LOCUS       NC_010063              27041 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Staphylococcus aureus subsp. aureus USA300_TCH1516 plasmid
            pUSA300HOUMR, complete sequence.
ACCESSION   NC_010063
VERSION     NC_010063.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00253845
            Assembly: GCF_000017085.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus subsp. aureus USA300_TCH1516
  ORGANISM  Staphylococcus aureus subsp. aureus USA300_TCH1516
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27041)
  AUTHORS   Highlander,S.K., Hulten,K.G., Qin,X., Jiang,H., Yerrapragada,S.,
            Mason,E.O. Jr., Shang,Y., Williams,T.M., Fortunov,R.M., Liu,Y.,
            Igboeli,O., Petrosino,J., Tirumalai,M., Uzman,A., Fox,G.E.,
            Cardenas,A.M., Muzny,D.M., Hemphill,L., Ding,Y., Dugan,S.,
            Blyth,P.R., Buhay,C.J., Dinh,H.H., Hawes,A.C., Holder,M.,
            Kovar,C.L., Lee,S.L., Liu,W., Nazareth,L.V., Wang,Q., Zhou,J.,
            Kaplan,S.L. and Weinstock,G.M.
  TITLE     Subtle genetic changes enhance virulence of methicillin resistant
            and sensitive Staphylococcus aureus
  JOURNAL   BMC Microbiol 7, 99 (2007)
   PUBMED   17986343
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27041)
  AUTHORS   Highlander,S.K., Hulten,K.G., Qin,X., Jiang,H., Yerrapragada,S.,
            Mason,E.O., Shang,Y., Williams,T.M., Fortunov,R.M., Liu,Y.,
            Igboeli,O., Petrosino,J., Tirumalai,M., Uzman,A., Fox,G.E.,
            Cardenas,A.M., Muzny,D.M., Hemphill,L., Ding,Y., Dugan,S.,
            Blyth,P.R., Buhay,C.J., Dinh,H.H., Hawes,A.C., Holder,M.,
            Kovar,C.L., Lee,S.L., Liu,W., Nazareth,L.V., Wang,Q., Zhou,J.,
            Kaplan,S.L. and Weinstock,G.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2007) Molecular Virology and Microbiology and the
            Human Genome Sequencing Center, Baylor College of Medicine, One
            Baylor Plaza, Houston, TX 77030, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000017085.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 01:07:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,924
            CDSs (total)                      :: 2,845
            Genes (coding)                    :: 2,758
            CDSs (with protein)               :: 2,758
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 47 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 18 of 87
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000731.1.
            DNA and bacteria are available from: Sarah K. Highlander, Ph.D.,
            Associate Professor, Baylor College of Medicine, One Baylor Plaza,
            MS280, Houston, TX 77030, 713-798-6311
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27041
                     /organism="Staphylococcus aureus subsp. aureus
                     USA300_TCH1516"
                     /mol_type="genomic DNA"
                     /strain="USA300_TCH1516"
                     /sub_species="aureus"
                     /db_xref="taxon:451516"
                     /plasmid="pUSA300HOUMR"
                     /note="derived from methicillin-resistant clonal population
                     USA300"
     gene            232..1215
                     /locus_tag="USA300HOU_RS14730"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0001"
     CDS             232..1215
                     /locus_tag="USA300HOU_RS14730"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1235..1524
                     /locus_tag="USA300HOU_RS15640"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0002"
                     /pseudo=""
     CDS             <1235..1524
                     /locus_tag="USA300HOU_RS15640"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2071..2220
                     /locus_tag="USA300HOU_RS15935"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0003"
     CDS             2071..2220
                     /locus_tag="USA300HOU_RS15935"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695365.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQIHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(2388..3080)
                     /locus_tag="USA300HOU_RS14735"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0004"
     CDS             complement(2388..3080)
                     /locus_tag="USA300HOU_RS14735"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            3190..3384
                     /locus_tag="USA300HOU_RS14740"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0005"
     CDS             3190..3384
                     /locus_tag="USA300HOU_RS14740"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4500..5117
                     /gene="cadD"
                     /locus_tag="USA300HOU_RS14745"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0007"
     ARG             4501..5114
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5136..5483
                     /locus_tag="USA300HOU_RS14750"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0008"
     CDS             5136..5483
                     /locus_tag="USA300HOU_RS14750"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5640..5732
                     /locus_tag="USA300HOU_RS15870"
     CDS             5640..5732
