LOCUS       NC_013303              20653 bp    DNA     circular CON 10-SEP-2023
DEFINITION  Staphylococcus aureus plasmid SAP072A, complete sequence.
ACCESSION   NC_013303
VERSION     NC_013303.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225455
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20653)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
  REMARK    Protein update by submitter
REFERENCE   2  (bases 1 to 20653)
  AUTHORS   Gill,J., Borman,J., Shetty,J., Hostetler,J., Durkin,S. and
            Montgomery,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2009) J. Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 20653)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/10/2023 04:12:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 25
            CDSs (total)                      :: 25
            Genes (coding)                    :: 21
            CDSs (with protein)               :: 21
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 3 of 4
            Pseudo Genes (incomplete)         :: 1 of 4
            Pseudo Genes (internal stop)      :: 2 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GQ900424.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20653
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="30067"
                     /db_xref="taxon:1280"
                     /plasmid="SAP072A"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2004"
                     /identified_by="Jodi Lindsay, Department of Cellular and
                     Molecular Medicine, St. George's, University of London,
                     London, UK"
                     /note="animal isolate; clinical, animal isolate"
     gene            1122..1739
                     /gene="cadD"
                     /locus_tag="HHF66_RS00005"
                     /old_locus_tag="SAP072A_002"
     ARG             1123..1736
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            1758..2105
                     /locus_tag="HHF66_RS00010"
                     /old_locus_tag="SAP072A_003"
     CDS             1758..2105
                     /locus_tag="HHF66_RS00010"
                     /old_locus_tag="SAP072A_003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            2274..2366
                     /locus_tag="HHF66_RS00015"
     CDS             2274..2366
                     /locus_tag="HHF66_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            2578..3552
                     /locus_tag="HHF66_RS00020"
                     /old_locus_tag="SAP072A_004"
     CDS             2578..3552
                     /locus_tag="HHF66_RS00020"
                     /old_locus_tag="SAP072A_004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072390.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(3672..4487)
                     /locus_tag="HHF66_RS00025"
                     /old_locus_tag="SAP072A_005"
     CDS             complement(3672..4487)
                     /locus_tag="HHF66_RS00025"
                     /old_locus_tag="SAP072A_005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(4480..5923)
                     /locus_tag="HHF66_RS00030"
                     /pseudo=""
     CDS             complement(4480..5923)
                     /locus_tag="HHF66_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(5895..6488)
                     /locus_tag="HHF66_RS00035"
                     /old_locus_tag="SAP072A_008"
     CDS             complement(5895..6488)
                     /locus_tag="HHF66_RS00035"
                     /old_locus_tag="SAP072A_008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(6752..7132)
                     /gene="blaI"
                     /locus_tag="HHF66_RS00040"
                     /old_locus_tag="SAP072A_009"
     ARG             complement(6756..7132)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(7122..8879)
                     /gene="blaR1"
                     /locus_tag="HHF66_RS00045"
                     /old_locus_tag="SAP072A_010"
     ARG             complement(7126..8879)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            8986..9831
                     /gene="blaZ"
                     /locus_tag="HHF66_RS00050"
                     /old_locus_tag="SAP072A_011"
     ARG             8987..9828
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10200..10733
                     /locus_tag="HHF66_RS00055"
