LOCUS       NC_018963              27067 bp    DNA     circular CON 04-MAY-2024
DEFINITION  Staphylococcus aureus plasmid p18810-P03, complete sequence.
ACCESSION   NC_018963
VERSION     NC_018963.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224390
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27067)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Complete nucleotide sequence analysis of plasmids in strains of
            Staphylococcus aureus clone USA300 reveals a high level of identity
            among isolates with closely related core genome sequences
  JOURNAL   J Clin Microbiol 48 (12), 4504-4511 (2010)
   PUBMED   20943864
REFERENCE   2  (bases 1 to 27067)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2010) Laboratory of Human Bacterial Pathogenesis,
            Rocky Mountain Laboratories/NIAID/NIH, 903 S. 4th Street, Hamilton,
            MT 59480, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009948065.2-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 04:38:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 32
            CDSs (total)                      :: 32
            Genes (coding)                    :: 25
            CDSs (with protein)               :: 25
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 7
            CDSs (without protein)            :: 7
            Pseudo Genes (ambiguous residues) :: 0 of 7
            Pseudo Genes (frameshifted)       :: 3 of 7
            Pseudo Genes (incomplete)         :: 4 of 7
            Pseudo Genes (internal stop)      :: 2 of 7
            Pseudo Genes (multiple problems)  :: 2 of 7
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002141.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27067
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="18810"
                     /db_xref="taxon:1280"
                     /plasmid="p18810-P03"
     gene            1..983
                     /locus_tag="HS273_RS00005"
                     /old_locus_tag="SUJ_0002p2"
                     /pseudo=""
     CDS             1..983
                     /locus_tag="HS273_RS00005"
                     /old_locus_tag="SUJ_0002p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <1003..1292
                     /locus_tag="HS273_RS00010"
                     /pseudo=""
     CDS             <1003..1292
                     /locus_tag="HS273_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1491..1871)
                     /locus_tag="HS273_RS00015"
                     /old_locus_tag="SUJ_0005p2"
     CDS             complement(1491..1871)
                     /locus_tag="HS273_RS00015"
                     /old_locus_tag="SUJ_0005p2"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2156..2848)
                     /locus_tag="HS273_RS00020"
                     /old_locus_tag="SUJ_0006p2"
     CDS             complement(2156..2848)
                     /locus_tag="HS273_RS00020"
                     /old_locus_tag="SUJ_0006p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2958..3152
                     /locus_tag="HS273_RS00025"
                     /old_locus_tag="SUJ_0007p2"
     CDS             2958..3152
                     /locus_tag="HS273_RS00025"
                     /old_locus_tag="SUJ_0007p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4268..4885
                     /gene="cadD"
                     /locus_tag="HS273_RS00030"
                     /old_locus_tag="SUJ_0009p2"
     ARG             4269..4882
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4904..5251
                     /locus_tag="HS273_RS00035"
                     /old_locus_tag="SUJ_0010p2"
     CDS             4904..5251
                     /locus_tag="HS273_RS00035"
                     /old_locus_tag="SUJ_0010p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5408..5500
                     /locus_tag="HS273_RS00040"
     CDS             5408..5500
                     /locus_tag="HS273_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5672..6643)
                     /locus_tag="HS273_RS00045"
                     /old_locus_tag="SUJ_0011p2"
     CDS             complement(5672..6643)
                     /locus_tag="HS273_RS00045"
                     /old_locus_tag="SUJ_0011p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6767..7186
                     /locus_tag="HS273_RS00050"
                     /old_locus_tag="SUJ_0012p2"
     CDS             6767..7186
                     /locus_tag="HS273_RS00050"
                     /old_locus_tag="SUJ_0012p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7712..8557)
                     /gene="blaZ"
                     /locus_tag="HS273_RS00055"
                     /old_locus_tag="SUJ_0013p2"
     ARG             complement(7716..8557)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8664..10421
                     /gene="blaR1"
                     /locus_tag="HS273_RS00060"
                     /old_locus_tag="SUJ_0014p2"
     ARG             8665..10418
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10411..10791
                     /gene="blaI"
                     /locus_tag="HS273_RS00065"
                     /old_locus_tag="SUJ_0015p2"
     ARG             10412..10788
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11055..11633
                     /locus_tag="HS273_RS00070"
                     /old_locus_tag="SUJ_0016p2"
     CDS             11055..11633
                     /locus_tag="HS273_RS00070"
                     /old_locus_tag="SUJ_0016p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            12303..12977
                     /locus_tag="HS273_RS00075"
