGFI
                     MQMFDNLLSSMNSDAAYSSITGSISALLLTVISVFVLFQIPQIAASWGSGISAGVADAA
                     RSTGSSMQALGNMGSHGMFGGNAFRGGNSGGGQQSAGGGSGSNSGGSSGSNLSGKARGS
                     RGKKAA"
                     /name="type IV secretion system protein"
     gene            23281..23439
                     /locus_tag="IST04_RS00165"
     CDS             23281..23439
                     /locus_tag="IST04_RS00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012561180.1"
                     /translation="MDAVMRSLLLMGVLLISACSSGHKPPPEPDWSNTVPVNKTIPVDT
                     QGGANES"
                     /name="hypothetical protein"
     gene            23429..24127
                     /locus_tag="IST04_RS00170"
     CDS             23429..24127
                     /locus_tag="IST04_RS00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004216210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000646594.1"
                     /translation="MKANKKTGLTREAIKEFNESRKGLEVDLMDEVLKSRRTAWMVATG
                     SAVVTVFALSLVGYVVHKYSQPIPAHLLTLNEATHEVQQVKLTRDQTSYGDEIDKFWLT
                     QYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINS
                     VILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRV
                     TSYRVNPEVN"
                     /name="type IV secretion system protein"
     gene            24138..25022
                     /locus_tag="IST04_RS00175"
     CDS             24138..25022
                     /locus_tag="IST04_RS00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_000735066.1"
                     /translation="MKKLLLSAVVLSVLGGAATNVMALEVGRNSPYDYRIKSVVYNPVN
                     VVKIDAIAGVATHIVVAPDETYITHAFGDSESWTFAHKMNHFFVKPKQAMSDTNLVIVT
                     DKRTYNIVLHFIGEETKKNADGTVSKSFIETPWAVRQAVLQLTYEYPFEQQEKAKSAAD
                     KKRITQKLKQTAFAGAKNYQYVMSEQPEMRSIQPVHVWDNYRFTRFEFPANAELPQVYM
                     ISASGKETLPNSHVVGENRNIIEVETVAKEWRIRLGDKVVGVRNNNFAPGAGAVATGTA
                     SPDVRRVQIGEDN"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            25022..26182
                     /gene="virB10"
                     /locus_tag="IST04_RS00180"
     CDS             25022..26182
                     /gene="virB10"
                     /locus_tag="IST04_RS00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB10"
                     /protein_id="WP_000101710.1"
                     /translation="MARKSVDVDQELDENTGDGEFESERGGFKGSNRRSAPGMKAFVIL
                     MALLALVFIGITVMGKIRTPAKAEADKDGGKAQQANTLPNYSFNSDPDVNKPATAQNSA
                     TDARAVQAAAQADADAGSSNTAARTSNKRKEPSPEELAMQRRLGGELAQTNQAATSNSP
                     GVQPQDNETSEGSSALAKNLTPARLKASRAGVMANPSLTVPKGKMIPCGTGTELDTTVP
                     GQVSCRVSQDVYSADGLVRLIDKGSWVDGQITGGIKDGQARVFVLWERIRNDQDGTIVN
                     IDSAGTNSLGSAGIPGQVDTHMWERLRGAIMISLFSDTLTALVNQTQSNNIQYNSTENS
                     GEQLASEALRSYMSIPPTLYDQQGDAVSIFVARDLDFSGVYTLADN"
                     /name="virB10"
     gene            26224..27219
                     /locus_tag="IST04_RS00185"
     CDS             26224..27219
                     /locus_tag="IST04_RS00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_000128596.1"
                     /translation="MTDAAFYQLGPLREYLEDPTVFEIRINCFQEVICDTFSGRRVVQN
                     AAITADFIRNLAKSLVSSNKLTMQAINDVILPGGIRGVICLPPAVIDGTTAVAFRKDLA
                     ADKNLEQLTSEGIFSDCRKITGSKQSLTDDDFFLKELHSSEKWPAFLQTAVEKKRTIVI
                     CGETGSGKTVLTRALLKSLHKDERVIILEDVHEVTVDHVVEAVYMMYGDAGKIGRVSAT
                     DALRACMRLTPGRIIMTELRDDAAWDYLKALNTGHPGGVMSTHANSARDAFNRIGLLIK
                     ATPIGRMLDMSDIMRMLYSTIDVVVHMEKRKIKEIYFDPEYKMQCVNGSL"
                     /name="ATPase, T2SS/T4P/T4SS family"
     gene            27219..27752
                     /locus_tag="IST04_RS00190"
     CDS             27219..27752
                     /locus_tag="IST04_RS00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="WP_000792636.1"
                     /translation="MKNLATWLLAAAFTTAALPAFAVEPSVQVGYSPEGSARVLVLSAI
                     DSAKTSIRMMAYSFTAPDIMKALVAAKKRGVDVKIVIDERGNTGRASIAAMNYIANSGI
                     PLRTDSDFPIQHDKVIIVDNVTVETGSFNFTKAAETKNSENAVVIWNMPKLAESFLEHW
                     QDRWNRGRDYRSSY"
                     /name="phospholipase D family protein"
     gene            complement(27926..28378)
                     /locus_tag="IST04_RS00335"
     CDS             complement(27926..28378)
                     /locus_tag="IST04_RS00335"
                     /inference="COORDINATES: protein motif:HMM:NF042748.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6710 family protein"
                     /protein_id="WP_001749956.1"
                     /translation="MNEREFFFTKIIWAMDYTHMKSLRLAAEDFPLALATAKILPWPWD
                     ESSYRSALADIGSAKGNPWVQDINHRVTLWLPWRIGFVRGGNHSIASGVLAGEGEVIPD
                     TVYDMRYLLDIVSTDGYYWYMSGKICERVSDYRTAAFFEIGRLLTL"
                     /name="DUF6710 family protein"
     gene            28689..28931
                     /locus_tag="IST04_RS00200"
     CDS             28689..28931
                     /locus_tag="IST04_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(28963..29613)
                     /gene="tetR(A)"
                     /locus_tag="IST04_RS00205"
     CDS             complement(28963..29613)
                     /gene="tetR(A)"
                     /locus_tag="IST04_RS00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_000164043.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            29719..30918
                     /gene="tet(A)"
                     /locus_tag="IST04_RS00210"
     ARG             29720..30915
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="99.75"
                     /coverage="100.0"
     gene            complement(30950..>31603)
                     /locus_tag="IST04_RS00215"
                     /pseudo=""
     CDS             complement(30950..>31603)
                     /locus_tag="IST04_RS00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058717.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /name="EamA family transporter"
     gene            complement(31798..31971)
                     /locus_tag="IST04_RS00220"
     CDS             complement(31798..31971)
                     /locus_tag="IST04_RS00220"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749978.1"
                     /translation="MEQTDKRKQDKLKFDRVINLARRLPQPAIHDLLRALILPIQADYL
                     LGSSQNSENKAR"
                     /name="hypothetical protein"
     gene            complement(31971..35213)
                     /gene="mobF"
                     /locus_tag="IST04_RS00225"
     CDS             complement(31971..35213)
                     /gene="mobF"
                     /locus_tag="IST04_RS00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884352.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobF family relaxase"
                     /protein_id="WP_001749977.1"
                     /translation="MLDITTITRQNVTSVVGYYSDAKDDYYSKDSSFTSWQGTGAEALG
                     LSGDVESARFKELLVGEIDTFTHMQRHVGDAKKERLGYDLTFSAPKGVSMQALIHGDKT
                     IIEAHEKAVAAAVREAEKLAQARTTRQGKSVTQNTNNLVVATFRHETSRALDPDLHTHA
                     FVMNMTQREDGQWRALKNDELMRNKMHLGDVYKQELALELTKAGYELRYNSKNNTFDMA
                     HFSDEQIRAFSRRSEQIEKGLAAMGLTRETADAQTKSRVSMATREKKTEHSREEIHQEW
                     ASRAKTLGIDFDNREWQGHGKPLEADIARNMAPDFTSPEVKADRAIQFAVKSLSERDAS
                     FERQKLIQIANKQVLGHATIADVEKAYLKAVQKGAIIEGEARYQSTLKVGASVMAETLT
                     RKEWIDSLTNSGMRADKARFAVDDGIKNGRLKKTSHRVTTVEGIRLERSILTIESRGRG
                     QMPRQLTAEIAGQLLAGKTLKKEQMRAVTEIVTSKDRFVAAHGYAGTGKSYMTMAAKEL
                     LESQGLKVTALAPYGTQKKALEDDGLPARTVAAFLKAKDKKLDEKSVVFIDEAGVIPAR
                     QMKQLMEVIEKHNARAVFLGDTSQTKAVEAGKPFEQLIKAGMQTSYMKDIQRQKNEVLL
                     EAVKYAAEGNAARALKNITGVNELKEEAPRLSQLADRYLSLSSEQQDATLIISGTNASR
                     KTLNDYIRGNLGLAGTGETFTLLDRVDSTQAERRDSRYFSKGQIIIPEQDYKNGMKRGE
                     SYQVLDTGPGNKLTVESSSGEQIAFSPRTHTKLSVYQAVSAELAPGDKVMVTRNDKTLD
                     VANGDRFTVKTVEGEKLTLEDKKGRTVELDKKQASYLSYAYATTVHKSQGLTCDRVLFN
                     IDTKSLTTSKDVFYVGISRARHEVEIFTDDKKSLASSVSRDSPKTTAAEIDRFFGLEAR
                     FKDIGRDTSLETRSAEKGLPEATGESMAFNQKPDEHNMTTGTDYQPVSNAEDAFHLKQN
                     PMDDSVGLRRHEAQQNDAELAHDYAAADDQQWSAQEYADYEHYAEASDYDFDSSIYDDY
                     AMPQTSQAEQSHTGKEHTHEHEHEHEEGGHEI"
                     /name="mobF"
     gene            complement(35213..36742)
                     /locus_tag="IST04_RS00230"
     CDS             complement(35213..36742)
                     /locus_tag="IST04_RS00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="WP_001749976.1"
                     /translation="MDDRERGLAFLFAITLPPVMVWFLVAKFTYGIDPSTAKYLIPYLV
                     KNTFSLWPLWSALIAGWFIGVGGLIAFIIYDKSRVFKGERFKKIYRGTELVSARTLADK
                     TRERGVNQLTVANIPIPTYAENLHFSIAGTTGTGKTTIFNELLFKSIIRGGKNIALDPN
                     GGFLKNFYRPGDVILNAYDKRTEGWVFFNEIRRSYDYERLVNSIVQESPDMATEEWFGY
                     GRLIFSEVSKKLHSLYSTVTMEEVIHWACNVDQKKLKEFLMGTPAEAIFSGSEKAVGSA
                     RFVLSKNLAPHLKMPEGNFSLRDWLDDGKPGTLFITWQEEMKRSLNPLISCWLDSIFSI
                     VLGMGEKESRINVFIDELESLQFLPNLNDALTKGRKSGLCVYAGYQTYSQLVKVYGRDM
                     AQTILANMRSNIVLGGSRLGDETLDQMSRSLGEIEGEVERKESDPQKPWIVRKRRDVKV
                     VRAVTPTEISMLPNLTGYLALPGDMPVAKFKAKHVKYHRKNPVPGIELRDI"
                     /name="type IV secretion system DNA-binding
                     domain-containing protein"
     gene            complement(36744..37160)
                     /locus_tag="IST04_RS00235"
     CDS             complement(36744..37160)
                     /locus_tag="IST04_RS00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749975.1"
                     /translation="MPIITAKVSDELLAYIDLVSGGNRSDYLRRCIEAGPGDRESGLKI
                     VADRLSDVNRKLDYLFDRASDADFGPLRDELKAITETLSGVKFPPAGQMMLHESLAIET
                     LILLRSIAEPGKTKAAKAEVERNGYKVWEPKKER"
                     /name="hypothetical protein"
     gene            37651..38070
                     /gene="stbA"
                     /locus_tag="IST04_RS00340"
     CDS             37651..38070
                     /gene="stbA"
                     /locus_tag="IST04_RS00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001749974.1"
                     /translation="MKPKSIRAALQLMLPEIEEMLSLGVSREEIYKAVSERFGLEGVNV
                     RSFDTSLYRARQIRKNGMHNTHERMPNNDDSVLHNTQKGGSEKGAEESVLHNTQTPPEP
                     EPQGSEKKESPGIIDKEFFNKISEDFDPKMFNKKF"
                     /name="stbA"
     gene            38079..38795
                     /gene="stbB"
                     /locus_tag="IST04_RS00245"
     CDS             38079..38795
                     /gene="stbB"
                     /locus_tag="IST04_RS00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StbB family protein"
                     /protein_id="WP_001749973.1"
                     /translation="MKVAVINYSGSVGKTLISSYLLAPRLTGAKFYAVETINQSASDLG
