LOCUS       NC_013324              29646 bp    DNA     circular CON 10-SEP-2023
DEFINITION  Staphylococcus aureus plasmid SAP027A, complete sequence.
ACCESSION   NC_013324
VERSION     NC_013324.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225431
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 29646)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
  REMARK    Protein update by submitter
REFERENCE   2  (bases 1 to 29646)
  AUTHORS   Gill,J., Borman,J., Shetty,J., Hostetler,J., Durkin,S. and
            Montgomery,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2009) J. Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 29646)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/10/2023 03:58:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 33
            CDSs (total)                      :: 33
            Genes (coding)                    :: 27
            CDSs (with protein)               :: 27
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 6
            CDSs (without protein)            :: 6
            Pseudo Genes (ambiguous residues) :: 0 of 6
            Pseudo Genes (frameshifted)       :: 2 of 6
            Pseudo Genes (incomplete)         :: 4 of 6
            Pseudo Genes (internal stop)      :: 2 of 6
            Pseudo Genes (multiple problems)  :: 2 of 6
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GQ900388.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..29646
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="NE 3828"
                     /db_xref="taxon:1280"
                     /plasmid="SAP027A"
                     /geo_loc_name="USA"
                     /identified_by="Kenneth Bayles: Department of Pathology and
                     Microbiology, University of Nebraska Medical Center, Omaha,
                     NE, USA"
                     /note="human clinical blood isolate"
     gene            complement(join(29299..29646,1..582))
                     /locus_tag="HHF42_RS00005"
                     /old_locus_tag="SAP027A_035"
     CDS             complement(join(29299..29646,1..582))
                     /locus_tag="HHF42_RS00005"
                     /old_locus_tag="SAP027A_035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(698..1579)
                     /locus_tag="HHF42_RS00010"
                     /old_locus_tag="SAP027A_001"
                     /pseudo=""
     CDS             complement(698..1579)
                     /locus_tag="HHF42_RS00010"
                     /old_locus_tag="SAP027A_001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(1576..>1953)
                     /locus_tag="HHF42_RS00015"
                     /old_locus_tag="SAP027A_003"
                     /pseudo=""
     CDS             complement(1576..>1953)
                     /locus_tag="HHF42_RS00015"
                     /old_locus_tag="SAP027A_003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(2011..2685)
                     /locus_tag="HHF42_RS00020"
                     /old_locus_tag="SAP027A_004"
     CDS             complement(2011..2685)
                     /locus_tag="HHF42_RS00020"
                     /old_locus_tag="SAP027A_004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            3159..4625
                     /gene="msr(A)"
                     /locus_tag="HHF42_RS00025"
                     /old_locus_tag="SAP027A_005"
     ARG             3160..4622
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4724..5623
                     /locus_tag="HHF42_RS00030"
                     /old_locus_tag="SAP027A_006"
     CDS             4724..5623
                     /locus_tag="HHF42_RS00030"
                     /old_locus_tag="SAP027A_006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            6109..6717
                     /locus_tag="HHF42_RS00035"
                     /old_locus_tag="SAP027A_007"
     CDS             6109..6717
                     /locus_tag="HHF42_RS00035"
                     /old_locus_tag="SAP027A_007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583527.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRDYDEIIETVSYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGSS"
                     /name="recombinase family protein"
     gene            complement(6927..7493)
                     /gene="qacR"
                     /locus_tag="HHF42_RS00040"
                     /old_locus_tag="SAP027A_008"
     ARG             complement(6931..7493)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            7671..9215
                     /gene="qac"
                     /locus_tag="HHF42_RS00045"
                     /old_locus_tag="SAP027A_009"
     CDS             7671..9215
                     /gene="qac"
                     /locus_tag="HHF42_RS00045"
                     /old_locus_tag="SAP027A_009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_002449598.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIVSSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFVIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMTSVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGTASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            9420..9980
                     /locus_tag="HHF42_RS00050"
                     /old_locus_tag="SAP027A_010"
     CDS             9420..9980
                     /locus_tag="HHF42_RS00050"
                     /old_locus_tag="SAP027A_010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(10296..11039)
                     /locus_tag="HHF42_RS00060"
                     /old_locus_tag="SAP027A_011"
     CDS             complement(10296..11039)
                     /locus_tag="HHF42_RS00060"
                     /old_locus_tag="SAP027A_011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            11465..12448
                     /locus_tag="HHF42_RS00065"
                     /old_locus_tag="SAP027A_012"
     CDS             11465..12448
                     /locus_tag="HHF42_RS00065"
                     /old_locus_tag="SAP027A_012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <12468..12757
                     /locus_tag="HHF42_RS00070"
                     /pseudo=""
     CDS             <12468..12757
                     /locus_tag="HHF42_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(12956..13336)
