LOCUS       NC_013298              27067 bp    DNA     circular CON 10-SEP-2023
DEFINITION  Staphylococcus aureus plasmid SAP050A, complete sequence.
ACCESSION   NC_013298
VERSION     NC_013298.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225408
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27067)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
  REMARK    Protein update by submitter
REFERENCE   2  (bases 1 to 27067)
  AUTHORS   Gill,J., Borman,J., Shetty,J., Hostetler,J., Durkin,S. and
            Montgomery,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2009) J. Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 27067)
  AUTHORS   Summers,A.O., Shearer,J. and Wireman,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2009) Department of Microbiology, University of
            Georgia, 527 Biological Sciences Building, Athens, GA 30602, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/10/2023 04:08:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 32
            CDSs (total)                      :: 32
            Genes (coding)                    :: 25
            CDSs (with protein)               :: 25
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 7
            CDSs (without protein)            :: 7
            Pseudo Genes (ambiguous residues) :: 0 of 7
            Pseudo Genes (frameshifted)       :: 3 of 7
            Pseudo Genes (incomplete)         :: 4 of 7
            Pseudo Genes (internal stop)      :: 2 of 7
            Pseudo Genes (multiple problems)  :: 2 of 7
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GQ900409.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27067
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="NE 3874"
                     /db_xref="taxon:1280"
                     /plasmid="SAP050A"
                     /geo_loc_name="USA"
                     /identified_by="Kenneth Bayles: Department of Pathology and
                     Microbiology, University of Nebraska Medical Center, Omaha,
                     NE, USA"
                     /note="human clinical blood isolate"
     gene            complement(13..912)
                     /locus_tag="HHF21_RS00005"
                     /old_locus_tag="SAP050A_001"
     CDS             complement(13..912)
                     /locus_tag="HHF21_RS00005"
                     /old_locus_tag="SAP050A_001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(1011..2477)
                     /gene="msr(A)"
                     /locus_tag="HHF21_RS00010"
                     /old_locus_tag="SAP050A_002"
     ARG             complement(1015..2477)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2951..3625
                     /locus_tag="HHF21_RS00015"
                     /old_locus_tag="SAP050A_003"
     CDS             2951..3625
                     /locus_tag="HHF21_RS00015"
                     /old_locus_tag="SAP050A_003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <3683..4060
                     /locus_tag="HHF21_RS00020"
                     /old_locus_tag="SAP050A_004"
                     /pseudo=""
     CDS             <3683..4060
                     /locus_tag="HHF21_RS00020"
                     /old_locus_tag="SAP050A_004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            4057..4938
                     /locus_tag="HHF21_RS00025"
                     /old_locus_tag="SAP050A_006"
                     /pseudo=""
     CDS             4057..4938
                     /locus_tag="HHF21_RS00025"
                     /old_locus_tag="SAP050A_006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            5054..5983
                     /locus_tag="HHF21_RS00030"
                     /old_locus_tag="SAP050A_007"
     CDS             5054..5983
                     /locus_tag="HHF21_RS00030"
                     /old_locus_tag="SAP050A_007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            5976..6713
                     /locus_tag="HHF21_RS00035"
                     /old_locus_tag="SAP050A_008"
     CDS             5976..6713
                     /locus_tag="HHF21_RS00035"
                     /old_locus_tag="SAP050A_008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            6727..>6903
                     /locus_tag="HHF21_RS00040"
                     /old_locus_tag="SAP050A_009"
                     /pseudo=""
     CDS             6727..>6903
                     /locus_tag="HHF21_RS00040"
                     /old_locus_tag="SAP050A_009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            6960..7634
                     /locus_tag="HHF21_RS00045"
                     /old_locus_tag="SAP050A_010"
     CDS             6960..7634
                     /locus_tag="HHF21_RS00045"
                     /old_locus_tag="SAP050A_010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <7775..8410
                     /locus_tag="HHF21_RS00050"
                     /pseudo=""
     CDS             <7775..8410
                     /locus_tag="HHF21_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            8407..8937
                     /gene="sat4"
                     /locus_tag="HHF21_RS00055"
                     /old_locus_tag="SAP050A_013"
     ARG             8408..8934
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            9030..9824
                     /gene="aph(3')-IIIa"
                     /locus_tag="HHF21_RS00060"
                     /old_locus_tag="SAP050A_014"
     ARG             9031..9821
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10100..10671
                     /locus_tag="HHF21_RS00065"
                     /pseudo=""
     CDS             10100..10671
