LOCUS       NC_018959              27059 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Staphylococcus aureus plasmid p18808-P03, complete sequence.
ACCESSION   NC_018959
VERSION     NC_018959.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224394
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27059)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Complete nucleotide sequence analysis of plasmids in strains of
            Staphylococcus aureus clone USA300 reveals a high level of identity
            among isolates with closely related core genome sequences
  JOURNAL   J Clin Microbiol 48 (12), 4504-4511 (2010)
   PUBMED   20943864
REFERENCE   2  (bases 1 to 27059)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2010) Laboratory of Human Bacterial Pathogenesis,
            Rocky Mountain Laboratories/NIAID/NIH, 903 S. 4th Street, Hamilton,
            MT 59480, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009948015.2-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:39:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 33
            CDSs (total)                      :: 33
            Genes (coding)                    :: 25
            CDSs (with protein)               :: 25
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 8
            CDSs (without protein)            :: 8
            Pseudo Genes (ambiguous residues) :: 0 of 8
            Pseudo Genes (frameshifted)       :: 4 of 8
            Pseudo Genes (incomplete)         :: 4 of 8
            Pseudo Genes (internal stop)      :: 2 of 8
            Pseudo Genes (multiple problems)  :: 2 of 8
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002137.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27059
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="18808"
                     /db_xref="taxon:1280"
                     /plasmid="p18808-P03"
     gene            1..978
                     /locus_tag="HS373_RS00005"
                     /old_locus_tag="SUH_0001p2"
     CDS             1..978
                     /locus_tag="HS373_RS00005"
                     /old_locus_tag="SUH_0001p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_015056160.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLKKKGLENDGLLIQKRRGLNKPN
                     ILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRKSN
                     TNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPEQL
                     TNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRG
                     VKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <998..1287
                     /locus_tag="HS373_RS00010"
                     /pseudo=""
     CDS             <998..1287
                     /locus_tag="HS373_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1486..1866)
                     /locus_tag="HS373_RS00015"
                     /old_locus_tag="SUH_0003p2"
     CDS             complement(1486..1866)
                     /locus_tag="HS373_RS00015"
                     /old_locus_tag="SUH_0003p2"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2151..2381)
                     /locus_tag="HS373_RS00165"
     CDS             complement(2151..2381)
                     /locus_tag="HS373_RS00165"
                     /inference="COORDINATES: protein motif:HMM:TIGR04450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_342749646.1"
                     /translation="MLINKNYVEYKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAH
                     YCGVWAIVNPIAGGVCEAVCGTAFAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(2318..2842)
                     /locus_tag="HS373_RS00020"
                     /old_locus_tag="SUH_0006p2"
     CDS             complement(2318..2842)
                     /locus_tag="HS373_RS00020"
                     /old_locus_tag="SUH_0006p2"
                     /inference="COORDINATES: protein motif:HMM:TIGR04450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_015056162.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKYLLTKITLN
                     IRLKKLIKTDR"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2952..3146
                     /locus_tag="HS373_RS00025"
                     /old_locus_tag="SUH_0007p2"
     CDS             2952..3146
                     /locus_tag="HS373_RS00025"
                     /old_locus_tag="SUH_0007p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4262..4879
                     /gene="cadD"
                     /locus_tag="HS373_RS00030"
                     /old_locus_tag="SUH_0009p2"
     ARG             4263..4876
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4898..5245
                     /locus_tag="HS373_RS00035"
                     /old_locus_tag="SUH_0010p2"
     CDS             4898..5245
                     /locus_tag="HS373_RS00035"
                     /old_locus_tag="SUH_0010p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5402..5494
                     /locus_tag="HS373_RS00040"
     CDS             5402..5494
                     /locus_tag="HS373_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5666..6637)
                     /locus_tag="HS373_RS00045"
                     /old_locus_tag="SUH_0011p2"
     CDS             complement(5666..6637)
                     /locus_tag="HS373_RS00045"
                     /old_locus_tag="SUH_0011p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6761..7180
                     /locus_tag="HS373_RS00050"
                     /old_locus_tag="SUH_0012p2"
     CDS             6761..7180
                     /locus_tag="HS373_RS00050"
                     /old_locus_tag="SUH_0012p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7706..8550)
                     /gene="blaZ"
                     /locus_tag="HS373_RS00055"
                     /old_locus_tag="SUH_0014p2"
                     /pseudo=""