                     /locus_tag="HHF42_RS00075"
     CDS             complement(12956..13336)
                     /locus_tag="HHF42_RS00075"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(13621..14313)
                     /locus_tag="HHF42_RS00080"
                     /old_locus_tag="SAP027A_015"
     CDS             complement(13621..14313)
                     /locus_tag="HHF42_RS00080"
                     /old_locus_tag="SAP027A_015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            14423..14617
                     /locus_tag="HHF42_RS00085"
                     /old_locus_tag="SAP027A_016"
     CDS             14423..14617
                     /locus_tag="HHF42_RS00085"
                     /old_locus_tag="SAP027A_016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            15733..16350
                     /gene="cadD"
                     /locus_tag="HHF42_RS00090"
                     /old_locus_tag="SAP027A_018"
     ARG             15734..16347
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16369..16716
                     /locus_tag="HHF42_RS00095"
                     /old_locus_tag="SAP027A_019"
     CDS             16369..16716
                     /locus_tag="HHF42_RS00095"
                     /old_locus_tag="SAP027A_019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            16873..16965
                     /locus_tag="HHF42_RS00100"
     CDS             16873..16965
                     /locus_tag="HHF42_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17137..18108)
                     /locus_tag="HHF42_RS00105"
                     /old_locus_tag="SAP027A_020"
     CDS             complement(17137..18108)
                     /locus_tag="HHF42_RS00105"
                     /old_locus_tag="SAP027A_020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            18232..18651
                     /locus_tag="HHF42_RS00110"
                     /old_locus_tag="SAP027A_021"
     CDS             18232..18651
                     /locus_tag="HHF42_RS00110"
                     /old_locus_tag="SAP027A_021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(19177..20022)
                     /gene="blaZ"
                     /locus_tag="HHF42_RS00115"
                     /old_locus_tag="SAP027A_022"
     ARG             complement(19181..20022)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            20129..21886
                     /gene="blaR1"
                     /locus_tag="HHF42_RS00120"
                     /old_locus_tag="SAP027A_023"
     ARG             20130..21883
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            21876..22256
                     /gene="blaI"
                     /locus_tag="HHF42_RS00125"
                     /old_locus_tag="SAP027A_024"
     ARG             21877..22253
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            22520..23098
                     /locus_tag="HHF42_RS00130"
                     /old_locus_tag="SAP027A_025"
     CDS             22520..23098
                     /locus_tag="HHF42_RS00130"
                     /old_locus_tag="SAP027A_025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            23768..24442
                     /locus_tag="HHF42_RS00135"
                     /old_locus_tag="SAP027A_026"
     CDS             23768..24442
                     /locus_tag="HHF42_RS00135"
                     /old_locus_tag="SAP027A_026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(24611..25182)
                     /locus_tag="HHF42_RS00140"
                     /pseudo=""
     CDS             complement(24611..25182)
                     /locus_tag="HHF42_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(25458..26252)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HHF42_RS00145"
                     /old_locus_tag="SAP027A_028"
     ARG             complement(25462..26252)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(26345..26875)
                     /gene="sat4"
                     /locus_tag="HHF42_RS00150"
                     /old_locus_tag="SAP027A_029"
     ARG             complement(26349..26875)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(26872..>27507)
                     /locus_tag="HHF42_RS00155"
                     /pseudo=""
     CDS             complement(26872..>27507)
                     /locus_tag="HHF42_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(27648..28322)
                     /locus_tag="HHF42_RS00160"
                     /old_locus_tag="SAP027A_032"
     CDS             complement(27648..28322)
                     /locus_tag="HHF42_RS00160"
                     /old_locus_tag="SAP027A_032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<28379..28555)
                     /locus_tag="HHF42_RS00165"
                     /old_locus_tag="SAP027A_033"
                     /pseudo=""
     CDS             complement(<28379..28555)
                     /locus_tag="HHF42_RS00165"
                     /old_locus_tag="SAP027A_033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(28569..29306)
                     /locus_tag="HHF42_RS00170"
                     /old_locus_tag="SAP027A_034"
     CDS             complement(28569..29306)
                     /locus_tag="HHF42_RS00170"
                     /old_locus_tag="SAP027A_034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     ARG             7672..9212
                     /name="qacB"
                     /gene="qacB"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacB"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.61"
                     /coverage="100.0"
     ARG             4725..5620
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             3160..4625
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             4725..5623
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(26346..26863)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(19178..20022)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             complement(27170..27471)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          12814..12961
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(10297..11039)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11466..12448