                     /locus_tag="HHF21_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(10840..11514)
                     /locus_tag="HHF21_RS00070"
                     /old_locus_tag="SAP050A_016"
     CDS             complement(10840..11514)
                     /locus_tag="HHF21_RS00070"
                     /old_locus_tag="SAP050A_016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(12184..12762)
                     /locus_tag="HHF21_RS00075"
                     /old_locus_tag="SAP050A_019"
     CDS             complement(12184..12762)
                     /locus_tag="HHF21_RS00075"
                     /old_locus_tag="SAP050A_019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(13026..13406)
                     /gene="blaI"
                     /locus_tag="HHF21_RS00080"
                     /old_locus_tag="SAP050A_020"
     ARG             complement(13030..13406)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(13396..15153)
                     /gene="blaR1"
                     /locus_tag="HHF21_RS00085"
                     /old_locus_tag="SAP050A_021"
     ARG             complement(13400..15153)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            15260..16105
                     /gene="blaZ"
                     /locus_tag="HHF21_RS00090"
                     /old_locus_tag="SAP050A_022"
     ARG             15261..16102
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16631..17050)
                     /locus_tag="HHF21_RS00095"
                     /old_locus_tag="SAP050A_023"
     CDS             complement(16631..17050)
                     /locus_tag="HHF21_RS00095"
                     /old_locus_tag="SAP050A_023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            17174..18144
                     /locus_tag="HHF21_RS00100"
                     /pseudo=""
     CDS             17174..18144
                     /locus_tag="HHF21_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /name="oxidoreductase"
     gene            complement(18316..18408)
                     /locus_tag="HHF21_RS00105"
     CDS             complement(18316..18408)
                     /locus_tag="HHF21_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18565..18912)
                     /locus_tag="HHF21_RS00110"
                     /old_locus_tag="SAP050A_026"
     CDS             complement(18565..18912)
                     /locus_tag="HHF21_RS00110"
                     /old_locus_tag="SAP050A_026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(18931..19548)
                     /gene="cadD"
                     /locus_tag="HHF21_RS00115"
                     /old_locus_tag="SAP050A_027"
     ARG             complement(18935..19548)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(20664..20858)
                     /locus_tag="HHF21_RS00120"
                     /old_locus_tag="SAP050A_029"
     CDS             complement(20664..20858)
                     /locus_tag="HHF21_RS00120"
                     /old_locus_tag="SAP050A_029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            20968..21660
                     /locus_tag="HHF21_RS00125"
                     /old_locus_tag="SAP050A_030"
     CDS             20968..21660
                     /locus_tag="HHF21_RS00125"
                     /old_locus_tag="SAP050A_030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            21945..22325
                     /locus_tag="HHF21_RS00130"
     CDS             21945..22325
                     /locus_tag="HHF21_RS00130"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(22524..>22813)
                     /locus_tag="HHF21_RS00135"
                     /pseudo=""
     CDS             complement(22524..>22813)
                     /locus_tag="HHF21_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(22833..23816)
                     /locus_tag="HHF21_RS00140"
                     /old_locus_tag="SAP050A_033"
     CDS             complement(22833..23816)
                     /locus_tag="HHF21_RS00140"
                     /old_locus_tag="SAP050A_033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            24242..24985
                     /locus_tag="HHF21_RS00145"
                     /old_locus_tag="SAP050A_034"
     CDS             24242..24985
                     /locus_tag="HHF21_RS00145"
                     /old_locus_tag="SAP050A_034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(25212..25397)
                     /locus_tag="HHF21_RS00150"
                     /old_locus_tag="SAP050A_035"
     CDS             complement(25212..25397)
                     /locus_tag="HHF21_RS00150"
                     /old_locus_tag="SAP050A_035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25402..25740)
                     /locus_tag="HHF21_RS00155"
                     /old_locus_tag="SAP050A_036"
     CDS             complement(25402..25740)
                     /locus_tag="HHF21_RS00155"
                     /old_locus_tag="SAP050A_036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(25986..26594)
                     /locus_tag="HHF21_RS00160"
                     /old_locus_tag="SAP050A_037"
     CDS             complement(25986..26594)
                     /locus_tag="HHF21_RS00160"
                     /old_locus_tag="SAP050A_037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     ARG             complement(17..912)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1012..2477)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(14..912)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             8420..8937
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             7812..8113
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             15261..16105
