LOCUS       NC_018957              26972 bp    DNA     circular CON 04-MAY-2024
DEFINITION  Staphylococcus aureus plasmid p18807-P03, complete sequence.
ACCESSION   NC_018957
VERSION     NC_018957.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224396
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 26972)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Complete nucleotide sequence analysis of plasmids in strains of
            Staphylococcus aureus clone USA300 reveals a high level of identity
            among isolates with closely related core genome sequences
  JOURNAL   J Clin Microbiol 48 (12), 4504-4511 (2010)
   PUBMED   20943864
REFERENCE   2  (bases 1 to 26972)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2010) Laboratory of Human Bacterial Pathogenesis,
            Rocky Mountain Laboratories/NIAID/NIH, 903 S. 4th Street, Hamilton,
            MT 59480, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009947995.2-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 03:41:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 32
            CDSs (total)                      :: 32
            Genes (coding)                    :: 25
            CDSs (with protein)               :: 25
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 7
            CDSs (without protein)            :: 7
            Pseudo Genes (ambiguous residues) :: 0 of 7
            Pseudo Genes (frameshifted)       :: 3 of 7
            Pseudo Genes (incomplete)         :: 4 of 7
            Pseudo Genes (internal stop)      :: 2 of 7
            Pseudo Genes (multiple problems)  :: 2 of 7
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26972
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="18807"
                     /db_xref="taxon:1280"
                     /plasmid="p18807-P03"
     gene            1..984
                     /locus_tag="HS349_RS00005"
                     /old_locus_tag="SUD_0001p2"
     CDS             1..984
                     /locus_tag="HS349_RS00005"
                     /old_locus_tag="SUD_0001p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1004..1293
                     /locus_tag="HS349_RS00010"
                     /pseudo=""
     CDS             <1004..1293
                     /locus_tag="HS349_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1492..1872)
                     /locus_tag="HS349_RS00015"
                     /old_locus_tag="SUD_0003p2"
     CDS             complement(1492..1872)
                     /locus_tag="HS349_RS00015"
                     /old_locus_tag="SUD_0003p2"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2157..2849)
                     /locus_tag="HS349_RS00020"
                     /old_locus_tag="SUD_0005p2"
     CDS             complement(2157..2849)
                     /locus_tag="HS349_RS00020"
                     /old_locus_tag="SUD_0005p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2959..3153
                     /locus_tag="HS349_RS00025"
                     /old_locus_tag="SUD_0006p2"
     CDS             2959..3153
                     /locus_tag="HS349_RS00025"
                     /old_locus_tag="SUD_0006p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4269..4886
                     /gene="cadD"
                     /locus_tag="HS349_RS00030"
                     /old_locus_tag="SUD_0009p2"
     ARG             4270..4883
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4905..5252
                     /locus_tag="HS349_RS00035"
                     /old_locus_tag="SUD_0010p2"
     CDS             4905..5252
                     /locus_tag="HS349_RS00035"
                     /old_locus_tag="SUD_0010p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5409..5501
                     /locus_tag="HS349_RS00040"
     CDS             5409..5501
                     /locus_tag="HS349_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5673..6644)
                     /locus_tag="HS349_RS00045"
                     /old_locus_tag="SUD_0011p2"
     CDS             complement(5673..6644)
                     /locus_tag="HS349_RS00045"
                     /old_locus_tag="SUD_0011p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6768..7187
                     /locus_tag="HS349_RS00050"
                     /old_locus_tag="SUD_0012p2"
     CDS             6768..7187
                     /locus_tag="HS349_RS00050"
                     /old_locus_tag="SUD_0012p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7713..8558)
                     /gene="blaZ"
                     /locus_tag="HS349_RS00055"
                     /old_locus_tag="SUD_0013p2"
     ARG             complement(7717..8558)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8665..10422
                     /gene="blaR1"
                     /locus_tag="HS349_RS00060"
                     /old_locus_tag="SUD_0014p2"
     ARG             8666..10419
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10412..10792
                     /gene="blaI"
                     /locus_tag="HS349_RS00065"
                     /old_locus_tag="SUD_0015p2"
     ARG             10413..10789
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11056..11634
                     /locus_tag="HS349_RS00070"
                     /old_locus_tag="SUD_0016p2"
     CDS             11056..11634
                     /locus_tag="HS349_RS00070"
                     /old_locus_tag="SUD_0016p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            12209..12883
                     /locus_tag="HS349_RS00075"
                     /old_locus_tag="SUD_0018p2"
     CDS             12209..12883
