LOCUS       NC_019150              27069 bp    DNA     circular CON 04-MAY-2024
DEFINITION  Staphylococcus aureus plasmid p18805-P03, complete sequence.
ACCESSION   NC_019150
VERSION     NC_019150.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224400
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27069)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Complete nucleotide sequence analysis of plasmids in strains of
            Staphylococcus aureus clone USA300 reveals a high level of identity
            among isolates with closely related core genome sequences
  JOURNAL   J Clin Microbiol 48 (12), 4504-4511 (2010)
   PUBMED   20943864
REFERENCE   2  (bases 1 to 27069)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2010) Laboratory of Human Bacterial Pathogenesis,
            Rocky Mountain Laboratories/NIAID/NIH, 903 S. 4th Street, Hamilton,
            MT 59480, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009947955.2-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 03:41:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 32
            CDSs (total)                      :: 32
            Genes (coding)                    :: 24
            CDSs (with protein)               :: 24
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 8
            CDSs (without protein)            :: 8
            Pseudo Genes (ambiguous residues) :: 0 of 8
            Pseudo Genes (frameshifted)       :: 4 of 8
            Pseudo Genes (incomplete)         :: 4 of 8
            Pseudo Genes (internal stop)      :: 2 of 8
            Pseudo Genes (multiple problems)  :: 2 of 8
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002132.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27069
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="18805"
                     /db_xref="taxon:1280"
                     /plasmid="p18805-P03"
     gene            1..983
                     /locus_tag="HS257_RS00005"
                     /old_locus_tag="SUA_0002"
                     /pseudo=""
     CDS             1..983
                     /locus_tag="HS257_RS00005"
                     /old_locus_tag="SUA_0002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <1003..1292
                     /locus_tag="HS257_RS00010"
                     /pseudo=""
     CDS             <1003..1292
                     /locus_tag="HS257_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1491..1871)
                     /locus_tag="HS257_RS00015"
                     /old_locus_tag="SUA_0004"
     CDS             complement(1491..1871)
                     /locus_tag="HS257_RS00015"
                     /old_locus_tag="SUA_0004"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2156..2848)
                     /locus_tag="HS257_RS00020"
                     /old_locus_tag="SUA_0006"
     CDS             complement(2156..2848)
                     /locus_tag="HS257_RS00020"
                     /old_locus_tag="SUA_0006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2958..3152
                     /locus_tag="HS257_RS00025"
                     /old_locus_tag="SUA_0007"
     CDS             2958..3152
                     /locus_tag="HS257_RS00025"
                     /old_locus_tag="SUA_0007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4269..4886
                     /gene="cadD"
                     /locus_tag="HS257_RS00030"
                     /old_locus_tag="SUA_0009"
     ARG             4270..4883
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4905..5252
                     /locus_tag="HS257_RS00035"
                     /old_locus_tag="SUA_0010"
     CDS             4905..5252
                     /locus_tag="HS257_RS00035"
                     /old_locus_tag="SUA_0010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5409..5501
                     /locus_tag="HS257_RS00040"
     CDS             5409..5501
                     /locus_tag="HS257_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5673..6645)
                     /locus_tag="HS257_RS00045"
                     /pseudo=""
     CDS             complement(5673..6645)
                     /locus_tag="HS257_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /name="oxidoreductase"
     gene            6769..7188
                     /locus_tag="HS257_RS00050"
                     /old_locus_tag="SUA_0013"
     CDS             6769..7188
                     /locus_tag="HS257_RS00050"
                     /old_locus_tag="SUA_0013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7714..8559)
                     /gene="blaZ"
                     /locus_tag="HS257_RS00055"
                     /old_locus_tag="SUA_0014"
     ARG             complement(7718..8559)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8666..10423
                     /gene="blaR1"
                     /locus_tag="HS257_RS00060"
                     /old_locus_tag="SUA_0015"
     ARG             8667..10420
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10413..10793
                     /gene="blaI"
                     /locus_tag="HS257_RS00065"
                     /old_locus_tag="SUA_0016"
     ARG             10414..10790
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11057..11635
                     /locus_tag="HS257_RS00070"
                     /old_locus_tag="SUA_0017"
     CDS             11057..11635
                     /locus_tag="HS257_RS00070"
                     /old_locus_tag="SUA_0017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            12305..12979
                     /locus_tag="HS257_RS00075"
                     /old_locus_tag="SUA_0019"