                     IENVSIFKGDDFSRLIEDIVFEDAGIIDIGASNVEAFLMAMSRFDSGANEFDKYVIPVT
                     PDNKAIDESLKTAHTLSKAGVSSDKIIFVPNRISPDSEVEDVLAPVFEFVKRTKVGKIS
                     KKSVIYNSEVFEYLAYHRISFEALTAEDPEEFKARAKQTTDADERKKLARRYTYMKQAI
                     PVKANLDKAYAALMGE"
                     /name="stbB"
     gene            38797..39165
                     /gene="stbC"
                     /locus_tag="IST04_RS00250"
     CDS             38797..39165
                     /gene="stbC"
                     /locus_tag="IST04_RS00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbC"
                     /protein_id="WP_000414913.1"
                     /translation="MEKQPDKFEVLMDWFLGDAKEITASQKEMTEILSALSEKLAKDTE
                     SLGETADSLKRTLVENQRSISLAISDDAKAREEFLTKFRRAQASRAETLTRQILFITAG
                     CTIVGAAVGAAIAIILLR"
                     /name="stbC"
     gene            39347..39691
                     /locus_tag="IST04_RS00255"
     CDS             39347..39691
                     /locus_tag="IST04_RS00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000999874.1"
                     /translation="MNDRQREQARIRQARRRARLKEEGASVTVTLTKQEEAMLQELCRV
                     RRPGRTAYSTNEFFQLLLIRNWQQWQEQKAQLGKCQACGKLKAEGGCGGERQSETFNCW
                     LAVEANELNV"
                     /name="hypothetical protein"
     gene            complement(39802..40122)
                     /gene="ccgAII"
                     /locus_tag="IST04_RS00260"
     CDS             complement(39802..40122)
                     /gene="ccgAII"
                     /locus_tag="IST04_RS00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgAII"
                     /protein_id="WP_001749971.1"
                     /translation="MTTQTLEQTLEDFRRQCESFAREQQPRCGLIYELYQRRLSAVIDG
                     YLAGVPAEYREELIAVARREFDYLTQDEIAEEIRQDRENDYCSHGIERNCCPLGCGDLD
                     DY"
                     /name="ccgAII"
     gene            complement(40177..40356)
                     /gene="ccgAI"
                     /locus_tag="IST04_RS00265"
     CDS             complement(40177..40356)
                     /gene="ccgAI"
                     /locus_tag="IST04_RS00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgAI"
                     /protein_id="WP_000214483.1"
                     /translation="MTTVTTPSQLKKEVESQKELLLRACLEAFNQLPNQRLQGAFTSTY
                     ALAAKLDQLLQQTK"
                     /name="ccgAI"
     gene            complement(41083..41592)
                     /locus_tag="IST04_RS00270"
     CDS             complement(41083..41592)
                     /locus_tag="IST04_RS00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="WP_000129958.1"
                     /translation="MTDITTPSVYVGTYHKYNCGSIAGAWLDLTDFDSSEEFYERCREL
                     HANEADPEFMFQDWEGIPSDMASECHINWDFINGFKQAREEGNEAAFVAFVDLFNSTDF
                     DLFRDAYMGEAKDEETFAEEYLNDSGLLNEIPESVARYFDIVAYARDLFIGDFSLHDGH
                     VFNMTC"
                     /name="antirestriction protein ArdA"
     gene            complement(42945..43277)
                     /locus_tag="IST04_RS00275"
     CDS             complement(42945..43277)
                     /locus_tag="IST04_RS00275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012561126.1"
                     /translation="MDYQTRLNSDITKEIDYLASLRKQRMVADLRTELVYGSLERLADM
                     ICNTVTDWSLPCPVLPLSSVQQWHKAREIVLADYEDFGHDAWDFARHYMKTELSFGYAC
                     YKDDIA"
                     /name="hypothetical protein"
     gene            complement(43486..43770)
                     /gene="ccgC"
                     /locus_tag="IST04_RS00280"
     CDS             complement(43486..43770)
                     /gene="ccgC"
                     /locus_tag="IST04_RS00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgC"
                     /protein_id="WP_001750002.1"
                     /translation="MYHYLVFVPLALIFSAAALALPWFIVRAGYRDLVQITCACVSVLG
                     LCAATGVFSYFDNKPLAFLYGCGALACFLYAVDCAIPLYMTRKKPRKQL"
                     /name="ccgC"
     gene            complement(43839..44198)
                     /locus_tag="IST04_RS00285"
     CDS             complement(43839..44198)
                     /locus_tag="IST04_RS00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019706033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001750003.1"
                     /translation="MSKGNKMLINRIAVIGLAVVAAATQAGVPPVKFFYRDTVPVSITL
                     DEPATGCSMAGVIVHPVDRPAAKVAWFSERICGKKRYPVSFISDEISAPHNVIHKGEKF
                     HVTPAQVNLLDAQNL"
                     /name="hypothetical protein"
     gene            complement(44195..44491)
                     /gene="ccgD"
                     /locus_tag="IST04_RS00290"
     CDS             complement(44195..44491)
                     /gene="ccgD"
                     /locus_tag="IST04_RS00290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000545925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgD"
                     /protein_id="WP_000545925.1"
                     /translation="MHFTNFLQRYFDIEIEHTFDPTIQGSNETGKDVTKIWIYEKGEDS
                     EPLLTLTEAWWYTETKTAGNWLIGNVYSTLEHGREIHESEFRKLVTAGKVISA"
                     /name="ccgD"
     gene            complement(45377..45616)
                     /locus_tag="IST04_RS00295"
     CDS             complement(45377..45616)
                     /locus_tag="IST04_RS00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000932975.1"
                     /translation="MLNKTENNTNISSINPCSTESLIAVTGNDGETHIIQRELISHSVE
                     GHEATIIHLVTGKSIRVSLSSEILAKKLGITVSE"
                     /name="hypothetical protein"
     gene            complement(45626..46030)
                     /gene="ardR"
                     /locus_tag="IST04_RS00300"
     CDS             complement(45626..46030)
                     /gene="ardR"
                     /locus_tag="IST04_RS00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdR"
                     /protein_id="WP_000881513.1"
                     /translation="MLATLQHPTAWQLPDRLMLLELLMFDYRNSDQERYGQQIYHHYRK
                     QGNHRWDTSVHQDSGGQYAIIFRHSFSKKQADGVKRTMIRDETVIRAGTAQELTEATFP
                     DFQDSDILKASDFFKSLIQRKAADVTQTDI"
                     /name="ardR"
     gene            complement(46088..46513)
                     /gene="ardB"
                     /locus_tag="IST04_RS00305"
     CDS             complement(46088..46513)
                     /gene="ardB"
                     /locus_tag="IST04_RS00305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdB"
                     /protein_id="WP_000447669.1"
                     /translation="METIEITARYISENARMNFMPAAFRGAFFSADHFIQSFLNRYAKD
                     YQGGYWEYLQASNGAFFMEAPQPLWLSLPNYFEGECSAREVGIIVCLYAYSYFCGLAYE
                     EGKAELNETMANRYHLLREYVNTLENESQNRIYRAID"
                     /name="ardB"
     gene            complement(47195..48070)
                     /locus_tag="IST04_RS00310"
     CDS             complement(47195..48070)
                     /locus_tag="IST04_RS00310"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class A beta-lactamase CTX-M-2"
                     /protein_id="WP_025368620.1"
                     /translation="MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSG
                     GRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSD
                     LVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETF
                     RLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSA
                     SIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAESRRDILA
                     AAAKIVTHGF"
                     /name="extended-spectrum class A beta-lactamase CTX-M-2"
     gene            complement(48327..49589)
                     /locus_tag="IST04_RS00315"
     CDS             complement(48327..49589)
                     /locus_tag="IST04_RS00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /protein_id="WP_000608644.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDST
                     NKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFKTT
                     QMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQF
                     AFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIET
                     IESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRV
                     LKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGH
                     LLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            <49783..50226
                     /gene="mucB"
                     /locus_tag="IST04_RS00320"
                     /pseudo=""
     CDS             <49783..50226
                     /gene="mucB"
                     /locus_tag="IST04_RS00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     MucB"
                     /name="mucB"
     gene            50377..51168
                     /locus_tag="IST04_RS00325"
     CDS             50377..51168
                     /locus_tag="IST04_RS00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_001452808.1"
                     /translation="MNLPTPETYDELQRAYDFFNEKLFSNELPPCLITLQREKRTYGYC
                     SFKRFVGRESGYTVDEIAMNPVYFSIRTIKATLSTLVHEMVHQWQFHFGEPGRRGYHNK
                     QWAARMERVGLMPSDTGEPGGRKVGQSMTHYIIAGGPFDMACDELLTGHFRLSWMDRFP
                     PYQPKPGAVLSPTGKGYIDDEEDDSEHEQEVEEGRDPVELDDEIIEAMRFVTPPPEAPV
                     NKTNREKYSCPVCHINLWGKPGIVVYCGGEHCNKAALVVLK"
                     /name="SprT-like domain-containing protein"
     gene            complement(51183..51524)
                     /gene="ardK"
                     /locus_tag="IST04_RS00330"
     CDS             complement(51183..51524)
                     /gene="ardK"
                     /locus_tag="IST04_RS00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdK"
                     /protein_id="WP_000057569.1"
                     /translation="MAQKNRISETEWKQLLPQMASFAHITTDIGYSVLVKGEKSSDVAT
                     RVGRSKQNISSTVKRIWDLYQNTTLKAENGEPLKLVQVWIPASLAETVLKEAAKYSINN
                     ITTSEMEKK"
                     /name="ardK"
     ARG             8152..8495
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6324..7060
                     /name="blaIMP-6"
                     /gene="blaIMP-6"
                     /gene_name="subclass B1 metallo-beta-lactamase IMP-6"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(47199..48070)
                     /name="blaCTX-M-2"
                     /gene="blaCTX-M-2"
                     /gene_name="extended-spectrum class A beta-lactamase
                     CTX-M-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7197..7984
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA2"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7209..7987
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             5627..6246
                     /name="AAC(6')-Ib9"
                     /gene="AAC(6')-Ib9"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.57"
                     /coverage="101.48"
