LOCUS       NC_022610              27326 bp    DNA     circular CON 07-DEC-2023
DEFINITION  Staphylococcus aureus subsp. aureus Z172 plasmid pZ172_1, complete
            sequence.
ACCESSION   NC_022610
VERSION     NC_022610.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02370325
            Assembly: GCF_000485885.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus subsp. aureus Z172
  ORGANISM  Staphylococcus aureus subsp. aureus Z172
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27326)
  AUTHORS   Chen,F.J., Lauderdale,T.L., Wang,L.S. and Huang,I.W.
  TITLE     Complete Genome Sequence of Staphylococcus aureus Z172, a
            Vancomycin-Intermediate and Daptomycin-Nonsusceptible
            Methicillin-Resistant Strain Isolated in Taiwan
  JOURNAL   Genome Announc 1 (6), e01011-13 (2013)
   PUBMED   24309740
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27326)
  AUTHORS   Chen,F.-J. and Lauderdale,T.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2013) National Institute of Infectious Diseases
            and Vaccinology, National Health Research Institutes, 35 Keyan Road,
            Zhunan 35053, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 7.0
            Reference-guided Assembly         :: NC_017352.1
            Genome Coverage                   :: 899x; 77x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/07/2023 08:13:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 2,987
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 59 of 104
            Pseudo Genes (incomplete)         :: 40 of 104
            Pseudo Genes (internal stop)      :: 21 of 104
            Pseudo Genes (multiple problems)  :: 15 of 104
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP006839.1.
            Bacteria and source DNA available from Tsai-Ling Lauderdale
            (Lauderdale@nhri.org.tw), National Institute of Infectious Diseases
            and Vaccinology, National Health Research Institutes, Taiwan.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27326
                     /organism="Staphylococcus aureus subsp. aureus Z172"
                     /mol_type="genomic DNA"
                     /strain="Z172"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="aureus"
                     /db_xref="taxon:1406863"
                     /plasmid="pZ172_1"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.99574716 N 121.5922526 E"
                     /collection_date="2010"
                     /collected_by="Tsai-Ling Lauderdale"
     gene            93..653
                     /locus_tag="SAZ172_RS15470"
                     /old_locus_tag="SAZ172_p101"
     CDS             93..653
                     /locus_tag="SAZ172_RS15470"
                     /old_locus_tag="SAZ172_p101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(969..1739)
                     /locus_tag="SAZ172_RS15475"
                     /old_locus_tag="SAZ172_p103"
     CDS             complement(969..1739)
                     /locus_tag="SAZ172_RS15475"
                     /old_locus_tag="SAZ172_p103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000848988.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKNLNISFKKENGINYINDNDCLK
                     IIEKITKKERTMQNKESIKKERFNENTAEFEKHIYNNSNGFESLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEERQLN
                     YSFDTATNDRQSINPQEATFTEEYQNSNQQQKKIQPIEAELNHKGITKAKKDDSSNEDV
                     LKRDDKLSEEIESGPEDREVETPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            2183..3127
                     /locus_tag="SAZ172_RS15480"
                     /old_locus_tag="SAZ172_p104"
     CDS             2183..3127
                     /locus_tag="SAZ172_RS15480"
                     /old_locus_tag="SAZ172_p104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001132442.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDRNNNIYFIFSNKHLCEYLGYGEQKIIKLKKELVNFNLLTQERVGLN
                     KPNRLYLLKPNYDIEASLTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTELNNTN
                     YIENEDNDTYDMNDIISNTLINNNHHSNHTNHQKTEFNNDALKFQVLEELPQQLQDYLS
                     KFEIREIRIIKSVLLKGKKSFNTSHDTYYRLEDVEFEIVSVLKRFKAMLLQKNETVEAM
                     QGYLMQSIKAELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            3242..3445
                     /locus_tag="SAZ172_RS16925"
                     /old_locus_tag="SAZ172_p105"
     CDS             3242..3445
                     /locus_tag="SAZ172_RS16925"
                     /old_locus_tag="SAZ172_p105"
                     /inference="COORDINATES: protein motif:HMM:NF013603.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_001796115.1"
                     /translation="MYRKRMLSYGGLLKEKHKILNLDDAEDGNLINTSDEDKTTDEEEK
                     AHSITAIWNFEKQNYYLKNLRS"
                     /name="protein rep"
     gene            3450..3596
                     /locus_tag="SAZ172_RS16800"
                     /old_locus_tag="SAZ172_p106"
     CDS             3450..3596
                     /locus_tag="SAZ172_RS16800"
                     /old_locus_tag="SAZ172_p106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001092935.1"
                     /translation="MNTKILTGMTGSSLERKINNFINDNQIEVIDIKFSSSVFYFGVMI
                     IYK"
                     /name="hypothetical protein"
     gene            4177..4365
                     /locus_tag="SAZ172_RS15490"
                     /old_locus_tag="SAZ172_p107"
     CDS             4177..4365
                     /locus_tag="SAZ172_RS15490"
                     /old_locus_tag="SAZ172_p107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001030803.1"
                     /translation="MNKDTMLDKGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            4749..5365
                     /gene="cadD"
                     /locus_tag="SAZ172_RS15495"
                     /pseudo=""
     CDS             4749..5365
                     /gene="cadD"
                     /locus_tag="SAZ172_RS15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            5384..5731
                     /locus_tag="SAZ172_RS15500"
                     /old_locus_tag="SAZ172_p111"
     CDS             5384..5731
                     /locus_tag="SAZ172_RS15500"
                     /old_locus_tag="SAZ172_p111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119692.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDGI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5924..6064
                     /locus_tag="SAZ172_RS15505"
                     /old_locus_tag="SAZ172_p112"
     CDS             5924..6064
                     /locus_tag="SAZ172_RS15505"
                     /old_locus_tag="SAZ172_p112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199886.1"
                     /translation="MQYNTTRSITENQDNKTLKDMTKSGKQRPWREKKIDNVRFCCKVK