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(22321..22468)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(22527..22702)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(22834..23816)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          24243..24985
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttaatataag ttctactctt tcatacctaa ctctttcaat gccatcgttt catacgccga
       61 ttctcctgat tccatagcaa actcagcgat aaacattggg aatactgcat tgagttctat
      121 tatatgctct ttcattcgtg gccatatttc acctccagct ttaccgtatg ctgttataag
      181 ttgctctaat ccttcgtcgt cgaatacacg atggtgtcct ataaagtcca ttgatgggtc
      241 ggagtgggtt gcttcagtcc agtctatgag acctgtgacg tttgcttggt tatctaccat
      301 tatatgtcct ggatgtaagt ccccatgtat catggtcgca tgtcgaggcc atagttcgtc
      361 gttttctaac cattgtttcc atctgttcca taattcatct gatacgccat aagtttcttt
      421 aactttattc attcttcttt gaaagtcatt ttttatttct tgtatggttt tgatatttat
      481 atgctgaacg ttaatgtttt cttctggtat gttgtgtaaa tctacgagtg tttcagctaa
      541 tgtgttaata aagttttctg gtaatggttt gtgttcaatt tcccatacat aattttgtat
      601 ttctggatct attgtggctg cgggtttacc tgtaagtttt gggtaagcaa taaggtcttt
      661 tgcatgtact ttccacttcg gtatttcaaa tgaaacattc ttctgtaaga agtctaccgt
      721 ttgtttttcg ggttttgttc gtttataaac gtcaggtctt cttggtagtc tcaaaaccca
      781 ttctactcca tgtttatctt ttccaaatgc aacttgaaaa tcaagtcccg attcattcaa
      841 tgagattgtt tgaggttgga tgtgtaattg atatttttct gcacatttaa taatttcatt
      901 atgtcgagtc attttattgg atccttattt ctattatatt tttcttgtga acgtattttt
      961 tatattgata taaatgaacc taatattcaa tataaattag tgtatagttt ttaagttata
     1021 tcatgaagag attgtcctgt taattcccat tttttatctg atacatgttt aacaaacctt
     1081 gtatcatgtg atgtaaacaa aatgattcca ggatatttat tcataaacat ttctaatgct
     1141 tctaatgttt taatatctaa aaaattagtt ggttcatcca aaattaacat attcgctttc
     1201 gttgaaaata atactgctaa cgataatttc gttctttccc caccactcaa aacattacaa
     1261 gaacgatcaa gtgcttcatt taaacccaag ttatttaaaa tagctctact gaatgattct
     1321 gatgaatccg tttcatccat taaatattgc aataatgaaa cgtcacgcat gtcttcataa
     1381 gcaagttgac gatagtatgc catttgcact ttaggagaac aatcaattcc ctctatttgg
     1441 tggtaaatag cttcaagtaa agttgtctta cctacaccat ttgcacctac gagcgctata
     1501 tttttgccat atggtatttg gaatcgtact tgtgttagca gtttttgact tcctttaacc
     1561 aatgttagat tttgtgcaat gattggataa ttattatgga tatcataaat tttattttgt
     1621 gggaaattga attcatgata actttgtggt ttttcaactt cttccaaatg ttccattctt
     1681 ttttcaatat gcttagcttg tttttgagca gccttctcaa ccgtgccttt ttgttttgat
     1741 gcacttaaac gatctggtgc tatacttttg tttttttgtt ttgatgatgc ttgtgccatt
     1801 tgttgcgctt gatttcgttt agctttactg gcttgggaca atctttgttt ttcacttata
     1861 tactgttcat attgacgttg ttgttctaac tgttcttgtt catattgatt ttgatactgt
     1921 gtgtaattac ctttaaacac tcttattgtg ccatcttctt gtatatccca aattgtgtca
     1981 gcaatttggt ctataagtgc tctatcatga cttactataa ttaaagtacc atagtaatat
     2041 tttaaaatat ttttcagata atctttacca attttatcca agtgatttgt aggttcatct
     2101 aaaagtaata tcggactata atttgatatg acattagcta atttatattt tgctttttca
     2161 ccaccactca tactgtcggt tgtatgcata ggtatatgga gttcactcat taaactaccg
     2221 tctaacgtgt taaaatcatt ttccacatcc atgttaagct gttcaaaata ttgaatttcg
     2281 ccaaccgttt caactgttcc agattctggt tttgtttttt gagcaatcat atttagtaat
     2341 gtggttttgc cagtaccatt acccccaata agtgctattt tttcaaattg gtaagcgtaa
     2401 agatgaccga tgttaagtga tcgtaaatct gtcaatttat gattgatttg gttaaattta
     2461 attgtatatt gttccatatt tatacactcc ttgtatattt aaaggacgtg tacgcaaaaa
     2521 aatgagacag gctactcccg tctcattcac attacacttt caaacactta aaaatttatt
     2581 atgatgtttt agtatttgaa agcgtttatt attcctatcg aaggataaaa aatgacataa
     2641 gtcatcctat gagtgtgtat tgcggacaag cctttttgaa ttaatttagt tttgtattca
     2701 aaaaggttta tttgagtctc atagaagctg tcattttaat cctccttcat cgataaaata
     2761 gtaatgttaa tataacattt tgttggtttt tttacaatat atctctaagt agaaagatta
     2821 tataacaaaa gtataaaaat acaattttag attgattata catctcctta atttagagtg
     2881 tactcataaa atacggttct gttgcaaagt tgaatttata atataatttt aacaaaaagg
     2941 agtcttctgt atgaactatt tcagatataa acaatttaac aaggatgtta tcactgtagc
     3001 cgttggctac tatctaagat atgcattgag ctatcgtgat atatctgaaa tattaagaga
     3061 acgtggtgta aacgttcatc attcaacgat ctaccgttgg gttcaagaat atgccccaat
     3121 tttatatcaa atttggaaga aaaagcataa aaaagcttat tacaaatggc gtattgatga
     3181 gacgtatatc aaaataaaag gaaaatggag ctatttatat cgtgccattg atacagaggg
     3241 acatacatta gatatttggt tgcgtaagca acgagataat cattcagcat atgcgtttat
     3301 caaacgtctc attaaacaat ttggtaagcc tcaaaaggta gttacagatc aggcaccttc
     3361 aacgaaggca gcaatggcta aaataattaa agcttttaaa cttaaacctg actgtcattg
     3421 tacatcgaaa tatctgaata acctcattga gcaagatcac cgtcatatta aagtaagaaa
     3481 gacaagatat caaagtatca atacggcaaa gaatacttta aaaggtattg aatgtattta
     3541 cgctctatat aaaaagaacc gtaggtctct tcagatctac ggattttccc catgccacga
     3601 aattagcatc atgctagcaa gttaaacgaa cactgacatg atatattagt gattagctat
     3661 attttttact ttgcaacaga accagccatt taatatgact gttacaatta ctaagattca
     3721 agcactatta cgccgcacgt atgatttcac cactcaagtt aataatttaa cagtagatga
     3781 ttgcgagtta ctacttgatg cagcaaagct taaatttaat gaagaaacca tagacctgac
     3841 acacactgaa ttgcaaatca tgcatagctt attccagaac aagggcaaat tcgtcagtcg
     3901 taatgcgtta atcgaaaaat gctgggaatc agaacacttc attgatgaca atacgcttgc
     3961 tgtcaacatt acacgtttac gcaaaaagct acaaaaacta ggacttacag attttatcga
     4021 aacgaagaaa aatgtcggat atcgtgtagg tgacgtatga atttcttgaa atcaatccaa
     4081 cgtgaaattt atattgtcat ccttacttgt gctttattct actttatatt attcatgtat
     4141 aatgtgccga tgcaagcata tatgattggt ctaggtattg tattgtttgt ttcaatgatt
     4201 tactggggta tccattacat gaactttaaa aaagaataaa cactacagga acagaacgaa