     Typing          complement(37223..37489)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="8.36e-138"
     Typing          102..820
                     /name="IncN"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.722"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(32038..35213)
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          18272..18585
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="6.62e-63"
     Typing          18589..21185
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22171..23207
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.422"
                     /coverage="100.0"
                     /evalue="3.38e-180"
     Typing          23430..24124
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1e-154"
     Typing          24139..25019
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.2e-176"
     Typing          complement(35217..36742)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.411"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggaattggcc caccttagac gaaactgtaa aaaatgtatt tacttgtttg aactttgtgg
       61 tagtgtggag agtaattttt aacccacaaa ggcaaggctc atggataagt tgctgaacaa
      121 aaagataaaa gttaagcagt ctaacgagct taccgaagct gcttactacc tctcgctaaa
      181 agcaaagcgc gttctctggt tatgtcttat gcagacgtat ttcacagctt cagtaagcga
      241 agatgatgat gagatggctg tactcggtga ctctactttc aaagtaaagg tggctgacta
      301 tgagcaaatt tttcaggtaa gccgtaacca ggctatcaag gatgttaaag aaggcgtgtt
      361 tgagttaagc cgttctgcgg taatctttta cccgaaagaa gggagttttg actgcgtcgc
      421 gcgcccctgg ctaacagagg ctggcagccg atcagctcgt ggtatctggg aaatcgaatt
      481 taaccataaa ctcctgcggt acatttacgg cctgacgaac cagttcacca cctactcgct
      541 ccgcgattgt ggcagtcttc gaaatccacg gacgatccgc ctttatgaaa gtcttgctca
      601 attcaaatct tcaggcttat gggttactac tcatgcttgg ttaaatgacc gtttcctttt
      661 gccggaatcc caacagaaga acttggcaga gttgaaacga tctttccttg atcctgcact
      721 caagcagata aatgagaaaa cacctttact tgctaagtat agtattgatg attcaggaaa
      781 atttctgttc tcaataattg ataagcaaaa tcccgtctga cataaatcag cacacatgag
      841 cctgtcattt gacaaatttt tgtcatgaag atgggcgaat ttccacacag caccggcgcc
      901 cggcaaggtg ggcggattcc cacacggcac cggcgcccgg caaggtgggc ggattcccac
      961 acggcaccgg cgcccggcaa ggtgggcgga tttccacacg gcaccggcgc ccggcaaggt
     1021 gggcggattc ccacacggca ccggcgcccg gcaaggtggg cggatttcca cacggcaccg
     1081 gcgcccggca aggtgggcgg attcccacac ggcaccggcg cccggcaagg tgggcggatt
     1141 cccacacggc tccggcgccc ggaaagggtg ggcggatttc cacacagcac cggcgcccgg
     1201 caaggtgggc ggattcccac acggcaccgg cgcccggaaa gggtgggcgg atttccacac
     1261 agcaccggcg cccggcaagg tgggcggatt tccacacggc accggcgccc ggcaaggtgg
     1321 gcggattccc acacggcacc ggcgcccggc aaggtgggcg gattcccaca cggctccggc
     1381 gcccggcaag gtgggcggat tcccacacgg caccggcgcc cggcaaggtg ggcggattcc
     1441 cacacggctc cggcgcccgg aaagggtggg cggatttcca cacagcaccg gcgcccggca
     1501 aggtgggcgg attcccacac ggcaccggcg cccggcaagg tgggcggatt cccacacggc
     1561 tccggcgccc ggaaagggtg ggcggatttc cacacagcac cggcgcccgg caaggtgggc
     1621 ggattcccac acggcaccgg cgcccggaaa gggtgggcgg atttccacac agcaccggcg
     1681 cccggcaagg tgggcggatt tccacacggc accggcgccc ggcaaggtgg ggggattccc
     1741 acacggcacc ggcgcccggc aaggtgggcg gattcccaca cggcaccggc gcccggcaag
     1801 gtgggcggat tcccacacgg ctccggcgcc cggcaaggtg ggcggattcc cacacagcac
     1861 cggcgcccgg caaggtgggc ggattcccac acagcaccgg cgcccggcaa ggtgggcgga
     1921 ttcccacacg gcaccggcgc ccggcaaggt gggcggattt ccacacggca ccggcacccg
     1981 gcaaggtggg cggattccca cacggcaccg gcgcccggca aggtgggcgg atttccacac
     2041 agcaccggcg cccggcaagg tgggtggatt cccacacggc accggcgccc ggtaaggtgg
     2101 gcggatttcc acacgacagc ggcgcccggc aagatgggcg gattcccata tcgacatgta
     2161 tgtagcttgt gttatccgtg gattgtgcag ctcagcgggt cgctggtcgt atggcgtagt
     2221 gtcccccgta accggccgcg tgcggccgct aactcgcagt acggcgccgc gacccgaagg
     2281 cgggccgccg ttcccgcgcg caggcgcgcg gcgcccactg cgcacccccg tgggggacat
     2341 acggcagctg tgtggcggtg agcgggatta gggctttgca gggagggggc tgggtcgggc
     2401 gatacgttca gcattgcggt ttccggcgat ttgcggccgg tgcccgttta actccggcgt
     2461 ggtcgccttc catgccctga cggcataaga aaataaaacc gccatgctgc ggtcattcat
     2521 gattttgtgg tgtagcgata aatagtcatg cgagaaacgt tgaagcgctt agcaactgca
     2581 ccaactgtca tttcaggatc agcaagtaag attctaattt gtttaacatc ttcttcagaa
     2641 agtgacggtt ttctccctcc cacacggccc cttgcgcgtg cagctgcaag gcctgagcgc
     2701 gttctttcaa tattgcggtt gcgttcaaag ctagagaata tcgccatcag atgagtatag
     2761 atttccccta taactggcgc atttgtgtct attctgtcct tgatggctat gaaagttatt
     2821 ccgcgtttct tcaggtcgtc gagtaaagta atgacttgac ccaatgaacc gccgagccga
     2881 tctagtgccc aaactactag ggtatctccc tcgcgcaatg ctttcaggca gttctccagt
     2941 tccggcgcac cttttttgtc gcgctttggg ccgctacgtg aggtctgatc ctgatagatt
     3001 tgctcacatc cagcttttgt tagttcgtca acctggtgcg ccacatcctg aagatgcgta
     3061 gatttacgtg catagccgat tttcattctt ttctcgctaa ttagttatgg ggttattgtt
     3121 atgttgatac agtaacgagt tttgttacat gaggggagtc atttttcggg agaagtcagg
     3181 acttttcaag actgtcacaa aaaccatcgt ttttgataca ttaatttaac caataggttg
     3241 cagatcaaat cgcctgtaac agcctttctg gctgtttgtc gttttcagaa gacggctgca
     3301 ctgaacgtca gaagccgact gcactatagc agcggagggg ttggatccat caggcaacga
     3361 cgggctgctg ccggccatca gcggacgcag ggaggacttt ccgcaaccgg ccgttcgatg
     3421 cggcaccgat ggccttcgcg caggggtagt gaatccgcca ggattgactt gcgctgccct
     3481 acctctcact agtgaggggc ggcagcgcat caagcggtga gcgcactccg gcaccgccaa
     3541 ctttcagcac atgcgtgtaa atcatcgtcg tagagacgtc ggaatggccg agcagatcct
     3601 gcacggttcg aatgtcgtaa ccgctgcgga gcaaggccgt cgcgaacgag tggcggaggg
     3661 tgtgcggtgt ggcgggcttc gtgatgcctg cttgttctac ggcacgtttg aaggcgcgct
     3721 gaaaggtctg gtcatacatg tgatggcgac gcacgacacc gctccgtgga tcggtcgaat
     3781 gcgtgtgctg cgcaaaaacc cagaaccacg gccaggaatg cccggcgcgc ggatacttcc
     3841 gctcaagggc gtcgggaagc gcaacgccgc tgcggccctc ggcctggtcc ttcagccacc
     3901 atgcccgtgc acgcgacagc tgctcgcgca ggctgggtgc caagctctcg ggtaacatca
     3961 aggcccgatc cttggagccc ttgccctccc gcacgatgat cgtgccgtga tcgaaatcca
     4021 gatccttgac ccgcagttgc aaaccctcac tgatccgcat gcccgttcca tacagaagct
     4081 gggcgaacaa acgatgctcg ccttccagaa aaccgaggat gcgaaccact tcatccgggg
     4141 tcagcaccac cggcaagcgc cgcgacggcc gaggtcttcc gatctcctga agccagggca
     4201 gatccgtggg cactgttgca aagttagcga tgaggcagcg ttttgtctta ttcaaaggcc
     4261 ttacatttca aaaactctgc ttaccaggcg catttcgccc aggggatcac cataataaaa
     4321 tgctgaggcc tggcctttgc gtagtgcacg catcacctca atacctttga tggtggcgta
     4381 agccgtcttc atggatttaa atcccagcgt ggcgccgatt atccgtttca gtttgccatg
     4441 atcgcattca atcacgttgt tccggtactt aatctgtcgg tgttcaacgt cagacgggca
     4501 ccggccttcg cgtttgagca gagcaagcgc gcgaccatag gcgggcgctt tatccgtgtt
     4561 gatgaatcgc gggatctgcc acttcttcac gttgttgagg attttaccca gaaaccggta
     4621 tgcagctttg ctgttacgac gggaggagag ataaaaatcg acagtgcggc cccggctgtc
     4681 gacggcccgg tacagatacg cccagcggcc attgaccttc acgtaggttt catccatgtg
     4741 ccacgggcaa agatcggaag ggttacgcca gtaccagcgc agccgttttt ccatttcagg
     4801 cgcataacgc tgaacccagc ggtaaatcgt ggagtgatcg acattcactc cgcgttcagc
     4861 cagcatctcc tgcagctcac ggtaactgat gccgtatttg cagtaccagc gtacggccca
     4921 cagaatgatg tcacgctgaa aatgccggcc tttgaatggg ttcatgtgca gctccatcag
     4981 caaaagggga tgataagttt atcaccaccg actatttgca acagtgccaa tcgtggagtg
     5041 atcgacattc actccgcgtt cagccagcat ctcctgcagc tcacggtaac tgatgccgta
     5101 tttgcagtac cagcgtacgg cccacagaat gatgtcacgc tgaaaatgcc ggcctttgaa
     5161 tgggttcatg tgcagctcca tcagcaaaag gggatgataa gtttatcacc accgactatt
     5221 tgcaacagtg ccgatccgtg cacagcacct tgccgtagaa gaacagcaag gccgccaatg
     5281 cctgacgatg cgtggagacc gaaaccttgc gctcgttcgc cagccaggac agaaatgcct
     5341 cgacttcgct gctgcccaag gttgccgggt gacgcacacc gtggaaacgg atgaaggcac
     5401 gaacccagtg gacataagcc tgttcggttc gtaaactgta atgcaagtag cgtatgcgct
     5461 cacgcaactg gtccagaacc ttgaccgaac gcagcggtgg taacggcgca gtggcggttt
     5521 tcatggcttg ttatgactgt ttttttgtac agtctatgcc tcgggcatcc aagcagcaag
     5581 cgcgttacgc cgtgggtcga tgtttgatgt tatggagcag caacgatgtt acgcagcagg
     5641 cagcagggca gtcgccctaa aacaaagtta ggcatcacaa agtacagcat cgtgaccaac
     5701 agcaccgatt ccgtcacact gcgcctcatg actgagcatg accttgcgat gctctatgag
     5761 tggctaaatc gatctcatat cgtcgagtgg tggggcggag aagaagcacg cccgacactt
     5821 gctgacgtac aggaacagta cttgccaagc gttttagcgc aagagtccgt cactccatac
     5881 attgcaatgc tgaatggaga gccgattggg tatgcccagt cgtacgttgc tcttggaagc
     5941 ggggacggat ggtgggaaga agaaaccgat ccaggagtac gcggaataga ccagtcactg
     6001 gcgaatgcat cacaactggg caaaggcttg ggaaccaagc tggttcgagc tctggttgag
     6061 ttgctgttca atgatcccga ggtcaccaag atccaaacgg acccgtcgcc gagcaacttg
     6121 cgagcgatcc gatgctacga gaaagcgggg tttgagaggc aaggtaccgt aaccacccca
     6181 gatggtccag ccgtgtacat ggttcaaaca cgccaggcat tcgagcgaac acgcagtgat
     6241 gcctaaccct tccatcgagg gggacgtcca agggctggcg cccttggccg cccctcatgt
     6301 caaacgttag aaaaggaaaa gtatgagcaa gttatctgta ttctttatat ttttgttttg
     6361 cagcattgct accgcagcag agtctttgcc agatttaaaa attgaaaagc ttgatgaagg
     6421 cgtttatgtt catacttcgt ttgaagaagt taacgggtgg ggcgttgttc ctaaacatgg
     6481 tttggtggtt cttgtaaatg ctgaggctta cctaattgac actccattta cggctaaaga
     6541 tactgaaaag ttagtcactt ggtttgtgga gcgtggctat aaaataaaag gcagcatttc
     6601 ctctcatttt catagcgaca gcacgggcgg aatagagtgg cttaattctc gatctatccc
     6661 cacgtatgca tctgaattaa caaatgaact gcttaaaaaa gacggtaagg ttcaagccac
     6721 aaattcattt agcggagtta actattggct agttaaaaat aaaattgaag ttttttatcc
     6781 aggcccggga cacactccag ataacgtagt ggtttggttg cctgaaagga aaatattatt
     6841 cggtggttgt tttattaaac cgtacggttt aggcaatttg ggtgacgcaa atatagaagc
     6901 ttggccaaag tccgccaaat tattaaagtc caaatatggt aaggcaaaac tggttgttcc
     6961 aggtcacagt gaagttggag acgcatcact cttgaaactt acattagagc aggcggttaa
     7021 agggttaaac gaaagtaaaa aaccatcaaa accaagcaac taaatttcta acaagtcgtt
     7081 gcagcacgcc actacgtggc tggacagttt gtaagttgcg cttttgtggt ttgcttcgca
     7141 aagtattcca caacgcgcaa cttacaaact gccgctgaac ttagcgttag acatcatgag
     7201 ggtagcggtg accatcgaaa tttcgaacca actatcagag gtgctaagcg tcattgagcg
     7261 ccatctggaa tcaacgttgc tggccgtgca tttgtacggc tccgcagtgg atggcggcct
     7321 gaagccatac agcgatattg atttgttggt tactgtggcc gtaaagcttg atgaaacgac
     7381 gcggcgagca ttgctcaatg accttatgga ggcttcggct ttccctggcg agagcgagac
     7441 gctccgcgct atagaagtca cccttgtcgt gcatgacgac atcatcccgt ggcgttatcc
     7501 ggctaagcgc gagctgcaat ttggagaatg gcagcgcaat gacattcttg cgggtatctt
     7561 cgagccagcc atgatcgaca ttgatctagc tatcctgctt acaaaagcaa gagaacatag
     7621 cgttgccttg gtaggtccgg cagcggagga attctttgac ccggttcctg aacaggatct
     7681 attcgaggcg ctgagggaaa ccttgaagct atggaactcg cagcccgact gggccggcga
     7741 tgagcgaaat gtagtgctta cgttgtcccg catttggtac agcgcaataa ccggcaaaat
     7801 cgcgccgaag gatgtcgctg ccgactgggc aataaaacgc ctacctgccc agtatcagcc
     7861 cgtcttactt gaagctaagc aagcttatct gggacaaaaa gaagatcact tggcctcacg
     7921 cgcagatcac ttggaagaat ttattcgctt tgtgaaaggc gagatcatca agtcagttgg
     7981 taaatgatgt ctaacaattc gttcaagccg accgcgctac gcgcggcggc ttaactccgg
