LOCUS       NC_018886               8513 bp    DNA     circular CON 14-DEC-2023
DEFINITION  Bacillus thuringiensis Bt407 plasmid BTB_9p, complete sequence.
ACCESSION   NC_018886
VERSION     NC_018886.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603279
            Assembly: GCF_000306745.1
KEYWORDS    RefSeq.
SOURCE      Bacillus thuringiensis Bt407
  ORGANISM  Bacillus thuringiensis Bt407
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 8513)
  AUTHORS   Sheppard,A.E., Poehlein,A., Rosenstiel,P., Liesegang,H. and
            Schulenburg,H.
  TITLE     Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-
  JOURNAL   Genome Announc 1 (1) (2013)
   PUBMED   23405326
REFERENCE   2  (bases 1 to 8513)
  AUTHORS   Sheppard,A.E., Poehlein,A., Liesegang,H., Rosenstiel,P. and
            Schulenburg,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2012) Department of Genomic and Applied
            Microbiology, Goettingen Genomics Laboratory,
            Georg-August-University-Goettingen, Grisebachstr. 8, Goettingen,
            Lower Saxony 37079, Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. v2.6
            Sequencing Technology             :: Sanger dideoxy sequencing; 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/14/2023 02:22:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,598
            CDSs (total)                      :: 6,409
            Genes (coding)                    :: 6,240
            CDSs (with protein)               :: 6,240
            Genes (RNA)                       :: 189
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 142
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 95 of 169
            Pseudo Genes (incomplete)         :: 72 of 169
            Pseudo Genes (internal stop)      :: 33 of 169
            Pseudo Genes (multiple problems)  :: 26 of 169
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003898.1.
            Source DNA available from Hinrich Schulenburg, Evolutionary Ecology
            Genetics Zoological Institute, CAU Kiel, Am Botanischen Garten 1-9
            24118 Kiel, Germany.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8513
                     /organism="Bacillus thuringiensis Bt407"
                     /mol_type="genomic DNA"
                     /strain="407"
                     /db_xref="taxon:527021"
                     /plasmid="BTB_9p"
     gene            101..1147
                     /locus_tag="BTB_RS32235"
                     /old_locus_tag="BTB_9p00010"
     CDS             101..1147
                     /locus_tag="BTB_RS32235"
                     /old_locus_tag="BTB_9p00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_001085408.1"
                     /translation="MAKKNQDEITGKLQPKKKQNIKIYEFIKKKMSESGKELFKSCSIF
                     NEFLATKDKKKKKRVKGNDCKNRFCPICAWRKAGKDAVKIATMMEAIKIEEKKEFLFLT
                     LTTPNIKADMVKSEIDRFNKAFKKLFDRRNIQRSIKGYIRKLEMTYDKERFITEEMYNN
                     KKRKAYYDSRGLKVDDHNPNYDTYNPHFHVLLCVDKNYFKRKELYIKQEEWLEMWREVT
                     DMPEITQVHIQKVELIREGNAVAEVAKYSAKDYEMSVSQEVFDVFYLALKGRQLIVYGG
                     LLKDYAKKYEDGELDKYKSTDKNEYYYRLIAMWNKDLMKFEQEYQELSESEKQEYNGHL
                     INEVDVEA"
                     /name="protein rep"
     gene            1151..1348
                     /locus_tag="BTB_RS32240"