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12580..12749
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 atgacttgaa attaaaatgg ttatatttct agattgagcc agatccttaa tcaactttct
       61 aatttctttt atgccaatag gatctaatcc attcgtcggc tcatcaagta tcaataattc
      121 gggattgtgc aataaagctc tcgcaatccc taaacgttgc ttcataccta aagaataatt
      181 tttaaacaat tttacttttt cagaagctag tcctactatt tctaacactt cttcaattgc
      241 attttctttt tgtataccta atattttagc atttatagtt aagttctctt tagctgtcaa
      301 attactataa aaacctggcg tttcaaccat agcaccaata ttttttaaaa tttcagtttt
      361 attactttcg aactcttttt caaatatttt aatattacct ttcgtaggtt taattaagcc
      421 taaaagcatt cttatagtag ttgttttgcc tgcaccattt cttcctaaaa aaccataaat
      481 ttgtccactt tcaacagtta tactcaaatt attaactgct atctgacttc catattgctt
      541 tgttaagtta tttatttcaa ttatattatt caaatttttc acctctggca cctttcttag
      601 tttgttgtta cctttatctt acgcgcgatt agaaaaggct gcctttatct attcttacaa
      661 aaacagccgc taatcttaca aaaatgaaag attggagtta tttaaattga atggtgaata
      721 ttgaaccatc gtttaatgta gatgtagcac ttactttatg gcctaagcgc tttgagattg
      781 tgctgacaat atataaacca ataccgcttg atttctcact tattctaccg ttatagcccg
      841 agaaaccttt atcaaagatt ttcggtaaat cactcgcatt aatgccgata ccgttatctc
      901 ggattgataa tttctttgta ttttcgtcaa acgtaatcca cacatctttg ccacgtgcat
      961 attttaatgc attgtttaat atttgctcaa tcataattga tgcccatttg gcatctgtta
     1021 atataaccgc ttcacttttc tcataatgca actttgtttg atgatgaata aactgtatcg
     1081 cataacgttt aatcagtggt cgaattaatt catctacact cacttccata aagaccatgt
     1141 atgtcttttg gttcatgagt ttcaaatagt tcagtgcaag attcgtgtaa ttatcaattt
     1201 gtaagacttc attacgcacg ttagaaatca cgtgttcatc aggatcttca agcagtaact
     1261 ttgatgctgt aatcggtgtc ttgatttgat gcacccacat taaaaaatat gactctaact
     1321 cactttggta gttaataaag tcattacgaa gtttatggtt ttcgattctt aaatcttcgt
     1381 tctgttcctg tagtgtttat tcttttttaa agttcatgta atggataccc cagtaaatca
     1441 ttgaaacaaa caatacaata cctagaccaa tcatatatgc ttgcatcggc acattataca
     1501 tgaataatat aaagtagaat aaagcacaag taaggatgac aatataaatt tcacgttgga
     1561 ttgatttcaa gaaattcata cgtcacctac acgatatccg acatttttct tcgtttcgat
     1621 aaaatctgta agtcctagtt tttgtagctt tttgcgtaaa cgtgtaatgt tgacagcaag
     1681 cgtattgtca tcaatgaagt gttctgattc ccagcatttt tcgattaacg cattacgact
     1741 gacgaatttg cccttgttct ggaataagct atgcatgatt tgcaattcag tgtgtgtcag
     1801 gtctatggtt tcttcattaa atttaagctt tgctgcatca agtagtaact cgcaatcatc
     1861 tactgttaaa ttattaactt gagtggtgaa atcatacgtg cggcgtaata gtgcttgaat
     1921 cttagtaatt gtaacagtca tattaaatgg ctggttctgt tgcaaagtaa aaaatatagc
     1981 taatcactaa tatatcatgt cagtgttcgt ttaacttgct agcatgatgc taatttcgtg
     2041 gcatggggaa aatccgtaga tctgaagaga cctacggttc tttttatata gagcgtaaat
     2101 acattcaata ccttttaaag tattctttgc cgtattgata ctttgatatc ttgtctttct
     2161 tactttaata tgacggtgat cttgctcaat gaggttattc agatatttcg atgtacaatg
     2221 acagtcaggt ttaagtttaa aagctttaat tattttagcc attgctgcct tcgttgaagg
     2281 tgcctgatct gtaactacct tttgaggctt accaaattgt ttaatgagac gtttgataaa
     2341 cgcatatgct gaatgattat ctcgttgctt acgcaaccaa atatctaatg tatgtccctc
     2401 tgtatcaatg gcacgatata aatagctcca ttttcctttt attttgatat acgtctcatc
     2461 aatacgccat ttgtaataag cttttttatg ctttttcttc caaatttgat ataaaattgg
     2521 ggcatattct tgaacccaac ggtagatcgt tgaatgatga acgtttacac cacgttctct
     2581 taatatttca gatatatcac gatagctcaa tgcatatctt agatagtagc caacggctac
     2641 agtgataaca tccttgttaa attgtttata tctgaaatag ttcatacaga agactccttt
     2701 ttgttaaaat tatattataa attcaacttt gcaacagaac cgtattttat gagtacactc
     2761 taaattaagg agatgtataa tcaatctaaa attgtatttt tatacttttg ttatataatc
     2821 tttctactta gagatatatt gtaaaaaaac caacaaaatg ttatattaac attactattt
     2881 tatcgatgaa ggaggattaa aatgacagct tctatgagac tcaaataaac ctttttgaat
     2941 acaaaactaa attaattcaa aaaggcttgt ccgcaataca cactcatagg atgacttatg
     3001 tcatttttta tccttcgata ggaataataa acgctttcaa atactaaaac atcataataa
     3061 atttttaagt gtttgaaagt gtaatgtgaa tgagacggga gtagcctgtc tcattttttt
     3121 gcgtacacgt cctttaaata tacaaggagt gtataaatat ggaacaatat acaattaaat
     3181 ttaaccaaat caatcataaa ttgacagatt tacgatcact taacatcggt catctttacg
     3241 cttaccaatt tgaaaaaata gcacttattg ggggtaatgg tactggcaaa accacattac
     3301 taaatatgat tgctcaaaaa acaaaaccag aatctggaac agttgaaacg gttggcgaaa
     3361 ttcaatattt tgaacagctt aacatggatg tggaaaatga ttttaacacg ttagacggta
     3421 gtttaatgag tgaactccat atacctatgc atacaaccga cagtatgagt ggtggtgaaa
     3481 aagcaaaata taaattagct aatgtcatat caaattatag tccgatatta cttttagatg
     3541 aacctacaaa tcacttggat aaaattggta aagattatct gaaaaatatt ttaaaatatt
     3601 actatggtac tttaattata gtaagtcatg atagagcact tatagaccaa attgctgaca
     3661 caatttggga tatacaagaa gatggcacaa taagagtgtt taaaggtaat tacacacagt
     3721 atcaaaatca atatgaacaa gaacagttag aacaacaacg tcaatatgaa cagtatataa
     3781 gtgaaaaaca aagattgtcc caagccagta aagctaaacg aaatcaagcg caacaaatgg
     3841 cacaagcatc atcaaaacaa aaaaacaaaa gtatagcacc agatcgttta agtgcatcaa
     3901 aacaaaaagg cacggttgag aaggctgctc aaaaacaagc taagcatatt gaaaaaagaa
     3961 tggaacattt ggaagaagtt gaaaaaccac aaagttatca tgaattcaat ttcccacaaa
     4021 ataaaattta tgatatccat aataattatc caatcattgc acaaaatcta acattggtta
     4081 aaggaagtca aaaactgcta acacaagtac gattccaaat accatatggc aaaaatatag
     4141 cgctcgtagg tgcaaatggt gtaggtaaga caactttact tgaagctatt taccaccaaa
     4201 tagagggaat tgattgttct cctaaagtgc aaatggcata ctatcgtcaa cttgcttatg
     4261 aagacatgcg tgacgtttca ttattgcaat atttaatgga tgaaacggat tcatcagaat
     4321 cattcagtag agctatttta aataacttgg gtttaaatga agcacttgat cgttcttgta
     4381 atgttttgag tggtggggaa agaacgaaat tatcgttagc agtattattt tcaacgaaag
     4441 cgaatatgtt aattttggat gaaccaacta attttttaga tattaaaaca ttagaagcat
     4501 tagaaatgtt tatgaataaa tatcctggaa tcattttgtt tacatcacat gatacaaggt
     4561 ttgttaaaca tgtatcagat aaaaaatggg aattaacagg acaatctctt catgatataa
     4621 cttaaaaact atacactaat ttatattgaa tattaggttc atttatatca atataaaaaa
     4681 tacgttcaca agaaaaatat aatagaaata aggatccaat aaaatgactc gacataatga
     4741 aattattaaa tgtgcagaaa aatatcaatt acacatccaa cctcaaacaa tctcattgaa
     4801 tgaatcggga cttgattttc aagttgcatt tggaaaagat aaacatggag tagaatgggt