     8041 cgttagatgc actaagcaca taattgctca cagccaaact atcaggtcaa gtctgctttt
     8101 attattttta agcgtgcata ataagcccta cacaaattgg gagatatatc atgaaaggct
     8161 ggctttttct tgttatcgca atagttggcg aagtaatcgc aacatccgca ttaaaatcta
     8221 gcgagggctt tactaagctt gccccttccg ccgttgtcat aatcggttat ggcatcgcat
     8281 tttattttct ttctctggtt ctgaaatcca tccctgtcgg tgttgcttat gcagtctggt
     8341 cgggactcgg cgtcgtcata attacagcca ttgcctggtt gcttcatggg caaaagcttg
     8401 atgcgtgggg ctttgtaggt atggggctca taattgctgc ctttttgctc gcccgatccc
     8461 catcgtggaa gtcgctgcgg aggccgacgc catggtgacg gtgttcggca ttctgaatct
     8521 caccgaggac tccttcttcg atgagagccg gcggctagac cccgccggcg ctgtcaccgc
     8581 ggcgatcgaa atgctgcgag tcggatcaga cgtcgtggat gtcggaccgg ccgccagcca
     8641 tccggacgcg aggcctgtat cgccggccga tgagatcaga cgtattgcgc cgctcttaga
     8701 cgccctgtcc gatcagatgc accgtgtttc aatcgacagc ttccaaccgg aaacccagcg
     8761 ctatgcgctc aagcgcggcg tgggctacct gaacgatatc caaggatttc ctgaccctgc
     8821 gctctatccc gatattgctg aggcggactg caggctggtg gttatgcact cagcgcagcg
     8881 ggatggcatc gccacccgca ccggtcacct tcgacccgaa gacgcgctcg acgagattgt
     8941 gcggttcttc gaggcgcggg tttccgcctt gcgacggagc ggggtcgctg ccgaccggct
     9001 catcctcgat ccggggatgg gatttttctt gagccccgca ccggaaacat cgctgcacgt
     9061 gctgtcgaac cttcaaaagc tgaagtcggc gttggggctt ccgctattgg tctcggtgtc
     9121 gcggaaatcc ttcttgggcg ccaccgttgg ccttcctgta aaggatctgg gtccagcgag
     9181 ccttgcggcg gaacttcacg cgatcggcaa tggcgctgac tacgtccgca cccacgcgcc
     9241 tggagatctg cgaagcgcaa tcaccttctc ggaaaccctc gcgaaatttc gcagtcgcga
     9301 cgccagagac cgagggttag atcatgccta gcattcacct tccggccgcc cgctagcgga
     9361 ccctggtcag gttccgcgaa ggtgggcgca gacatgctgg gctcgtcagg atcaaactgc
     9421 actatgaggc ggcggttcat accgcgccag gggagcgaat ggacagcgag gagcctccga
     9481 acgttcgggt cgcctgctcg ggtgatatcg acgaggttgt gcggctgatg cacgacgctg
     9541 cggcgtggat gtccgccaag ggaacgcccg cctgggacgt cgcgcggatc gaccggacat
     9601 tcgcggagac cttcgtcctg agatccgagc tcctagtcgc gagttgcagc gacggcatcg
     9661 tcggctgttg caccttgtcg gccgaggatc ccgagttctg gcccgacgcc ctcaaggggg
     9721 aggccgcata tctgcacaag ctcgcggtgc gacggacaca tgcgggccgg ggtgtcagct
     9781 ccgcgctgat cgaggcttgc cgccatgccg cgcgaacgca ggggtgcgcc aagctgcggc
     9841 tcgactgcca cccgaacctg cgtggcctat acgagcggct cggattcacc cacgtcgaca
     9901 ctttcaatcc cggctgggat ccaaccttca tcgcagaacg cctagaactc gaaatctaac
     9961 gtccgttcgg gcatcgaggt ccatgtcggg gtgggacggg cccgtggctt caagatcact
    10021 tgcagtccga ccgcgatgtc ttggttgcgc gagaggttgt cgatatcctc cacttccatc
    10081 atcaaccctg gataatgccg ccgccgtcat cgccgccgac gcccgtgccg ggcttttcgg
    10141 gcctgtcagg cttgctcggc cttcagcctg cctgggcgag atctccggcg gacggattaa
    10201 cggcggagct tcgccgcctt tcgtgcgtgt gaaggccgaa gatagttctc tcaaaaacat
    10261 ccgtttatga gagataccaa atgtcatttt cagaagacga ctgcaccagt tgattgggcg
    10321 taatggctgt tgtgcagcca gctcctgaca gttcaatatc agaagtgatc tgcaccaatc
    10381 tcgactatgc tcaatactcg tgtgggctct gttgcaaaaa tcgtgaagct tgagcatgct
    10441 tggcggagat tggacggacg gaacgatgac ggatttcaag tggcgccatt tccagggtga
    10501 tgtgatcctg tgggcggtgc gctggtattg tcgctatccg atcagctatc gcgaccttga
    10561 ggaaatgctg gcggaacgcg gcatttcggt cgaccatacg acgatctatc gctgggtcca
    10621 gtgctacgcc ccggagatgg agaagcggct gcgctggttc tggcggcgtg gctttgatcc
    10681 gagctggcgc ctggatgaaa cctacgtcaa ggtgcggggc aagtggacct acctgtaccg
    10741 ggcagtcgac aagcggggcg acacgatcga tttctacctg tcgccgaccc gcagcgccaa
    10801 ggcagcgaag cggttcctgg gcaaggccct gcgaggcctg aagcactggg aaaagcctgc
    10861 cacgctcaat accgacaaag cgccgagcta tggtgcagcg atcaccgaat tgaagcgcga
    10921 aggaaagctg gaccgggaga cggcccaccg gcaggtgaag tatctcaata acgtgatcga
    10981 ggccgatcac ggaaagctca agatactgat caagccggtg cgcggtttca aatcgatccc
    11041 cacggcctat gccacgatca agggattcga agtcatgcga gccctgcgca aaggacaggc
    11101 tcgcccctgg tgcctgcagc ccggcatcag gggcgaggtg cgccttgtgg agagagcttt
    11161 tggcattggg ccctcggcgc tgacggaggc catgggcatg ctcaaccacc atttcgcagc
    11221 agccgcctga tcggcgcaga gcgacagcct acctctgact gccgccaatc tttgcaacag
    11281 agcctccgtc gccatgctca cctcgctttg gtgcacacga gtattgagca tagtcgagat
    11341 tggtgcagat cacttctgat attgaactgt caggagctgg ctgcacaaca gccattacgc
    11401 ccaatcaact ggtgcagtcg tcttctgaaa atgacactgt ttgtatataa tcatgaaaaa
    11461 atggtgagta gagtttcagg gtaacagggg atgcttatgt cggttttcca caactggcta
    11521 cttgagatcg catgtgagaa ttacttcgtc tacatcaaac gcctttccgc caacgatacc
    11581 ggcgcaacag gtggtcacca ggtagggctt tatatccctt caggtatcgt tgaaaaactc
    11641 tttccgtcta tcaaccatac ccgtgaactg aacccttcgg tttttctcac cgcacatgtg
    11701 tcatcgcatg attgccctga cagcgaagcc agggcaattt attataacag ccgtcatttt
    11761 ggtaaaaccc ggaatgaaaa aaggattacc cgctggggta gaggcagccc acttcaggat
    11821 cctgaaaata caggggctct gacgctcctg gctttcaagc ttgatgagca agggggggac
    11881 tgtaaggaag taaatatttg ggtatgcgcc agcactgatg aagaggacgt cattgagacc
    11941 gctattggtg aagttatacc cggagcgctt atatccggcc ccgcaggaca gattctaggc
    12001 ggactatctc tacagcaagc gccagtaaat cataaatata ttctacctga agactggcac
    12061 ctgcgctttc cgtcgggaag tgaaattatt cagtatgcag ccagccatta tgtgaaaaat
    12121 tcccttgatc cggatgagca acttcttgac cgccggcgcg tggagtacga catatttcta
    12181 ttggttgagg aactgcatgt tctggatatc atccggaaag gatttggctc tgtggatgaa
    12241 tttattgcgc tggccaattc tgtcagcaat cgccgtaaat ccagagccgg gaagtcgctg
    12301 gaactgcacc tggagcatct attcattgag cacggcctgc gacactttgc gacgcaggcc
    12361 atcacagaag gtaataaaaa acccgatttc cttttccctt ccgcaggggc ttaccacgat
    12421 actgagtttc ccgtagaaaa tctgcgcatg ctggcagtca agactacctg taaggatcgc
    12481 tggcgtcaga tactgaatga ggccgataaa attcatcagg tgcatctgtt tacactccag
    12541 gagggagttt ctctggctca atatcgggag atgcgggagt cgggtgtcag attggtcgtg
    12601 ccatcatctc tgcacaaaaa atacccggag gcggtgagag ctgagctaat gacgctaggt
    12661 gcgtttattg ctgagctgac agggctttac gcagatattc catagattat ctcccggcat
    12721 aaataccggg aggagcgatc agattcgttc aaccttgcac gaatcggcat taaccgcttt
    12781 caggatataa ggttcaagca gtttggctac ggcttcaaac acgggcacca ctacggagtt
    12841 accgaactgc ctgtacgact gagtgtctga cacaggaatg cgaaaaggcc tgccatctac
    12901 tttttcaaaa cccataaggc gcgcgcactc tcgcggagtc agcctgcggg gccgatgcgc
    12961 ctgattttct tcgttcgcga agtctgtttc acctgtggcc atatcccagc cacggtctat
    13021 cagaatttca gacccgtctt tgtgatagcg agcagaaagc gtacgggcaa tgctttcttt
    13081 attttcagga ttaacgaggc caaaaccgaa tccgttaccc ttagctgcgt gctttttggc
    13141 gtagttatag agatactccc agagtttcgg cgtcagtata tatttgctgt caaccacggg
    13201 ttccagcagt tcgccaaatg acggacgctg ttccggataa aaacgactaa tatcgcgcag
    13261 ggtaaagccc tggtgaatgt tcagatcacg gcggaaaccg accaaaacga tacgttctcg
    13321 gtgctgaggt aaaaagtgct ttccgtcgat aactttagga tcgtttttgc ccatctcagc
    13381 tgcatccgca acttcatagc ccagttcgtc gagggtatcc atgatgactt taaaggtttt
    13441 acccttgtca tggctcttca ggtttttaac gttttcaaga acaaagatgg caggtttttt
    13501 tgcgcggata atacgcgcca catcgaagaa aagcgttccc tgagcctcac attcgaaacc
    13561 atgcgcgcgc ccgagcgagt ttttcttgct tacgcccgca aggctaaacg gttgacaggg
    13621 gaaacctgct agaagtacat catgatccgg cacatgctca ttaatgtaag cataggcatc
    13681 gttttcaggt acttcaggtt tatcactgag cgtgacttca cgaatatcga gattgaaagt
    13741 gtgttcctga gcatcgttaa accagttagc tttatatgtg cgcacagcct ctttattcca
    13801 ttcactggta aaaacgcact ggccaccgat ggtttcgaag cccttccgta tacctccaat
    13861 cccagcaaac aggtcaataa accggaaggc atagtcaggg tgatgtgcag gcgcttccgg
    13921 aagcattttt cgtagaagtt cctcttcggc taacgtcagc gtcttaggtg agcacttacc
    13981 attaatccag cgattaagag tctcgcgact ccactcattt ttaccaactt ttctaagcag
    14041 ttcagccacg tacttctggt catagatttc cagcacctgc ccgagcagct ttttatcatt
    14101 ttcctgtcgc agttgttctt ccgcttctgc tttctcaagc agatcctgcg ccagtaattc
    14161 aaattcagac atattgcctc cattgggtct tatgggtgaa actgtatcac tcatttgacc
    14221 cagattgaat gtttttatct ggatatttaa acaggtttat tgttaggtaa cgcacgttgg
    14281 ccacgctgga gcgtcttctg ggcctgctgt cggcctttga ggtcgtggta tggatgacgg
    14341 atggctggcc gctgtatgaa ccccgcctga agggaaagct gcacgttatc agcaagcgtt
    14401 acactcagcg cattgagcga cataacctga atctgagaca acatctggca aggctgggac
    14461 ggaagtcact gtcgttctca aaatcggtgg agctgcatga caaggtcatc gggcattatc
    14521 tgaacataaa acactatcag taagttggag tcattaccgg ttctctttgt cttttagtga
    14581 ttctataaac ctcattacgt ctgaatataa aaatctatta tttgatttat gtggctcatg
    14641 aggttgtggg atggtcttgt ttttgaatgt gccagttttc ttaatggcaa agattaactc
    14701 accttctgtt attcctaaca tttcagcaaa tgtttttgct tctatagtta ctgacttcat
    14761 ttaattaact ctcatggtat cgattttctt taccggcatc tttaacaatg gtgctcgttt
    14821 ctagtgttgc tgcggtacgc ttcatcatcg tctgcggggc ggttgcgata gtgaaggagc
    14881 tgccgggcgt gagcaaatct atcaggcgct ggccgctgat aatctccatc cgttcactgg
    14941 caatactgac agattttgaa cctgcgccgg ttttcccggt atggcaaaac agaccgcgac
    15001 agttatgacg tttaagcaac ttctcgaact cctgtacgtg ctgtaaagca atatggccgc
    15061 gatagcgttt agcctgaata agatagcgat attttcctat tattacctgg ccgtcaatgc
    15121 ctccatcgcc ggtatagcgt ttgtttctga tggttctgaa gccatgcgct tcaaatcctt
    15181 ccagcaacag ttcttcaaac acaaaaggat caattttcct caggtagtta attttttgtg
    15241 ggaagcccgg caacgtcttt atgcgctcca gcacccgccg cgcactttgc tgcttccttt
    15301 tgtgtcgcct gtgccgtact gaacgccgga agaatacaac ggcaagcagt gcgatggcgc
    15361 tgcaagccca tagaataagg ttttctgtag tggggaaggg gatcatggtc atagtgggct
    15421 ttctgagggt aaagaaaagg gcggttaaac cgccctggtg tttagcgacg gctgtatacc
    15481 tgccacgaag cgctgcctga ctgattctgg caaatccgcc cgtaaagtac ggtgccggtc
    15541 gagtagcggg cgccattcag atagcaatag ccgctggatt gcagcagttc gttgcgcagc
    15601 ttttcttcct gctttgatag ccgggactcc gcagactgca aacgaacgga taattcgtta
    15661 atctggcgtt gctggttatt cagctggctc tgcatcgcat tacctttatc ctggctgacg
    15721 caaccagtta agagagctgt acaggctaat gcacttaata ttattttttt cacgttggct
    15781 ccttaaattg agattattcc tagttcgcct ataagcgaac tttcccgtat ttacttatga
    15841 tctggcttat catcgactgg ttacttccac cttcgccatt atccgggcat tcattaagaa
    15901 aagccttcct ggcatccttc gtgtggttgg gtaaaaagcc gtgcttgttc tttttaacga
    15961 tattgaagaa agcagcttca gcactgttac actcgcttcc gccgctatcg ccggtgagct
    16021 tgcccgccat gcacataata actttgcagg gatcttcagc atggctggca ggaatataaa
    16081 gcagactacc agctgctatc agaggtatta agagtttctt cattgttttg tccttaacag
    16141 tttgttcaga tatacactcg ccagaatgtt gataacggta agcaatatta ataataacgc
    16201 tgcgttataa atagatttgt aacctatatc gcctgcaata tattcgacaa caaaaacgaa
    16261 aatcgttaaa attgtgtaaa acttgattaa ctttcctgta attttcttaa caatataagc
    16321 aactgaataa gagccggatt tgatgatgct ggcgagtaac ctgatcgcat ggacacgaaa
    16381 ttttctaaaa atgggcggaa tggaagatgc ctttttcttc cttctgcttt tttgcctttc
    16441 cgcaaaatca ataagttcgc ccatttttat accctccggt tatatcttca gatcatcaag
    16501 tgataaacca ctatcaagca gctctttgag ccatgtgggt cggcggccag tcccggacca
    16561 ggtattttct gcgttcctgg ggtcgcggta ttttgctggt ctatgttctc tggggttggc
    16621 tacgccctgc atcttcatgg cttccaggct aatgccagcg tccaattttg cagttagcca
    16681 ggccgggcgc ttccctatac cagtccacgt attaaaaggg ttatccgggt cacgatacac
    16741 gggttcgcct tttggtcgtt tttctgattt caggggaacc agcatcacct tccttccttc