                     K"
                     /name="hypothetical protein"
     gene            complement(6099..>6200)
                     /locus_tag="SAZ172_RS16660"
                     /pseudo=""
     CDS             complement(6099..>6200)
                     /locus_tag="SAZ172_RS16660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(7083..7994)
                     /locus_tag="SAZ172_RS15510"
                     /old_locus_tag="SAZ172_p1113"
     CDS             complement(7083..7994)
                     /locus_tag="SAZ172_RS15510"
                     /old_locus_tag="SAZ172_p1113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_078065941.1"
                     /translation="MSNFATEPNVSYADILEILKIKKAYNVKQCGNVLEFKPTDEGYLK
                     LHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLSTKNAIDGDTL
                     EQSLKHLTKAFDRLSRYKKVKQNLVGFMRSTEVTVNKNDGSYNQHMHVLLCVENAYFRK
                     KENYITQEEWVNLWQKALQVDYRPVANIKAIKPNQKGDKDIESAIKETSKYSVKSSDFL
                     TDNDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGNLINTSDEDKITDE
                     EAKAHSITAIWNFEKQNYYLRH"
                     /name="protein rep"
     gene            8031..8705
                     /locus_tag="SAZ172_RS15515"
                     /old_locus_tag="SAZ172_p114"
     CDS             8031..8705
                     /locus_tag="SAZ172_RS15515"
                     /old_locus_tag="SAZ172_p114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISSau6 family transposase"
                     /protein_id="WP_001105943.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITNQAPSTKVAMSKVIKDFKLTPNCHCNSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRFLQIYGFSPCRVISIML
                     AS"
                     /name="IS6-like element ISSau6 family transposase"
     gene            <8765..8869
                     /locus_tag="SAZ172_RS16980"
                     /pseudo=""
     CDS             <8765..8869
                     /locus_tag="SAZ172_RS16980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109600.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            10369..10977
                     /locus_tag="SAZ172_RS15520"
                     /old_locus_tag="SAZ172_p116"
     CDS             10369..10977
                     /locus_tag="SAZ172_RS15520"
                     /old_locus_tag="SAZ172_p116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017432088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000793183.1"
                     /translation="MKNLKSFFIKNTLVLTSTALLFSSFEPVVHAAENKEVVKTVENDN
                     VEFNELLEGQEYIWEVLSRDDEGFKMFLDEQRAFNPNFDNDVLLAKQEGALNSSVFANN
                     SMTLNSNKPTPRGPIGATLKAIKALSPSLRHGGTAISWIIKPLSRKHAVLVKKYSRKMS
                     NAIDRLDKSTKSAVENAFVKAGIPRSDAKTLTYIVFLVI"
                     /name="hypothetical protein"
     gene            11455..11550
                     /locus_tag="SAZ172_RS16665"
     CDS             11455..11550
                     /locus_tag="SAZ172_RS16665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000889979.1"
                     /translation="MLEILVHITTTVISGCIVALFTHWLRNRNDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            11787..12461
                     /locus_tag="SAZ172_RS15525"
                     /old_locus_tag="SAZ172_p117"
     CDS             11787..12461
                     /locus_tag="SAZ172_RS15525"
                     /old_locus_tag="SAZ172_p117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105988.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            12580..13095
                     /locus_tag="SAZ172_RS15530"
                     /old_locus_tag="SAZ172_p118"
     CDS             12580..13095
                     /locus_tag="SAZ172_RS15530"
                     /old_locus_tag="SAZ172_p118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000377078.1"
                     /translation="MDSHLNHILSYWQGPPLEGAKTIISKYGYPQEATMSRLIWYNSGP
                     WKRTIVYKDPVPHNFPTPHLDFLKQTIDYKVPVHLYDAIAAFDGSVYLDRTTGEASAKC
                     HEEAMNFLSLNLLNDIVTGKRDVQGAKAFYAQTAEQFTKYHITSPYTEGFLFPMQYNTA
                     DLGVTYFK"
                     /name="hypothetical protein"
     gene            complement(13290..13940)
                     /gene="merB"
                     /locus_tag="SAZ172_RS15535"
                     /old_locus_tag="SAZ172_p119"
     ARG             complement(13294..13940)
                     /name="merB"
                     /gene="merB"
                     /gene_name="organomercurial lyase MerB"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14022..15665)
                     /gene="merA"
                     /locus_tag="SAZ172_RS15540"
                     /old_locus_tag="SAZ172_p120"
     ARG             complement(14026..15665)
                     /name="merA"
                     /gene="merA"
                     /gene_name="mercury(II) reductase"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15723..16109)
                     /gene="merT"
                     /locus_tag="SAZ172_RS15545"
     ARG             complement(15727..16109)
                     /name="merT"
                     /gene="merT"
                     /gene_name="mercuric transport protein MerT"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16197..16877)
                     /locus_tag="SAZ172_RS15550"
                     /old_locus_tag="SAZ172_p121"
     CDS             complement(16197..16877)
                     /locus_tag="SAZ172_RS15550"
                     /old_locus_tag="SAZ172_p121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010351.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="WP_000010352.1"
                     /translation="MSFSFLFILTAGMVAAFNPCGIALLPSYISYLIGGETKDHSFRYA
                     IFKGLGLGGAMTTGFLTIFVLAGLLIGGLGSALTGIFPILSLVMGILIALLGLGMLFGK
                     HLPIKIGSFQVKPGKWSIYFYGIAYAVTSLGCTLPAFMLVVSASLNDNSVTAVIIKFII
                     YSLGMGIVVTAITMVSLISRQLVQKFLHNYMGSIQKIAAVVIFLSVLYMAYYWYFGSGG
                     ICTF"
                     /name="cytochrome c biogenesis protein CcdA"
     gene            complement(16874..17359)
                     /locus_tag="SAZ172_RS15555"
                     /old_locus_tag="SAZ172_p122"
     CDS             complement(16874..17359)
                     /locus_tag="SAZ172_RS15555"
                     /old_locus_tag="SAZ172_p122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746200.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_000746202.1"
                     /translation="MKKRISFTAIMTVLLIGLTACGAESDTANESKVQDIQGNPVSLPN
                     EKPTLIYFMATWCPSCIYNEEIFKEMHQLNPNDVQLITVSLDPNTDTKESLAKFKQDYG
                     GDWPHVLKNGKEIADTYGVKQLEEIVLVNSENEVFYRSVRPSFDDLKEALTQIGVEL"
                     /name="TlpA disulfide reductase family protein"