                     /locus_tag="USA300HOU_RS15870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5904..6847)
                     /locus_tag="USA300HOU_RS14755"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0009"
                     /pseudo=""
     CDS             complement(5904..6847)
                     /locus_tag="USA300HOU_RS14755"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /name="oxidoreductase"
     gene            6971..7390
                     /locus_tag="USA300HOU_RS14760"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0010"
     CDS             6971..7390
                     /locus_tag="USA300HOU_RS14760"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7916..8761)
                     /gene="blaZ"
                     /locus_tag="USA300HOU_RS14765"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0011"
     ARG             complement(7920..8761)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8868..10625
                     /gene="blaR1"
                     /locus_tag="USA300HOU_RS14770"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0012"
     ARG             8869..10622
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10615..10995
                     /gene="blaI"
                     /locus_tag="USA300HOU_RS14775"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0013"
     ARG             10616..10992
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11259..11837
                     /locus_tag="USA300HOU_RS14780"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0014"
     CDS             11259..11837
                     /locus_tag="USA300HOU_RS14780"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(12060..12245)
                     /locus_tag="USA300HOU_RS14785"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0015"
     CDS             complement(12060..12245)
                     /locus_tag="USA300HOU_RS14785"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            12507..13181
                     /locus_tag="USA300HOU_RS14790"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0016"
     CDS             12507..13181
                     /locus_tag="USA300HOU_RS14790"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13350..13921)
                     /locus_tag="USA300HOU_RS15650"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0017"
                     /pseudo=""
     CDS             complement(13350..13921)
                     /locus_tag="USA300HOU_RS15650"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(14197..14991)
                     /gene="aph(3')-IIIa"
                     /locus_tag="USA300HOU_RS14800"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0018"
     ARG             complement(14201..14991)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15084..15614)
                     /gene="sat4"
                     /locus_tag="USA300HOU_RS14805"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0019"
     ARG             complement(15088..15614)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15611..>16246)
                     /locus_tag="USA300HOU_RS15660"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0020"
                     /pseudo=""
     CDS             complement(15611..>16246)
                     /locus_tag="USA300HOU_RS15660"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16387..17061)
                     /locus_tag="USA300HOU_RS14820"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0021"
     CDS             complement(16387..17061)
                     /locus_tag="USA300HOU_RS14820"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<17118..17294)
                     /locus_tag="USA300HOU_RS14825"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0022"
                     /pseudo=""
     CDS             complement(<17118..17294)
                     /locus_tag="USA300HOU_RS14825"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17308..18045)
                     /locus_tag="USA300HOU_RS14830"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0023"
     CDS             complement(17308..18045)
                     /locus_tag="USA300HOU_RS14830"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(18038..18967)
                     /locus_tag="USA300HOU_RS14835"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0024"
     CDS             complement(18038..18967)
                     /locus_tag="USA300HOU_RS14835"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(19083..19964)
                     /locus_tag="USA300HOU_RS14840"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0025"
                     /pseudo=""
     CDS             complement(19083..19964)
                     /locus_tag="USA300HOU_RS14840"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19961..>20338)
                     /locus_tag="USA300HOU_RS14850"
                     /pseudo=""
     CDS             complement(19961..>20338)
                     /locus_tag="USA300HOU_RS14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20396..21070)
                     /locus_tag="USA300HOU_RS14855"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0027"
     CDS             complement(20396..21070)
                     /locus_tag="USA300HOU_RS14855"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21544..23010