                     /locus_tag="HS349_RS00075"
                     /old_locus_tag="SUD_0018p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13052..13623)
                     /locus_tag="HS349_RS00080"
                     /pseudo=""
     CDS             complement(13052..13623)
                     /locus_tag="HS349_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(13899..14693)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HS349_RS00085"
                     /old_locus_tag="SUD_0021p2"
     ARG             complement(13903..14693)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14786..15316)
                     /gene="sat4"
                     /locus_tag="HS349_RS00090"
                     /old_locus_tag="SUD_0022p2"
     ARG             complement(14790..15316)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15313..>15948)
                     /locus_tag="HS349_RS00095"
                     /pseudo=""
     CDS             complement(15313..>15948)
                     /locus_tag="HS349_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16089..16763)
                     /locus_tag="HS349_RS00100"
                     /old_locus_tag="SUD_0025p2"
     CDS             complement(16089..16763)
                     /locus_tag="HS349_RS00100"
                     /old_locus_tag="SUD_0025p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16820..16996)
                     /locus_tag="HS349_RS00105"
                     /old_locus_tag="SUD_0026p2"
                     /pseudo=""
     CDS             complement(<16820..16996)
                     /locus_tag="HS349_RS00105"
                     /old_locus_tag="SUD_0026p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17010..17747)
                     /locus_tag="HS349_RS00110"
                     /old_locus_tag="SUD_0027p2"
     CDS             complement(17010..17747)
                     /locus_tag="HS349_RS00110"
                     /old_locus_tag="SUD_0027p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17740..18668)
                     /locus_tag="HS349_RS00115"
                     /old_locus_tag="SUD_0029p2"
                     /pseudo=""
     CDS             complement(17740..18668)
                     /locus_tag="HS349_RS00115"
                     /old_locus_tag="SUD_0029p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18784..19665)
                     /locus_tag="HS349_RS00120"
                     /old_locus_tag="SUD_0030p2"
                     /pseudo=""
     CDS             complement(18784..19665)
                     /locus_tag="HS349_RS00120"
                     /old_locus_tag="SUD_0030p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19662..>20039)
                     /locus_tag="HS349_RS00125"
                     /old_locus_tag="SUD_0031p2"
                     /pseudo=""
     CDS             complement(19662..>20039)
                     /locus_tag="HS349_RS00125"
                     /old_locus_tag="SUD_0031p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20097..20771)
                     /locus_tag="HS349_RS00130"
                     /old_locus_tag="SUD_0032p2"
     CDS             complement(20097..20771)
                     /locus_tag="HS349_RS00130"
                     /old_locus_tag="SUD_0032p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21245..22711
                     /gene="msr(A)"
                     /locus_tag="HS349_RS00135"
                     /old_locus_tag="SUD_0033p2"
     ARG             21246..22708
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22810..23709
                     /locus_tag="HS349_RS00140"
                     /old_locus_tag="SUD_0034p2"
     CDS             22810..23709
                     /locus_tag="HS349_RS00140"
                     /old_locus_tag="SUD_0034p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24195..24803
                     /locus_tag="HS349_RS00145"
                     /old_locus_tag="SUD_0035p2"
     CDS             24195..24803
                     /locus_tag="HS349_RS00145"
                     /old_locus_tag="SUD_0035p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25049..25387
                     /locus_tag="HS349_RS00150"
                     /old_locus_tag="SUD_0036p2"
     CDS             25049..25387
                     /locus_tag="HS349_RS00150"
                     /old_locus_tag="SUD_0036p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25392..25577
                     /locus_tag="HS349_RS00155"
                     /old_locus_tag="SUD_0037p2"
     CDS             25392..25577
                     /locus_tag="HS349_RS00155"
                     /old_locus_tag="SUD_0037p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25804..26547)
                     /locus_tag="HS349_RS00160"
                     /old_locus_tag="SUD_0038p2"
     CDS             complement(25804..26547)
                     /locus_tag="HS349_RS00160"
                     /old_locus_tag="SUD_0038p2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22811..23706
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21246..22711
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22811..23709
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(14787..15304)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15611..15912)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7714..8558)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1350..1497
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..984
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1116..1285