     4861 tttgagacta ccaagaagac ctgacgttta taaacgaaca aaacccgaaa aacaaacggt
     4921 agacttctta cagaagaatg tttcatttga aataccgaag tggaaagtac atgcaaaaga
     4981 ccttattgct tacccaaaac ttacaggtaa acccgcagcc acaatagatc cagaaataca
     5041 aaattatgta tgggaaattg aacacaaacc attaccagaa aactttatta acacattagc
     5101 tgaaacactc gtagatttac acaacatacc agaagaaaac attaacgttc agcatataaa
     5161 tatcaaaacc atacaagaaa taaaaaatga ctttcaaaga agaatgaata aagttaaaga
     5221 aacttatggc gtatcagatg aattatggaa cagatggaaa caatggttag aaaacgacga
     5281 actatggcct cgacatgcga ccatgataca tggggactta catccaggac atataatggt
     5341 agataaccaa gcaaacgtca caggtctcat agactggact gaagcaaccc actccgaccc
     5401 atcaatggac tttataggac accatcgtgt attcgacgac gaaggattag agcaacttat
     5461 aacagcatac ggtaaagctg gaggtgaaat atggccacga atgaaagagc atataataga
     5521 actcaatgca gtattcccaa tgtttatcgc tgagtttgct atggaatcag gagaatcggc
     5581 gtatgaaacg atggcattga aagagttagg tatgaaagag tagaacttat attaaaagag
     5641 gcccatttta aagacgaagg caatcctgat gaaattttaa aactgcgttt aattagtgat
     5701 ggtctttggt tttctataat gtattaaata tctggacatg gaacaaatgc aacaaatgga
     5761 aagaatcgtt ttcgaaattt ctaactcctt aaatcaggag gataaataaa cggtcatttt
     5821 cattgaaagc acttatataa atttcatcaa ttttaatacc taccgtaaat acatttcata
     5881 agtattaaac agatgattaa aatttttagt taatttaaat atttatgata gagatgacct
     5941 tcaaatgaac ggttctgtta caaagaaaaa atctatattt atttttagta agttttaatt
     6001 atagatatgt acactttgag tacaccctaa tcatacaaaa taagttgttg aaattatcgc
     6061 aattagaacg tatgattagg gtgtatatta attatggagt gaagatgaat gattataggt
     6121 tatgcgagag tatcatcgat agatcaaaat ttagaaagac aattggataa tttaaagacg
     6181 tttggtgtgg agaaaatctt tacagagaaa cagtcgggaa agtcagtgga aaatagacct
     6241 gtatttcaag aagcactcaa ttttgtcaga atgggagatc gattcgttgt ggaatctatt
     6301 gatcgtttgg gacgtgatta tgatgaaatt attgaaactg tgagttattt aaaagagaaa
     6361 gacgttcagt taatgattac cagcttacct atgatgaatg aagtgattgg caatccatta
     6421 ctggataagt ttatgaaaga tttaatcgtt caaattttag caatggtttc agaacaagag
     6481 agaaatgaaa gtaaacgtcg acaagcgcaa ggaattcaag ttgcgaagga aaaaggcgta
     6541 tataaagggc gccccttact ttattcacca aatgccaaag acccacagaa acgtattatt
     6601 tatcatcgcg tggtggaaat gttagaagaa gggaaagcaa ttagtaagat tgcgaaagaa
     6661 gttaatatca caagacagac agtttataga attaagcatg ataagggatc atcttgataa
     6721 atgggtcgtc aatgcaaata agaggctctc acagagtctc aaaactcata ttatattatt
     6781 gaaatgatct tttaataatt atacaagaaa aaagagagtg cgaattcgca ctctcttttt
     6841 gtgtagtaat actatttaaa ttttttatca ataatgaacg taatttagaa ataatattta
     6901 ttggtatttc aagaatatat atataattat ttactaagtc catttaaaaa aatttgagag
     6961 aacttgttca taagtttaat tctttcatta atattttgtt catgtgtaaa ggtaacaatt
     7021 ccattaacag cgtttgctgc tattttacta acagcattaa catcattaat acaccattcg
     7081 ccatttaaat taccctcctt aaaaattaca tgataagcat ctatatattt gttttctaat
     7141 ttattcattt tttcattaat gctattagtt ttataatatt cagtgcaaaa ttcaattatt
     7201 gcgttttgaa gtggataata gtattcggtt gttaaagata gttcattata taaataaaat
     7261 ttttctctat tagttttaca tttgatttgt tcctttttcc actgttcttg ccatttagat
     7321 tcttctatat ttaaaatttc taaaaataga ttttcttttg ttttaaagtg ataataaaga
     7381 ttccctttac tactttctga taatttaaca atttctccag tagtagtggc attatatcca
     7441 ttttttataa ataattcctt tgcgacacct agtattttat ctttcaagtt catcacgcct
     7501 ttaatgagta ttaagtacta tcaatgatag cacaaaaaat tcaaagaata attgtataac
     7561 acaatacagc catttaaatt tcgcaagatt ttttgttgta atatgtaaaa aaatagatta
     7621 taatccttat agaccggtcg aacggtctat aaggattgga gggaacttaa atgatttcat
     7681 tttttacaaa aactactgat atgatgacat caaaaaaaag atggactgca ctagtagtat
     7741 tagctgttag tttgtttgtt gttacaatgg atatgacaat attaattatg gctttaccgg
     7801 aattagtaag agagttagag ccttctggta cccaacagtt atggatagtt gatatatact
     7861 ctcttgtttt agctggcttt ataattccat tgagtgcctt tgctgataaa tggggaagaa
     7921 aaaaagcatt attaactgga tttgctttat ttggcctcgt ttcattagct atatttttcg
     7981 cagaaagtgc agagttcgta atagctattc gatttttact tggtattgca ggtgctttaa
     8041 taatgccaac tactctttca atgataagag taatttttga aaaccctaaa gaaagggcca
     8101 ctgcattagc tgtatggtca atcgtttcat cgataggtgc tgtttttgga ccaattatcg
     8161 gaggagcttt acttgagcaa ttttcatggc actcggcatt tttaattaat gtaccgtttg
     8221 tgataatagc agttgtagca ggtttatttt tattaccaga gtctaagtta tcaaaagaaa
     8281 agtctcactc gtgggatatt ccttctacaa ttttatcaat tgcaggcatg attggactgg
     8341 tatggagtat caaagaattt tcaaaagaag gactagcaga tattattcca tgggttgtaa
     8401 tagtattagc aattaccatg atagtgatat ttgttaaacg taatttatca agttctgatc
     8461 caatgttaga cgtaagactt tttaaaaaga gatcattttc agctggtaca attgctgcat
     8521 ttatgacaat gtttgcaatg acatctgttt tgttattagc ttcacaatgg ttacaggttg
     8581 tggaagaact ttctcctttt aaagctggct tatacctatt acctatggca ataggagata
     8641 tggtgtttgc accaattgca cccggattag cggcgcgatt tggaccgaaa atagtgttac
     8701 cttccggaat tggaattgca gccattggca tgtttattat gtatttcttt ggtcatccat
     8761 tatcatattc tacaatggct ttagcattaa ttttagttgg agctggtacg gcttcactag
     8821 cagttgcatc tgctctaata atgttagaaa cacctacatc aaaagcaggt aatgcagctg
     8881 ctgttgaaga gtctatgtat gaccttggaa atgtttttgg tgtagcagta cttggtagcc
     8941 tatcttctat gctttatcgt gtatttttag atatttcatc tttttcatca aaaggtatag
     9001 ttggagattt agctcatgta gctgaagaat ctgtagtggg cgctgtcgaa gtagctaaag
     9061 ctacggggat aaaacagctt gcaaacgagg ctgtaacatc atttaatgat gcttttgtag
     9121 caactgcttt agtaggtggg attatcatga ttatcatttc aatagttgtc tatttgttaa
     9181 ttcccaaatc acttgatata actaaacaaa aatagtacta aacatatatt tttagatatt
     9241 gtagattagt ttatttttaa aattagtaat agttaaaaag tagaaccatt aattttaaat
     9301 ggttctactt ttttattatt aagtaaaatt ataaaagaca atttcttaaa ttaataatat
     9361 gatataccta tatctaataa tttattagta ttaataaacc ttgaaaggat gattaactga
     9421 tgaatagagc agatattttt aaaatatttg atgtagaact taatataact atatttttag
     9481 gagcactagt agcaactttc atctatttta taagttacat gaacaatgta aatgaattaa
     9541 ttacattatg cttaacatta gcttttcctg catatttatt aaaaattagc agatcgttcg
     9601 aggttatttt attagaggaa aaaataaaaa atagtaaaat caaaatctgt gacaaagata
     9661 gaattgaacg agagatactg gtgaaaaaga acctaataga tgaactattg tttcctaata
     9721 gagttattaa aaaatataca ctgacaattt taatttacag tataggtatt attattcttt