                     /old_locus_tag="BTB_9p00020"
     CDS             1151..1348
                     /locus_tag="BTB_RS32240"
                     /old_locus_tag="BTB_9p00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000861196.1"
                     /translation="MKVAGDLYYYCLGCKKFHEYEKIDHKGVNRKLCFYCFKIQSKKTK
                     IIGDAEGRMQICETCHKELF"
                     /name="hypothetical protein"
     gene            complement(2217..2480)
                     /locus_tag="BTB_RS32245"
                     /old_locus_tag="BTB_9p00030"
     CDS             complement(2217..2480)
                     /locus_tag="BTB_RS32245"
                     /old_locus_tag="BTB_9p00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000874967.1"
                     /translation="MAFLTNYKANGKRYFYVEKYVGKKPYTCKQSERIYSIGNERITLE
                     RLTLWILDNSFIPNELIKIGISINDIENWREKVENTIKRYSL"
                     /name="hypothetical protein"
     gene            2754..2981
                     /locus_tag="BTB_RS32250"
                     /old_locus_tag="BTB_9p00040"
     CDS             2754..2981
                     /locus_tag="BTB_RS32250"
                     /old_locus_tag="BTB_9p00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869869.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000869869.1"
                     /translation="MKVVSNIRMIMAKKNIDNISDLVRITGVSRNSINKLWHNENVSSL
                     KLDTLITICEKLDVELLDLIEYIRDDSETK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            3453..4532
                     /locus_tag="BTB_RS32255"
                     /old_locus_tag="BTB_9p00050"
     CDS             3453..4532
                     /locus_tag="BTB_RS32255"
                     /old_locus_tag="BTB_9p00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RapH N-terminal domain-containing protein"
                     /protein_id="WP_001102658.1"
                     /translation="MNVQLGNEQITKLLNDWYQEIRAQHIIKAKQLKQKIEKEINNIEE
                     DQNLLLYYSLIDLRYKILTNDYADREQSLEKIEQLKEHTNNFLDYYYHFFKGMHAMKTG
                     NYSETQKYYDIAEKLLEEIPDEVEKAEFNYAVATFYYHTHQALLATQYANKAKSFFSGK
                     LGYEIKTGACENTLGMACITLREFSVAEEYLLSAINKFEKHSENKLALIVRYNLGLLYA
                     DQNLSELAIRYLLESFENQEDDYKTMFLLAQEYYKLKQTNTVNTYIEKGLNVCNQEYKI
                     HFLFLQALNNKLSTEQLEKVMLDAIPYFEKQNLWKYIQDYTEELAIRFYEEKNKDKSNE
                     YFYKSYKAKRNLLERESLK"
                     /name="RapH N-terminal domain-containing protein"
     gene            4529..4675
                     /locus_tag="BTB_RS35225"
                     /old_locus_tag="BTB_9p00060"
     CDS             4529..4675
                     /locus_tag="BTB_RS35225"
                     /old_locus_tag="BTB_9p00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000976019.1"
                     /translation="MMKKFSLILIGVACTTGIFFSQFNNSIQTHDAKEKNDIIQQYAHG
                     KDI"
                     /name="hypothetical protein"
     gene            4795..5376
                     /locus_tag="BTB_RS32260"
                     /old_locus_tag="BTB_9p00070"
     CDS             4795..5376
                     /locus_tag="BTB_RS32260"
                     /old_locus_tag="BTB_9p00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000723966.1"
                     /translation="MKKISIERSNWRKTYKKMIPVLLVGGILAGNVAFVTNNVFAATTN