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25805..26547)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa agggttagaa aacgatggtc tactcattca aaaacgacgt
      301 ggtttaaata aaccaaatat tctatattta atgaaaccta ttgtcacaga acgtgatatt
      361 tacaaaatag aaaaagaaga aaacgatgtt gaaccttacg gcgagaagga agttcgaaaa
      421 tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acgtccagaa
      481 gttcgaaaat cgaacactaa tgatactgac tttaatgaca ttgactttaa tgatactgag
      541 aataatgata tgaatgactt gaatgatata aagtacaaaa atgaaattag taatcattca
      601 aatcattcaa atcaatttac acataatttt gatgataaag aaatgctatt gcaagaattc
      661 ccagaacaac taactaatta tttattaaaa tatgattata gagatttaga aatcataaag
      721 gctgttattc ttaaagcaaa aaaatcattt aattcaaggc atgaagatat gcattacatg
      781 ttagaggaca ttgaggatga aatattaact tctttaaaaa gacttaaaaa agctatacat
      841 gataggggag ttaaaggcca aaaggaaaca atcaagtcaa tgcaagctta tttaatgcaa
      901 acaattctaa ctgaacttga agaaacacat gccctttata tgcgccgtaa aaacatgaaa
      961 caatataata tctttaatca ataattcaaa tgattttata acactcgaag agacatcaaa
     1021 atattccgtt aaatcatctg actttttaac tgatgacgac gaaaaaaatc aagaaattgt
     1081 aagtgattta gaaaaaggtt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa
     1141 acaaaagcat aaaattttaa acttagacga tgccgaagat ggtaatttga ttaatacaag
     1201 tgatgaagat aaaacgacag acgaagaaaa aaagcacatt caattaccgc aatttggaat
     1261 ttcgaaaagc aaaattatta tttaagacat tagtgataac tgatgtcttt ttttattgtt
     1321 tttctgtaaa aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag
     1381 tgtgacacta cagctttgta tgatatcact ttaaaataac ttaaaaccct tggaatgtct
     1441 ggccttgcca gatctatcat ttttgaatga tagcaaattt cccttatgct cttacggaga
     1501 ttttagagtt aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga
     1561 aaaacatggg gaagttttaa agtattttat gctaattttt aaatttgcat gtaaatgggc
     1621 agtatctaaa aaattagtca ctgattttgc tgaaattttt gtttgtgaaa ttagcatata
     1681 tttatttggc tcatatttgc gttttaagag actgtataga tttttaagta caaaacctat
     1741 atgatttgcc tctaagtctt caaaatgcct cttaaaatcc aaaataaaag tgtttaatat
     1801 tgtaataagg attgctattt ttataaaagg agagatatca tgaagattaa aactttcgct
     1861 acttttactc atcgtcaatt agataaacaa gttaataggt ttttaaagaa tgatattcat
     1921 gtattagaaa ttcaaacaca cagtaattgg ttatatattt cagctattgt tttttatgag
     1981 gataaataag gaacatcgta tttatgccga aaaaatttat tgatgttgag aagaaccctt
     2041 aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag
     2101 ttttgggatt gttaagggtt ccgaggctca acgtcaataa aacaattgga ataaaatcaa
     2161 cctacagagc atccagctgc aaatgcagtt ccgcaaactg cttcacatac accgccggct
     2221 attggattta cgattgccca tactccacag tagtgagcac atgcataaag tccagccata
     2281 ctacaagcga atgctttgcc gttccatttg aatcctgcat atgttaccgg tctgttttta
     2341 tcaacttttt cagccttata ttcaacgtaa tttttgttaa taagtatttt tccctctttg
     2401 ttttcagtca tacttctttt ttcggcaatg aattttgtga tttttttgtt gtagttatca
     2461 tatattgttt cagaaactac aatttctttt gttttttcat ttttataagc gttattagct
     2521 atgtagccat atgcattttt atcatttgct tctgtagcta gatattttaa tttagaattt
     2581 ttgtcttcta gctttatttt tttaaatcct tcttttttca tttgcttttc gaatttttgc
     2641 atatcttcat ttttattttg caattgttct agaaaactta tttctttctt ggtcatttgt
     2701 gatacttcga tgtttttgct tttcaatttt tctttttgat tttctagtaa agaacttttt
     2761 tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa ataccagtag gaacaaggaa
     2821 attattgaaa ataattttat aattttcatt tgatacctcc aagataataa gatattttaa
     2881 ttgtataagt aagcgcttta taaaatcaat atttatttta atatatttat aaacatattt
     2941 ttgaaaggag tctattttat gaatgaaaat ttagaaaaat atataaaaag tttgccactt
     3001 ttaggtttgt taattagtat tttgttaatt gttttattct tttttatttt agatgttgat
     3061 gaagatttat tcgtggtttt tttatactgt ttattgcctt tgatagttaa tttgtctatt
     3121 tatggttttt atgtttttgt taaaagaaag taagattatg aataattttg tttttaattt
     3181 gtatgctttg agggggttgg aaaacggtag gtgtatagat tagatttctt gtttttttga
     3241 aacgagtgtg aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt
     3301 tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg
     3361 ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat
     3421 atttatttgg ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata
     3481 tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat
     3541 aaaagctacc ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct
     3601 ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt
     3661 tttcaagaat gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc
     3721 tcaagccgtt tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca
     3781 catgtcgatt tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac
     3841 gaattttaga cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaag
     3901 tagaaccgaa aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact
     3961 tcctaaaact gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt
     4021 gtctccatgt ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag
     4081 aacccttaac taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt
     4141 cgacaagttt tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata
     4201 aagcacctat gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga
     4261 ggtgtattat gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg
     4321 atttattagt aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag
     4381 atatttatgt tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4441 cttttgtatt aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa
     4501 tttatcttgg aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa
     4561 aagaattgaa tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag
     4621 caagttgtgg cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta
     4681 ctaatttatt acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg
     4741 cacaaaaatt agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga
     4801 ttatggctat tatttatata gctttaggtt tatttattat tattgaaaat gacactattc
     4861 aaacaatttt aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata
     4921 cttgtgatgt gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag
     4981 atgataaatc taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga
     5041 aaatcatatt atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat
     5101 tgaaaatgag tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac
     5161 ttgattttta taaagatgga aagatggcat attattttat taaagacgat gaaataagag
     5221 agtttttctc taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat
     5281 aaaaaacaaa gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca
     5341 cagatggtat aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt
     5401 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     5461 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     5521 gccagcatcg aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt
     5581 taatcatttt cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa
     5641 ttaatagtaa atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa
     5701 tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg
     5761 tatagaagtg aatttcctat attccattca tttgctaact tactccatat atcttcacgg
     5821 atattatgat caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac
     5881 ggtaatatat tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct
     5941 tgataattta gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa
     6001 taatcaaaaa tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt
     6061 gcacctaatt tttttgcgat ttctatttgc ttttcttttc ttacgatagc agtgatattt
     6121 tcatatccaa ttttatgtaa aatttgtata gcaacactgc ccacaccacc tgtagcccca
     6181 gacactaaaa tttcaggttg tgatttgata ttcattccat atttttctag ttcaaaaatt
     6241 gataatgctg ccgtaaaacc ggctgtgcca tataccatag actctttaat agacatttct
     6301 tggggaatag gaacaatcca ctctccaggc acttgtgcat attctgaaaa tccacctgta
     6361 tgtgtcacgc caacatcata accagtaact aatacattat cgccttcttt aaacttatca
     6421 ttcgaacttg attcaacaat acctgcaaaa tctataccag gaatcatagg ataatctcta
     6481 attacaccgc ctttatattg taaagctagc atatccttat aatttattga agagtatacc
     6541 acttttacta atacatcacc cttcgataaa tgagattcat caactttttc tactttataa
     6601 ctaacatttg atgcactttt tctcactact accgcattga acatttatta gccttctttc
     6661 acaattgttt tgtagaagta tgtttttgtt gcaaaactat tttcctacaa aacttatcat
     6721 gatatgataa gcgagtcaat actaatgatt taagagaggt tttagttgtg gaattagata
     6781 attgtataaa ttatttgttg agtacttctc agaatagagt ttttaaacat tttaaaagtt
     6841 tattaagtcc ctataatatt actccagcag aatatggtgt tttgaattgc ttgattaata
     6901 gtaatttgaa tacacctaaa gcgattggta atactttaaa tttagaacct tcaacaatat
     6961 ctggaatatt agataagatg tccaaaaagg atctaataac acgtcaaact gataatgaaa
     7021 atagaagaac tgtgctaata aacagtacaa ataaagcaaa agacttatgg ccaacattag
     7081 aaaagaaagc ctatcaactt aataatcatt acttcgctaa tttaactaat gaagaaactg
     7141 tagtgtttaa aaagatatta ctaaagataa ataaaactac gttttaattt ttacgttata
     7201 aaaaagttga agtgcgaatt ataatcgagt aaatataaat gatagcttag cttaattata
     7261 tattaaagcc aactatactt ttattcccga aaaacctact atccaaattt ctaagatact
     7321 ttagcctcta taataaacat attgtaatat aatttatgta ttatttaggt ttaccctaat
     7381 cgaacaataa aaaatacttg taaaatgcta ttgtcacttt gcttgatata tgagaattat
     7441 ttaaccttat aaatgagaaa aaagcaacgc actttaaata agatacgttg ctttttcgat
     7501 tgatgaacac ctataattaa actattcatc tattatttat gattttttgt atatacaata
     7561 tttctagttt gttaaagaga attaagaaaa taaatctcga aaataataaa gggaaaatca
     7621 gtttttgata tcaaaattat acatgtcaac gataatacaa aatataatac aaactataag
     7681 atgttatcag tatttattat gcatttagaa tattaaaatt ccttcattac actcttggcg
     7741 gtttcactta tcaacttatc atttggctta tcacttttat tgtctttatt cgtaaaaatg
     7801 actaaaacaa taggttcaga ttggccctta ggataaacaa aagcaacatc atttctagaa
     7861 gcatatgtta ttgcttgacc acttttatca gcaaccttat agtcttttgg aacaccatct
     7921 ttaattaaag tgtctccgtt tttattatta aacattaaat caagtaagaa atttttattt
     7981 tttttgctta attttccatt tgcgataagt ttatttaaag tcttgccgaa agcagcaggc
     8041 gttgaagtat cttttttgct ctttggtgaa tagtaattta attctatctc atatctaact
     8101 ggatttgtta ctttatctcc tagttctttt agacgttgtt taactttttt gattccaccg
     8161 atttctttta taattttatt gtttgctgta ttatcactat atgtcattga agcctcaata
     8221 agttctttta aagtgatatc ttttcctaca tatttttcta aaataggaga ataagcaact
     8281 atatcatctt tgttaatatg tactttttta tttaacttat tataaggtac ttgttctaac
     8341 aaaatagcac tatttatcgc ttttgaagtc gaagcatagg caaatctctt atctgaatta
     8401 aattttactt ccttaccact tttagtattt aaagcataaa caccaatatg agcattatat
     8461 tttttttcta aatcatttaa ctctttggca tgtgaactgt ttgaattaca tgcacttaaa
     8521 actaaagcaa ttacaattaa aaatattaac tttttcaaaa taaaccctcc gatattacag
     8581 ttgtaatttt tataaatcaa taatattaca attgtaatat tgatgtcaat tgtttattat
     8641 aaatatttga aagaaggtgt caaaatggct aaattactaa taatgagcgt agtaagcttt
     8701 tgttttatat ttctattgtt agtatttttt aggtacatat taaaacgcta ttttaattat
     8761 agtttaaatt ataaagtttg gtatctaact atgcttgctg gattaattcc ttttatccca
     8821 attaaattct cttttataaa atttaataat gtgaataatc aagcgcccac agttgaaagt
     8881 aagtcacacg atttgaacca taacataaat accaccaaac ctattcaaga gttcacaaca
     8941 gatatccata agtttaattg ggattcaatt gataatatct gcacagttat ttggatagtt
     9001 ttagttatta ttttaagttt taaatttttg aaagccttat tatatcttaa atatttaaag
     9061 aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa tagatacgat acttttcaac