     9781 tactactttg taatatgtta agttatggaa ttggtgaaaa tgtcaatttt atctggagat
     9841 tactagcttg ttatgtaacg agtgtcacag tgattatagt tgccttgatt ataatgataa
     9901 tgatatttga tcttataatt ggattactat taaattttca aatattttta aaaaataaaa
     9961 agtatgatga ctttttataa ttattcgatt tatataatga aaaattaaat gattaaacat
    10021 agaaacctca aaacaaacca tatttaatag agtttatggc gccttataca aataaaggct
    10081 atgctgttaa agaattatgt agctatcttc agattaatat ggatgatgtt tatactattg
    10141 gcgatagaaa attgatttac ctatgtttaa taccctagat aattcttctg ataatttagt
    10201 ttttgttaga gtttaacata actgatgatt accagaagtt ctcactatat aaaagacact
    10261 aaaattttat aacttttagt gcctaatcaa ttattttagc taccaaacaa acgactccaa
    10321 aacccctttt taggttccgt ttcttcactc ttttcttcta tatcactatc attgtcattt
    10381 agattagctg gaacgtcttc tttttttgct tcttcacctt gtgtactttc gtcgctttga
    10441 cttccagata tatccttata ttgaatctct gtttctttag tttcttcctg atctctgtta
    10501 atatttacag gattagtagt atatgttttt tcttgtgcat caacgttttg tctagtgtta
    10561 gtagatgtat caaagggata attaaggtgt ttttcttttt ctaattgatt ttctaatttt
    10621 tgaatctttt tattactctc taatgccaga acttgctgat tttcaagcaa ttttgatctt
    10681 tcttgcaact cttttctgta aaattcaatt gttgtttcat gacgactttc ttgtttttca
    10741 atttgattat ttaaagtatc aatctgattt ttaaggattt ctactatttg agcatcgctt
    10801 ttcgattcaa aattaatatt atccgaccct tttttttgtt tgtcttcagt agtactttca
    10861 aaaccatatt tctttttatt ttcatttact ctttgaatga ttttttctat atcggtatct
    10921 tctttaataa acgaagtgtt ttcctgtttt attgtctcta tattcaatcg cttaatatta
    10981 ttaaaaatcg tttgcttact aacccctaat tcttcactca actttttcac acttttcata
    11041 tcatcaaccc tttataaaat gtttataaac ccttgataaa atattataag cttataatgc
    11101 ttaataataa agtgattaat aaataaaaat aaacatccat caaccttttt atcaagggtt
    11161 tatgaaaggt ttatgatatt tatcaagggt ttataaaccc ttgataaagc tatattttcc
    11221 cttttataag tttatttaaa gtgctataat aaacttaata taacaaaaac cccaactact
    11281 ggtaatagtc ggggtttggt aataaaacgt ttagaaactg tttatttata taattttcga
    11341 tacttgtatt atataatgaa taatatctta gtgcaagcac ctaaatcatt aaataaatgt
    11401 aaagctaaat aaaaacgttt tattacctct taccaaacta aaatatggaa agaggttttt
    11461 tgtcatgcaa aatcaatatt ttacagtgca agaaaattac aaagaaagat tttatcaaat
    11521 ccctaaagta ttctttacca gtgaaaatta taaaaatcta actaatgata tgaaaatagc
    11581 ctatgctatc ttacgtgatc gcttaaattt atctattaaa aatagctggg ttgatgaaga
    11641 tggtaacatt tactttgttt attcaaatga aaagctaatg gaaatcttaa attgtaaaaa
    11701 agaaaagtta acaaaaataa aaaaagggtt agaaaacgat ggtctactca ttcaaaaacg
    11761 acgtggttta aataaaccaa atattctata tttaatgaaa cctattgtca cagaacgtga
    11821 tatttacaaa atagaaaaag aagaaaacga tgttgaacct tacggcgaga aggaagttcg
    11881 aaaatcgaac gtccagaagt tcgaaaatcg aacgtccaga agttcgaaaa tcgaacgtcc
    11941 agaagttcga aaatcgaaca ctaatgatac tgactttaat gacattgact ttaatgatac
    12001 tgagaataat gatatgaatg acttgaatga tataaagtac aaaaatgaaa ttagtaatca
    12061 ttcaaatcat tcaaatcaat ttacacataa ttttgatgat aaagaaatgc tattgcaaga
    12121 attcccagaa caactaacta attatttatt aaaatatgat tatagagatt tagaaatcat
    12181 aaaggctgtt attcttaaag caaaaaaatc atttaattca aggcatgaag atatgcatta
    12241 catgttagag gacattgagg atgaaatatt aacttcttta aaaagactta aaaaagctat
    12301 acatgatagg ggagttaaag gccaaaagga aacaatcaag tcaatgcaag cttatttaat
    12361 gcaaacaatt ctaactgaac ttgaagaaac acatgccctt tatatgcgcc gtaaaaacat
    12421 gaaacaatat aatatcttta atcaataatt caaatgattt tataacactc gaagagacat
    12481 caaaatattc cgttaaatca tctgactttt taactgatga cgacgaaaaa aatcaagaaa
    12541 ttgtaagtga tttagaaaaa ggtttgtatc gaaaacgtat gttaagttat ggtggattgc
    12601 ttaaacaaaa gcataaaatt ttaaacttag acgatgccga agatggtaat ttgattaata
    12661 caagtgatga agataaaacg acagacgaag aaaaaaagca cattcaatta ccgcaatttg
    12721 gaatttcgaa aagcaaaatt attatttaag acattagtga taactgatgt ctttttttat
    12781 tgtttttctg taaaaaagtg ctgtcttatt tttgtgacaa atgctgtatg tagtgtcaca
    12841 aaagtgtgac actacagctt tgtatgatat cactttaaaa taacttaaaa cccttggaat
    12901 gtctggcctt gccagatcta tcatttttga atgatagcaa atttccctta tgctcttacg
    12961 gagattttag agttaaatta aaatttctaa gtttttgata agaaaagccc tgcaggaatt
    13021 tagaaaaaca tggggaagtt ttaaagtatt ttatgctaat ttttaaattt gcatgtaaat
    13081 gggcagtatc taaaaaatta gtcactgatt ttgctgaaat ttttgtttgt gaaattagca
    13141 tatatttatt tggctcatat ttgcgtttta agagactgta tagattttta agtacaaaac
    13201 ctatatgatt tgcctctaag tcttcaaaat gcctcttaaa atccaaaata aaagtgttta
    13261 atattgtaat aaggattgct atttttataa aaggagagat atcatgaaga ttaaaacttt
    13321 cgctactttt actcatcgtc aattagataa acaagttaat aggtttttaa agaatgatat
    13381 tcatgtatta gaaattcaaa cacacagtaa ttggttatat atttcagcta ttgtttttta
    13441 tgaggataaa taaggaacat cgtatttatg ccgaaaaaat ttattgatgt tgagaagaac
    13501 ccttaactaa acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga
    13561 caagttttgg gattgttaag ggttccgagg ctcaacgtca ataaaacaat tggaataaaa
    13621 tcaacctaca gagcatccag ctgcaaatgc agttccgcaa actgcttcac atacaccgcc
    13681 ggctattgga tttacgattg cccatactcc acagtagtga gcacatgcat aaagtccagc
    13741 catactacaa gcgaatgctt tgccgttcca tttgaatcct gcatatgtta ccggtctgtt
    13801 tttatcaact ttttcagcct tatattcaac gtaatttttg ttaataagta tttttccctc
    13861 tttgttttca gtcatacttc ttttttcggc aatgaatttt gtgatttttt tgttgtagtt
    13921 atcatatatt gtttcagaaa ctacaatttc ttttgttttt tcatttttat aagcgttatt
    13981 agctatgtag ccatatgcat ttttatcatt tgcttctgta gctagatatt ttaatttaga
    14041 atttttgtct tctagcttta tttttttaaa tccttctttt ttcatttgct tttcgaattt
    14101 ttgcatatct tcatttttat tttgcaattg ttctagaaaa cttatttctt tcttggtcat
    14161 ttgtgatact tcgatgtttt tgcttttcaa tttttctttt tgattttcta gtaaagaact
    14221 tttttgttct tcatttgcgt aagcattaga aaaattcgcg ctaaatacca gtaggaacaa
    14281 ggaaattatt gaaaataatt ttataatttt catttgatac ctccaagata ataagatatt
    14341 ttaattgtat aagtaagcgc tttataaaat caatatttat tttaatatat ttataaacat
    14401 atttttgaaa ggagtctatt ttatgaatga aaatttagaa aaatatataa aaagtttgcc
    14461 acttttaggt ttgttaatta gtattttgtt aattgtttta ttctttttta ttttagatgt
    14521 tgatgaagat ttattcgtgg tttttttata ctgtttattg cctttgatag ttaatttgtc
    14581 tatttatggt ttttatgttt ttgttaaaag aaagtaagat tatgaataat tttgttttta
    14641 atttgtatgc tttgaggggg ttggaaaacg gtaggtgtat agattagatt tcttgttttt
    14701 ttgaaacgag tgtgaacgag tttcttcttg tcttgatttt tgataaaaac gccctacagg