                     /old_locus_tag="SAP072A_012"
     CDS             10200..10733
                     /locus_tag="HHF66_RS00055"
                     /old_locus_tag="SAP072A_012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            11147..11440
                     /locus_tag="HHF66_RS00060"
                     /old_locus_tag="SAP072A_013"
     CDS             11147..11440
                     /locus_tag="HHF66_RS00060"
                     /old_locus_tag="SAP072A_013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            11515..13449
                     /locus_tag="HHF66_RS00065"
                     /old_locus_tag="SAP072A_014"
     CDS             11515..13449
                     /locus_tag="HHF66_RS00065"
                     /old_locus_tag="SAP072A_014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            13453..13764
                     /locus_tag="HHF66_RS00070"
                     /old_locus_tag="SAP072A_015"
     CDS             13453..13764
                     /locus_tag="HHF66_RS00070"
                     /old_locus_tag="SAP072A_015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            13776..14402
                     /locus_tag="HHF66_RS00075"
                     /old_locus_tag="SAP072A_016"
     CDS             13776..14402
                     /locus_tag="HHF66_RS00075"
                     /old_locus_tag="SAP072A_016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            14640..15269
                     /gene="mobV"
                     /locus_tag="HHF66_RS00130"
                     /pseudo=""
     CDS             14640..15269
                     /gene="mobV"
                     /locus_tag="HHF66_RS00130"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            15363..15908
                     /locus_tag="HHF66_RS00090"
                     /old_locus_tag="SAP072A_019"
     CDS             15363..15908
                     /locus_tag="HHF66_RS00090"
                     /old_locus_tag="SAP072A_019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(15950..16234)
                     /locus_tag="HHF66_RS00095"
     CDS             complement(15950..16234)
                     /locus_tag="HHF66_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            16292..17152
                     /locus_tag="HHF66_RS00100"
                     /old_locus_tag="SAP072A_020"
     CDS             16292..17152
                     /locus_tag="HHF66_RS00100"
                     /old_locus_tag="SAP072A_020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            17239..17580
                     /locus_tag="HHF66_RS00105"
                     /old_locus_tag="SAP072A_021"
     CDS             17239..17580
                     /locus_tag="HHF66_RS00105"
                     /old_locus_tag="SAP072A_021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(17819..17890)
                     /locus_tag="HHF66_RS00110"
     CDS             complement(17819..17890)
                     /locus_tag="HHF66_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            18039..18224
                     /locus_tag="HHF66_RS00115"
                     /old_locus_tag="SAP072A_022"
     CDS             18039..18224
                     /locus_tag="HHF66_RS00115"
                     /old_locus_tag="SAP072A_022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(18443..19186)
                     /locus_tag="HHF66_RS00120"
                     /old_locus_tag="SAP072A_023"
     CDS             complement(18443..19186)
                     /locus_tag="HHF66_RS00120"
                     /old_locus_tag="SAP072A_023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843757.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            19597..20273
                     /locus_tag="HHF66_RS00125"
                     /pseudo=""
     CDS             19597..20273
                     /locus_tag="HHF66_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <20284..20566
                     /locus_tag="HHF66_RS00135"
                     /pseudo=""
     CDS             <20284..20566
                     /locus_tag="HHF66_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     ARG             8987..9831
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             6147..16440
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          16293..17152