     4261 gatttaagaa tcgaaaacca taaacttcgt aatgacttta ttaactacca aagtgagtta
     4321 gagtcatatt ttttaatgtg ggtgcatcaa atcaagacac cgattacagc atcaaagtta
     4381 ctgcttgaag atcctgatga acacgtgatt tctaacgtgc gtaatgaagt cttacaaatt
     4441 gataattaca cgaatcttgc actgaactat ttgaaactca tgaaccaaaa gacatacatg
     4501 gtctttatgg aagtgagtgt agatgaatta attcgaccac tgattaaacg ttatgcgata
     4561 cagtttattc atcatcaaac aaagttgcat tatgagaaaa gtgaagcggt tatattaaca
     4621 gatgccaaat gggcatcaat tatgattgag caaatattaa acaatgcatt aaaatatgca
     4681 cgtggcaaag atgtgtggat tacgtttgac gaaaatacaa agaaattatc aatccgagat
     4741 aacggtatcg gcattaatgc gagtgattta ccgaaaatct ttgataaagg tttctcgggc
     4801 tataacggta gaataagtga gaaatcaagc ggtattggtt tatatattgt cagcacaatc
     4861 tcaaagcgct taggccataa agtaagtgct acatctacat taaacgatgg ttcaatattc
     4921 accattcaat ttaaataact ccaatctttc atttttgtaa gattagcggc tgtttttgta
     4981 agaatagata aaggcagcct tttctaatcg cgcgtaagat aaaggtaaca acaaactaag
     5041 aaaggtgcca gaggtgaaaa atttgaataa tataattgaa ataaataact taacaaagca
     5101 atatggaagt cagatagcag ttaataattt gagtataact gttgaaagtg gacaaattta
     5161 tggtttttta ggaagaaatg gtgcaggcaa aacaactact ataagaatgc ttttaggctt
     5221 aattaaacct acgaaaggta atattaaaat atttgaaaaa gagttcgaaa gtaataaaac
     5281 tgaaatttta aaaaatattg gtgctatggt tgaaacgcca ggtttttata gtaatttgac
     5341 agctaaagag aacttaacta taaatgctaa aatattaggt atacaaaaag aaaatgcaat
     5401 tgaagaagtg ttagaaatag taggactagc ttctgaaaaa gtaaaattgt ttaaaaatta
     5461 ttctttaggt atgaagcaac gtttagggat tgcgagagct ttattgcaca atcccgaatt
     5521 attgatactt gatgagccga cgaatggatt agatcctatt ggcataaaag aaattagaaa
     5581 gttgattaag gatctggctc aatctagaaa tataaccatt ttaatttcaa gtcatatatt
     5641 gtcagaaata gagcagttag tagacaaggt gggtattatt cataacggag ttttgttaga
     5701 agaaattatg tatgaagatt taaaaaaaaa gaacagacaa tttataagta tatcagtatc
     5761 agatgaagaa aaagttgcat gtttgttgga aactaacttc ggaatttatg actataaaat
     5821 taaagaaaat ggcgaattta aaatttattc acatattgat agacaacaag aaattaatag
     5881 attattagta ttaaacaata ttgatgtttt ccagatgaga gtgatagaag ataatctaga
     5941 aacttatttc gaagacttag taggaggtgg cacaattgga taatctactc cgtacagaat
     6001 ttattaagtt aaaaagatca tatatgtttc taataagtat tttaggtaca tgcgtagcac
     6061 cttttatggt ggttgtagct tcttttatta gtatgcggac gaaagtaccg actcctaata
     6121 ttgtatttaa acagttattt gaagaagtca gtttatatca tatgctaatt attggacctc
     6181 ctctatatgg ggttataata gcctatttgt ttggaagaga atatatagaa gatactttaa
     6241 aaaacttatt aattatacct atatctagag aaagtttttt agtaagtaaa ataatattat
     6301 tattcttgtg gattcaaaca ctatctgtta ttgcatggtt gctaacttta atgctaggta
     6361 tgctattgca ttttcaaggg ttaagccaga gtttaataat tgattcattc tttacatttg
     6421 ttattggcgg agtgttatta tggatattat ctccaccaat aattattttg tcgatatatt
     6481 ttaaaaatta tgttcccaca attgttttaa ccataataat tactttgata aatttaatga
     6541 ctgctaattc tgaacataga ggattatttc cttgggctgc agttggagac atatctagag
     6601 gaacattacc taatacttat ccatttctat tatctttaat tatcataatt gttacatcta
     6661 tattcagtgt aattatatta ttctcatact ttaaaaaaac tgatataagt taaaaggagg
     6721 agaaaaatgg gttttataga gcagattaaa gcatttattt taggtgtagt tgaagggttg
     6781 acagaatttg ctccagtatc atcaacaggt catatgatta ttgttgatga tatgtggtta
     6841 aacactgctg acgatttagg aagtgcgtct gcaactactt ttaaggtggt aatacagtta
     6901 ggaggttctg ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta
     6961 tgaactattt cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact
     7021 atctaagata tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa
     7081 acgttcatca ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa
     7141 tttggaagaa aaagcataaa aaagcttatt acaaatggcg tattgatgag acgtatatca
     7201 aaataaaagg aaaatggagc tatttatatc gtgccattga tacagaggga catacattag
     7261 atatttggtt gcgtaagcaa cgagataatc attcagcata tgcgtttatc aaacgtctca
     7321 ttaaacaatt tggtaaacct caaaaggtaa ttacagatca ggcaccttca acgaaggtag
     7381 caatggttaa agtaattaaa gcttttaaac ttaaacctga ctgccattgt acatcgaaat
     7441 atctgaataa cctcattgag caagatcacc gtcatattaa agtaagaaag acaaggtatc
     7501 aaagtatcaa tacagcaaag aatactttaa aaggtattga gtgtatttac gctctatata
     7561 aaaagaaccg caggtctctt cagatctacg gattttcgcc atgccacgaa attagcatca
     7621 tgctagcaag ttaaacgaac actgacatga tatattagtg attagctata ttttttactt
     7681 tgcaacagaa ccatcatttt tattaaaata ctcttttgta aaatctttct gctcttcaat
     7741 gtatttaatt tctttacctc taaatctatt atagctattt gatgattaca ataaaattga
     7801 tcttacctta ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa
     7861 ggttctaatt gataaagatt gtagaattaa aagggacata gttccgactg atatagatta
     7921 tcatgtaaga aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt
     7981 aacaccttat gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt
     8041 taatcagatt gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac
     8101 aggctttaaa tgaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga
     8161 tttgtgggag aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc
     8221 attatttcta tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca
     8281 ttatgcctat ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa
     8341 atacactggt aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg
     8401 ggaacagtga ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa
     8461 ccatttgagg tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca
     8521 gaattactct atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat
     8581 gaggaggcag attgccttga atatattgac aatactgata agataatata tctttactac
     8641 caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat
     8701 atagaagata tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc
     8761 aatatatcta tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag
     8821 gacaataacc ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc
     8881 gatactatgt tatacgccaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
     8941 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
     9001 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
     9061 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
     9121 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
     9181 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
     9241 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
     9301 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
     9361 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
     9421 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
     9481 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
     9541 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     9601 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     9661 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     9721 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     9781 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     9841 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     9901 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag agttctatat
     9961 tagagatgta aagagttttg gtgaagaggt ttgtgagtat ggcttttata accagggtgc
    10021 aatgagaagc actaacagca gctagcttaa gaacgcatag gatatacttt ttatggaagt
    10081 cacagaggag gaataaaatt tgaacaggat taacagagta acctctattc ttattcagct
    10141 gcaatcaaaa aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg
    10201 acagtttaca gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc
    10261 ggaaaaggat attttcttgt agagggcttc ctacttctgc cggtaatgtt tacagcggcg
    10321 gaagtgggtg cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt
    10381 ataaaggatt ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa
    10441 aactatgcac aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat
    10501 acattggcgg ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata
    10561 tcaattcaat atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata
    10621 tcactggggt tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat
    10681 ataggaattt tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa
    10741 gccatgatgg ctctttggaa caaatattaa aacaaatgct ggttctgttg caaagtaaaa
    10801 aaatatagct aaccactaat ttatcatgtc agtgttcgct taacttgcta gcatgatgct
    10861 aatttcgtgg catggcgaaa atccgtagat ctgaagagac ctgcggttct ttttatatag
    10921 agcgtaaata cactcaatac cttttaaagt attctttgct gtattgatac tttgatacct
    10981 tgtctttctt actttaatat gacggtgatc ttgctcaatg aggttattca gatatttcga
    11041 tgtacaatgg cagtcaggtt taagtttaaa agctttaatt actttaacca ttgctacctt
    11101 cgttgaaggt gcctgatctg taattacctt ttgaggttta ccaaattgtt taatgagacg
    11161 tttgataaac gcatatgctg aatgattatc tcgttgctta cgcaaccaaa tatctaatgt
    11221 atgtccctct gcatcaatgg cacgatataa atagctccat tttcctttta ttttgatgta
    11281 cgtctcatca atacgccatt tgtaataagc ttttttatgc tttttcttcc aaatttgata
    11341 taaaattggg gcatattctt gaacccaacg gtagaccgtt gaatgatgaa cgtttacacc
    11401 acgttccctt aatatttcag atatatcacg ataactcaat gcatatctta gatagtagcc
    11461 aacagctaca gtgataacat ccttgttaaa ttgtttatat ctgaaatagt tcatacagaa
    11521 gactcctttt tgttaaaatt atactataaa ttcaactttg caacagaacc tcatttacta
    11581 tatgggcatc tctttcatta ttaatacaaa gctttgtatc tccgatatta ggcaaaggtg
    11641 taaacgaatt aggtgatact ataggattca acattatatt aatcgtttct ttaataatga
    11701 ttatcttctt attttttata aatcgtagta aaaatatctc ctatgattat ataaaagttc
    11761 aaagaggtga agccaatgaa taaattagaa aaatggtctt tggtatttat tatttttaca
    11821 tttctctctt cattagcact tttatatttc aaatataatt ttagttcggt tatgccagtc
    11881 ctaagtcttt ctattttaac tatactaata ttgttgacga gtattattac tgtagtttca
    11941 gttaatgatg aagatactta aaacgttcat tagtgaaaca ggtattatat taaaaaagcg
    12001 tacgaatttg tacgcttttt tcttgtgtta ttattaaaat ctcataacag gaaaatatta
    12061 tgagatttta gacgctgtca gaacgtctct tttacatcga gtgacattga atcaaagtct
    12121 ttgtatgtta atgatatata aaattattta gtagattcat tatagtaagc tagattagtt
    12181 gctctacttg tttttattct cttttgcctc taatttattg agataacgat aaatagttgt
    12241 acgtgaaact tgccactgct ctgcaattgt tttaattggc gtaccattat cataaagtgt
    12301 cttaagtaag tttaaatctt gtttatttaa tttttcaggt ctacctccat atcggcctct
    12361 agcacgtgct gcaattcgac cggctgatga tcgctctaaa attaaattac gttcaaactc
    12421 tgcaaatgct gcgaataaat gaaataataa ttgtcctgta gaacttgatt tatccatcgt
    12481 tatattttct tctaaactat gaaaactcac acctcgttcg ttaagttcat taactaacgt
    12541 gattaaatcc tccatgttcc gtcctagtct atctaatctc caaacaacaa tcgtatctcc
    12601 tgacctcgca aattcaattg ctttatctaa accaggtcgc ttactttttg aaccactcat
    12661 atggtcatta aatatctttt cacaaccata tgtatttaat cgatcctcct gtaaattcaa
    12721 attttgtaat ccagttgaaa ctcttgcata acctattttc aaaatacaga cctcctatat
    12781 acacctttag tgtaccataa cttgattacg aggtcttttg tgaacataga ttttttgttg
    12841 ggtttttgaa cacataattc tatgtaatac ttacttattt agacaaaaaa caagagtgta
    12901 cagaaaatgg ttattttctg gacactctca tctttaataa tatattttaa atgtcattaa
    12961 caaaactaat ttaataagag tcaagtatgg tttacatatg tattatgttt gaaacatacc
    13021 tctaattact ttttactaat atcatttaaa atgtctcgca attcttcaat ttctttgtta
    13081 tttaattctt catttttcgc aaaattcagc actaaacttt tcatatcccc tccatacagt
    13141 ttattaagaa aggttttagc agttttcatt ttaatatcgt cttctttaat atttgatgag
    13201 taaaaataaa tattttctga tttgtatcgt tttataatct cttttttata tagtcttgtg
    13261 attaatgttc taatcgtttt atcactaact tctttatatt tttgaatttc aactacaatt
    13321 tcattagctg atactgattt tttatcccat attatattca taacatccca ttcagccata
    13381 gatatttcaa cttgcttatt ggtcatttaa aacacccatt ccttttaata ttttttcact
    13441 tattaattca gcatttttcc cagacgggtt tccatctgat aaatgtgtag caaaataata