                     /old_locus_tag="SUJ_0018p2"
     CDS             12303..12977
                     /locus_tag="HS273_RS00075"
                     /old_locus_tag="SUJ_0018p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13146..13717)
                     /locus_tag="HS273_RS00080"
                     /pseudo=""
     CDS             complement(13146..13717)
                     /locus_tag="HS273_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(13993..14787)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HS273_RS00085"
                     /old_locus_tag="SUJ_0021p2"
     ARG             complement(13997..14787)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14880..15410)
                     /gene="sat4"
                     /locus_tag="HS273_RS00090"
                     /old_locus_tag="SUJ_0022p2"
     ARG             complement(14884..15410)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15407..>16042)
                     /locus_tag="HS273_RS00095"
                     /pseudo=""
     CDS             complement(15407..>16042)
                     /locus_tag="HS273_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16183..16857)
                     /locus_tag="HS273_RS00100"
                     /old_locus_tag="SUJ_0025p2"
     CDS             complement(16183..16857)
                     /locus_tag="HS273_RS00100"
                     /old_locus_tag="SUJ_0025p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16914..17090)
                     /locus_tag="HS273_RS00105"
                     /old_locus_tag="SUJ_0026p2"
                     /pseudo=""
     CDS             complement(<16914..17090)
                     /locus_tag="HS273_RS00105"
                     /old_locus_tag="SUJ_0026p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17104..17841)
                     /locus_tag="HS273_RS00110"
                     /old_locus_tag="SUJ_0027p2"
     CDS             complement(17104..17841)
                     /locus_tag="HS273_RS00110"
                     /old_locus_tag="SUJ_0027p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17834..18763)
                     /locus_tag="HS273_RS00115"
                     /old_locus_tag="SUJ_0028p2"
     CDS             complement(17834..18763)
                     /locus_tag="HS273_RS00115"
                     /old_locus_tag="SUJ_0028p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18879..19760)
                     /locus_tag="HS273_RS00120"
                     /old_locus_tag="SUJ_0029p2"
                     /pseudo=""
     CDS             complement(18879..19760)
                     /locus_tag="HS273_RS00120"
                     /old_locus_tag="SUJ_0029p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19757..>20134)
                     /locus_tag="HS273_RS00125"
                     /old_locus_tag="SUJ_0030p2"
                     /pseudo=""
     CDS             complement(19757..>20134)
                     /locus_tag="HS273_RS00125"
                     /old_locus_tag="SUJ_0030p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20192..20866)
                     /locus_tag="HS273_RS00130"
                     /old_locus_tag="SUJ_0031p2"
     CDS             complement(20192..20866)
                     /locus_tag="HS273_RS00130"
                     /old_locus_tag="SUJ_0031p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21340..22806
                     /gene="msr(A)"
                     /locus_tag="HS273_RS00135"
                     /old_locus_tag="SUJ_0032p2"
     ARG             21341..22803
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22905..23804
                     /locus_tag="HS273_RS00140"
                     /old_locus_tag="SUJ_0033p2"
     CDS             22905..23804
                     /locus_tag="HS273_RS00140"
                     /old_locus_tag="SUJ_0033p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24290..24898
                     /locus_tag="HS273_RS00145"
                     /old_locus_tag="SUJ_0034p2"
     CDS             24290..24898
                     /locus_tag="HS273_RS00145"
                     /old_locus_tag="SUJ_0034p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25144..25482
                     /locus_tag="HS273_RS00150"
                     /old_locus_tag="SUJ_0035p2"
     CDS             25144..25482
                     /locus_tag="HS273_RS00150"
                     /old_locus_tag="SUJ_0035p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25487..25672
                     /locus_tag="HS273_RS00155"
                     /old_locus_tag="SUJ_0036p2"
     CDS             25487..25672
                     /locus_tag="HS273_RS00155"
                     /old_locus_tag="SUJ_0036p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25899..26642)
                     /locus_tag="HS273_RS00160"
                     /old_locus_tag="SUJ_0037p2"
     CDS             complement(25899..26642)
                     /locus_tag="HS273_RS00160"
                     /old_locus_tag="SUJ_0037p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22906..23801
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21341..22806
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22906..23804
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(14881..15398)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15705..16006)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7713..8557)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1349..1496
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..983
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.492"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1115..1284