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(18444..19186)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          14641..14915
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 gtgtgacact tgagcttttt atgaccccac acaaaaacat tttcgaagcc ttgaaatatc
       61 tggctttgcc agatccccca ttcattgatg gggacaaatt tcccttatgc tcttacggag
      121 attttagagt taaattaaaa tttctaagtt tttgataaga aaagccctgc aggaatttag
      181 aagaacgtgg ggaagtttta aagaatttta tgctaatttt taatttgcat gtaaatgggc
      241 agtgtctaaa aaatagttat tgtttttgct caaatttttg tttttgaaaa tagcatatat
      301 ttatttggct catatttgcg ttttaaaagc gtatataagt tttagataaa actatatgaa
      361 tcacccctaa atctttaaaa tgccctctta aaattcaaaa taagggcata aaaaataaaa
      421 gcccccccag ataaagtgag gtagcttttt ctttcgacgc cgtatcgtcg atgtaattca
      481 aaaaagttat gggctataaa tctacatcac tttttcaaga atgtagtagc aatattcaac
      541 gcaaattaat ttttataact gctcggaata tctcaagccg tttctttaat tttgaaataa
      601 aaaaatcgac gaaggtcgat tacgtttttg cacatgtcga tttatccgac gtataagtgc
      661 gcccttacgg gatttaacta gattataacg acgaatttta gacctgtaaa gcaataacaa
      721 ttaggtctac caggtagata aagtgtacaa agtagaaccg aaaaagttat ttattttgaa
      781 gatttttcgt agatataatt tgctaataaa cttcctaaaa ctgaataaag aaaaatagtt
      841 aaactcatgt aatcactcca taattctgaa gtgtctccat gtctacgcat agacacgcat
      901 ttatgccgag aaaatttatt gtgcgttgag aagaaccctt aactaaactt gcagacgaat
      961 gtcggcatag cgtgagctat taagccgacc attcgacaag ttttgggatt gttaagggtt
     1021 ccgaggctca acgtcaataa agcaattgga ataaagcacc tatgattatt taaaaatata
     1081 agttataata cattcaaaaa tatttttgaa tgaggtgtat tatgattcaa acggttgttg
     1141 ctgctgctgt tctttatatt gctacagcag ttgatttatt agtaatttta ttaatatttt
     1201 ttgctagagc aaagactaga aaagaatata gaaatattta tgttggtcaa tatttagggt
     1261 ctattatttt aatattagtt agtttgtttt tagcttttgt attaaattat gttccagaaa
     1321 agtggatatt aggtttattg ggtttaatac caatttatct tggaattaaa gtggctattt
     1381 atgatgattg tgaaggagaa aagagagcta aaaaagaatt gaatgaaaaa ggattgtcta
     1441 aattagttgg tacggttgca attgttacga tagcaagttg tggcgccgat aatattggtt
     1501 tatttgttcc ttattttgtg acattaagtg ttactaattt attacttact ctgtttgtct
     1561 ttttaatttt aattttcttc ttggtgttta ctgcacaaaa attagctaat atcccaggaa
     1621 ttggagaaat tgttgagaaa tttagtcgtt ggattatggc tatcatttat atagctttag
     1681 gtttatttat tattattgaa aatgacacta ttcaaacaat tttaggattt atattttaat
     1741 ttagggtgtg attttatatg agttatgaaa atacttgtga tgtgatctgt gtacatgagg
     1801 ataaagttaa caatgcttta agttttttag aagatgataa atctaagaaa ttacttaaca
     1861 ttttagaaaa aatttgtgat gagaagaaat tgaaaatcat attatctttg attaaagaag
     1921 atgagttgtg tgtttgtgat atttctttga tattgaaaat gagtgttgct tcaacttcac
     1981 atcatttaag gcttttatat aaaaatgagg tacttgattt ttataaagat ggaaagatgg
     2041 catattattt tattaaagac gatgaaataa gagagttttt ctctaaaaat caggagggtt
     2101 tttgaaacga gtgaaacgag tttcttcttg tcttgatact ataaaaaaca aagttatata
     2161 acataagacg acttatcgga agttatctat catcgtatat tcggagatga tataatatac
     2221 aggtcgccta tctctcaggc gtcaattcag acgcagagag gaggtgcatt actttgctaa
     2281 tcattttcgt tcacatcata gcaccagtca tcagtggctg tgctgttgcg tattatactt
     2341 attggcttag taaacgcaac aaataattaa taggcgactt tataagccag catcgaaaaa
     2401 atccccacac tattgcagta gtgtggggat tggtgcatta attgttaatc attttcgtta
     2461 tctagattat aacactggtt agtagaggaa tgcaaaaaga taatatttta agtagtcttt
     2521 ttggatatta tcatatgata tatttatgta aattgatttt ttattaaagg agcatatatg
     2581 agtaatacta aaattaaata tcaaattttt atttcatcaa cttatttaga tttaatagaa
     2641 gagcgtcaag cagtagtaga agcagtttta aacagtaata atattccagc aggtatggaa
     2701 ctttttaact caagtagtaa aagccaatgg gaaataataa cacaatggat caatgaatca
     2761 gatgcagtga tattattgtt aggttctagt tatggaacaa ttgatagtga agaaaatatt
     2821 agctatacag aaatggagta caattttgct aaatctttag gtaaacctat atatgttttt
     2881 gagatgaata aagcatctac cgaatccgcg gaaaagtcta aaaaattaga tgagtttaag
     2941 acaaaagtta aagaaaatag actaattagt ccaaatatta atgatatttc ggaattaaaa
     3001 agtaaagtat ctcagacttt aatgcaaagt gtacctagtg aaattaaaga aaatagtgga
     3061 tggataagag tacaggattg tggtaaaaat gtaaaaaaat taaaaaaatt ggatgctata
     3121 caaagagatt tagatacata tgattttttg aaagaagaac tttataaaat attcatgtat
     3181 gtaaaaactt tttatttcca gcacacacca tttgatgata gttatattga agatatagaa
     3241 aactacctgc taaattatga aaataatcca cataaatcat tcatgaaaat aaaagtttat
