LOCUS       NC_016979               5247 bp    DNA     circular CON 28-NOV-2023
DEFINITION  Klebsiella pneumoniae plasmid pUUH239.1, complete sequence.
ACCESSION   NC_016979
VERSION     NC_016979.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224418
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5247)
  AUTHORS   Sandegren,L., Linkevicius,M., Lytsy,B., Melhus,A. and Andersson,D.I.
  TITLE     Transfer of an Escherichia coli ST131 multiresistance cassette has
            created a Klebsiella pneumoniae-specific plasmid associated with a
            major nosocomial outbreak
  JOURNAL   J Antimicrob Chemother 67 (1), 74-83 (2012)
   PUBMED   21990049
REFERENCE   2  (bases 1 to 5247)
  AUTHORS   Sandegren,L., Linkevicius,M., Lytsy,B., Melhus,A. and Andersson,D.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2011) Department of Medical Biochemistry and
            Microbiology, Uppsala University, Husargatan 3, BMC Box 582, Uppsala
            SE-75123, Sweden
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/28/2023 03:32:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7
            CDSs (total)                      :: 7
            Genes (coding)                    :: 6
            CDSs (with protein)               :: 6
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 1
            CDSs (without protein)            :: 1
            Pseudo Genes (ambiguous residues) :: 0 of 1
            Pseudo Genes (frameshifted)       :: 0 of 1
            Pseudo Genes (incomplete)         :: 1 of 1
            Pseudo Genes (internal stop)      :: 0 of 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002473.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5247
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="U-0608239"
                     /db_xref="taxon:573"
                     /plasmid="pUUH239.1"
     gene            238..399
                     /locus_tag="HS314_RS00040"
     CDS             238..399
                     /locus_tag="HS314_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023144844.1"
                     /translation="MHEPPVQSDRCAFSGNYHLESNPERHGSSPLAAAIGNGLEEVSLE
                     VLRQLRLN"
                     /name="hypothetical protein"
     gene            complement(552..1172)
                     /locus_tag="HS314_RS00005"
                     /old_locus_tag="PUUH_pUUH2391p0001"
     CDS             complement(552..1172)
                     /locus_tag="HS314_RS00005"
                     /old_locus_tag="PUUH_pUUH2391p0001"
                     /inference="COORDINATES: protein motif:HMM:NF025084.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RloB family protein"
                     /protein_id="WP_023312615.1"
                     /translation="MSKKHGNNKKVPQVMYIYCEGEKTEPLYLEAYISDRSKRTLSVFK
                     IPKTRKNTPEQLVDEAIKKKNSSSSAEGDVFWVVYDQEHLTPSSISCHQKAWNKANRHG
                     INIAISCVCFELWLLLHFGFTTKDFSSYDNLMSSSPLKKLITNYDKGSKLTYLAIRERI
                     GTAKDNARKLDIYAKTNYKNTHEPYLFPCYTSFHELLKAIDDF"
                     /name="RloB family protein"
     gene            complement(1165..2520)
                     /locus_tag="HS314_RS00010"
                     /old_locus_tag="PUUH_pUUH2391p0002"
     CDS             complement(1165..2520)
                     /locus_tag="HS314_RS00010"