                     /gene="msr(A)"
                     /locus_tag="USA300HOU_RS14860"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0028"
     ARG             21545..23007
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            23109..24008
                     /locus_tag="USA300HOU_RS14865"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0029"
     CDS             23109..24008
                     /locus_tag="USA300HOU_RS14865"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24494..25102
                     /locus_tag="USA300HOU_RS14870"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0030"
     CDS             24494..25102
                     /locus_tag="USA300HOU_RS14870"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25348..25687
                     /locus_tag="USA300HOU_RS14875"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0031"
                     /pseudo=""
     CDS             25348..25687
                     /locus_tag="USA300HOU_RS14875"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            25692..25877
                     /locus_tag="USA300HOU_RS14880"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0032"
     CDS             25692..25877
                     /locus_tag="USA300HOU_RS14880"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(26104..26847)
                     /locus_tag="USA300HOU_RS14885"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0033"
     CDS             complement(26104..26847)
                     /locus_tag="USA300HOU_RS14885"
                     /old_locus_tag="USA300HOU_pUSA300HOUMR0033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             23110..24005
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21545..23010
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             23110..24008
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(15085..15602)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15909..16210)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7917..8761)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1581..1728
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          233..1215
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1347..1516
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(26105..26847)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atttaaagtg ctataataaa cttaatataa caaaaacccc aactactggt aatagtcggg
       61 gtttggtaat aaaacgttta raaactgttt atttatataa ttttcgatac ttgtattata
      121 taatgaataa tatcttagtg caagcaccta aatcattaaa taaatgtaaa gctaaataaa
      181 aacgttttat tacctcttac caaactaaaa tatggaaaga ggttttttgt catgcaaaat
      241 caatatttta cagtgcaaga aaattacaaa gaaagatttt atcaaatccc taaagtattc
      301 tttaccagtg aaaattataa aaatctaact aatgatatga aaatagccta tgctatctta
      361 cgtgatcgct taaatttatc tattaaaaat agctgggttg atgaagatgg taacatttac
      421 tttgtttatt caaatgaaaa gctaatggaa atcttaaatt gtaaaaaaga aaagttaaca
      481 aaaataaaaa aagggttaga aaacgatggt ctactcattc aaaaacgacg tggtttaaat
      541 aaaccaaata ttctatattt aatgaaacct attgtcacag aacgtgatat ttacaaaata
      601 gaaaaagaag aaaacgatgt tgaaccttac ggcgagaagg aagttcgaaa atcgaacgtc
      661 cagaagttcg aaaatcgaac gtccagaagt tcgaaaatcg aacgtccaga agttcgaaaa
      721 tcgaacacta atgatactga ctttaatgac attgacttta atgatactga gaataatgat
      781 atgaatgact tgaatgatat aaagtacaaa aatgaaatta gtaatcattc aaatcattca
      841 aatcaattta cacataattt tgatgataaa gaaatgctat tgcaagaatt cccagaacaa
      901 ctaactaatt atttattaaa atatgattat agagatttag aaatcataaa ggctgttatt
      961 cttaaagcaa aaaaatcatt taattcaagg catgaagata tgcattacat gttagaggac
     1021 attgaggatg aaatattaac ttctttaaaa agacttaaaa aagctataca tgatagggga
     1081 gttaaaggcc aaaaggaaac aatcaagtca atgcaagctt atttaatgca aacaattcta
     1141 actgaacttg aagaaacaca tgccctttat atgcgccgta aaaacatgaa acaatataat
     1201 atctttaatc aataattcaa atgattttat aacactcgaa gagacatcaa aatattccgt
     1261 taaatcatct gactttttaa ctgatgacga cgaaaaaaat caagaaattg taagtgattt
     1321 agaaaaaggt ttgtatcgaa aacgtatgtt aagttatggt ggattgctta aacaaaagca
     1381 taaaatttta aacttagacg atgccgaaga tggtaatttg attaatacaa gtgatgaaga
     1441 taaaacgaca gacgaagaaa aaaagcacat tcaattaccg caatttggaa tttcgaaaag
     1501 caaaattatt atttaagaca ttagtgataa ctgatgtctt tttttattgt ttttctgtaa
     1561 aaaagtgctg tcttattttt gtgacaaatg ctgtatgtag tgtcacaaaa gtgtgacact
     1621 acagctttgt atgatatcac tttaaaataa cttaaaaccc ttggaatgtc tggccttgcc
     1681 agatctatca tttttgaatg atagcaaatt tcccttatgc tcttacggag attttagagt
     1741 taaattaaaa tttctaagtt tttgataaga aaagccctgc aggaatttag aaaaacatgg
     1801 ggaagtttta aagtatttta tgctaatttt taaatttgca tgtaaatggg cagtatctaa
     1861 aaaattagtc actgattttg ctgaaatttt tgtttgtgaa attagcatat atttatttgg
     1921 ctcatatttg cgttttaaga gactgtatag atttttaagt acaaaaccta tatgatttgc
     1981 ctctaagtct tcaaaatgcc tcttaaaatc caaaataaaa gtgtttaata ttgtaataag
     2041 gattgctatt tttataaaag gagagatatc atgaagatta aaactttcgc tacttttact
     2101 catcgtcaat tagataaaca agttaatagg tttttaaaga atgatattca tgtattagaa
     2161 attcaaatac acagtaattg gttatatatt tcagctattg ttttttatga ggataaataa
     2221 ggaacatcgt atttatgccg aaaaaattta ttgatgttga gaagaaccct taactaaact
