LOCUS       NC_021666              14709 bp    DNA     circular CON 07-JAN-2024
DEFINITION  Klebsiella pneumoniae plasmid ColE-LS6, complete sequence.
ACCESSION   NC_021666
VERSION     NC_021666.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225823
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 14709)
  AUTHORS   Villa,L., Capone,A., Fortini,D., Dolejska,M., Rodriguez,I.,
            Taglietti,F., De Paolis,P., Petrosillo,N. and Carattoli,A.
  TITLE     Reversion to susceptibility of a carbapenem-resistant clinical
            isolate of Klebsiella pneumoniae producing KPC-3
  JOURNAL   J Antimicrob Chemother 68 (11), 2482-2486 (2013)
   PUBMED   23800906
REFERENCE   2  (bases 1 to 14709)
  AUTHORS   Villa,L., Capone,A., Fortini,D., Dolejska,M.,
            Rodriguez-Fernandez,I., Taglietti,F., Petrosillo,N. and Carattoli,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2012) Department of Infectious, Parasitic and
            Immune-mediated Diseases, Istituto Superiore di Sanita, Viale Regina
            Elena, 299, Rome 00161, Italy
COMMENT     ##Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler version 2.6
            Sequencing Technology             :: 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/07/2024 10:33:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 17
            CDSs (total)                      :: 17
            Genes (coding)                    :: 14
            CDSs (with protein)               :: 14
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 3
            CDSs (without protein)            :: 3
            Pseudo Genes (ambiguous residues) :: 0 of 3
            Pseudo Genes (frameshifted)       :: 0 of 3
            Pseudo Genes (incomplete)         :: 3 of 3
            Pseudo Genes (internal stop)      :: 0 of 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JX442973.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..14709
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="LS6"
                     /db_xref="taxon:573"
                     /plasmid="ColE-LS6"
     gene            65..769
                     /locus_tag="HS986_RS00005"
                     /old_locus_tag="D647_p33001"
     CDS             65..769
                     /locus_tag="HS986_RS00005"
                     /old_locus_tag="D647_p33001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <824..994
                     /locus_tag="HS986_RS00010"
                     /pseudo=""
     CDS             <824..994
                     /locus_tag="HS986_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            1185..2798
                     /locus_tag="HS986_RS00015"
                     /old_locus_tag="D647_p33002"
     CDS             1185..2798
                     /locus_tag="HS986_RS00015"
                     /old_locus_tag="D647_p33002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_020323136.1"
                     /translation="MNGTSGKGGPSSGGGTDPNSGPGWGTTHTPNGDIHNYNPGEFGNG
                     GSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPALATPGAEGLALSVSGDALSAAVADV
                     LAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSKIVTSLPADTVTETPVSSLPLDQAT
                     VSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKPTKRPGVFSVSIPGLPSLQVSVPKG