     gene            complement(17376..17783)
                     /gene="merR"
                     /locus_tag="SAZ172_RS15560"
                     /old_locus_tag="SAZ172_p123"
     CDS             complement(17376..17783)
                     /gene="merR"
                     /locus_tag="SAZ172_RS15560"
                     /old_locus_tag="SAZ172_p123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator MerR"
                     /protein_id="WP_000525462.1"
                     /translation="MGMKISELAKACDVNKETVRYYERKGLIAGPPRNESGYRIYSEET
                     ADRVRFIKRMKELDFSLKEIHLLFGVVDQDGERCKDMYAFTVQKTKEIERKVQGLLRIQ
                     RLLEELKEKCPDEKAMYTCPIIETLMGGPDK"
                     /name="merR"
     gene            complement(18083..>18826)
                     /locus_tag="SAZ172_RS15565"
                     /old_locus_tag="SAZ172_p124"
                     /pseudo=""
     CDS             complement(18083..>18826)
                     /locus_tag="SAZ172_RS15565"
                     /old_locus_tag="SAZ172_p124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163428.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /name="FAD-dependent oxidoreductase"
     gene            18882..19556
                     /locus_tag="SAZ172_RS15570"
                     /old_locus_tag="SAZ172_p125"
     CDS             18882..19556
                     /locus_tag="SAZ172_RS15570"
                     /old_locus_tag="SAZ172_p125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105968.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWHIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(19791..21974)
                     /gene="cadA"
                     /locus_tag="SAZ172_RS15575"
                     /old_locus_tag="SAZ172_p126"
     CDS             complement(19791..21974)
                     /gene="cadA"
                     /locus_tag="SAZ172_RS15575"
                     /old_locus_tag="SAZ172_p126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase CadA"
                     /protein_id="WP_000003264.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAKV
                     NFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFYKK
                     HSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDFDMK
                     TLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEALVMR
                     NGQEIMIHVDDIAVGDIMIVKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEV
                     FAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYTPIIMVI
                     AALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKG
                     GVYLEELGAIKAIAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALEYRSQHPLA
                     SAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKELNVSDFSLGF
                     ENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSKNVIQKLHQLGIKQTIMLTGDN
                     QGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVNDAPALAASTVGI
                     AMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVI
                     PGWLTLWIAILSDMGATILVALNSLRLMRVKDK"
                     /name="cadA"
     gene            complement(21967..22335)
                     /gene="cadC"
                     /locus_tag="SAZ172_RS15580"
                     /old_locus_tag="SAZ172_p127"
     ARG             complement(21971..22335)
                     /name="cadC"
                     /gene="cadC"
                     /gene_name="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM/LEAD/ZINC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22707..23285
                     /locus_tag="SAZ172_RS15585"
                     /old_locus_tag="SAZ172_p128"
     CDS             22707..23285
                     /locus_tag="SAZ172_RS15585"
                     /old_locus_tag="SAZ172_p128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690625.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNRLNNQENKDK"
                     /name="recombinase family protein"
     gene            23411..24019
                     /locus_tag="SAZ172_RS15590"
                     /old_locus_tag="SAZ172_p129"
     CDS             23411..24019
                     /locus_tag="SAZ172_RS15590"
                     /old_locus_tag="SAZ172_p129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            24265..24603
                     /locus_tag="SAZ172_RS15595"
                     /old_locus_tag="SAZ172_p130"
     CDS             24265..24603
                     /locus_tag="SAZ172_RS15595"
                     /old_locus_tag="SAZ172_p130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            24608..24793
                     /locus_tag="SAZ172_RS15600"
                     /old_locus_tag="SAZ172_p131"
     CDS             24608..24793
                     /locus_tag="SAZ172_RS15600"
                     /old_locus_tag="SAZ172_p131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(24926..25492)
                     /gene="qacR"
                     /locus_tag="SAZ172_RS15605"
                     /old_locus_tag="SAZ172_p132"
     ARG             complement(24930..25492)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            25670..27214
                     /gene="qac"
                     /locus_tag="SAZ172_RS15610"
                     /old_locus_tag="SAZ172_p133"
     CDS             25670..27214
                     /gene="qac"
                     /locus_tag="SAZ172_RS15610"
                     /old_locus_tag="SAZ172_p133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_000622774.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSIMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     ARG             25671..27211
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.81"
                     /coverage="100.0"
     Typing          3674..3776
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="83.81"
                     /coverage="100.0"
                     /evalue="1.39e-18"
     Typing          complement(6881..7028)
                     /name="MOBV"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2184..3127
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.577"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3258..3435
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.179"
                     /coverage="95.0"
                     /evalue="3.73e-65"
     Typing          complement(7084..7971)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.288"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 attataaaag acaatttctt aaattaataa tatgatatac ctatatctaa taatttatta
       61 gtattaataa accttgaaag gatgattaac tgatgaatag agcagatatt tttaaaatat
      121 ttgatgtaga acttaatata actatatttt taggagcact agtagcaact ttcatctatt
      181 ttataagtta catgaacaat gtaaatgaat taattacatt atgcttaaca ttagcttttc