    13501 cttatcatga tttgtaatta cgtaacctac aaaccaccca ttattatact tcccgtttac
    13561 tatacctgta cctgttttcc catacagttc atacttttca tttttcttaa tcaataatga
    13621 agaagataat tgattctttg cttttttact aaaatggtta ttttgttcca tcatattttt
    13681 aaaaactatt acttgttcaa gattagatat tttcaaacta tcttccatcc aatagctttt
    13741 ataacttccc aaattttcat taccataatt taattgcttg agttgagccg cagtatagtt
    13801 ctttggtatt tgattactaa tacgttcgaa gtaccaatta actgaatttt gcattgctgt
    13861 atttaaatct tgttccttat tccaagactc gaaaagataa tgtttatgat tccatgacat
    13921 acgtgaattt ttatcactta taatatgacg gtcaagtcca aacagtgcta aataaatttt
    13981 gtaagttgaa tcaggagaat atctttttct actttctttt tcattataaa tatagtattt
    14041 gtctttcttc atgctgtaca taacgaaaga tccactattt gaaccaaaat ttttactttc
    14101 atctaaaatt tggtaatcgc tttgtaaggg ctttttataa ttataatcag ttaaggattg
    14161 ccccattaaa aactggcttt gaattatcat gataaaaaaa gtaaaaatac aaataaaaat
    14221 tagaattaat tttgactgct ttttcagatc ggcttctttt atattaatta atctactttt
    14281 gagtaatgat tttttaccat taaatgaatg gcttaatata tttttgttgg aaaatggggt
    14341 ttttaatacg gagtccataa tagattccgc ataagtttta aattcatttt tgttaatatt
    14401 attaaggaca aatctatcgg cttctacttc attgtcatga attatctttc tttttacaat
    14461 atgtactaat ggattgtaac tcataataat agagaagata ttaaagataa ttaaatgtaa
    14521 agtatctcta tttttagcat gagcatattc atgcagtatt atatatttta gtcttttatc
    14581 aattacactt ttaaaatatg aactaggaat caaaataata tatttcccat accaaaaagt
    14641 tattggagat tgaatagcct ctgcttttcg aatcacaata ttttttttat attgatggtt
    14701 gaaaagtatc gtatctattt tatttttttc attttcgttt agataaagtg actgtttctt
    14761 taaatattta agatataata aggctttcaa aaatttaaaa cttaaaataa taactaaaac
    14821 tatccaaata actgtgcaga tattatcaat tgaatcccaa ttaaacttat ggatatctgt
    14881 tgtgaactct tgaataggtt tggtggtatt tatgttatgg ttcaaatcgt gtgacttact
    14941 ttcaactgtg ggcgcttgat tattcacatt attaaatttt ataaaagaga atttaattgg
    15001 gataaaagga attaatccag caagcatagt tagataccaa actttataat ttaaactata
    15061 attaaaatag cgttttaata tgtacctaaa aaatactaac aatagaaata taaaacaaaa
    15121 gcttactacg ctcattatta gtaatttagc cattttgaca ccttctttca aatatttata
    15181 ataaacaatt gacatcaata ttacaattgt aatattattg atttataaaa attacaactg
    15241 taatatcgga gggtttattt tgaaaaagtt aatattttta attgtaattg ctttagtttt
    15301 aagtgcatgt aattcaaaca gttcacatgc caaagagtta aatgatttag aaaaaaaata
    15361 taatgctcat attggtgttt atgctttaaa tactaaaagt ggtaaggaag taaaatttaa
    15421 ttcagataag agatttgcct atgcttcgac ttcaaaagcg ataaatagtg ctattttgtt
    15481 agaacaagta ccttataata agttaaataa aaaagtacat attaacaaag atgatatagt
    15541 tgcttattct cctattttag aaaaatatgt aggaaaagat atcactttaa aagaacttat
    15601 tgaggcttca atgacatata gtgataatac agcaaacaat aaaattataa aagaaatcgg
    15661 tggaatcaaa aaagttaaac aacgtctaaa agaactagga gataaagtaa caaatccagt
    15721 tagatatgag atagaattaa attactattc accaaagagc aaaaaagata cttcaacgcc
    15781 tgctgctttc ggcaagactt taaataaact tatcgcaaat ggaaaattaa gcaaaaaaaa
    15841 taaaaatttc ttacttgatt taatgtttaa taataaaaac ggagacactt taattaaaga
    15901 tggtgttcca aaagactata aggttgctga taaaagtggt caagcaataa catatgcttc
    15961 tagaaatgat gttgcttttg tttatcctaa gggccaatct gaacctattg ttttagtcat
    16021 ttttacgaat aaagacaata aaagtgataa gccaaatgat aagttgataa gtgaaaccgc
    16081 caagagtgta atgaaggaat tttaatattc taaatgcata ataaatactg ataacatctt
    16141 atagtttgta ttatattttg tattatcgtt gacatgtata attttgatat caaaaactga
    16201 ttttcccttt attattttcg agatttattt tcttaattct ctttaacaaa ctagaaatat
    16261 tgtatataca aaaaatcata aataatagat gaatagttta attataggtg ttcatcaatc
    16321 gaaaaagcaa cgtatcttat ttaaagtgcg ttgctttttt ctcatttata aggttaaata
    16381 attctcatat atcaagcaaa gtgacaatag cattttacaa gtatttttta ttgttcgatt
    16441 agggtaaacc taaataatac ataaattata ttacaatatg tttattatag aggctaaagt
    16501 atcttagaaa tttggatagt aggtttttcg ggaataaaag tatagttggc tttaatatat
    16561 aattaagcta agctatcatt tatatttact cgattataat tcgcacttca acttttttat
    16621 aacgtaaaaa ttaaaacgta gttttattta tctttagtaa tatcttttta aacactacag
    16681 tttcttcatt agttaaatta gcgaagtaat gattattaag ttgataggct ttcttttcta
    16741 atgttggcca taagtctttt gctttatttg tactgtttat tagcacagtt cttctatttt
    16801 cattatcagt ttgacgtgtt attagatcct ttttggacat cttatctaat attccagata
    16861 ttgttgaagg ttctaaattt aaagtattac caatcgcttt aggtgtattc aaattactat
    16921 taatcaagca attcaaaaca ccatattctg ctggagtaat attataggga cttaataaac
    16981 ttttaaaatg tttaaaaact ctattctgag aagtactcaa caaataattt atacaattat
    17041 ctaattccac aactaaaacc tctcttaaat cattagtatt gactcgctta tcatatcatg
    17101 ataagttttg taggaaaata gttttgcaac aaaaacatac ttctacaaaa caattgtgaa
    17161 agaaggctaa taaatgttca atgcggtagt agtgagaaaa agtgcatcaa atgttagtta
    17221 taaagtagaa aaagttgatg aatctcattt atcgaagggt gatgtattag taaaagtggt
    17281 atactcttca ataaattata aggatatgct agctttacaa tataaaggcg gtgtaattag
    17341 agattatcct atgattcctg gtatagattt tgcaggtatt gttgaatcaa gttcgaatga
    17401 taagtttaaa gaaggcgata atgtattagt tactggttat gatgttggcg tgacacatac
    17461 aggtggattt cagaatatgc acaagtgcct ggagagtgga ttgttcctat tccccaagaa
    17521 atgtctatta aagagtctat ggtatatggc acagccggtt ttacggcagc attatcaatt
    17581 tttgaactag aaaaatatgg aatgaatatc aaatcacaac ctgaaatttt agtgtctggg
    17641 gctacaggtg gtgtgggcag tgttgctata caaattttac ataaaattgg atatgaaaat
    17701 atcactgcta tcgtaagaaa agaaaagcaa atagaaatcg caaaaaaatt aggtgcaaaa
    17761 caagtaataa taattgaaga tgataataaa ccgcttaaaa aaggtatttt tgattatttc
    17821 ttagatacag tggggagtaa tgtaacatta tacggtttaa aacgtctaaa ttatcaaggt
    17881 gttgctactg tatgtggaaa tgtagcagga aattcactta acgctaatat attaccgttt
    17941 attcttagag gtattaaatt aattggcatt gattctgtat atgttgatca taatatccgt