     3301 gattataaaa actttttaaa acatttaaaa aacatattga ttttaattaa acaaggaaaa
     3361 aagccattag ctcaagccgg tcattttaaa ttaagctttt acgaagagga tttaaaattg
     3421 ttacaaaaaa attataaggc tacgctagtc gatattaaag gattgaataa acatttttat
     3481 aaggaatgtg ataggtgctt aaaagcatat aatattttta ttgagggtat aaataaacat
     3541 ttatatgaat gatataagta caccctaatc atacatatat aattgttgtc actttactcg
     3601 atatatgaga atgactttac ctaataaatg agaaaagcaa cgcactatat taaaatgcgt
     3661 tgctttttct attatcgaat acctataact aaactatctc tagctgtttc tacaacttct
     3721 gtacttattt tatctaaacc atttatatcc ataattctgt ctatctgcgc aaataaacga
     3781 tgaatcagcc taaaattccc ttttgtaatt ttaataatcg tcgttattgc ctcataatca
     3841 gtaaagtctt cgagttttaa atcaaatcct aagtcttgcc acttatattc taatatatga
     3901 tgcgtctcat ctttacttag attatcaaat tcatgcgcaa aacctatacg cgaatatagt
     3961 tgaggataac gagatagttt tttctctata cccggcatac caataaatat cattgctaaa
     4021 ttatgttcat cataaatagc tcttaattgc tctaaatgtt gcactttaag gcgatcaatc
     4081 tcatctacta taattaaatc aatatattta aacatatcac tataatgttt actatgttca
     4141 tgtccatact tatttacaac atgtaatttt tgacccaaat caatgattgc agtaatacta
     4201 tataaatcat tccttaattt agtttgtttt tctgctggtg cattataaaa tattttatcc
     4261 accgatagta tgtcatcggt cgttttacta gctaaatctt cccaacctct atggttaact
     4321 tgtttttcaa tagtatccca atttgtgtaa tacctagacg ataaagtttt tccgacacca
     4381 ggttgaccat aacatatacc aatatactga tatttaatac aagcatcaca aaattcagca
     4441 aagcgtttat actctttcgt ttcaatgaaa ttttgatttt tagtcattac gatatctctt
     4501 taattttttg acgtttttag tcgtttcttg aggtgaataa ccacaatttt tttcttcctt
     4561 aattaattcc gtggtacttg gactagcaat attttgtttt aagtgttttc ttctctgact
     4621 acgagcgtgc tgtatgtctt ttatatctat ggagtaatca gctatttctg gacatatagc
     4681 agtacaaaga aattcatctc tataaaacac acgtatttca gccatatcat ttgggttata
     4741 acgaatcagt acatattcac ctacataagc ttctagatta gtattactgt atcgaaaacc
     4801 ttgaaaatga atgccatctg aatgaacttt tctagattta ggtatttcca acaataataa
     4861 atcaagttgt tctaagctac ttggcatatt agggaaaaag tgattactat tccaatgact
     4921 gataggcgtg gtatgaatag tactatgttc tttttgatta taatcttcaa ttaaaaagta
     4981 acgtaatttt tcttcaaaat tgtgaaaatt tattagatta ctaggagtat cattattgtt
     5041 tatatatcca ggcagttgtt ctaagaaagt ttgattaact gtctgaaaga atcgttctat
     5101 ttttccacga ccacgaggaa caccaacttt cgaaaacatc aagttaattt tcaaatcaat
     5161 agcgacttgt tccatatgat gtgaagtaaa gtcacttcca tgatctgtgt agaatttttc
     5221 gggtatacca cacactggcc aattggtatc atttttattc catattgctt ggtgtagtgt
     5281 taatgctgtg ttttgagcat tggggggcat caaaacttaa gaaatagcct gcaattgcac
     5341 gactatagtc atccataata atagttagcc atggtctatt gatattacct ttttggtcta
     5401 atataaagat atctagcaaa gtatggtctg cttgccatat ttcattgggt ctcgaggatt
     5461 ctctaatttg tattaaatcg tacttatttt gatagtattt ttcaccctga tgagagaaat
     5521 caataacaga cttaggcatc gctttaataa cactataaat ttgtttataa cttggtatat
     5581 caaaattatt ttctttacag taattagtga ttttcctatg aattgtggct atactatttc
     5641 ttttattcat aagcgcaagg cgttcaattt catcaattat ctttggttct attttacgtg
     5701 ttcctttatc agctcttgtc gcatagatta gtcctttaag tccttgttct ttatatgact
     5761 tattccacct ataaagggtg cttaacgcaa tccctttact tttagaaata cttgataaag
     5821 attgttcgcc taggataaaa ggttttataa tattgtactt ttgagtagct tttttacgtt
     5881 tggcttcaga aaaattagtt agatacttct ccttgttttt catcttcctt gtcctccaat
     5941 ttattgaggt aacgataaat tgttgtacgt gaaacatgcc actgttctgc aattgtctta
     6001 attggcgtgc cattatcata aagggtctta agtaagttta aatctttttg atttaatttt
     6061 tctggtctgc ctccatatcg gcctctagca cgtgctgcaa ttcggccagc tgaagaacgc
     6121 tctaaaatta aattacgttc aaattctgca aatgctgcga ataaatgaaa taataattgt
     6181 ccagttgaac ttgatttatc cattgttata ttttcttcta aactatggaa acttacacct
     6241 cgttcgttaa gctcattaac taatgtgatt aaatcctcca tattacgtcc caatctatct
     6301 aatctccaaa caacaatcgt atctcctgac ctcgcaaatt caattgcttt atctaaacca
     6361 ggtcttttac tttttgaacc actcatatgg tcattaaata tcttttcaca accatatgta
     6421 tttaatcgat cctcctgtaa atttaaattt tgtaatccag ttgaaactct tgcataacct
     6481 attttcaaaa tacaaacctc ctatatacat cttcagtgta ccataactta attacaaggt
     6541 cttttatgaa catagatttt ttgttgggtt tttgaacaca taatcctatg taattcttac
     6601 ttatttagac ataaaagaag agtgtacaga aaatggttat tttctgtaca ctctcatctt
     6661 taataatata ttttaaatgt cattaacaaa actaatttaa taagagtcaa gcatagttta
     6721 catatgtatt atgtttgaaa catacctcta attacttttt actaatatca tttaaaatat