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25900..26642)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa gggttagaaa acgatggtct actcattcaa aaacgacgtg
      301 gtttaaataa accaaatatt ctatatttaa tgaaacctat tgtcacagaa cgtgatattt
      361 acaaaataga aaaagaagaa aacgatgttg aaccttacgg cgagaaggaa gttcgaaaat
      421 cgaacgtcca gaagttcgaa aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag
      481 ttcgaaaatc gaacactaat gatactgact ttaatgacat tgactttaat gatactgaga
      541 ataatgatat gaatgacttg aatgatataa agtacaaaaa tgaaattagt aatcattcaa
      601 atcattcaaa tcaatttaca cataattttg atgataaaga aatgctattg caagaattcc
      661 cagaacaact aactaattat ttattaaaat atgattatag agatttagaa atcataaagg
      721 ctgttattct taaagcaaaa aaatcattta attcaaggca tgaagatatg cattacatgt
      781 tagaggacat tgaggatgaa atattaactt ctttaaaaag acttaaaaaa gctatacatg
      841 ataggggagt taaaggccaa aaggaaacaa tcaagtcaat gcaagcttat ttaatgcaaa
      901 caattctaac tgaacttgaa gaaacacatg ccctttatat gcgccgtaaa aacatgaaac
      961 aatataatat ctttaatcaa taattcaaat gattttataa cactcgaaga gacatcaaaa
     1021 tattccgtta aatcatctga ctttttaact gatgacgacg aaaaaaatca agaaattgta
     1081 agtgatttag aaaaaggttt gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa
     1141 caaaagcata aaattttaaa cttagacgat gccgaagatg gtaatttgat taatacaagt
     1201 gatgaagata aaacgacaga cgaagaaaaa aagcacattc aattaccgca atttggaatt
     1261 tcgaaaagca aaattattat ttaagacatt agtgataact gatgtctttt tttattgttt
     1321 ttctgtaaaa aagtgctgtc ttatttttgt gacaaatgct gtatgtagtg tcacaaaagt
     1381 gtgacactac agctttgtat gatatcactt taaaataact taaaaccctt ggaatgtctg
     1441 gccttgccag atctatcatt tttgaatgat agcaaatttc ccttatgctc ttacggagat
     1501 tttagagtta aattaaaatt tctaagtttt tgataagaaa agccctgcag gaatttagaa
     1561 aaacatgggg aagttttaaa gtattttatg ctaattttta aatttgcatg taaatgggca
     1621 gtatctaaaa aattagtcac tgattttgct gaaatttttg tttgtgaaat tagcatatat
     1681 ttatttggct catatttgcg ttttaagaga ctgtatagat ttttaagtac aaaacctata
     1741 tgatttgcct ctaagtcttc aaaatgcctc ttaaaatcca aaataaaagt gtttaatatt
     1801 gtaataagga ttgctatttt tataaaagga gagatatcat gaagattaaa actttcgcta
     1861 cttttactca tcgtcaatta gataaacaag ttaataggtt tttaaagaat gatattcatg
     1921 tattagaaat tcaaacacac agtaattggt tatatatttc agctattgtt ttttatgagg
     1981 ataaataagg aacatcgtat ttatgccgaa aaaatttatt gatgttgaga agaaccctta
     2041 actaaacttg cagacgaatg tcggcatagc gtgagctatt aagccgacca ttcgacaagt
     2101 tttgggattg ttaagggttc cgaggctcaa cgtcaataaa acaattggaa taaaatcaac
     2161 ctacagagca tccagctgca aatgcagttc cgcaaactgc ttcacataca ccgccggcta
     2221 ttggatttac gattgcccat actccacagt agtgagcaca tgcataaagt ccagccatac
     2281 tacaagcgaa tgctttgccg ttccatttga atcctgcata tgttaccggt ctgtttttat
     2341 caactttttc agccttatat tcaacgtaat ttttgttaat aagtattttt ccctctttgt
     2401 tttcagtcat acttcttttt tcggcaatga attttgtgat ttttttgttg tagttatcat
     2461 atattgtttc agaaactaca atttcttttg ttttttcatt tttataagcg ttattagcta
     2521 tgtagccata tgcattttta tcatttgctt ctgtagctag atattttaat ttagaatttt
     2581 tgtcttctag ctttattttt ttaaatcctt cttttttcat ttgcttttcg aatttttgca
     2641 tatcttcatt tttattttgc aattgttcta gaaaacttat ttctttcttg gtcatttgtg
     2701 atacttcgat gtttttgctt ttcaattttt ctttttgatt ttctagtaaa gaactttttt
     2761 gttcttcatt tgcgtaagca ttagaaaaat tcgcgctaaa taccagtagg aacaaggaaa
     2821 ttattgaaaa taattttata attttcattt gatacctcca agataataag atattttaat
     2881 tgtataagta agcgctttat aaaatcaata tttattttaa tatatttata aacatatttt
     2941 tgaaaggagt ctattttatg aatgaaaatt tagaaaaata tataaaaagt ttgccacttt
     3001 taggtttgtt aattagtatt ttgttaattg ttttattctt ttttatttta gatgttgatg
     3061 aagatttatt cgtggttttt ttatactgtt tattgccttt gatagttaat ttgtctattt
     3121 atggttttta tgtttttgtt aaaagaaagt aagattatga ataattttgt ttttaatttg
     3181 tatgctttga gggggttgga aaacggtagg tgtatagatt agatttcttg tttttttgaa
     3241 acgagtgtga acgagtttct tcttgtcttg atttttgata aaaacgccct acaggaattt
     3301 agaaaaacgt ggggaagttt taaagaattt tatgctaatt tttaatttgc atgtaaatgg
     3361 gcagtgtcta aaaatagtta ttgtttttgc tcaaattttt gtttttgaaa atagcatata
     3421 tttatttggc tcatatttgc gttttaaaag catatataag ttttagatat aaaactatat
     3481 gaatcacccc taaatcttta aaatgccctc ttaaaattca aaataagggc ataaaaaata
     3541 aaagctaccc cagataaagt gaggtagctt tttctttcat acggtctatt tatttttctt
     3601 tcgacgccgt atcgtcgatg taattcaaaa aagttatggg ctataaatct acatcacttt
     3661 ttcaagaatg tagtagcaat attcaacgca aattaatttt tataactgct cggaatatct
     3721 caagccgttt ctttaatttt gaaataaaaa aatcgacgaa ggtcgattac gtttttgcac
     3781 atgtcgattt atccgacgta taagtgcgcc cttacgggat ttaactagat tataacgacg
     3841 aattttagac ctgtaaagca ataacaatta ggtctaccag gtagataaag tgtacaaagt
     3901 agaaccgaaa aagttattta ttttgaagat ttttcgtaga tataatttgc taataaactt
     3961 cctaaaactg aataaagaaa aatagttaaa ctcatgtaat cactccataa ttctgaagtg
     4021 tctccatgtc tacgcataga cacgcattta tgccgaaaaa atttattgat gttgagaaga
     4081 acccttaact aaacttgcag acgaatgtcg gcatagcgtg agctattaag ccgaccattc
     4141 gacaagtttt gggattgtta agggttccga ggctcaacgt caataaagca attggaataa
     4201 agcacctatg attatttaaa aatataagtt ataatacatt caaaaatatt tttgaatgag
     4261 gtgtattatg attcaaacgg ttgttgctgc tgctgttctt tatattgcta cagcagttga
     4321 tttattagta attttattaa tattttttgc tagagcaaag actagaaaag aatatagaga
     4381 tatttatgtt ggtcaatatt tagggtctat tattttaata ttagttagtt tgtttttagc
     4441 ttttgtatta aattatgttc cagaaaagtg gatattaggt ttattgggtt taataccaat
     4501 ttatcttgga attaaagtgg ctatttatga tgattgtgaa ggagaaaaga gagctaaaaa
     4561 agaattgaat gaaaaaggat tgtctaaatt agttggtacg gttgcaattg ttacgatagc