                     VPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIRFPKESGQKPVYVSVTDVLTPAQVK
                     QRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDAEDKNIATLNSRIASTEKAIPGARA
                     AVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSLNE
                     MNESLSRDKAALSGAMESRKQKEKKAKDAENKLNEEKKKPRKGTKDYGHDYFPDPKTED
                     IKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFD
                     PKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            2808..3065
                     /locus_tag="HS986_RS00020"
                     /old_locus_tag="D647_p33003"
     CDS             2808..3065
                     /locus_tag="HS986_RS00020"
                     /old_locus_tag="D647_p33003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            3150..3299
                     /locus_tag="HS986_RS00025"
     CDS             3150..3299
                     /locus_tag="HS986_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            4780..6744
                     /locus_tag="HS986_RS00030"
                     /old_locus_tag="D647_p33004"
     CDS             4780..6744
                     /locus_tag="HS986_RS00030"
                     /old_locus_tag="D647_p33004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            6744..7475
                     /locus_tag="HS986_RS00035"
                     /old_locus_tag="D647_p33005"
     CDS             6744..7475
                     /locus_tag="HS986_RS00035"
                     /old_locus_tag="D647_p33005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            7482..8012
                     /locus_tag="HS986_RS00040"
                     /old_locus_tag="D647_p33006"
     CDS             7482..8012
                     /locus_tag="HS986_RS00040"
                     /old_locus_tag="D647_p33006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8040..8219)
                     /locus_tag="HS986_RS00045"
     CDS             complement(8040..8219)
                     /locus_tag="HS986_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            8288..8665
                     /locus_tag="HS986_RS00050"
                     /old_locus_tag="D647_p33008"
     CDS             8288..8665
                     /locus_tag="HS986_RS00050"
                     /old_locus_tag="D647_p33008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(8727..9026)
                     /locus_tag="HS986_RS00055"
                     /old_locus_tag="D647_p33009"
     CDS             complement(8727..9026)
                     /locus_tag="HS986_RS00055"
                     /old_locus_tag="D647_p33009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(9016..9279)
                     /locus_tag="HS986_RS00060"
                     /old_locus_tag="D647_p33011"
     CDS             complement(9016..9279)
                     /locus_tag="HS986_RS00060"
                     /old_locus_tag="D647_p33011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(9585..>9875)
                     /locus_tag="HS986_RS00065"
                     /pseudo=""
     CDS             complement(9585..>9875)
                     /locus_tag="HS986_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(9910..12915)
                     /locus_tag="HS986_RS00070"
                     /old_locus_tag="D647_p33012"