                     /old_locus_tag="PUUH_pUUH2391p0002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498067.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_014386473.1"
                     /translation="MFVYLTIENFRSVKEKSTLNLSASGSSNHLTTHIYKNDGMNVGTL
                     MSAGIYGANASGKSNVLMAFEAIKFIATESGDLKEGKRIPCYEPYALSSATNEAPVKFE
                     AEFYSVEGNRFSYEVAFIKNRILFESLDYYPSRVKANLFTRDESDTWETIKFGGHYKGG
                     IKKIPFFPNNSYLAKAGNNAASPDIIKEAYNFFRKGIRHIGLNEKIRISSFGEREDVVN
                     ETAKVLCMVDTGVSGISVREVEAEIPIKMDEEIPQEIKEIIEEDYKYRYMFSHPTDEGG
                     SVSFPMGRESEGTQKLFEIIPLIRSAFNDSMVVIVDELDNSLHPHIADLIVKLFNDPDV
                     NKKGSQLVFSTHNMQLMAPEKMRRDQIWFCEKNKGASSLYSLDDFDKKKIKTTTPYAAW
                     YDEGRFGGVPDINYLKVASFISGDISLVMPDIDVKELSDGFFEEFDGDLSDE"
                     /name="ATP-binding protein"
     gene            complement(3153..3365)
                     /locus_tag="HS314_RS00015"
                     /old_locus_tag="PUUH_pUUH2391p0004"
     CDS             complement(3153..3365)
                     /locus_tag="HS314_RS00015"
                     /old_locus_tag="PUUH_pUUH2391p0004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137423.1"
                     /translation="MTELEKQLLTALEQLHQDYSQRLDEWESAFAEWQKMSGLMQRENA
                     ALNERVTRLSQQVANLSRQLQRLSQ"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(3369..3854)
                     /locus_tag="HS314_RS00020"
                     /old_locus_tag="PUUH_pUUH2391p0005"
     CDS             complement(3369..3854)
                     /locus_tag="HS314_RS00020"
                     /old_locus_tag="PUUH_pUUH2391p0005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_013631087.1"
                     /translation="MSSLLALAKDLEQQSKAQQQSTGEMLKAAFSEHEQSVKAELSASA
                     KRISDAISAHEQGMTAAMQSNRLSVLRMVGRTWLTITLVSVLLIATSGSILWWQGQQIT
                     GNYQTIRAQERTQAMLSEKNHGVQLSLCGEKKLSCVKVNPKAGAYGEEGNWMVLERK"
                     /name="MbeB family mobilization protein"
     gene            complement(<3892..4566)
                     /locus_tag="HS314_RS00045"
                     /pseudo=""
     CDS             complement(<3892..4566)
                     /locus_tag="HS314_RS00045"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(4529..4849)
                     /locus_tag="HS314_RS00030"
                     /old_locus_tag="PUUH_pUUH2391p0006"
     CDS             complement(4529..4849)
                     /locus_tag="HS314_RS00030"
                     /old_locus_tag="PUUH_pUUH2391p0006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_014386475.1"
                     /translation="MLTMWVTEDEHRRLLERCDGKQLAAWMRQTCLDEKPARAGRLPSI
                     SPALLRQLAGMGNNLNQIARKVNAGGAGHDRVQIVAALMAIDAGLERLRHAVLEKGGDD
                     DR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     Typing          complement(4964..5136)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="84.659"
                     /coverage="100.0"
                     /evalue="9.74e-41"
     Typing          3..346
                     /name="rep_cluster_2373"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.509"
                     /coverage="80.0"
                     /evalue="1.08e-148"
     Typing          5083..5247
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="91.018"
                     /coverage="99.0"