     4621 aagttgtggc gccgataata ttggtttatt tgttccgtat tttgtgacat taagtgttac
     4681 taatttatta cttactctgt ttgtcttttt aattttaatt ttcttcttgg tgtttactgc
     4741 acaaaaatta gctaatattc caggaattgg agaaattgtt gagaaattta gtcgttggat
     4801 tatggctatt atttatatag ctttaggttt atttattatt attgaaaatg acactattca
     4861 aacaatttta ggatttatat tttaatttag ggtgtgattt tatatgagtt atgaaaatac
     4921 ttgtgatgtg atctgtgtac atgaggataa agttaacaat gctttaagtt ttttagaaga
     4981 tgataaatct aagaaattac ttaacatttt agaaaaaatt tgtgatgaga agaaattgaa
     5041 aatcatatta tctttgatta aagaagatga gttgtgtgtt tgtgatattt ctttgatatt
     5101 gaaaatgagt gttgcttcaa cttcacatca tttaaggctt ttatataaaa atgaggtact
     5161 tgatttttat aaagatggaa agatggcata ttattttatt aaagacgatg aaataagaga
     5221 gtttttctct aaaaatcatg agggtttttg aaacgagttt cttcttgtct tgatactata
     5281 aaaaacaaag ttatataaca taagacgact tatcggaagt agatatgctt gtatattcac
     5341 agatggtata ataatagagt cgcctatctc tcaggcgtca attgacgaag agaggaggtg
     5401 cattactttg ctaatcattt tcgttcacat catagcacca gtcatcagtg gctgtgctgt
     5461 tgcgtattat acttattggc ttagtaaacg caacaaataa ttaataggcg actttataag
     5521 ccagcatcga aaaaatcccc acactactgc aatagtgtgg ggattggtgc attaattgtt
     5581 aatcattttc gttatataaa ttataacact ggttagtaga gaaatgcaaa atgattgaat
     5641 taatagtaaa tgtattaatg aatactcaca cttatacttt taaaatagtt cttcctaaat
     5701 gttgtccttt taaaagctga tctatcgttt tatagaattc ttcaaatcca atttcattgt
     5761 atagaagtga atttcctata ttccattcat ttgctaactt actccatata tcttcacgga
     5821 tattatgatc aacatataca gaatcaatgc caattaattt aatacctcta agaataaacg
     5881 gtaatatatt agcgttaagt gaatttcctg ctacatttcc acatacagta gcaacacctt
     5941 gataatttag acgttttaaa ccgtataatg ttacattact ccccactgta tctaagaaat
     6001 aatcaaaaat acctttttta agcggtttat tatcatcttc aattattatt acttgttttg
     6061 cacctaattt ttttgcgatt tctatttgct tttcttttct tacgatagca gtgatatttt
     6121 catatccaat tttatgtaaa atttgtatag caacactgcc cacaccacct gtagccccag
     6181 acactaaaat ttcaggttgt gatttgatat tcattccata tttttctagt tcaaaaattg
     6241 ataatgctgc cgtaaaaccg gctgtgccat ataccataga ctctttaata gacatttctt
     6301 ggggaatagg aacaatccac tctccaggca cttgtgcata ttctgaaaat ccacctgtat
     6361 gtgtcacgcc aacatcataa ccagtaacta atacattatc gccttcttta aacttatcat
     6421 tcgaacttga ttcaacaata cctgcaaaat ctataccagg aatcatagga taatctctaa
     6481 ttacaccgcc tttatattgt aaagctagca tatccttata atttattgaa gagtatacca
     6541 cttttactaa tacatcaccc ttcgataaat gagattcatc aactttttct actttataac
     6601 taacatttga tgcacttttt ctcactacta ccgcattgaa catttattag ccttctttca
     6661 caattgtttt gtagaagtat gtttttgttg caaaactatt ttcctacaaa acttatcatg
     6721 atatgataag cgagtcaata ctaatgattt aagagaggtt ttagttgtgg aattagataa
     6781 ttgtataaat tatttgttga gtacttctca gaatagagtt tttaaacatt ttaaaagttt
     6841 attaagtccc tataatatta ctccagcaga atatggtgtt ttgaattgct tgattaatag
     6901 taatttgaat acacctaaag cgattggtaa tactttaaat ttagaacctt caacaatatc
     6961 tggaatatta gataagatgt ccaaaaagga tctaataaca cgtcaaactg ataatgaaaa
     7021 tagaagaact gtgctaataa acagtacaaa taaagcaaaa gacttatggc caacattaga
     7081 aaagaaagcc tatcaactta ataatcatta cttcgctaat ttaactaatg aagaaactgt
     7141 agtgtttaaa aagatattac taaagataaa taaaactacg ttttaatttt tacgttataa
     7201 aaaagttgaa gtgcgaatta taatcgagta aatataaatg atagcttagc ttaattatat
     7261 attaaagcca actatacttt tattcccgaa aaacctacta tccaaatttc taagatactt
     7321 tagcctctat aataaacata ttgtaatata atttatgtat tatttaggtt taccctaatc
     7381 gaacaataaa aaatacttgt aaaatgctat tgtcactttg cttgatatat gagaattatt
     7441 taaccttata aatgagaaaa aagcaacgca ctttaaataa gatacgttgc tttttcgatt
     7501 gatgaacacc tataattaaa ctattcatct attatttatg attttttgta tatacaatat
     7561 ttctagtttg ttaaagagaa ttaagaaaat aaatctcgaa aataataaag ggaaaatcag
     7621 tttttgatat caaaattata catgtcaacg ataatacaaa atataataca aactataaga
     7681 tgttatcagt atttattatg catttagaat attaaaattc cttcattaca ctcttggcgg
     7741 tttcacttat caacttatca tttggcttat cacttttatt gtctttattc gtaaaaatga
     7801 ctaaaacaat aggttcagat tggcccttag gataaacaaa agcaacatca tttctagaag
     7861 catatgttat tgcttgacca cttttatcag caaccttata gtcttttgga acaccatctt
     7921 taattaaagt gtctccgttt ttattattaa acattaaatc aagtaagaaa tttttatttt
     7981 ttttgcttaa ttttccattt gcgataagtt tatttaaagt cttgccgaaa gcagcaggcg
     8041 ttgaagtatc ttttttgctc tttggtgaat agtaatttaa ttctatctca tatctaactg
     8101 gatttgttac tttatctcct agttctttta gacgttgttt aacttttttg attccaccga
     8161 tttcttttat aattttattg tttgctgtat tatcactata tgtcattgaa gcctcaataa
     8221 gttcttttaa agtgatatct tttcctacat atttttctaa aataggagaa taagcaacta
     8281 tatcatcttt gttaatatgt acttttttat ttaacttatt ataaggtact tgttctaaca
     8341 aaatagcact atttatcgct tttgaagtcg aagcataggc aaatctctta tctgaattaa
     8401 attttacttc cttaccactt ttagtattta aagcataaac accaatatga gcattatatt
     8461 ttttttctaa atcatttaac tctttggcat gtgaactgtt tgaattacat gcacttaaaa
     8521 ctaaagcaat tacaattaaa aatattaact ttttcaaaat aaaccctccg atattacagt
     8581 tgtaattttt ataaatcaat aatattacaa ttgtaatatt gatgtcaatt gtttattata
     8641 aatatttgaa agaaggtgtc aaaatggcta aattactaat aatgagcgta gtaagctttt
     8701 gttttatatt tctattgtta gtatttttta ggtacatatt aaaacgctat tttaattata
     8761 gtttaaatta taaagtttgg tatctaacta tgcttgctgg attaattcct tttatcccaa
     8821 ttaaattctc ttttataaaa tttaataatg tgaataatca agcgcccaca gttgaaagta
     8881 agtcacacga tttgaaccat aacataaata ccaccaaacc tattcaagag ttcacaacag
     8941 atatccataa gtttaattgg gattcaattg ataatatctg cacagttatt tggatagttt
     9001 tagttattat tttaagtttt aaatttttga aagccttatt atatcttaaa tatttaaaga
     9061 aacagtcact ttatctaaac gaaaatgaaa aaaataaaat agatacgata cttttcaacc