     CDS             12305..12979
                     /locus_tag="HS257_RS00075"
                     /old_locus_tag="SUA_0019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13148..13719)
                     /locus_tag="HS257_RS00080"
                     /pseudo=""
     CDS             complement(13148..13719)
                     /locus_tag="HS257_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(13995..14789)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HS257_RS00085"
                     /old_locus_tag="SUA_0022"
     ARG             complement(13999..14789)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14882..15412)
                     /gene="sat4"
                     /locus_tag="HS257_RS00090"
                     /old_locus_tag="SUA_0023"
     ARG             complement(14886..15412)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15409..>16044)
                     /locus_tag="HS257_RS00095"
                     /pseudo=""
     CDS             complement(15409..>16044)
                     /locus_tag="HS257_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16185..16859)
                     /locus_tag="HS257_RS00100"
                     /old_locus_tag="SUA_0026"
     CDS             complement(16185..16859)
                     /locus_tag="HS257_RS00100"
                     /old_locus_tag="SUA_0026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16916..17092)
                     /locus_tag="HS257_RS00105"
                     /old_locus_tag="SUA_0027"
                     /pseudo=""
     CDS             complement(<16916..17092)
                     /locus_tag="HS257_RS00105"
                     /old_locus_tag="SUA_0027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17106..17843)
                     /locus_tag="HS257_RS00110"
                     /old_locus_tag="SUA_0028"
     CDS             complement(17106..17843)
                     /locus_tag="HS257_RS00110"
                     /old_locus_tag="SUA_0028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17836..18765)
                     /locus_tag="HS257_RS00115"
                     /old_locus_tag="SUA_0029"
     CDS             complement(17836..18765)
                     /locus_tag="HS257_RS00115"
                     /old_locus_tag="SUA_0029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18881..19762)
                     /locus_tag="HS257_RS00120"
                     /old_locus_tag="SUA_0030"
                     /pseudo=""
     CDS             complement(18881..19762)
                     /locus_tag="HS257_RS00120"
                     /old_locus_tag="SUA_0030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19759..>20136)
                     /locus_tag="HS257_RS00125"
                     /old_locus_tag="SUA_0031"
                     /pseudo=""
     CDS             complement(19759..>20136)
                     /locus_tag="HS257_RS00125"
                     /old_locus_tag="SUA_0031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20194..20868)
                     /locus_tag="HS257_RS00130"
                     /old_locus_tag="SUA_0032"
     CDS             complement(20194..20868)
                     /locus_tag="HS257_RS00130"
                     /old_locus_tag="SUA_0032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21342..22808
                     /gene="msr(A)"
                     /locus_tag="HS257_RS00135"
                     /old_locus_tag="SUA_0033"
     ARG             21343..22805
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22907..23806
                     /locus_tag="HS257_RS00140"
                     /old_locus_tag="SUA_0034"
     CDS             22907..23806
                     /locus_tag="HS257_RS00140"
                     /old_locus_tag="SUA_0034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24292..24900
                     /locus_tag="HS257_RS00145"
                     /old_locus_tag="SUA_0035"
     CDS             24292..24900
                     /locus_tag="HS257_RS00145"
                     /old_locus_tag="SUA_0035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25146..25484
                     /locus_tag="HS257_RS00150"
                     /old_locus_tag="SUA_0036"
     CDS             25146..25484
                     /locus_tag="HS257_RS00150"
                     /old_locus_tag="SUA_0036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25489..25674
                     /locus_tag="HS257_RS00155"
                     /old_locus_tag="SUA_0037"
     CDS             25489..25674
                     /locus_tag="HS257_RS00155"
                     /old_locus_tag="SUA_0037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25901..26644)
                     /locus_tag="HS257_RS00160"
                     /old_locus_tag="SUA_0038"
     CDS             complement(25901..26644)
                     /locus_tag="HS257_RS00160"
                     /old_locus_tag="SUA_0038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22908..23803
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21343..22808
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22908..23806
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(14883..15400)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15707..16008)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7715..8559)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1349..1496
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..983
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.492"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1115..1284
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25902..26644)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa gggttagaaa acgatggtct actcattcaa aaacgacgtg