    16801 agcggttttc ttttcgtttc ttcttgacac gatctcatta gcccttatca taaacaaaag
    16861 tcgtcgaaat tacaattacg cggtgaaaca taaatgagta aacatccaaa actcctggtt
    16921 ctcgctctgg cctgccttgc ttgtgctggc cgtgccagtg ctgcgcctgc ctccgatgaa
    16981 gttgccaggc ttgcgcagag atgtgcgcct gatgtttcac ccttaacgat ggcgtacatc
    17041 gtcggccatg agtcctcaaa tgggccgtac aggatcaata ttaacggtag tattcagtta
    17101 aaacagcaac cgcgtactga agctgaggcc gtcagcgttg cgaaagttct gctgaaggat
    17161 aataaaagtt ttgatatggg ccttgcacaa attaactcaa ataatttagt gggcctgggt
    17221 ctttcggttg acgatatttt caaaccctgc atcaacctgc gggcgagcca gaccatcctt
    17281 aaagcctgtt atgatagcgc cctgaaatcc tacccagccg ggcaggttgc gctgagacac
    17341 gcgctttcct gctacaacac cggctcactc acaaacggga tttctaacgg gtatgtcacg
    17401 aaagttatca acgtggcgcg tcaatcaact gatttgaaaa tccctacgct gctacctgac
    17461 ggccagacca gtgaggacag caccgcgact gagcctcagc aggcaaaaag tacggcgccg
    17521 cagtatgacg gtgaacaaga tgtttttggt tcgggtgatg gcgatgcctt cagccgaaat
    17581 aatacggatg cctttttaac cagacaggaa acagcgaagg gggaatgagg ttatggatgg
    17641 aacgtttgta ccttgtattg caatcacaga tcctggagct atttgaagca ggaaaagtga
    17701 aggaggtaac gatagaacgg gtttcattaa agaagtggta tcccgttttt cagatagacg
    17761 atgaacagct gggccagatc gcatgttcca ttagggttaa caaagagcat gagctacgaa
    17821 cctgggctga tttaaggcta ctggcagagt ttttgaaaga taagtgtggc gttgaagaat
    17881 gccggttaaa tctgcaatca acagaagata gtgagtaagg agaaagtatg accacgttgt
    17941 ttaagaagta tggccctgcg gtagttatgg gcgttttgtc cattgccctg ccgcaaattg
    18001 cgctggccgc tggcaccgat actggtgaat caaccgctac atcaatccag acgtggttga
    18061 gcacatggat tccaattggt tgtgctattg cgatcatggt tagttgcttt atgtggatgc
    18121 ttcacgtaat cccagccagc tttattcctc gtatcgtaat ctcgctgatt ggtattggtt
    18181 ctgcatcatt tctggtttcc ctgacgggcg taggaagctg aacaacgcga aaagggggga
    18241 cttttgtccc ccaaagtgag gactacaaag atgttcgttg acgggaaaag accgcttttc
    18301 aaaggtgcga ctcgcttacc tcgcgcgctg ggtgtaccac gtaatgtagc tatgatgata
    18361 ttcatgattt ctgcctcgct ttttatgatt attcatatgt gggcgattct ggtgttcgtc
    18421 tttttgtgga ttccttcagc tgcattaaca aaatatgacg accgcatgtt tcgaattatg
    18481 ggcctgtggt tgaaaaccaa attcagtaat tggtttgatt ctccgtttaa gcagtgggga
    18541 ggatcgtctt attcctctgt tgactacaaa cgtaagggtt taaaataatg agagctgcca
    18601 ccgctacgaa gccaaaaaaa attgatgcct accgtaagga gccatcagta aataaaaagt
    18661 atttgcccta ttcttatcac ctcaatgatt acgtgatttc gatggaaaac ggcgatctga
    18721 tggctttttt caagctggat ggccgcacac atgactgcgc atcagatcgg gaactggtca
    18781 cctggcataa agaccttaat acgctggtca agagcttcgg aacagaccat gtagagctgt
    18841 ggacgcatga atatcaccat gaggctaaag agtacccgga tggtgagtat gaccattttt
    18901 tccctgctta tgttgatcaa tataaccgta agctgcacgg tgattccaag cagctgatta
    18961 atgaccttta tctgaccgtt atttacaaac aggtagggga taaaacacag aagtttctgg
    19021 cgaaatttga aaagccgact cgtgacgaaa ttcagcaaat gcagaatgag gcgcttgaag
    19081 gtctggaaga tatttctgaa caaatcctgg aagcaatgaa gccgtatggc attcagcagt
    19141 tgggtatcta ttatcgtgac aaacgcggtg ttgaaattcc tgcgcctgat aaaaaagaac
    19201 gtgaagaact tgctgaagtc gatgaatcag acatttttga cgaagccatt gttatcgaac
    19261 gcaacgagcc tgaaccttcg caggctcacg cttattcaaa agcgctggag ttcctttatt
    19321 tcctcgcaaa tatggaatgg gccatcgtgc ctgtttgccg tgatcgtatc cgtgagtaca
    19381 tcatggacaa ccgccctgtt agctccctgt ggggggatgt tgtccagatc agaacggtag
    19441 atcacaactt ctataccacc ggcattgaat ttcgtgaata cgaagaagat acagagccag
    19501 gccagcttaa catgcttaaa gaagccgatt ttgaatacct tctgacgcag agtttttctt
    19561 gcctctctga atcttcagct aaaacgtttc tgacgcatca ggaaaaatct ttgcaggaaa
    19621 cgcgcgaccg tgcgcaaagc cagctggcac agcttggtac tgcgctcgat atgctgacgt
    19681 ccagagagtt cgtgatgggc taccatcatg gaaccgtgca tgtctgggat aatgaccaaa
    19741 acgcggtaca gcgcaaagcg cgtcgtgtga aggttatgct aaccggctgt ggcgtggttg
    19801 gcgggactat cagcctggcc tctgaggctg catattatgc gagactgcct ggcaaccaga
    19861 aatgggcgcc gcgcccggtt ccgataaact catggaactt cctgcacttc agcccgttcc
    19921 acaattttat gcgtggcaag cctgacaata acccgtgggg gccagcgctg accatgttcc
    19981 gcacgatcag cggtacgcca ctctatttta atttccatgt gaccccgctt gaagaacttt
    20041 cctacggtaa acgcccgctg ggccatgcgt taataacggg tatgtcgggg gaaggtaaaa
    20101 ccacgctgct taacttcctg ctggcgcagt caatgaagta caacccgcgg ctttttgttt
    20161 atgaccgtga ccgcggtatg gagccgttca ttcgaagcgt tggtggctac tataaagttc
    20221 tgcaacaggg tatgccgtcc gggtttgccc cgcttcagat tgaaccgacc aaacgcaata
    20281 ttgccctcat taaaaacctg ttccgcattt gtgtggaaac caccaataac gggcctatca
    20341 gcgcaacgat ggctaccgaa ctggctgaag gcgttgatgc ggttatgggg gaaggctcac
    20401 ttattccacg cgaggcgcgc accgttacta tcctggacgg gtacgtgaat gaagttgtgg
    20461 aaaatggcgt atcactgaaa gggctgctgc gcgaatggac gcgcgaaggc cagtatggct
    20521 ggctgtttga caatgataaa gacagcctgg atctcagcgc gaatgatatt tttggcttcg
    20581 atttatccga gtttatcgca gccaaagagg aagtatccag cccggcccgt actccgctca
    20641 tgatgtacct tctgtaccgg gtacgtgact ccatcgacgg caaacgccgc gtcattcagt
    20701 gctttgacga gttccacgcc taccttgacg atccggttat cgagcgtgaa gttaagcgtg
    20761 gtatcaaaac tgaccgtaag aaagacgcta tctatgtgtt tgccacgcag gagccgaacg
    20821 atgcgctgtc cagccgtatt ggccgcacga tcatgtcgca gaccgtcaca aaaatctgcc
    20881 tgcgcgatcc ggaagctatc cgagaggatt atgccttcct tactgatgct gaatacgacg
    20941 cgctgatgtc gattaccgaa cactccagac agttcctggt taaacaaggg caacagtctg
    21001 cgattgcttc tttcaatctc taccctcgca acagcgacga tattgatgca gatattaaga
    21061 caatggacaa cgttcttagc gtgttgtccg gtgaaccaca aaacgccgaa attgcgcatg
    21121 agctggttga acggctcggt aatgaccctg aagtatggct caaagaatac tggcgcctga
    21181 cggcttaaca acgaggcaaa acaccatgaa aaaaacactg acggcagtat tgctgaccac
    21241 cggcctgatt ctgggaggcg cgcaaagcgc ttccgcaggc atcatcgtga ccaaccctac
    21301 tgagctggct aaacaggtcg agcagcttca gcaaatggcg cagcagctgg agcagcttaa
    21361 aagccagctg caaacgcaga aaaatatgta tgagtcgatg gcaaagacaa ccaacctggg
    21421 cgatctgctg gggacgtcta ccagcacgct ggcaaataat ttgccggaca actggaagga
    21481 gatctacagc gacgccatga actccagttc ttccgtcacg ccttcagtta acagcatgat
    21541 gggccagttt aatgcggaag ttgacgacat gacgcccagc gaagcaatta cctacatgaa
    21601 caaaaagctg gctgaaaaag gcgcttatga ccgcgttatg gcagaaaaag cctacaacaa
    21661 ccagatgcag gaactaaccg atatgcagga gctgacggag cagattaaaa cgactccaga
    21721 cctgaaatcg attgctgact tacaggcccg tatccagacg tcacagggtg ctattcaggg
    21781 tgagcaggcg aagctgaatc tgatgaacat gttgcagcag tcacaggaca agctattacg
    21841 tgcgcagaaa gaacgtgcca cccacaattt tgtttttgga accggcgggg acgttaccgc
    21901 gtcaccttca attaactgag gtaattatga aaaaactact gcttgttatc cctttcctcc
    21961 tggtggcctg cgatgcctcg catgacgtgg agtggtacaa aaaacatgag aaagagcgca
    22021 aggcaacaat tcaggaatgc aagaaagacg cggatgaact tcagaaacct gattgcaaaa
    22081 acgcgcgcga agccgatcgt cagctgtttg tgttcggcaa aaaagacggc gaaatcaatt
    22141 caccgaaaat ttaggagtaa ggaggcaata tggcattcac cctagtcgca gacattttcg
    22201 caaaagtaga cggggcgatt acgtcaatgg tgagcgccaa tgttgccacc attatctctg
    22261 atgtaacgcc tctgattgcc acctgtctga caatcaagct gatggttcag gggatgtact
    22321 cagcgtttaa tccgggggcg ggcgacagcc tgagttcgct gattaaagag tatctttcca
    22381 tagcccttat cctgagcttt gcaacggcgg gcggctggta tcaacaggaa ctggtcaacg
    22441 tggcgcttca cctgccggat gattttgccg ggatactgtc tgcccctaat aaagtcggtg
    22501 caagtggcgt accggcgatt attgatagcg gtattgaaaa aggtatcaag atcgtcaaca
    22561 ccgcatggga agccgcagac gtgttttcat cgagcggcct ggccgcgtat gccattggcg
    22621 gcattatgat gattgctacc gttgtgctgg gcggcctcgg tgcgggcttt gtgatcatgg
    22681 ctaagatcct tctggccgtt acgctttgtt ttggcccgat tgcaatcttc tgcctgctgt
    22741 ggggagcgac aaaaaacatc tttgctcgct ggctggcgtc ggtcattaac tatggccttg
    22801 tcgtcgtcat tcttgcgctc gtgtttggtt tcatcatgca gatgttcgac aacctcctgt
    22861 cctcgatgaa ctctgatgcc gcttactcat caatcactgg ttctatctcc gccttattac
    22921 tgacggtcat ttccgttttc gttctgttcc agattccgca aattgccgcc agctggggta
    22981 gcggtatcag cgccggagtt gctgacgccg cacgctctac gggttcttcc atgcaggcgc
    23041 ttggcaatat gggcagccac ggcatgtttg gcggtaatgc gttcagaggc ggtaacagtg
    23101 gcggcggcca gcaatcggca ggtggaggaa gtggcagcaa cagcggagga agcagtggtt
    23161 ctaatttaag tggtaaggca aggggcagtc gcgggaagaa ggctgcataa aattaaaaca
    23221 aaagtcgttg aaattgcaat ttcggcgact tattataatt agtacgttca acaaccgata
    23281 atggatgccg taatgcgcag cttattgctt atgggagttc ttctgattag cgcctgttcc
    23341 agcgggcata aaccgccacc ggagccggac tggagcaaca ccgttccagt aaacaaaaca
    23401 atcccggttg atacgcaagg tggtgcaaat gaaagctaat aaaaaaacag ggcttacacg
    23461 tgaagccatt aaagagttca acgaaagccg taaagggctt gaagttgatc tgatggatga
    23521 agtgctgaag tcccggcgta ccgcctggat ggttgccacc ggttcagcgg tggtaactgt
    23581 ttttgcactc tctttagttg gttacgtggt gcataagtac agccagccaa tccccgcaca
    23641 tctgctaacg ctcaacgagg ccactcacga agtacagcag gtcaagctga cccgcgacca
    23701 gacctcttat ggtgacgaaa ttgataagtt ctggctgaca caatatgtca ttcaccgtga
    23761 gagctatgac ttctattcag ttcaggtcga ctatacggcc gttggcttaa tgtccacgcc
    23821 gaacgtggca gagtcttacc agagcaagtt caagggccgc aacggtcttg ataaggttct
    23881 gggcgacagt gaaacgaccc gcgtgaagat taactctgtg atcctcgata aaccgcacgg
    23941 cgtagcaacg atacgcttta ctacggttcg ccgcgtgcgc agcaatcccg ttgatgatca
    24001 gccgcagcgc tggattgcca ttatggggta tgaatataaa tcgctggcga tgaatgctga
    24061 gcagcgttat gtcaacccgc tgggtttccg cgtgacgagt tatcgcgtca accctgaagt
    24121 taactgaggg ctgccccatg aaaaaactac ttctttcagc agtcgttttg tcagtcctgg
    24181 gaggcgcggc cactaacgtt atggcgcttg aggttggccg caattctcct tatgactatc
    24241 gcattaaaag cgttgtttat aaccctgtta atgtggtcaa aattgacgct atcgccggtg
    24301 tggctaccca cattgttgtc gcgcctgacg aaacctatat cactcatgct tttggcgatt
    24361 ctgaaagctg gacgtttgcg cacaaaatga accatttttt tgtgaagccg aaacaggcca
    24421 tgagtgatac caacctggtg atcgtcaccg ataagcgcac ctataacatc gtcctccatt
    24481 tcatcggtga agaaacgaag aaaaatgcag acggtacggt atcaaaatcc tttattgaaa
    24541 cgccgtgggc tgtgcgccag gccgttcttc agctgaccta tgaatatccg tttgagcagc
    24601 aggaaaaagc caaaagcgcg gctgataaaa aacgcattac gcagaagctg aagcagacgg
    24661 cttttgcggg ggcgaagaac tatcagtacg taatgagcga acagcctgaa atgcgcagca
    24721 tccagccggt tcacgtctgg gataactacc gctttacccg gtttgagttt ccggccaatg
    24781 cggagttacc gcaggtctac atgatctcgg ccagtggcaa agaaacgctg cctaactctc
    24841 atgttgtggg tgagaaccgc aacatcatcg aggtggaaac cgtcgctaaa gagtggcgta
    24901 ttcgtctggg cgataaagtc gttggcgttc gtaataataa tttcgcgccg ggcgccggtg
    24961 cggtagcaac cggtacggct tccccggatg tgcgcagggt tcaaattggg gaggataact
    25021 gatggcccgt aaaagtgtcg atgtagatca ggaactcgat gaaaacaccg gagacggtga
    25081 atttgaaagc gagcgtggcg gatttaaagg cagtaaccgc cgttcggctc ctggtatgaa
    25141 agcctttgtc atactgatgg cgctgcttgc tttggtattc atcgggatta cggtcatggg
    25201 taaaattcgc accccggcta aagctgaagc tgataaagac ggtggtaaag cgcaacaggc
    25261 caatacactg ccaaactaca gctttaacag cgatcctgat gttaataaac ctgcaactgc
    25321 gcagaatagc gccactgatg cccgtgctgt gcaggctgcc gcacaggcag atgcagatgc
    25381 gggcagcagc aataccgccg cgcgtacctc taataagcgt aaagaacctt cgcctgaaga
    25441 actggctatg cagcgtcgtc tgggcggcga gctggcccag actaatcagg cggctacaag
    25501 caatagtccc ggagtgcagc cccaggacaa cgaaacaagc gaaggtagtt cagcactcgc
    25561 taaaaacctg actcctgcaa ggctgaaggc tagccgcgct ggagtcatgg ctaatcccag