      241 ctgcatattt attaaaaatt agcagatcgt tcgaggttat tttattagag gaaaaaataa
      301 aaaatagtaa aatcaaaatc tgtgacaaag atagaattga acgagagata ctggtgaaaa
      361 agaacctaat agatgaacta ttgtttccta atagagttat taaaaaatat acactgacaa
      421 ttttaattta cagtataggt attattattc ttttactact ttgtaatatg ttaagttatg
      481 gaattggtga aaatgtcaat tttatctgga gattactagc ttgttatgta acgagtgtca
      541 cagtgattat agttgccttg attataatga taatgatatt tgatcttata attggattac
      601 tattaaattt tcaaatattt ttaaaaaata aaaagtatga tgacttttta taattattcg
      661 atttatataa tgaaaaatta aatgattaaa catagaaacc tcaaaacaaa ccatatttaa
      721 tagagtttat ggcgccttat acaaataaag gctatgctgt taaagaatta tgtagctatc
      781 ttcagattaa tatggatgat gtttatacta ttggcgatag aaaattgatt tacctatgtt
      841 taatacccta gataattctt ctgataattt agtttttgtt agagtttaac ataactgatg
      901 attaccagaa gttctcacta tataaaaggc actaaaagtt ataaactttt agtgcctaat
      961 taattatttt agctaccaaa caaacgactc caaaacccct ttttaggtgt ttctacttcc
     1021 ctgtcctcag gtccactctc tatttcttca gatagtttat catctctctt taatacgtct
     1081 tcgtttgaac tgtcatcctt tttcgcttta gttatgccct tatgatttaa ttctgcttct
     1141 attggttgta ttttcttttg ttgttggttg ctattttgat attcttcagt aaaagttgct
     1201 tcttgcggat taatgctttg tctatcatta gtcgctgtat caaaagagta attaagctgt
     1261 ctttcttctt ctaattggtt ttctagtttt tgaatctttt tattactttc taaagctaat
     1321 atttgttgat tctccaacag tttatttaat gtattaacat tgctattttg ttgatctagt
     1381 tgtttagtta aattctcaat atatttttcg tcatttttag ctctagtttc aaagatttct
     1441 atttgctttt ctaattcatt tacttttgtt tttaatgact caaaaccatt tgaattattg
     1501 tatatatgct tttcaaactc tgcagtattt tcattaaatc tttctttttt tattgattct
     1561 ttattttgca ttgtcctttc tttcttagtg atcttttcta taatttttaa acaatcatta
     1621 tcattaatat aattaattcc attttctttt ttaaaagata tatttaagtt tttagcatta
     1681 ttaacaatag tttgtttagt tacattcaat tcatcagcaa ccattttaat agttttcata
     1741 acattcatcc ttaggtacat aaattggtac ctaaatttta ccacctaaca aatatttttt
     1801 catctttcga catctaaatt tactacctat ttcactactt tagtacctaa ttagccgtta
     1861 aaaccttcta taggtgacta attaggtact aaagtggtga atttttatca ttttaaagtt
     1921 acaatgttct ttcaactaaa cttaaaaagc tttatataca atcttaaaag tgttaatatt
     1981 actttgtgaa tattaaaaga gtcgatacta ttggcgtagc atcgactctc ggtaataaaa
     2041 cgattcgcat tcgtctgttt atataatttt ttgatacttg tattatatat atctaatcat
     2101 ataagtgcaa gtacaaaaca tataacctac gtaaaaattg ttttattacc tctatccaaa
     2161 aagtggaaat gaggttttta ttatgcccaa ttttgagaaa tacaatttat cacaagtaaa
     2221 aactgaaaga ttttaccaac ttcctaaata tttgttcgaa gatgcatatt ttaagaaaat
     2281 gtcagcagaa gccaaaatta tgtatgcatt attaaaagat cgtttcgaat tatccatcca
     2341 aaatgaatgg gtagatagaa ataataacat ttactttatt ttcagtaata aacatttgtg
     2401 cgagtactta ggttatggag aacaaaaaat cataaaattg aaaaaagagt tagtaaattt
     2461 taatttatta actcaagagc gtgttggcct taataaacca aatagattat atttattaaa
     2521 accaaattat gatattgaag caagtcttac caaggaactt ccaaattcac agttccagaa
     2581 caatgaattt ggaagttcta gaactgtgaa tttaagtggt caagaacttc caaattcaca
     2641 gtctaatgat actgagttaa ataatactaa ttatatagaa aatgaggata atgatacgta
     2701 tgatatgaat gatattatat ctaatacttt aataaataat aatcatcatt cgaatcatac
     2761 aaatcatcaa aaaactgaat ttaataatga cgcccttaag ttccaagtac tcgaagaatt
     2821 gccacaacaa cttcaagact atttaagtaa atttgaaatt agagaaattc ggattattaa
     2881 aagcgtatta ctcaaaggga aaaagtcatt taatacttca catgatactt attatcgttt
     2941 agaagatgtt gagtttgaaa ttgtaagtgt attgaaacgt tttaaagcga tgttgctaca
     3001 aaagaatgaa accgttgaag ctatgcaagg ttatttaatg caatccatta aagctgaact
     3061 tgaagaaaca catgcccttt atatgcgccg taaaaacatg aaacaatata atatctttaa
     3121 tcaataattc aaatgatttt ataacaatca aagagacatc aaaatattcc gttaaatcat
     3181 ctgacttttt aactgatgac gacgaaaaaa atcaagaaat tttaagtgat ctagaaaagg
     3241 tttgtatcga aaacgtatgt taagttatgg tggattactt aaagaaaagc ataaaatttt
     3301 aaacttagac gatgccgaag atggtaattt gattaataca agtgatgaag ataaaacgac
     3361 agacgaagaa gaaaaagcac attcgattac agcaatttgg aatttcgaaa agcaaaatta
     3421 ttatttaaaa aatttaagga gttaaaaata tgaacactaa aattttaact ggaatgactg
     3481 gaagttcttt agaacgaaaa atcaataatt ttattaatga taaccaaatc gaagtcattg
     3541 atattaagtt ttcaagttct gtattttatt ttggggtaat gattatttat aaataattaa
     3601 agagtttaag acattagtga tgactgatgt ctttttttac tgttttttta taaaaaagta
     3661 ctggcttatt tttgtgacaa atgcaatata ttgtgtcaca aaagtgtgac acttaagctt
     3721 tttatgaccc cacataaaaa tattgttgaa gctttgaatt gtctggcttt gccagatacc
     3781 ccatgtatac atggggtcaa atttccctta tgctcttacg gagttacgga gttcttagag
     3841 aaaaattaaa aattctcgat ttttgataaa aagcgccctg caggaattta gaaaaacatg
     3901 ggggaagttt taaaggattt tatgctaatt tttaatttgc atgtaaatgg gcagtgttta
     3961 aaaaaatagt cattggtttt atttaaaatt ttgtttttga aaatagcata tatgtatttg
     4021 gttcatattt gcgttttaag agattatgta ggttttagat agaaaactat atgatttacc
     4081 cctaaatctt taaaataccc ccttaaaatt caaaataaag gtatttataa tttgagtaag
     4141 tcttgtgata aagtttttta aaaaggagtt tttattttga ataaagacac aatgttagat
     4201 aaaggttacg ttatagcaac tattttaaat gttttctttt tacttggatt aatttttata
     4261 tctcatttgg aaaatttata tatattaatt ccgtatgtta ttttgatggg aataaatgct
     4321 atttatttgg ttgttaaagt tatgaatttc aaaaagaata attagaatat ttgaggggat
     4381 tttgaaacga gtttcttctt gttttcacac tattttttat tcctattggt gttgttgctt
     4441 actttttgtt tttctatgaa gatgatgatt ttgacgagat ggaagaaaaa tatgattatc
     4501 atgaagataa aaaaatagac gacgcattta tgccgagaaa atttattgat gttgagaaga
     4561 acccttaact aaacttgaag acgaatgtcg gcatagcgtg agctattaag ccgacgattc
     4621 gacaagttta gggattgtta agggttccga ggctcaacgt caataaagca attggaataa
     4681 agcacctatg attatttaaa aatattagtt ataatacatt caaaaatatt tttgaatgag
     4741 gtgtatgtat gattcaaacg gttgtcactg ctgctattct ttatattgct acagcatttg
     4801 atttattagt aattttatta atattttttg ctagagcaaa gactaaaaaa gaatatagag
     4861 atatttatat tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4921 cttttgtatt aaattatgtt tcagagaagt ggatattagg tttattgggt ttaataccaa
     4981 tttatcttgg aattaaagtg gctatttatg tgattgtgaa ggagaaaaga gagctaaaaa
     5041 agaactgaat gaaaaaggat tgtctaaatt agttggtacg gttgcaattg ttacgatagc
     5101 aagttgtggc gccgataata ttggtttatt tgttccgtat tttgtgacat taagtgttac
     5161 taatttatta cttactctgt ttgtcttttt aattttaatt ttcttcttgg tgtttactgc
     5221 acaaaaatta gctaatatcc caggaattgg agaaattgtt gagaaattta gtcgttggat
     5281 tatggctatt atttatatag ctttaggttt atttattatt attgaaaatg acactattca
     5341 aacaatttta ggatttatat tttaatttag ggtgtgattt tatatgagtt atgaaaatac
     5401 ttgtgatgtg atctgtgtac atgaggataa agttaacaat gctttaagtt ttttagaaga
     5461 tgataaatct aagaaattac ttaacatttt agaaaaaatt tgtgatgaga agaaattgaa
     5521 aatcatatta tctttgatta aagaagatga gttgtgtgtt tgtgatattt ctttgatatt
     5581 gaaaatgagt gttgcttcaa cttcacatca tttaaggctt ttatataaaa atgaggtact