      301 gtttaaataa accaaatatt ctatatttaa tgaaacctat tgtcacagaa cgtgatattt
      361 acaaaataga aaaagaagaa aacgatgttg aaccttacgg cgagaaggaa gttcgaaaat
      421 cgaacgtcca gaagttcgaa aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag
      481 ttcgaaaatc gaacactaat gatactgact ttaatgacat tgactttaat gatactgaga
      541 ataatgatat gaatgacttg aatgatataa agtacaaaaa tgaaattagt aatcattcaa
      601 atcattcaaa tcaatttaca cataattttg atgataaaga aatgctattg caagaattcc
      661 cagaacaact aactaattat ttattaaaat atgattatag agatttagaa atcataaagg
      721 ctgttattct taaagcaaaa aaatcattta attcaaggca tgaagatatg cattacatgt
      781 tagaggacat tgaggatgaa atattaactt ctttaaaaag acttaaaaaa gctatacatg
      841 ataggggagt taaaggccaa aaggaaacaa tcaagtcaat gcaagcttat ttaatgcaaa
      901 caattctaac tgaacttgaa gaaacacatg ccctttatat gcgccgtaaa aacatgaaac
      961 aatataatat ctttaatcaa taattcaaat gattttataa cactcgaaga gacatcaaaa
     1021 tattccgtta aatcatctga ctttttaact gatgacgacg aaaaaaatca agaaattgta
     1081 agtgatttag aaaaaggttt gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa
     1141 caaaagcata aaattttaaa cttagacgat gccgaagatg gtaatttgat taatacaagt
     1201 gatgaagata aaacgacaga cgaagaaaaa aagcacattc aattaccgca atttggaatt
     1261 tcgaaaagca aaattattat ttaagacatt agtgataact gatgtctttt tttattgttt
     1321 ttctgtaaaa aagtgctgtc ttatttttgt gacaaatgct gtatgtagtg tcacaaaagt
     1381 gtgacactac agctttgtat gatatcactt taaaataact taaaaccctt ggaatgtctg
     1441 gccttgccag atctatcatt tttgaatgat agcaaatttc ccttatgctc ttacggagat
     1501 tttagagtta aattaaaatt tctaagtttt tgataagaaa agccctgcag gaatttagaa
     1561 aaacatgggg aagttttaaa gtattttatg ctaattttta aatttgcatg taaatgggca
     1621 gtatctaaaa aattagtcac tgattttgct gaaatttttg tttgtgaaat tagcatatat
     1681 ttatttggct catatttgcg ttttaagaga ctgtatagat ttttaagtac aaaacctata
     1741 tgatttgcct ctaagtcttc aaaatgcctc ttaaaatcca aaataaaagt gtttaatatt
     1801 gtaataagga ttgctatttt tataaaagga gagatatcat gaagattaaa actttcgcta
     1861 cttttactca tcgtcaatta gataaacaag ttaataggtt tttaaagaat gatattcatg
     1921 tattagaaat tcaaacacac agtaattggt tatatatttc agctattgtt ttttatgagg
     1981 ataaataagg aacatcgtat ttatgccgaa aaaatttatt gatgttgaga agaaccctta
     2041 actaaacttg cagacgaatg tcggcatagc gtgagctatt aagccgacca ttcgacaagt
     2101 tttgggattg ttaagggttc cgaggctcaa cgtcaataaa acaattggaa taaaatcaac
     2161 ctacagagca tccagctgca aatgcagttc cgcaaactgc ttcacataca ccgccggcta
     2221 ttggatttac gattgcccat actccacagt agtgagcaca tgcataaagt ccagccatac
     2281 tacaagcgaa tgctttgccg ttccatttga atcctgcata tgttaccggt ctgtttttat
     2341 caactttttc agccttatat tcaacgtaat ttttgttaat aagtattttt ccctctttgt
     2401 tttcagtcat acttcttttt tcggcaatga attttgtgat ttttttgttg tagttatcat
     2461 atattgtttc agaaactaca atttcttttg ttttttcatt tttataagcg ttattagcta
     2521 tgtagccata tgcattttta tcatttgctt ctgtagctag atattttaat ttagaatttt
     2581 tgtcttctag ctttattttt ttaaatcctt cttttttcat ttgcttttcg aatttttgca
     2641 tatcttcatt tttattttgc aattgttcta gaaaacttat ttctttcttg gtcatttgtg
     2701 atacttcgat gtttttgctt ttcaattttt ctttttgatt ttctagtaaa gaactttttt
     2761 gttcttcatt tgcgtaagca ttagaaaaat tcgcgctaaa taccagtagg aacaaggaaa
     2821 ttattgaaaa taattttata attttcattt gatacctcca agataataag atattttaat
     2881 tgtataagta agcgctttat aaaatcaata tttattttaa tatatttata aacatatttt
     2941 tgaaaggagt ctattttatg aatgaaaatt tagaaaaata tataaaaagt ttgccacttt
     3001 taggtttgtt aattagtatt ttgttaattg ttttattctt ttttatttta gatgttgatg
     3061 aagatttatt cgtggttttt ttatactgtt tattgccttt gatagttaat ttgtctattt
     3121 atggttttta tgtttttgtt aaaagaaagt aagattatga ataattttgt ttttaatttg
     3181 tatgctttga gggggttgga aaacggtagg tgtatagatt agatttcttg ttttttttga
     3241 aacgagtgtg aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt
     3301 tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg
     3361 ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat
     3421 atttatttgg ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata
     3481 tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat
     3541 aaaagctacc ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct
     3601 ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt
     3661 tttcaagaat gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc
     3721 tcaagccgtt tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca
     3781 catgtcgatt tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac
     3841 gaattttaga cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaag
     3901 tagaaccgaa aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact
     3961 tcctaaaact gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt
     4021 gtctccatgt ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag
     4081 aacccttaac taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt
     4141 cgacaagttt tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata
     4201 aagcacctat gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga
     4261 ggtgtattat gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg
     4321 atttattagt aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag
     4381 atatttatgt tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4441 cttttgtatt aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa
     4501 tttatcttgg aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa
     4561 aagaattgaa tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag
     4621 caagttgtgg cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta
     4681 ctaatttatt acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg
     4741 cacaaaaatt agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga
     4801 ttatggctat tatttatata gctttaggtt tatttattat tattgaaaat gacactattc
     4861 aaacaatttt aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata
     4921 cttgtgatgt gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag
     4981 atgataaatc taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga
     5041 aaatcatatt atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat
     5101 tgaaaatgag tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac
     5161 ttgattttta taaagatgga aagatggcat attattttat taaagacgat gaaataagag
     5221 agtttttctc taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat
     5281 aaaaaacaaa gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca
     5341 cagatggtat aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt
     5401 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     5461 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     5521 gccagcatcg aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt
     5581 taatcatttt cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa
     5641 ttaatagtaa atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa
     5701 tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg
     5761 tatagaagtg aatttcctat attccattca tttgctaact tactccatat atcttcacgg
     5821 atattatgat caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac
     5881 ggtaatatat tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct
     5941 tgataattta gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa
     6001 taatcaaaaa tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt
     6061 gcacctaatt ttttttgcga tttctatttg cttttctttt cttacgatag cagtgatatt
     6121 ttcatatcca attttatgta aaatttgtat agcaacactg cccacaccac ctgtagcccc
     6181 agacactaaa atttcaggtt gtgatttgat attcattcca tatttttcta gttcaaaaat
     6241 tgataatgct gccgtaaaac cggctgtgcc atataccata gactctttaa tagacatttc
     6301 ttggggaata ggaacaatcc actctccagg cacttgtgca tattctgaaa atccacctgt
     6361 atgtgtcacg ccaacatcat aaccagtaac taatacatta tcgccttctt taaacttatc
     6421 attcgaactt gattcaacaa tacctgcaaa atctatacca ggaatcatag gataatctct
     6481 aattacaccg cctttatatt gtaaagctag catatcctta taatttattg aagagtatac
     6541 cacttttact aatacatcac ccttcgataa atgagattca tcaacttttt ctactttata
     6601 actaacattt gatgcacttt ttctcactac taccgcattg aacatttatt agccttcttt
     6661 cacaattgtt ttgtagaagt atgtttttgt tgcaaaacta ttttcctaca aaacttatca
     6721 tgatatgata agcgagtcaa tactaatgat ttaagagagg ttttagttgt ggaattagat
     6781 aattgtataa attatttgtt gagtacttct cagaatagag tttttaaaca ttttaaaagt
     6841 ttattaagtc cctataatat tactccagca gaatatggtg ttttgaattg cttgattaat
     6901 agtaatttga atacacctaa agcgattggt aatactttaa atttagaacc ttcaacaata
     6961 tctggaatat tagataagat gtccaaaaag gatctaataa cacgtcaaac tgataatgaa
     7021 aatagaagaa ctgtgctaat aaacagtaca aataaagcaa aagacttatg gccaacatta
     7081 gaaaagaaag cctatcaact taataatcat tacttcgcta atttaactaa tgaagaaact
     7141 gtagtgttta aaaagatatt actaaagata aataaaacta cgttttaatt tttacgttat
     7201 aaaaaagttg aagtgcgaat tataatcgag taaatataaa tgatagctta gcttaattat
     7261 atattaaagc caactatact tttattcccg aaaaacctac tatccaaatt tctaagatac
     7321 tttagcctct ataataaaca tattgtaata taatttatgt attatttagg tttaccctaa
     7381 tcgaacaata aaaaatactt gtaaaatgct attgtcactt tgcttgatat atgagaatta
     7441 tttaacctta taaatgagaa aaaagcaacg cactttaaat aagatacgtt gctttttcga
     7501 ttgatgaaca cctataatta aactattcat ctattattta tgattttttg tatatacaat
     7561 atttctagtt tgttaaagag aattaagaaa ataaatctcg aaaataataa agggaaaatc
     7621 agtttttgat atcaaaatta tacatgtcaa cgataataca aaatataata caaactataa
     7681 gatgttatca gtatttatta tgcatttaga atattaaaat tccttcatta cactcttggc
     7741 ggtttcactt atcaacttat catttggctt atcactttta ttgtctttat tcgtaaaaat
     7801 gactaaaaca ataggttcag attggccctt aggataaaca aaagcaacat catttctaga
     7861 agcatatgtt attgcttgac cacttttatc agcaacctta tagtcttttg gaacaccatc
     7921 tttaattaaa gtgtctccgt ttttattatt aaacattaaa tcaagtaaga aatttttatt
     7981 ttttttgctt aattttccat ttgcgataag tttatttaaa gtcttgccga aagcagcagg
     8041 cgttgaagta tcttttttgc tctttggtga atagtaattt aattctatct catatctaac
     8101 tggatttgtt actttatctc ctagttcttt tagacgttgt ttaacttttt tgattccacc
     8161 gatttctttt ataattttat tgtttgctgt attatcacta tatgtcattg aagcctcaat
     8221 aagttctttt aaagtgatat cttttcctac atatttttct aaaataggag aataagcaac
     8281 tatatcatct ttgttaatat gtactttttt atttaactta ttataaggta cttgttctaa
     8341 caaaatagca ctatttatcg cttttgaagt cgaagcatag gcaaatctct tatctgaatt
     8401 aaattttact tccttaccac ttttagtatt taaagcataa acaccaatat gagcattata
     8461 ttttttttct aaatcattta actctttggc atgtgaactg tttgaattac atgcacttaa
     8521 aactaaagca attacaatta aaaatattaa ctttttcaaa ataaaccctc cgatattaca
     8581 gttgtaattt ttataaatca ataatattac aattgtaata ttgatgtcaa ttgtttatta
     8641 taaatatttg aaagaaggtg tcaaaatggc taaattacta ataatgagcg tagtaagctt
     8701 ttgttttata tttctattgt tagtattttt taggtacata ttaaaacgct attttaatta
     8761 tagtttaaat tataaagttt ggtatctaac tatgcttgct ggattaattc cttttatccc
     8821 aattaaattc tcttttataa aatttaataa tgtgaataat caagcgccca cagttgaaag
     8881 taagtcacac gatttgaacc ataacataaa taccaccaaa cctattcaag agttcacaac
     8941 agatatccat aagtttaatt gggattcaat tgataatatc tgcacagtta tttggatagt
     9001 tttagttatt attttaagtt ttaaattttt gaaagcctta ttatatctta aatatttaaa
     9061 gaaacagtca ctttatctaa acgaaaatga aaaaaataaa atagatacga tacttttcaa
     9121 ccatcaatat aaaaaaaata ttgtgattcg aaaagcagag gctattcaat ctccaataac