     9121 catcaatata aaaaaaatat tgtgattcga aaagcagagg ctattcaatc tccaataact
     9181 ttttggtatg ggaaatatat tattttgatt cctagttcat attttaaaag tgtaattgat
     9241 aaaagactaa aatatataat actgcatgaa tatgctcatg ctaaaaatag agatacttta
     9301 catttaatta tctttaatat cttctctatt attatgagtt acaatccatt agtacatatt
     9361 gtaaaaagaa agataattca tgacaatgaa gtagaagccg atagatttgt ccttaataat
     9421 attaacaaaa atgaatttaa aacttatgcg gaatctatta tggactccgt attaaaaacc
     9481 ccattttcca acaaaaatat attaagccat tcatttaatg gtaaaaaatc attactcaaa
     9541 agtagattaa ttaatataaa agaagccgat ctgaaaaagc agtcaaaatt aattctaatt
     9601 tttatttgta tttttacttt ttttatcatg ataattcaaa gccagttttt aatggggcaa
     9661 tccttaactg attataatta taaaaagccc ttacaaagcg attaccaaat tttagatgaa
     9721 agtaaaaatt ttggttcaaa tagtggatct ttcgttatgt acagcatgaa gaaagacaaa
     9781 tactatattt ataatgaaaa agaaagtaga aaaagatatt ctcctgattc aacttacaaa
     9841 atttatttag cactgtttgg acttgaccgt catattataa gtgataaaaa ttcacgtatg
     9901 tcatggaatc ataaacatta tcttttcgag tcttggaata aggaacaaga tttaaataca
     9961 gcaatgcaaa attcagttaa ttggtacttc gaacgtatta gtaatcaaat accaaagaac
    10021 tatactgcgg ctcaactcaa gcaattaaat tatggtaatg aaaatttggg aagttataaa
    10081 agctattgga tggaagatag tttgaaaata tctaatcttg aacaagtaat agtttttaaa
    10141 aatatgatgg aacaaaataa ccattttagt aaaaaagcaa agaatcaatt atcttcttca
    10201 ttattgatta agaaaaatga aaagtatgaa ctgtatggga aaacaggtac aggtatagta
    10261 aacgggaagt ataataatgg gtggtttgta ggttacgtaa ttacaaatca tgataagtat
    10321 tattttgcta cacatttatc agatggaaac ccgtctggga aaaatgctga attaataagt
    10381 gaaaaaatat taaaaggaat gggtgtttta aatgaccaat aagcaagttg aaatatctat
    10441 ggctgaatgg gatgttatga atataatatg ggataaaaaa tcagtatcag ctaatgaaat
    10501 tgtagttgaa attcaaaaat ataaagaagt tagtgataaa acgattagaa cattaatcac
    10561 aagactatat aaaaaagaga ttataaaacg atacaaatca gaaaatattt atttttactc
    10621 atcaaatatt aaagaagacg atattaaaat gaaaactgct aaaacctttc ttaataaact
    10681 gtatggaggg gatatgaaaa gtttagtgct gaattttgcg aaaaatgaag aattaaataa
    10741 caaagaaatt gaagaattgc gagacatttt aaatgatatt agtaaaaagt aattagaggt
    10801 atgtttcaaa cataatacat atgtaaacca tacttgactc ttattaaatt agttttgtta
    10861 atgacattta aaatatatta ttaaagatga gagtgtccag aaaataacca ttttctgtac
    10921 actcttgttt tttgtctaaa taagtaagta ttacatagaa ttatgtgttc aaaaacccaa
    10981 caaaaaatct atgttcacaa aagacctcgt aatcaagtta tggtacacta aaggtgtata
    11041 taggaggtct gtattttgaa aataggttat gcaagagttt caactggatt acaaaatttg
    11101 aatttacagg aggatcgatt aaatacatat ggttgtgaaa agatatttaa tgaccatatg
    11161 agtggttcaa aaagtaagcg acctggttta gataaagcaa ttgaatttgc gaggtcagga
    11221 gatacgattg ttgtttggag attagataga ctaggacgga acatggagga tttaatcacg
    11281 ttagttaatg aacttaacga acgaggtgtg agttttcata gtttagaaga aaatataacg
    11341 atggataaat caagttctac aggacaatta ttatttcatt tattcgcagc atttgcagag
    11401 tttgaacgta atttaatttt agagcgatca tcagccggtc gaattgcagc acgtgctaga
    11461 ggccgatatg gaggtagacc tgaaaaatta aataaacaag atttaaactt acttaagaca
    11521 ctttatgata atggtacgcc aattaaaaca attgcagagc agtggcaagt ttcacgtaca
    11581 actatttatc gttatctcaa taaattagag gcaaaagaga ataaaaacaa gtagagcaac
    11641 taatctagct tactataatg aatctactaa ataattttat atatcattaa catacaaaga
    11701 ctttgattca atgtcactcg atgtaaaaga gacgttctga cagcgtctaa aatctcataa
    11761 tattttcctg ttatgagatt ttaataataa cacaagaaaa aagcgtacaa attcgtacgc
    11821 ttttttaata taatacctgt ttcactaatg aacgttttaa gtatcttcat cattaactga
    11881 aactacagta ataatactcg tcaacaatat tagtatagtt aaaatagaaa gacttaggac
    11941 tggcataacc gaactaaaat tatatttgaa atataaaagt gctaatgaag agagaaatgt
    12001 aaaaataata aataccaaag accatttttc taatttattc attggcttca cctctttgaa
    12061 cttttatata atcataggag atatttttac tacgatttat aaaaaataag aagataatca
    12121 ttattaaaga aacgattaat ataatgttga atggttctgt tgcaaagttg aatttatagt
    12181 ataattttaa caaaaaggag tcttctgtat gaactatttc agatataaac aatttaacaa
    12241 ggatgttatc actgtagctg ttggctacta tctaagatat gcattgagtt atcgtgatat
    12301 atctgaaata ttaagggaac gtggtgtaaa cgttcatcat tcaacggtct accgttgggt
    12361 tcaagaatat gccccaattt tatatcaaat ttggaagaaa aagcataaaa aagcttatta
    12421 caaatggcgt attgatgaga cgtacatcaa aataaaagga aaatggagct atttatatcg
    12481 tgccattgat gcagagggac atacattaga tatttggttg cgtaagcaac gagataatca
    12541 ttcagcatat gcgtttatca aacgtctcat taaacaattt ggtaaacctc aaaaggtaat
    12601 tacagatcag gcaccttcaa cgaaggtagc aatggttaaa gtaattaaag cttttaaact
    12661 taaacctgac tgccattgta catcgaaata tctgaataac ctcattgagc aagatcaccg
    12721 tcatattaaa gtaagaaaga caaggtatca aagtatcaat acagcaaaga atactttaaa
    12781 aggtattgag tgtatttacg ctctatataa aaagaaccgc aggtctcttc agatctacgg
    12841 attttcgcca tgccacgaaa ttagcatcat gctagcaagt taagcgaaca ctgacatgat
    12901 aaattagtgg ttagctatat ttttttactt tgcaacagaa ccagcatttg ttttaatatt
    12961 tgttccaaag agccatcatg gctttgacag agctcttctt ctatgcaaat gcttttaatc
    13021 cgatccacac gaaaattcct atattcattt cttagcctgc aaaaccgatt aagtaccagt
    13081 tctgttcata aaaccccagt gatataggct ctatcattct gctttccggt tcttgccctc
    13141 ctgatgcagg atattgaatt gatattaccc ttttattgca gattgcagtc tgaattgctg
    13201 caataacgtt atccgccaat gtatttttct gtccagatgt gctgtacacg ttaatactgt
    13261 tctccaactc ctgtgcatag tttttttcac catgcttcaa aatagatttg attttataca
    13321 tagctgaatc aaaatccttt ataaatgatt catctccatg gcaatttaaa aatttccctg
    13381 ctgtaatcaa tgcacccact tccgccgctg taaacattac cggcagaagt aggaagccct
    13441 ctacaagaaa atatcctttt ccggcctcag atccaattgg tattccggct tcttcaagtg
    13501 tccggatatc tctgtaaact gtccttaagc ttatattaaa tcgctgtgca atttctttgg
    13561 caggaattat ttttttgatt gcagctgaat aagaatagag gttactctgt taatcctgtt