    25621 cctgactgtt ccgaaaggca aaatgatccc ctgtggtacc ggcaccgagc tggataccac
    25681 tgttccgggt caggtttcct gccgggtttc acaggacgtt tactcagctg atggactcgt
    25741 taggctgatt gataaaggct catgggttga cgggcagatt accggtggta tcaaagacgg
    25801 ccaggcgcgc gtgtttgttc tctgggagcg tatccgcaat gaccaggacg ggacaatcgt
    25861 taatattgac agtgccggaa cgaactcact cggcagcgcg gggattccgg gccaggtgga
    25921 tacccatatg tgggagcgtc tgcgtggtgc gatcatgatt tcgttgttct ctgacacctt
    25981 aacggcgctg gttaaccaga cgcagagtaa taacattcag tacaacagca cagaaaacag
    26041 cggtgagcag ctggcgtctg aagcacttcg ctcttacatg tctatccccc ctaccctcta
    26101 cgatcagcag ggtgatgcgg tgagcatttt tgttgcccgc gacctcgatt tcagcggcgt
    26161 ttatacgctc gcagacaact aaaaaagtgg gcgcttagcg cccgcttttc ttcaggagta
    26221 atcatgactg atgcagcttt ctatcaactt ggcccactgc gcgagtattt agaagatcct
    26281 actgtttttg aaattcgcat taactgcttt caggaagtta tctgtgatac gttcagcggc
    26341 cgcagggttg tgcagaacgc ggcaattacg gcagatttta ttaggaacct tgctaaatcg
    26401 ttggtgagca gcaacaagct gaccatgcag gccattaatg acgtgatcct gcctggcggg
    26461 atcaggggcg ttatctgtct gccccctgcg gtgattgacg gtacaacggc cgtagcgttt
    26521 cgtaaggatt tggcggccga taaaaatctg gagcagctga ccagcgaggg gattttcagt
    26581 gactgccgga agattaccgg cagcaagcaa agcctaacgg atgatgattt tttccttaaa
    26641 gagctgcaca gcagcgaaaa atggcccgca ttcctgcaaa ccgccgttga gaagaaacgc
    26701 actatcgtga tctgcggtga aaccgggtcg gggaaaacgg tactcacgcg cgcgctgtta
    26761 aaatcgctac ataaagacga gcgtgtaatt attttagagg acgttcacga agtcacggtc
    26821 gatcacgttg tagaagccgt ttatatgatg tacggcgatg caggaaagat cggccgcgtc
    26881 agcgccactg atgccctgcg agcctgtatg cgtctgacac cgggccgtat catcatgact
    26941 gagcttaggg atgatgctgc gtgggattat cttaaagcac ttaataccgg ccatccaggc
    27001 ggtgttatgt caacgcacgc taactctgcg cgcgatgcct ttaaccgtat tgggctgctt
    27061 atcaaggcga cccctatcgg ccgtatgctc gatatgagcg atattatgcg aatgctctac
    27121 tccaccattg acgttgtggt gcatatggaa aagcggaaaa tcaaagaaat ttattttgac
    27181 cctgaatata aaatgcagtg tgtgaacggg agcctgtaat gaaaaactta gcaacctggc
    27241 ttctggccgc agcatttacg acagccgccc tgcccgcctt tgcggtggaa ccatccgttc
    27301 aggttggcta ctcgcctgaa ggaagcgccc gcgttctcgt cctgagcgcc attgactccg
    27361 caaaaacctc gatacggatg atggcttatt cttttaccgc cccggatatt atgaaggcgc
    27421 tggtagcagc caaaaaacgg ggagttgatg tgaaaatcgt aattgatgaa aggggcaata
    27481 cggggcgcgc cagcattgcg gccatgaact acatagcgaa cagcggcatc cctttgcgta
    27541 ctgacagtga tttccctatc cagcatgaca aggtgatcat cgtggataat gtgaccgttg
    27601 aaactggcag ctttaatttc accaaagcgg ccgaaacgaa aaactcggag aatgcggtgg
    27661 tgatctggaa catgcctaag ctcgctgaat cattcctcga acactggcaa gaccgctgga
    27721 atcgggggag agactaccgt tccagctact gaatactgac cgccgaaagg cggttttttt
    27781 tgttcaaaga aactgatctc agtatcgcgc acggggcagc tggccaacgt cgccggcatc
    27841 gcgccggcaa aaatcgaaaa acagaaatat cagcaagata gcttaaacag gtgtcgggaa
    27901 atttcgttga gatattttga aggaatcaca gtgtaagcag gcggcctatt tcaaaaaagg
    27961 cggctgtacg gtagtcactg actctctcgc agatcttccc gctcatgtac cagtaatacc
    28021 cgtcagtgct gacaatatcg agcaaatacc gcatatcata aaccgtatcg ggtattacct
    28081 caccctcacc ggccagaacg ccgctggcaa tagaatggtt ccctcctcgt acaaagccta
    28141 tccgccaggg caaccacaaa gtaacgcggt ggttaatatc ctgtacccac ggattgccct
    28201 tagcgctgcc tatatcggct aaagcactcc ggtagcttga ttcatcccac ggccacggca
    28261 ggatcttggc cgtcgcaagc gccaggggaa aatcttcagc tgcaagcctg agtgatttca
    28321 tgtgcgtgta atccatcgcc cagatgattt ttgtgaagaa gaactcgcgc tcgttcatgt
    28381 ccgggcgcgc gtcctggccc tccgtgccaa cggccagcaa ggggtcgtct cagaattcgg
    28441 aaaataaagc acgctagcgg ttgatctgtc aggttgaagc ctgagaggcc gagcgcagat
    28501 cgtcagaaaa ggcgaaaaac gatcctaatc tgacgcaaca taggtggggt gcctgacgcc
    28561 cggttgaggc gtacttcaac tggacaccat tccagaaaga ccaagcatgg catggcctgc
    28621 cgctgtctta ccgtgcttta tttcccgttt tctctatcga cccctatctc atctgcgcaa
    28681 ggcagaacgt gaagacggcc gccctggacc tcgcccgcga gcgccaggcg cacgaggccg
    28741 gcgcgcggac ccgcgccacg gcccacgagc ggacgccgca gcaggagcgc cagaaggccg
    28801 ccagagaggc cgagcgcggc cgtgaggctt ggacgctagg gcagggcatg aaaaagcccg
    28861 tagcgggctg ctacgggcgt ctgacgcggt ggaaaggggg aggggatgtt gtctacatgg
    28921 ctctgctgta gtgagtgggt tgcgctccgg cagcggtcct gatcaatcgt caccctttct
    28981 cggtccttca acgttcctga caacgagcct ccttttcgcc aatccatcga caatcaccgc
    29041 gagtccctgc tcgaacgctg cgtccggacc ggcttcgtcg aaggcgtcta tcgcggcccg
    29101 caacagcggc gagagcggag cctgttcaac ggtgccgccg cgctcgccgg catcgctgtc
    29161 gccggcctgc tcctcaagca cggccccaac agtgaagtag ctgattgtca tcagcgcatt
    29221 gacggcgtcc ccggccgaaa aacccgcctc gcagaggaag cgaagctgcg cgtcggccgt
    29281 ttccatctgc ggtgcgcccg gtcgcgtgcc ggcatggatg cgcgcgccat cgcggtaggc
    29341 gagcagcgcc tgcctgaagc tgcgggcatt cccgatcaga aatgagcgcc agtcgtcgtc
    29401 ggctctcggc accgaatgcg tatgattctc cgccagcatg gcttcggcca gtgcgtcgag
    29461 cagcgcccgc ttgttcctga agtgccagta aagcgccggc tgctgaaccc ccaaccgttc
    29521 cgccagtttg cgtgtcgtca gaccgtctac gccgacctcg ttcaacaggt ccagggcggc
    29581 acggatcact gtattcggct gcaactttgt catgcttgac actttatcac tgataaacat
    29641 aatatgtcca ccaacttatc agtgataaag aatccgcgcg ttcaatcgga ccagcggagg
    29701 ctggtccgga ggccagacgt gaaacccaac agacccctga tcgtaattct gagcactgtc
    29761 gcgctcgacg ctgtcggcat cggcctgatt atgccggtgc tgccgggcct cctgcgcgat
    29821 ctggttcact cgaacgacgt caccgcccac tatggcattc tgctggcgct gtatgcgttg
    29881 gtgcaatttg cctgcgcacc tgtgctgggc gcgctgtcgg atcgtttcgg gcggcggcca
    29941 atcttgctcg tctcgctggc cggcgccact gtcgactacg ccatcatggc gacagtgcct
    30001 ttcctttggg ttctctatat cgggcggatc gtggccggca tcaccggggc gactggggcg
    30061 gtagccggcg cttatattgc cgatatcact gatggcgatg agcgcgcgcg gcacttcggc
    30121 ttcatgagcg cctgtttcgg gttcgggatg gtcgcgggac ctgtgctcgg tgggctgatg
    30181 ggcggtttct ccccccacgc tccgttcttc gccgcggcag ccttgaacgg cctcaatttc
    30241 ctgacgggct gtttcctttt gccggagtcg cacaaaggcg aacgccggcc gttacgccgg
    30301 gaggctctca acccgctcgc ttcgttccgg tgggcccggg gcatgaccgt cgtcgccgcc
    30361 ctgatggcgg tcttcttcat catgcaactt gtcggacagg tgccggccgc gctttgggtc
    30421 attttcggcg aggatcgctt tcactgggac gcgaccacga tcggcatttc gcttgccgca
    30481 tttggcattc tgcattcact cgcccaggca atgatcaccg gccctgtagc cgcccggctc
    30541 ggcgaaaggc gggcactcat gctcggaatg attgccgacg gcacaggcta catcctgctt
    30601 gccttcgcga cacggggatg gatggcgttc ccgatcatgg tcctgcttgc ttcgggtggc
    30661 atcggaatgc cggcgctgca agcaatgttg tccaggcagg tggatgagga acgtcagggg
    30721 cagctgcaag gctcactggc ggcgctcacc agcctgacct cgatcgtcgg acccctcctc
    30781 ttcacggcga tctatgcggc ttctataaca acgtggaacg ggtgggcatg gattgcaggc
    30841 gctgccctct acttgctctg cctgccggcg ctgcgtcgcg ggctttggag cggcgcaggg
    30901 caacgagccg atcgctgatc gtggaaacga taggcctatg ccatgcgggt caaggcgact
    30961 tccggcaagc tatacgcgcc ctaggagtgc ggttggaacg ttggcccagc cagatactcc
    31021 cgatcacgag caggacgccg atgatttgaa gcgcactcag cgtctgatcc aagaacaacc
    31081 atcctagcaa cacggcggtc cccgggctga gaaagcccag taaggaaaca actgtaggtt
    31141 cgagtcgcga gatcccccgg aaccaaagga agtaggttaa acccgctccg atcaggccga
    31201 gccacgccag gccgagaaca ttggttcctg taggcatcgg gattggcgga tcaaacacta
    31261 aagctactgg aacgagcaga agtcctccgg ccgccagttg ccaggcggta aaggtgagca
    31321 gaggcacggg aggttgccac ttgcgggtca gcacggttcc gaacgccatg gaaaccgccc
    31381 ccgccaggcc cgctgcgacg ccgacaggat ctagcgctgc gtttggtgtc aacaccaaca
    31441 gcgccacgcc cgcagttccg caaatagccc ccaggaccgc catcaatcgt atcgggctac
    31501 ctagcagagc ggcagagatg aacacgacca tcagcggctg cacagcgcct accgtcgccg
    31561 cgaccccgcc cggcaggcgg tagaccgaaa ggggtcgata gagaaaacgg gaaataaagc
    31621 acggtaagac agcggcaggc catgccatgc ttggtctttc tggaatggtg tccagttgaa
    31681 gtacgcctca accgggcgtc aggcacccca cctatgttgc gtcagattag gatcgttttt
    31741 cgccttttct gacgatctgc gctcggcctc tcaggcttca acctgacaga tcaaccgcta
    31801 gcgtgcttta ttttccgaat tctgagacga ccccagcaag taatcggcct gaattggcag
    31861 tatcagcgcg cgtagtaagt catggatcgc cggttgcggc agtctgcgcg ccagattaat
    31921 tacccggtcg aacttcagtt tatcctgctt gcgcttgtcg gtctgctcca tcagatttca
    31981 tggccccctt cttcatgctc atgctcatgc tcatgggtgt gttcttttcc ggtatggctc
    32041 tgttccgcct gagacgtctg cggcatggcg taatcgtcgt aaatgctgct gtcaaagtcg
    32101 tagtctgatg cttcggcata atgctcgtaa tcggcatact cctgcgcgct ccactgctga
    32161 tcgtcggcag cagcataatc atgggccagt tctgcatcat tttgctgtgc ttcatgacgc
    32221 cgcaggccaa cggaatcatc catagggttc tgcttaagat gaaaggcgtc ctctgcgttg
    32281 ctcaccggct gataatcagt gccggttgtc atgttatgtt catcgggttt ctggttaaac
    32341 gccatgcttt cccccgtggc ttctggcaga cctttttcag ctgatcgggt ttctaaactg
    32401 gtatcgcggc caatatcctt aaacctggcc tcaagcccaa agaaacggtc aatttctgcg
    32461 gccgtggttt tcgggctgtc gcggctcacg ctcgatgcca aagatttttt atcgtcggta
    32521 aaaatttcca cctcatgacg cgcacgcgaa ataccaacat aaaaaacgtc cttagaagtg
    32581 gtaagcgatt tggtatctat gttgaacaac acgcgatcac aggtaagccc ctgggatttg
    32641 tggacggtgg ttgcataagc ataggaaaga taagaagcct gttttttgtc cagctcaacc
    32701 gtgcgccctt ttttgtcctc aagcgtcagt ttttcaccct ccacggtttt caccgtgaag
    32761 cggtcgccgt tggcaacgtc cagcgtttta tcgttacgcg ttaccataac cttatcgccc
    32821 ggcgccagtt cggcgctgac tgcctggtat acagacagct tggtgtgtgt acgcgggctg
    32881 aaagcgatct gctcaccgct gctgctttca accgtcaatt tgttgcccgg cccggtatca
    32941 agaacctggt aagactcgcc ccgcttcata ccatttttgt aatcctgttc ggggataatg
    33001 atttgccctt tactgaaata acggctgtcg cggcgttccg cctgtgtcga atccacgcgg
    33061 tcaagtagcg tgaacgtttc gccggttccg gcaagcccca gattgccccg gatgtagtca
    33121 ttgagggttt tgcgtgaggc gttcgtacca gagattatca gggtggcatc ctgttgttct
    33181 gaggacagag acaggtagcg atcggctagt tgagagagtc ggggcgcttc ttccttcagt
    33241 tcgttcacgc cggtgatatt tttcagggcg cgcgcggcat taccttcagc ggcatactta
    33301 accgcctcaa gcaaaacttc attcttctgt cgctgaatgt ctttcatgta gctggtctgc
    33361 atacctgctt taatcagctg ctcaaaaggc ttaccggctt ctaccgcttt cgtctgtgac
    33421 gtatccccca ggaataccgc gcgagcgtta tgcttctcga tcacctccat cagctgtttc
    33481 atctgtcggg cgggtataac cccggcttca tcaatgaata cgactgattt ttcatccagc
    33541 tttttatcct tcgctttgag gaaagcggca acggtgcggg ccggtaatcc atcatcttca
    33601 agcgcttttt tctgtgtccc atagggggcc agcgccgtga ccttcagccc ttgtgactcc
    33661 agcagctctt tagcggccat cgtcatatag cttttaccgg taccggcgta accatgtgcg
    33721 gccacaaacc gatctttgct cgtcacaatt tctgtaaccg cgcgcatctg ctccttcttg
    33781 agggttttcc cggcaagcag ctggcctgca atctctgcgg tcagctgtcg cggcatctgc
    33841 ccccggccgc gtgattcgat agtcagaatg gaacgctcaa ggcgaatacc ctccacggta
    33901 gtgacgcggt ggctggtctt tttaagcctg ccgtttttaa taccatcatc taccgcaaaa
    33961 cgggctttat ccgcacgcat cccgctattc gtcagcgagt cgatccactc tttgcgcgtc
    34021 agagtttcgg ccataactga agcaccgacc ttcagagttg attgataccg ggcttcgccc
    34081 tcgatgatgg cgcccttctg taccgccttc aggtacgctt tttcaacatc ggctattgtg
    34141 gcatggccca gcacctgctt attagcgatt tgaatcagct tctggcgttc aaagctggca
    34201 tcgcgctctg acagcgactt aactgcaaac tggatagccc ggtcagcttt aacctccggg
    34261 ctggtaaaat ccggggccat gttgcgcgct atatcagcct ccagaggttt accgtgtccc
    34321 tgccattcac ggttatcaaa atcaatgccg agcgttttgg cgcggctggc ccattcctgg