     9181 tttttggtat gggaaatata ttattttgat tcctagttca tattttaaaa gtgtaattga
     9241 taaaagacta aaatatataa tactgcatga atatgctcat gctaaaaata gagatacttt
     9301 acatttaatt atctttaata tcttctctat tattatgagt tacaatccat tagtacatat
     9361 tgtaaaaaga aagataattc atgacaatga agtagaagcc gatagatttg tccttaataa
     9421 tattaacaaa aatgaattta aaacttatgc ggaatctatt atggactccg tattaaaaac
     9481 cccattttcc aacaaaaata tattaagcca ttcatttaat ggtaaaaaat cattactcaa
     9541 aagtagatta attaatataa aagaagccga tctgaaaaag cagtcaaaat taattctaat
     9601 ttttatttgt atttttactt tttttatcat gataattcaa agccagtttt taatggggca
     9661 atccttaact gattataatt ataaaaagcc cttacaaagc gattaccaaa ttttagatga
     9721 aagtaaaaat tttggttcaa atagtggatc tttcgttatg tacagcatga agaaagacaa
     9781 atactatatt tataatgaaa aagaaagtag aaaaagatat tctcctgatt caacttacaa
     9841 aatttattta gcactgtttg gacttgaccg tcatattata agtgataaaa attcacgtat
     9901 gtcatggaat cataaacatt atcttttcga gtcttggaat aaggaacaag atttaaatac
     9961 agcaatgcaa aattcagtta attggtactt cgaacgtatt agtaatcaaa taccaaagaa
    10021 ctatactgcg gctcaactca agcaattaaa ttatggtaat gaaaatttgg gaagttataa
    10081 aagctattgg atggaagata gtttgaaaat atctaatctt gaacaagtaa tagtttttaa
    10141 aaatatgatg gaacaaaata accattttag taaaaaagca aagaatcaat tatcttcttc
    10201 attattgatt aagaaaaatg aaaagtatga actgtatggg aaaacaggta caggtatagt
    10261 aaacgggaag tataataatg ggtggtttgt aggttacgta attacaaatc atgataagta
    10321 ttattttgct acacatttat cagatggaaa cccgtctggg aaaaatgctg aattaataag
    10381 tgaaaaaata ttaaaaggaa tgggtgtttt aaatgaccaa taagcaagtt gaaatatcta
    10441 tggctgaatg ggatgttatg aatataatat gggataaaaa atcagtatca gctaatgaaa
    10501 ttgtagttga aattcaaaaa tataaagaag ttagtgataa aacgattaga acattaatca
    10561 caagactata taaaaaagag attataaaac gatacaaatc agaaaatatt tatttttact
    10621 catcaaatat taaagaagac gatattaaaa tgaaaactgc taaaaccttt cttaataaac
    10681 tgtatggagg ggatatgaaa agtttagtgc tgaattttgc gaaaaatgaa gaattaaata
    10741 acaaagaaat tgaagaattg cgagacattt taaatgatat tagtaaaaag taattagagg
    10801 tatgtttcaa acataataca tatgtaaacc atacttgact cttattaaat tagttttgtt
    10861 aatgacattt aaaatatatt attaaagatg agagtgtcca gaaaataacc attttctgta
    10921 cactcttgtt ttttgtctaa ataagtaagt attacataga attatgtgtt caaaaaccca
    10981 acaaaaaatc tatgttcaca aaagacctcg taatcaagtt atggtacact aaaggtgtat
    11041 ataggaggtc tgtattttga aaataggtta tgcaagagtt tcaactggat tacaaaattt
    11101 gaatttacag gaggatcgat taaatacata tggttgtgaa aagatattta atgaccatat
    11161 gagtggttca aaaagtaagc gacctggttt agataaagca attgaatttg cgaggtcagg
    11221 agatacgatt gttgtttgga gattagatag actaggacgg aacatggagg atttaatcac
    11281 gttagttaat gaacttaacg aacgaggtgt gagttttcat agtttagaag aaaatataac
    11341 gatggataaa tcaagttcta caggacaatt attatttcat ttattcgcag catttgcaga
    11401 gtttgaacgt aatttaattt tagagcgatc atcagccggt cgaattgcag cacgtgctag
    11461 aggccgatat ggaggtagac ctgaaaaatt aaataaacaa gatttaaact tacttaagac
    11521 actttatgat aatggtacgc caattaaaac aattgcagag cagtggcaag tttcacgtac
    11581 aactatttat cgttatctca ataaattaga ggcaaaagag aataaaaaca agtagagcaa
    11641 ctaatctagc ttactataat gaatctacta aataatttta tatatcatta acatacaaag
    11701 actttgattc aatgtcactc gatgtaaaag agacgttctg acagcgtcta aaatctcata
    11761 atattttcct gttatgagat tttaataata acacaagaaa aaagcgtaca aattcgtacg
    11821 cttttttaat ataatacctg tttcactaat gaacgtttta agtatcttca tcattaactg
    11881 aaactacagt aataatactc gtcaacaata ttagtatagt taaaatagaa agacttagga
    11941 ctggcataac cgaactaaaa ttatatttga aatataaaag tgctaatgaa gagagaaatg
    12001 taaaaataat aaataccaaa gaccattttt ctaatttatt cattggcttc acctctttga
    12061 acttttatat aatcatagga gatattttta ctacgattta taaaaaataa gaagataatc
    12121 attattaaag aaacgattaa tataatgttg aatcctatag tatcacctaa ttcgtttaca
    12181 cctttgccta atatcggaga tacaaagctt tgtattaata atgaaagaga tgcccatata
    12241 gtaaatgagg ttctgttgca aagttgaatt tatagtataa ttttaacaaa aaggagtctt
    12301 ctgtatgaac tatttcagat ataaacaatt taacaaggat gttatcactg tagctgttgg
    12361 ctactatcta agatatgcat tgagttatcg tgatatatct gaaatattaa gggaacgtgg
    12421 tgtaaacgtt catcattcaa cggtctaccg ttgggttcaa gaatatgccc caattttata
    12481 tcaaatttgg aagaaaaagc ataaaaaagc ttattacaaa tggcgtattg atgagacgta
    12541 catcaaaata aaaggaaaat ggagctattt atatcgtgcc attgatgcag agggacatac
    12601 attagatatt tggttgcgta agcaacgaga taatcattca gcatatgcgt ttatcaaacg
    12661 tctcattaaa caatttggta aacctcaaaa ggtaattaca gatcaggcac cttcaacgaa
    12721 ggtagcaatg gttaaagtaa ttaaagcttt taaacttaaa cctgactgcc attgtacatc
    12781 gaaatatctg aataacctca ttgagcaaga tcaccgtcat attaaagtaa gaaagacaag
    12841 gtatcaaagt atcaatacag caaagaatac tttaaaaggt attgagtgta tttacgctct
    12901 atataaaaag aaccgcaggt ctcttcagat ctacggattt tcgccatgcc acgaaattag
    12961 catcatgcta gcaagttaag cgaacactga catgataaat tagtggttag ctatattttt
    13021 ttactttgca acagaaccag catttgtttt aatatttgtt ccaaagagcc atcatggctt
    13081 tgacagagct cttcttctat gcaaatgctt ttaatccgat ccacacgaaa attcctatat
    13141 tcatttctta gcctgcaaaa ccgattaagt accagttctg ttcataaaac cccagtgata
    13201 taggctctat cattctgctt tccggttctt gccctcctga tgcaggatat tgaattgata
    13261 ttaccctttt attgcagatt gcagtctgaa ttgctgcaat aacgttatcc gccaatgtat
    13321 ttttctgtcc agatgtgctg tacacgttaa tactgttctc caactcctgt gcatagtttt
    13381 tttcaccatg cttcaaaata gatttgattt tatacatagc tgaatcaaaa tcctttataa
    13441 atgattcatc tccatggcaa tttaaaaatt tccctgctgt aatcaatgca cccacttccg
    13501 ccgctgtaaa cattaccggc agaagtagga agccctctac aagaaaatat ccttttccgg
    13561 cctcagatcc aattggtatt ccggcttctt caagtgtccg gatatctctg taaactgtcc
    13621 ttaagcttat attaaatcgc tgtgcaattt ctttggcagg aattattttt ttgattgcag