     6781 ctcgcaattc ttcaatttct ttgttattta attcttcatt tttcgcaaaa ttcaacacta
     6841 aacttttcat atcccctcca tacagtttat taagaaaggt tttagcagtt ttcattttaa
     6901 tatcgtcttc tttaatattt gatgagtaaa aataaatatt ttctgatttg tatcgtttta
     6961 taatctcttt tttatatagt cttgtgatta atgttctaat cgttttatca ctaacttctt
     7021 tatatttttg aatttcaact acaatttcat tagctgatac tgatttttta tcccatatta
     7081 tattcataac atcccattca gccatagata tttcaacttg cttattggcc atttaaaaca
     7141 cccattcctt ttaatatttt ttcacttatt aattcagcat ttttcccaga cgggtttcca
     7201 tctgataaat gtgtagcaaa ataatactta tcatgatttg taattacgta acctacaaac
     7261 cacccattat tatacttccc gtttactata cctgtacctg ttttcccata cagttcatac
     7321 ttttcatttt tcttaatcaa taatgaagaa gataattgat tctttgcttt tttactaaaa
     7381 tggttatttt gttccatcat atttttaaaa actattactt gttcaagatt agatattttc
     7441 aaactatctt ccatccaata gcttttataa cttcccaaat tttcattacc ataatttaat
     7501 tgcttgagtt gagccgcagt atagttcttt ggtatttgat tactaatacg ttcgaagtac
     7561 caattaactg aattttgcat tgctgtattt aaatcttgtt ccttattcca agactcgaaa
     7621 agataatgtt tatgattcca tgacatacgt gaatttttat cacttataat atgacggtca
     7681 agtccaaaca gtgctaaata aattttgtaa gttgaatcag gagaatatct ttttctactt
     7741 tctttttcat tataaatata gtatttgtct ttcttcatgc tgtacataac gaaagatcca
     7801 ctatttgaac caaaattttt actttcatct aaaatttggt aatcgctttg taagggcttt
     7861 ttataattat aatcagttaa ggattgcccc attaaaaact ggctttgaat tatcatgata
     7921 aaaaaagtaa aaatacaaat aaaaattaga attaattttg actgcttttt cagatcggct
     7981 tcttttatat taattaatct atttttgagt aatgattttt taccattaaa tgaatggctt
     8041 aatatatttt tgttgaaaaa tgaggttttt aatacggagt ccataataga ttccgcataa
     8101 gttttaaatt catttttgtt aatattatta aggacaaatc tatcggcttc tacttcattg
     8161 tcatgaatta tctttctttt tacaatatgt actaatggat tgtaactcat aataatagag
     8221 aagatattaa agataattaa atgtaaagta tctctatttt tagcatgagc atattcatgc
     8281 agtattatat attttagtct tttatcaatt acacttttaa aatatgaact aggaatcaaa
     8341 ataatatatt tcccatacca aaaagttatt ggagattgaa tagcctctgc ttttcgaatc
     8401 acaatatttt ttttatattg atggttgaaa agtatcgtat ctattttatt tttttcattt
     8461 tcgtttagat aaagtgactg tttctttaaa tatttaagat ataataaggc tttcaaaaat
     8521 ttaaaactta aaataataac taaaactatc caaataactg tgcagatatt atcaattgaa
     8581 tcccaattaa acttatggat atctgttgcg aactcttgaa caggtttggt ggtaattatg
     8641 ttatggttca agtcgtgtga cttactttca actgtgggcg cttgattatt cacattatta
     8701 aattttataa aagagaattt aattgggata aaaggaatta atccagcaag cacagttaga
     8761 taccaaactt tataatttaa actataatta aaatagcgtt ttaatatgta cctaaaaaat
     8821 actaacaata gaaatataaa acaaaagctt actacactca ttattagtaa tttagccatt
     8881 ttgacacctt ctttcaaata tttataataa acaattgaca tcaatattac aattgtaata
     8941 ttattgtttt gtaaaaatta caactgtaat atcggagggt ttattttgaa aaagttaata
     9001 tttttaattg taatggcttt agttttaagt gcatgtaatt caaacagttc acatgccaaa
     9061 gagttaaatg atttagaaaa aaaatataat gctcatattg gtgtttatgc tttagatact
     9121 aaaagtggta aggaagtaaa atttaattca gataagagat ttgcctatgc ttcgacttca
     9181 aaagcgataa atagtgctat tttgttagaa caagtacctt ataataagtt aaataaaaaa
     9241 gtacatatta acaaagatga tatagttgct tattctccta ttttagaaaa atatgtagga
     9301 aaagacatca ctttaaaaga acttattgag gcttcaatga catatagtga taatacagca
     9361 aacaataaaa ttataaaaga aatcggtgga atcaaaaaag ttaaacaacg tctaaaagaa
     9421 ctaggagata aagtaacaaa tccagttaga tatgagatag aattaaatta ctattcgcca
     9481 aagagcaaaa aagatacttc aacgcctgct gctttcggca agactttaaa taaacttatc
     9541 gcaaatggaa aattaagcaa aaaaaataaa aatttcttac ttgatttaat gtttaataat
     9601 aaaaacggag acactttaat taaagatggt gttccaaaag actataaggt tgctgataaa
     9661 agtggtcaag caataacata tgcttctaga aatgatgttg cttttgttta tcctaagggc
     9721 caatctgaac ctattgtttt agtcattttt acgaataaag acaataaaag tgataagcca
     9781 aatgataagt tgataagtga aaccgccaag agtgtaatga aggaatttta atattctaaa
     9841 tgcataataa atactgataa catcttatag tttgtattat attttctatt atcgttgaca
     9901 tgtataattt tgatatcaaa acctgatttt ccctttatta ttttcgagat ttattttctt
     9961 aattctcttt aacaaactag aaatattgta tatacaaaaa atcataaata atagatgaat
    10021 agtttaatta taggtgttca tcaatcgaaa aagcaacgta tcttatttaa agtgcgttgc
    10081 ttttttctca tttataaggt taaataattc tcatatatca agcaaagtga cataattgtt
    10141 gaatttatag taactgaaac gtatgattag ggtgtatatt aattatgaga tggaaatcaa
    10201 tgattgttgg ctatgcgaga gtatcatcga acgatcaaaa tttagaaaga caacttgaaa