     CDS             complement(9910..12915)
                     /locus_tag="HS986_RS00070"
                     /old_locus_tag="D647_p33012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            13077..13634
                     /locus_tag="HS986_RS00075"
                     /old_locus_tag="D647_p33013"
     CDS             13077..13634
                     /locus_tag="HS986_RS00075"
                     /old_locus_tag="D647_p33013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            13868..14422
                     /gene="aac(6')-Ib"
                     /locus_tag="HS986_RS00080"
                     /old_locus_tag="D647_p33014"
     ARG             13869..14419
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14492..>14707
                     /locus_tag="HS986_RS00085"
                     /pseudo=""
     CDS             14492..>14707
                     /locus_tag="HS986_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     ARG             14505..14707
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.53"
                     /coverage="25.86"
     ARG             13818..14422
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     BGC             1..7798
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(3403..3981)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6745..7472
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 gggcactgtt gcaaatagtc ggtggtgata aacttatcat ccccttttgc tgatggagct
       61 gcacatgaac ccattcaaag gccggcattt tcagcgtgac atcattctgt gggccgtacg
      121 ctggtactgc aaatacggca tcagttaccg tgagctgcag gagatgctgg ctgaacgcgg
      181 agtgaatgtc gatcactcca cgatttaccg ctgggttcag cgttatgcgc ctgaaatgga
      241 aaaacggctg cgctggtact ggcgtaaccc ttccgatctt tgcccgtggc acatggatga
      301 aacctacgtg aaggtcaatg gccgctgggc gtatctgtac cgggccgtcg acagccgggg
      361 ccgcactgtc gatttttatc tctcctcccg tcgtaacagc aaagctgcat accggtttct
      421 gggtaaaatc ctcaacaacg tgaagaagtg gcagatcccg cgattcatca acacggataa
      481 agcgcccgcc tatggtcgcg cgcttgctct gctcaaacgc gaaggccggt gcccgtctga
      541 cgttgaacac cgacagatta agtaccggaa caacgtgatt gaatgcgatc atggcaaact
      601 gaaacggata atcggcgcca cgctgggatt taaatccatg aagacggctt acgccaccat
      661 caaaggtatt gaggtgatgc gtgcactacg caaaggccag gcctcagcat tttattatgg
      721 tgatcccctg ggcgaaatgc gcctggtaag cagagttttt gaaatgtaag gcctttgaat
      781 aagacaaaag gctgcctcat cgctaacttt gcaacagtgc cctgataaat ctggagccgg
      841 tgagcgtggg tctcgcggta tcattgcagc actggggcca gatggtaagc cctcccgtat
      901 cgtagttatc tacacgacgg ggagtcaggc aactatggat gaacgaaata gacagatcgc
      961 tgagataggt gcctcactga ttaagcattg gtaactgtca gaccaagttt actcatatat
     1021 actttagatt gatttaaaac ttcattttta atttaaaagg atctaggtga agatcctttt
     1081 tgataatctc atgaccaaaa tcccttaacg tgagttttcg ttccactgag cgtcagaccc
     1141 ctaattcagg tctgggacac aatggtggtc aggccagtgg gaatgtgaac ggtacatcag
     1201 gtaaaggtgg cccttcatca ggtggtggta cggatccaaa cagcgggccg ggctggggta
     1261 cgacgcatac acctaacggg gatattcata actataaccc gggggagttt ggtaacggcg
     1321 ggagtaaacc cggtggtaat ggcggtaaca gcggcaatca tagcgggagc tctggtggcg
     1381 gacagtcttc ggccaccgcg atggccttcg gtctgcctgc cttggccact ccgggggctg
     1441 aaggactggc tttatccgtt tccggcgatg cgttgtcggc cgctgttgct gatgtgctgg
     1501 ctgccctgaa aggtccgttt aagtttggtc tgtgggggat tgcgatttac ggagtgctgc