     2281 tgcagacgaa tgtcggcata gcgtgagcta ttaagccgac cattcgacaa gttttgggat
     2341 tgttaagggt tccgaggctc aacgtcaata aaacaattgg aataaaatca acctacagag
     2401 catccagctg caaatgcagt tccgcaaact gcttcacata caccgccggc tattggattt
     2461 acgattgccc atactccaca gtagtgagca catgcataaa gtccagccat actacaagcg
     2521 aatgctttgc cgttccattt gaatcctgca tatgttaccg gtctgttttt atcaactttt
     2581 tcagccttat attcaacgta atttttgtta ataagtattt ttccctcttt gttttcagtc
     2641 atacttcttt tttcggcaat gaattttgtg atttttttgt tgtagttatc atatattgtt
     2701 tcagaaacta caatttcttt tgttttttca tttttataag cgttattagc tatgtagcca
     2761 tatgcatttt tatcatttgc ttctgtagct agatatttta atttagaatt tttgtcttct
     2821 agctttattt ttttaaatcc ttcttttttc atttgctttt cgaatttttg catatcttca
     2881 tttttatttt gcaattgttc tagaaaactt atttctttct tggtcatttg tgatacttcg
     2941 atgtttttgc ttttcaattt ttctttttga ttttctagta aagaactttt ttgttcttca
     3001 tttgcgtaag cattagaaaa attcgcgcta aataccagta ggaacaagga aattattgaa
     3061 aataatttta taattttcat ttgatacctc caagataata agatatttta attgtataag
     3121 taagcgcttt ataaaatcaa tatttatttt aatatattta taaacatatt tttgaaagga
     3181 gtctatttta tgaatgaaaa tttagaaaaa tatataaaaa gtttgccact tttaggtttg
     3241 ttaattagta ttttgttaat tgttttattc ttttttattt tagatgttga tgaagattta
     3301 ttcgtggttt ttttatactg tttattgcct ttgatagtta atttgtctat ttatggtttt
     3361 tatgtttttg ttaaaagaaa gtaagattat gaataatttt gtttttaatt tgtatgcttt
     3421 gagggggttg gaaaacggta ggtgtataga ttagatttct tgtttttttg aaacgagtgt
     3481 gaacgagttt cttcttgtct tgatttttga taaaaacgcc ctacaggaat ttagaaaaac
     3541 gtggggaagt tttaaagaat tttatgctaa tttttaattt gcatgtaaat gggcagtgtc
     3601 taaaaatagt tattgttttt gctcaaattt ttgtttttga aaatagcata tatttatttg
     3661 gctcatattt gcgttttaaa agcatatata agttttagat ataaaactat atgaatcacc
     3721 cctaaatctt taaaatgccc tcttaaaatt caaaataagg gcataaaaaa taaaagctac
     3781 cccagataaa gtgaggtagc tttttctttc atacggtcta tttatttttc tttcgacgcc
     3841 gtatcgtcga tgtaattcaa aaaagttatg ggctataaat ctacatcact ttttcaagaa
     3901 tgtagtagca atattcaacg caaattaatt tttataactg ctcggaatat ctcaagccgt
     3961 ttctttaatt ttgaaataaa aaaatcgacg aaggtcgatt acgtttttgc acatgtcgat
     4021 ttatccgacg tataagtgcg cccttacggg atttaactag attataacga cgaattttag
     4081 acctgtaaag caataacaat taggtctacc aggtagataa agtgtacaaa gtagaaccga
     4141 aaaagttatt tattttgaag atttttcgta gatataattt gctaataaac ttcctaaaac
     4201 tgaataaaga aaaatagtta aactcatgta atcactccat aattctgaag tgtctccatg
     4261 tctacgcata gacacgcatt tatgccgaaa aaatttattg atgttgagaa gaacccttaa
     4321 ctaaacttgc agacgaatgt cggcatagcg tgagctatta agccgaccat tcgacaagtt
     4381 ttgggattgt taagggttcc gaggctcaac gtcaataaag caattggaat aaagcaccta
     4441 tgattattta aaaatataag ttataataca ttcaaaaata tttttgaatg aggtgtatta
     4501 tgattcaaac ggttgttgct gctgctgttc tttatattgc tacagcagtt gatttattag
     4561 taattttatt aatatttttt gctagagcaa agactagaaa agaatataga gatatttatg
     4621 ttggtcaata tttagggtct attattttaa tattagttag tttgttttta gcttttgtat
     4681 taaattatgt tccagaaaag tggatattag gtttattggg tttaatacca atttatcttg
     4741 gaattaaagt ggctatttat gatgattgtg aaggagaaaa gagagctaaa aaagaattga
     4801 atgaaaaagg attgtctaaa ttagttggta cggttgcaat tgttacgata gcaagttgtg
     4861 gcgccgataa tattggttta tttgttccgt attttgtgac attaagtgtt actaatttat
     4921 tacttactct gtttgtcttt ttaattttaa ttttcttctt ggtgtttact gcacaaaaat
     4981 tagctaatat tccaggaatt ggagaaattg ttgagaaatt tagtcgttgg attatggcta
     5041 ttatttatat agctttaggt ttatttatta ttattgaaaa tgacactatt caaacaattt
     5101 taggatttat attttaattt agggtgtgat tttatatgag ttatgaaaat acttgtgatg
     5161 tgatctgtgt acatgaggat aaagttaaca atgctttaag ttttttagaa gatgataaat
     5221 ctaagaaatt acttaacatt ttagaaaaaa tttgtgatga gaagaaattg aaaatcatat
     5281 tatctttgat taaagaagat gagttgtgtg tttgtgatat ttctttgata ttgaaaatga
     5341 gtgttgcttc aacttcacat catttaaggc ttttatataa aaatgaggta cttgattttt
     5401 ataaagatgg aaagatggca tattatttta ttaaagacga tgaaataaga gagtttttct
     5461 ctaaaaatca tgagggtttt tgaaacgagt ttcttcttgt cttgatacta taaaaaacaa
     5521 agttatataa cataagacga cttatcggaa gtagatatgc ttgtatattc acagatggta
     5581 taataataga gtcgcctatc tctcaggcgt caattgacga agagaggagg tgcattactt
     5641 tgctaatcat tttcgttcac atcatagcac cagtcatcag tggctgtgct gttgcgtatt
     5701 atacttattg gcttagtaaa cgcaacaaat aattaatagg cgactttata agccagcatc
     5761 gaaaaaatcc ccacactact gcaatagtgt ggggattggt gcattaattg ttaatcattt
     5821 tcgttatata aattataaca ctggttagta gagaaatgca aaatgattga attaatagta
     5881 aatgtattaa tgaatactca cacttatact tttaaaatag ttcttcctaa atgttgtcct
     5941 tttaaaagct gatctatcgt tttatagaat tcttcaaatc caatttcatt gtatagaagt
     6001 gaatttccta tattccattc atttgctaac ttactccata tatcttcacg gatattatga
     6061 tcaacatata cagaatcaat gccaattaat ttaatacctc taagaataaa cggtaatata
     6121 ttagcgttaa gtgaatttcc tgctacattt ccacatacag tagcaacacc ttgataattt
     6181 agacgtttta aaccgtataa tgttacatta ctccccactg tatctaagaa ataatcaaaa
     6241 ataccttttt taagcggttt attatcatct tcaattatta ttacttgttt tgcacctaat
     6301 ttttttgcga tttctatttg cttttctttt cttacgatag cagtgatatt ttcatatcca
     6361 attttatgta aaatttgtat agcaacactg cccacaccac ctgtagcccc agacactaaa
     6421 atttcaggtt gtgatttgat attcattcca tatttttcta gttcaaaaat tgataatgct