     CDS             complement(7706..8550)
                     /gene="blaZ"
                     /locus_tag="HS373_RS00055"
                     /old_locus_tag="SUH_0014p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     gene            8657..10414
                     /gene="blaR1"
                     /locus_tag="HS373_RS00060"
                     /old_locus_tag="SUH_0015p2"
     ARG             8658..10411
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10404..10784
                     /gene="blaI"
                     /locus_tag="HS373_RS00065"
                     /old_locus_tag="SUH_0016p2"
     ARG             10405..10781
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11048..11626
                     /locus_tag="HS373_RS00070"
                     /old_locus_tag="SUH_0017p2"
     CDS             11048..11626
                     /locus_tag="HS373_RS00070"
                     /old_locus_tag="SUH_0017p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            12296..12970
                     /locus_tag="HS373_RS00075"
                     /old_locus_tag="SUH_0019p2"
     CDS             12296..12970
                     /locus_tag="HS373_RS00075"
                     /old_locus_tag="SUH_0019p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13139..13710)
                     /locus_tag="HS373_RS00080"
                     /pseudo=""
     CDS             complement(13139..13710)
                     /locus_tag="HS373_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(13986..14780)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HS373_RS00085"
                     /old_locus_tag="SUH_0022p2"
     ARG             complement(13990..14780)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14873..15403)
                     /gene="sat4"
                     /locus_tag="HS373_RS00090"
                     /old_locus_tag="SUH_0023p2"
     ARG             complement(14877..15403)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15400..>16035)
                     /locus_tag="HS373_RS00095"
                     /pseudo=""
     CDS             complement(15400..>16035)
                     /locus_tag="HS373_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16176..16850)
                     /locus_tag="HS373_RS00100"
                     /old_locus_tag="SUH_0026p2"
     CDS             complement(16176..16850)
                     /locus_tag="HS373_RS00100"
                     /old_locus_tag="SUH_0026p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16907..17083)
                     /locus_tag="HS373_RS00105"
                     /old_locus_tag="SUH_0027p2"
                     /pseudo=""
     CDS             complement(<16907..17083)
                     /locus_tag="HS373_RS00105"
                     /old_locus_tag="SUH_0027p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17097..17834)
                     /locus_tag="HS373_RS00110"
                     /old_locus_tag="SUH_0028p2"
     CDS             complement(17097..17834)
                     /locus_tag="HS373_RS00110"
                     /old_locus_tag="SUH_0028p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17827..18755)
                     /locus_tag="HS373_RS00115"
                     /old_locus_tag="SUH_0030p2"
                     /pseudo=""
     CDS             complement(17827..18755)
                     /locus_tag="HS373_RS00115"
                     /old_locus_tag="SUH_0030p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18871..19752)
                     /locus_tag="HS373_RS00120"
                     /old_locus_tag="SUH_0031p2"
                     /pseudo=""
     CDS             complement(18871..19752)
                     /locus_tag="HS373_RS00120"
                     /old_locus_tag="SUH_0031p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19749..>20126)
                     /locus_tag="HS373_RS00125"
                     /old_locus_tag="SUH_0032p2"
                     /pseudo=""
     CDS             complement(19749..>20126)
                     /locus_tag="HS373_RS00125"
                     /old_locus_tag="SUH_0032p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20184..20858)
                     /locus_tag="HS373_RS00130"
                     /old_locus_tag="SUH_0033p2"
     CDS             complement(20184..20858)
                     /locus_tag="HS373_RS00130"
                     /old_locus_tag="SUH_0033p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001106064.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYVLSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21332..22798
                     /gene="msr(A)"
                     /locus_tag="HS373_RS00135"
                     /old_locus_tag="SUH_0034p2"
     ARG             21333..22795
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22897..23796
                     /locus_tag="HS373_RS00140"
                     /old_locus_tag="SUH_0035p2"
     CDS             22897..23796
                     /locus_tag="HS373_RS00140"
                     /old_locus_tag="SUH_0035p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24282..24890
                     /locus_tag="HS373_RS00145"
                     /old_locus_tag="SUH_0036p2"
     CDS             24282..24890
                     /locus_tag="HS373_RS00145"
                     /old_locus_tag="SUH_0036p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25136..25474
                     /locus_tag="HS373_RS00150"
                     /old_locus_tag="SUH_0037p2"
     CDS             25136..25474
                     /locus_tag="HS373_RS00150"
                     /old_locus_tag="SUH_0037p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25479..25664
                     /locus_tag="HS373_RS00155"
                     /old_locus_tag="SUH_0038p2"
     CDS             25479..25664