     1561 cttctgagat agcaaaagat gatccgaaaa tgatgtcaaa aatcgtgacg tcattgccgg
     1621 cagacacggt aacggagacg ccggtcagct ccctgccgct ggaccaggcg acggtcagcg
     1681 tcactaaacg tgtggcggat attgtgaagg acgagcggca gcatattgcg gttgtcaccg
     1741 gccggccaat gagtgttcct gtggtggatg cgaaaccgac aaaacgtccg ggggtattca
     1801 gtgtgtcgat tccgggtctc ccgtctctgc aggtgagcgt acctaaaggt gttccggccg
     1861 cgaaagcccc gccaaaaggc attattgctg aaaaaggtga ttcacgtccg gctggtttta
     1921 cggccggtgg taactcccgt gaagccgtta ttcgtttccc gaaagagagc ggacagaaac
     1981 cggtctatgt gtcggtgacg gatgttctta ctccggcaca ggtaaaacag cgtctggagg
     2041 aagaaaagcg tcgccagcag gcatgggacg ctgctcaccc ggaagagggg ctgaaaagag
     2101 agtatgataa agcgaaagct gagctggatg ctgaagataa aaatattgcg accttaaaca
     2161 gtcgcattgc atcgacagag aaggcgatcc ccggtgcaag ggctgctgtt caggaagccg
     2221 ataaaaaggt aaaagaggca gaggcaaata aagatgattt tgtgacttat aacccgcctc
     2281 atgaatatgg ctccgggtgg caggatcagg ttcgctatct tgataaggat attcagaatc
     2341 agaatgagaa attaaaagct gcccagacat ctttaaacga aatgaatgaa tccttatcca
     2401 gggataaggc tgcgctttcc ggggcgatgg agagccggaa acaaaaggag aaaaaagcga
     2461 aggatgcaga aaataaatta aatgaggaaa agaaaaaacc tcgtaaggga actaaagatt
     2521 acggccatga ttattttcct gatcccaaga ctgaagatat taaggggttg ggagagttga
     2581 aagagggtaa acctaaaacc cctaaacaag gtggtggtgg taagcgggcc cgatggtatg
     2641 gtgataaaaa gcgtaaaatt tatgaatggg attcccagca cggtgagctt gaagggtacc
     2701 gcgccagtga tggcgaacac ctcggggcat tcgatccaaa aacgggtaag caggttaaag
     2761 ggccggatcc aaaacgaaac attaaaaaat atctttaaga ggtaaatatg gggcttaaat
     2821 tacatattca ttggtttgat aagaaaaccg aagagtttaa aggtggtgaa tactcaaaag
     2881 acttcggtga tgatggttct gtcattgaaa gtctggggat gcctttaaag gataatatta
     2941 ataatggttg gtttgatgtt gaaaaatcat gggtttcgat attacagcca cactttaaaa
     3001 atgtaatcga tattagtaaa tttgattact ttgtatcctt tgtttaccgg gatggtaact
     3061 ggtaagcaaa agttatcaag gatgatttga aatacagact tccggtgttc agggatgaat
     3121 accggggttt ttaaatacag ggaaggtata tgaaaaaggt aaaggttgtt tttcttttta
     3181 tattgatttt ttcaggcttt cttctggtcg catgtcaggc aaactatatc cgggatgttc
     3241 agggtggaac ggtggcacca tcgtcctcct ctgaactgac ggggatcgcg gttcagtaga
     3301 aaagatcaaa ggatcttctt gagatccttt ttttctgcgc gtaatctttt gccctgtaaa
     3361 cgaaaaaacc acctggggag gtggtttgat cgaaggttaa gtcagttggg gaactgctta
     3421 accgtggtaa ctggctttcg cagagcacag caaccaaatc tgtccttcca gtgtagccgg
     3481 actttggcgc acacttcaag agcaaccgcg tgtttagcta aacaaatcct ctgcgaactc
     3541 ccagttacca atggctgctg ccagtggcgt tttgcgtgct tttccgggtt ggactcaagt
     3601 gaacagttac cggataaggc gcagcagtcg ggctgaacgg ggggttcttg cttacagccc
     3661 agcttggagc gaacgaccta caccgagccg agataccaga gtgtgagcta tgagaaagcg
     3721 ccacacttcc cgcaagggag aaaggcggaa caggtatccg ggaaacggca gggttggaac
     3781 aggagagcgc aagagggagc gattcatcgg aaacggtgat gatctttaag tcctgtcggg
     3841 tttcgccact cctgactgat tcatggttga gccaccggct cccacagatg caccgaaaaa
     3901 gcgtctgttt atgtgaactc agtcaggagg gcggagccta tggaaaaacg ccacctgcgt
     3961 ggccttgccg ttttgcctca catgttagtc ccctgcttat tcacggaatc tgtgggtaac
     4021 tttgcatgtg tccgcagcgc ccgccgcagt ctcacggccg gagcgtagcg accgagtgag
     4081 cgaggaggcg caatttcccc ggcacctaca agacggacac cggacgcgct gatgtggcat
     4141 attgtcccct gattaagtct ttatattccc tgataataaa ttaccaggat aggtgaatca