    13621 caaattttat tcctcctctg tgacttccat aaaaagtata tcctatgcgt tcttaagcta
    13681 gctgctgtta gtgcttctca ttgcaccctg gttataaaag ccatactcac aaacctcttc
    13741 accaaaactc tttacatctc taatatagaa ctctatctag cgaactttta gaaaagatat
    13801 aaaacatcag agtatggaca gttgcggatg tacttcagaa aagattagat gtctaaaaag
    13861 cttgtagtta aagcttttta gacatctaaa tctaggtact aaaacaattc atccagtaaa
    13921 atataatatt ttattttctc ccaatcaggc ttgatcccca gtaagtcaaa aaatagctcg
    13981 acatactgtt cttccccgat atcctccctg atcgaccgga cgcagaaggc aatgtcatac
    14041 cacttgtccg ccctgccgct tctcccaaga tcaataaagc cacttacttt gccatctttc
    14101 acaaagatgt tgctgtctcc caggtcgccg tgggaaaaga caagttcctc ttcgggcttt
    14161 tccgtcttta aaaaatcata cagctcgcgc ggatctttaa atggagtgtc ttcttcccag
    14221 ttttcgcaat ccacatcggc cagatcgtta ttcagtaagt aatccaattc ggctaagcgg
    14281 ctgtctaagc tattcgtata gggacaatcc gatatgtcga tggagtgaaa gagcctgatg
    14341 cactccgcat acagctcgat aatcttttca gggctttgtt catcttcata ctcttccgag
    14401 caaaggacgc catcggcctc actcatgagc agattgctcc agccatcatg ccgttcaaag
    14461 tgcaggacct ttggaacagg cagctttcct tccagccata gcatcatgtc cttttcccgt
    14521 tccacatcat aggtggtccc tttataccgg ctgtccgtca tttttaaata taggttttca
    14581 ttttctccca ccagcttata taccttagca ggagacattc cttccgtatc ttttacgcag
    14641 cggtattttt cgatcagttt tttcaattcc ggtgatattc tcattttagc catttattat
    14701 ttccttcctc ttttctacag tatttaaaga taccccaaga agctaattat aacaagacga
    14761 actccaattc actgttcctt gcattctaaa accttaaata ccagaaaaca gctttttcaa
    14821 agttggcgta taacatagta tcgacggagc cgattttgaa accacaatta tgatagaatt
    14881 tacaagctat aaggttattg tcctgggttt caagcattag tccatgcaag tttttatgct
    14941 ttgcccattc tatagatata ttgataagcg cgctgcctat gccttgcccc ctgaaatcct
    15001 tacatacggc gatatcttct atataagcgt accggttcca attttttcgc agtttaactt
    15061 ttccgacgca tttatcgtct tggtagtaaa gatatattat cttatcagta ttgtcaatat
    15121 attcaaggca atctgcctcc tcatcctctt catcctcttc gtcttggtag ctttttaaat
    15181 atggcgcttc atagagtaat tctgtaaagg tccaattctc gttttcatac ctcggtataa
    15241 tcttacctat cacctcaaat ggttcgctgg gtttatcgat atctttcagg tgccctgctt
    15301 tcatttctgt aatcactgtt cccgcctctc ttctatatca gcggcatatg tgctatccag
    15361 gcagccggtt ttaccagtgt attttttata catgtccctg gtatattttg ttatattcct
    15421 atcatactcc ggataggcat aatgaagcct ttccgccacc tcaccggata ccgccctgaa
    15481 caattgatgg catagaaata atgcttccca tatgttttca taggaatcca tccggtaggt
    15541 ggacaaaagt ttctcccaca aatcctcgga tatatacctt tcaataaact tatagttctt
    15601 gcctacactt catttaaagc ctgtttcgat gccgaccttc catgatatca ttctcagcag
    15661 ctcatggcga acaatctgat taaaatgatc aatagcaaat aaaatttcct tacggcacaa
    15721 tcctttaata acataaggtg ttacattcca aaattcattg cagcaatcat catactccct
    15781 tgcgcttggc tttcttacat gataatctat atcagtcgga actatgtccc ttttaattct
    15841 acaatcttta tcaattagaa cctttattaa tttatcgccc tttaggtaat tatctaactc
    15901 ttccaagggc aataaggtaa gatcaatttt attgtaatca tcaaatagct ataatagatt
    15961 tagaggtaaa gaaattaaat acattgaaga gcagaaagat tttacaaaag agtattttaa
    16021 taaaaatgat ggttctgttg caaagtaaaa aatatagcta atcactaata tatcatgtca
    16081 gtgttcgttt aacttgctag catgatgcta atttcgtggc atggcgaaaa tccgtagatc
    16141 tgaagagacc tgcggttctt tttatataga gcgtaaatac actcaatacc ttttaaagta
    16201 ttctttgctg tattgatact ttgatacctt gtctttctta ctttaatatg acggtgatct
    16261 tgctcaatga ggttattcag atatttcgat gtacaatggc agtcaggttt aagtttaaaa
    16321 gctttaatta ctttaaccat tgctaccttc gttgaaggtg cctgatctgt aattaccttt
    16381 tgaggtttac caaattgttt aatgagacgt ttgataaacg catatgctga atgattatct
    16441 cgttgcttac gcaaccaaat atctaatgta tgtccctctg tatcaatggc acgatataaa
    16501 tagctccatt ttccttttat tttgatatac gtctcatcaa tacgccattt gtaataagct
    16561 tttttatgct ttttcttcca aatttgatat aaaattgggg catattcttg aacccaacgg
    16621 tagatcgttg aatgatgaac gtttacacca cgttctctta atatttcaga tatatcacga
    16681 tagctcaatg catatcttag atagtagcca acggctacag tgataacatc cttgttaaat
    16741 tgtttatatc tgaaatagtt catacagaag actccttttt gttaaaatta tattataaat
    16801 tcaactttgc aacagaacct cctaactgta ttaccacctt aaaagtagtt gcagacgcac
    16861 ttcctaaatc gtcagcagtg tttaaccaca tatcatcaac aataatcata tgacctgttg
    16921 atgatactgg agcaaattct gtcaaccctt caactacacc taaaataaat gctttaatct
    16981 gctctataaa acccattttt ctcctccttt taacttatat cagttttttt aaagtatgag
    17041 aataatataa ttacactgaa tatagatgta acaattatga taattaaaga taatagaaat
    17101 ggataagtat taggtaatgt tcctctagat atgtctccaa ctgcagccca aggaaataat
    17161 cctctatgtt cagaattagc agtcattaaa tttatcaaag taattattat ggttaaaaca
    17221 attgtgggaa cataattttt aaaatatatc gacaaaataa ttattggtgg agataatatc
    17281 cataataaca ctccgccaat aacaaatgta aagaatgaat caattattaa actctggctt
    17341 aacccttgaa aatgcaatag catacctagc attaaagtta gcaaccatgc aataacagat
    17401 agtgtttgaa tccacaagaa taataatatt attttactta ctaaaaaact ttctctagat
    17461 ataggtataa ttaataagtt ttttaaagta tcttctatat attctcttcc aaacaaatag
    17521 gctattataa ccccatatag aggaggtcca ataattagca tatgatataa actgacttct
    17581 tcaaataact gtttaaatac aatattagga gtcggtactt tcgtccgcat actaataaaa
    17641 gaagctacaa ccaccataaa aggtgctacg catgtaccta aaatacttat tagaaacata
    17701 tatgatcttt ttaacttaat aaattctgta cggagtagat tatccaattg tgccacctcc
    17761 tactaagtct tcgaaataag tttctagatt atcttctatc actctcatct ggaaaacatc
    17821 aatattgttt aatactaata atctattaat ttcttgttgt ctatcaatat gtgaataaat
    17881 tttaaattcg ccattttctt taattttata gtcataaatt ccgaagttag tttccaacaa
    17941 acatgcaact ttttcttcat ctgatactga tatacttata aattgtctgt tctttttttt
    18001 aaatcttcat acataatttc ttctaacaaa actccgttat gaataatacc caccttgtct