    10261 atttaaagac gttttgtgct gaaaaaatat ttacagaaaa acagtctggg aaatctattg
    10321 aaaatagacc agtacttcaa gaagcactta actttttgag gatgggagat cggtttgtag
    10381 tagaatccat tgattgttta ggtcgtaatt atgatgaagt ggttggcaat ccattactgg
    10441 ataagtttat gaaagattta attattcaaa tattagcaat ggtttcagaa caagagagaa
    10501 atgaaagtaa acgtcgacaa gcgcaaggaa ttcaagttgc gaaggaaaaa ggcgtatata
    10561 aagggcgccc cttactttat tcaccaaatg ctaaagatcc acagaaacgt attatttatc
    10621 atcgcgttgt agaaatgtta gaagaaggcc aatcaattag taaaattgcg aaagaagtaa
    10681 atataacaag gcagacgatt tacagaatta aaaacgataa tgatttgatt taataaactt
    10741 tgtttcaatg caactgagag cttctcacag cgtctcaaaa cagatgatta taatctatta
    10801 tgagttttta ataataagac aagaaaagag agcgtaaata tgctctctct ttttctcatt
    10861 aacgaacgtt tataacgcaa tcatgatgag agtattaata cagttaatta tttgaaatac
    10921 tttagtttat ataatgttga attataggta gtgaaattgt atttattata cattgtcata
    10981 tcgttgttta atgatagtta atttaaggat aatagaatta atattatata tagatgaaca
    11041 aaacaagcaa cagagcagaa aaaacacttt tagattattt ttactcattc tctattttat
    11101 ttatttttgc tataataaat aaagaatatt aaatggaggt gtttttatga aaaagaaatt
    11161 tgtttctagt tgtattgcta gtacaatctt attcggcact ttattaggtg taacttataa
    11221 agctgaagct gcaacagtac atgtagctgg tggtgtttgg agccatggta ttggaaaaca
    11281 ttacgtatgg tcttattata gtcacaataa aagaaatcat ggttcaacag cagtagggaa
    11341 atattcatct tttagtggtg ttgctcgacc tggtgttcaa tctaaggcat ctgctccaaa
    11401 ggcttggggt ggaaacaaaa cattttatag tcttcactaa ttacatatat taattaagga
    11461 gaatagacag aattaagtaa acttaattct gtctattctc ttgaaagagg caatatgaaa
    11521 aaattcaaat tatttttaga ttttagtact ttattattaa tttcagggct attattttta
    11581 tttttcttca aagaaaatga agaaattata cctgaaagtt ccaatatttt aacaatctct
    11641 aattgggata aatctaacag taaatcaaaa gtgttagatg tcattgaatc aggcgccaaa
    11701 aatcaaaata tacaaataat taaatccgtt aaagattttg ataataaaaa agaatttttt
    11761 gttttcaact caaaacgaaa taattctgac tttatacgta ataaaacatc acttttaact
    11821 ccatcagatt tattaaacag agagataaaa ggaaagtatt atattattgg tgaacatttc
    11881 aatgtagaag agcttacgag tgaattaaaa aaagctggtt taacatctga agttgaatac
    11941 ataaatagaa acatattatt ttttgaatta gtcatagata atgatttatt agtgcctttc
    12001 atattcttag gcgtattata tcttttgtac ttcttatatg acagaggata taatttgaaa
    12061 ttttatgcta ttcaaaagct acatggcttt tcaactacac gcattatttt tcataatatt
    12121 catataaaaa tcatttattg gctagtactt accgctattt tctttattgc taatatatta
    12181 atcattcata tagccaattt agaattggat ttcttaatgt ttattcgtag atttatcgtg
    12241 ttgctttttg tttttgcttg tattactaca ttgctgtggc tgatttcgta tagtcttctt
    12301 ttgaagttaa gtattccatt aatcttaaaa gggaaaaaag gatataagtt ttcaatattt
    12361 atgggtacct tcaccaaatg tatcatggtg ctaatactat cttttttact ggcacaaaat
    12421 ttaaatgctt atacgaagtt aaagaatata tatgactctg aaaaaatctg gcaaaagtta
    12481 gataattact atacattaga gatttctcct aatattagaa attcagaaga aaaacaaatt
    12541 ttagaaacta atatatacaa tttaattaag aaaagcgaac aacttggtgg attgctttta
    12601 aagaataata atatagccaa tcccgataaa aacaattaca ttcctgaaaa tggcaatgtc
    12661 ttttttatca ataacaattt tctgaatttc tataaaaata taaatcatga ttttaaaatg
    12721 attgacaatc attcggataa aataaacgtg tttattcctc caaggttaca atatcaaaaa
    12781 tctgaaattc aaaaaaatca ccaaggatgg attgactttc aaaagcaaca aaacaaaaaa
    12841 gtagatgtgc aagtactgtc aaaaaacgta tctgtttttt cttttgatcg cacaactaat
    12901 ttgaaatttg ggtatctaga ttctccaata gtaatgttgt tgacacttga cgatttaaca
    12961 ggagattttt atttagctgc tgtttctcaa ggtggatatc tatttaaaga tttagataca
    13021 cttaaacagt tgcttaaaga taatcaccta gaagaagaaa ttagcggtat aactaattac
    13081 aaggattctg tgttaaatga attaaatgaa acgaaaacaa aaatgataat aacaatagtt
    13141 actattatta ttaacgtttt cattcttttg atagctactg tatttgaaac aattcaatat
    13201 tttagctgga ataaaaagca actattatta agaaaaattc atggttattc attattcagc
    13261 agtaatgtac gttatttaac aatttctatc ttactttcta ttatgttagc ttacactacg
    13321 catattttat ttggttcaaa gatattacta ttcataataa tgtctattgc tattattcaa
    13381 catttacttc aaattgctta tattaaatat cttgaaaaat actttaaaga tttaatgagg
    13441 gagatttaaa caatgaaaag aactttaatt attgtaacaa ttgtactatt aatcatcata
    13501 cttagtctgt tattggttag aaatgagcat ttagatcgtt ttaacccact gttaaaagaa
    13561 aaagtatctt atgccaaagt tccaaaagat acccaggact atagaaatat aactgtatac
    13621 tctaaaaatg gagaaaaaaa gagttataaa ttggattttt taggttatga tcctacaaaa
    13681 gaatatgtga aagtaaatca taaagggaaa tatgtgcgtt cgatagaata cattacaaaa