     4201 tatcggtttt tcgctgaaca ttttacgtta acctatctct gttgcttttt tctccttacg
     4261 gagaaataca ggtcatcccc gcgagggcgt ggctgacctc agggggatat cccctgctta
     4321 cgctggctgg acgccaccga cgcacggtct ctccccctct ttctggctcc gtccggctgg
     4381 acgccggcca cgccagaaat tcacccggcc cccgtcaggc tcacgcctga ccacccacaa
     4441 aaatccacgg tgctggacgc acctggcgaa gcagcaaagc tgctcctgat tttgcgggtg
     4501 gtcagccgct cgctatggcg aactctgacg ggggccggaa caccggaaaa gaccgcactg
     4561 gggtgccgcc ttttcctctc acacgctggg gcgtgctcgt tgttcctccg gggctgcgcc
     4621 ttttccgcat ggggcggaaa gaggctggcc tccgtggtga aagctgaacg caatcaccac
     4681 ggacgtgacc gccgccgcca tgccttgggg catgtccgcg gcttgtgcag cgggggctgc
     4741 acatcacgcc ggcaaaccat cgtctgaagg agagagaaca tgtttaatac ggattcgctt
     4801 gcctggaagt ggcacattcc ggagctggcc cggcagattt atccgtgggt cagctggctg
     4861 taccaggagt attacggtct ggccggggct ttcctagtta tcggcctgtt tttcggtctg
     4921 gctgaacttt gggccggacg gatgcgtttt gtggggctga gtcataagga gcgacgggag
     4981 tatgccgatc gctataagcg cgataataaa cggccagcgc cattttcggt gctggcctcg
     5041 ctggattcgc ccgggcggat ggtcagggca cgtcgacatg tctggaacta cgcgtactgg
     5101 ctgaccggcg cggccggtct ggcccttctg ggggggctgg ttgtcgccgt gtttatcgag
     5161 agctggggag aaaccgtcct gcgtccggac ctctacgcaa acgcagatta ttacctgctg
     5221 cagccggcta acctgttcgg gattgcctgg tgcgcgggcg ggctggctgt cgggattgtg
     5281 ttggcgcggc tgctggcgtt cctgctgctt gacggtcatt ttgcggctgc tgacgaggcg
     5341 gtgaacgcga aactgaatca ggagagccgg cgcagcagcc agcggacagg agagatgacc
     5401 gacgtgcgcc acctgcattt cggggagccg gtaccggtta atgcgctggc cgatttttcc
     5461 tcggagcagg cccggcagga gcaggcggtg tttctgggta aggatgagca gggcaagccg
     5521 gtgctggttc cgcgtgatac ctggcgcaag accaacattc agatcctcgg cctgcccggg
     5581 agcggcaaga gcgtgatggc caccaacgcg ctcattcgct gcgtacgcga tttcggggac
     5641 gcggtggtgt acttcgaccc caaaggggac gcatgggcgc cgcacgtctt ccgggcgcac
     5701 tgtccggact tcaccctgct ggatctgcgg ccggggaaac cggcgcagct gaatctgttc
     5761 cgcgatctcg accagtacgc gctgaaaaac ctgctgattg ccgggcttaa cctgggcgag
     5821 accggcgacg tggcggacca ctaccgcatc agcgagcaga aagcggcgaa gctgattgcg
     5881 gagcagtttc cgcagggggc aaacattcag caggtgctgg cggcggcgta cgcgctgccg
     5941 gaggccctga aaaaggacgt gaaggggttg atcactaggc tggaaaacgt cgctgacctg
     6001 agcgtcctgc agacggacag tggcatcgat gtggcgggga ttatcaacgg cggcggctgc
     6061 ctgtacgtta tcggctcgat ggacgacgag gcggtgatcc gtgtgcaaaa aatgctgttt
     6121 gcccgctgcg cgcaaatcat cattgcgcgg gacgagttcc gggagtggcc acacgtcagc
     6181 gtgatgctcg atgaaattaa atatctgctg tcgaagtatg tactgaacgc actggggacg
     6241 ctgcgcagcc gggactgcaa tctgttgctc gcgcaccagt cgctgggcga tttcgggcag
     6301 tgcgggcagg atctgcccgc tgaatttgtg aaaaccacgg tactggataa cacgccgatc
     6361 cgctggtttt accgggcggc cagcctggag tccgcgcagt gggcggcggg gcagaccggg
     6421 gaaatcaggg tggacgtgga gcgccgccgt gccagccggg aggcggggaa cgtggagcat
     6481 atcagcgggg acagcttcat ccagaaggag gcgcggccgc tgtttgacgt gaacaccctg
     6541 caacacctgc cggacgggtt cgcggtcatg accgggctgg gtgtggcccg gatggcgttc
     6601 agcagtccgc tgcgggttga gcgccgggaa atcccgttgc agcgtttccc ggtgctggcg
     6661 aaaaccgatc ccctggcgga gttccggccc ccggccgacg gcggcgggcc gaaagcggat
     6721 gatgattttg cggggattta ctgatggcgc tggagctgta caacgtcagc cacgcgaaac
     6781 gacaggcgcg gaacgcggag aaaacccggc tgaccctgcg ctggttgcgg gaagagctgt