     6481 gccgtaaaac cggctgtgcc atataccata gactctttaa tagacatttc ttggggaata
     6541 ggaacaatcc acatccacct gtatgtgtca cgccaacatc ataaccagta actaatacat
     6601 tatcgccttc tttaaactta tcattcgaac ttgattcaac aatacctgca aaatctatac
     6661 caggaatcat aggataatct ctaattacac cgcctttata ttgtaaagct agcatatcct
     6721 tataatttat tgaagagtat accactttta ctaatacatc acccttcgat aaatgagatt
     6781 catcaacttt ttctacttta taactaacat ttgatgcact ttttctcact actaccgcat
     6841 tgaacattta ttagccttct ttcacaattg ttttgtagaa gtatgttttt gttgcaaaac
     6901 tattttccta caaaacttat catgatatga taagcgagtc aatactaatg atttaagaga
     6961 ggttttagtt gtggaattag ataattgtat aaattatttg ttgagtactt ctcagaatag
     7021 agtttttaaa cattttaaaa gtttattaag tccctataat attactccag cagaatatgg
     7081 tgttttgaat tgcttgatta atagtaattt gaatacacct aaagcgattg gtaatacttt
     7141 aaatttagaa ccttcaacaa tatctggaat attagataag atgtccaaaa aggatctaat
     7201 aacacgtcaa actgataatg aaaatagaag aactgtgcta ataaacagta caaataaagc
     7261 aaaagactta tggccaacat tagaaaagaa agcctatcaa cttaataatc attacttcgc
     7321 taatttaact aatgaagaaa ctgtagtgtt taaaaagata ttactaaaga taaataaaac
     7381 tacgttttaa tttttacgtt ataaaaaagt tgaagtgcga attataatcg agtaaatata
     7441 aatgatagct tagcttaatt atatattaaa gccaactata cttttattcc cgaaaaacct
     7501 actatccaaa tttctaagat actttagcct ctataataaa catattgtaa tataatttat
     7561 gtattattta ggtttaccct aatcgaacaa taaaaaatac ttgtaaaatg ctattgtcac
     7621 tttgcttgat atatgagaat tatttaacct tataaatgag aaaaaagcaa cgcactttaa
     7681 ataagatacg ttgctttttc gattgatgaa cacctataat taaactattc atctattatt
     7741 tatgattttt tgtatataca atatttctag tttgttaaag agaattaaga aaataaatct
     7801 cgaaaataat aaagggaaaa tcagtttttg atatcaaaat tatacatgtc aacgataata
     7861 caaaatataa tacaaactat aagatgttat cagtatttat tatgcattta gaatattaaa
     7921 attccttcat tacactcttg gcggtttcac ttatcaactt atcatttggc ttatcacttt
     7981 tattgtcttt attcgtaaaa atgactaaaa caataggttc agattggccc ttaggataaa
     8041 caaaagcaac atcatttcta gaagcatatg ttattgcttg accactttta tcagcaacct
     8101 tatagtcttt tggaacacca tctttaatta aagtgtctcc gtttttatta ttaaacatta
     8161 aatcaagtaa gaaattttta ttttttttgc ttaattttcc atttgcgata agtttattta
     8221 aagtcttgcc gaaagcagca ggcgttgaag tatctttttt gctctttggt gaatagtaat
     8281 ttaattctat ctcatatcta actggatttg ttactttatc tcctagttct tttagacgtt
     8341 gtttaacttt tttgattcca ccgatttctt ttataatttt attgtttgct gtattatcac
     8401 tatatgtcat tgaagcctca ataagttctt ttaaagtgat atcttttcct acatattttt
     8461 ctaaaatagg agaataagca actatatcat ctttgttaat atgtactttt ttatttaact
     8521 tattataagg tacttgttct aacaaaatag cactatttat cgcttttgaa gtcgaagcat
     8581 aggcaaatct cttatctgaa ttaaatttta cttccttacc acttttagta tttaaagcat
     8641 aaacaccaat atgagcatta tatttttttt ctaaatcatt taactctttg gcatgtgaac
     8701 tgtttgaatt acatgcactt aaaactaaag caattacaat taaaaatatt aactttttca
     8761 aaataaaccc tccgatatta cagttgtaat ttttataaat caataatatt acaattgtaa
     8821 tattgatgtc aattgtttat tataaatatt tgaaagaagg tgtcaaaatg gctaaattac
     8881 taataatgag cgtagtaagc ttttgtttta tatttctatt gttagtattt tttaggtaca
     8941 tattaaaacg ctattttaat tatagtttaa attataaagt ttggtatcta actatgcttg
     9001 ctggattaat tccttttatc ccaattaaat tctcttttat aaaatttaat aatgtgaata
     9061 atcaagcgcc cacagttgaa agtaagtcac acgatttgaa ccataacata aataccacca
     9121 aacctattca agagttcaca acagatatcc ataagtttaa ttgggattca attgataata
     9181 tctgcacagt tatttggata gttttagtta ttattttaag ttttaaattt ttgaaagcct
     9241 tattatatct taaatattta aagaaacagt cactttatct aaacgaaaat gaaaaaaata
     9301 aaatagatac gatacttttc aaccatcaat ataaaaaaaa tattgtgatt cgaaaagcag
     9361 aggctattca atctccaata actttttggt atgggaaata tattattttg attcctagtt
     9421 catattttaa aagtgtaatt gataaaagac taaaatatat aatactgcat gaatatgctc
     9481 atgctaaaaa tagagatact ttacatttaa ttatctttaa tatcttctct attattatga
     9541 gttacaatcc attagtacat attgtaaaaa gaaagataat tcatgacaat gaagtagaag
     9601 ccgatagatt tgtccttaat aatattaaca aaaatgaatt taaaacttat gcggaatcta
     9661 ttatggactc cgtattaaaa accccatttt ccaacaaaaa tatattaagc cattcattta
     9721 atggtaaaaa atcattactc aaaagtagat taattaatat aaaagaagcc gatctgaaaa
     9781 agcagtcaaa attaattcta atttttattt gtatttttac tttttttatc atgataattc
     9841 aaagccagtt tttaatgggg caatccttaa ctgattataa ttataaaaag cccttacaaa
     9901 gcgattacca aattttagat gaaagtaaaa attttggttc aaatagtgga tctttcgtta
     9961 tgtacagcat gaagaaagac aaatactata tttataatga aaaagaaagt agaaaaagat
    10021 attctcctga ttcaacttac aaaatttatt tagcactgtt tggacttgac cgtcatatta
    10081 taagtgataa aaattcacgt atgtcatgga atcataaaca ttatcttttc gagtcttgga
    10141 ataaggaaca agatttaaat acagcaatgc aaaattcagt taattggtac ttcgaacgta
    10201 ttagtaatca aataccaaag aactatactg cggctcaact caagcaatta aattatggta
    10261 atgaaaattt gggaagttat aaaagctatt ggatggaaga tagtttgaaa atatctaatc
    10321 ttgaacaagt aatagttttt aaaaatatga tggaacaaaa taaccatttt agtaaaaaag
    10381 caaagaatca attatcttct tcattattga ttaagaaaaa tgaaaagtat gaactgtatg
    10441 ggaaaacagg tacaggtata gtaaacggga agtataataa tgggtggttt gtaggttacg
    10501 taattacaaa tcatgataag tattattttg ctacacattt atcagatgga aacccgtctg
    10561 ggaaaaatgc tgaattaata agtgaaaaaa tattaaaagg aatgggtgtt ttaaatgacc