                     /evalue="8.95e-56"
     Typing          complement(3038..4539)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tttttccata ggctccgccc cctgacaagc atcacgaaat ctgacgctca aatcagtggt
       61 ggcgaaaccc gacaggacta taaagatacc aggcgtttcc ccctggtggc tccctcgtgc
      121 gctctcctgt tcctgccttt cggtttaccg gtgtcattcc gctgttatgg ccgcgtttgt
      181 ctcattccac gcctgacact cagttccggg taggcagttc gctccaagct ggactgtatg
      241 cacgaacccc ccgttcagtc cgaccgctgc gccttctccg gtaactatca tcttgagtcc
      301 aacccggaaa gacacggttc atcgccactg gcagcagcca ttggtaacgg attagaggaa
      361 gtgagtcttg aagttctgcg ccagttaagg ctaaactgaa aggacaattt ttggtgactg
      421 cgctccctct aagccagtta cccggtacat aagttggtag ctcatgtacc ttccaaaaac
      481 caccgttggt agcggtggtt tttatttttc atagattaca gcctgtaata agccatggtc
      541 aatggattac ttcaaaagtc gtcaatcgcc ttaagtagct catggaatga tgtataacat
      601 ggaaatagat aaggttcgtg cgtgttttta taattagttt tagcgtaaat atctagcttt
      661 cttgcgttat ctttcgcagt accaatcctc tctcttatag caaggtaagt tagtttacta
      721 cctttatcat agttagttat taattttttt agcggggagc tagacatcaa attatcatac
      781 gacgaaaaat ctttggttgt gaagccgaaa tgcaacaata accataattc aaaacaaaca
      841 caggatattg ctatatttat cccatgccta ttagctttat tccatgcctt ttgatgacat
      901 gaaatagacg aaggcgtcag atgctcttga tcataaacaa cccaaaagac gtcaccttct
      961 gcggaagatg atgaattctt tttctttatc gcctcatcca ccaactgctc aggtgtattt
     1021 ttccttgttt taggtatttt aaatacactt aaagttcttt tagatctgtc tgaaatataa
     1081 gcctcaaggt ataatggttc ggttttctca ccctcacagt atatatacat tacttgtggg
     1141 actttcttat tatttccatg ttttttactc atcagaaaga tccccgtcaa actcttcaaa
     1201 aaaaccatca gacaattctt tgacgtcaat atccggcatt accaaggata tatcaccaga
     1261 tataaatgag gctaccttta agtagtttat gtcgggaacc ccaccaaacc taccctcatc
     1321 ataccaagct gcgtaaggtg ttgttgtttt tatctttttc ttatcaaaat catctaagct
     1381 ataaagagac gacgcacctt tatttttttc acaaaaccat atctgatctc ttctcatttt
     1441 ctctggagcc attaactgca tattatgggt tgagaataca agttgtgagc cttttttatt
     1501 gacatcagga tcattaaata acttaacaat caagtcagca atatgcgggt gcaagctatt
     1561 atctaactca tcaacaatta caaccatact atcattaaac gcagatctaa ttagaggtat
     1621 gatttcaaat aatttttggg tgccttcaga ctctctcccc atagggaaag aaacactccc
     1681 cccttcatca gtaggatgag agaacatata acgatattta taatcttctt caattatctc
     1741 ctttatttct tgagggattt cctcatccat ttttattggt atttccgcct caacctcccg
     1801 tacagatata ccggaaacac cagtgtcaac catgcataaa accttggccg tttcatttac
     1861 gacgtcctcc ctctccccaa aagaagatat tcttatcttt tcatttaaac ctatatgtct
     1921 aattcccttt ctaaaaaagt tataagcttc tttaattatg tctggtgatg cggcattatt
     1981 acctgctttc gctaagtatg aattattagg gaagaatggt atttttttaa tacctccttt
     2041 ataatgccca ccaaacttga ttgtttccca ggtgtcgctc tcatctctag taaataaatt
     2101 tgctttaacc ctagatggat aatagtctaa tgattcaaat aaaatccgat ttttaataaa
     2161 agcaacttca taactgaacc gattcccctc aacagaataa aattcagcct caaactttac
     2221 aggagcctca ttcgtagccg aagaaagagc atatggctca tagcagggaa tccgtttacc
     2281 ttctttcaaa tcaccgcttt ctgttgcgat aaattttata gcttcaaaag ccatgagaac
     2341 gttagattta ccagacgcat tagcaccata aatcccagca ctcatgagcg ttccaacatt
     2401 cattccatca tttttataga tatgagttgt taaatggtta ctagaaccgg atgcgctcaa
     2461 gtttaatgtc gatttttcct taaccgacct aaaattttca atagtcaaat aaacaaacat
     2521 gcatacctcc taacggggat ttttcgccaa aaaagcgaaa aatcaatcat aggacagata