     6841 gttccacggc ggagctggtt gcgcggcggc tggggattgc ggcggtgcag ccggtctacc
     6901 gcttcctcga cagcctggtg gcgaaagggc tgctggtccg gaccaaatat ccggtggacg
     6961 gccgtcaggt cagcgtgtgg gggctgacgc cgcatggcgt ggcgttctcg ttcgacgagg
     7021 acgaaccgct ggcggatgtt attccgtttc agccgtcaag ggtgtcggca gcacatctgc
     7081 cgcaccggct ggccgtgcaa tccctgcgcc ttgatatgga agccagaggg gccaccggct
     7141 ggcgcattct gcaccgtctg agtcttaaag gcatgaaagt gccggacgcc ctggcggagc
     7201 tggacggtaa aacggtggcg tttgaggtgg agcgcaccgt caagagccgt cgccggtatc
     7261 aggaagtggt gtccgggtat ctgttcaacc gcaaagctaa cggcatcgat gaaatctggt
     7321 acatctgccc ggaccgggcg acgcaggtca gggtgcagcg ggcaatcctg tcggtggatg
     7381 aaatcgtgaa cccacagacc ggcgaggccc gcaaaacggc agagctggat cgtgaacggt
     7441 tgtttgcgtg ctttaaattt atgacaacgg agtgagggat tatggcgctg tacatggtat
     7501 ttattgaaga cgcggaggac cggaacggcg agcgctgcat catgccgacc agcgagcatc
     7561 tggaagatat ggtggtgctc gcctggcaga ccggggcgta tgttttctgt tttgtcgacc
     7621 gggcccagca tctggcgatg atgaaatcca tcgggatgta tgacgagcgg ctcaacagcg
     7681 acgaaaaagc cacgtacttt ttcactggta aaaatccgca atgggaacgg aacaaaccca
     7741 caggaatgaa gctgtgtgat tacctctatc gcaaggtgga gcggttcgcc atcgagaacg
     7801 gtgtgcaggt ggttgatgcc gggaagtgct caccggagca gattaacgcg atgattgacg
     7861 tggtgagtga gcggcacggg gaaagcgcgg tgaacgagaa gctgaaagcg gagctgatgc
     7921 gggaatataa cagccgctat tttaacgtgc cggtacctga actgccggag gacaaacctg
     7981 cccgccggtg gtggccgttc ggcaaaaaat aaatgccagc accggccatg ccggtgctgt
     8041 tattcctccc cgagcttatc ccgcatcacc tgccagagtg tttccgcatc ctcgtgtagc
     8101 cgctcgcaca tgtcggccgg ggtatccata tccagctcat tcagtttatc gagcaatagc
     8161 agcgactgct ccttaataaa tttagccata ttgagggctg ttttttcctg ttttgtcatg
     8221 attctttcct tccgggcatg gtgtgcgcct gtcaggtata ctgtctcaaa aatagcgggg
     8281 tgagacaatg gcgtgggtga cggtgagaca ggcgacggaa ctgacgggta aagcccgaag
     8341 ttccctgtat cgggatatgg cgaaaggccg cgtatcatac cgtacggaag ctgatggcgg
     8401 ccgggtggtg gataccagcg agcttatccg ggtgtacggt gagttaagac aggatgagac
     8461 tcacgagcgg gacgagttga gactgtcggg tgagactgaa aaaatggcct ccgacgcgtt
     8521 gatcgcggag ataaaagcac tcagggagga ggtggccggg ctacggcagg aaatgcagtc
     8581 catgagactg ctggaacaca aaccggagac agcagagacc ccggccggaa caccgcgccg
     8641 gtggtggccg tggggaaaac gctgacgcgc tgtgcttgtc caaccggcga cggccacgca
     8701 atgaattgcg tccccgtcac cggttattag agaacaatat ggggattctg gcgctggccg
     8761 accacggcca gaacccggac ttttctggtc tggtcatcaa catcatagag gacatgctgt
     8821 cccatcagac tgatccggcg aacgtcctcg ccatagcgtg agtccacttc atagagtcgc
     8881 gggaagtcgg ccagtttgtc cgccgcagcg agaacccggt cggtaacgtt ctgcgcatcc
     8941 cacagggatg aattttccgc gatatagtca aacagcgtcg ttacatcctc gatggctccc
     9001 tgcttccatt ccacgtcata cggcatcgcg cagttcctga taacggccat gcaggcgctg
     9061 gcggagttgt tccgtggtca tacccggacg cgtgtcagca cgggcggcgg tcactttggc
     9121 gcgaacctga tcttcatact ctgcctgggc cagttcttcg ttagccagtc gctgcaacag
     9181 cgcagctttg tccgggccac cttccggcag tatgcggggc aggctttcag ccagttcccg
     9241 aagaaagttg gcgttttcgt agtgtgtagt gttgctcatt gcggagcctc ccgggttaat
     9301 gcggcaatat gaaggaagtt tagcaggggg cggtctgaaa gaatatggtc gtgtcagtca
     9361 ggctgatgaa gcagaaagtc ggtaaaaaag ggcttacggc atccatttta cgtcaaaaca