    18061 actaactgct ctatttctga caatatatga cttgaaatta aaatggttat atttctagat
    18121 tgagccagat ccttaatcaa ctttctaatt tcttttatgc caataggatc taatccattc
    18181 gtcggctcat caagtatcaa taattcggga ttgtgcaata aagctctcgc aatccctaaa
    18241 cgttgcttca tacctaaaga ataattttta aacaatttta ctttttcaga agctagtcct
    18301 actatttcta acacttcttc aattgcattt tctttttgta tacctaatat tttagcattt
    18361 atagttaagt tctctttagc tgtcaaatta ctataaaaac ctggcgtttc aaccatagca
    18421 ccaatatttt ttaaaatttc agttttatta ctttcgaact ctttttcaaa tattttaata
    18481 ttacctttcg taggtttaat taagcctaaa agcattctta tagtagttgt tttgcctgca
    18541 ccatttcttc ctaaaaaacc ataaatttgt ccactttcaa cagttatact caaattatta
    18601 actgctatct gacttccata ttgctttgtt aagttattta tttcaattat attattcaaa
    18661 tttttcacct ctggcacctt tcttagtttg ttgttacctt tatcttacgc gcgattagaa
    18721 aaggctgcct ttatctattc ttacaaaaac agccgctaat cttacaaaaa tgaaagattg
    18781 gagttattta aattgaatgg tgaatattga accatcgttt aatgtagatg tagcacttac
    18841 tttatggcct aagcgctttg agattgtgct gacaatatat aaaccaatac cgcttgattt
    18901 ctcacttatt ctaccgttat agcccgagaa acctttatca aagattttcg gtaaatcact
    18961 cgcattaatg ccgataccgt tatctcggat tgataatttc tttgtatttt cgtcaaacgt
    19021 aatccacaca tctttgccac gtgcatattt taatgcattg tttaatattt gctcaatcat
    19081 aattgatgcc catttggcat ctgttaatat aaccgcttca cttttctcat aatgcaactt
    19141 tgtttgatga tgaataaact gtatcgcata acgtttaatc agtggtcgaa ttaattcatc
    19201 tacactcact tccataaaga ccatgtatgt cttttggttc atgagtttca aatagttcag
    19261 tgcaagattc gtgtaattat caatttgtaa gacttcatta cgcacgttag aaatcacgtg
    19321 ttcatcagga tcttcaagca gtaactttga tgctgtaatc ggtgtcttga tttgatgcac
    19381 ccacattaaa aaatatgact ctaactcact ttggtagtta ataaagtcat tacgaagttt
    19441 atggttttcg attcttaaat cttcgttctg ttcctgtagt gtttattctt ttttaaagtt
    19501 catgtaatgg ataccccagt aaatcattga aacaaacaat acaataccta gaccaatcat
    19561 atatgcttgc atcggcacat tatacatgaa taatataaag tagaataaag cacaagtaag
    19621 gatgacaata taaatttcac gttggattga tttcaagaaa ttcatacgtc acctacacga
    19681 tatccgacat ttttcttcgt ttcgataaaa tctgtaagtc ctagtttttg tagctttttg
    19741 cgtaaacgtg taatgttgac agcaagcgta ttgtcatcaa tgaagtgttc tgattcccag
    19801 catttttcga ttaacgcatt acgactgacg aatttgccct tgttctggaa taagctatgc
    19861 atgatttgca attcagtgtg tgtcaggtct atggtttctt cattaaattt aagctttgct
    19921 gcatcaagta gtaactcgca atcatctact gttaaattat taacttgagt ggtgaaatca
    19981 tacgtgcggc gtaatagtgc ttgaatctta gtaattgtaa cagtcatatt aaatggctgg
    20041 ttctgttgca aagtaaaaaa tatagctaat cactaatata tcatgtcagt gttcgtttaa
    20101 cttgctagca tgatgctaat ttcgtggcat ggggaaaatc cgtagatctg aagagaccta
    20161 cggttctttt tatatagagc gtaaatacat tcaatacctt ttaaagtatt ctttgccgta
    20221 ttgatacttt gatatcttgt ctttcttact ttaatatgac ggtgatcttg ctcaatgagg
    20281 ttattcagat atttcgatgt acaatgacag tcaggtttaa gtttaaaagc tttaattatt
    20341 ttagccattg ctgccttcgt tgaaggtgcc tgatctgtaa ctaccttttg aggcttacca
    20401 aattgtttaa tgagacgttt gataaacgca tatgctgaat gattatctcg ttgcttacgc
    20461 aaccaaatat ctaatgtatg tccctctgta tcaatggcac gatataaata gctccatttt
    20521 ccttttattt tgatatacgt ctcatcaata cgccatttgt aataagcttt tttatgcttt
    20581 ttcttccaaa tttgatataa aattggggca tattcttgaa cccaacggta gatcgttgaa
    20641 tgatgaacgt ttacaccacg ttctcttaat atttcagata tatcacgata gctcaatgca
    20701 tatcttagat agtagccaac ggctacagtg ataacatcct tgttaaattg tttatatctg
    20761 aaatagttca tacagaagac tcctttttgt taaaattata ttataaattc aactttgcaa
    20821 cagaaccgta ttttatgagt acactctaaa ttaaggagat gtataatcaa tctaaaattg
    20881 tatttttata cttttgttat ataatctttc tacttagaga tatattgtaa aaaaaccaac
    20941 aaaatgttat attaacatta ctattttatc gatgaaggag gattaaaatg acagcttcta
    21001 tgagactcaa ataaaccttt ttgaatacaa aactaaatta attcaaaaag gcttgtccgc
    21061 aatacacact cataggatga cttatgtcat tttttatcct tcgataggaa taataaacgc
    21121 tttcaaatac taaaacatca taataaattt ttaagtgttt gaaagtgtaa tgtgaatgag
    21181 acgggagtag cctgtctcat ttttttgcgt acacgtcctt taaatataca aggagtgtat
    21241 aaatatggaa caatatacaa ttaaatttaa ccaaatcaat cataaattga cagatttacg
    21301 atcacttaac atcggtcatc tttacgctta ccaatttgaa aaaatagcac ttattggggg
    21361 taatggtact ggcaaaacca cattactaaa tatgattgct caaaaaacaa aaccagaatc
    21421 tggaacagtt gaaacggttg gcgaaattca atattttgaa cagcttaaca tggatgtgga
    21481 aaatgatttt aacacgttag acggtagttt aatgagtgaa ctccatatac ctatgcatac
    21541 aaccgacagt atgagtggtg gtgaaaaagc aaaatataaa ttagctaatg tcatatcaaa
    21601 ttatagtccg atattacttt tagatgaacc tacaaatcac ttggataaaa ttggtaaaga
    21661 ttatctgaaa aatattttaa aatattacta tggtacttta attatagtaa gtcatgatag
    21721 agcacttata gaccaaattg ctgacacaat ttgggatata caagaagatg gcacaataag
    21781 agtgtttaaa ggtaattaca cacagtatca aaatcaatat gaacaagaac agttagaaca
    21841 acaacgtcaa tatgaacagt atataagtga aaaacaaaga ttgtcccaag ccagtaaagc
    21901 taaacgaaat caagcgcaac aaatggcaca agcatcatca aaacaaaaaa acaaaagtat
    21961 agcaccagat cgtttaagtg catcaaaaca aaaaggcacg gttgagaagg ctgctcaaaa
    22021 acaagctaag catattgaaa aaagaatgga acatttggaa gaagttgaaa aaccacaaag
    22081 ttatcatgaa ttcaatttcc cacaaaataa aatttatgat atccataata attatccaat
    22141 cattgcacaa aatctaacat tggttaaagg aagtcaaaaa ctgctaacac aagtacgatt
    22201 ccaaatacca tatggcaaaa atatagcgct cgtaggtgca aatggtgtag gtaagacaac
    22261 tttacttgaa gctatttacc accaaataga gggaattgat tgttctccta aagtgcaaat
    22321 ggcatactat cgtcaacttg cttatgaaga catgcgtgac gtttcattat tgcaatattt
    22381 aatggatgaa acggattcat cagaatcatt cagtagagct attttaaata acttgggttt
    22441 aaatgaagca cttgatcgtt cttgtaatgt tttgagtggt ggggaaagaa cgaaattatc
    22501 gttagcagta ttattttcaa cgaaagcgaa tatgttaatt ttggatgaac caactaattt