    10621 aataagcaag ttgaaatatc tatggctgaa tgggatgtta tgaatataat atgggataaa
    10681 aaatcagtat cagctaatga aattgtagtt gaaattcaaa aatataaaga agttagtgat
    10741 aaaacgatta gaacattaat cacaagacta tataaaaaag agattataaa acgatacaaa
    10801 tcagaaaata tttattttta ctcatcaaat attaaagaag acgatattaa aatgaaaact
    10861 gctaaaacct ttcttaataa actgtatgga ggggatatga aaagtttagt gctgaatttt
    10921 gcgaaaaatg aagaattaaa taacaaagaa attgaagaat tgcgagacat tttaaatgat
    10981 attagtaaaa agtaattaga ggtatgtttc aaacataata catatgtaaa ccatacttga
    11041 ctcttattaa attagttttg ttaatgacat ttaaaatata ttattaaaga tgagagtgtc
    11101 cagaaaataa ccattttctg tacactcttg ttttttgtct aaataagtaa gtattacata
    11161 gaattatgtg ttcaaaaacc caacaaaaaa tctatgttca caaaagacct cgtaatcaag
    11221 ttatggtaca ctaaaggtgt atataggagg tctgtatttt gaaaataggt tatgcaagag
    11281 tttcaactgg attacaaaat ttgaatttac aggaggatcg attaaataca tatggttgtg
    11341 aaaagatatt taatgaccat atgagtggtt caaaaagtaa gcgacctggt ttagataaag
    11401 caattgaatt tgcgaggtca ggagatacga ttgttgtttg gagattagat agactaggac
    11461 ggaacatgga ggatttaatc acgttagtta atgaacttaa cgaacgaggt gtgagttttc
    11521 atagtttaga agaaaatata acgatggata aatcaagttc tacaggacaa ttattatttc
    11581 atttattcgc agcatttgca gagtttgaac gtaatttaat tttagagcga tcatcagccg
    11641 gtcgaattgc agcacgtgct agaggccgat atggaggtag acctgaaaaa ttaaataaac
    11701 aagatttaaa cttacttaag acactttatg ataatggtac gccaattaaa acaattgcag
    11761 agcagtggca agtttcacgt acaactattt atcgttatct caataaatta gaggcaaaag
    11821 agaataaaaa caagtagagc aactaatcta gcttactata atgaatctac taaataattt
    11881 tatatatcat taacatacaa agactttgat tcaatgtcac tcgatgtaaa agagacgttc
    11941 tgacagcgtc taaaatctca taatattttc ctgttatgag attttaataa taacacaaga
    12001 aaaaagcgta caaattcgta cgctttttta atataatacc tgtttcacta atgaacgttt
    12061 taagtatctt catcattaac tgaaactaca gtaataatac tcgtcaacaa tattagtata
    12121 gttaaaatag aaagacttag gactggcata accgaactaa aattatattt gaaatataaa
    12181 agtgctaatg aagagagaaa tgtaaaaata ataaatacca aagaccattt ttctaattta
    12241 ttcattggct tcacctcttt gaacttttat ataatcatag gagatatttt tactacgatt
    12301 tataaaaaat aagaagataa tcattattaa agaaacgatt aatataatgt tgaatcctat
    12361 agtatcacct aattcgttta cacctttgcc taatatcgga gatacaaagc tttgtattaa
    12421 taatgaaaga gatgcccata tagtaaatga ggttctgttg caaagttgaa tttatagtat
    12481 aattttaaca aaaaggagtc ttctgtatga actatttcag atataaacaa tttaacaagg
    12541 atgttatcac tgtagctgtt ggctactatc taagatatgc attgagttat cgtgatatat
    12601 ctgaaatatt aagggaacgt ggtgtaaacg ttcatcattc aacggtctac cgttgggttc
    12661 aagaatatgc cccaatttta tatcaaattt ggaagaaaaa gcataaaaaa gcttattaca
    12721 aatggcgtat tgatgagacg tacatcaaaa taaaaggaaa atggagctat ttatatcgtg
    12781 ccattgatgc agagggacat acattagata tttggttgcg taagcaacga gataatcatt
    12841 cagcatatgc gtttatcaaa cgtctcatta aacaatttgg taaacctcaa aaggtaatta
    12901 cagatcaggc accttcaacg aaggtagcaa tggttaaagt aattaaagct tttaaactta
    12961 aacctgactg ccattgtaca tcgaaatatc tgaataacct cattgagcaa gatcaccgtc
    13021 atattaaagt aagaaagaca aggtatcaaa gtatcaatac agcaaagaat actttaaaag
    13081 gtattgagtg tatttacgct ctatataaaa agaaccgcag gtctcttcag atctacggat
    13141 tttcgccatg ccacgaaatt agcatcatgc tagcaagtta agcgaacact gacatgataa
    13201 attagtggtt agctatattt ttttactttg caacagaacc agcatttgtt ttaatatttg
    13261 ttccaaagag ccatcatggc tttgacagag ctcttcttct atgcaaatgc ttttaatccg
    13321 atccacacga aaattcctat attcatttct tagcctgcaa aaccgattaa gtaccagttc
    13381 tgttcataaa accccagtga tataggctct atcattctgc tttccggttc ttgccctcct
    13441 gatgcaggat attgaattga tattaccctt ttattgcaga ttgcagtctg aattgctgca
    13501 ataacgttat ccgccaatgt atttttctgt ccagatgtgc tgtacacgtt aatactgttc
    13561 tccaactcct gtgcatagtt tttttcacca tgcttcaaaa tagatttgat tttatacata
    13621 gctgaatcaa aatcctttat aaatgattca tctccatggc aatttaaaaa tttccctgct
    13681 gtaatcaatg cacccacttc cgccgctgta aacattaccg gcagaagtag gaagccctct
    13741 acaagaaaat atccttttcc ggcctcagat ccaattggta ttccggcttc ttcaagtgtc
    13801 cggatatctc tgtaaactgt ccttaagctt atattaaatc gctgtgcaat ttctttggca
    13861 ggaattattt ttttgattgc agctgaataa gaatagaggt tactctgtta atcctgttca
    13921 aattttattc ctcctctgtg acttccataa aaagtatatc ctatgcgttc ttaagctagc
    13981 tgctgttagt gcttctcatt gcaccctggt tataaaagcc atactcacaa acctcttcac
    14041 caaaactctt tacatctcta atatagaact ctatctagcg aacttttaga aaagatataa
    14101 aacatcagag tatggacagt tgcggatgta cttcagaaaa gattagatgt ctaaaaagct
    14161 tgtagttaaa gctttttaga catctaaatc taggtactaa aacaattcat ccagtaaaat
    14221 ataatatttt attttctccc aatcaggctt gatccccagt aagtcaaaaa atagctcgac
    14281 atactgttct tccccgatat cctccctgat cgaccggacg cagaaggcaa tgtcatacca
    14341 cttgtccgcc ctgccgcttc tcccaagatc aataaagcca cttactttgc catctttcac
    14401 aaagatgttg ctgtctccca ggtcgccgtg ggaaaagaca agttcctctt cgggcttttc
    14461 cgtctttaaa aaatcataca gctcgcgcgg atctttaaat ggagtgtctt cttcccagtt
    14521 ttcgcaatcc acatcggcca gatcgttatt cagtaagtaa tccaattcgg ctaagcggct
    14581 gtctaagcta ttcgtatagg gacaatccga tatgtcgatg gagtgaaaga gcctgatgca
    14641 ctccgcatac agctcgataa tcttttcagg gctttgttca tcttcatact cttccgagca
    14701 aaggacgcca tcggcctcac tcatgagcag attgctccag ccatcatgcc gttcaaagtg
    14761 caggaccttt ggaacaggca gctttccttc cagccatagc atcatgtcct tttcccgttc