                     /locus_tag="HS373_RS00155"
                     /old_locus_tag="SUH_0038p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25891..26634)
                     /locus_tag="HS373_RS00160"
                     /old_locus_tag="SUH_0039p2"
     CDS             complement(25891..26634)
                     /locus_tag="HS373_RS00160"
                     /old_locus_tag="SUH_0039p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22898..23793
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21333..22798
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22898..23796
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(14874..15391)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15698..15999)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7949..8550)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.37"
                     /coverage="71.17"
     ARG             complement(7707..7948)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.5"
                     /coverage="28.47"
     Typing          1344..1491
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..978
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.984"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1110..1279
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25892..26634)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaaaaa aaaaagggtt agaaaacgat ggtctactca ttcaaaaacg acgtggttta
      301 aataaaccaa atattctata tttaatgaaa cctattgtca cagaacgtga tatttacaaa
      361 atagaaaaag aagaaaacga tgttgaacct tacggcgaga aggaagttcg aaaatcgaac
      421 gtccagaagt tcgaaaatcg aacgtccaga agttcgaaaa tcgaacgtcc agaagttcga
      481 aaatcgaaca ctaatgatac tgactttaat gacattgact ttaatgatac tgagaataat
      541 gatatgaatg acttgaatga tataaagtac aaaaatgaaa ttagtaatca ttcaaatcat
      601 tcaaatcaat ttacacataa ttttgatgat aaagaaatgc tattgcaaga attcccagaa
      661 caactaacta attatttatt aaaatatgat tatagagatt tagaaatcat aaaggctgtt
      721 attcttaaag caaaaaaatc atttaattca aggcatgaag atatgcatta catgttagag
      781 gacattgagg atgaaatatt aacttcttta aaaagactta aaaaagctat acatgatagg
      841 ggagttaaag gccaaaagga aacaatcaag tcaatgcaag cttatttaat gcaaacaatt
      901 ctaactgaac ttgaagaaac acatgccctt tatatgcgcc gtaaaaacat gaaacaatat
      961 aatatcttta atcaataatt caaatgattt tataacactc gaagagacat caaaatattc
     1021 cgttaaatca tctgactttt taactgatga cgacgaaaaa aatcaagaaa ttgtaagtga
     1081 tttagaaaaa ggtttgtatc gaaaacgtat gttaagttat ggtggattgc ttaaacaaaa
     1141 gcataaaatt ttaaacttag acgatgccga agatggtaat ttgattaata caagtgatga
     1201 agataaaacg acagacgaag aaaaaaagca cattcaatta ccgcaatttg gaatttcgaa
     1261 aagcaaaatt attatttaag acattagtga taactgatgt ctttttttat tgtttttctg
     1321 taaaaaagtg ctgtcttatt tttgtgacaa atgctgtatg tagtgtcaca aaagtgtgac
     1381 actacagctt tgtatgatat cactttaaaa taacttaaaa cccttggaat gtctggcctt
     1441 gccagatcta tcatttttga atgatagcaa atttccctta tgctcttacg gagattttag
     1501 agttaaatta aaatttctaa gtttttgata agaaaagccc tgcaggaatt tagaaaaaca
     1561 tggggaagtt ttaaagtatt ttatgctaat ttttaaattt gcatgtaaat gggcagtatc
     1621 taaaaaatta gtcactgatt ttgctgaaat ttttgtttgt gaaattagca tatatttatt
     1681 tggctcatat ttgcgtttta agagactgta tagattttta agtacaaaac ctatatgatt
     1741 tgcctctaag tcttcaaaat gcctcttaaa atccaaaata aaagtgttta atattgtaat
     1801 aaggattgct atttttataa aaggagagat atcatgaaga ttaaaacttt cgctactttt
     1861 actcatcgtc aattagataa acaagttaat aggtttttaa agaatgatat tcatgtatta
     1921 gaaattcaaa cacacagtaa ttggttatat atttcagcta ttgtttttta tgaggataaa
     1981 taaggaacat cgtatttatg ccgaaaaaat ttattgatgt tgagaagaac ccttaactaa
     2041 acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg
     2101 gattgttaag ggttccgagg ctcaacgtca ataaaacaat tggaataaaa tcaacctaca
     2161 gagcatccag ctgcaaatgc agttccgcaa actgcttcac atacaccgcc ggctattgga
     2221 tttacgattg cccatactcc acagtagtga gcacatgcat aaagtccagc catactacaa
     2281 gcgaatgctt tgccgttcca tttgaatcct gcatatgtta ccggtctgtt tttatcaact
     2341 ttttcagcct tatattcaac gtaatttttg ttaataagta ttttccctct ttgttttcag
     2401 tcatacttct tttttcggca atgaattttg tgattttttt gttgtagtta tcatatattg
     2461 tttcagaaac tacaatttct tttgtttttt catttttata agcgttatta gctatgtagc
     2521 catatgcatt tttatcattt gcttctgtag ctagatattt taatttagaa tttttgtctt
     2581 ctagctttat ttttttaaat ccttcttttt tcatttgctt ttcgaatttt tgcatatctt
     2641 catttttatt ttgcaattgt tctagaaaac ttatttcttt cttggtcatt tgtgatactt
     2701 cgatgttttt gcttttcaat ttttcttttt gattttctag taaagaactt ttttgttctt
     2761 catttgcgta agcattagaa aaattcgcgc taaataccag taggaacaag gaaattattg
     2821 aaaataattt tataattttc atttgatacc tccaagataa taagatattt taattgtata
     2881 agtaagcgct ttataaaatc aatatttatt ttaatatatt tataaacata tttttgaaag
     2941 gagtctattt tatgaatgaa aatttagaaa aatatataaa aagtttgcca cttttaggtt
     3001 tgttaattag tattttgtta attgttttat tcttttttat tttagatgtt gatgaagatt
     3061 tattcgtggt ttttttatac tgtttattgc ctttgatagt taatttgtct atttatggtt
     3121 tttatgtttt tgttaaaaga aagtaagatt atgaataatt ttgtttttaa tttgtatgct
     3181 ttgagggggt tggaaaacgg taggtgtata gattagattt cttgtttttt tgaaacgagt
     3241 gtgaacgagt ttcttcttgt cttgattttt gataaaaacg ccctacagga atttagaaaa
     3301 acgtggggaa gttttaaaga attttatgct aatttttaat ttgcatgtaa atgggcagtg
     3361 tctaaaaata gttattgttt ttgctcaaat ttttgttttt gaaaatagca tatatttatt
     3421 tggctcatat ttgcgtttta aaagcatata taagttttag atataaaact atatgaatca
     3481 cccctaaatc tttaaaatgc cctcttaaaa ttcaaaataa gggcataaaa aataaaagct
     3541 accccagata aagtgaggta gctttttctt tcatacggtc tatttatttt tctttcgacg
     3601 ccgtatcgtc gatgtaattc aaaaaagtta tgggctataa atctacatca ctttttcaag
     3661 aatgtagtag caatattcaa cgcaaattaa tttttataac tgctcggaat atctcaagcc
     3721 gtttctttaa ttttgaaata aaaaaatcga cgaaggtcga ttacgttttt gcacatgtcg
     3781 atttatccga cgtataagtg cgcccttacg ggatttaact agattataac gacgaatttt