     5641 tgatttttat aaagatggaa agatggcata ttattttatt aaagacgatg gaataagaga
     5701 gtttttctct aaaaatcatg agggtttttg aaacgagttg aaaacgagtt tcttcttgtc
     5761 ttgatactat atagaaataa cgttcttttc taaaatcctt ttgaagcgtt gatatgacgg
     5821 cgtttcatac tgttttgctt ggggaaaata aaatttgaca ataaaaaacc ccagttatat
     5881 tattaaggtg tcgaatctta aataatactg ggggtctttt tatatgcaat ataatactac
     5941 tagaagtata accgaaaatc aagataataa aacgttaaaa gatatgacga aaagtgggaa
     6001 acaacgccca tggagagaaa agaaaataga taatgtaagg ttctgttgca aagttaaaaa
     6061 ataagtgtct aaccttatgt ttaaagtaat actttgtatt aactagctag catgatgcta
     6121 attacacggc atggcgaaaa cccgtagatc tgaagagatc tgcggttctt tttatatagt
     6181 ccataaatac attcaatgcc tgtgtatttt attccaattg ctttattgtc gttgagcctc
     6241 ggaaccctta acaatcccaa aacttgtcga atggtcggct taatagctca cgctatgccg
     6301 acattcgtct gcaagtttag ttaagggttc ttctcaacat caataaattt tctcggcata
     6361 aatgcgtcgt ctaacttttt ttataatgtt tatcaaacca cgatgaaaaa aatataaaaa
     6421 agactgtata aagaataaac caagtatcta aatgattttg attcatttgc ttataaataa
     6481 aaaacaataa aaaaatacca agaataattt gtaaaataaa taaagacctc ttcaaaaaac
     6541 cactcctttt aaaaaacttt atctcaggac ttattcaaat tataaacacc tttattttga
     6601 attttaagag ggtattttaa agatttagag gtaaatctta tagtcttcta cttaaaaatc
     6661 tatacaagct cttaaaacgc aaatatgagc caaataaata tattctgatt ttataatcaa
     6721 aaatttcagc aaaaccagtg actaattttt taacactgcc catttaaatg caaattaaaa
     6781 atgagcataa aatcttttaa aacttcccca tgtttttcta aattcctgca gggcgctttt
     6841 tatcaaaaat cgagaatttt taatttttct ctaagaactc cgtaagagca taaggagaat
     6901 ttgctatcat tcaaaaatga taggtctggc aaagccagac attccaaggg ttttaagtaa
     6961 ttttaaagtg atatcataaa aagctgtagt gtcacacttt tgtgacacta catacagcat
     7021 ttgtcacaaa aataagacag tactttttta caaaaaatca ataaaaaaga catcagtcat
     7081 cactaatgtc ttaaataata attttgtttt tcaaaattcc aaattgccgt aattgaatgt
     7141 gcttttgctt cttcatctgt tattttatct tcatcacttg tattaattaa attaccatct
     7201 tcagcatcgt ctaagtttaa aattttatgc ttttgtttaa gcaatccacc ataacttaac
     7261 atacgttttc gatataaacc tttttctaaa tcacttacaa tttcttgatt tttttcgtca
     7321 ttgtcagtta aaaaatcaga tgacttaacc gaatattttg atgtctcttt gattgccgat
     7381 tcaatatctt tatcgccttt ttgattaggt ttaattgctt taatatttgc aacaggtcga
     7441 taatcaactt gtaatgcttt ttgccataaa ttaacccatt cttcttgagt tatataattc
     7501 tctttttttc taaaatatgc attttcaaca cataacaaaa cgtgcatatg ctgattataa
     7561 ctaccatcat ttttattaac ggtaacttct gttgaacgca taaatccaac aagattttgt
     7621 ttaacctttt tatatctact caacctatca aatgctttag ttagatgctt caaactttgt
     7681 tctaaagtat ctccatctat cgcatttttg gttgaaagtg ttaaaaacaa ccaacgtgct
     7741 tttggctttt ccttaattac ttcttcaatc actttttgag cttgataact atttttcata
     7801 gcacgcctcc aattacaaac tggacatagc tttgatttac aaaaccacgt cttatgtaat
     7861 ttcaaataac cttcatcggt cggcttgaat tctaagacgt taccacattg ttttacgtta
     7921 taagcctttt ttatttttaa aatttcaagt atatctgcat agcttacatt aggttctgtt
     7981 gcaaagttag aaatatagta taatagtcaa caaaaaatga ggtgcagagg atgaattatt
     8041 tcagatataa gcaatttgac aaagatgtca ttactgtagc cgttggctac tatctaagat
     8101 atgcattaag ttatcgtgat atatctgaaa tattgagaga acgaggcatc tatgttcatc
     8161 attcaacaat ttatcgatgg gtacaggaat atgctcctat tttgtatcaa atttggaaga
     8221 aaaaaaataa gcaagcttat tataaatggc atatagatga gacgtatatc aaaattaaag
     8281 ggcaatggaa ttatttatat cgcgctattg atgcagatgg ccatacacta gatatttcgt
     8341 tacgtaagaa acgagataat cactcagcat atacgtttat taaacgtctt attaaacaat
     8401 ttggcaaacc tcaaatgata attacaaacc aagccccttc aacgaaggtg gcaatgtcca
     8461 aagtgattaa agattttaaa cttaccccca actgtcattg taactctaaa tatttaaata
     8521 atctcattga acaagatcat cgtcatatca aagtaaggaa aataagttat caaagtatca
     8581 atacggcaaa gaatacgatc aaaggcattg aatgtattta tggactatat aaaaagaacc
     8641 gcagatttct tcagatctac gggttttcgc catgccgtgt aattagcatc atgctagcta
     8701 gttaatacga agtattattt taaacataag gttagacact tattttttaa ctttgcaaca
     8761 gaaccaagaa atcgatccaa ctgaatacct ttaccaaatt tattatattt ggaatcagaa
     8821 agagtacctg gcaagtgaac ttcacgaact taccgaagaa gaacaataaa aaaatataaa
     8881 aatattttga gagttgacca cccacatttg tagtttacgg agaacgtggg tggtcaactc
     8941 tcaaaattta tttcttaaaa atttatttgt tgttctgatg agcgatgaac gactaaaaaa
     9001 gtataatgct attttctatc attacacttt ttttatacgc ttattatact ttcgttatac
     9061 tctttttgtc gctacacgaa ctatgtgatc aaacggcacg tttgcccatt taaaatgcaa
     9121 attcggaacg atttattgct aatttttaaa tttgcatgta aatgggcagt acgtaaaaat
     9181 cgcccgtcct ggtgtcgaaa aaacgaacag aaaaaataaa attaaaatat agtaatcttt
     9241 ttatttttta caggtaggtt tccccataat ttagtactgc atcagaaatt tatctgtact
     9301 tagaaatgac gacgtatttt ttctatacgt ttatgacatt tattctacat tgatccaaat
     9361 cataaaaatg tgtttaaaat gtcctaaaaa ggttttaaaa ggacgatttt tttatattac
     9421 gtatttttgt actcaaaatt agagaatgct ctaaatgacc tcttaaaacg caaaaaaaaa
     9481 tatatatcaa aaagacatgt atttttaaaa aaattgatgt gtatgatgca tgtcttttgt
     9541 gtatgtttta tatacataaa gtatatgtat acgtaacctg tatgtataca taacgttatg
     9601 gtttttatac atatgagtta aaaaagtgat gtcacttttt ttctaggaaa aataactcgg
     9661 cactgccgag ttcaccacgt tatgggtctg ccaaaatata aaagtggtgg cactttccct
     9721 tatgctcatg actttatgta taaaagttag aggtactttt atgccgagaa aactttttga
     9781 gagattaatt tttttatttt tttatttttt acttttattt tcttcaaata ttttgtaaat
     9841 ctctttatga gtaaataaaa gatagaagca taaagaataa atgaaaattt gaaaatataa
     9901 gtttatatga atgttgtaga aaatcttcaa aattattaag tttaatacga tcatattagc
     9961 agttataaag aatatgaata agataatatt attaaatttc tttttgtatt ttatatgtaa
    10021 aaatattata aaaagttcaa gaaaaataaa tattagataa gttactataa agaataatgc
    10081 aatatagcca atgttataaa acatattatt tgaataccaa tttattgtta ttaaagaact
    10141 tatatttaaa ttatctgcta atgattggaa acctattatg ctaaaaaatg gtattgagaa
    10201 tactaatacg gatataggta tgattattat tccgagtaag aacgttacaa ttataaagtt
    10261 caataagtac tctttgttta cttttttcat aataatttaa ttccttttat gtatataata
    10321 tttaataata aaaaatttta acatttataa ttggaggata aaagtcatat gaagaattta
    10381 aaaagttttt ttattaaaaa tactttggta ctaacatcta ctgcattatt attttctagt
    10441 tttgaacctg tagttcatgc tgcagaaaat aaggaagttg ttaaaacagt agaaaatgat
    10501 aatgtagaat tcaatgaatt gttagaagga caagaatata tttgggaagt tttatctaga
    10561 gatgatgaag gatttaaaat gtttctagat gagcaaagag cttttaatcc taattttgat
    10621 aatgatgttt tactagcaaa acaagaaggt gctttaaatt cttcagtatt tgctaataat
    10681 tctatgactt taaactcaaa taagcctact cctagaggtc ctatcggtgc aactttaaaa
    10741 gctattaagg ctctatcacc ttctttgaga catggtggaa ctgctatatc ttggatcatt
    10801 aaaccattaa gtagaaaaca tgctgttcta gtaaaaaaat attcaagaaa gatgtctaat
    10861 gcaattgata ggttagataa gtctacgaaa tcagctgttg aaaatgcttt tgttaaagca
    10921 ggtataccaa gaagtgatgc gaaaacttta acttatattg tatttttagt tatttagata
    10981 ttgagctgac ttgccctaag attttataaa atcttagggc aagttttttt cttttttctt
    11041 atcttgataa agtagtattt tcaatttgtg attggggtga tgattttcta gatacagtta