    14821 cacatcatag gtggtccctt tataccggct gtccgtcatt tttaaatata ggttttcatt
    14881 ttctcccacc agcttatata ccttagcagg agacattcct tccgtatctt ttacgcagcg
    14941 gtatttttcg atcagttttt tcaattccgg tgatattctc attttagcca tttattattt
    15001 ccttcctctt ttctacagta tttaaagata ccccaagaag ctaattataa caagacgaac
    15061 tccaattcac tgttccttgc attctaaaac cttaaatacc agaaaacagc tttttcaaag
    15121 ttggcgtata acatagtatc gacggagccg attttgaaac cacaattatg atagaattta
    15181 caagctataa ggttattgtc ctgggtttca agcattagtc catgcaagtt tttatgcttt
    15241 gcccattcta tagatatatt gataagcgcg ctgcctatgc cttgccccct gaaatcctta
    15301 catacggcga tatcttctat ataagcgtac cggttccaat tttttcgcag tttaactttt
    15361 ccgacgcatt tatcgtcttg gtagtaaaga tatattatct tatcagtatt gtcaatatat
    15421 tcaaggcaat ctgcctcctc atcctcttca tcctcttcgt cttggtagct ttttaaatat
    15481 ggcgcttcat agagtaattc tgtaaaggtc caattctcgt tttcatacct cggtataatc
    15541 ttacctatca cctcaaatgg ttcgctgggt ttatcgatat ctttcaggtg ccctgctttc
    15601 atttctgtaa tcactgttcc cgcctctctt ctatatcagc ggcatatgtg ctatccaggc
    15661 agccggtttt accagtgtat tttttataca tgtccctggt atattttgtt atattcctat
    15721 catactccgg ataggcataa tgaagccttt ccgccacctc accggatacc gccctgaaca
    15781 attgatggca tagaaataat gcttcccata tgttttcata ggaatccatc cggtaggtgg
    15841 acaaaagttt ctcccacaaa tcctcggata tatacctttc aataaactta tagttcttgc
    15901 ctacacttca tttaaagcct gtttcgatgc cgaccttcca tgatatcatt ctcagcagct
    15961 catggcgaac aatctgatta aaatgatcaa tagcaaataa aatttcctta cggcacaatc
    16021 ctttaataac ataaggtgtt acattccaaa attcattgca gcaatcatca tactcccttg
    16081 cgcttggctt tcttacatga taatctatat cagtcggaac tatgtccctt ttaattctac
    16141 aatctttatc aattagaacc tttattaatt tatcgccctt taggtaatta tctaactctt
    16201 ccaagggcaa taaggtaaga tcaattttat tgtaatcatc aaatagctat aatagattta
    16261 gaggtaaaga aattaaatac attgaagagc agaaagattt tacaaaagag tattttaata
    16321 aaaatgatgg ttctgttgca aagtaaaaaa tatagctaat cactaatata tcatgtcagt
    16381 gttcgtttaa cttgctagca tgatgctaat ttcgtggcat ggcgaaaatc cgtagatctg
    16441 aagagacctg cggttctttt tatatagagc gtaaatacac tcaatacctt ttaaagtatt
    16501 ctttgctgta ttgatacttt gataccttgt ctttcttact ttaatatgac ggtgatcttg
    16561 ctcaatgagg ttattcagat atttcgatgt acaatggcag tcaggtttaa gtttaaaagc
    16621 tttaattact ttaaccattg ctaccttcgt tgaaggtgcc tgatctgtaa ttaccttttg
    16681 aggtttacca aattgtttaa tgagacgttt gataaacgca tatgctgaat gattatctcg
    16741 ttgcttacgc aaccaaatat ctaatgtatg tccctctgta tcaatggcac gatataaata
    16801 gctccatttt ccttttattt tgatatacgt ctcatcaata cgccatttgt aataagcttt
    16861 tttatgcttt ttcttccaaa tttgatataa aattggggca tattcttgaa cccaacggta
    16921 gatcgttgaa tgatgaacgt ttacaccacg ttctcttaat atttcagata tatcacgata
    16981 gctcaatgca tatcttagat agtagccaac ggctacagtg ataacatcct tgttaaattg
    17041 tttatatctg aaatagttca tacagaagac tcctttttgt taaaattata ttataaattc
    17101 aactttgcaa cagaacctcc taactgtatt accaccttaa aagtagttgc agacgcactt
    17161 cctaaatcgt cagcagtgtt taaccacata tcatcaacaa taatcatatg acctgttgat
    17221 gatactggag caaattctgt caacccttca actacaccta aaataaatgc tttaatctgc
    17281 tctataaaac ccatttttct cctcctttta acttatatca gtttttttaa agtatgagaa
    17341 taatataatt acactgaata tagatgtaac aattatgata attaaagata atagaaatgg
    17401 ataagtatta ggtaatgttc ctctagatat gtctccaact gcagcccaag gaaataatcc
    17461 tctatgttca gaattagcag tcattaaatt tatcaaagta attattatgg ttaaaacaat
    17521 tgtgggaaca taatttttaa aatatatcga caaaataatt attggtggag ataatatcca
    17581 taataacact ccgccaataa caaatgtaaa gaatgaatca attattaaac tctggcttaa
    17641 cccttgaaaa tgcaatagca tacctagcat taaagttagc aaccatgcaa taacagatag
    17701 tgtttgaatc cacaagaata ataatattat tttacttact aaaaaacttt ctctagatat
    17761 aggtataatt aataagtttt ttaaagtatc ttctatatat tctcttccaa acaaataggc
    17821 tattataacc ccatatagag gaggtccaat aattagcata tgatataaac tgacttcttc
    17881 aaataactgt ttaaatacaa tattaggagt cggtactttc gtccgcatac taataaaaga
    17941 agctacaacc accataaaag gtgctacgca tgtacctaaa atacttatta gaaacatata
    18001 tgatcttttt aacttaataa attctgtacg gagtagatta tccaattgtg ccacctccta
    18061 ctaagtcttc gaaataagtt tctagattat cttctatcac tctcatctgg aaaacatcaa
    18121 tattgtttaa tactaataat ctattaattt cttgttgtct atcaatatgt gaataaattt
    18181 taaattcgcc attttcttta attttatagt cataaattcc gaagttagtt tccaacaaac
    18241 atgcaacttt ttcttcatct gatactgata tacttataaa ttgtctgttc ttttttttta
    18301 aatcttcata cataatttct tctaacaaaa ctccgttatg aataataccc accttgtcta
    18361 ctaactgctc tatttctgac aatatatgac ttgaaattaa aatggttata tttctagatt
    18421 gagccagatc cttaatcaac tttctaattt cttttatgcc aataggatct aatccattcg
    18481 tcggctcatc aagtatcaat aattcgggat tgtgcaataa agctctcgca atccctaaac
    18541 gttgcttcat acctaaagaa taatttttaa acaattttac tttttcagaa gctagtccta
    18601 ctatttctaa cacttcttca attgcatttt ctttttgtat acctaatatt ttagcattta
    18661 tagttaagtt ctctttagct gtcaaattac tataaaaacc tggcgtttca accatagcac
    18721 caatattttt taaaatttca gttttattac tttcgaactc tttttcaaat attttaatat
    18781 tacctttcgt aggtttaatt aagcctaaaa gcattcttat agtagttgtt ttgcctgcac
    18841 catttcttcc taaaaaacca taaatttgtc cactttcaac agttatactc aaattattaa
    18901 ctgctatctg acttccatat tgctttgtta agttatttat ttcaattata ttattcaaat
    18961 ttttcacctc tggcaccttt cttagtttgt tgttaccttt atcttacgcg cgattagaaa