     3841 agacctgtaa agcaataaca attaggtcta ccaggtagat aaagtgtaca aagtagaacc
     3901 gaaaaagtta tttattttga agatttttcg tagatataat ttgctaataa acttcctaaa
     3961 actgaataaa gaaaaatagt taaactcatg taatcactcc ataattctga agtgtctcca
     4021 tgtctacgca tagacacgca tttatgccga aaaaatttat tgatgttgag aagaaccctt
     4081 aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag
     4141 ttttgggatt gttaagggtt ccgaggctca acgtcaataa agcaattgga ataaagcacc
     4201 tatgattatt taaaaatata agttataata cattcaaaaa tatttttgaa tgaggtgtat
     4261 tatgattcaa acggttgttg ctgctgctgt tctttatatt gctacagcag ttgatttatt
     4321 agtaatttta ttaatatttt ttgctagagc aaagactaga aaagaatata gagatattta
     4381 tgttggtcaa tatttagggt ctattatttt aatattagtt agtttgtttt tagcttttgt
     4441 attaaattat gttccagaaa agtggatatt aggtttattg ggtttaatac caatttatct
     4501 tggaattaaa gtggctattt atgatgattg tgaaggagaa aagagagcta aaaaagaatt
     4561 gaatgaaaaa ggattgtcta aattagttgg tacggttgca attgttacga tagcaagttg
     4621 tggcgccgat aatattggtt tatttgttcc gtattttgtg acattaagtg ttactaattt
     4681 attacttact ctgtttgtct ttttaatttt aattttcttc ttggtgttta ctgcacaaaa
     4741 attagctaat attccaggaa ttggagaaat tgttgagaaa tttagtcgtt ggattatggc
     4801 tattatttat atagctttag gtttatttat tattattgaa aatgacacta ttcaaacaat
     4861 tttaggattt atattttaat ttagggtgtg attttatatg agttatgaaa atacttgtga
     4921 tgtgatctgt gtacatgagg ataaagttaa caatgcttta agttttttag aagatgataa
     4981 atctaagaaa ttacttaaca ttttagaaaa aatttgtgat gagaagaaat tgaaaatcat
     5041 attatctttg attaaagaag atgagttgtg tgtttgtgat atttctttga tattgaaaat
     5101 gagtgttgct tcaacttcac atcatttaag gcttttatat aaaaatgagg tacttgattt
     5161 ttataaagat ggaaagatgg catattattt tattaaagac gatgaaataa gagagttttt
     5221 ctctaaaaat catgagggtt tttgaaacga gtttcttctt gtcttgatac tataaaaaac
     5281 aaagttatat aacataagac gacttatcgg aagtagatat gcttgtatat tcacagatgg
     5341 tataataata gagtcgccta tctctcaggc gtcaattgac gaagagagga ggtgcattac
     5401 tttgctaatc attttcgttc acatcatagc accagtcatc agtggctgtg ctgttgcgta
     5461 ttatacttat tggcttagta aacgcaacaa ataattaata ggcgacttta taagccagca
     5521 tcgaaaaaat ccccacacta ctgcaatagt gtggggattg gtgcattaat tgttaatcat
     5581 tttcgttata taaattataa cactggttag tagagaaatg caaaatgatt gaattaatag
     5641 taaatgtatt aatgaatact cacacttata cttttaaaat agttcttcct aaatgttgtc
     5701 cttttaaaag ctgatctatc gttttataga attcttcaaa tccaatttca ttgtatagaa
     5761 gtgaatttcc tatattccat tcatttgcta acttactcca tatatcttca cggatattat
     5821 gatcaacata tacagaatca atgccaatta atttaatacc tctaagaata aacggtaata
     5881 tattagcgtt aagtgaattt cctgctacat ttccacatac agtagcaaca ccttgataat
     5941 ttagacgttt taaaccgtat aatgttacat tactccccac tgtatctaag aaataatcaa
     6001 aaataccttt tttaagcggt ttattatcat cttcaattat tattacttgt tttgcaccta
     6061 atttttttgc gatttctatt tgcttttctt ttcttacgat agcagtgata ttttcatatc
     6121 caattttatg taaaatttgt atagcaacac tgcccacacc acctgtagcc ccagacacta
     6181 aaatttcagg ttgtgatttg atattcattc catatttttc tagttcaaaa attgataatg
     6241 ctgccgtaaa accggctgtg ccatatacca tagactcttt aatagacatt tcttggggaa
     6301 taggaacaat ccactctcca ggcacttgtg catattctga aaatccacct gtatgtgtca
     6361 cgccaacatc ataaccagta actaatacat tatcgccttc tttaaactta tcattcgaac
     6421 ttgattcaac aatacctgca aaatctatac caggaatcat aggataatct ctaattacac
     6481 cgcctttata ttgtaaagct agcatatcct tataatttat tgaagagtat accactttta
     6541 ctaatacatc acccttcgat aaatgagatt catcaacttt ttctacttta taactaacat
     6601 ttgatgcact ttttctcact actaccgcat tgaacattta ttagccttct ttcacaattg
     6661 ttttgtagaa gtatgttttt gttgcaaaac tattttccta caaaacttat catgatatga
     6721 taagcgagtc aatactaatg atttaagaga ggttttagtt gtggaattag ataattgtat
     6781 aaattatttg ttgagtactt ctcagaatag agtttttaaa cattttaaaa gtttattaag
     6841 tccctataat attactccag cagaatatgg tgttttgaat tgcttgatta atagtaattt
     6901 gaatacacct aaagcgattg gtaatacttt aaatttagaa ccttcaacaa tatctggaat
     6961 attagataag atgtccaaaa aggatctaat aacacgtcaa actgataatg aaaatagaag
     7021 aactgtgcta ataaacagta caaataaagc aaaagactta tggccaacat tagaaaagaa
     7081 agcctatcaa cttaataatc attacttcgc taatttaact aatgaagaaa ctgtagtgtt
     7141 taaaaagata ttactaaaga taaataaaac tacgttttaa tttttacgtt ataaaaaagt
     7201 tgaagtgcga attataatcg agtaaatata aatgatagct tagcttaatt atatattaaa
     7261 gccaactata cttttattcc cgaaaaacct actatccaaa tttctaagat actttagcct
     7321 ctataataaa catattgtaa tataatttat gtattattta ggtttaccct aatcgaacaa
     7381 taaaaaatac ttgtaaaatg ctattgtcac tttgcttgat atatgagaat tatttaacct
     7441 tataaatgag aaaaaagcaa cgcactttaa ataagatacg ttgctttttc gattgatgaa
     7501 cacctataat taaactattc atctattatt tatgattttt tgtatataca atatttctag
     7561 tttgttaaag agaattaaga aaataaatct cgaaaataat aaagggaaaa tcagtttttg
     7621 atatcaaaat tatacatgtc aacgataata caaaatataa tacaaactat aagatgttat
     7681 cagtatttat tatgcattta gaatattaaa attccttcat tacactcttg gcggtttcac
     7741 ttatcaactt atcatttggc ttatcacttt tattgtcttt attcgtaaaa atgactaaaa
     7801 caataggttc agattggccc ttaggataaa caaaagcaac atcatttcta gaagcatatg
     7861 ttattgcttg accactttta tcagcaacct tatagtcttt tggaacacca tctttaatta
     7921 aagtgtctcc gtttttatta ttaaacatta aatcaagtaa gaaattttta tttttttgct
     7981 taattttcca tttgcgataa gtttatttaa agtcttgccg aaagcagcag gcgttgaagt
     8041 atcttttttg ctctttggtg aatagtaatt taattctatc tcatatctaa ctggatttgt
     8101 tactttatct cctagttctt ttagacgttg tttaactttt ttgattccac cgatttcttt
     8161 tataatttta ttgtttgctg tattatcact atatgtcatt gaagcctcaa taagttcttt
     8221 taaagtgata tcttttccta catatttttc taaaatagga gaataagcaa ctatatcatc
     8281 tttgttaata tgtacttttt tatttaactt attataaggt acttgttcta acaaaatagc
     8341 actatttatc gcttttgaag tcgaagcata ggcaaatctc ttatctgaat taaattttac
     8401 ttccttacca cttttagtat ttaaagcata aacaccaata tgagcattat attttttttc