    11101 aaattaataa tcatagataa tgagagaacc tacaattatc ataagttttc acctaaaaag
    11161 gatatattaa agttttacaa atctttaatg caccttttag agtgttttta aatctattct
    11221 ttaatagact ataatattca ctatttatta caccgttttt tctttagatt aatgaattta
    11281 ggtgatgatt ttgaactgcg tttcttcttt tgtcttgata ctataaaaaa cgaagttata
    11341 taacataaga cgacttatcg gaagtagata tgcttgtata ttcacagatg gtataataat
    11401 agagtcgcct atctctcagg cgtcaaattt agacgcagag aggaggtgtt attcatgcta
    11461 gaaattcttg ttcacatcac gaccacagtc atcagtggtt gtattgttgc gttatttacg
    11521 cattggctac gcaatcgcaa cgataaatag gcgactatag tcacacctaa aaaatcccct
    11581 cactacggca atagtgaggg gattggtgta ttcacgctag aattcttgtt aatcatatta
    11641 taacactggt tagtagagga atgcaaaaac ataagaaacg taagtgtaac tctataatta
    11701 gaattattaa ttttctttga tactataaaa gattctgttg caaagttgaa tttatagtat
    11761 aattttaaca aaaaggagtc ttctgtatga actatttcag atataaacaa tttaacaagg
    11821 atgttatcac tgtagccgtt ggctactatc taagatatgc attgagttat cgtgatatat
    11881 ctgaaatatt aagggaacgt ggtgtaaacg ttcatcattc aacggtctac cgttgggttc
    11941 aagaatatgc cccaattttg tatcaaattt ggaagaaaaa gcataaaaaa gcttattaca
    12001 aatggcgtat tgatgagacg tacatcaaaa taaaaggaaa atggagctat ttatatcgtg
    12061 ccattgatgc agagggacat acattagata tttggttgcg taagcaacga gataatcatt
    12121 cagcatatgc gtttatcaaa cgtctcatta aacaatttgg taaacctcaa aaggtaatta
    12181 cagatcaggc accttcaacg aaggtagcaa tggctaaagt aattaaagct tttaaactta
    12241 aacctgactg tcattgtaca tcgaaatatc tgaataacct cattgagcaa gatcaccgtc
    12301 atattaaagt aagaaagaca aggtatcaaa gtatcaatac agcaaagaat actttaaaag
    12361 gtattgaatg tatttacact ctatataaaa agaaccgcag gtctcttcag atctacggat
    12421 tttcgccatg ccacgaaatt agcatcatgc tagcaagtta agcgaacact gacatgataa
    12481 attagtggtt agctatattt ttttactttg caacagaacc cctaaaattc atttattggg
    12541 catacaatgc ttttaggcaa atgtttagga ggtatggcaa tggatagtca tttaaatcac
    12601 attttgtcct attggcaggg accaccgttg gaaggggcaa aaaccataat tagtaagtat
    12661 ggatatcccc aggaagcaac aatgagtcga ttaatttggt acaatagcgg gccatggaaa
    12721 cgcacgatag tatataagga tccagtccct cataacttcc ctacccctca ccttgatttc
    12781 cttaagcaga ccatcgatta taaagtgccc gtacacttat atgatgcgat tgccgctttt
    12841 gatggaagtg tctacttaga tcgaactaca ggtgaggcat cagcaaagtg tcatgaggaa
    12901 gcgatgaatt ttttatcttt aaacttgtta aatgacattg taactggcaa acgtgatgtt
    12961 caaggagcaa aagctttcta cgcccaaact gccgaacagt ttaccaaata tcatataaca
    13021 tctccttata cagaaggttt tctttttcca atgcaatata atacggcaga ccttggcgtt
    13081 acatatttta aataaggtgc cattttggca ccttatttac tcctatattc aagaatccac
    13141 tttctcgctt tattaactcc ccgatatagg cacaagcaat tgatcttttt atttatttgg
    13201 tttcccataa aattggtttc actagataga gcttcggtta caggacatca tcgtaaggcc
    13261 aagattgacg caggcgtaat tgcctaagat taaatgttac aacaggaccc attagtaggt
    13321 cctgactcct cataacgcgc tcccaaatgg cgacccagtt caaaggcatc ttcaacgggc
    13381 aaaacgctcg actcagggtg ttggttaagc cagtcttggg ctgcactcgg tgaactgaaa
    13441 aagtgaacgt cgttacagaa ggccgaccga accgaggcca tttcatctgg tgtaacaatc
    13501 gagacaacgg ctgttgaagg ctcgacgctt acaacgcggt ccggttccac cgtcaaccgg
    13561 acggacttac cggtgccgtg acaaggcgaa gcgatgtgga ccgtccggcc gatgagtgct
    13621 gggaacataa gtgtgtcaag ggcgcaccat gcatatagtt gcttcccatc aacctcgaag
    13681 cgatgggggg tagggaacag tgtgaggcca taaccgacga cacggccctg ctcatcaagt
    13741 tccacactag gtagagtctg taggacttgc ttaacttcct cgacgggctt cccggtctcc
    13801 gccgcgatgt cctcaacggg gactggatcg ccctccgcca gcatttttag caacggacgg
    13861 aataaccact ccatagagac ggcttcccct tgatcaaaag tttgatcaag ttgggctgag
    13921 aattctgaaa tatttttcat aagcttattc ctccttatat tttctccact tcattgtttt
    13981 aagtgcctcc tgcaacatag cattagaatc aaaaggaacc attagcctgc acaacaagat
    14041 aatttcgata cgtctttatc aaacgtcaag gctgcaagct ttaatccttc agccatcgtt
    14101 aaataaggcg caaagctatc cgtaaggtct tcaatggtca atccaaattg aaccgctaac
    14161 gttgccgcat aaatcacatc tccagcattt tcactcacaa tgtgcgctcc gatcaatttc
    14221 tgggtttggg cgttgactac aagtttatag acccctgttg tttcgtgatt gactaaggcc
    14281 cgcggtacag cgtccaacgg aaggaccgat gttttgacat cgtaaccttt ttcttttgcc
    14341 tgttgttcag tcaagccgac tgtggcgatc gatggattgg tgaaggttac gccgggaaca
    14401 aagcgaagat cgattttgcg tttcgctaga cccaacgcat tatttgccac aatcccgcct
    14461 tcataagctg caacataaac gaattgcgga ccgagggtca catcgcccgc ggcatatatt
    14521 cggttattcg acgtttgcaa atattcattg gtcagcactt cgcctttttt ccctgttttc
    14581 acacctgctg attcaaggtt taaagtctct gtgttcggct ttcttcctgt tgccacgagg
    14641 acttgatcgg cttcgatgac ttgttcttga ccgttcactt caatataaat gcttgtcgac
    14701 ttaccgtttt gctcaacctt ttgataagtg accccagtga tcaggttaag tccttgctca
    14761 gttaaggatt catcgatggc ttcggaaatt tcaggatcgt aggttttaaa cagacgctcg
    14821 cttctttgca tgagagtcac ttctgttccg aggttgtgaa acatttgacc taattccgct
    14881 gcgatatagc cagaaccgat cactgccaat cgttgtggaa cctcttttaa ttcgagtgcg
    14941 gatgtacttg ttaaataatc aacctcattc attcccggga tttccggaac agccggagaa
    15001 gcccccgttg cgattaaaaa gcttttagac gtgatgtttt gtccattcac ttgtatcgtc
    15061 ttatcgtcga taaacgaggc ctcgccacga atgagatcaa atccatattc ttcgatcaag
    15121 tctatatatt tttcttgacg catttgactg actaatccat ctttttgttc ggtcaattgg
    15181 gcaaggtccg cagcaccggt actcgtttga agtccggtaa acggattgtt ttgggcgaga
    15241 ccgtttattt caccggcacg aagcatggtt tttgacggta cacaaccgat gttaacgcag
    15301 gtccccccga cggttccccg ttctaccatg gccactttcg ccccgttttc attggccttg
    15361 atagctgcag aaaacgccgc accgccggaa ccaataatca gaagatcgta atcgccatcc
    15421 cgattgaaat ctacactgtt ttcagagggc tggctttctt cctctccggg ttgatagccg
    15481 gctgccgaaa tattttgctt agccttttcg atctgatcat cgctgagttc aaaaatggcc
    15541 tcaccgcgtc ggaaatcggc cgaaacatct ttagctccgg cttgttccaa tgcttcggtt
    15601 acatgttctt cacagcctgt gcatgtcatg ccttgaatgg gtattttata tgaattttga
    15661 gtcatttgaa tccctctttc tatttaaagt ttgatagaca gttctgtaca tttatctcat
    15721 atttatcttg tctcatgttt ccgatccacg ctctctggag gcgtacagca atccgtttta
    15781 ttttttgttt ttccattgcc ttcaggagaa ttgtatttgt tcttcaacaa cttgctgagg
    15841 atcagagcaa tcataacaat ggccaatgct gcaaaaatgc cggtcaacca ccaatttcct
    15901 gtcgcaccag caaagagggc accaatacct gtgctcccta atgcaacaag gagaatcggt
    15961 cctgcgcaac aaagtaaagg aaccaataaa ggaaccaata atattccgaa aaaggcccaa
    16021 acaccccagc ggttaccttt cgagcgattc tcatccatca ttctcaccac tctttctaaa
    16081 aaaaatttta ttctttggtt aaggtacata catggcctat agcctaactt gaaatttgtt
    16141 cgtttagctt ttttacatct ttcatctatt ttttgttaca cctgatcggt tggattttaa
    16201 aatgtacaaa tgccaccaga accgaaatac cagtaataag ccatgtacaa aacggagagg
    16261 aaaatcacaa cagctgctat tttttggata gaacccatat agttgtgcag aaacttctgt
    16321 accaattgtc gtgaaatcaa tgagaccatc gtgatcgctg tcaccacaat tcccatacca
    16381 agggagtaga tgatgaactt gatgatcacg gccgttacgc tattgtcatt cagcgatgca
    16441 gagaccacca acataaaggc tggcaaggta caaccaagtg atgtcacggc ataggctatt