    22561 tttagatatt aaaacattag aagcattaga aatgtttatg aataaatatc ctggaatcat
    22621 tttgtttaca tcacatgata caaggtttgt taaacatgta tcagataaaa aatgggaatt
    22681 aacaggacaa tctcttcatg atataactta aaaactatac actaatttat attgaatatt
    22741 aggttcattt atatcaatat aaaaaatacg ttcacaagaa aaatataata gaaataagga
    22801 tccaataaaa tgactcgaca taatgaaatt attaaatgtg cagaaaaata tcaattacac
    22861 atccaacctc aaacaatctc attgaatgaa tcgggacttg attttcaagt tgcatttgga
    22921 aaagataaac atggagtaga atgggttttg agactaccaa gaagacctga cgtttataaa
    22981 cgaacaaaac ccgaaaaaca aacggtagac ttcttacaga agaatgtttc atttgaaata
    23041 ccgaagtgga aagtacatgc aaaagacctt attgcttacc caaaacttac aggtaaaccc
    23101 gcagccacaa tagatccaga aatacaaaat tatgtatggg aaattgaaca caaaccatta
    23161 ccagaaaact ttattaacac attagctgaa acactcgtag atttacacaa cataccagaa
    23221 gaaaacatta acgttcagca tataaatatc aaaaccatac aagaaataaa aaatgacttt
    23281 caaagaagaa tgaataaagt taaagaaact tatggcgtat cagatgaatt atggaacaga
    23341 tggaaacaat ggttagaaaa cgacgaacta tggcctcgac atgcgaccat gatacatggg
    23401 gacttacatc caggacatat aatggtagat aaccaagcaa acgtcacagg tctcatagac
    23461 tggactgaag caacccactc cgacccatca atggacttta taggacacca tcgtgtattc
    23521 gacgacgaag gattagagca acttataaca gcatacggta aagctggagg tgaaatatgg
    23581 ccacgaatga aagagcatat aatagaactc aatgcagtat tcccaatgtt tatcgctgag
    23641 tttgctatgg aatcaggaga atcggcgtat gaaacgatgg cattgaaaga gttaggtatg
    23701 aaagagtaga acttatatta aaagaggccc attttaaaga cgaaggcaat cctgatgaaa
    23761 ttttaaaact gcgtttaatt agtgatggtc tttggttttc tataatgtat taaatatctg
    23821 gacatggaac aaatgcaaca aatggaaaga atcgttttcg aaatttctaa ctccttaaat
    23881 caggaggata aataaacggt cattttcatt gaaagcactt atataaattt catcaatttt
    23941 aatacctacc gtaaatacat ttcataagta ttaaacagat gattaaaatt tttagttaat
    24001 ttaaatattt atgatagaga tgaccttcaa atgaacggtt ctgttacaaa gaaaaaatct
    24061 atatttattt ttagtaagtt ttaattatag atatgtacac tttgagtaca ccctaaccat
    24121 acaaaaagaa ttgttgaaat tataacaatt aaaacgtatg attagggtgt atatttatta
    24181 tggagtgaag atgaatgatt ataggttatg cgagagtatc atcgatagat caaaatttag
    24241 aaagacaatt ggataattta aagacgtttg gtgtggagaa aatctttaca gagaaacagt
    24301 cgggaaagtc agtggaaaat agacctgtat ttcaagaagc actcaatttt gtcagaatgg
    24361 gagatcgatt cgttgtggaa tctattgatc gtttaggacg taactatgat gaaattattg
    24421 aaactgtgaa ttatttaaaa gaaaaagacg ttcagttaat gattaccagc ttacctatga
    24481 tgaatgaagt aattggcaat ccattactgg ataagtttat gaaagattta atcattcaaa
    24541 tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa gcgcaaggga
    24601 ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc tttactttat tcaccaaatg
    24661 ctaaagaccc acagaaacgt gttatttatc atcgcgtggt ggaaatgtta gaagaaggca
    24721 aagcgattag taagattgcg aaagaagtta atatcacaag acaaacagtt tatagaatta
    24781 aacatgataa gggattatct tgataaattg attgtcaatg caaatgagcg tctctcacag
    24841 tgtctcaaat tccataacat attattgaat tgagatttta ataattatac aagaaaaaag
    24901 agtacgagtt cgcagctttc tatatagtaa ttgttttact aataaggtgt tttaaaatat
    24961 attataatgt aaaaagtatt tgacatttgt atcaaaaata tttacactca taaatgtcaa
    25021 atacttttta catttatgag gtgttataat gaatttaatt ccttttatta ttattttaat
    25081 tttttcttgt ttatggacgg ctataactaa caaatattta ccttcagaaa cattagataa
    25141 aaaaggacaa caagatcgat acgatgaaag acaacgtaaa atgtttattg aaatactggc
    25201 taaaagtttt atttggattg tatattgtat gttatttaca ctagtgctta aatttacagg
    25261 tttgtcacca agtattgaag gatcttggtt ttctcaatat ccagaaattt tctttataat
    25321 tgtagcacta tttcttatgc tgtttaatta ctatactaca aataaaaaat atacatctaa
    25381 aggttaaatt aatgaaaaat agaattagag aatatagaaa acaaaaagga atttctcaag
    25441 aaactttaag taaagaatta aaagtgtcta ggcaaactat taatgcaata gaaaacaata
    25501 aatatgatcc tacattgaca ttagcattta agttggcaag attgtttgat acaactgtgg
    25561 atgaattatt ttcttaacca ttcatttatc acaaaaagag agtgcgaatt cgcactctct
    25621 ttttgtgtag tagtactatt aaattttgtc tcaataacga acgtttataa cgcaatcatg
    25681 atgagagtat taatacagtt aattatttga aatactttag tttacataat cgatgattac
    25741 cagaagttct cactatataa aagacactaa aattttataa cttttagtgc ctaatcaatt
    25801 attttagcta ccaaacaaac gactccaaaa ccccttttta ggttccgttt cttcactctt
    25861 ttcttctata tcactatcat tgtcatttag attagctgga acgtcttctt tttttgcttc
    25921 ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt gaatctctgt
    25981 ttctttagtt tcttcctgat ctctgttaat atttacagga ttagtagtat atgttttttc
    26041 ttgtgcatca acgttttgtc tagtgttagt agatgtatca aagggataat taaggtgttt
    26101 ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta atgccagaac
    26161 ttgctgattt tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa attcaattgt
    26221 tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtatcaa tctgattttt
    26281 aaggatttct actatttgag catcgctttt cgattcaaaa ttaatattat ccgacccttt
    26341 tttttgtttg tcttcagtag tactttcaaa accatatttc tttttatttt catttactct
    26401 ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt cctgttttat
    26461 tgtctctata ttcaatcgct taatattatt aaaaatcgtt tgcttactaa cccctaattc
    26521 ttcactcaac tttttcacac ttttcatatc atcaaccctt tataaaatgt ttataaaccc
    26581 ttgataaaat attataagct tataatgctt aataataaag tgattaataa ataaaaataa
    26641 acatccatca acctttttat caagggttta tgaaaggttt atgatattta tcaagggttt
    26701 ataaaccctt gataaagcta tattttccct tttataagtt tatttaaagt gctataataa
    26761 acttaatata acaaaaaccc caactactgg taatagtcgg ggtttggtaa taaaacgttt
    26821 agaaactgtt tatttatata attttcgata cttgtattat ataatgaata atatcttagt
    26881 gcaagcacct aaatcattaa ataaatgtaa agctaaataa aaacgtttta ttacctctta
    26941 ccaaactaaa atatggaaag aggttttttg tc
//