                     NNNIIQTKQSLVSGQDEKSINELAEAFQFMHEEAAIYNNQGEIVDFDFNKIEAKYGNDV
                     GLDALKQQIKKDKSDIAGLSFTSCMKDALYDFFGVNAVQAAFNGGLAYYLEKKLWKEAA
                     KIGVKFFIGSSVAGLAATLAYYGGKCAIYG"
                     /name="hypothetical protein"
     gene            5369..5566
                     /locus_tag="BTB_RS32265"
                     /old_locus_tag="BTB_9p00080"
     CDS             5369..5566
                     /locus_tag="BTB_RS32265"
                     /old_locus_tag="BTB_9p00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000361625.1"
                     /translation="MDKSSILKQMYFILFPVTLFLSLNIYQWIVKSDYSFTGYIIQNLI
                     IVALALVAAIIAYLITKKNI"
                     /name="hypothetical protein"
     gene            6418..6588
                     /locus_tag="BTB_RS35230"
                     /old_locus_tag="BTB_9p00090"
     CDS             6418..6588
                     /locus_tag="BTB_RS35230"
                     /old_locus_tag="BTB_9p00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218510.1"
                     /translation="MALSLLGLIVFKKSWLVAEKNREDWRGCIAWQRDMLCSRGEYKKR
                     LFNTWMSTVKS"
                     /name="hypothetical protein"
     gene            6939..8144
                     /gene="mobV"
                     /locus_tag="BTB_RS32275"
                     /old_locus_tag="BTB_9p00100"
     CDS             6939..8144
                     /gene="mobV"
                     /locus_tag="BTB_RS32275"
                     /old_locus_tag="BTB_9p00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033080.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_000033305.1"
                     /translation="MSKFVICHMQKFKMRDVKGLQIHNQREKESHSNSDIIQARTEQNY
                     DLIHDKEKVDYKKLIQNRIDNGVVSNRAIRKDAVVCCSFMISASPDYMNSLSQVEQRRF
                     FEESLRFLKGRYGEENFVYASVHVDEKTPHMHVGMVPVNEKQKLSAYSFFKNKSEFHDL
                     QDKIYEHVKEKGFDIERGVSSDRKHLSTQRFKAVTLQQEIEELEQEKKGIDSRLHDLKM
                     SLDQAKSVDEIPVKEKGGFIRSKTVEITSEDFESIKVLARSSEALREDVRRLKNESGVI
                     TREKDGLYREKCILEGQITELKRENRGLKEENDFFKKTLERVKELYKEKLPELAGVIGY
                     VKGSILDRMNCKFLKRYFTSDDEVRGAQKFLNHKQEHEEQQKRLKQVRSSQQKNRDQGL
                     ER"
                     /name="mobV"
     Typing          77..1129
                     /name="rep_cluster_617"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.934"
                     /coverage="95.0"
                     /evalue="0.0"
     Typing          6940..8141
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 caagtccaaa aaaaggattc gtacaccctt ttttatatcg aatatgaaat tcagaaatta
       61 gaaattctga tgtttttcag ataggactaa tatatcaaat atggcaaaga aaaatcaaga
      121 tgaaatcact ggtaaattac aacctaaaaa gaaacagaat atcaagattt acgaatttat
      181 aaagaagaaa atgagtgaga gcgggaaaga attgtttaaa tcgtgcagta tctttaatga
      241 atttttggct acaaaggata aaaagaagaa gaaacgagta aaggggaatg attgtaaaaa
      301 tcgattttgt ccgatttgtg cttggaggaa agcagggaag gacgcggtga aaatcgcaac
      361 gatgatggaa gcaattaaga ttgaggaaaa gaaagagttt ctttttttaa cgttgacgac
      421 tccaaatatt aaagctgata tggtgaaaag tgagattgat agatttaata aagcttttaa
      481 aaagttattt gatagacgta atattcaacg ttctattaag ggttatatta gaaagctaga
      541 aatgacgtat gataaagaac gattcatcac tgaagaaatg tataacaaca aaaagagaaa