     9121 atcaatataa aaaaaatatt gtgattcgaa aagcagaggc tattcaatct ccaataactt
     9181 tttggtatgg gaaatatatt attttgattc ctagttcata ttttaaaagt gtaattgata
     9241 aaagactaaa atatataata ctgcatgaat atgctcatgc taaaaataga gatactttac
     9301 atttaattat ctttaatatc ttctctatta ttatgagtta caatccatta gtacatattg
     9361 taaaaagaaa gataattcat gacaatgaag tagaagccga tagatttgtc cttaataata
     9421 ttaacaaaaa tgaatttaaa acttatgcgg aatctattat ggactccgta ttaaaaaccc
     9481 cattttccaa caaaaatata ttaagccatt catttaatgg taaaaaatca ttactcaaaa
     9541 gtagattaat taatataaaa gaagccgatc tgaaaaagca gtcaaaatta attctaattt
     9601 ttatttgtat ttttactttt tttatcatga taattcaaag ccagttttta atggggcaat
     9661 ccttaactga ttataattat aaaaagccct tacaaagcga ttaccaaatt ttagatgaaa
     9721 gtaaaaattt tggttcaaat agtggatctt tcgttatgta cagcatgaag aaagacaaat
     9781 actatattta taatgaaaaa gaaagtagaa aaagatattc tcctgattca acttacaaaa
     9841 tttatttagc actgtttgga cttgaccgtc atattataag tgataaaaat tcacgtatgt
     9901 catggaatca taaacattat cttttcgagt cttggaataa ggaacaagat ttaaatacag
     9961 caatgcaaaa ttcagttaat tggtacttcg aacgtattag taatcaaata ccaaagaact
    10021 atactgcggc tcaactcaag caattaaatt atggtaatga aaatttggga agttataaaa
    10081 gctattggat ggaagatagt ttgaaaatat ctaatcttga acaagtaata gtttttaaaa
    10141 atatgatgga acaaaataac cattttagta aaaaagcaaa gaatcaatta tcttcttcat
    10201 tattgattaa gaaaaatgaa aagtatgaac tgtatgggaa aacaggtaca ggtatagtaa
    10261 acgggaagta taataatggg tggtttgtag gttacgtaat tacaaatcat gataagtatt
    10321 attttgctac acatttatca gatggaaacc cgtctgggaa aaatgctgaa ttaataagtg
    10381 aaaaaatatt aaaaggaatg ggtgttttaa atgaccaata agcaagttga aatatctatg
    10441 gctgaatggg atgttatgaa tataatatgg gataaaaaat cagtatcagc taatgaaatt
    10501 gtagttgaaa ttcaaaaata taaagaagtt agtgataaaa cgattagaac attaatcaca
    10561 agactatata aaaaagagat tataaaacga tacaaatcag aaaatattta tttttactca
    10621 tcaaatatta aagaagacga tattaaaatg aaaactgcta aaacctttct taataaactg
    10681 tatggagggg atatgaaaag tttagtgctg aattttgcga aaaatgaaga attaaataac
    10741 aaagaaattg aagaattgcg agacatttta aatgatatta gtaaaaagta attagaggta
    10801 tgtttcaaac ataatacata tgtaaaccat acttgactct tattaaatta gttttgttaa
    10861 tgacatttaa aatatattat taaagatgag agtgtccaga aaataaccat tttctgtaca
    10921 ctcttgtttt ttgtctaaat aagtaagtat tacatagaat tatgtgttca aaaacccaac
    10981 aaaaaatcta tgttcacaaa agacctcgta atcaagttat ggtacactaa aggtgtatat
    11041 aggaggtctg tattttgaaa ataggttatg caagagtttc aactggatta caaaatttga
    11101 atttacagga ggatcgatta aatacatatg gttgtgaaaa gatatttaat gaccatatga
    11161 gtggttcaaa aagtaagcga cctggtttag ataaagcaat tgaatttgcg aggtcaggag
    11221 atacgattgt tgtttggaga ttagatagac taggacggaa catggaggat ttaatcacgt
    11281 tagttaatga acttaacgaa cgaggtgtga gttttcatag tttagaagaa aatataacga
    11341 tggataaatc aagttctaca ggacaattat tatttcattt attcgcagca tttgcagagt
    11401 ttgaacgtaa tttaatttta gagcgatcat cagccggtcg aattgcagca cgtgctagag
    11461 gccgatatgg aggtagacct gaaaaattaa ataaacaaga tttaaactta cttaagacac
    11521 tttatgataa tggtacgcca attaaaacaa ttgcagagca gtggcaagtt tcacgtacaa
    11581 ctatttatcg ttatctcaat aaattagagg caaaagagaa taaaaacaag tagagcaact
    11641 aatctagctt actataatga atctactaaa taattttata tatcattaac atacaaagac
    11701 tttgattcaa tgtcactcga tgtaaaagag acgttctgac agcgtctaaa atctcataat
    11761 attttcctgt tatgagattt taataataac acaagaaaaa agcgtacaaa ttcgtacgct
    11821 tttttaatat aatacctgtt tcactaatga acgttttaag tatcttcatc attaactgaa
    11881 actacagtaa taatactcgt caacaatatt agtatagtta aaatagaaag acttaggact
    11941 ggcataaccg aactaaaatt atatttgaaa tataaaagtg ctaatgaaga gagaaatgta
    12001 aaaataataa ataccaaaga ccatttttct aatttattca ttggcttcac ctctttgaac
    12061 ttttatataa tcataggaga tatttttact acgatttata aaaaataaga agataatcat
    12121 tattaaagaa acgattaata taatgttgaa tcctatagta tcacctaatt cgtttacacc
    12181 tttgcctaat atcggagata caaagctttg tattaataat gaaagagatg cccatatagt
    12241 aaatgaggtt ctgttgcaaa gttgaattta tagtataatt ttaacaaaaa ggagtcttct
    12301 gtatgaacta tttcagatat aaacaattta acaaggatgt tatcactgta gctgttggct
    12361 actatctaag atatgcattg agttatcgtg atatatctga aatattaaga gaacgtggtg
    12421 taaacgttca tcattcaacg atctaccgtt gggttcaaga atatgcccca attttatatc
    12481 aaatttggaa gaaaaagcat aaaaaagctt attacaaatg gcgtattgat gagacgtata
    12541 tcaaaataaa aggaaaatgg agctatttat atcgtgccat tgatacagag ggacatacat
    12601 tagatatttg gttgcgtaag caacgagata atcattcagc atatgcgttt atcaaacgtc
    12661 tcattaaaca atttggtaaa cctcaaaagg taattacaga tcaggcacct tcaacgaagg
    12721 tagcaatggt taaagtaatt aaagctttta aacttaaacc tgactgccat tgtacatcga
    12781 aatatctgaa taacctcatt gagcaagatc accgtcatat taaagtaaga aagacaaggt
    12841 atcaaagtat caatacagca aagaatactt taaaaggtat tgagtgtatt tacgctctat
    12901 ataaaaagaa ccgcaggtct cttcagatct acggattttc gccatgccac gaaattagca
    12961 tcatgctagc aagttaagcg aacactgaca tgataaatta gtggttagct atattttttt
    13021 actttgcaac agaaccagca tttgttttaa tatttgttcc aaagagccat catggctttg
    13081 acagagctct tcttctatgc aaatgctttt aatccgatcc acacgaaaat tcctatattc
    13141 atttcttagc ctgcaaaacc gattaagtac cagttctgtt cataaaaccc cagtgatata
    13201 ggctctatca ttctgctttc cggttcttgc cctcctgatg caggatattg aattgatatt
    13261 acccttttat tgcagattgc agtctgaatt gctgcaataa cgttatccgc caatgtattt
    13321 ttctgtccag atgtgctgta cacgttaata ctgttctcca actcctgtgc atagtttttt
    13381 tcaccatgct tcaaaataga tttgatttta tacatagctg aatcaaaatc ctttataaat
    13441 gattcatctc catggcaatt taaaaatttc cctgctgtaa tcaatgcacc cacttccgcc
    13501 gctgtaaaca ttaccggcag aagtaggaag ccctctacaa gaaaatatcc ttttccggcc
    13561 tcagatccaa ttggtattcc ggcttcttca agtgtccgga tatctctgta aactgtcctt