    16501 ccgtaaaaat agatagacca tttccctggc ttgacttgaa aagatcctat tttaatcggc
    16561 aaatgcttcc cgaatagcat gcccaacccc aataaagcaa tgagtatacc cataaccaat
    16621 gaaagaatcg gaaaaatccc tgttagtgcg cttcccaatc ctcctatcaa taaaccagcc
    16681 aatacaaaaa tcgttaaaaa ccccgtggtc atcgctccac caagccctaa tcctttaaaa
    16741 attgcatagc ggaacgaatg atcctttgtt tcgcctccaa ttaaatagga gatataagaa
    16801 ggaagcaagg cgataccaca aggattaaag gccgcaacca ttccagcggt cagaatgaag
    16861 agaaacgaaa aactcataat tccactccta tttgagtcaa cgcttctttt aaatcatcaa
    16921 aggacggtcg aacagaacga tagaatacct cattttcaga attgaccagt acgatctctt
    16981 ccaattgttt gacgccatag gtatccgcaa tttctttacc attctttaaa acatggggcc
    17041 aatccccgcc ataatcctgt ttaaatttcg caaggctttc ttttgtatct gtgttagggt
    17101 ctaaactaac tgtgatcaat tgaacatcgt tcgggtttag ttgatgcatt tccttaaaga
    17161 tttcctcatt gtatatacaa gatggacacc aggttgccat aaaataaatg agtgtgggtt
    17221 tctcattagg taggctgact ggatttcctt gaatgtcttg aacctttgat tcattcgcgg
    17281 tatcagattc tgctccacaa gctgttaaac cgattaacaa caccgtcatt atagcggtga
    17341 aggaaatgcg ttttttcatt caaatcttcc cccatttatt tatcaggccc tcccattaac
    17401 gtttcaataa taggacaggt atacatcgcc ttttcatctg gacacttttc ttttaattcc
    17461 tctaataacc gttggattcg taacaaaccc tgcactttcc gctcgatttc tttggttttt
    17521 tgaacggtaa aggcgtacat atctttacat ctctccccat cttgatcaac cacaccaaac
    17581 aacaggtgga tttcctttag cgagaaatcc aattccttca ttcgtttaat aaaccgtacc
    17641 cgatctgctg tttcctctga atatattcga taccctgatt cgtttctggg aggcccggct
    17701 atcaatcctt tccgctcgta ataccgaacg gtttctttat tcacatcaca cgctttagcc
    17761 aattcactga ttttcatccc catattgtca cctcaataaa aagtataaac cctgtaccat
    17821 agtacacggt caagtcatac attatttttt cttttataga ataatcttat aaaataggtc
    17881 agataaaaaa ccttatttat caagtgttca cataagcttt tttagaagtt taagaataaa
    17941 gatatctgct cttcacgcca agaagccaca ttcttccgtt gaaaaatgcg gctgtcaaaa
    18001 aagttatttt ctttttgatt ctaagatcat ataacaagat tagacgataa agtggtttat
    18061 aaacatctca caaaacgcaa acttacaaca tgtgtgcaat gtccgaagct gccgttggat
    18121 aggcaaatat catttgtttc aattctttgg ttgaaatccc aaaacgaatg gctgttgcaa
    18181 aatgattaat cagttcatcg gcttcattac taatcaaatg agcaccaaca atttgatcat
    18241 gatcttcgtc aatcagcact ttaaacgcag caaagtcctc atttgtccgt ttatacgtaa
    18301 accagtcgga gatgtttttc tgctttactt taatattccg gccagagttt ttggcttcct
    18361 cctcgctcat acctaccgat gccattttag gtacggtaaa tacagcagat ggaatcacgg
    18421 gatattcaat ttttttgctg ttccctttca ataaattaga tgctacgaca tgagaatctg
    18481 cactggctac aggtgtgagg ggcaagccat ccgttgctgc agcatctcca gctgcataga
    18541 cattcgggtt acttacactt tgcaaatact cattaacatg gacaccatgt tttttccttt
    18601 ctatattccc tttttcaaga ttcatatcta aggcagggcc ccgtccagca ccatgaataa
    18661 caatgtctgc ttcaaaccgc gttatatcct ctttttttcg agcgtacaca tgaaactttc
    18721 cttgttcttt ttcaatggat tcaacggaat gttgaagatg tacctgtatg ccaatctctt
    18781 tcgacttttc taaaaggata tctacaagat ctatatcaaa attctggttc tgttgcaaag
    18841 ttgaatttat agtataattt taacaaaaag gaatcttctg tatgaactat ttcagatata
    18901 aacaatttaa caaggatgtt atcactgtag ccgttggcta ctatctaaga tatgcattga
    18961 gttatcgtga tatatctgaa atattaaggg aacgtggtgt aaacgttcat cattcaacgg
    19021 tctaccgttg ggttcaagaa tatgccccaa ttttgtatca aatttggaag aaaaagcata
    19081 aaaaagctta ttacaaatgg catattgatg agacgtacat caaaataaaa ggaaaatgga
    19141 gctatttata tcgtgccatt gatgcagagg gacatacatt agatatttgg ttgcgtaagc
    19201 aacgagataa tcattcagca tatgcgttta tcaaacgtct cattaaacaa tttggtaaac
    19261 ctcaaaaggt aattacagat caggcacctt caacgaaggt agcaatggct aaagtaatta
    19321 aagcttttaa acttaaacct gactgtcatt gtacatcgaa atatctgaat aacctcattg
    19381 agcaagatca ccgtcatatt aaagtaagaa agacaaggta tcaaagtatc aatacagcaa
    19441 agaatacttt aaaaggtatt gaatgtattt acactctata taaaaagaac cgcaggtctc
    19501 ttcagatcta cggattttcg ccatgccacg aaattagcat catgctagca agttaagcga
    19561 acactgacat gataaattag tggttagcta tatttttact ttgcaacaga accagaatta
    19621 atataacgag atatcaattc ctgttgctac atataccgca gctgctgtaa gtatcgttgc
    19681 gatcattttt ccatctccaa tattttatat tttaggggta ggacttttct tcaaattgaa
    19741 aagcccccct tgaattgcgc acagcgtgac cttactattc tgttttctac ctatttatcc
    19801 ttcactctca tcagtcgtaa actatttaat gctaccaaaa tagtagctcc catatcggaa
    19861 agaatcgcta tccaaagggt taaccatccc gggataacta atagtaaggc aattatttta
    19921 attccgatag caaaagtgat gttagcttta atgatattta aagtttttcg actgagtctt
    19981 actgcaaatg gaagcttact taaatcatct cccattaatg caatatcagc tgtttcaatt
    20041 gcagtatccg ttccagcacc gcccattgca attccaacag tagatgcagc aagtgctgga
    20101 gcatcattaa cgccatcgcc aatcatagct acattatcat actccgattg cattttttta
    20161 atataatcta atttatcctg tggcatcaat tcagactgaa tatcagaaac gcctacatgt
    20221 gtaccgattg catttgcagt accttgatta tcacctgtca gcataattgt ttgcttgata
    20281 cctaactgat gaagtttttg aatcacattt ttacttgttt cacgaacctc atctgcaacg
    20341 gcaattacgc cgagaattgt tttttccgtt ccaataatca tggctgtttt tccttggttt
    20401 tgtaggattt tcacattgtt ttcaaaccca aggctaaaat cggaaacatt taattccttg
    20461 aaaagttttg ggcttccaat atagtaagta gttccgttta caatcccttt tatacctcgc
    20521 ccagtaatcg aagtgaattc ttccacttgt acattagaat aagggatatt atcttgctct
    20581 gcctttttca ttattgctga agcaagtgga tgttgtgaac gatattctaa agctgtaatg
    20641 atagagaata gctctttttc ttccacttgg tcatttaata cttcaaaatc tgttaccact
    20701 ggtacacctt ttgtcagtgt tcctgtttta tcaaatgcga ttgccttaat ggctcctaat
    20761 tcttctagat agacaccgcc tttaatcaac acaccttttt tagctgcatt tccaattgcc
    20821 gagacaatcg agattggagt agaaataact aatgcacacg gacatccaac tacaagtacc
    20881 gctaatcctt gataaaccca agtatcccaa cttccaccaa agaataaagg tggaacgact
    20941 gcaacgagcg ccgcaataac cataatgatc ggcgtataat atttcgcaaa tttatctacg
    21001 aatgcttgcg ctggagcgcg ctccccttgt gcttcctcaa ccagatgaat aatcttggag
    21061 atagttgtat cctctacgta tttggtgatt tttacttcaa gtagtccctc ttcgttaagc
    21121 gtacctgcaa atacttcatc atctaccgtt ttggcaacag ggacagattc tcctgttata
    21181 gcagcctggt tgacagccga cacaccattt ataatgatcc catccatggc aattttctcc
    21241 cctggtttga cgatcataat atcacccacg gcaatatcgt ccacatggat cattatttcc
    21301 tgaccattcc gcataacaag tgcttctttt ggggcaatat ccatcaatga acgaatggac
    21361 tgtcttgctc tatccataga aaaacgttca agtgcttcac tgattgcaaa gagaacgaca
    21421 acaatggatg cctctgccca ttcaccaatg atggcagctc caataactgc tacggtcatc
    21481 agggttttca tgtcgaaatc aaagcgtatc aaattttgaa aaccaacttt aaatagtgaa
    21541 tatccgccaa ttacaatcga acctacaaat aacatggaag ttacgaggtt atcttctcca
    21601 tttacaaagt gagaaaggta accaaaagca attagtagtg tggcaaacag caatgtacta
    21661 tgttttttat aaaatggtgt tttctcttct ttatgagcct tagtgtcatc tttaaccctt
    21721 tgtatcgttt gattcgctag tttttcagga gatactttta gattctcaaa agcacctgct
    21781 ttttcaagtt cttcaaccga tgcatttcca tatacatcaa ttttagaagc gccaaagttt
    21841 acttttgcgt cctgaacgcc tggaatcttt ttaacatttt tctcaaactt tcctgcacaa