     8461 taaatcattt aactctttgg catgtgaact gtttgaatta catgcactta aaactaaagc
     8521 aattacaatt aaaaatatta actttttcaa aataaaccct ccgatattac agttgtaatt
     8581 tttataaatc aataatatta caattgtaat attgatgtca attgtttatt ataaatattt
     8641 gaaagaaggt gtcaaaatgg ctaaattact aataatgagc gtagtaagct tttgttttat
     8701 atttctattg ttagtatttt ttaggtacat attaaaacgc tattttaatt atagtttaaa
     8761 ttataaagtt tggtatctaa ctatgcttgc tggattaatt ccttttatcc caattaaatt
     8821 ctcttttata aaatttaata atgtgaataa tcaagcgccc acagttgaaa gtaagtcaca
     8881 cgatttgaac cataacataa ataccaccaa acctattcaa gagttcacaa cagatatcca
     8941 taagtttaat tgggattcaa ttgataatat ctgcacagtt atttggatag ttttagttat
     9001 tattttaagt tttaaatttt tgaaagcctt attatatctt aaatatttaa agaaacagtc
     9061 actttatcta aacgaaaatg aaaaaaataa aatagatacg atacttttca accatcaata
     9121 taaaaaaaat attgtgattc gaaaagcaga ggctattcaa tctccaataa ctttttggta
     9181 tgggaaatat attattttga ttcctagttc atattttaaa agtgtaattg ataaaagact
     9241 aaaatatata atactgcatg aatatgctca tgctaaaaat agagatactt tacatttaat
     9301 tatctttaat atcttctcta ttattatgag ttacaatcca ttagtacata ttgtaaaaag
     9361 aaagataatt catgacaatg aagtagaagc cgatagattt gtccttaata atattaacaa
     9421 aaatgaattt aaaacttatg cggaatctat tatggactcc gtattaaaaa ccccattttc
     9481 caacaaaaat atattaagcc attcatttaa tggtaaaaaa tcattactca aaagtagatt
     9541 aattaatata aaagaagccg atctgaaaaa gcagtcaaaa ttaattctaa tttttatttg
     9601 tatttttact ttttttatca tgataattca aagccagttt ttaatggggc aatccttaac
     9661 tgattataat tataaaaagc ccttacaaag cgattaccaa attttagatg aaagtaaaaa
     9721 ttttggttca aatagtggat ctttcgttat gtacagcatg aagaaagaca aatactatat
     9781 ttataatgaa aaagaaagta gaaaaagata ttctcctgat tcaacttaca aaatttattt
     9841 agcactgttt ggacttgacc gtcatattat aagtgataaa aattcacgta tgtcatggaa
     9901 tcataaacat tatcttttcg agtcttggaa taaggaacaa gatttaaata cagcaatgca
     9961 aaattcagtt aattggtact tcgaacgtat tagtaatcaa ataccaaaga actatactgc
    10021 ggctcaactc aagcaattaa attatggtaa tgaaaatttg ggaagttata aaagctattg
    10081 gatggaagat agtttgaaaa tatctaatct tgaacaagta atagttttta aaaatatgat
    10141 ggaacaaaat aaccatttta gtaaaaaagc aaagaatcaa ttatcttctt cattattgat
    10201 taagaaaaat gaaaagtatg aactgtatgg gaaaacaggt acaggtatag taaacgggaa
    10261 gtataataat gggtggtttg taggttacgt aattacaaat catgataagt attattttgc
    10321 tacacattta tcagatggaa acccgtctgg gaaaaatgct gaattaataa gtgaaaaaat
    10381 attaaaagga atgggtgttt taaatgacca ataagcaagt tgaaatatct atggctgaat
    10441 gggatgttat gaatataata tgggataaaa aatcagtatc agctaatgaa attgtagttg
    10501 aaattcaaaa atataaagaa gttagtgata aaacgattag aacattaatc acaagactat
    10561 ataaaaaaga gattataaaa cgatacaaat cagaaaatat ttatttttac tcatcaaata
    10621 ttaaagaaga cgatattaaa atgaaaactg ctaaaacctt tcttaataaa ctgtatggag
    10681 gggatatgaa aagtttagtg ctgaattttg cgaaaaatga agaattaaat aacaaagaaa
    10741 ttgaagaatt gcgagacatt ttaaatgata ttagtaaaaa gtaattagag gtatgtttca
    10801 aacataatac atatgtaaac catacttgac tcttattaaa ttagttttgt taatgacatt
    10861 taaaatatat tattaaagat gagagtgtcc agaaaataac cattttctgt acactcttgt
    10921 tttttgtcta aataagtaag tattacatag aattatgtgt tcaaaaaccc aacaaaaaat
    10981 ctatgttcac aaaagacctc gtaatcaagt tatggtacac taaaggtgta tataggaggt
    11041 ctgtattttg aaaataggtt atgcaagagt ttcaactgga ttacaaaatt tgaatttaca
    11101 ggaggatcga ttaaatacat atggttgtga aaagatattt aatgaccata tgagtggttc
    11161 aaaaagtaag cgacctggtt tagataaagc aattgaattt gcgaggtcag gagatacgat
    11221 tgttgtttgg agattagata gactaggacg gaacatggag gatttaatca cgttagttaa
    11281 tgaacttaac gaacgaggtg tgagttttca tagtttagaa gaaaatataa cgatggataa
    11341 atcaagttct acaggacaat tattatttca tttattcgca gcatttgcag agtttgaacg
    11401 taatttaatt ttagagcgat catcagccgg tcgaattgca gcacgtgcta gaggccgata
    11461 tggaggtaga cctgaaaaat taaataaaca agatttaaac ttacttaaga cactttatga
    11521 taatggtacg ccaattaaaa caattgcaga gcagtggcaa gtttcacgta caactattta
    11581 tcgttatctc aataaattag aggcaaaaga gaataaaaac aagtagagca actaatctag
    11641 cttactataa tgaatctact aaataatttt atatatcatt aacatacaaa gactttgatt
    11701 caatgtcact cgatgtaaaa gagacgttct gacagcgtct aaaatctcat aatattttcc
    11761 tgttatgaga ttttaataat aacacaagaa aaaagcgtac aaattcgtac gcttttttaa
    11821 tataatacct gtttcactaa tgaacgtttt aagtatcttc atcattaact gaaactacag
    11881 taataatact cgtcaacaat attagtatag ttaaaataga aagacttagg actggcataa
    11941 ccgaactaaa attatatttg aaatataaaa gtgctaatga agagagaaat gtaaaaataa
    12001 taaataccaa agaccatttt tctaatttat tcattggctt cacctctttg aacttttata
    12061 taatcatagg agatattttt actacgattt ataaaaaata agaagataat cattattaaa
    12121 gaaacgatta atataatgtt gaatcctata gtatcaccta attcgtttac acctttgcct
    12181 aatatcggag atacaaagct ttgtattaat aatgaaagag atgcccatat agtaaatgag
    12241 gttctgttgc aaagttgaat ttatagtata attttaacaa aaaggagtct tctgtatgaa
    12301 ctatttcaga tataaacaat ttaacaagga tgttatcact gtagctgttg gctactatct
    12361 aagatatgca ttgagttatc gtgatatatc tgaaatatta agggaacgtg gtgtaaacgt
    12421 tcatcattca acggtctacc gttgggttca agaatatgcc ccaattttat atcaaatttg
    12481 gaagaaaaag cataaaaaag cttattacaa atggcgtatt gatgagacgt acatcaaaat
    12541 aaaaggaaaa tggagctatt tatatcgtgc cattgatgca gagggacata cattagatat
    12601 ttggttgcgt aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa
    12661 acaatttggt aaacctcaaa aggtaattac agatcaggca ccttcaacga aggtagcaat
    12721 ggttaaagta attaaagctt ttaaacttaa acctgactgc cattgtacat cgaaatatct
    12781 gaataacctc attgagcaag atcaccgtca tattaaagta agaaagacaa ggtatcaaag
    12841 tatcaataca gcaaagaata ctttaaaagg tattgagtgt atttacgctc tatataaaaa
    12901 gaaccgcagg tctcttcaga tctacggatt ttcgccatgc cacgaaatta gcatcatgct
    12961 agcaagttaa gcgaacactg acatgataaa ttagtggtta gctatatttt tttactttgc
    13021 aacagaacca gcatttgttt taatatttgt tccaaagagc catcatggct ttgacagagc
    13081 tcttcttcta tgcaaatgct tttaatccga tccacacgaa aattcctata ttcatttctt