    13621 aagcttatat taaatcgctg tgcaatttct ttggcaggaa ttattttttt gattgcagct
    13681 gaataagaat agaggttact ctgttaatcc tgttcaaatt ttattcctcc tctgtgactt
    13741 ccataaaaag tatatcctat gcgttcttaa gctagctgct gttagtgctt ctcattgcac
    13801 cctggttata aaagccatac tcacaaacct cttcaccaaa actctttaca tctctaatat
    13861 agaactctat ctagcgaact tttagaaaag atataaaaca tcagagtatg gacagttgcg
    13921 gatgtacttc agaaaagatt agatgtctaa aaagcttgta gttaaagctt tttagacatc
    13981 taaatctagg tactaaaaca attcatccag taaaatataa tattttattt tctcccaatc
    14041 aggcttgatc cccagtaagt caaaaaatag ctcgacatac tgttcttccc cgatatcctc
    14101 cctgatcgac cggacgcaga aggcaatgtc ataccacttg tccgccctgc cgcttctccc
    14161 aagatcaata aagccactta ctttgccatc tttcacaaag atgttgctgt ctcccaggtc
    14221 gccgtgggaa aagacaagtt cctcttcggg cttttccgtc tttaaaaaat catacagctc
    14281 gcgcggatct ttaaatggag tgtcttcttc ccagttttcg caatccacat cggccagatc
    14341 gttattcagt aagtaatcca attcggctaa gcggctgtct aagctattcg tatagggaca
    14401 atccgatatg tcgatggagt gaaagagcct gatgcactcc gcatacagct cgataatctt
    14461 ttcagggctt tgttcatctt catactcttc cgagcaaagg acgccatcgg cctcactcat
    14521 gagcagattg ctccagccat catgccgttc aaagtgcagg acctttggaa caggcagctt
    14581 tccttccagc catagcatca tgtccttttc ccgttccaca tcataggtgg tccctttata
    14641 ccggctgtcc gtcattttta aatataggtt ttcattttct cccaccagct tatatacctt
    14701 agcaggagac attccttccg tatcttttac gcagcggtat ttttcgatca gttttttcaa
    14761 ttccggtgat attctcattt tagccattta ttatttcctt cctcttttct acagtattta
    14821 aagatacccc aagaagctaa ttataacaag acgaactcca attcactgtt ccttgcattc
    14881 taaaacctta aataccagaa aacagctttt tcaaagttgg cgtataacat agtatcgacg
    14941 gagccgattt tgaaaccaca attatgatag aatttacaag ctataaggtt attgtcctgg
    15001 gtttcaagca ttagtccatg caagttttta tgctttgccc attctataga tatattgata
    15061 agcgcgctgc ctatgccttg ccccctgaaa tccttacata cggcgatatc ttctatataa
    15121 gcgtaccggt tccaattttt tcgcagttta acttttccga cgcatttatc gtcttggtag
    15181 taaagatata ttatcttatc agtattgtca atatattcaa ggcaatctgc ctcctcatcc
    15241 tcttcatcct cttcgtcttg gtagcttttt aaatatggcg cttcatagag taattctgta
    15301 aaggtccaat tctcgttttc atacctcggt ataatcttac ctatcacctc aaatggttcg
    15361 ctgggtttat cgatatcttt caggtgccct gctttcattt ctgtaatcac tgttcccgcc
    15421 tctcttctat atcagcggca tatgtgctat ccaggcagcc ggttttacca gtgtattttt
    15481 tatacatgtc cctggtatat tttgttatat tcctatcata ctccggatag gcataatgaa
    15541 gcctttccgc cacctcaccg gataccgccc tgaacaattg atggcataga aataatgctt
    15601 cccatatgtt ttcataggaa tccatccggt aggtggacaa aagtttctcc cacaaatcct
    15661 cggatatata cctttcaata aacttatagt tcttgcctac acttcattta aagcctgttt
    15721 cgatgccgac cttccatgat atcattctca gcagctcatg gcgaacaatc tgattaaaat
    15781 gatcaatagc aaataaaatt tccttacggc acaatccttt aataacataa ggtgttacat
    15841 tccaaaattc attgcagcaa tcatcatact cccttgcgct tggctttctt acatgataat
    15901 ctatatcagt cggaactatg tcccttttaa ttctacaatc tttatcaatt agaaccttta
    15961 ttaatttatc gccctttagg taattatcta actcttccaa gggcaataag gtaagatcaa
    16021 ttttattgta atcatcaaat agctataata gatttagagg taaagaaatt aaatacattg
    16081 aagagcagaa agattttaca aaagagtatt ttaataaaaa tgatggttct gttgcaaagt
    16141 aaaaaatata gctaatcact aatatatcat gtcagtgttc gtttaacttg ctagcatgat
    16201 gctaatttcg tggcatggcg aaaatccgta gatctgaaga gacctgcggt tctttttata
    16261 tagagcgtaa atacactcaa taccttttaa agtattcttt gctgtattga tactttgata
    16321 ccttgtcttt cttactttaa tatgacggtg atcttgctca atgaggttat tcagatattt
    16381 cgatgtacaa tggcagtcag gtttaagttt aaaagcttta attactttaa ccattgctac
    16441 cttcgttgaa ggtgcctgat ctgtaattac cttttgaggt ttaccaaatt gtttaatgag
    16501 acgtttgata aacgcatatg ctgaatgatt atctcgttgc ttacgcaacc aaatatctaa
    16561 tgtatgtccc tctgtatcaa tggcacgata taaatagctc cattttcctt ttattttgat
    16621 atacgtctca tcaatacgcc atttgtaata agctttttta tgctttttct tccaaatttg
    16681 atataaaatt ggggcatatt cttgaaccca acggtagatc gttgaatgat gaacgtttac
    16741 accacgttct cttaatattt cagatatatc acgatagctc aatgcatatc ttagatagta
    16801 gccaacggct acagtgataa catccttgtt aaattgttta tatctgaaat agttcataca
    16861 gaagactcct ttttgttaaa attatattat aaattcaact ttgcaacaga acctcctaac
    16921 tgtattacca ccttaaaagt agttgcagac gcacttccta aatcgtcagc agtgtttaac
    16981 cacatatcat caacaataat catatgacct gttgatgata ctggagcaaa ttctgtcaac
    17041 ccttcaacta cacctaaaat aaatgcttta atctgctcta taaaacccat ttttctcctc
    17101 cttttaactt atatcagttt ttttaaagta tgagaataat ataattacac tgaatataga
    17161 tgtaacaatt atgataatta aagataatag aaatggataa gtattaggta atgttcctct
    17221 agatatgtct ccaactgcag cccaaggaaa taatcctcta tgttcagaat tagcagtcat
    17281 taaatttatc aaagtaatta ttatggttaa aacaattgtg ggaacataat ttttaaaata
    17341 tatcgacaaa ataattattg gtggagataa tatccataat aacactccgc caataacaaa
    17401 tgtaaagaat gaatcaatta ttaaactctg gcttaaccct tgaaaatgca atagcatacc
    17461 tagcattaaa gttagcaacc atgcaataac agatagtgtt tgaatccaca agaataataa
    17521 tattatttta cttactaaaa aactttctct agatataggt ataattaata agttttttaa
    17581 agtatcttct atatattctc ttccaaacaa ataggctatt ataaccccat atagaggagg
    17641 tccaataatt agcatatgat ataaactgac ttcttcaaat aactgtttaa atacaatatt
    17701 aggagtcggt actttcgtcc gcatactaat aaaagaagct acaaccacca taaaaggtgc
    17761 tacgcatgta cctaaaatac ttattagaaa catatatgat ctttttaact taataaattc
    17821 tgtacggagt agattatcca attgtgccac ctcctactaa gtcttcgaaa taagtttcta
    17881 gattatcttc tatcactctc atctggaaaa catcaatatt gtttaatact aataatctat
    17941 taatttcttg ttgtctatca atatgtgaat aaattttaaa ttcgccattt tctttaattt
    18001 tatagtcata aattccgaag ttagtttcca acaaacatgc aactttttct tcatctgata
    18061 ctgatatact tataaattgt ctgttctttt tttttaaatc ttcatacata atttcttcta