    34381 tgaatttctt cacgggaatg ctctgttttc ttttcacgcg tagccatcga gacgcggctt
    34441 ttcgtctgag catcggcggt ttcccgcgtc agccccattg cagcgagtcc cttttcaatt
    34501 tgctccgacc ggcgggaaaa agcgcgaatc tgttcatctg aaaaatgggc catatcgaac
    34561 gtgttatttt tgctgttgta acgcagctca taaccggctt tggtcaactc caacgccagc
    34621 tcctgtttgt aaacatcgcc caggtgcatt ttattacgca tcagctcatc atttttgagc
    34681 gcgcgccact ggccgtcctc gcgctgggtc atgttcatga caaaagcgtg tgtgtgcaaa
    34741 tcaggatcta gcgccctgga cgtttcgtgg cggaaagtag cgacgacaag gttattggta
    34801 ttctgggtta ctgatttccc ctggcgagtc gtccgggcct gcgcgagttt ttcagcttca
    34861 cgcacagcag cggcaacagc tttttcatga gcctcgataa tggttttatc gccgtgtatc
    34921 agcgcctgca tggatacccc tttaggcgct gaaaacgtca ggtcgtagcc cagacgctct
    34981 tttttggcat cacccacgtg tcgctgcata tgcgtgaagg tatctatctc accgacaagc
    35041 agctctttaa accgggctga ttcaacgtcc ccggataagc cgagggcttc agctccggtt
    35101 ccctgccagg acgtgaatga tgaatcctta ctgtagtaat catcctttgc atcagagtag
    35161 tagcccacaa cgctagtgac gttctggcgg gtaatcgtgg ttatatcaag catcagatat
    35221 ccctcagttc aatgccagga acagggtttt tgcgatggta tttaacgtgt ttagccttga
    35281 acttagcgac gggcatatca ccaggcaacg ccagatagcc ggtgaggttt ggcaacattg
    35341 atatttcggt aggcgttacg gcacgaacaa ctttaacgtc gcggcgttta cggacaatcc
    35401 agggcttctg aggatcggat tctttacgct caacttcgcc ttctatctca ccgagtgagc
    35461 gcgacatttg atccaacgtt tcatcaccga gacggctgcc gcccagcacg atgttagaac
    35521 gcatgttagc cagaattgtc tgagccatat cccgaccata aaccttaacc agctgagaat
    35581 aggtttgata gccagcataa acacacagac cgcttttacg ccctttggtc agtgcatcgt
    35641 tgaggtttgg cagaaactgg agtgattcca gctcgtcaat aaatacatta atgcggcttt
    35701 ctttttcacc catacccagc acgatagaaa aaatcgaatc cagccagcag gaaattagcg
    35761 gattaagtga ccttttcatt tcttcctgcc aggtgataaa caaggttccc ggctttccat
    35821 catcaagcca gtcacgcagg gaaaaattac cttccggcat tttcaaatgt ggggcaagat
    35881 tcttactgag aacaaatcgc gcgcttccaa ctgctttttc agacccggaa aaaatagctt
    35941 cggcaggcgt ccccattaaa aattctttta attttttctg gtcaacgtta caggcccagt
    36001 gaataacttc ttccatagtt actgtgctgt ataggctgtg aagttttttc gaaacttcac
    36061 taaaaataag acggccatag ccgaaccatt cttcagtagc catatcaggg ctttcctgaa
    36121 caatagagtt cactaagcgc tcgtaatcat atgaacggcg aatttcattg aaaaacaccc
    36181 agccttcagt gcgtttatca taggcgttta aaataacatc gccgggacga tagaaattct
    36241 ttaagaaccc cccatttgga tctaaagcaa tatttttgcc gcctctaatg atgctcttaa
    36301 ataacagttc attgaaaatt gtggttttac cagtaccggt tgtaccggca atcgaaaaat
    36361 gcaagttctc agcgtatgta ggtatgggga tattagccac ggttaactgg ttgacacctc
    36421 tttcgcgtgt tttatcagcg agtgttctgg cgctaacaag ctctgtacca cgataaatct
    36481 ttttgaatct ttcgccttta aacacgcgtg atttatcata aatgataaaa gcgatcagac
    36541 cgccaacacc aataaaccag ccagcaatta aagctgacca taaaggccat agcgaaaaag
    36601 tattcttaac cagatacgga atcaggtatt tagccgtgga tggatcaata ccgtaggtaa
    36661 attttgcaac tagaaaccat accatcactg gaggcaaagt aattgcaaat aaaaatgcta
    36721 agcctctttc tctatcgtcc atttcagcgc tccttttttg gttcccagac tttgtagccg
    36781 ttacgttcaa cctctgcttt tgccgctttg gttttgcccg gttctgctat cgagcgcagg
    36841 aggattagcg tttcaatagc gagtgattca tgcaacatca tctgtcctgc cggtgggaat
    36901 tttacgccag atagcgtttc ggttattgcc ttcagctcat cgcgcagtgg gccaaaatcc
    36961 gcatctgaag cacggtcaaa aagataatcc agtttgcgat ttacgtcgct cagccggtcg
    37021 gcaactattt tcaacccgga ctcccgatca cctgggccag cttcaatgca gcgccgcaga
    37081 taatctgacc gattacctcc tgaaaccagg tctatatagg ccaaaagttc atctgatact
    37141 tttgcggtta ttattggcat tcagtcctca cattgtgcat tttttaaaca aaaaattggg
    37201 atctaacaag ctgaaatctt agtattacca aagtaataaa gcaaactcat tataaaacaa
    37261 tgagttattg ggtgttttta atacctaatt attaccgaat attgttgcta tttatttttt
    37321 tatcttttaa atcagtatga tagcgtgatt tatcgcgctg cgttaggtgt atagcaggtt
    37381 aagggataaa aaatcatctt ttttggtagg ggcgatctac gtaggttaag gactaactgg
    37441 ctaaaaagcg ttcaatattc cgtattcatg cttgcatgaa taccagtaca acaaaagtac
    37501 atcaaaatta catcaaaatt acatcacttg aaggttgaca gtacaacaaa attacatcat
    37561 tctttggtca tgaggtagcc agtacaacaa aagtacatca aaagtacatc aaaattacat
    37621 caaaattaca tcattctaaa tgagggtact atgaagccca aaagtatcag ggcggcactt
    37681 cagttgatgt tgccggaaat agaagaaatg ctgtcactgg gagtttccag ggaggaaatt
    37741 tataaggcag tttctgaacg cttcggcctg gaaggtgtga acgttcgtag ctttgatacg
    37801 tccctatata gagcgcggca aatccggaaa aatggaatgc acaatacaca tgaaaggatg
    37861 ccgaacaatg atgatagtgt attgcacaat acacaaaaag gaggtagcga gaaaggtgca
    37921 gaggaaagtg tattgcacaa tacacaaacg ccgcctgagc ctgaaccgca aggaagtgaa
    37981 aaaaaagaaa gtcccggcat tattgataaa gagttcttca ataaaatcag tgaagatttc
    38041 gaccctaaga tgttcaataa aaaattctga ggtgatttat gaaagtagcg gtaattaatt
    38101 acagtggcag cgttggtaaa accttaattt catcctacct gttagccccg cgtctgactg
    38161 gagcaaaatt ctatgcggtt gaaactatca accagtctgc ttccgatctg gggattgaga
    38221 atgtttccat ttttaaaggt gatgactttt cacggttgat tgaagatatt gtttttgaag
    38281 atgccgggat tattgatatt ggtgcgtcaa acgtagaagc gttcctgatg gcaatgtccc
    38341 gctttgacag tggcgcgaat gaatttgata agtatgtaat cccggttacg cctgataata
    38401 aggccattga tgaaagcctg aaaacagcac atacgttaag taaggcaggt gtaagcagcg
    38461 ataaaatcat ctttgttcca aaccgcatta gtccagatag tgaagtagag gatgtactgg
    38521 cgccggtatt tgaatttgtc aaacgaacga aagttggcaa aatcagcaag aaatctgtta
    38581 tttataacag tgaagttttc gaatatctcg cgtatcaccg tatctcattc gaagcattga
    38641 ccgctgaaga tccagaagaa tttaaagccc gcgctaaaca aacaacggat gctgacgagc
    38701 gcaaaaaact ggcccgccgt tatacctaca tgaaacaggc aattcctgtt aaagctaatc
    38761 tcgataaagc atatgcggct ttaatgggag aataaaatgg aaaagcagcc agataaattt
    38821 gaagttctga tggattggtt tttaggtgac gcgaaggaaa tcaccgcaag tcagaaagaa
    38881 atgactgaga tactttctgc gctttcggaa aagctggcaa aagacaccga aagtttagga
    38941 gagacggcag actctcttaa acggacttta gtagaaaacc agcgttcaat tagcctggca
    39001 attagtgatg atgctaaggc gcgtgaggaa tttctgacga agttccgccg cgcgcaggcg
    39061 tccagagctg agacgttaac ccgtcagatc ctttttatta cagctggctg cactattgtg
    39121 ggcgccgccg tgggtgccgc gatagccata attctactga gataatgtaa accgggcatg
    39181 tcccggtttt ttttcaagcg aagcgcggag gccgcaggcc ggaggcatta gtggccgccg
    39241 cccgaagggg cgagacgcgt agcggctcga tgcgcagcac ggcagaacgg ccccgcaggg
    39301 gtaatgcccg gtttaattca acgtgacagt cacgtggagg aaaaatatga atgaccgaca
    39361 gcgtgaacaa gcccgtattc gccaggcccg gcgccgcgcg cgactcaaag aggaaggcgc
    39421 tagcgtgaca gtcacgctaa caaaacagga agaagcaatg ttacaggagc tttgccgggt
    39481 tcgtcgtcca ggacgaacag cctattccac gaatgagttt ttccaactgc tgctgatccg
    39541 aaactggcaa cagtggcagg agcaaaaggc gcagctgggg aaatgccagg cttgcggaaa
    39601 gctgaaagcg gagggaggtt gcggcggcga acggcagagc gaaaccttta actgctggct
    39661 agccgtcgaa gcaaacgagc ttaatgtgta gtgtattgtg ctatacagaa attgccaaaa
    39721 gcagcgcgga gtaataactg aaacggccgc gcagcggaaa gaaaaaagcc cggtcaatcc
    39781 gggttttttt ctttcggcgg ctcagtaatc gtctagatct ccgcagccca gcgggcaaca
    39841 attacgctca ataccgtggc tgcaataatc gttttcccga tcctgccgga tttcttccgc
    39901 gatctcgtct tgggtcagat agtcaaattc acgccgcgct accgcgatca gttcttcccg
    39961 atactcggcc ggaacgccag caagatagcc gtcaataacc gcgctcaggc ggcgctgata
    40021 cagttcataa atcaggccgc agcggggctg ctgttcgcgc gcaaaactct cacactggcg
    40081 acgaaaatct tcaagagtct gctcaagggt ttgtgtggtc atgtcgtttg tcctcgatct
    40141 ttctgttaaa gacccggctt ggccgggtcg tcagtgctat ttagtttgtt gcagcagctg
    40201 gtctaatttt gccgccagtg catacgtcga tgtgaaagcg ccttgcaggc gctgattagg
    40261 cagctggttg aacgcttcga ggcaggcgcg cagcaataat tctttctgag attcgacttc
    40321 ttttttcagc tgggaagggg tggtaacagt ggtcatgctt actccttagt gatccgatac
    40381 cggcaatttt tcgggtggcg gtattgcctc ccgatgattt aattatcggt gattacgcct
    40441 ttaaagtcaa tataagtacg gaatttattt acatgttttt atgcccgtca gggcatggaa
    40501 ggcgaccgcg ccggactcca ccggacaccg gccgcaaatc gccggaaact gcgggactga
    40561 ccggagcaac aggccaaccc cccttcctgc taagccataa cccagcccgc cgccacgcag
    40621 ctgccgcacg tcccccacgg gggtgcgcag tgggcgccgc gcgcctgcgc gcgggtacag
    40681 cggcccgcct gcgggtcgcg gcgccgtact gcgagttagc ggccgccgcg cggccggtta
    40741 cgggggacac cgcaccgtca cggccagcgc cccgctgagc tgcacaatcc acggataaca
    40801 caatagcgca ctggcaaagg atgccgacgc ctgaagggcg ttggcacccc gaaggggcgg
    40861 ggcgagacgg gaaccggctc gatgcgcagc acagcagagc ggccccgaag gggtaacgcc
    40921 ctgtgtggca tcaggattta gcgcaatggc agaacatgag ctggagagat caccggcaag
    40981 cagcagcaaa ggggcggcgc agccgcccag atggctgttt gccgataccg gcgattaatt
    41041 agagcggtgt ttaatatccc ccgcgtggcg ggggactagg tttcagcaag tcatgttaaa
    41101 tacgtgtccg tcatgtaaac tgaaatcccc aataaacaga tcccgcgcat aggctacgat
    41161 gtcaaaatat cgggctacgg attcaggaat ttcattcagt agaccgctat cattcaggta
    41221 ttcctctgca aaagtttctt cgtccttagc ttcgcccata taggcatctc taaacaggtc
    41281 gaaatcagtg ctattaaaca gatcaacaaa ggccacaaac gccgcttcgt ttccttcctc
    41341 gcgggcttgt ttaaagccgt taataaaatc ccagttgata tggcactctg acgccatatc
    41401 agacggaata ccctcccaat cctggaacat aaattctgga tcagcctcat ttgcgtgtaa
    41461 ctcgcggcag cgctcgtaaa actcctctga gctatcaaaa tcggtcagat cgagccaggc
    41521 tcccgcaatg cttccgcagt tgtatttatg gtaagtgcca acataaacag aaggggtcgt
    41581 aatatcagtc atggtgtact ccttaaagcg ccgataccgg caatttttcg ggcggcggta
    41641 ttgcctcccg atgatttaat tatcggtgat tacgccttta aagtcaatac aagtacggaa
    41701 tttatttaca tgtttttatg cccgtcaggg catggaaggc gaccgcgccg gactccaccg
    41761 gacaccggcc gcaaatcgcc ggaaactgcg ggactgaccg gagcaacagg ccaacccccc
    41821 ttcctgctaa gccataaccc agcccgccgc cacgcagctg ccgcacgtcc cccacggggg
    41881 tgcgcagtgg gcgccgcgcg cctgcgcgcg ggtacggcgg cccgcctgcg ggtcgcggcg
    41941 ccgtactgcg agttagcggc cgccgcgcgg ccggttacgg gggacaccgc accgtcacgg
    42001 ccagcgcccc gctgagctgc acaatccacg gataacacaa tagcgcactg gcaaaggatg
    42061 ccgacgcctg aagggcgttg gcaccccgaa ggggcggggc ggccgcttgc ggccgggcga
    42121 gtccggcgca gggtgtggcc tgccaagcgg agcgcggagg ccgaaggccg gaggcgttag
    42181 cggccgctgc ccgcgtaagc ggggcgagac gggaaccggc tcgatgcgca gcacagcaga
    42241 gcggccccga aggggtaacg ccctgtgtgg catcaggatt tagcacaatg tcagaacata
    42301 aactggagag atcaccggca agcagctgca aaggggcggc acagccgccc cgatggctgt
    42361 tacttgtctt tgtcgcgtag cactttgatt aggccggtta cggccgtaat cagagcggcc
    42421 agcgaggtga tgatttgcgg taggttttcg aggatggtag aggtcatata gcacctgtag
    42481 agaagttggc ggggtgtcgt ttccgacggc cgcactgtaa ccgggcgaat aaggcaggtt
    42541 gtcaacagct tgagcgaagc gtctgttgac aacctgccgc gcccggtttc actgcggtca
    42601 taggcggaac gacccacgcc aacggaacgg ctttatgacc gggcagctga gataccggcg
    42661 aacctggctg gcggctgacg ccagccgcca agcgccagcg cggagggcga agcccggagg
    42721 ccaagcggag cgcggaggcc gaaggccgga ggcgttagcg gccgctgccc gcgtaagcgg
    42781 ggcgagacgg gaaccggctc gatgcgcagc acagcagagc ggccccgaag gggtaacgcc
    42841 cggagtctgc cgctgtttat ctctcgttcc atctgaaatc ggcggtaagg ccattaaaag
    42901 ggtcagttta tcaggggggc gttagccccc catgttgtta atcatcaggc aatatcgtct
    42961 ttgtagcagg cataaccgaa gctaagctct gttttcatat agtggcgggc aaagtcccag
    43021 gcatcgtggc cgaagtcctc ataatctgcc aggacgattt cgcgggcttt gtgccattgc
    43081 tgtacggaag aaagcggcag aacagggcag ggaagcgacc agtcagtgac ggtgttgcag
    43141 atcatatctg ccagacgctc cagggagccg taaaccagct ctgtgcgcag atccgccacc