    13141 agcctgcaaa accgattaag taccagttct gttcataaaa ccccagtgat ataggctcta
    13201 tcattctgct ttccggttct tgccctcctg atgcaggata ttgaattgat attacccttt
    13261 tattgcagat tgcagtctga attgctgcaa taacgttatc cgccaatgta tttttctgtc
    13321 cagatgtgct gtacacgtta atactgttct ccaactcctg tgcatagttt ttttcaccat
    13381 gcttcaaaat agatttgatt ttatacatag ctgaatcaaa atcctttata aatgattcat
    13441 ctccatggca atttaaaaat ttccctgctg taatcaatgc acccacttcc gccgctgtaa
    13501 acattaccgg cagaagtagg aagccctcta caagaaaata tccttttccg gcctcagatc
    13561 caattggtat tccggcttct tcaagtgtcc ggatatctct gtaaactgtc cttaagctta
    13621 tattaaatcg ctgtgcaatt tctttggcag gaattatttt tttgattgca gctgaataag
    13681 aatagaggtt actctgttaa tcctgttcaa attttattcc tcctctgtga cttccataaa
    13741 aagtatatcc tatgcgttct taagctagct gctgttagtg cttctcattg caccctggtt
    13801 ataaaagcca tactcacaaa cctcttcacc aaaactcttt acatctctaa tatagaactc
    13861 tatctagcga acttttagaa aagatataaa acatcagagt atggacagtt gcggatgtac
    13921 ttcagaaaag attagatgtc taaaaagctt gtagttaaag ctttttagac atctaaatct
    13981 aggtactaaa acaattcatc cagtaaaata taatatttta ttttctccca atcaggcttg
    14041 atccccagta agtcaaaaaa tagctcgaca tactgttctt ccccgatatc ctccctgatc
    14101 gaccggacgc agaaggcaat gtcataccac ttgtccgccc tgccgcttct cccaagatca
    14161 ataaagccac ttactttgcc atctttcaca aagatgttgc tgtctcccag gtcgccgtgg
    14221 gaaaagacaa gttcctcttc gggcttttcc gtctttaaaa aatcatacag ctcgcgcgga
    14281 tctttaaatg gagtgtcttc ttcccagttt tcgcaatcca catcggccag atcgttattc
    14341 agtaagtaat ccaattcggc taagcggctg tctaagctat tcgtataggg acaatccgat
    14401 atgtcgatgg agtgaaagag cctgatgcac tccgcataca gctcgataat cttttcaggg
    14461 ctttgttcat cttcatactc ttccgagcaa aggacgccat cggcctcact catgagcaga
    14521 ttgctccagc catcatgccg ttcaaagtgc aggacctttg gaacaggcag ctttccttcc
    14581 agccatagca tcatgtcctt ttcccgttcc acatcatagg tggtcccttt ataccggctg
    14641 tccgtcattt ttaaatatag gttttcattt tctcccacca gcttatatac cttagcagga
    14701 gacattcctt ccgtatcttt tacgcagcgg tatttttcga tcagtttttt caattccggt
    14761 gatattctca ttttagccat ttattatttc cttcctcttt tctacagtat ttaaagatac
    14821 cccaagaagc taattataac aagacgaact ccaattcact gttccttgca ttctaaaacc
    14881 ttaaatacca gaaaacagct ttttcaaagt tggcgtataa catagtatcg acggagccga
    14941 ttttgaaacc acaattatga tagaatttac aagctataag gttattgtcc tgggtttcaa
    15001 gcattagtcc atgcaagttt ttatgctttg cccattctat agatatattg ataagcgcgc
    15061 tgcctatgcc ttgccccctg aaatccttac atacggcgat atcttctata taagcgtacc
    15121 ggttccaatt ttttcgcagt ttaacttttc cgacgcattt atcgtcttgg tagtaaagat
    15181 atattatctt atcagtattg tcaatatatt caaggcaatc tgcctcctca tcctcttcat
    15241 cctcttcgtc ttggtagctt tttaaatatg gcgcttcata gagtaattct gtaaaggtcc
    15301 aattctcgtt ttcatacctc ggtataatct tacctatcac ctcaaatggt tcgctgggtt
    15361 tatcgatatc tttcaggtgc cctgctttca tttctgtaat cactgttccc gcctctcttc
    15421 tatatcagcg gcatatgtgc tatccaggca gccggtttta ccagtgtatt ttttatacat
    15481 gtccctggta tattttgtta tattcctatc atactccgga taggcataat gaagcctttc
    15541 cgccacctca ccggataccg ccctgaacaa ttgatggcat agaaataatg cttcccatat
    15601 gttttcatag gaatccatcc ggtaggtgga caaaagtttc tcccacaaat cctcggatat
    15661 atacctttca ataaacttat agttcttgcc tacacttcat ttaaagcctg tttcgatgcc
    15721 gaccttccat gatatcattc tcagcagctc atggcgaaca atctgattaa aatgatcaat
    15781 agcaaataaa atttccttac ggcacaatcc tttaataaca taaggtgtta cattccaaaa
    15841 ttcattgcag caatcatcat actcccttgc gcttggcttt cttacatgat aatctatatc
    15901 agtcggaact atgtcccttt taattctaca atctttatca attagaacct ttattaattt
    15961 atcgcccttt aggtaattat ctaactcttc caagggcaat aaggtaagat caattttatt
    16021 gtaatcatca aatagctata atagatttag aggtaaagaa attaaataca ttgaagagca
    16081 gaaagatttt acaaaagagt attttaataa aaatgatggt tctgttgcaa agtaaaaaat
    16141 atagctaatc actaatatat catgtcagtg ttcgtttaac ttgctagcat gatgctaatt
    16201 tcgtggcatg gcgaaaatcc gtagatctga agagacctgc ggttcttttt atatagagcg
    16261 taaatacact caataccttt taaagtattc tttgctgtat tgatactttg ataccttgtc
    16321 tttcttactt taatatgacg gtgatcttgc tcaatgaggt tattcagata tttcgatgta
    16381 caatggcagt caggtttaag tttaaaagct ttaattactt taaccattgc taccttcgtt
    16441 gaaggtgcct gatctgtaat taccttttga ggtttaccaa attgtttaat gagacgtttg
    16501 ataaacgcat atgctgaatg attatctcgt tgcttacgca accaaatatc taatgtatgt
    16561 ccctctgtat caatggcacg atataaatag ctccattttc cttttatttt gatatacgtc
    16621 tcatcaatac gccatttgta ataagctttt ttatgctttt tcttccaaat ttgatataaa
    16681 attggggcat attcttgaac ccaacggtag atcgttgaat gatgaacgtt tacaccacgt
    16741 tctcttaata tttcagatat atcacgatag ctcaatgcat atcttagata gtagccaacg
    16801 gctacagtga taacatcctt gttaaattgt ttatatctga aatagttcat acagaagact
    16861 cctttttgtt aaaattatat tataaattca actttgcaac agaacctcct aactgtatta
    16921 ccaccttaaa agtagttgca gacgcacttc ctaaatcgtc agcagtgttt aaccacatat
    16981 catcaacaat aatcatatga cctgttgatg atactggagc aaattctgtc aacccttcaa
    17041 ctacacctaa aataaatgct ttaatctgct ctataaaacc catttttctc ctccttttaa
    17101 cttatatcag tttttttaaa gtatgagaat aatataatta cactgaatat agatgtaaca
    17161 attatgataa ttaaagataa tagaaatgga taagtattag gtaatgttcc tctagatatg
    17221 tctccaactg cagcccaagg aaataatcct ctatgttcag aattagcagt cattaaattt
    17281 atcaaagtaa ttattatggt taaaacaatt gtgggaacat aatttttaaa atatatcgac
    17341 aaaataatta ttggtggaga taatatccat aataacactc cgccaataac aaatgtaaag
    17401 aatgaatcaa ttattaaact ctggcttaac ccttgaaaat gcaatagcat acctagcatt
    17461 aaagttagca accatgcaat aacagatagt gtttgaatcc acaagaataa taatattatt
    17521 ttacttacta aaaaactttc tctagatata ggtataatta ataagttttt taaagtatct
    17581 tctatatatt ctcttccaaa caaataggct attataaccc catatagagg aggtccaata
    17641 attagcatat gatataaact gacttcttca aataactgtt taaatacaat attaggagtc
    17701 ggtactttcg tccgcatact aataaaagaa gctacaacca ccataaaagg tgctacgcat