    18121 acaaaactcc gttatgaata atacccacct tgtctactaa ctgctctatt tctgacaata
    18181 tatgacttga aattaaaatg gttatatttc tagattgagc cagatcctta atcaactttc
    18241 taatttcttt tatgccaata ggatctaatc cattcgtcgg ctcatcaagt atcaataatt
    18301 cgggattgtg caataaagct ctcgcaatcc ctaaacgttg cttcatacct aaagaataat
    18361 ttttaaacaa ttttactttt tcagaagcta gtcctactat ttctaacact tcttcaattg
    18421 cattttcttt ttgtatacct aatattttag catttatagt taagttctct ttagctgtca
    18481 aattactata aaaacctggc gtttcaacca tagcaccaat attttttaaa atttcagttt
    18541 tattactttc gaactctttt tcaaatattt taatattacc tttcgtaggt ttaattaagc
    18601 ctaaaagcat tcttatagta gttgttttgc ctgcaccatt tcttcctaaa aaaccataaa
    18661 tttgtccact ttcaacagtt atactcaaat tattaactgc tatctgactt ccatattgct
    18721 ttgttaagtt atttatttca attatattat tcaaattttt cacctctggc acctttctta
    18781 gtttgttgtt acctttatct tacgcgcgat tagaaaaggc tgcctttatc tattcttaca
    18841 aaaacagccg ctaatcttac aaaaatgaaa gattggagtt atttaaattg aatggtgaat
    18901 attgaaccat cgtttaatgt agatgtagca cttactttat ggcctaagcg ctttgagatt
    18961 gtgctgacaa tatataaacc aataccgctt gatttctcac ttattctacc gttatagccc
    19021 gagaaacctt tatcaaagat tttcggtaaa tcactcgcat taatgccgat accgttatct
    19081 cggattgata atttctttgt attttcgtca aacgtaatcc acacatcttt gccacgtgca
    19141 tattttaatg cattgtttaa tatttgctca atcataattg atgcccattt ggcatctgtt
    19201 aatataaccg cttcactttt ctcataatgc aactttgttt gatgatgaat aaactgtatc
    19261 gcataacgtt taatcagtgg tcgaattaat tcatctacac tcacttccat aaagaccatg
    19321 tatgtctttt ggttcatgag tttcaaatag ttcagtgcaa gattcgtgta attatcaatt
    19381 tgtaagactt cattacgcac gttagaaatc acgtgttcat caggatcttc aagcagtaac
    19441 tttgatgctg taatcggtgt cttgatttga tgcacccaca ttaaaaaata tgactctaac
    19501 tcactttggt agttaataaa gtcattacga agtttatggt tttcgattct taaatcttcg
    19561 ttctgttcct gtagtgttta ttctttttta aagttcatgt aatggatacc ccagtaaatc
    19621 attgaaacaa acaatacaat acctagacca atcatatatg cttgcatcgg cacattatac
    19681 atgaataata taaagtagaa taaagcacaa gtaaggatga caatataaat ttcacgttgg
    19741 attgatttca agaaattcat acgtcaccta cacgatatcc gacatttttc ttcgtttcga
    19801 taaaatctgt aagtcctagt ttttgtagct ttttgcgtaa acgtgtaatg ttgacagcaa
    19861 gcgtattgtc atcaatgaag tgttctgatt cccagcattt ttcgattaac gcattacgac
    19921 tgacgaattt gcccttgttc tggaataagc tatgcatgat ttgcaattca gtgtgtgtca
    19981 ggtctatggt ttcttcatta aatttaagct ttgctgcatc aagtagtaac tcgcaatcat
    20041 ctactgttaa attattaact tgagtggtga aatcatacgt gcggcgtaat agtgcttgaa
    20101 tcttagtaat tgtaacagtc atattaaatg gctggttctg ttgcaaagta aaaaatatag
    20161 ctaatcacta atatatcatg tcagtgttcg tttaacttgc tagcatgatg ctaatttcgt
    20221 ggcatgggga aaatccgtag atctgaagag acctacggtt ctttttatat agagcgtaaa
    20281 tacattcaat accttttaaa gtattctttg ccgtattgat actttgatat cttgtctttc
    20341 ttactttaat atgacggtga tcttgctcaa tgaggttatt cagatatttc gatgtacaat
    20401 gacagtcagg tttaagttta aaagctttaa ttattttagc cattgctgcc ttcgttgaag
    20461 gtgcctgatc tgtaactacc ttttgaggct taccaaattg tttaatgaga cgtttgataa
    20521 acgcatatgc tgaatgatta tctcgttgct tacgcaacca aatatctaat gtatgtccct
    20581 ctgtatcaat ggcacgatat aaatagctcc attttccttt tattttgata tacgtctcat
    20641 caatacgcca tttgtaataa gcttttttat gctttttctt ccaaatttga tataaaattg
    20701 gggcatattc ttgaacccaa cggtagatcg ttgaatgatg aacgtttaca ccacgttctc
    20761 ttaatatttc agatatatca cgatagctca atgcatatct tagatagtag ccaacggcta
    20821 cagtgataac atccttgtta aattgtttat atctgaaata gttcatacag aagactcctt
    20881 tttgttaaaa ttatattata aattcaactt tgcaacagaa ccgtatttta tgagtacact
    20941 ctaaattaag gagatgtata atcaatctaa aattgtattt ttatactttt gttatataat
    21001 ctttctactt agagatatat tgtaaaaaaa ccaacaaaat gttatattaa cattactatt
    21061 ttatcgatga aggaggatta aaatgacagc ttctatgaga ctcaaataaa cctttttgaa
    21121 tacaaaacta aattaattca aaaaggcttg tccgcaatac acactcatag gatgacttat
    21181 gtcatttttt atccttcgat aggaataata aacgctttca aatactaaaa catcataata
    21241 aatttttaag tgtttgaaag tgtaatgtga atgagacggg agtagcctgt ctcatttttt
    21301 tgcgtacacg tcctttaaat atacaaggag tgtataaata tggaacaata tacaattaaa
    21361 tttaaccaaa tcaatcataa attgacagat ttacgatcac ttaacatcgg tcatctttac
    21421 gcttaccaat ttgaaaaaat agcacttatt gggggtaatg gtactggcaa aaccacatta
    21481 ctaaatatga ttgctcaaaa aacaaaacca gaatctggaa cagttgaaac ggttggcgaa
    21541 attcaatatt ttgaacagct taacatggat gtggaaaatg attttaacac gttagacggt
    21601 agtttaatga gtgaactcca tatacctatg catacaaccg acagtatgag tggtggtgaa
    21661 aaagcaaaat ataaattagc taatgtcata tcaaattata gtccgatatt acttttagat
    21721 gaacctacaa atcacttgga taaaattggt aaagattatc tgaaaaatat tttaaaatat
    21781 tactatggta ctttaattat agtaagtcat gatagagcac ttatagacca aattgctgac
    21841 acaatttggg atatacaaga agatggcaca ataagagtgt ttaaaggtaa ttacacacag
    21901 tatcaaaatc aatatgaaca agaacagtta gaacaacaac gtcaatatga acagtatata
    21961 agtgaaaaac aaagattgtc ccaagccagt aaagctaaac gaaatcaagc gcaacaaatg
    22021 gcacaagcat catcaaaaca aaaaaacaaa agtatagcac cagatcgttt aagtgcatca
    22081 aaacaaaaag gcacggttga gaaggctgct caaaaacaag ctaagcatat tgaaaaaaga
    22141 atggaacatt tggaagaagt tgaaaaacca caaagttatc atgaattcaa tttcccacaa
    22201 aataaaattt atgatatcca taataattat ccaatcattg cacaaaatct aacattggtt
    22261 aaaggaagtc aaaaactgct aacacaagta cgattccaaa taccatatgg caaaaatata
    22321 gcgctcgtag gtgcaaatgg tgtaggtaag acaactttac ttgaagctat ttaccaccaa
    22381 atagagggaa ttgattgttc tcctaaagtg caaatggcat actatcgtca acttgcttat
    22441 gaagacatgc gtgacgtttc attattgcaa tatttaatgg atgaaacgga ttcatcagaa
    22501 tcattcagta gagctatttt aaataacttg ggtttaaatg aagcacttga tcgttcttgt