    13681 ctgaataaga atagaggtta ctctgttaat cctgttcaaa ttttattcct cctctgtgac
    13741 ttccataaaa agtatatcct atgcgttctt aagctagctg ctgttagtgc ttctcattgc
    13801 accctggtta taaaagccat actcacaaac ctcttcacca aaactcttta catctctaat
    13861 atagaactct atctagcgaa cttttagaaa agatataaaa catcagagta tggacagttg
    13921 cggatgtact tcagaaaaga ttagatgtct aaaaagcttg tagttaaagc tttttagaca
    13981 tctaaatcta ggtactaaaa caattcatcc agtaaaatat aatattttat tttctcccaa
    14041 tcaggcttga tccccagtaa gtcaaaaaat agctcgacat actgttcttc cccgatatcc
    14101 tccctgatcg accggacgca gaaggcaatg tcataccact tgtccgccct gccgcttctc
    14161 ccaagatcaa taaagccact tactttgcca tctttcacaa agatgttgct gtctcccagg
    14221 tcgccgtggg aaaagacaag ttcctcttcg ggcttttccg tctttaaaaa atcatacagc
    14281 tcgcgcggat ctttaaatgg agtgtcttct tcccagtttt cgcaatccac atcggccaga
    14341 tcgttattca gtaagtaatc caattcggct aagcggctgt ctaagctatt cgtataggga
    14401 caatccgata tgtcgatgga gtgaaagagc ctgatgcact ccgcatacag ctcgataatc
    14461 ttttcagggc tttgttcatc ttcatactct tccgagcaaa ggacgccatc ggcctcactc
    14521 atgagcagat tgctccagcc atcatgccgt tcaaagtgca ggacctttgg aacaggcagc
    14581 tttccttcca gccatagcat catgtccttt tcccgttcca catcataggt ggtcccttta
    14641 taccggctgt ccgtcatttt taaatatagg ttttcatttt ctcccaccag cttatatacc
    14701 ttagcaggag acattccttc cgtatctttt acgcagcggt atttttcgat cagttttttc
    14761 aattccggtg atattctcat tttagccatt tattatttcc ttcctctttt ctacagtatt
    14821 taaagatacc ccaagaagct aattataaca agacgaactc caattcactg ttccttgcat
    14881 tctaaaacct taaataccag aaaacagctt tttcaaagtt ggcgtataac atagtatcga
    14941 cggagccgat tttgaaacca caattatgat agaatttaca agctataagg ttattgtcct
    15001 gggtttcaag cattagtcca tgcaagtttt tatgctttgc ccattctata gatatattga
    15061 taagcgcgct gcctatgcct tgccccctga aatccttaca tacggcgata tcttctatat
    15121 aagcgtaccg gttccaattt tttcgcagtt taacttttcc gacgcattta tcgtcttggt
    15181 agtaaagata tattatctta tcagtattgt caatatattc aaggcaatct gcctcctcat
    15241 cctcttcatc ctcttcgtct tggtagcttt ttaaatatgg cgcttcatag agtaattctg
    15301 taaaggtcca attctcgttt tcatacctcg gtataatctt acctatcacc tcaaatggtt
    15361 cgctgggttt atcgatatct ttcaggtgcc ctgctttcat ttctgtaatc actgttcccg
    15421 cctctcttct atatcagcgg catatgtgct atccaggcag ccggttttac cagtgtattt
    15481 tttatacatg tccctggtat attttgttat attcctatca tactccggat aggcataatg
    15541 aagcctttcc gccacctcac cggataccgc cctgaacaat tgatggcata gaaataatgc
    15601 ttcccatatg ttttcatagg aatccatccg gtaggtggac aaaagtttct cccacaaatc
    15661 ctcggatata tacctttcaa taaacttata gttcttgcct acacttcatt taaagcctgt
    15721 ttcgatgccg accttccatg atatcattct cagcagctca tggcgaacaa tctgattaaa
    15781 atgatcaata gcaaataaaa tttccttacg gcacaatcct ttaataacat aaggtgttac
    15841 attccaaaat tcattgcagc aatcatcata ctcccttgcg cttggctttc ttacatgata
    15901 atctatatca gtcggaacta tgtccctttt aattctacaa tctttatcaa ttagaacctt
    15961 tattaattta tcgcccttta ggtaattatc taactcttcc aagggcaata aggtaagatc
    16021 aattttattg taatcatcaa atagctataa tagatttaga ggtaaagaaa ttaaatacat
    16081 tgaagagcag aaagatttta caaaagagta ttttaataaa aatgatggtt ctgttgcaaa
    16141 gtaaaaaata tagctaatca ctaatatatc atgtcagtgt tcgtttaact tgctagcatg
    16201 atgctaattt cgtggcatgg cgaaaatccg tagatctgaa gagacctgcg gttcttttta
    16261 tatagagcgt aaatacactc aatacctttt aaagtattct ttgctgtatt gatactttga
    16321 taccttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt attcagatat
    16381 ttcgatgtac aatggcagtc aggtttaagt ttaaaagctt taattacttt aaccattgct
    16441 accttcgttg aaggtgcctg atctgtaatt accttttgag gtttaccaaa ttgtttaatg
    16501 agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct
    16561 aatgtatgtc cctctgtatc aatggcacga tataaatagc tccattttcc ttttattttg
    16621 atatacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt cttccaaatt
    16681 tgatataaaa ttggggcata ttcttgaacc caacggtaga tcgttgaatg atgaacgttt
    16741 acaccacgtt ctcttaatat ttcagatata tcacgatagc tcaatgcata tcttagatag
    16801 tagccaacgg ctacagtgat aacatccttg ttaaattgtt tatatctgaa atagttcata
    16861 cagaagactc ctttttgtta aaattatatt ataaattcaa ctttgcaaca gaacctccta
    16921 actgtattac caccttaaaa gtagttgcag acgcacttcc taaatcgtca gcagtgttta
    16981 accacatatc atcaacaata atcatatgac ctgttgatga tactggagca aattctgtca
    17041 acccttcaac tacacctaaa ataaatgctt taatctgctc tataaaaccc atttttctcc
    17101 tccttttaac ttatatcagt ttttttaaag tatgagaata atataattac actgaatata
    17161 gatgtaacaa ttatgataat taaagataat agaaatggat aagtattagg taatgttcct
    17221 ctagatatgt ctccaactgc agcccaagga aataatcctc tatgttcaga attagcagtc
    17281 attaaattta tcaaagtaat tattatggtt aaaacaattg tgggaacata atttttaaaa
    17341 tatatcgaca aaataattat tggtggagat aatatccata ataacactcc gccaataaca
    17401 aatgtaaaga atgaatcaat tattaaactc tggcttaacc cttgaaaatg caatagcata
    17461 cctagcatta aagttagcaa ccatgcaata acagatagtg tttgaatcca caagaataat
    17521 aatattattt tacttactaa aaaactttct ctagatatag gtataattaa taagtttttt
    17581 aaagtatctt ctatatattc tcttccaaac aaataggcta ttataacccc atatagagga
    17641 ggtccaataa ttagcatatg atataaactg acttcttcaa ataactgttt aaatacaata
    17701 ttaggagtcg gtactttcgt ccgcatacta ataaaagaag ctacaaccac cataaaaggt
    17761 gctacgcatg tacctaaaat acttattaga aacatatatg atctttttaa cttaataaat
    17821 tctgtacgga gtagattatc caattgtgcc acctcctact aagtcttcga aataagtttc
    17881 tagattatct tctatcactc tcatctggaa aacatcaata ttgtttaata ctaataatct
    17941 attaatttct tgttgtctat caatatgtga ataaatttta aattcgccat tttctttaat
    18001 tttatagtca taaattccga agttagtttc caacaaacat gcaacttttt cttcatctga
    18061 tactgatata cttataaatt gtctgttctt tttttttaaa tcttcataca taatttcttc