    13741 gatattccta gctttttaaa atgaggtgac cgatagtgat aaaacttgaa aatgtttttg
    13801 taaaaaaagg taataaaaac attttagacg gatgtaactt taattttgaa aaaggaaaat
    13861 catatgcttt agttggagaa agtggcgctg gaaaatctac tttacttaac ataatcgctg
    13921 ggttcgaaga tgtatcacaa ggaagcatat atattgaaga taagttacta aaaaagaaag
    13981 tcgattttta tagatatacg ttagggtatt tgtttcaaaa ttttgcttta cttgaaaatc
    14041 aaacaatcag tcaaaattta gatttagccc taaagttcaa aaagaataaa aaagataata
    14101 tgaacttaaa gaaagaagta ttaaaaaagg tcggcctaga tttagatatc aagagaattg
    14161 ttagttctct aagcggtggt gaacaacaaa gagtagcatt ggcaagatta atattaaaag
    14221 atccgaaaat cattttagct gatgaaccta ctgggtcact agatacgaaa aatggaaaaa
    14281 tagttattga tttattattg aagctacttg atgaaaataa aactatgatt gtcgtaacgc
    14341 atgatttaga gcttgcgaaa cgatttgatg tcatagtcaa tatttctgag cttagaagtt
    14401 aagaaatatt gataggtata gccatacata gagaaaaaac aatatgaaat atgattagtc
    14461 attacttttg agttttttaa tttaaggact ggattttcca gtcctttttt atgatgacaa
    14521 aaaacaagcc tcgcagagca cacgttttta atgacttatt tggtttttaa taagtctagt
    14581 atgttaaaac ttttctgtgt ttaggtgtta taatcatatg cagtggaagt tgatttatta
    14641 tgtcttattc aattattcga gttgttaaag tgaaatcaaa aacaaataca agaggtattc
    14701 aaagacatat tcaaagagaa aataaaaatt atgaaaatat agatattgat ttaagtaagt
    14761 catatttaaa ctatgattta gtcaatgata ctaagtttga ttttaataaa aaaattgatg
    14821 agaaaatcga aaaaaattat aaagggaaac gcaaaattag aacagatgcc attaaacata
    14881 ttgatggatt aattacatca gataatgtgt tttttaatca attatctgaa gaagagacaa
    14941 aatagttttt taagcatgct aaagcgttct tggaagaaga atacggtaaa gaaaatcttt
    15001 tatatgcgac agtacatatg gatgagataa caccacatat gcattatggc gtagttccta
    15061 ttactaaaga tggacgttta agtgcgaaag aagttgtagg taataaaaaa gcattaaccg
    15121 aattccaaga tagattcaat acgtatatta ataagcaagg ctatgattta aaacgaggaa
    15181 tttctagaca acttacaaaa gaaaaacatg atcaagttag ccgttataaa caaaaaacag
    15241 aatatcataa acaaatgcat atgcgctaga agcaaataga ggattattta aagcaagaaa
    15301 atgataaatt gatacaaaac taccaaaaat cattagatac gcttaaaaag cttctgagtg
    15361 tcatgtatga aattaaaact aaaaatgtag gtggatggtt tcataaagag aagcaagaaa
    15421 caggcaatat tgtaattact aaaactgatt ttgaaaaata cactaaacaa attaaagcag
    15481 cacagatgat attagatgat tatgaatgta ttaaaagtgg gaagtcatta aaaaaagcag
    15541 agaaacaaaa tgaaagttta gttaatgaat tgactagtgt ccatatggaa aatgaaaagc
    15601 tggttgaaga atttaatgat ttagcacaac gttataatta tttgttgtca gagaatgaaa
    15661 agaaagataa agaactaaat tatacgctta agttattcaa tcaagttttt aaaatcatta
    15721 aaagtatgat gaaagaagag cgttatcata cactaataaa tcatattgat aatcatttag
    15781 acaattctaa aatacgtgaa gtaatgacga tagataacaa tgatgaacag ttctttaaga
    15841 agaaatatca agcacaagaa cgagaaatca tttttaaaga agatagagaa gatggttata
    15901 cattataaaa atagatattt aaatgcattt gtttgaggtt aattattttt taggatgaaa
    15961 aataggtagc ccccctcgaa ctttttaata tatttttata aatcttttta aaaacctttt
    16021 taggggcttg ttcagcccta gagcaacaag ggatttcaat gcctaaagga gtgtttttgc
    16081 cacataaaag gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt
    16141 ttttgccaca taaaaggagt gttttaaaaa gttgtactcc ttttatggtt tgacattgat
    16201 aataaagtag tttattgtga ataaaagttt tcaaatggga gtgtatattc aaacgatact
    16261 cctttaggtt cgtaataaag ggggctgtat catgacagga gagacagttg tatataaaaa
    16321 tgaaatgaat ttagttccat taaggcgatt tacagctact gaaattaatt tattttttgc
    16381 gatgtgtaat aaattaaaag agcaagatac taatacatta cgtttgtctt ttgatgaatt
    16441 aaaaaaatta agtaattata gtccagaaac acgtaatatt aatagatttg ctaatgattt
    16501 agataatgtg tataaaaaga tgttgaattt aaccattaga tatgaagatg atgatgtaat
    16561 agaaagattc gttttattca atcattatag aatccataag cgagaacaat atctagaaat
    16621 atcaacttct tcaaatttaa aacacatatt gaattcaatt actaataatt ttacaaaatt
    16681 tgaattaaaa gaaatgacta ggcttaaatc tacatattct aaaaatatgt ttagattact
    16741 taaacaatac aaacatacag gctatttaaa aattcacatc gatgatttta aaaatcgttt
    16801 agatatacct aaatcttatc gtatgactga tattaacaaa aatgttttta aacctattat
    16861 tattgaatta ggttctatat ttaataatct tactatcaat aaaatcaaag cgaaaaaagg
    16921 gcgtaaaatt gaatggatag agttcacatt tgacgctgag aaacgcattc ataacaaacg
    16981 acaacctcaa atgtccaaga tagataaatc aagacaatat gtgaggcgtg aaaagacgcc
    17041 taaatggtta gaagaacggt catatgaaaa gcaacctcaa aaagattacg acccacaatt
    17101 agagaaagaa cgagaggatt ttttaaaaca acttgaactg aattgggaat aacgcaactt
    17161 ttcgttgcga gttggttaac taaaagtatc gtgacttttc aattatttta attatagttt