    22561 aatgttttga gtggtgggga aagaacgaaa ttatcgttag cagtattatt ttcaacgaaa
    22621 gcgaatatgt taattttgga tgaaccaact aattttttag atattaaaac attagaagca
    22681 ttagaaatgt ttatgaataa atatcctgga atcattttgt ttacatcaca tgatacaagg
    22741 tttgttaaac atgtatcaga taaaaaatgg gaattaacag gacaatctct tcatgatata
    22801 acttaaaaac tatacactaa tttatattga atattaggtt catttatatc aatataaaaa
    22861 atacgttcac aagaaaaata taatagaaat aaggatccaa taaaatgact cgacataatg
    22921 aaattattaa atgtgcagaa aaatatcaat tacacatcca acctcaaaca atctcattga
    22981 atgaatcggg acttgatttt caagttgcat ttggaaaaga taaacatgga gtagaatggg
    23041 ttttgagact accaagaaga cctgacgttt ataaacgaac aaaacccgaa aaacaaacgg
    23101 tagacttctt acagaagaat gtttcatttg aaataccgaa gtggaaagta catgcaaaag
    23161 accttattgc ttacccaaaa cttacaggta aacccgcagc cacaatagat ccagaaatac
    23221 aaaattatgt atgggaaatt gaacacaaac cattaccaga aaactttatt aacacattag
    23281 ctgaaacact cgtagattta cacaacatac cagaagaaaa cattaacgtt cagcatataa
    23341 atatcaaaac catacaagaa ataaaaaatg actttcaaag aagaatgaat aaagttaaag
    23401 aaacttatgg cgtatcagat gaattatgga acagatggaa acaatggtta gaaaacgacg
    23461 aactatggcc tcgacatgcg accatgatac atggggactt acatccagga catataatgg
    23521 tagataacca agcaaacgtc acaggtctca tagactggac tgaagcaacc cactccgacc
    23581 catcaatgga ctttatagga caccatcgtg tattcgacga cgaaggatta gagcaactta
    23641 taacagcata cggtaaagct ggaggtgaaa tatggccacg aatgaaagag catataatag
    23701 aactcaatgc agtattccca atgtttatcg ctgagtttgc tatggaatca ggagaatcgg
    23761 cgtatgaaac gatggcattg aaagagttag gtatgaaaga gtagaactta tattaaaaga
    23821 ggcccatttt aaagacgaag gcaatcctga tgaaatttta aaactgcgtt taattagtga
    23881 tggtctttgg ttttctataa tgtattaaat atctggacat ggaacaaatg caacaaatgg
    23941 aaagaatcgt tttcgaaatt tctaactcct taaatcagga ggataaataa acggtcattt
    24001 tcattgaaag cacttatata aatttcatca attttaatac ctaccgtaaa tacatttcat
    24061 aagtattaaa cagatgatta aaatttttag ttaatttaaa tatttatgat agagatgacc
    24121 ttcaaatgaa cggttctgtt acaaagaaaa aatctatatt tatttttagt aagttttaat
    24181 tatagatatg tacactttga gtacacccta accatacaaa aagaattgtt gaaattataa
    24241 caattaaaac gtatgattag ggtgtatatt tattatggag tgaagatgaa tgattatagg
    24301 ttatgcgaga gtatcatcga tagatcaaaa tttagaaaga caattggata atttaaagac
    24361 gtttggtgtg gagaaaatct ttacagagaa acagtcggga aagtcagtgg aaaatagacc
    24421 tgtatttcaa gaagcactca attttgtcag aatgggagat cgattcgttg tggaatctat
    24481 tgatcgttta ggacgtaact atgatgaaat tattgaaact gtgaattatt taaaagaaaa
    24541 agacgttcag ttaatgatta ccagcttacc tatgatgaat gaagtaattg gcaatccatt
    24601 actggataag tttatgaaag atttaatcat tcaaatatta gcaatggttt cagaacaaga
    24661 gagaaatgaa agtaaacgtc gacaagcgca agggattcaa gttgcgaagg aaaaaggcgt
    24721 atataaaggg cgccctttac tttattcacc aaatgctaaa gacccacaga aacgtgttat
    24781 ttatcatcgc gtggtggaaa tgttagaaga aggcaaagcg attagtaaga ttgcgaaaga
    24841 agttaatatc acaagacaaa cagtttatag aattaaacat gataagggat tatcttgata
    24901 aattgattgt caatgcaaat gagcgtctct cacagtgtct caaattccat aacatattat
    24961 tgaattgaga ttttaataat tatacaagaa aaaagagtac gagttcgcag ctttctatat
    25021 agtaattgtt ttactaataa ggtgttttaa aatatattat aatgtaaaaa gtatttgaca
    25081 tttgtatcaa aaatatttac actcataaat gtcaaatact ttttacattt atgaggtgtt
    25141 ataatgaatt taattccttt tattattatt ttaatttttt cttgtttatg gacggctata
    25201 actaacaaat atttaccttc agaaacatta gataaaaaag gacaacaaga tcgatacgat
    25261 gaaagacaac gtaaaatgtt tattgaaata ctggctaaaa gttttatttg gattgtatat
    25321 tgtatgttat ttacactagt gcttaaattt acaggtttgt caccaagtat tgaaggatct
    25381 tggttttctc aatatccaga aattttcttt ataattgtag cactatttct tatgctgttt
    25441 aattactata ctacaaataa aaaatataca tctaaaggtt aaattaatga aaaatagaat
    25501 tagagaatat agaaaacaaa aaggaatttc tcaagaaact ttaagtaaag aattaaaagt
    25561 gtctaggcaa actattaatg caatagaaaa caataaatat gatcctacat tgacattagc
    25621 atttaagttg gcaagattgt ttgatacaac tgtggatgaa ttattttctt aaccattcat
    25681 ttatcacaaa aagagagtgc gaattcgcac tctctttttg tgtagtagta ctattaaatt
    25741 ttgtctcaat aacgaacgtt tataacgcaa tcatgatgag agtattaata cagttaatta
    25801 tttgaaatac tttagtttac ataatcgatg attaccagaa gttctcacta tataaaagac
    25861 actaaaattt tataactttt agtgcctaat caattatttt agctaccaaa caaacgactc
    25921 caaaacccct ttttaggttc cgtttcttca ctcttttctt ctatatcact atcattgtca
    25981 tttagattag ctggaacgtc ttcttttttt gcttcttcac cttgtgtact ttcgtcgctt
    26041 tgacttccag atatatcctt atattgaatc tctgtttctt tagtttcttc ctgatctctg
    26101 ttaatattta caggattagt agtatatgtt ttttcttgtg catcaacgtt ttgtctagtg
    26161 ttagtagatg tatcaaaggg ataattaagg tgtttttctt tttctaattg attttctaat
    26221 ttttgaatct ttttattact ctctaatgcc agaacttgct gattttcaag caattttgat
    26281 ctttcttgca actcttttct gtaaaattca attgttgttt catgacgact ttcttgtttt
    26341 tcaatttgat tatttaaagt atcaatctga tttttaagga tttctactat ttgagcatcg
    26401 cttttcgatt caaaattaat attatccgac cctttttttt gtttgtcttc agtagtactt
    26461 tcaaaaccat atttcttttt attttcattt actctttgaa tgattttttc tatatcggta
    26521 tcttctttaa taaacgaagt gttttcctgt tttattgtct ctatattcaa tcgcttaata
    26581 ttattaaaaa tcgtttgctt actaacccct aattcttcac tcaacttttt cacacttttc
    26641 atatcatcaa ccctttataa aatgtttata aacccttgat aaaatattat aagcttataa
    26701 tgcttaataa taaagtgatt aataaataaa aataaacatc catcaacctt tttatcaagg
    26761 gtttatgaaa ggtttatgat atttatcaag ggtttataaa cccttgataa agttatattt
    26821 tcccttttat aagtttattt aaagtgctat aataaactta atataacaaa aaccccaact
    26881 actggtaata gtcggggttt ggtaataaaa cgtttagaaa ctgtttattt atataatttt
    26941 cgatacttgt attatataat gaataatatc ttagtgcaag cacctaaatc attaaataaa
    27001 tgtaaagcta aataaaaacg ttttattacc tcttaccaaa ctaaaatatg gaaagaggtt
    27061 ttttgtc
//