    14761 aatttagaaa aacgtgggga agttttaaag aattttatgc taatttttaa tttgcatgta
    14821 aatgggcagt gtctaaaaat agttattgtt tttgctcaaa tttttgtttt tgaaaatagc
    14881 atatatttat ttggctcata tttgcgtttt aaaagcatat ataagtttta gatataaaac
    14941 tatatgaatc acccctaaat ctttaaaatg ccctcttaaa attcaaaata agggcataaa
    15001 aaataaaagc taccccagat aaagtgaggt agctttttct ttcatacggt ctatttattt
    15061 ttctttcgac gccgtatcgt cgatgtaatt caaaaaagtt atgggctata aatctacatc
    15121 actttttcaa gaatgtagta gcaatattca acgcaaatta atttttataa ctgctcggaa
    15181 tatctcaagc cgtttcttta attttgaaat aaaaaaatcg acgaaggtcg attacgtttt
    15241 tgcacatgtc gatttatccg acgtataagt gcgcccttac gggatttaac tagattataa
    15301 cgacgaattt tagacctgta aagcaataac aattaggtct accaggtaga taaagtgtac
    15361 aaagtagaac cgaaaaagtt atttattttg aagatttttc gtagatataa tttgctaata
    15421 aacttcctaa aactgaataa agaaaaatag ttaaactcat gtaatcactc cataattctg
    15481 aagtgtctcc atgtctacgc atagacacgc atttatgccg aaaaaattta ttgatgttga
    15541 gaagaaccct taactaaact tgcagacgaa tgtcggcata gcgtgagcta ttaagccgac
    15601 cattcgacaa gttttgggat tgttaagggt tccgaggctc aacgtcaata aagcaattgg
    15661 aataaagcac ctatgattat ttaaaaatat aagttataat acattcaaaa atatttttga
    15721 gtgaggtgta ttatgattca aacggttgtt gctgctgctg ttctttatat tgctacagca
    15781 gttgatttat tagtaatttt attaatattt tttgctagag caaagactag aaaagaatat
    15841 agagatattt atgttggtca atatttaggg tctattattt taatattagt tagtttgttt
    15901 ttagcttttg tattaaatta tgttccagaa aagtggatat taggtttatt gggtttaata
    15961 ccaatttatc ttggaattaa agtggctatt tatgatgatt gtgaaggaga aaagagagct
    16021 aaaaaagaat tgaatgaaaa aggattgtct aaattagttg gtacggttgc aattgttacg
    16081 atagcaagtt gtggcgccga taatattggt ttatttgttc cgtattttgt gacattaagt
    16141 gttactaatt tattacttac tctgtttgtc tttttaattt taattttctt cttggtgttt
    16201 actgcacaaa aattagctaa tattccagga attggagaaa ttgttgagaa atttagtcgt
    16261 tggattatgg ctattattta tatagcttta ggtttattta ttattattga aaatgacact
    16321 attcaaacaa ttttaggatt tatattttaa tttagggtgt gattttatat gagttatgaa
    16381 aatacttgtg atgtgatctg tgtacatgag gataaagtta acaatgcttt aagtttttta
    16441 gaagatgata aatctaagaa attacttaac attttagaaa aaatttgtga tgagaagaaa
    16501 ttgaaaatca tattatcttt gattaaagaa gatgagttgt gtgtttgtga tatttctttg
    16561 atattgaaaa tgagtgttgc ttcaacttca catcatttaa ggcttttata taaaaatgag
    16621 gtacttgatt tttataaaga tggaaagatg gcatattatt ttattaaaga cgatgaaata
    16681 agagagtttt tctctaaaaa tcatgagggt ttttgaaacg agtttcttct tgtcttgata
    16741 ctataaaaaa caaagttata taacataaga cgacttatcg gaagtagata tgcttgtata
    16801 ttcacagatg gtataataat agagtcgcct atctctcagg cgtcaattga cgaagagagg
    16861 aggtgcatta ctttgctaat cattttcgtt cacatcatag caccagtcat cagtggctgt
    16921 gctgttgcgt attatactta ttggcttagt aaacgcaaca aataattaat aggcgacttt
    16981 ataagccagc atcgaaaaaa tccccacact actgcaatag tgtggggatt ggtgcattaa
    17041 ttgttaatca ttttcgttat ataaattata acactggtta gtagagaaat gcaaaatgat
    17101 tgaattaata gtaaatgtat taatgaatac tcacacttat acttttaaaa tagttcttcc
    17161 taaatgttgt ccttttaaaa gctgatctat cgttttatag aattcttcaa atccaatttc
    17221 attgtataga agtgaatttc ctatattcca ttcatttgct aacttactcc atatatcttc
    17281 acggatatta tgatcaacat atacagaatc aatgccaatt aatttaatac ctctaagaat
    17341 aaacggtaat atattagcgt taagtgaatt tcctgctaca tttccacata cagtagcaac
    17401 accttgataa tttagacgtt ttaaaccgta taatgttaca ttactcccca ctgtatctaa
    17461 gaaataatca aaaatacctt ttttaagcgg tttattatca tcttcaatta ttattacttg
    17521 ttttgcacct aatttttttg cgatttctat ttgcttttct tttcttacga tagcagtgat
    17581 attttcatat ccaattttat gtaaaatttg tatagcaaca ctgcccacac cacctgtagc
    17641 cccagacact aaaatttcag gttgtgattt gatattcatt ccatattttt ctagttcaaa
    17701 aattgataat gctgccgtaa aaccggctgt gccatatacc atagactctt taatagacat
    17761 ttcttgggga ataggaacaa tccactctcc aggcacttgt gcatattctg aaaatccacc
    17821 tgtatgtgtc acgccaacat cataaccagt aactaataca ttatcgcctt ctttaaactt
    17881 atcattcgaa cttgattcaa caatacctgc aaaatctata ccaggaatca taggataatc
    17941 tctaattaca ccgcctttat attgtaaagc tagcatatcc ttataattta ttgaagagta
    18001 taccactttt actaatacat cacccttcga taaatgagat tcatcaactt tttctacttt
    18061 ataactaaca tttgatgcac tttttctcac tactaccgca ttgaacattt attagccttc
    18121 tttcacaatt gttttgtaga agtatgtttt tgttgcaaaa ctattttcct acaaaactta
    18181 tcatgatatg ataagcgagt caatactaat gatttaagag aggttttagt tgtggaatta
    18241 gataattgta taaattattt gttgagtact tctcagaata gagtttttaa acattttaaa
    18301 agtttattaa gtccctataa tattactcca gcagaatatg gtgttttgaa ttgcttgatt
    18361 aatagtaatt tgaatacacc taaagcgatt ggtaatactt taaatttaga accttcaaca
    18421 atatctggaa tattagataa gatgtccaaa aaggatctaa taacacgtca aactgataat
    18481 gaaaatagaa gaactgtgct aataaacagt acaaataaag caaaagactt atggccaaca
    18541 ttagaaaaga aagcctatca acttaataat cattacttcg ctaatttaac taatgaagaa
    18601 actgtagtgt ttaaaaagat attactaaag ataaataaaa ctacgtttta atttttacgt
    18661 tataaaaaag ttgaagtgcg aattataatc gagtaaatat aaatgatagc ttagcttaat
    18721 tatatattaa agccaactat acttttattc ccgaaaaacc tactatccaa atttctaaga
    18781 tactttagcc tctataataa acatattgta atataattta tgtattattt aggtttaccc
    18841 taatcgaaca ataaaaaata cttgtaaaat gctattgtca ctttgcttga tatatgagaa
    18901 ttatttaacc ttataaatga gaaaaaagca acgcacttta aataagatac gttgcttttt
    18961 cgattgatga acacctataa ttaaactatt catctattat ttatgatttt ttgtatatac
    19021 aatatttcta gtttgttaaa gagaattaag aaaataaatc tcgaaaataa taaagggaaa
    19081 atcagttttt gatatcaaaa ttatacatgt caacgataat acaaaatata atacaaacta
    19141 taagatgtta tcagtattta ttatgcattt agaatattaa aattccttca ttacactctt
    19201 ggcggtttca cttatcaact tatcatttgg cttatcactt ttattgtctt tattcgtaaa
    19261 aatgactaaa acaataggtt cagattggcc cttaggataa acaaaagcaa catcatttct
    19321 agaagcatat gttattgctt gaccactttt atcagcaacc ttatagtctt ttggaacacc
    19381 atctttaatt aaagtgtctc cgtttttatt attaaacatt aaatcaagta agaaattttt
    19441 attttttttg cttaattttc catttgcgat aagtttattt aaagtcttgc cgaaagcagc
    19501 aggcgttgaa gtatcttttt tgctctttgg tgaatagtaa tttaattcta tctcatatct
    19561 aactggattt gttactttat ctcctagttc ttttagacgt tgtttaactt ttttgattcc
    19621 accgatttct tttataattt tattgtttgc tgtattatca ctatatgtca ttgaagcctc
    19681 aataagttct tttaaagtga tatcttttcc tacatatttt tctaaaatag gagaataagc