    18121 taacaaaact ccgttatgaa taatacccac cttgtctact aactgctcta tttctgacaa
    18181 tatatgactt gaaattaaaa tggttatatt tctagattga gccagatcct taatcaactt
    18241 tctaatttct tttatgccaa taggatctaa tccattcgtc ggctcatcaa gtatcaataa
    18301 ttcgggattg tgcaataaag ctctcgcaat ccctaaacgt tgcttcatac ctaaagaata
    18361 atttttaaac aattttactt tttcagaagc tagtcctact atttctaaca cttcttcaat
    18421 tgcattttct ttttgtatac ctaatatttt agcatttata gttaagttct ctttagctgt
    18481 caaattacta taaaaacctg gcgtttcaac catagcacca atatttttta aaatttcagt
    18541 tttattactt tcgaactctt tttcaaatat tttaatatta cctttcgtag gtttaattaa
    18601 gcctaaaagc attcttatag tagttgtttt gcctgcacca tttcttccta aaaaaccata
    18661 aatttgtcca ctttcaacag ttatactcaa attattaact gctatctgac ttccatattg
    18721 ctttgttaag ttatttattt caattatatt attcaaattt ttcacctctg gcacctttct
    18781 tagtttgttg ttacctttat cttacgcgcg attagaaaag gctgccttta tctattctta
    18841 caaaaacagc cgctaatctt acaaaaatga aagattggag ttatttaaat tgaatggtga
    18901 atattgaacc atcgtttaat gtagatgtag cacttacttt atggcctaag cgctttgaga
    18961 ttgtgctgac aatatataaa ccaataccgc ttgatttctc acttattcta ccgttatagc
    19021 ccgagaaacc tttatcaaag attttcggta aatcactcgc attaatgccg ataccgttat
    19081 ctcggattga taatttcttt gtattttcgt caaacgtaat ccacacatct ttgccacgtg
    19141 catattttaa tgcattgttt aatatttgct caatcataat tgatgcccat ttggcatctg
    19201 ttaatataac cgcttcactt ttctcataat gcaactttgt ttgatgatga ataaactgta
    19261 tcgcataacg tttaatcagt ggtcgaatta attcatctac actcacttcc ataaagacca
    19321 tgtatgtctt ttggttcatg agtttcaaat agttcagtgc aagattcgtg taattatcaa
    19381 tttgtaagac ttcattacgc acgttagaaa tcacgtgttc atcaggatct tcaagcagta
    19441 actttgatgc tgtaatcggt gtcttgattt gatgcaccca cattaaaaaa tatgactcta
    19501 actcactttg gtagttaata aagtcattac gaagtttatg gttttcgatt cttaaatctt
    19561 cgttctgttc ctgtagtgtt tattcttttt taaagttcat gtaatggata ccccagtaaa
    19621 tcattgaaac aaacaataca atacctagac caatcatata tgcttgcatc ggcacattat
    19681 acatgaataa tataaagtag aataaagcac aagtaaggat gacaatataa atttcacgtt
    19741 ggattgattt caagaaattc atacgtcacc tacacgatat ccgacatttt tcttcgtttc
    19801 gataaaatct gtaagtccta gtttttgtag ctttttgcgt aaacgtgtaa tgttgacagc
    19861 aagcgtattg tcatcaatga agtgttctga ttcccagcat ttttcgatta acgcattacg
    19921 actgacgaat ttgcccttgt tctggaataa gctatgcatg atttgcaatt cagtgtgtgt
    19981 caggtctatg gtttcttcat taaatttaag ctttgctgca tcaagtagta actcgcaatc
    20041 atctactgtt aaattattaa cttgagtggt gaaatcatac gtgcggcgta atagtgcttg
    20101 aatcttagta attgtaacag tcatattaaa tggctggttc tgttgcaaag taaaaaatat
    20161 agctaatcac taatatatca tgtcagtgtt cgtttaactt gctagcatga tgctaatttc
    20221 gtggcatggg gaaaatccgt agatctgaag agacctacgg ttctttttat atagagcgta
    20281 aatacattca atacctttta aagtattctt tgccgtattg atactttgat atcttgtctt
    20341 tcttacttta atatgacggt gatcttgctc aatgaggtta ttcagatatt tcgatgtaca
    20401 atgacagtca ggtttaagtt taaaagcttt aattatttta gccattgctg ccttcgttga
    20461 aggtgcctga tctgtaacta ccttttgagg cttaccaaat tgtttaatga gacgtttgat
    20521 aaacgcatat gctgaatgat tatctcgttg cttacgcaac caaatatcta atgtatgtcc
    20581 ctctgtatca atggcacgat ataaatagct ccattttcct tttattttga tatacgtctc
    20641 atcaatacgc catttgtaat aagctttttt atgctttttc ttccaaattt gatataaaat
    20701 tggggcatat tcttgaaccc aacggtagat cgttgaatga tgaacgttta caccacgttc
    20761 tcttaatatt tcagatatat cacgatagct caatgcatat cttagatagt agccaacggc
    20821 tacagtgata acatccttgt taaattgttt atatctgaaa tagttcatac agaagactcc
    20881 tttttgttaa aattatatta taaattcaac tttgcaacag aaccgtattt tatgagtaca
    20941 ctctaaatta aggagatgta taatcaatct aaaattgtat ttttatactt ttgttatata
    21001 atctttctac ttagagatat attgtaaaaa aaccaacaaa atgttatatt aacattacta
    21061 ttttatcgat gaaggaggat taaaatgaca gcttctatga gactcaaata aacctttttg
    21121 aatacaaaac taaattaatt caaaaaggct tgtccgcaat acacactcat aggatgactt
    21181 atgtcatttt ttatccttcg ataggaataa taaacgcttt caaatactaa aacatcataa
    21241 taaattttta agtgtttgaa agtgtaatgt gaatgagacg ggagtagcct gtctcatttt
    21301 tttgcgtaca cgtcctttaa atatacaagg agtgtataaa tatggaacaa tatacaatta
    21361 aatttaacca aatcaatcat aaattgacag atttacgatc acttaacatc ggtcatcttt
    21421 acgcttacca atttgaaaaa atagcactta ttgggggtaa tggtactggc aaaaccacat
    21481 tactaaatat gattgctcaa aaaacaaaac cagaatctgg aacagttgaa acggttggcg
    21541 aaattcaata ttttgaacag cttaacatgg atgtggaaaa tgattttaac acgttagacg
    21601 gtagtttaat gagtgaactc catataccta tgcatacaac cgacagtatg agtggtggtg
    21661 aaaaagcaaa atataaatta gctaatgtca tatcaaatta tagtccgata ttacttttag
    21721 atgaacctac aaatcacttg gataaaattg gtaaagatta tctgaaaaat attttaaaat
    21781 attactatgg tactttaatt atagtaagtc atgatagagc acttatagac caaattgctg
    21841 acacaatttg ggatatacaa gaagatggca caataagagt gtttaaaggt aattacacac
    21901 agtatcaaaa tcaatatgaa caagaacagt tagaacaaca acgtcaatat gaacagtata
    21961 taagtgaaaa acaaagattg tcccaagcca gtaaagctaa acgaaatcaa gcgcaacaaa
    22021 tggcacaagc atcatcaaaa caaaaaaaca aaagtatagc accagatcgt ttaagtgcat
    22081 caaaacaaaa aggcacggtt gagaaggctg ctcaaaaaca agctaagcat attgaaaaaa
    22141 gaatggaaca tttggaagaa gttgaaaaac cacaaagtta tcatgaattc aatttcccac
    22201 aaaataaaat ttatgatatc cataataatt atccaatcat tgcacaaaat ctaacattgg
    22261 ttaaaggaag tcaaaaactg ctaacacaag tacgattcca aataccatat ggcaaaaata
    22321 tagcgctcgt aggtgcaaat ggtgtaggta agacaacttt acttgaagct atttaccacc
    22381 aaatagaggg aattgattgt tctcctaaag tgcaaatggc atactatcgt caacttgctt
    22441 atgaagacat gcgtgacgtt tcattattgc aatatttaat ggatgaaacg gattcatcag
    22501 aatcattcag tagagctatt ttaaataact tgggtttaaa tgaagcactt gatcgttctt
    22561 gtaatgtttt gagtggtggg gaaagaacga aattatcgtt agcagtatta ttttcaacga