      601 agcatattat gattctcgtg gattgaaagt agacgatcat aacccgaatt atgatacata
      661 taatcctcat tttcatgtat tgctttgtgt tgataaaaat tattttaaac gtaaagagct
      721 ttatattaag caagaagaat ggttagaaat gtggcgagaa gtaacagata tgccagagat
      781 tacgcaagta catattcaaa aagtagagtt aatacgagaa ggaaatgcag ttgcggaggt
      841 tgcgaagtat tcagcgaaag actatgaaat gtcggttagt caagaagtgt ttgacgtgtt
      901 ctatttagca ttaaaaggtc gtcaattaat tgtttacggt ggattattaa aagattatgc
      961 gaaaaaatat gaagatggcg aattggacaa gtataagagt acagacaaga atgaatatta
     1021 ttatagatta atcgcaatgt ggaataagga tttaatgaaa tttgaacaag agtatcaaga
     1081 gttatctgag agtgagaagc aagagtataa cggtcattta attaatgaag tagatgtgga
     1141 ggcgtagtgt atgaaagtag cgggagattt atattattat tgtcttggtt gtaaaaagtt
     1201 tcatgaatat gaaaaaattg atcataaagg tgtaaataga aaattatgtt tttattgttt
     1261 caagattcaa tctaaaaaaa cgaaaattat tggtgatgct gaaggtagaa tgcaaatttg
     1321 tgagacttgt cataaagaat tgttttagtt ggttgatttg tgaaaaaagc aaagtcaaat
     1381 gttagaaatt tttaataagg gaactgactg ttatatcaag tcagttccct tattttattg
     1441 agtctatttt tgagtgcagc aagtagcatt caaaagtttt tttatgattt aacaaaaagg
     1501 agtttttctt aaatttaaat ttcgtgaatt tgtaaattta tttttaaagt ttatttcgag
     1561 atatattttg ttctactaat tttgttttac taacgtacga ggtgaaaact taaagtgtgc
     1621 gcatgaattt ttttagtaat atatattacg ataaaatacc gcacgttttt tgatgatttt
     1681 tttgaaaata tagttttgag aaattctaaa ttttcggggc tgattttgga ttttttatgt
     1741 gggatttgat tttggaattt gttaaattgg aaatctcgat ttttcgattt tcggaatttt
     1801 tgttttctct tttctttgtt attctgtatt tcgaaattaa ggagtttata taataccttc
     1861 atgacgaact gaaaacgaaa aaactttgct cgcatattta attcatagat atttcatatc
     1921 gttaaaaagt tgcaccgttt caaacgagtt gtgtgataaa aagatgttta gattatgttt
     1981 gaaattgttg tttctgtgaa ttttttattt cgcgatttct gtatattttt aatccttttt
     2041 actcttaaaa tctttttgct tttgtgcgca aatgaaaaaa tcaaaaagtc acgcgtaact
     2101 tttattaaat atataaatat attattaaaa tacctaaccc ttttatgatg aaaaaatata
     2161 aatagttaaa gaaaaaagac tgataaaaaa tatcagtctt ttttctttag ttttatttat
     2221 aaagagtatc tctttatggt gttttctact ttttctctcc agttctctat atcgttaatt
     2281 gatattccga tctttattaa ttcgtttgga atgaaactgt tatctaaaat ccataaagtg
     2341 agcctttcta atgtgattct ttcgtttcca attgaataaa tacgttcact ttgtttgcaa
     2401 gtatatggtt ttttaccaac atatttttct acataaaagt atctttttcc gtttgctttg
     2461 taatttgtta ggaatgccaa aatgataatc tcctcttagt ttttttagag ttaaaaatac
     2521 attttaaaag attaaatttt aagttatata tttaatttta actctaaggg gttaaaattt
     2581 caattaaaac aaataaaatt aaataataaa acaatatatt ttatttttaa ggttaatatt
     2641 aaatgtgaat atataaaaaa taaccttaat attatttaat ttatgtttta tttgtataaa
     2701 agtatccttg taagtaaaat ggtatgtaca ttgaatgaaa aggagtatga aaaatgaagg
     2761 tagtaagtaa tattcgtatg attatggcga aaaagaatat agataatatt tcggatttgg
     2821 tgagaataac gggagtaagt cgtaattcta ttaataagtt gtggcacaat gagaatgtgt
     2881 cttctttaaa attagataca ttgataacga tctgtgagaa gttggatgtt gagttattgg
     2941 atttaattga atatattcga gatgatagtg agacaaaata atttaggggc tattttagct
     3001 ttagatagct tgtgtatgat gaaagcatat ttttgctaat cgacaatgag ttatattcac
     3061 atatgttttt tttgtagggc tatatgtgta tttaaagttt tgatttctat ttgttattgt
     3121 atgaatatgg tttgaatgtg gtaaatgaaa ttatagtctt gctaggtgcg tcaacacctt
     3181 ggaagatgag cggtactggc atacttcgtg atttcattga tagtagtgca gtaaagtgat