    19741 aactatatca tctttgttaa tatgtacttt tttatttaac ttattataag gtacttgttc
    19801 taacaaaata gcactattta tcgcttttga agtcgaagca taggcaaatc tcttatctga
    19861 attaaatttt acttccttac cacttttagt atttaaagca taaacaccaa tatgagcatt
    19921 atattttttt tctaaatcat ttaactcttt ggcatgtgaa ctgtttgaat tacatgcact
    19981 taaaactaaa gcaattacaa ttaaaaatat taactttttc aaaataaacc ctccgatatt
    20041 acagttgtaa tttttataaa tcaataatat tacaattgta atattgatgt caattgttta
    20101 ttataaatat ttgaaagaag gtgtcaaaat ggctaaatta ctaataatga gcgtagtaag
    20161 cttttgtttt atatttctat tgttagtatt ttttaggtac atattaaaac gctattttaa
    20221 ttatagttta aattataaag tttggtatct aactatgctt gctggattaa ttccttttat
    20281 cccaattaaa ttctctttta taaaatttaa taatgtgaat aatcaagcgc ccacagttga
    20341 aagtaagtca cacgatttga accataacat aaataccacc aaacctattc aagagttcac
    20401 aacagatatc cataagttta attgggattc aattgataat atctgcacag ttatttggat
    20461 agttttagtt attattttaa gttttaaatt tttgaaagcc ttattatatc ttaaatattt
    20521 aaagaaacag tcactttatc taaacgaaaa tgaaaaaaat aaaatagata cgatactttt
    20581 caaccatcaa tataaaaaaa atattgtgat tcgaaaagca gaggctattc aatctccaat
    20641 aactttttgg tatgggaaat atattatttt gattcctagt tcatatttta aaagtgtaat
    20701 tgataaaaga ctaaaatata taatactgca tgaatatgct catgctaaaa atagagatac
    20761 tttacattta attatcttta atatcttctc tattattatg agttacaatc cattagtaca
    20821 tattgtaaaa agaaagataa ttcatgacaa tgaagtagaa gccgatagat ttgtccttaa
    20881 taatattaac aaaaatgaat ttaaaactta tgcggaatct attatggact ccgtattaaa
    20941 aaccccattt tccaacaaaa atatattaag ccattcattt aatggtaaaa aatcattact
    21001 caaaagtaga ttaattaata taaaagaagc cgatctgaaa aagcagtcaa aattaattct
    21061 aatttttatt tgtattttta ctttttttat catgataatt caaagccagt ttttaatggg
    21121 gcaatcctta actgattata attataaaaa gcccttacaa agcgattacc aaattttaga
    21181 tgaaagtaaa aattttggtt caaatagtgg atctttcgtt atgtacagca tgaagaaaga
    21241 caaatactat atttataatg aaaaagaaag tagaaaaaga tattctcctg attcaactta
    21301 caaaatttat ttagcactgt ttggacttga ccgtcatatt ataagtgata aaaattcacg
    21361 tatgtcatgg aatcataaac attatctttt cgagtcttgg aataaggaac aagatttaaa
    21421 tacagcaatg caaaattcag ttaattggta cttcgaacgt attagtaatc aaataccaaa
    21481 gaactatact gcggctcaac tcaagcaatt aaattatggt aatgaaaatt tgggaagtta
    21541 taaaagctat tggatggaag atagtttgaa aatatctaat cttgaacaag taatagtttt
    21601 taaaaatatg atggaacaaa ataaccattt tagtaaaaaa gcaaagaatc aattatcttc
    21661 ttcattattg attaagaaaa atgaaaagta tgaactgtat gggaaaacag gtacaggtat
    21721 agtaaacggg aagtataata atgggtggtt tgtaggttac gtaattacaa atcatgataa
    21781 gtattatttt gctacacatt tatcagatgg aaacccgtct gggaaaaatg ctgaattaat
    21841 aagtgaaaaa atattaaaag gaatgggtgt tttaaatgac caataagcaa gttgaaatat
    21901 ctatggctga atgggatgtt atgaatataa tatgggataa aaaatcagta tcagctaatg
    21961 aaattgtagt tgaaattcaa aaatataaag aagttagtga taaaacgatt agaacattaa
    22021 tcacaagact atataaaaaa gagattataa aacgatacaa atcagaaaat atttattttt
    22081 actcatcaaa tattaaagaa gacgatatta aaatgaaaac tgctaaaacc tttcttaata
    22141 aactgtatgg aggggatatg aaaagtttag tgctgaattt tgcgaaaaat gaagaattaa
    22201 ataacaaaga aattgaagaa ttgcgagaca ttttaaatga tattagtaaa aagtaattag
    22261 aggtatgttt caaacataat acatatgtaa accatacttg actcttatta aattagtttt
    22321 gttaatgaca tttaaaatat attattaaag atgagagtgt ccagaaaata accattttct
    22381 gtacactctt gttttttgtc taaataagta agtattacat agaattatgt gttcaaaaac
    22441 ccaacaaaaa atctatgttc acaaaagacc tcgtaatcaa gttatggtac actaaaggtg
    22501 tatataggag gtctgtattt tgaaaatagg ttatgcaaga gtttcaactg gattacaaaa
    22561 tttgaattta caggaggatc gattaaatac atatggttgt gaaaagatat ttaatgacca
    22621 tatgagtggt tcaaaaagta agcgacctgg tttagataaa gcaattgaat ttgcgaggtc
    22681 aggagatacg attgttgttt ggagattaga tagactagga cggaacatgg aggatttaat
    22741 cacgttagtt aatgaactta acgaacgagg tgtgagtttt catagtttag aagaaaatat
    22801 aacgatggat aaatcaagtt ctacaggaca attattattt catttattcg cagcatttgc
    22861 agagtttgaa cgtaatttaa ttttagagcg atcatcagcc ggtcgaattg cagcacgtgc
    22921 tagaggccga tatggaggta gacctgaaaa attaaataaa caagatttaa acttacttaa
    22981 gacactttat gataatggta cgccaattaa aacaattgca gagcagtggc aagtttcacg
    23041 tacaactatt tatcgttatc tcaataaatt agaggcaaaa gagaataaaa acaagtagag
    23101 caactaatct agcttactat aatgaatcta ctaaataatt ttatatatca ttaacataca
    23161 aagactttga ttcaatgtca ctcgatgtaa aagagacgtt ctgacagcgt ctaaaatctc
    23221 ataatatttt cctgttatga gattttaata ataacacaag aaaaaagcgt acaaattcgt
    23281 acgctttttt aatataatac ctgtttcact aatgaacgtt ttaagtatct tcatcattaa
    23341 ctgaaactac agtaataata ctcgtcaaca atattagtat agttaaaata gaaagactta
    23401 ggactggcat aaccgaacta aaattatatt tgaaatataa aagtgctaat gaagagagaa
    23461 atgtaaaaat aataaatacc aaagaccatt tttctaattt attcattggc ttcacctctt
    23521 tgaactttta tataatcata ggagatattt ttactacgat ttataaaaaa taagaagata
    23581 atcattatta aagaaacgat taatataatg ttgaatccta tagtatcacc taattcgttt
    23641 acacctttgc ctaatatcgg agatacaaag ctttgtatta ataatgaaag agatgcccat
    23701 atagtaaatg aggttctgtt gcaaagttga atttatagta taattttaac aaaaaggagt
    23761 cttctgtatg aactatttca gatataaaca atttaacaag gatgttatca ctgtagctgt
    23821 tggctactat ctaagatatg cattgagtta tcgtgatata tctgaaatat taagggaacg
    23881 tggtgtaaac gttcatcatt caacggtcta ccgttgggtt caagaatatg ccccaatttt
    23941 atatcaaatt tggaagaaaa agcataaaaa agcttattac aaatggcgta ttgatgagac
    24001 gtacatcaaa ataaaaggaa aatggagcta tttatatcgt gccattgatg cagagggaca
    24061 tacattagat atttggttgc gtaagcaacg agataatcat tcagcatatg cgtttatcaa
    24121 acgtctcatt aaacaatttg gtaaacctca aaaggtaatt acagatcagg caccttcaac
    24181 gaaggtagca atggttaaag taattaaagc ttttaaactt aaacctgact gccattgtac
    24241 atcgaaatat ctgaataacc tcattgagca agatcaccgt catattaaag taagaaagac
    24301 aaggtatcaa agtatcaata cagcaaagaa tactttaaaa ggtattgagt gtatttacgc
    24361 tctatataaa aagaaccgca ggtctcttca gatctacgga ttttcgccat gccacgaaat
    24421 tagcatcatg ctagcaagtt aagcgaacac tgacatgata aattagtggt tagctatatt
    24481 tttttacttt gcaacagaac cagcatttgt tttaatattt gttccaaaga gccatcatgg
    24541 ctttgacaga gctcttcttc tatgcaaatg cttttaatcc gatccacacg aaaattccta
    24601 tattcatttc ttagcctgca aaaccgatta agtaccagtt ctgttcataa aaccccagtg
    24661 atataggctc tatcattctg ctttccggtt cttgccctcc tgatgcagga tattgaattg