     9421 tatgccatgc agttgcgtgc ataggcatgc attaggataa aatttatcgg gcgcgtttcc
     9481 ggcagttttc cgggggggtt gttgcctgtt ttatcccgta gccgccggaa acgccctgag
     9541 cccgtctgag cggtgcgcgt aatgacgcgt tatggtaaat ccacttactg tctgccttca
     9601 tagccatcga gataaacagc tgaaatggtg tcagccagta gccttgattt tttcggtgtg
     9661 aggtctttgc tgcggtaatc ggtacccgca aattgtgttg tgccttggag tgagtttaaa
     9721 aattcctgac tgtgaaactg ctgaatgcgt tgctgcacat cactccgtga ttttccggtc
     9781 gctttatcct ttgcgcccat atcccagaac tgccggaaaa aaggcaccat cattcgtgtt
     9841 gtgtcagctt tctgggtgga aaaattggga tcaaaagggg tctgacgctc agtggaacga
     9901 aaactcacgt taagcaacgt tttctgcctc tgacgcctct tttaatggtc tcagatgacc
     9961 tttggtcacc agttctgcca gcgtgaagga ataatggccg agcatattga tatgtccgtg
    10021 gcaaagcggg gagaggcgtg cgatatcttc atcattcagt gtttcaccct gcgcccggag
    10081 atgatccaga gctgcctgca tataaatagt gttccataac acgacggcgt tagtgaccag
    10141 ccccagagct cccaactgat cttcctgacc gtcggtatat cgttttctta tctcaccttt
    10201 ttgaccgtga cagatggctc tggcaactgc atgacggctt tctccccgat taagctgggt
    10261 cagaatgcgc cggcggtaat cttcatcatc aatataatta agcagataca gcgttttgtt
    10321 gatgcgcccc acttcaatga ttgcctgagt cagtccggag ggacgttcac ttttcagcaa
    10381 tgaacggacc agcactgagg cctgtacttt gcccagcttc agggagcctg cggtccggat
    10441 catttcgtcc cactgaagga ctatttttcg gggatctgat tgccctctgg caatatcatt
    10501 cagcacgcca tagtcggcat catggtccat tcgccagaaa accgaagcac cggcatcagc
    10561 caggcgtgga gaaaactggt atcccagcag ccagaaaagg ccaaagacaa gatcgctggc
    10621 acctgccgta tcggtcataa tttcggttgg attcagcccg gtctcctgtt ccagaaggcc
    10681 ttccagcaca aagatagagt ccctcagcgt ccccggtata acgatgccat gaaagccgga
    10741 atactgatcg gacacaaagt tgtaccaggt gatccctctg ttattaccaa agtatttgcg
    10801 gttcggtccg gcattgattg ttctgactgg cgtaacaaag cgcattccat ctgcagatgc
    10861 cacttctcct ccaccccata tctgtgccag tggcagcgtt gcctgaaaat caaccagtct
    10921 ggcattagcg ctggtgatag tttcagcccg cagatagttc gcttttgtcc agttcagccg
    10981 gtgtcgggtc agtgcaggaa catttgatct gatcagtggt tccagaccga tattgcaggc
    11041 ttcagccatc agcacggcgc tgatgctgac gggcagatca tcaactctgg cactggcttc
    11101 actggcatgg aaaaactcat cagcaaatcc ggtatgggcg ttaatttcga gcagcaactc
    11161 cgttaaatcc accggaggga gcagatcact gatcattttg ctcagtcgtt tcagactgtc
    11221 cggctcatca agactggcga ggggagaaat tgtcaaccgg ggcttcgggc cagaaacatc
    11281 gagttcgaca gcctcatttt cgccaagacg tgcagcaacc tgtctgtaac gactatcaag
    11341 ctgatggccc agagatttta ttgcttcctg cgggtctgtc gggtgcccca aagaacgata
    11401 aaccttaatc cgatttgcct gccagtcagc accctgtagt aatcttgcac gaggatctcc
    11461 ccaccggtta ctgccggtaa cgtagacatc cctccgtctc agactatcct gcagtttact
    11521 gagaaagcag agcgtgtatc cccttcgggt gatatgtttt tccttgttaa tcaccagccg
    11581 tttccatgac tgactgatga tttccgttgg tgcgtcgtca aaaaactgcc gccgtgagct
    11641 gaactcccgg ctgaggtagt cacaggcatt cagagtggta accccggcag gtgcggatga
    11701 aaatttaacg gtattcagca gatggggcag gaaacgacga acgcgcccgt actgctccac
    11761 catttcgtca tgaaaattat cgtctgaggg ccgggcaatt tcacggacaa gcgtgatgat
    11821 ttcagccagc ttttgcctag ggatgtagct gaacacctca gcacgaatcg attcgtccgg
    11881 tgtttcttct ttcagcaagt acgaacatgc gctggcgagc gccaatgcag atttatccag
    11941 atccttcagc gagcggagcc gttttttctg cccaatcttt ctggcgtcac ggatgataac
    12001 ggccagcatg gcgtccagaa cgtccagtgc atcatccagc gccagcgttt cccatgcaag