    18001 gaagatatat ggagtaagtt agcaaatgaa tggaatatag gaaattcact tctatacaat
    18061 gaaattggat ttgaagaatt ctataaaacg atagatcagc ttttaaaagg acaacattta
    18121 ggaagaacta ttttaaaagt ataagtgtga gtattcatta atacatttac tattaattca
    18181 atcattttgc atttctctac taaccagtgt tataatttat ataacgaaaa tgattaacaa
    18241 ttaatgcacc aatccccaca ctattgcagt agtgtgggga ttttttcgat gctggcttat
    18301 aaagtcgcct attaattatt tgttgcgttt actaagccaa taagtataat acgcaacagc
    18361 acagccactg atgactggtg ctatgatgtg aacgaaaatg attagcaaag taatgcacct
    18421 cctctcttcg tcaattgacg cctgagagat aggcgactct attattatac catctgtgaa
    18481 tatacaagca tatctacttc cgataagtcg tcttatgtta tataactttg ttttttatag
    18541 tatcaagaca agaagaaact cgtttcaaaa accctcatga tttttagaga aaaactctct
    18601 tatttcatcg tctttaataa aataatatgc catctttcca tctttataaa aatcaagtac
    18661 ctcattttta tataaaagcc ttaaatgatg tgaagttgaa gcaacactca ttttcaatat
    18721 caaagaaata tcacaaacac acaactcatc ttctttaatc aaagataata tgattttcaa
    18781 tttcttctca tcacaaattt tttctaaaat gttaagtaat ttcttagatt tatcatcttc
    18841 taaaaaactt aaagcattgt taactttatc ctcatgtaca cagatcacat cacaagtatt
    18901 ttcataactc atataaaatc acaccctaaa ttaaaatata aatcctaaaa ttgtttgaat
    18961 agtgtcattt tcaataataa taaataaacc taaagctata taaataatag ccataatcca
    19021 acgactaaat ttctcaacaa tttctccaat tcctggaata ttagctaatt tttgtgcagt
    19081 aaacaccaag aagaaaatta aaattaaaaa gacaaacaga gtaagtaata aattagtaac
    19141 acttaatgtc acaaaatacg gaacaaataa accaatatta tcggcgccac aacttgctat
    19201 cgtaacaatt gcaaccgtac caactaattt agacaatcct ttttcattca attctttttt
    19261 agctctcttt tctccttcac aatcatcata aatagccact ttaattccaa gataaattgg
    19321 tattaaaccc aataaaccta atatccactt ttctggaaca taatttaata caaaagctaa
    19381 aaacaaacta actaatatta aaataataga ccctaaatat tgaccaacat aaatatctct
    19441 atattctttt ctagtctttg ctctagcaaa aaatattaat aaaattacta ataaatcaac
    19501 tgctgtagca atataaagaa cagcagcagc aacaaccgtt tgaatcataa tacacctcat
    19561 tcaaaaatat ttttgaatgt attataactt atatttttaa ataatcatag gtgctttatt
    19621 ccaattgctt tattgacgtt gagcctcgga acccttaaca atcccaaaac ttgtcgaatg
    19681 gtcggcttaa tagctcacgc tatgccgaca ttcgtctgca agtttagtta agggttcttc
    19741 tcaacatcaa taaatttttt cggcataaat gcgtgtctat gcgtagacat ggagacactt
    19801 cagaattatg gagtgattac atgagtttaa ctatttttct ttattcagtt ttaggaagtt
    19861 tattagcaaa ttatatctac gaaaaatctt caaaataaat aactttttcg gttctacttt
    19921 gtacacttta tctacctggt agacctaatt gttattgctt tacaggtcta aaattcgtcg
    19981 ttataatcta gttaaatccc gtaagggcgc acttatacgt cggataaatc gacatgtgca
    20041 aaaacgtaat cgaccttcgt cgattttttt atttcaaaat taaagaaacg gcttgagata
    20101 ttccgagcag ttataaaaat taatttgcgt tgaatattgc tactacattc ttgaaaaagt
    20161 gatgtagatt tatagcccat aacttttttg aattacatcg acgatacggc gtcgaaagaa
    20221 aaataaatag accgtatgaa agaaaaagct acctcacttt atctggggta gcttttattt
    20281 tttatgccct tattttgaat tttaagaggg cattttaaag atttaggggt gattcatata
    20341 gttttatatc taaaacttat atatgctttt aaaacgcaaa tatgagccaa ataaatatat
    20401 gctattttca aaaacaaaaa tttgagcaaa aacaataact atttttagac actgcccatt
    20461 tacatgcaaa ttaaaaatta gcataaaatt ctttaaaact tccccacgtt tttctaaatt
    20521 cctgtagggc gtttttatca aaaatcaaga caagaagaaa ctcgttcaca ctcgtttcaa
    20581 aaaaacaaga aatctaatct atacacctac cgttttccaa ccccctcaaa gcatacaaat
    20641 taaaaacaaa attattcata atcttacttt cttttaacaa aaacataaaa accataaata
    20701 gacaaattaa ctatcaaagg caataaacag tataaaaaaa ccacgaataa atcttcatca
    20761 acatctaaaa taaaaaagaa taaaacaatt aacaaaatac taattaacaa acctaaaagt
    20821 ggcaaacttt ttatatattt ttctaaattt tcattcataa aatagactcc tttcaaaaat
    20881 atgtttataa atatattaaa ataaatattg attttataaa gcgcttactt atacaattaa
    20941 aatatcttat tatcttggag gtatcaaatg aaaattataa aattattttc aataatttcc
    21001 ttgttcctac tggtatttag cgcgaatttt tctaatgctt acgcaaatga agaacaaaaa
    21061 agttctttac tagaaaatca aaaagaaaaa ttgaaaagca aaaacatcga agtatcacaa
    21121 atgaccaaga aagaaataag ttttctagaa caattgcaaa ataaaaatga agatatgcaa
    21181 aaattcgaaa agcaaatgaa aaaagaagga tttaaaaaaa taaagctaga agacaaaaat
    21241 tctaaattaa aatatctagc tacagaagca aatgataaaa atgcatatgg ctacatagct
    21301 aataacgctt ataaaaatga aaaaacaaaa gaaattgtag tttctgaaac aatatatgat
    21361 aactacaaca aaaaaatcac aaaattcatt gccgaaaaaa gaagtatgac tgaaaacaaa
    21421 gagggaaaaa tacttattaa caaaaattac gttgaatata aggctgaaaa agttgataaa
    21481 aacagaccgg taacatatgc aggattcaaa tggaacggca aagcattcgc ttgtagtatg
    21541 gctggacttt atgcatgtgc tcactactgt ggagtatggg caatcgtaaa tccaatagcc
    21601 ggcggtgtat gtgaagcagt ttgcggaact gcatttgcag ctggatgctc tgtaggttga
    21661 ttttattcca attgttttat tgacgttgag cctcggaacc cttaacaatc ccaaaacttg
    21721 tcgaatggtc ggcttaatag ctcacgctat gccgacattc gtctgcaagt ttagttaagg
    21781 gttcttctca acatcaataa attttttcgg cataaatacg atgttcctta tttatcctca
    21841 taaaaaacaa tagctgaaat atataaccaa ttactgtgtg tttgaatttc taatacatga
    21901 atatcattct ttaaaaacct attaacttgt ttatctaatt gacgatgagt aaaagtagcg
    21961 aaagttttaa tcttcatgat atctctcctt ttataaaaat agcaatcctt attacaatat
    22021 taaacacttt tattttggat tttaagaggc attttgaaga cttagaggca aatcatatag
    22081 gttttgtact taaaaatcta tacagtctct taaaacgcaa atatgagcca aataaatata
    22141 tgctaatttc acaaacaaaa atttcagcaa aatcagtgac taatttttta gatactgccc
    22201 atttacatgc aaatttaaaa attagcataa aatactttaa aacttcccca tgtttttcta
    22261 aattcctgca gggcttttct tatcaaaaac ttagaaattt taatttaact ctaaaatctc
    22321 cgtaagagca taagggaaat ttgctatcat tcaaaaatga tagatctggc aaggccagac
    22381 attccaaggg ttttaagtta ttttaaagtg atatcataca aagctgtagt gtcacacttt
    22441 tgtgacacta catacagcat ttgtcacaaa aataagacag cactttttta cagaaaaaca
    22501 ataaaaaaag acatcagtta tcactaatgt cttaaataat aattttgctt ttcgaaattc