     2581 tcctatatgt tttaattttg gaacaacatc ttccttaaaa aacgttgtgc tatttataat
     2641 tacacgctat ttaccataac atctgttgcc cgcaccgctc cggacaggtt cgccacaaac
     2701 ggggcggcag tcaggtaaaa ccggcaacaa accacccgat acaccgcccc gttcgtgaca
     2761 gataaatttt acccggctgc atggtcatgc agccagatgc atacggtctg atttcaggcc
     2821 agaatccgga tgaacgcctt aaaaacagga aaatgcttct ccagccagtc ccagatctcc
     2881 agcgccatgt acaggcaatt cagcaccgtc tcaatcacgt taaacagtct cataatccct
     2941 ccgttgtata cgctgtgatg gaaacatcac gaccgtattt agcgggaaat ttatgagccc
     3001 ttcttcttgg ggtttgtcac tggatgcgcg cagtcagccc agcgtcggac cgtcatagct
     3061 ccgctgccgg gaacgggttt ccgccagctc tttttcatgc tgtttctgct cgtatgcccg
     3121 ttcggcggcc accgccattt catgccgctg cactactggc tcaaacgctg taactgcctg
     3181 ctcaagttcg ccacctgctg actcaagcgc gtgacgcgct cgttcagcgc cgcgttctcc
     3241 cgttgcataa gaccagacat cttctgccat tccgcgaagg cgctctccca ctcgtccagc
     3301 ctttgcgagt agtcctgatg tagctgctct aatgcggtca gcaactgttt ttccagttcc
     3361 gtcatgggct atttcctctc cagtaccatc cagttccctt cctccccgta agctcccgct
     3421 ttcgggttca ctttgacgca ggacagtttc ttctccccgc agagcgacag ctgcacgccg
     3481 tggttcttct ccgacagcat ggcctgcgtc cgctcctgcg cccggatagt ctggtaattc
     3541 ccggtgatct gctgcccctg ccaccacaga atgctcccgc tcgtggcgat cagcagtacc
     3601 gagaccaggg tgatggtcag ccacgtccgg ccgaccatac gcagcacgct cagccggttc
     3661 gactgcatcg ccgcggtcat accctgctcg tgggcgctga tggcgtcgct gattctcttc
     3721 gcgcttgcgc tcagttccgc ttttacagac tgctcgtgct cgctgaatgc ggctttcagc
     3781 atctcgccgg tactctgctg ctgcgctttc gattgctgct ccaagtcctt cgccagcgct
     3841 aaaagactgc tcataaatgg ctcccttcag tcggatgttt cgccccccgt ccgggtcggc
     3901 aatgctgata ctgttttttg tggtgcggac cacctcaaaa cctgccgctg tgagcgcccc
     3961 tgtgacgtcc tcgcgcgttt tgagctcccc ggatgaggct aaggccagca acccacgtgt
     4021 aatcgcctga gcggcttcca gcttcgtttc cggcagtgcg gacggcgtga ccagtaaccg
     4081 tcggttctcc ggggcgtttg gatcatgcag ccccagcctg ccgttcacca cggtctgcca
     4141 ggcatcgatg cgcggccggt cggcgcgatc gtagtacggc tgcaggcgtt tcccggtcag
     4201 cagttcagtg ttggggatca ggaaattcag ctccagccgc cccttgtcgg tgtgctccac
     4261 ccacagaatg ctgtactggt ctttatcgag cccgggcatc agaacccgct caaagctggc
     4321 catgatctgc tcccgctgcc cgggcggcag ttcagcctcc gcgaacgaca gcacgccgga
     4381 ggtgtacttt ttcgcatacg gcgaggcatc gatagctccc ggacttcctc cggttttccc
     4441 tgcagcacgg tcgccccctc gcgctgccgt cttttcccag cagtaatcca ccggaccggc
     4501 accaccaccg cgcccccggg ggtgaaattt aacgatcatc atccccccct ttttccagca
     4561 ccgcatgccg cagccgctcc agtcccgcgt cgattgccat cagtgcggcc acaatctgca
     4621 cccggtcatg accggcacca ccggcattca ctttccgggc gatctggttc aggttgttcc
     4681 ccataccggc aagctggcgc agcagcgccg gcgatatcga cggcagtctg ccggcacgcg
     4741 ccggcttctc atcgaggcag gtctgacgca tccacgccgc cagctgcttg ccgtcgcacc
     4801 gctcgagcag ccgccggtgt tcgtcttccg tcacccacat cgtgagcatc ttgttgcgtt
     4861 tgtctgccag agtagcctcc tgataacacc gggacgggcg ggaaatgttt cccggtcggc
     4921 acggtgttgg acaagccgca ggcgcgtcag tcgcttttag cgggtttcgg ggcgcagccc
     4981 tgaaccagtc acgtagcgct agcggagtgt atactggctt attatgttgg catgagtgcg
     5041 gtaatcagga aagtgcttca tgtgacagag gaaaatgcag ctgcgggcgt aaggcagaaa
     5101 atggaagttc agaggatatg acgcctcctc gctcactcag tcgctgccgc tcctgccgtt
     5161 cggctgcggc gggcgttacc tgcacacgga gaagagcgaa ggcatatggc atgacaaacg
     5221 gggcagaaaa aggatgcgcc gctgccg
//