    21901 tttgcacatg taaatccttg gacccgatag acgttcattt cttcttccat tagtttaacc
    21961 ttttgttcag acattgacct tcacttcttt cttatgtgct agggcgatca tcattatctg
    22021 cctgatatgc tcatcaccta aagaatataa agctagtttt ccttcttttc taaagttgac
    22081 caccccttgc ttataaagcg tacgtaaatg atgagatgca tttgctatcg taacacctaa
    22141 gatatttgct atatcacaaa cacacaactc ttcatcctga cacagagcgt aagtaatttt
    22201 tgctctattt tcatcggcaa tagcctttaa aatttggcta acaccagaaa tatcaactgt
    22261 ttgtaaatcc ccttgtattc gattaacctt ttcttcgtca taacaaaaaa tttcacaagt
    22321 atctttcttt ttcatattat catcccatct tcattcaaat atttatttga gtgtattata
    22381 accattttcg actcatcatg caagcaaata tttgaatgaa aataaaagaa gtaagtaggg
    22441 cataaaattc tagtctcaaa aacgaacgtt tttgacaaaa tgaaattttt aaccattagt
    22501 tcttaaacgt aaaatgtaaa taatgttttt gatatttaaa actgtgtaca gaaaataacc
    22561 attttctata cactctcttt ttatgtctat atatatagcg agtatacata ttttagtgtt
    22621 caataaccca acagaaaatc tatgttcata aatatggtta gaattaagtt atgatacaat
    22681 gaagatgtat ataggaggtt tgtattttga aaataggtta tgcaagagtt tcaactggtt
    22741 tacaaaattt aaatttgcag gaagatcaat taaatcaata tggttgtgaa aagatattta
    22801 gcgaccacat aagtggatca aaaagtaaac gtcctggttt agataaagcc attgaatttg
    22861 cgagggcagg agatacgatt gttgtttgga gactagatag actagggcgt aatatggaag
    22921 atttaatcac attagttaat gaacttaata atcgaggcgt gagttttcat agtttagaag
    22981 aaaatataac aatggataaa tcaagttcta caggacaatt gttatttcat ttattcgcag
    23041 catttgcaga gtttgaacgc aacttaattt tagaacgttc ttcagcagga cgaattgccg
    23101 ctcgtgctag aggacgctat ggaggtcgtc ccgaaaaatt aaataaacaa gatttaaagt
    23161 tactcaaaac actttatgat aatggaacac caattaaaac tattgcagaa caatggaaag
    23221 tttcacgtac cacaatctat cgttatctca ataggttaaa taatcaagaa aataaagata
    23281 aataatatta ctaagtttta agaaagataa aaatagacag gacacaccct aaccatacaa
    23341 aaagaattgt tgaaattata acaattaaaa cgtatgatta gggtgtatat ttattatgga
    23401 gtgaagatga atgattatag gttatgcgag agtatcatcg atagatcaaa atttagaaag
    23461 acaattggat aatttaaaga cgtttggtgt ggagaaaatc tttacagaga aacagtcggg
    23521 aaagtcagtg gaaaatagac ctgtatttca agaagcactc aattttgtca gaatgggaga
    23581 tcgattcgtt gtggaatcta ttgatcgttt aggacgtaac tatgatgaaa ttattgaaac
    23641 tgtgaattat ttaaaagaaa aagacgttca gttaatgatt accagcttac ctatgatgaa
    23701 tgaagtaatt ggcaatccat tactggataa gtttatgaaa gatttaatca ttcaaatatt
    23761 agcaatggtt tcagaacaag agagaaatga aagtaaacgt cgacaagcgc aagggattca
    23821 agttgcgaag gaaaaaggcg tatataaagg gcgcccttta ctttattcac caaatgctaa
    23881 agacccacag aaacgtgtta tttatcatcg cgtggtggaa atgttagaag aaggcaaagc
    23941 gattagtaag attgcgaaag aagttaatat cacaagacaa acagtttata gaattaaaca
    24001 tgataaggga ttatcttgat aaattgattg tcaatgcaaa tgagcgtctc tcacagtgtc
    24061 tcaaattcca taacatatta ttgaattgag attttaataa ttatacaaga aaaaagagta
    24121 cgagttcgca gctttctata tagtaattgt tttactaata aggtgtttta aaatatatta
    24181 taatgtaaaa agtatttgac atttgtatca aaaatattta cactcataaa tgtcaaatac
    24241 tttttacatt tatgaggtgt tataatgaat ttaattcctt ttattattat tttaattttt
    24301 tcttgtttat ggacggctat aactaacaaa tatttacctt cagaaacatt agataaaaaa
    24361 ggacaacaag atcgatacga tgaaagacaa cgtaaaatgt ttattgaaat actggctaaa
    24421 agttttattt ggattgtata ttgtatgtta tttacactag tgcttaaatt tacaggtttg
    24481 tcaccaagta ttgaaggatc ttggttttct caatatccag aaattttctt tataattgta
    24541 gcactatttc ttatgctgtt taattactat actacaaata aaaaatatac atctaaaggt
    24601 taaattaatg aaaaatagaa ttagagaata tagaaaacaa aaaggaattt ctcaagaaac
    24661 tttaagtaaa gaattaaaag tgtctaggca aactattaat gcaatagaaa acaataaata
    24721 tgatcctaca ttgacattag catttaagtt ggcaagattg tttgatacaa ctgtggatga
    24781 attattttct taaccattca tttatcacaa aaagagagtg cgaattcgca ctctcttttt
    24841 gtgtagtagt actattaaat tttgtctcaa taacgaacgt aatttagaaa taatatttat
    24901 tggtatttca agaatatata tataattatt tactaagtcc atttaaaaaa atttgagaga
    24961 acttgttcat aagtttaatt ctttcattaa tattttgttc atgtgtaaag gtaacaattc
    25021 cattaacagc gtttgctgct attttactaa cagcattaac atcattaata caccattcgc
    25081 catttaaatt accctcctta aaaattacat gataagcatc tatatatttg ttttctaatt
    25141 tattcatttt ttcattaatg ctattagttt tataatattc agtgtaaaat tcaattattg
    25201 cgttttgaag tggataatag tattcggttg ttaaagatag ttcattatat aaataaaatt
    25261 tttctctatt agttttacat ttgatttgtt cctttttcca ctgttcttgc catttagatt
    25321 cttctatatt taaaatttct aaaaatagat tttcttttgt tttaaagtga taataaagat
    25381 tccctttact actttctgat aatttaacaa tttctccagt agtagtggca ttatatccat
    25441 tttttataaa taattccttt gcgacaccta gtattttatc tttcaagttc atcacgcctt
    25501 taatgagtat taagtactat caatgatagc acaaaaaatt caaagaataa ttgtataaca
    25561 caatacagcc atttaaattt cgcaagattt tttgttgtaa tatgtaaaaa aatagattat
    25621 aatccttata gaccgatcgc acggtctata aggattggag ggaacttaaa tgatttcatt
    25681 ttttacaaaa actactgata tgatgacatc aaaaaaaaga tggactgcac tagtagtatt
    25741 agctgttagt ttgtttgttg ttacaatgga tatgacaata ttaattatgg ctttaccgga
    25801 attagtaaga gagttagagc cttctggtac ccaacagtta tggatagttg atatatactc
    25861 tcttgtttta gctggcttta taattccatt gagtgccttt gctgataaat ggggaagaaa
    25921 aaaagcatta ttaactggat ttgctttatt tggcctcgtt tcattagcta tatttttcgc
    25981 agaaagtgca gagttcgtaa tagctattcg atttttactt ggtattgcag gtgctttaat
    26041 aatgccaact actctttcaa tgataagagt aatttttgaa aaccctaaag aaagggccac
    26101 tgcattagct gtatggtcaa tcgcttcatc gataggtgct gtttttggac caattatcgg
    26161 aggagcttta cttgagcaat tttcatggca ctcggcattt ttaattaatg taccgtttgc
    26221 gataatagca gttgtagcag gtttattttt attaccagag tctaagttat caaaagaaaa
    26281 gtctcactcg tgggatattc cttctacaat tttatcaatt gcaggcatga ttggactggt
    26341 atggagtatc aaagaatttt caaaagaagg actagcagat attattccat gggttgtaat
    26401 agtattagca attaccatga tagtgatatt tgttaaacgt aatttatcaa gttctgatcc
    26461 aatgttagac gtaagacttt ttaaaaagag atcattttca gctggtacaa ttgctgcatt
    26521 tatgacaatg tttgcaatgg catctgtttt gttattagct tcacaatggt tacaggttgt
    26581 ggaagaactt tctcctttta aagctggctt atacctatta cctatggcaa taggagatat
    26641 ggtgtttgca ccaattgcac ccggattagc ggcgcgattt ggaccgaaaa tagtgttacc
    26701 ttccggaatt ggaattgcag ccattggcat gtttattatg tatttctttg gtcatccatt
    26761 atcatattct ataatggctt tagcattaat tttagttgga gctggtatgg cttcactagc
    26821 agttgcatct gctctaataa tgttagaaac acctacatca aaagcaggta atgcagctgc
    26881 tgttgaagag tctatgtatg accttggaaa tgtttttggt gtagcagtac ttggtagcct
    26941 atcttctatg ctttatcgtg tatttttaga tatttcatct ttttcatcaa aaggtatagt
    27001 tggagattta gctcatgtag ctgaagaatc tgtagtgggc gctgtcgaag tagctaaagc
    27061 tacggggata aaacagcttg caaacgaggc tgtaacatca tttaatgatg cttttgtagc
    27121 aactgcttta gtaggtggga ttatcatgat tatcatttca atagttgtct atttgttaat
    27181 tcccaaatca cttgatataa ctaaacaaaa atagtactaa acatatattt ttagatattg
    27241 tagattagtt tatttttaaa attagtaata gttaaaaagt agaaccatta attttaaatg
    27301 gttctacttt tttattatta agtaaa
//