    22621 aagcgaatat gttaattttg gatgaaccaa ctaatttttt agatattaaa acattagaag
    22681 cattagaaat gtttatgaat aaatatcctg gaatcatttt gtttacatca catgatacaa
    22741 ggtttgttaa acatgtatca gataaaaaat gggaattaac aggacaatct cttcatgata
    22801 taacttaaaa actatacact aatttatatt gaatattagg ttcatttata tcaatataaa
    22861 aaatacgttc acaagaaaaa tataatagaa ataaggatcc aataaaatga ctcgacataa
    22921 tgaaattatt aaatgtgcag aaaaatatca attacacatc caacctcaaa caatctcatt
    22981 gaatgaatcg ggacttgatt ttcaagttgc atttggaaaa gataaacatg gagtagaatg
    23041 ggttttgaga ctaccaagaa gacctgacgt ttataaacga acaaaacccg aaaaacaaac
    23101 ggtagacttc ttacagaaga atgtttcatt tgaaataccg aagtggaaag tacatgcaaa
    23161 agaccttatt gcttacccaa aacttacagg taaacccgca gccacaatag atccagaaat
    23221 acaaaattat gtatgggaaa ttgaacacaa accattacca gaaaacttta ttaacacatt
    23281 agctgaaaca ctcgtagatt tacacaacat accagaagaa aacattaacg ttcagcatat
    23341 aaatatcaaa accatacaag aaataaaaaa tgactttcaa agaagaatga ataaagttaa
    23401 agaaacttat ggcgtatcag atgaattatg gaacagatgg aaacaatggt tagaaaacga
    23461 cgaactatgg cctcgacatg cgaccatgat acatggggac ttacatccag gacatataat
    23521 ggtagataac caagcaaacg tcacaggtct catagactgg actgaagcaa cccactccga
    23581 cccatcaatg gactttatag gacaccatcg tgtattcgac gacgaaggat tagagcaact
    23641 tataacagca tacggtaaag ctggaggtga aatatggcca cgaatgaaag agcatataat
    23701 agaactcaat gcagtattcc caatgtttat cgctgagttt gctatggaat caggagaatc
    23761 ggcgtatgaa acgatggcat tgaaagagtt aggtatgaaa gagtagaact tatattaaaa
    23821 gaggcccatt ttaaagacga aggcaatcct gatgaaattt taaaactgcg tttaattagt
    23881 gatggtcttt ggttttctat aatgtattaa atatctggac atggaacaaa tgcaacaaat
    23941 ggaaagaatc gttttcgaaa tttctaactc cttaaatcag gaggataaat aaacggtcat
    24001 tttcattgaa agcacttata taaatttcat caattttaat acctaccgta aatacatttc
    24061 ataagtatta aacagatgat taaaattttt agttaattta aatatttatg atagagatga
    24121 ccttcaaatg aacggttctg ttacaaagaa aaaatctata tttattttta gtaagtttta
    24181 attatagata tgtacacttt gagtacaccc taaccataca aaaagaattg ttgaaattat
    24241 aacaattaaa acgtatgatt agggtgtata tttattatgg agtgaagatg aatgattata
    24301 ggttatgcga gagtatcatc gatagatcaa aatttagaaa gacaattgga taatttaaag
    24361 acgtttggtg tggagaaaat ctttacagag aaacagtcgg gaaagtcagt ggaaaataga
    24421 cctgtatttc aagaagcact caattttgtc agaatgggag atcgattcgt tgtggaatct
    24481 attgatcgtt taggacgtaa ctatgatgaa attattgaaa ctgtgaatta tttaaaagaa
    24541 aaagacgttc agttaatgat taccagctta cctatgatga atgaagtaat tggcaatcca
    24601 ttactggata agtttatgaa agatttaatc attcaaatat tagcaatggt ttcagaacaa
    24661 gagagaaatg aaagtaaacg tcgacaagcg caagggattc aagttgcgaa ggaaaaaggc
    24721 gtatataaag ggcgcccttt actttattca ccaaatgcta aagacccaca gaaacgtgtt
    24781 atttatcatc gcgtggtgga aatgttagaa gaaggcaaag cgattagtaa gattgcgaaa
    24841 gaagttaata tcacaagaca aacagtttat agaattaaac atgataaggg attatcttga
    24901 taaattgatt gtcaatgcaa atgagcgtct ctcacagtgt ctcaaattcc ataacatatt
    24961 attgaattga gattttaata attatacaag aaaaaagagt acgagttcgc agctttctat
    25021 atagtaattg ttttactaat aaggtgtttt aaaatatatt ataatgtaaa aagtatttga
    25081 catttgtatc aaaaatattt acactcataa atgtcaaata ctttttacat ttatgaggtg
    25141 ttataatgaa tttaattcct tttattatta ttttaatttt ttcttgttta tggacggcta
    25201 taactaacaa atatttacct tcagaaacat tagataaaaa aggacaacaa gatcgatacg
    25261 atgaaagaca acgtaaaatg tttattgaaa tactggctaa aagttttatt tggattgtat
    25321 attgtatgtt atttacacta gtgcttaaat ttacaggttt gtcaccaagt attgaaggat
    25381 cttggttttc tcaatatcca gaaattttct ttataattgt agcactattt cttatgctgt
    25441 ttaattacta tactacaaat aaaaaatata catctaaagg ttaaattaat gaaaaataga
    25501 attagagaat atagaaaaca aaaaggaatt tctcaagaaa ctttaagtaa agaattaaaa
    25561 gtgtctaggc aaactattaa tgcaatagaa aacaataaat atgatcctac attgacatta
    25621 gcatttaagt tggcaagatt gtttgataca actgtggatg aattattttc ttaaccattc
    25681 atttatcaca aaaagagagt gcgaattcgc actctctttt tgtgtagtag tactattaaa
    25741 ttttgtctca ataacgaacg tttataacgc aatcatgatg agagtattaa tacagttaat
    25801 tatttgaaat actttagttt acataatcga tgattaccag aagttctcac tatataaaag
    25861 acactaaaat tttataactt ttagtgccta atcaattatt ttagctacca aacaaacgac
    25921 tccaaaaccc ctttttaggt tccgtttctt cactcttttc ttctatatca ctatcattgt
    25981 catttagatt agctggaacg tcttcttttt ttgcttcttc accttgtgta ctttcgtcgc
    26041 tttgacttcc agatatatcc ttatattgaa tctctgtttc tttagtttct tcctgatctc
    26101 tgttaatatt tacaggatta gtagtatatg ttttttcttg tgcatcaacg ttttgtctag
    26161 tgttagtaga tgtatcaaag ggataattaa ggtgtttttc tttttctaat tgattttcta
    26221 atttttgaat ctttttatta ctctctaatg ccagaacttg ctgattttca agcaattttg
    26281 atctttcttg caactctttt ctgtaaaatt caattgttgt ttcatgacga ctttcttgtt
    26341 tttcaatttg attatttaaa gtatcaatct gatttttaag gatttctact atttgagcat
    26401 cgcttttcga ttcaaaatta atattatccg accctttttt ttgtttgtct tcagtagtac
    26461 tttcaaaacc atatttcttt ttattttcat ttactctttg aatgattttt tctatatcgg
    26521 tatcttcttt aataaacgaa gtgttttcct gttttattgt ctctatattc aatcgcttaa
    26581 tattattaaa aatcgtttgc ttactaaccc ctaattcttc actcaacttt ttcacacttt
    26641 tcatatcatc aaccctttat aaaatgttta taaacccttg ataaaatatt ataagcttat
    26701 aatgcttaat aataaagtga ttaataaata aaaataaaca tccatcaacc tttttatcaa
    26761 gggtttatga aaggtttatg atatttatca agggtttata aacccttgat aaagctatat
    26821 tttccctttt ataagtttat ttaaagtgct ataataaact taatataaca aaaaccccaa
    26881 ctactggtaa tagtcggggt ttggtaataa aacgtttaga aactgtttat ttatataatt
    26941 ttcgatactt gtattatata atgaataata tcttagtgca agcacctaaa tcattaaata
    27001 aatgtaaagc taaataaaaa cgttttatta cctcttacca aactaaaata tggaaagagg
    27061 ttttttgtc
//