    24721 atattaccct tttattgcag attgcagtct gaattgctgc aataacgtta tccgccaatg
    24781 tatttttctg tccagatgtg ctgtacacgt taatactgtt ctccaactcc tgtgcatagt
    24841 ttttttcacc atgcttcaaa atagatttga ttttatacat agctgaatca aaatccttta
    24901 taaatgattc atctccatgg caatttaaaa atttccctgc tgtaatcaat gcacccactt
    24961 ccgccgctgt aaacattacc ggcagaagta ggaagccctc tacaagaaaa tatccttttc
    25021 cggcctcaga tccaattggt attccggctt cttcaagtgt ccggatatct ctgtaaactg
    25081 tccttaagct tatattaaat cgctgtgcaa tttctttggc aggaattatt tttttgattg
    25141 cagctgaata agaatagagg ttactctgtt aatcctgttc aaattttatt cctcctctgt
    25201 gacttccata aaaagtatat cctatgcgtt cttaagctag ctgctgttag tgcttctcat
    25261 tgcaccctgg ttataaaagc catactcaca aacctcttca ccaaaactct ttacatctct
    25321 aatatagaac tctatctagc gaacttttag aaaagatata aaacatcaga gtatggacag
    25381 ttgcggatgt acttcagaaa agattagatg tctaaaaagc ttgtagttaa agctttttag
    25441 acatctaaat ctaggtacta aaacaattca tccagtaaaa tataatattt tattttctcc
    25501 caatcaggct tgatccccag taagtcaaaa aatagctcga catactgttc ttccccgata
    25561 tcctccctga tcgaccggac gcagaaggca atgtcatacc acttgtccgc cctgccgctt
    25621 ctcccaagat caataaagcc acttactttg ccatctttca caaagatgtt gctgtctccc
    25681 aggtcgccgt gggaaaagac aagttcctct tcgggctttt ccgtctttaa aaaatcatac
    25741 agctcgcgcg gatctttaaa tggagtgtct tcttcccagt tttcgcaatc cacatcggcc
    25801 agatcgttat tcagtaagta atccaattcg gctaagcggc tgtctaagct attcgtatag
    25861 ggacaatccg atatgtcgat ggagtgaaag agcctgatgc actccgcata cagctcgata
    25921 atcttttcag ggctttgttc atcttcatac tcttccgagc aaaggacgcc atcggcctca
    25981 ctcatgagca gattgctcca gccatcatgc cgttcaaagt gcaggacctt tggaacaggc
    26041 agctttcctt ccagccatag catcatgtcc ttttcccgtt ccacatcata ggtggtccct
    26101 ttataccggc tgtccgtcat ttttaaatat aggttttcat tttctcccac cagcttatat
    26161 accttagcag gagacattcc ttccgtatct tttacgcagc ggtatttttc gatcagtttt
    26221 ttcaattccg gtgatattct cattttagcc atttattatt tccttcctct tttctacagt
    26281 atttaaagat accccaagaa gctaattata acaagacgaa ctccaattca ctgttccttg
    26341 cattctaaaa ccttaaatac cagaaaacag ctttttcaaa gttggcgtat aacatagtat
    26401 cgacggagcc gattttgaaa ccacaattat gatagaattt acaagctata aggttattgt
    26461 cctgggtttc aagcattagt ccatgcaagt ttttatgctt tgcccattct atagatatat
    26521 tgataagcgc gctgcctatg ccttgccccc tgaaatcctt acatacggcg atatcttcta
    26581 tataagcgta ccggttccaa ttttttcgca gtttaacttt tccgacgcat ttatcgtctt
    26641 ggtagtaaag atatattatc ttatcagtat tgtcaatata ttcaaggcaa tctgcctcct
    26701 catcctcttc atcctcttcg tcttggtagc tttttaaata tggcgcttca tagagtaatt
    26761 ctgtaaaggt ccaattctcg ttttcatacc tcggtataat cttacctatc acctcaaatg
    26821 gttcgctggg tttatcgata tctttcaggt gccctgcttt catttctgta atcactgttc
    26881 ccgcctctct tctatatcag cggcatatgt gctatccagg cagccggttt taccagtgta
    26941 ttttttatac atgtccctgg tatattttgt tatattccta tcatactccg gataggcata
    27001 atgaagcctt tccgccacct caccggatac cgccctgaac aattgatggc atagaaataa
    27061 tgcttcccat atgttttcat aggaatccat ccggtaggtg gacaaaagtt tctcccacaa
    27121 atcctcggat atataccttt caataaactt atagttcttg cctacacttc atttaaagcc
    27181 tgtttcgatg ccgaccttcc atgatatcat tctcagcagc tcatggcgaa caatctgatt
    27241 aaaatgatca atagcaaata aaatttcctt acggcacaat cctttaataa cataaggtgt
    27301 tacattccaa aattcattgc agcaatcatc atactccctt gcgcttggct ttcttacatg
    27361 ataatctata tcagtcggaa ctatgtccct tttaattcta caatctttat caattagaac
    27421 ctttattaat ttatcgccct ttaggtaatt atctaactct tccaagggca ataaggtaag
    27481 atcaatttta ttgtaatcat caaatagcta taatagattt agaggtaaag aaattaaata
    27541 cattgaagag cagaaagatt ttacaaaaga gtattttaat aaaaatgatg gttctgttgc
    27601 aaagtaaaaa atatagctaa tcactaatat atcatgtcag tgttcgttta acttgctagc
    27661 atgatgctaa tttcgtggca tggcgaaaat ccgtagatct gaagagacct gcggttcttt
    27721 ttatatagag cgtaaataca ctcaatacct tttaaagtat tctttgctgt attgatactt
    27781 tgataccttg tctttcttac tttaatatga cggtgatctt gctcaatgag gttattcaga
    27841 tatttcgatg tacaatggca gtcaggttta agtttaaaag ctttaattac tttaaccatt
    27901 gctaccttcg ttgaaggtgc ctgatctgta attacctttt gaggtttacc aaattgttta
    27961 atgagacgtt tgataaacgc atatgctgaa tgattatctc gttgcttacg caaccaaata
    28021 tctaatgtat gtccctctgt atcaatggca cgatataaat agctccattt tccttttatt
    28081 ttgatatacg tctcatcaat acgccatttg taataagctt ttttatgctt tttcttccaa
    28141 atttgatata aaattggggc atattcttga acccaacggt agatcgttga atgatgaacg
    28201 tttacaccac gttctcttaa tatttcagat atatcacgat agctcaatgc atatcttaga
    28261 tagtagccaa cggctacagt gataacatcc ttgttaaatt gtttatatct gaaatagttc
    28321 atacagaaga ctcctttttg ttaaaattat attataaatt caactttgca acagaacctc
    28381 ctaactgtat taccacctta aaagtagttg cagacgcact tcctaaatcg tcagcagtgt
    28441 ttaaccacat atcatcaaca ataatcatat gacctgttga tgatactgga gcaaattctg
    28501 tcaacccttc aactacacct aaaataaatg ctttaatctg ctctataaaa cccatttttc
    28561 tcctcctttt aacttatatc agttttttta aagtatgaga ataatataat tacactgaat
    28621 atagatgtaa caattatgat aattaaagat aatagaaatg gataagtatt aggtaatgtt
    28681 cctctagata tgtctccaac tgcagcccaa ggaaataatc ctctatgttc agaattagca
    28741 gtcattaaat ttatcaaagt aattattatg gttaaaacaa ttgtgggaac ataattttta
    28801 aaatatatcg acaaaataat tattggtgga gataatatcc ataataacac tccgccaata
    28861 acaaatgtaa agaatgaatc aattattaaa ctctggctta acccttgaaa atgcaatagc
    28921 atacctagca ttaaagttag caaccatgca ataacagata gtgtttgaat ccacaagaat
    28981 aataatatta ttttacttac taaaaaactt tctctagata taggtataat taataagttt
    29041 tttaaagtat cttctatata ttctcttcca aacaaatagg ctattataac cccatataga
    29101 ggaggtccaa taattagcat atgatataaa ctgacttctt caaataactg tttaaataca
    29161 atattaggag tcggtacttt cgtccgcata ctaataaaag aagctacaac caccataaaa
    29221 ggtgctacgc atgtacctaa aatacttatt agaaacatat atgatctttt taacttaata
    29281 aattctgtac ggagtagatt atccaattgt gccacctcct actaagtctt cgaaataagt
    29341 ttctagatta tcttctatca ctctcatctg gaaaacatca atattgttta atactaataa
    29401 tctattaatt tcttgttgtc tatcaatatg tgaataaatt ttaaattcgc cattttcttt
    29461 aattttatag tcataaattc cgaagttagt ttccaacaaa catgcaactt tttcttcatc
    29521 tgatactgat atacttataa attgtctgtt cttttttttt aaatcttcat acataatttc
    29581 ttctaacaaa actccgttat gaataatacc caccttgtct actaactgct ctatttctga
    29641 caatat
//