    12061 gacaaaggca accagaaccg ccatcctttt ctgcggtgac atcctggcaa tattgaacac
    12121 cgaagtcata ccagcataac gtgcgagatt tttcaggcgc acagccggga gtgtactcag
    12181 gttttcagca tgcaggccaa aatcgttcag agttttccag cgttcaattg cttcattaaa
    12241 cgccggacca ctgatggtca cagggccttt tttcagtgat tccagtaaag acaggcggct
    12301 gcaatcagtt ggccccagca gcatctccag ctgtgaacgc tgttcggctg acggtatcag
    12361 tgccagtttg ttccacaggc gcaacgtcgc cttttccctt acctctgaaa tcaaccgggt
    12421 cagcgtggtg gctccgggga gaataatacg atgttgcata agccaccctg tcgccaggtc
    12481 gaaaagcagg ccaggacgtt cgttgcttat ccagctccgg gtatataaaa gacgggtaag
    12541 gcgaaatgtc cagggccagg caaattcacg atactgatag tgctgacgta tcagcgctgc
    12601 atgctcacgg cgggtatttt ccctctgacc gtattctgca agaacggtga tatcacgaat
    12661 cccgagctgt ctggcggtaa aatgccggac gccggaagga atatgattca tgtcagtaag
    12721 aaaagtgccc agaaaacgca cacacccgat ttgcagggca ataccaagtc gattgtgatc
    12781 accccggctt ttcccgataa attctttatc cgcttcatca agatgaaaat aacgcgccag
    12841 ctgaagttca tcgggttcgc cagtgaacct gccataactc tcaacctgct cagtggtcaa
    12901 aaaatcaacg ggcatatcgg cctccctgcc tgacggcttt tttaacacaa ctgcaaccgt
    12961 tcgaaatatt ataaattatc agacatagta aaacggcttc gtttgagtgt ccattaaatc
    13021 gtcattttgg cataatagac acatcgtgtc tgatattcga tttaaggtac atttttatgc
    13081 gaatttttgg ttatgcgcgg gtctcaacca gccagcagtc cctcgatatt cagatcagag
    13141 cgctcaaaga tgcaggggta aaagctaacc gcatctttac cgacaaggca tccggcagtt
    13201 caacagatcg ggaagggctg gatttgctga ggatgaaggt ggaggaaggt gatgtcattc
    13261 tggtgaagaa gctcgaccgt cttggccgcg acaccgccga catgatccaa ctgataaaag
    13321 agtttgatgc tcagggtgta gcggttcggt ttattgacga cgggatcagt accgacggtg
    13381 atatggggca aatggtggtc accatcctgt cggctgtggc acaggctgaa cgccggagga
    13441 tcctagagcg cacgaatgag ggccgacagg aagcaaagct gaaaggaatc aaatttggcc
    13501 gcaggcgtac cgtggacagg aacgtcgtgc tgacgcttca tcagaagggc actggtgcaa
    13561 cggaaattgc tcatcagctc agtattgccc gctccacggt ttataaaatt cttgaagacg
    13621 aaagggcctc gtgatacgcc tatttttata ggttaatgtc atgataataa tggtttctta
    13681 gacgtcaggt ggcacttttc ggggaaaagt gcgcggaacc cctatttgtt tatttttcta
    13741 aatacattca aatatgtatc cgctcatgag acaataaccc tgataaatgc ttcaataata
    13801 ttgaaaaagg aagagtatga gtattcaaca tttccaaaca aagttaggca tcacaaagta
    13861 cagcatcgtg accaacagca acgattccgt cacactgcgc ctcatgactg agcatgacct
    13921 tgcgatgctc tatgagtggc taaatcgatc tcatatcgtc gagtggtggg gcggagaaga
    13981 agcacgcccg acacttgctg acgtacagga acagtacttg ccaagcgttt tagcgcaaga
    14041 gtccgtcact ccatacattg caatgctgaa tggagagccg attgggtatg cccagtcgta
    14101 cgttgctctt ggaagcgggg acggatggtg ggaagaagaa accgatccag gagtacgcgg
    14161 aatagaccag ttactggcga atgcatcaca actgggcaaa ggcttgggaa ccaagctggt
    14221 tcgagctctg gttgagttgc tgttcaatga tcccgaggtc accaagatcc aaacggaccc
    14281 gtcgccgagc aacttgcgag cgatccgatg ctacgagaaa gcggggtttg agaggcaagg
    14341 taccgtaacc accccagatg gtccagccgt gtacatggtt caaacacgcc aggcattcga
    14401 gcgaacacgc agtgttgcct aacccttcca tcgaggggga cgtccaaggg ctggcgccct
    14461 tggccgcccc tcatgtcaaa cgttaaacat catgagggaa gcggtgatcg ccgaagtatc
    14521 gactcaacta tcagaggtag ttggcgtcat cgagcgccat ctcgaaccga cgttgctggc
    14581 cgtacatttg tacggctccg cagtggatgg cggcctgaag ccacacagtg atattgattt
    14641 gctggttacg gtgaccgtaa ggcttgatga aacaacgcgg cgagctttga tcaacgacct
    14701 tttggaaac
//