    17761 gtacctaaaa tacttattag aaacatatat gatcttttta acttaataaa ttctgtacgg
    17821 agtagattat ccaattgtgc cacctcctac taagtcttcg aaataagttt ctagattatc
    17881 ttctatcact ctcatctgga aaacatcaat attgtttaat actaataatc tattaatttc
    17941 ttgttgtcta tcaatatgtg aataaatttt aaattcgcca ttttctttaa ttttatagtc
    18001 ataaattccg aagttagttt ccaacaaaca tgcaactttt tcttcatctg atactgatat
    18061 acttataaat tgtctgttct tttttttaaa tcttcataca taatttcttc taacaaaact
    18121 ccgttatgaa taatacccac cttgtctact aactgctcta tttctgacaa tatatgactt
    18181 gaaattaaaa tggttatatt tctagattga gccagatcct taatcaactt tctaatttct
    18241 tttatgccaa taggatctaa tccattcgtc ggctcatcaa gtatcaataa ttcgggattg
    18301 tgcaataaag ctctcgcaat ccctaaacgt tgcttcatac ctaaagaata atttttaaac
    18361 aattttactt tttcagaagc tagtcctact atttctaaca cttcttcaat tgcattttct
    18421 ttttgtatac ctaatatttt agcatttata gttaagttct ctttagctgt caaattacta
    18481 taaaaacctg gcgtttcaac catagcacca atatttttta aaatttcagt tttattactt
    18541 tcgaactctt tttcaaatat tttaatatta cctttcgtag gtttaattaa gcctaaaagc
    18601 attcttatag tagttgtttt gcctgcacca tttcttccta aaaaaccata aatttgtcca
    18661 ctttcaacag ttatactcaa attattaact gctatctgac ttccatattg ctttgttaag
    18721 ttatttattt caattatatt attcaaattt ttcacctctg gcacctttct tagtttgttg
    18781 ttacctttat cttacgcgcg attagaaaag gctgccttta tctattctta caaaaacagc
    18841 cgctaatctt acaaaaatga aagattggag ttatttaaat tgaatggtga atattgaacc
    18901 atcgtttaat gtagatgtag cacttacttt atggcctaag cgctttgaga ttgtgctgac
    18961 aatatataaa ccaataccgc ttgatttctc acttattcta ccgttatagc ccgagaaacc
    19021 tttatcaaag attttcggta aatcactcgc attaatgccg ataccgttat ctcggattga
    19081 taatttcttt gtattttcgt caaacgtaat ccacacatct ttgccacgtg catattttaa
    19141 tgcattgttt aatatttgct caatcataat tgatgcccat ttggcatctg ttaatataac
    19201 cgcttcactt ttctcataat gcaactttgt ttgatgatga ataaactgta tcgcataacg
    19261 tttaatcagt ggtcgaatta attcatctac actcacttcc ataaagacca tgtatgtctt
    19321 ttggttcatg agtttcaaat agttcagtgc aagattcgtg taattatcaa tttgtaagac
    19381 ttcattacgc acgttagaaa tcacgtgttc atcaggatct tcaagcagta actttgatgc
    19441 tgtaatcggt gtcttgattt gatgcaccca cattaaaaaa tatgactcta actcactttg
    19501 gtagttaata aagtcattac gaagtttatg gttttcgatt cttaaatctt cgttctgttc
    19561 ctgtagtgtt tattcttttt taaagttcat gtaatggata ccccagtaaa tcattgaaac
    19621 aaacaataca atacctagac caatcatata tgcttgcatc ggcacattat acatgaataa
    19681 tataaagtag aataaagcac aagtaaggat gacaatataa atttcacgtt ggattgattt
    19741 caagaaattc atacgtcacc tacacgatat ccgacatttt tcttcgtttc gataaaatct
    19801 gtaagtccta gtttttgtag ctttttgcgt aaacgtgtaa tgttgacagc aagcgtattg
    19861 tcatcaatga agtgttctga ttcccagcat ttttcgatta acgcattacg actgacgaat
    19921 ttgcccttgt tctggaataa gctatgcatg atttgcaatt cagtgtgtgt caggtctatg
    19981 gtttcttcat taaatttaag ctttgctgca tcaagtagta actcgcaatc atctactgtt
    20041 aaattattaa cttgagtggt gaaatcatac gtgcggcgta atagtgcttg aatcttagta
    20101 attgtaacag tcatattaaa tggctggttc tgttgcaaag taaaaaatat agctaatcac
    20161 taatatatca tgtcagtgtt cgtttaactt gctagcatga tgctaatttc gtggcatggg
    20221 gaaaatccgt agatctgaag agacctacgg ttctttttat atagagcgta aatacattca
    20281 atacctttta aagtattctt tgccgtattg atactttgat atcttgtctt tcttacttta
    20341 atatgacggt gatcttgctc aatgaggtta ttcagatatt tcgatgtaca atgacagtca
    20401 ggtttaagtt taaaagcttt aattatttta gccattgctg ccttcgttga aggtgcctga
    20461 tctgtaacta ccttttgagg cttaccaaat tgtttaatga gacgtttgat aaacgcatat
    20521 gctgaatgat tatctcgttg cttacgcaac caaatatcta atgtatgtcc ctctgtatca
    20581 atggcacgat ataaatagct ccattttcct tttattttga tatacgtctc atcaatacgc
    20641 catttgtaat aagctttttt atgctttttc ttccaaattt gatataaaat tggggcatat
    20701 tcttgaaccc aacggtagat cgttgaatga tgaacgttta caccacgttc tcttaatatt
    20761 tcagatatat cacgatagct caatacatat cttagatagt agccaacggc tacagtgata
    20821 acatccttgt taaattgttt atatctgaaa tagttcatac agaagactcc tttttgttaa
    20881 aattatatta taaattcaac tttgcaacag aaccgtattt tatgagtaca ctctaaatta
    20941 aggagatgta taatcaatct aaaattgtat ttttatactt ttgttatata atctttctac
    21001 ttagagatat attgtaaaaa aaccaacaaa atgttatatt aacattacta ttttatcgat
    21061 gaaggaggat taaaatgaca gcttctatga gactcaaata aacctttttg aatacaaaac
    21121 taaattaatt caaaaaggct tgtccgcaat acacactcat aggatgactt atgtcatttt
    21181 ttatccttcg ataggaataa taaacgcttt caaatactaa aacatcataa taaattttta
    21241 agtgtttgaa agtgtaatgt gaatgagacg ggagtagcct gtctcatttt tttgcgtaca
    21301 cgtcctttaa atatacaagg agtgtataaa tatggaacaa tatacaatta aatttaacca
    21361 aatcaatcat aaattgacag atttacgatc acttaacatc ggtcatcttt acgcttacca
    21421 atttgaaaaa atagcactta ttgggggtaa tggtactggc aaaaccacat tactaaatat
    21481 gattgctcaa aaaacaaaac cagaatctgg aacagttgaa acggttggcg aaattcaata
    21541 ttttgaacag cttaacatgg atgtggaaaa tgattttaac acgttagacg gtagtttaat
    21601 gagtgaactc catataccta tgcatacaac cgacagtatg agtggtggtg aaaaagcaaa
    21661 atataaatta gctaatgtca tatcaaatta tagtccgata ttacttttag atgaacctac
    21721 aaatcacttg gataaaattg gtaaagatta tctgaaaaat attttaaaat attactatgg
    21781 tactttaatt atagtaagtc atgatagagc acttatagac caaattgctg acacaatttg
    21841 ggatatacaa gaagatggca caataagagt gtttaaaggt aattacacac agtatcaaaa
    21901 tcaatatgaa caagaacagt tagaacaaca acgtcaatat gaacagtata taagtgaaaa
    21961 acaaagattg tcccaagcca gtaaagctaa acgaaatcaa gcgcaacaaa tggcacaagc
    22021 atcatcaaaa caaaaaaaca aaagtatagc accagatcgt ttaagtgcat caaaacaaaa
    22081 aggcacggtt gagaaggctg ctcaaaaaca agctaagcat attgaaaaaa gaatggaaca
    22141 tttggaagaa gttgaaaaac cacaaagtta tcatgaattc aatttcccac aaaataaaat
    22201 ttatgatatc cataataatt atccaatcat tgcacaaaat ctaacattgg ttaaaggaag
    22261 tcaaaaactg ctaacacaag tacgattcca aataccatat ggcaaaaata tagcgctcgt
    22321 aggtgcaaat ggtgtaggta agacaacttt acttgaagct atttaccacc aaatagaggg
    22381 aattgattgt tctcctaaag tgcaaatggc atactatcgt caacttgctt atgaagacat