     3241 ggaattgatg agtattgaaa aagagttcct gtttgggggc tcttttttta tttgttacta
     3301 agtattttta aatagtgaag gtgctacact atttaaaaat acagaatatt aaaaacttta
     3361 tatatcaact gttgaaaagt tagtcttata caatagcatg ataacatgat agaaaataaa
     3421 atatagataa ttttggaaaa ggagaagatt ctatgaatgt tcaactagga aacgaacaaa
     3481 ttacaaaatt attaaatgat tggtatcaag aaattcgagc gcaacacatt attaaagcaa
     3541 aacaattaaa acaaaagatt gaaaaagaaa ttaacaacat agaagaagac caaaatttac
     3601 ttttatatta ttcacttatt gatttgagat acaagattct tacaaacgac tatgcagata
     3661 gagaacaatc tttagaaaaa atcgaacaat taaaagaaca cacaaataat tttttagatt
     3721 actattatca tttctttaaa ggcatgcatg caatgaaaac aggaaattat agtgaaactc
     3781 aaaaatatta tgatatagca gaaaaattac tagaagaaat tcctgatgaa gtagaaaaag
     3841 ctgaatttaa ttatgctgtt gcaactttct attatcatac tcatcaagcc ttattagcaa
     3901 ctcaatatgc taacaaagcc aaaagttttt ttagtgggaa actaggatac gagattaaaa
     3961 ccggagcatg tgaaaacaca cttggtatgg cttgtattac attaagggaa ttttctgttg
     4021 cagaagaata cttgctttcc gcaattaata aatttgaaaa acacagtgaa aacaaattag
     4081 ctttaatcgt acgttataac ttaggtcttt tatatgcaga tcaaaatctt tctgaacttg
     4141 caatccgtta tcttcttgaa tcctttgaaa atcaagaaga cgattacaaa acaatgtttt
     4201 tattagcaca agaatattac aagttaaaac aaacaaatac agtaaacaca tatattgaaa
     4261 aagggctaaa tgtttgtaac caagaatata aaattcattt cttattttta caagcattaa
     4321 acaataaatt atctactgaa caattagaaa aagtcatgtt agacgcgatt ccatattttg
     4381 aaaaacaaaa tctatggaaa tacatacaag attatactga agaattggct ataagatttt
     4441 atgaagaaaa gaataaggat aaatctaatg aatattttta taaaagttac aaagctaaaa
     4501 gaaacttatt agaaagggag tcattgaaat gatgaaaaaa tttagtctga tactaatagg
     4561 ggtagcatgt acaacaggta ttttcttttc ccaattcaat aattccattc aaacacatga
     4621 tgctaaagaa aaaaatgata ttattcaaca atatgcacat ggaaaagata tttaaaagca
     4681 aattccaaca attagcaatc gacctaaata ttaggattat taacaaaata ttgaattata
     4741 tgtaaattaa gtttattatc tattttgaat aataaactta aggggatgaa atttatgaaa
     4801 aaaattagta ttgagagaag taattggaga aaaacatata aaaaaatgat tccagtattg
     4861 ttagtcggag gaatattggc aggaaatgta gcatttgtga caaataatgt ttttgcggca
     4921 actacaaata acaacaatat aatacaaacg aaacagtctc tcgtttctgg tcaagatgaa
     4981 aagagcatta atgaattagc agaagcgttt caatttatgc atgaagaagc cgctatatat
     5041 aataatcaag gtgaaattgt tgattttgat tttaataaaa tagaagcgaa atatgggaat
     5101 gatgttggtt tagatgcact taaacaacaa attaaaaaag ataaaagtga tattgctggt
     5161 ttatctttta caagttgcat gaaagatgct ttatatgact tttttggagt aaatgctgta
     5221 caagccgcat ttaatggtgg attggcatat tatcttgaga aaaaattatg gaaagaagcg
     5281 gctaaaatag gcgttaaatt ctttatagga agtagcgtag caggtttagc ggctacttta
     5341 gcttattatg gaggtaagtg tgcaatttat ggataaaagt tcaattttaa aacaaatgta
     5401 ttttatttta tttccggtaa cactttttct atctctaaat atttatcaat ggattgttaa
     5461 aagtgattac tcatttacag gatatataat ccaaaattta attattgtag cattagcgtt
     5521 agtagcagct atcatagctt atttaattac taaaaaaaat atttaacaca taatgttagt
     5581 ctaaataaca gaaaattcta acccttattc ttattttgta ttatactggt tatgtacagg
     5641 taaaatggtt tacaagttaa tttttcctcg tttcaaaaaa agtccattct tttcaaaaga
     5701 atggactttt ttcttgttat atttgctgta actattaaaa gggcatcaaa acgatctaca
     5761 aaagcctcaa gacgacccac aaaccatctt taaacggtct caaaacgaac tacaacccga
     5821 aaaaacgcat cccagttttt ttaggtttaa ttttaagcgc ataccaagcg catataggcg