    22561 caaattgcgg taattgaatg tgcttttttt cttcgtctgt cgttttatct tcatcacttg
    22621 tattaatcaa attaccatct tcggcatcgt ctaagtttaa aattttatgc ttttgtttaa
    22681 gcaatccacc ataacttaac atacgttttc gatacaaacc tttttctaaa tcacttacaa
    22741 tttcttgatt tttttcgtcg tcatcagtta aaaagtcaga tgatttaacg gaatattttg
    22801 atgtctcttc gagtgttata aaatcatttg aattattgat taaagatatt atattgtttc
    22861 atgtttttac ggcgcatata aagggcatgt gtttcttcaa gttcagttag aattgtttgc
    22921 attaaataag cttgcattga cttgattgtt tccttttggc ctttaactcc cctatcatgt
    22981 atagcttttt taagtctttt taaagaagtt aatatttcat cctcaatgtc ctctaacatg
    23041 taatgcatat cttcatgcct tgaattaaat gatttttttg ctttaagaat aacagccttt
    23101 atgatttcta aatctctata atcatatttt aataaataat tagttagttg ttctgggaat
    23161 tcttgcaata gcatttcttt atcatcaaaa ttatgtgtaa attgatttga atgatttgaa
    23221 tgattactaa tttcattttt gtactttata tcattcaagt cattcatatc attattctca
    23281 gtatcattaa agtcaatgtc attaaagtca gtatcattag tgttcgattt tcgaacttct
    23341 ggacgttcga ttttcgaact tctggacgtt cgattttcga acttctggac gttcgatttt
    23401 cgaacttcct tctcgccgta aggttcaaca tcgttttctt ctttttctat tttgtaaata
    23461 tcacgttctg tgacaatagg tttcattaaa tatagaatat ttggtttatt taaaccacgt
    23521 cgtttttgaa tgagtagacc atcgttttct aacccttttt ttatttttgt taacttttct
    23581 tttttacaat ttaagatttc cattagcttt tcatttgaat aaacaaagta aatgttacca
    23641 tcttcatcaa cccagctatt tttaatagat aaatttaagc gatcacgtaa gatagcatag
    23701 gctattttca tatcattagt tagattttta taattttcac tggtaaagaa tactttaggg
    23761 atttgataaa atctttcttt gtaattttct tgcactgtaa aatattgatt ttgcatgaca
    23821 aaaaacctct ttccatattt tagtttggta agaggtaata aaacgttttt atttagcttt
    23881 acatttattt aatgatttag gtgcttgcac taagatatta ttcattatat aatacaagta
    23941 tcgaaaatta tataaataaa cagtttctaa acgttttatt accaaacccc gactattacc
    24001 agtagttggg gtttttgtta tattaagttt attatagcac tttaaataaa cttataaaag
    24061 ggaaaatata actttatcaa gggtttataa acccttgata aatatcataa acctttcata
    24121 aacccttgat aaaaaggttg atggatgttt atttttattt attaatcact ttattattaa
    24181 gcattataag cttataatat tttatcaagg gtttataaac attttataaa gggttgatga
    24241 tatgaaaagt gtgaaaaagt tgagtgaaga attaggggtt agtaagcaaa cgatttttaa
    24301 taatattaag cgattgaata tagagacaat aaaacaggaa aacacttcgt ttattaaaga
    24361 agataccgat atagaaaaaa tcattcaaag agtaaatgaa aataaaaaga aatatggttt
    24421 tgaaagtact actgaagaca aacaaaaaaa agggtcggat aatattaatt ttgaatcgaa
    24481 aagcgatgct caaatagtag aaatccttaa aaatcagatt gatactttaa ataatcaaat
    24541 tgaaaaacaa gaaagtcgtc atgaaacaac aattgaattt tacagaaaag agttgcaaga
    24601 aagatcaaaa ttgcttgaaa atcagcaagt tctggcatta gagagtaata aaaagattca
    24661 aaaattagaa aatcaattag aaaaagaaaa acaccttaat tatccctttg atacatctac
    24721 taacactaga caaaacgttg atgcacaaga aaaaacatat actactaatc ctgtaaatat
    24781 taacagagat caggaagaaa ctaaagaaac agagattcaa tataaggata tatctggaag
    24841 tcaaagcgac gaaagtacac aaggtgaaga agcaaaaaaa gaagacgttc cagctaatct
    24901 aaatgacaat gatagtgata tagaagaaaa gagtgaagaa acggaaccta aaaaggggtt
    24961 ttggagtcgt ttgtttggta gctaaaataa ttgattaggc actaaaagtt ataaaatttt
    25021 agtgtctttt atatagtgag aacttctggt aatcatcgat tatgtaaact aaagtatttc
    25081 aaataattaa ctgtattaat actctcatca tgattgcgtt ataaacgttc gttattgaga
    25141 caaaatttaa tagtactact acacaaaaag agagtgcgaa ttcgcactct ctttttgtga
    25201 taaatgaatg gttaagaaaa taattcatcc acagttgtat caaacaatct tgccaactta
    25261 aatgctaatg tcaatgtagg atcatattta ttgttttcta ttgcattaat agtttgccta
    25321 gacactttta attctttact taaagtttct tgagaaattc ctttttgttt tctatattct
    25381 ctaattctat ttttcattaa tttaaccttt agatgtatat tttttatttg tagtatagta
    25441 attaaacagc ataagaaata gtgctacaat tataaagaaa atttctggat attgagaaaa
    25501 ccaagatcct tcaatacttg gtgacaaacc tgtaaattta agcactagtg taaataacat
    25561 acaatataca atccaaataa aacttttagc cagtatttca ataaacattt tacgttgtct
    25621 ttcatcgtat cgatcttgtt gtcctttttt atctaatgtt tctgaaggta aatatttgtt
    25681 agttatagcc gtccataaac aagaaaaaat taaaataata ataaaaggaa ttaaattcat
    25741 tataacacct cataaatgta aaaagtattt gacatttatg agtgtaaata tttttgatac
    25801 aaatgtcaaa tactttttac attataatat attttaaaac accttattag taaaacaatt
    25861 actatataga aagctgcgaa ctcgtactct tttttcttgt ataattatta aaatctcaat
    25921 tcaataatat gttatggaat ttgagacact gtgagagacg ctcatttgca ttgacaatca
    25981 atttatcaag ataatccctt atcatgttta attctataaa ctgtttgtct tgtgatatta
    26041 acttctttcg caatcttact aatcgctttg ccttcttcta acatttccac cacgcgatga
    26101 taaataacac gtttctgtgg gtctttagca tttggtgaat aaagtaaagg gcgcccttta
    26161 tatacgcctt tttccttcgc aacttgaatc ccttgcgctt gtcgacgttt actttcattt
    26221 ctctcttgtt ctgaaaccat tgctaatatt tgaatgatta aatctttcat aaacttatcc
    26281 agtaatggat tgccaattac ttcattcatc ataggtaagc tggtaatcat taactgaacg
    26341 tctttttctt ttaaataatt cacagtttca ataatttcat catagttacg tcctaaacga
    26401 tcaatagatt ccacaacgaa tcgatctccc attctgacaa aattgagtgc ttcttgaaat
    26461 acaggtctat tttccactga ctttcccgac tgtttctctg taaagatttt ctccacacca
    26521 aacgtcttta aattatccaa ttgtctttct aaattttgat ctatcgatga tactctcgca
    26581 taacctataa tcattcatct tcactccata ataaatatac accctaatca tacgttttaa
    26641 ttgttataat ttcaacaatt ctttttgtat ggttagggtg tactcaaagt gtacatatct
    26701 ataattaaaa cttactaaaa ataaatatag attttttctt tgtaacagaa ccgttcattt
    26761 gaaggtcatc tctatcataa atatttaaat taactaaaaa ttttaatcat ctgtttaata
    26821 cttatgaaat gtatttacgg taggtattaa aattgatgaa atttatataa gtgctttcaa
    26881 tgaaaatgac cgtttattta tcctcctgat ttaaggagtt agaaatttcg aaaacgattc
    26941 tttccatttg ttgcatttgt tccatgtcca gatatttaat acattataga aaaccaaaga
    27001 ccatcactaa ttaaacgcag ttttaaaatt tcatcaggat tgccttcgtc tttaaaatgg
    27061 gcctctt
//