    22441 gcgtgacgtt tcattattgc aatatttaat ggatgaaacg gattcatcag aatcattcag
    22501 tagagctatt ttaaataact tgggtttaaa tgaagcactt gatcgttctt gtaatgtttt
    22561 gagtggtggg gaaagaacga aattatcgtt agcagtatta ttttcaacga aagcgaatat
    22621 gttaattttg gatgaaccaa ctaatttttt agatattaaa acattagaag cattagaaat
    22681 gtttatgaat aaatatcctg gaatcatttt gtttacatca catgatacaa ggtttgttaa
    22741 acatgtatca gataaaaaat gggaattaac aggacaatct cttcatgata taacttaaaa
    22801 actatacact aatttatatt gaatattagg ttcatttata tcaatataaa aaatacgttc
    22861 acaagaaaaa tataatagaa ataaggatcc aataaaatga ctcgacataa tgaaattatt
    22921 aaatgtgcag aaaaatatca attacacatc caacctcaaa caatctcatt gaatgaatcg
    22981 ggacttgatt ttcaagttgc atttggaaaa gataaacatg gagtagaatg ggttttgaga
    23041 ctaccaagaa gacctgacgt ttataaacga acaaaacccg aaaaacaaac ggtagacttc
    23101 ttacagaaga atgtttcatt tgaaataccg aagtggaaag tacatgcaaa agaccttatt
    23161 gcttacccaa aacttacagg taaacccgca gccacaatag atccagaaat acaaaattat
    23221 gtatgggaaa ttgaacacaa accattacca gaaaacttta ttaacacatt agctgaaaca
    23281 ctcgtagatt tacacaacat accagaagaa aacattaacg ttcagcatat aaatatcaaa
    23341 accatacaag aaataaaaaa tgactttcaa agaagaatga ataaagttaa agaaacttat
    23401 ggcgtatcag atgaattatg gaacagatgg aaacaatggt tagaaaacga cgaactatgg
    23461 cctcgacatg cgaccatgat acatggggac ttacatccag gacatataat ggtagataac
    23521 caagcaaacg tcacaggtct catagactgg actgaagcaa cccactccga cccatcaatg
    23581 gactttatag gacaccatcg tgtattcgac gacgaaggat tagagcaact tataacagca
    23641 tacggtaaag ctggaggtga aatatggcca cgaatgaaag agcatataat agaactcaat
    23701 gcagtattcc caatgtttat cgctgagttt gctatggaat caggagaatc ggcgtatgaa
    23761 acgatggcat tgaaagagtt aggtatgaaa gagtagaact tatattaaaa gaggcccatt
    23821 ttaaagacga aggcaatcct gatgaaattt taaaactgcg tttaattagt gatggtcttt
    23881 ggttttctat aatgtattaa atatctggac atggaacaaa tgcaacaaat ggaaagaatc
    23941 gttttcgaaa tttctaactc cttaaatcag gaggataaat aaacggtcat tttcattgaa
    24001 agcacttata taaatttcat caattttaat acctaccgta aatacatttc ataagtatta
    24061 aacagatgat taaaattttt agttaattta aatatttatg atagagatga ccttcaaatg
    24121 aacggttctg ttacaaagaa aaaatctata tttattttta gtaagtttta attatagata
    24181 tgtacacttt gagtacaccc taaccataca aaaagaattg ttgaaattat aacaattaaa
    24241 acgtatgatt agggtgtata tttattatgg agtgaagatg aatgattata ggttatgcga
    24301 gagtatcatc gatagatcaa aatttagaaa gacaattgga taatttaaag acgtttggtg
    24361 tggagaaaat ctttacagag aaacagtcgg gaaagtcagt ggaaaataga cctgtatttc
    24421 aagaagcact caattttgtc agaatgggag atcgattcgt tgtggaatct attgatcgtt
    24481 taggacgtaa ctatgatgaa attattgaaa ctgtgaatta tttaaaagaa aaagacgttc
    24541 agttaatgat taccagctta cctatgatga atgaagtaat tggcaatcca ttactggata
    24601 agtttatgaa agatttaatc attcaaatat tagcaatggt ttcagaacaa gagagaaatg
    24661 aaagtaaacg tcgacaagcg caagggattc aagttgcgaa ggaaaaaggc gtatataaag
    24721 ggcgcccttt actttattca ccaaatgcta aagacccaca gaaacgtgtt atttatcatc
    24781 gcgtggtgga aatgttagaa gaaggcaaag cgattagtaa gattgcgaaa gaagttaata
    24841 tcacaagaca aacagtttat agaattaaac atgataaggg attatcttga taaattgatt
    24901 gtcaatgcaa atgagcgtct ctcacagtgt ctcaaattcc ataacatatt attgaattga
    24961 gattttaata attatacaag aaaaaagagt acgagttcgc agctttctat atagtaattg
    25021 ttttactaat aaggtgtttt aaaatatatt ataatgtaaa aagtatttga catttgtatc
    25081 aaaaatattt acactcataa atgtcaaata ctttttacat ttatgaggtg ttataatgaa
    25141 tttaattcct tttattatta ttttaatttt ttcttgttta tggacggcta taactaacaa
    25201 atatttacct tcagaaacat tagataaaaa aggacaacaa gatcgatacg atgaaagaca
    25261 acgtaaaatg tttattgaaa tactggctaa aagttttatt tggattgtat attgtatgtt
    25321 atttacacta gtgcttaaat ttacaggttt gtcaccaagt attgaaggat cttggttttc
    25381 tcaatatcca gaaattttct ttataattgt agcactattt cttatgctgt ttaattacta
    25441 tactacaaat aaaaaatata catctaaagg ttaaattaat gaaaaataga attagagaat
    25501 atagaaaaca aaaaggaatt tctcaagaaa ctttaagtaa agaattaaaa gtgtctaggc
    25561 aaactattaa tgcaatagaa aacaataaat atgatcctac attgacatta gcatttaagt
    25621 tggcaagatt gtttgataca actgtggatg aattattttc ttaaccattc atttatcaca
    25681 aaaagagagt gcgaattcgc actctctttt tgtgtagtag tactattaaa ttttgtctca
    25741 ataacgaacg tttataacgc aatcatgatg agagtattaa tacagttaat tatttgaaat
    25801 actttagttt acataatcga tgattaccag aagttctcac tatataaaag acactaaaat
    25861 tttataactt ttagtgccta atcaattatt ttagctacca aacaaacgac tccaaaaccc
    25921 ctttttaggt tccgtttctt cactcttttc ttctatatca ctatcattgt catttagatt
    25981 agctggaacg tcttcttttt ttgcttcttc accttgtgta ctttcgtcgc tttgacttcc
    26041 agatatatcc ttatattgaa tctctgtttc tttagtttct tcctgatctc tgttaatatt
    26101 tacaggatta gtagtatatg ttttttcttg tgcatcaacg ttttgtctag tgttagtaga
    26161 tgtatcaaag ggataattaa ggtgtttttc tttttctaat tgattttcta atttttgaat
    26221 ctttttatta ctctctaatg ccagaacttg ctgattttca agcaattttg atctttcttg
    26281 caactctttt ctgtaaaatt caattgttgt ttcatgacga ctttcttgtt tttcaatttg
    26341 attatttaaa gtatcaatct gatttttaag gatttctact atttgagcat cgcttttcga
    26401 ttcaaaatta atattatccg accctttttt ttgtttgtct tcagtagtac tttcaaaacc
    26461 atatttcttt ttattttcat ttactctttg aatgattttt tctatatcgg tatcttcttt
    26521 aataaacgaa gtgttttcct gttttattgt ctctatattc aatcgcttaa tattattaaa
    26581 aatcgtttgc ttactaaccc ctaattcttc actcaacttt ttcacacttt tcatatcatc
    26641 aaccctttat aaaatgttta taaacccttg ataaaatatt ataagcttat aatgcttaat
    26701 aataaagtga ttaataaata aaaataaaca tccatcaacc tttttatcaa gggtttatga
    26761 aaggtttatg atatttatca agggtttata aacccttgat aaagctatat tttccctttt
    26821 ataagtttat ttaaagtgct ataataaact taatataaca aaaaccccaa ctactggtaa
    26881 tagtcggggt ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt
    26941 gtattatata atgaataata tcttagtgca agcacctaaa tcattaaata aatgtaaagc
    27001 taaataaaaa cgttttatta cctcttacca aactaaaata tggaaagagg ttttttgtc
//