     5881 catacgggac acatacaaag tgccgaaaaa cgcatatagg tcgcatacaa acggtagaaa
     5941 tacatcccta aaaatagagt gatagaaacc caataggcac agcctatttc accacttttt
     6001 ttgcaaagtg ggattcggtt tccttatgct ctttttttat ttttgctttt taagggtctt
     6061 ataatcgttt ttaagtattt taggatgttg ggtttcttaa gggaactaga agttcctaga
     6121 atggattctg agcgttctga ggtgtatttt tctatggatt cgatattgga attgctctag
     6181 gaatagttgt cgttttattc tgtggctgtt ccgacagtgg ttctcataaa gaatatgatt
     6241 gtatcaatag atttgatgat gtttgaaaaa tagagaatag ttgaagctct tcctgtaaaa
     6301 caaaaaaaat tatgtttgta gaggaagtag tcatttcact acaagaaaat tcccatagat
     6361 cggtggcgag ttgaaaaatg ttgaaggttg gcgaggacat tttacgagga cgcgggaatg
     6421 gctttgtcat tgttggggtt aatagttttt aagaaaagtt ggttagtagc tgaaaaaaat
     6481 agggaagatt ggcgaggatg tattgcatgg cagcgggaca tgttatgtag tcgtggtgaa
     6541 tataaaaaga gactttttaa tacatggatg tcaactgtaa aaagttagag gtagttgtat
     6601 gatgtttgtc caacggtaag cggaacgaag tgagcattaa ggagtggacg aacccactgt
     6661 gcccagaacc ctcttggaac tccaaaacgt tagccgtttt ggggatgcca accggcgagg
     6721 gagtccctca aggattgagg ggttggggag ttcgattgaa aggggtcaag gggaagagtt
     6781 tcccttgtgg gtttgggcaa agcccatgat tttttttgcc atgcttgtta tggctcggcg
     6841 gtagccgaaa tgtcccgaag ggcacacgtg tttacgcagt aaactgtagt gtgctactgt
     6901 ttacatggaa ctacccccga aaaaaaggag cgaggcccat gtcgaagttc gtgatttgcc
     6961 atatgcaaaa atttaagatg agagatgtga aaggattaca aatacataat caacgtgaaa
     7021 aagaaagtca ttccaattca gatattattc aagcacgaac ggaacagaat tatgatctga
     7081 ttcatgacaa agaaaaagtg gattataaga aattaattca aaatcgaatt gataatggtg
     7141 ttgtatctaa tcgtgcaatt cggaaagacg ctgttgtttg ttgttcgttc atgatttcgg
     7201 ctagtccgga ttatatgaat tctttatctc aagtggaaca gagacgattc tttgaagagt
     7261 ctcttcgttt tttgaagggg agatatggag aagagaactt tgtgtatgct tccgtacatg
     7321 ttgatgaaaa aacacctcat atgcatgtgg gtatggttcc agttaatgaa aaacaaaaac
     7381 tatcagcgta ttcatttttt aaaaacaaat cagagtttca tgatttacaa gataaaatct
     7441 atgaacatgt gaaagaaaag ggatttgata tagagcgtgg tgtttctagt gatagaaaac
     7501 atttatcgac gcagcggttt aaagcggtga ctttacaaca agaaatagaa gaactagagc
     7561 aagaaaagaa gggaatagat agtcgtcttc atgatttaaa aatgtcttta gatcaagcaa
     7621 aaagtgtgga tgagatccca gttaaagaaa aaggtgggtt tatacgctct aaaacggtcg
     7681 agattacctc ggaagacttc gaaagtataa aagtattagc taggtcgtcg gaagccctta
     7741 gagaagatgt tagacgcctt aaaaacgaat caggtgtaat tacacgtgaa aaagatgggc
     7801 tgtatagaga gaaatgtatt ttagaggggc aaataacaga attgaaaaga gagaatcgag
     7861 gattgaagga agagaatgat ttctttaaga aaacgttgga acgagtgaaa gagttgtata
     7921 aagaaaagct tcctgaattg gctggggtga ttggttacgt taaggggagt atattggaca
     7981 ggatgaattg caaattttta aaacgatatt ttactagtga tgatgaagtg agaggcgctc
     8041 aaaagttttt gaatcataaa caagagcatg aagaacaaca aaagagatta aaacaagtgc
     8101 gaagtagcca acagaaaaat cgggaccagg gattggagag atagtgtggt tctgtttgag
     8161 ttttttgttt tttagattta tagcgttagc ggaatttgtt ttttataact tgcttaagat
     8221 gagtatgttt ctcagatgtt ttatccgtta aaaaaaatgg ttttgaacga aaaaaaatgc
     8281 ccctgtccac ggagtggatt taggggcatt tttttatgat ttttcgtgtt cgaaaaatcg
     8341 agttttttct ttctttaata cataggtaac tatttcggca acgaaattga tgcctatgta
     8401 ttcttttagc ccttatgtat caagggtttg taaaaaaaaa gacttgcttt ttcaggcgga
     8461 tagatttatc atttttagtg tcgaattaaa aatcataaat accacgagag gag
//