    17221 gagttaagga gtgattttat gaaattagct gaagctataa aagaacagag agaattaaaa
    17281 ggatggtctc aagaggaatt agccaatata ttaaaggttt ccagacaaag tgtttctaaa
    17341 tgggaaagtg ccaaaaacta tccttcctta gatattttga ttgctatgag cgatttattc
    17401 ggaatctctt tagagcattt aattaaagga gatgcacgtt ttaaaaaagt tattttagag
    17461 ggaaattata gagagagtaa cagggtacct tccatagttg attttcttta tgatttttgg
    17521 tggcttttct ttcctgttgc cggattttta gtttgggcca ttcattcgtt catgggttga
    17581 ttttaaaatc aaaatttaat gcacatcagg caatatgaaa aaggaaagta tttttacgac
    17641 accttgaaat gtattgataa gaatagaaga gtttacaaaa ggcaatatga aatatatact
    17701 aaaagtaaca agaatttcgt ttgtaaacgc accaaacccc gaactattcg ccgtagttcg
    17761 gggttttttg gtgaattggc tttaatcgtc tatattattt tttatcacgt ttatggagct
    17821 aataaccaaa taacgtaacg agacaaccac tgattgccgt tgtcatgatg tgaacaagaa
    17881 tttcattcat aaatcgcacc tcctctctac gccgaattga catctgagag atagacgacc
    17941 ttcacattat aacaaatctc tccttccatg aaataacatg aatattaata aatgttgtta
    18001 tatattaaag ataaataaat ataagggtgg gattgataat gtttggcgat caaagacaag
    18061 aagctacaaa atatgtcatt aaagaaggtt atcaagatat ttatttcctc aacaaaaacg
    18121 gggaatggta ttatttcgaa gtaagaagtg tctggcgtgg caaacatatt attagagtta
    18181 aagatggttt gttaggttgg agaaaagaaa tagtaactga ataaagatac aaaatacttg
    18241 ccaatgcaaa agaatgaaaa cgcgtcaaat caacgatgta taaaagatgc ataaaagata
    18301 atgaaagtaa aaagccataa atgccgtcat ataggcattt atggcttttt gtttggttaa
    18361 tataatcgat gattatcaga agttcaattc acataaaaaa gcacggctaa tttatgaact
    18421 tgtcgtacct ttttaattaa aattagttac caaatagacg actccaaaac ccctttttag
    18481 cttccgtttc ttcactcttt tcttctatat cactatcatt gtcatttgga ttagctgaaa
    18541 cgtcttctct ttgtgcttct tcaccttgtg tactttcgtc gctttgactt ccagatatat
    18601 ccttatattg aatctctgtt tctttagttt cttcctgatc tcggttaata tttacaggac
    18661 tagtagtata tgttttttct tgtgcatcaa cgttttgtct agcgttagta gatgtatcaa
    18721 agggataatt aaggtgtttt tctttttcta attgattttc taatttttga atctttttat
    18781 tactctctaa tgccagaact tgctgattct caagcaattt tgatctttct tgcaactctt
    18841 ttctgtaaaa ttcaattgtt gtttcatgac gactttcttg tttttcaatt tgattattta
    18901 aagtattaat ctgattttta agtatttcta ctatttgagc atcgctttta gattcaaaat
    18961 taatattatc cgactctttt ttttgtttgt cttcagtagc actttcaaaa ccatatttct
    19021 ttttattttc atttactctt tgaatgattt tttctatatc ggtatcttct ttaataaacg
    19081 aagtgttttc ctgttttatt gtctctatat tcaatctctt aatattatta aaaatcgttt
    19141 gcttactaac ccctaattct tcactcaacc tttttacact tttcatatca tcaacccttt
    19201 ataaaatgtt tataaaccct tagtaaaata ttataagctt ataacgatta ataataaagt
    19261 aatcgacaaa taaaaatata aattcgccaa cctttttatc aagggtttgt aaagggttta
    19321 tggtgtttat caaaggttta taaacctata ttttcccttt tttaagttta ttcaaagtgc
    19381 tataataacc ttaatataac aaaaacccca actactggta atagtcgggg tttggtaata
    19441 aaacgtttag aaactgttta tttatataat tttcgatact tagattatat aatgaataat
    19501 atcttagtgc aagcacctag attattaaat aaacacaaaa aatgtaagcg ttttattacc
    19561 tcttaccaaa ctaaaattcg gaaagaggtt tttattatgt caattaaact ttacaacata
    19621 aatgaggaat acagagaaaa gttttatcaa ataccgaaag tattttttac aaatcctaaa
    19681 tatatcaagt tatccaatga tgcaaaaatg gcatggggta ttcttagaga tcgtttagat
    19741 ttatcaatta aaaatggttg ggttgattct aaaacaggta atatttattt ttattacaaa
    19801 aatgaaaacc cacaaaatat attaaattgt aaaaaagata aagtaattaa aataaagaaa
    19861 gaacttaatt gaagccgaat tactactaca agaaagacaa ggtttaaata agacaaataa
    19921 actttattta gttaaaccag aagtaacaga agatgatatt tataaaattc aaaagcaaga
    19981 aaacactgtt gagagcagca atggcaagga agtcggaaaa accgacttca agaagtcgat
    20041 aaaacagaat ctaatgatac tgaacttagc tatactgaat ctaacaatac tgaaataaat
    20101 gatatgaatg acttgaatga tatagagtcc gaaaatgaaa ttagtaatca ttcaagtcaa
    20161 tgcaaggtta tttaatgcaa acaattttaa ctgaatttga agaaacacat gcactttata
    20221 tgcgccgtaa aaacatgaaa caatataata tctttaatca atcattcaaa tgattttata
    20281 acaatcaaag atacatcaaa atatttcgtt aaatcatctg actttttaac tgatagcgat
    20341 gaaaaaatca agaaattgtc agtgatctag aaaaagattt gtatcgaaaa cgtatgttaa
    20401 gttatggtgg attgcttaaa taaaaacata aaattttaaa cttagacgat gctgaagatg
    20461 gcaatttaat taatacaagt gatgaagata aaatagcaaa tgaagaagaa aaggcacatt
    20521 cgattacggc aattttgaaa agcaaaatta ttatttaagg cattagtgat aactgatgtc
    20581 tttttttatt acttttttgt aaaaaaagtg ctgtcttatt tttgtgacaa atgctgtatg
    20641 tagtgtcaca aaa
//