    43201 atgcgttgtt tacgcagtga tgccagataa tcaatctctt tggttatatc agaatttaag
    43261 cgggtctggt aatccatgat gtactccttt gcgcgccgat accggcaatt ttgcgggcga
    43321 cggtgttgcc tcccgatgat ttaattatcg gtgattatgt cctcaaagtc aatataagta
    43381 cgtaatgtgc atacaaaatt ttatatcttg caaagcgttc atagagtgcc tgaatcgctt
    43441 tctgacagcc tcaataaaaa aggcggggat tacccgcctt ttttcttaca gctgcttacg
    43501 tggcttttta cgcgtcatat acaacggtat cgcgcagtct accgcgtaca aaaagcacgc
    43561 cagcgcgccg caaccgtaca gaaacgcaag cggcttatta tcgaagtagc tgaaaacccc
    43621 tgtcgccgca cacaggccca gaacagagac gcaggcgcag gtgatctgca ccagatccct
    43681 gtatcccgca cgaacgataa accagggcag ggcaagcgca gcggcgctaa aaattaatgc
    43741 gagagggaca aaaacgagat agtgatacat gtgaactcct tgatggttgc cgataccggc
    43801 gattgttcgg gcggcggtat tgccacccga tgatttaatt agaggttttg cgcgtccagg
    43861 agattgacct gagccggggt aacgtgaaac ttttcccctt tatggatcac gttatgcggg
    43921 gcgctaattt catcactgat aaagctaacc gggtaacgtt ttttaccgca aatccgctcg
    43981 ctaaaccacg ccacttttgc cgctggccga tccactggat gaacaatcac accggccatg
    44041 ctgcaacccg ttgcgggttc gtccagcgta atgcttaccg ggactgtatc ccggtaaaaa
    44101 aacttaaccg gcggcacacc tgcctgcgta gcggctgcga caactgcaag cccgataacc
    44161 gctatccgat taataagcat tttattcccc ttactcatgc tgatatcacc ttgccagctg
    44221 ttaccagttt acgaaattcg ctttcatgaa tttcacgccc atgctcaagc gttgaataca
    44281 cgttgccgat aagccagtta ccagccgttt ttgtctcggt ataccaccat gcttctgtca
    44341 gagtaagcag cggttcgcta tcctcgccct tctcatagat ccagatttta gtgacgtctt
    44401 tacccgtttc gttgctgccc tgaatggtag ggtcaaaggt atgttcaatc tctatatcga
    44461 agtaacgctg aaggaagtta gtaaagtgca tgacgactcc tgtaagcgcc gataccggca
    44521 atttttcggg tggcggtgtt gcctcccgat gatttaatta tcggtgatta cgcctttaaa
    44581 gtcaatacaa gtacggaatt tatttacatg tttttatgcc cgtcagggca tggaaggcga
    44641 ccgcgccgga ctccaccgga caccggccgc aaatcgccgg aaactgcggg actgaccgga
    44701 gcaacaggcc aacccccctt cctgctaagc cataacccag cccgccgcca cgcagctgcc
    44761 gcacgtcccc cacgggggtg cgcagtgggc gccgcgcgcc tgcgcgcggg tacggcggcc
    44821 cgcctgcggg tcgcggcgcc gtactgcgag ttagcggccg ccgcgcggcc ggttacgggg
    44881 gacaccgcac cgtcacggcc agcgccccac tgagctgcac aatccacgga taatgcagga
    44941 gacgaatcat gataggaggc tgaaggggaa atgagcggca gcaggggaag gggttgccaa
    45001 gcggagcgcg gaggccgcag gccggaggcg tcagtggcag ctgcccgcgt gagcggggcg
    45061 agacgcgtag cggctcgatg cgcagcacag cagaacggcc ccggaggggt gacgtccggg
    45121 ggttcgcttt taaagatttt cgaccacatc agtaaatcgt agtgacacca tgaagcaaaa
    45181 gtatcgtgca gaccagaatc aacaacagta acagcagacc tttttttcga cgtaataaaa
    45241 ccggccccaa agcgcccgca agaagcacac tcaacacgat ttccgttatg ctaatcgtat
    45301 tcataatctc tcacgtttcc ctttttagaa ctctgccaca cacggataaa accttataac
    45361 aaagcaacaa aacccgttat tcagacacgg taatgcctag tttttttgcc agaatttcag
    45421 atgacaaaga aacccttatc gacttcccgg ttacaaggtg aatgattgtg gcttcatgcc
    45481 cttcaacaga gtgggatatt aactcacgct gaatgatatg cgtctctcca tcatttcccg
    45541 tcacggctat taggctctct gtagaacagg ggttgatact actaatgttg gtgttgtttt
    45601 cggttttgtt cagcatcgct gatcctcaaa tatcggtttg tgttacgtct gccgctttgc
    45661 gctggataag cgacttaaag aaatccgacg ccttcagaat atcgctatcc tggaagtcgg
    45721 gaaatgtcgc ttctgtcagc tcctgcgccg tacctgcccg tataacggtt tcatcgcgga
    45781 tcatcgttcg cttaacgcca tcagcctgtt ttttgctgaa ggagtgccgg aaaataatcg
    45841 cgtattggcc gccgctatcc tgatgaacag aagtatccca gcgatgatta ccctgtttac
    45901 gatagtggtg atagatttgc tggccgtagc gctcctgatc ggaattacgg taatcgaaca
    45961 ttaacagttc caaaagcatt aaccgatctg gcaattgcca ggcggtaggg tgttgaagtg
    46021 tcgctaacat agtttcccct gagcgtgaca gtcacgataa ggcgggcttt gcccgcctgg
    46081 ttatcagtta atcaatggca cgataaatac gattctggct ttcgttctcc agcgtattaa
    46141 cgtactcccg caacaggtga taccggttag ccatcgtttc gttcagttcg gctttgcctt
    46201 cttcatatgc cagcccgcaa aagtaactgt aggcatacag acaaacaata atccctactt
    46261 cgcgcgcgct gcattcacct tcaaaatagt taggtaacga gagccaaaga ggttggggcg
    46321 cttccataaa aaacgcgcca ttgctggcct gaaggtattc ccaataccct ccctggtagt
    46381 ctttagcgta acgattcaga aaggactgaa tgaagtgatc tgcgctgaag aaagcgccac
    46441 gaaatgccgc aggcatgaag ttcatgcggg cgttttcaga aatgtagcgg gcggtgattt
    46501 cgatagtttc catgatactt cctctttaag ccgataccgg cgatggttaa gcggcaggca
    46561 catcacctgc cactttttaa ttatcgtaca atggggcgtt aaagtcaata caagtacgga
    46621 ttatatttac ctaattttat gcccgtcaga gcatggaagg cgacctcgcc ggactccacc
    46681 ggacaccggg ggcaaatcgc cggaaactgc gggactgacc ggagcgacag gccacccccc
    46741 tccctgctag cccgccgcca cgcggccggt tacaggggac actgagaaag cagaaagcca
    46801 acaaacacta tatatagcgt tcgttggcag ctgaagcagc actacatata gtagagtacc
    46861 tgtaaaactt gccaacctga ccataacagc gatactgtat aagtaaacag tgatttggaa
    46921 gatcgctatg aaggtcgatt aggaatactg caagtgtaaa tcagataatt acaataaaaa
    46981 caaacaacct aataattaaa tgccttaaac attatttaaa ataaaatagt ttacataaga
    47041 aattgttatc tattaccttc ctgaagctaa gatatttggt ccagaaaaaa gagcggaatg
    47101 atagaaagag atgagggttc gttgcaagac aagactgaag ttcaggagca catttttaac
    47161 gtaaatggag cgatacctcg ctccatttat tgcatcagaa accgtgggtt acgattttcg
    47221 ccgccgcagc cagaatatcc cgacggcttt ccgccttctg ctccggttgg gtaaagtagg
    47281 tcaccagaac cagcggtgcg tggttttccg gccagataac cgcgatatcg ttggtggtgc
    47341 cataatctcc gctgccggtt ttatcgccca ctacccatga tttcggcaga cccgcccgaa
    47401 tgctcgcgct accggtagta ttgcccttaa gccacgtcac caactgtgcc cgctgagttt
    47461 ccgccagcgc tttacccagc gtcagatttt tcagggtctg cgccatcgcg agcggcgtgg
    47521 tggtatcacg cgggtcgcct ggaatggcgg tattgagcgt gggctcggtt ctgtccagac
    47581 ggaaggtctc atcacccaac gagcgagcaa acgccgtcac tttatcggga ccacccagat
    47641 gggcaatcag cttattcatg gcagtattgt cgctatactg cagcgccgct gcgccaagct
    47701 cagccagcgt catcgtgccg ttaacgtgtt tctccgcaat gggattgtag ttaaccaggt
    47761 cgctcttctt gatttcaacg cgctgattta gcaggtgctt atcgctctcg ctctgtttaa
    47821 gcaccgccgc ggccgccatc accttactgg tactgcacat cgcaaaacgt tcatcggcac
    47881 ggtagagaat ctgcgaatta tcggcggtgt taatcagcgc aacgccaagc cgacctcccg
    47941 aacttttctc cagggcttcc agctgctgtt gcacgctgtt cgcctgcgca tgcagcgttg
    48001 cgctgctaaa tagcaggggt agcgtcgcca tcaccgttaa cattgagcgg cgaatgctct
    48061 gagtcatcat taaaaatcct ctattagtat tatcccttgg ccttcaagta ttcattgaac
    48121 ctaaattcca cgtgtgtttt ttattagctt caaaaatcac tatttcacga agaatttaga
    48181 ctgcttctca cacattgtaa cattatttac aaccaccttt caatcatttt tgataaatca
    48241 ttgatttcat ctttgttgca atgatactta ataaactctg caagttatcc acagagcaac
    48301 actcaatttt attgatgata ttcttattat accagacatt tttcatacac tcccttgtac
    48361 ggatagtttt ccgacaactt catgattaca tatcttgcgg ttttgattat ttttgctgca
    48421 agaaatacat acttcaaacg aaaggtcttt atttgctgtc tgtattctga agagtccaag
    48481 gaatcaaact tgaacaacaa aaataggtta tatgaaagca tcatcatttg aaacacggct
    48541 tcattcgccc aaaatgactt tagcaagaga tgacccaccg ccatgtcgta tttggcttct
    48601 ttgatatagt tttcagcatt accacgcttt tcatagtata taactacttt ttcagaaagc
    48661 aaggtagtat ttgttacaaa gaaaaagtag tcgtattcgg aaccttctaa aagtgataat
    48721 tgtgctcttt ctttttctgg tttcagtacg cgagatacga caaatcttct gtctttttcc
    48781 catttaacta attttgtata cagttctgta gtttctctac cttcttctcc tttaacgaat
    48841 acaattgatg aattcgttgc ttgtgaggtg agtgtagaat aacttttggc tttaattaaa
    48901 tatttgcatc caagagattc tatcgtttcg ataatttttt catcaaagta gccactatcc
    48961 attcgaaata aaatttctaa atcgtctgat ttgatgttag caacaatttc tttgatcatt
    49021 tccgcagcac cgtttgcagt gtaagtattg ccacttctta caaatccggt aacatatgct
    49081 tttaattcgt cgcaaaatgc aaattggata ttgtagcatc ggtttcccag tttcttagga
    49141 ttatatcctt ttgacgcacc ttcttgatga ccttctacgt taattacact actatcaata
    49201 tcaatcgtaa tggatgtcaa tttactttta gtgagcagtt ttttaaagac tttaaaatta
    49261 atgtctctaa acatttgggt tgtcttgaag ttgaagtttc ctagaaaccg tgacactgtt
    49321 tcaggttctt ttacggaaat atcaaactcg ttgacgaggg gatcattttg aagtagcttt
    49381 agacgttcta acttatcaat gccaatgaag tgaccgcaga gcatggtctt tatatgattc
    49441 atcttgattt tatttgttga gtcattatca aatacgaggt cattttcaat aaaatcaaaa
    49501 atcccattgc tttttgcatt ctcaaggagc agaaaaagac ctgcatttga tgttagattc
    49561 ttagctttga aatcaatttt attaatcata attagaaccc ctttttacta cttttcttac
    49621 tacctagatt ctacgtcagt acttcaaaaa gcataatcaa agccttgata aatatgcatt
    49681 ccttcgaaat tcagctttca cccattgggt gaaagaaaag tgctcaaaaa tatgttaaat
    49741 tatcagcttt tatgactcga tatatggtaa aataatagta ctgaaaaact gcgtaatgag
    49801 cggcaatact gccgcgtcat aagcgtcttt atccgcacca gtccttattc agtgcgtgat
    49861 acacagtatg ccaatcaggc aaccgaaaaa ctgacggtgg caacccagga cagccgcacg
    49921 ataattcagg cggcacaagc cgcgctggcg cggatctggc gggaagatat tgcgtatgca
    49981 aaagcaggga tcatgctggc cgatttcagc ggaaaggagg cccagctgga tttattcgac
    50041 tctgctacgc cttcagctgg cagcgaggcg ttaatggctg ttctcgatgg cataaaccgg
    50101 cgtggcaaga gccagctgtt ttttgcaggc cagggcatcg ataactcctt tgccatgcgc
    50161 cgtcagatgt tgtcacctga ttacacgaca gactggcgct cgataccaac agcaaccatc
    50221 aaataattac cggcgccgca cgcgggccgg tcaacccctc aaccggccga aacgagtttc
    50281 ggcgcggttt cgcggttttc ggtaaaaggc gtttcatctg tataaaagat cagctaaatt
    50341 atgtgtattg cacaatacat atatgtgagg ttaacagtga atttgcctac gcccgaaacc
    50401 tacgatgaac ttcagagagc ctacgatttt tttaatgaga agctattcag caacgagctg
    50461 ccgccatgcc tgataacgtt gcagcgtgag aagcgaacgt atggctattg ttcctttaag
    50521 cgtttcgtcg gccgtgagag tgggtacacg gtagacgaga tcgctatgaa tccggtgtat
    50581 ttctcgatca gaaccataaa ggccacgctt tcaacactgg tgcatgagat ggttcatcag
    50641 tggcaattcc attttggcga gcctggccgc cgtggctatc acaacaaaca gtgggcggcc
    50701 cggatggaac gggtaggact aatgccttct gataccggcg aaccgggagg caggaaagtg
    50761 ggccagagca tgacccatta tattattgcc ggtggccctt tcgatatggc ctgtgatgaa
    50821 ctgctgacag gccatttccg gctttcctgg atggacaggt ttccgcctta ccagcctaag
    50881 cctggcgctg tgctaagccc tacaggaaaa ggctatattg acgacgagga agatgatagc
    50941 gaacacgaac aggaggtgga ggaagggcgc gacccggttg aactcgacga cgagatcata
    51001 gaggccatgc gatttgtaac cccgccgcct gaagcgccgg tgaacaaaac aaaccgggaa
    51061 aagtacagct gcccggtgtg tcatatcaat ctctggggta aaccggggat agtggtttac
    51121 tgtggtggcg agcactgtaa taaagccgcg ttagtagtct taaaataaag tcctttcgga
    51181 ctttattttt tttccatttc cgaggtcgtg atgttattaa tgctgtactt cgcggcttct
    51241 tttaaaacag tttcagcaag gcttgctggt atccagacct gaactaattt taatggttcg
    51301 ccgttctcgg ctttaagagt ggtgttctgg tacaaatccc agattcgctt aacggtgctg
    51361 gaaatgtttt gcttggaacg gcctactcgc gtggctacgt ctgatgattt ctcacctttg
    51421 acaagcacgg aatagccaat atctgttgtg atgtgtgcaa aggaagccat ttgcggcagc
    51481 agctgtttcc attctgtttc tgaaattctg tttttctgag ccatctgtgg cgcctccgta
    51541 gttttggtta cagaaaggat atactcagaa taaactgggg tcaatacaag tacgattttt
    51601 ataaacttta ttttatttga gggtgaggcc cggtgcggca gcagcgcggg cctcgatggt
    51661 gccgcgaagg tgctggcgcc atgcttggat taaaacatga accgtgaaga actgcgaaac
    51721 ttgttttcgc ggttctgagg ggttgaccga gccgcgaagc ggcgctggta agcgatgata
    51781 tgcacatatc cacaggcata tttttaaaag gtattttata gattttttat ctttttaaag
    51841 tcttttagag ctatataact cattgattta aaatcataaa taagtgttat ctctgggaat
    51901 ccgcccacct tgttatggga attggcccac ctatctatgg gaaacacccc accttactat
    51961 gggaattagc ccaccttgtt atg
//