    19021 aggctgcctt tatctattct tacaaaaaca gccgctaatc ttacaaaaat gaaagattgg
    19081 agttatttaa attgaatggt gaatattgaa ccatcgttta atgtagatgt agcacttact
    19141 ttatggccta agcgctttga gattgtgctg acaatatata aaccaatacc gcttgatttc
    19201 tcacttattc taccgttata gcccgagaaa cctttatcaa agattttcgg taaatcactc
    19261 gcattaatgc cgataccgtt atctcggatt gataatttct ttgtattttc gtcaaacgta
    19321 atccacacat ctttgccacg tgcatatttt aatgcattgt ttaatatttg ctcaatcata
    19381 attgatgccc atttggcatc tgttaatata accgcttcac ttttctcata atgcaacttt
    19441 gtttgatgat gaataaactg tatcgcataa cgtttaatca gtggtcgaat taattcatct
    19501 acactcactt ccataaagac catgtatgtc ttttggttca tgagtttcaa atagttcagt
    19561 gcaagattcg tgtaattatc aatttgtaag acttcattac gcacgttaga aatcacgtgt
    19621 tcatcaggat cttcaagcag taactttgat gctgtaatcg gtgtcttgat ttgatgcacc
    19681 cacattaaaa aatatgactc taactcactt tggtagttaa taaagtcatt acgaagttta
    19741 tggttttcga ttcttaaatc ttcgttctgt tcctgtagtg tttattcttt tttaaagttc
    19801 atgtaatgga taccccagta aatcattgaa acaaacaata caatacctag accaatcata
    19861 tatgcttgca tcggcacatt atacatgaat aatataaagt agaataaagc acaagtaagg
    19921 atgacaatat aaatttcacg ttggattgat ttcaagaaat tcatacgtca cctacacgat
    19981 atccgacatt tttcttcgtt tcgataaaat ctgtaagtcc tagtttttgt agctttttgc
    20041 gtaaacgtgt aatgttgaca gcaagcgtat tgtcatcaat gaagtgttct gattcccagc
    20101 atttttcgat taacgcatta cgactgacga atttgccctt gttctggaat aagctatgca
    20161 tgatttgcaa ttcagtgtgt gtcaggtcta tggtttcttc attaaattta agctttgctg
    20221 catcaagtag taactcgcaa tcatctactg ttaaattatt aacttgagtg gtgaaatcat
    20281 acgtgcggcg taatagtgct tgaatcttag taattgtaac agtcatatta aatggctggt
    20341 tctgttgcaa agtaaaaaat atagctaatc actaatatat catgtcagtg ttcgtttaac
    20401 ttgctagcat gatgctaatt tcgtggcatg gggaaaatcc gtagatctga agagacctac
    20461 ggttcttttt atatagagcg taaatacatt caataccttt taaagtattc tttgccgtat
    20521 tgatactttg atatcttgtc tttcttactt taatatgacg gtgatcttgc tcaatgaggt
    20581 tattcagata tttcgatgta caatgacagt caggtttaag tttaaaagct ttaattattt
    20641 tagccattgc tgccttcgtt gaaggtgcct gatctgtaac taccttttga ggcttaccaa
    20701 attgtttaat gagacgtttg ataaacgcat atgctgaatg attatctcgt tgcttacgca
    20761 accaaatatc taatgtatgt ccctctgtat caatggcacg atataaatag ctccattttc
    20821 cttttatttt gatatacgtc tcatcaatac gccatttgta ataagctttt ttatgctttt
    20881 tcttccaaat ttgatataaa attggggcat attcttgaac ccaacggtag atcgttgaat
    20941 gatgaacgtt tacaccacgt tctcttaata tttcagatat atcacgatag ctcaatgcat
    21001 atcttagata gtagccaacg gctacagtga taacatcctt gttaaattgt ttatatctga
    21061 aatagttcat acagaagact cctttttgtt aaaattatat tataaattca actttgcaac
    21121 agaaccgtat tttatgagta cactctaaat taaggagatg tataatcaat ctaaaattgt
    21181 atttttatac ttttgttata taatctttct acttagagat atattgtaaa aaaaccaaca
    21241 aaatgttata ttaacattac tattttatcg atgaaggagg attaaaatga cagcttctat
    21301 gagactcaaa taaacctttt tgaatacaaa actaaattaa ttcaaaaagg cttgtccgca
    21361 atacacactc ataggatgac ttatgtcatt ttttatcctt cgataggaat aataaacgct
    21421 ttcaaatact aaaacatcat aataaatttt taagtgtttg aaagtgtaat gtgaatgaga
    21481 cgggagtagc ctgtctcatt tttttgcgta cacgtccttt aaatatacaa ggagtgtata
    21541 aatatggaac aatatacaat taaatttaac caaatcaatc ataaattgac agatttacga
    21601 tcacttaaca tcggtcatct ttacgcttac caatttgaaa aaatagcact tattgggggt
    21661 aatggtactg gcaaaaccac attactaaat atgattgctc aaaaaacaaa accagaatct
    21721 ggaacagttg aaacggttgg cgaaattcaa tattttgaac agcttaacat ggatgtggaa
    21781 aatgatttta acacgttaga cggtagttta atgagtgaac tccatatacc tatgcataca
    21841 accgacagta tgagtggtgg tgaaaaagca aaatataaat tagctaatgt catatcaaat
    21901 tatagtccga tattactttt agatgaacct acaaatcact tggataaaat tggtaaagat
    21961 tatctgaaaa atattttaaa atattactat ggtactttaa ttatagtaag tcatgataga
    22021 gcacttatag accaaattgc tgacacaatt tgggatatac aagaagatgg cacaataaga
    22081 gtgtttaaag gtaattacac acagtatcaa aatcaatatg aacaagaaca gttagaacaa
    22141 caacgtcaat atgaacagta tataagtgaa aaacaaagat tgtcccaagc cagtaaagct
    22201 aaacgaaatc aagcgcaaca aatggcacaa gcatcatcaa aacaaaaaaa caaaagtata
    22261 gcaccagatc gtttaagtgc atcaaaacaa aaaggcacgg ttgagaaggc tgctcaaaaa
    22321 caagctaagc atattgaaaa aagaatggaa catttggaag aagttgaaaa accacaaagt
    22381 tatcatgaat tcaatttccc acaaaataaa atttatgata tccataataa ttatccaatc
    22441 attgcacaaa atctaacatt ggttaaagga agtcaaaaac tgctaacaca agtacgattc
    22501 caaataccat atggcaaaaa tatagcgctc gtaggtgcaa atggtgtagg taagacaact
    22561 ttacttgaag ctatttacca ccaaatagag ggaattgatt gttctcctaa agtgcaaatg
    22621 gcatactatc gtcaacttgc ttatgaagac atgcgtgacg tttcattatt gcaatattta
    22681 atggatgaaa cggattcatc agaatcattc agtagagcta ttttaaataa cttgggttta
    22741 aatgaagcac ttgatcgttc ttgtaatgtt ttgagtggtg gggaaagaac gaaattatcg
    22801 ttagcagtat tattttcaac gaaagcgaat atgttaattt tggatgaacc aactaatttt
    22861 ttagatatta aaacattaga agcattagaa atgtttatga ataaatatcc tggaatcatt
    22921 ttgtttacat cacatgatac aaggtttgtt aaacatgtat cagataaaaa atgggaatta
    22981 acaggacaat ctcttcatga tataacttaa aaactataca ctaatttata ttgaatatta
    23041 ggttcattta tatcaatata aaaaatacgt tcacaagaaa aatataatag aaataaggat
    23101 ccaataaaat gactcgacat aatgaaatta ttaaatgtgc agaaaaatat caattacaca
    23161 tccaacctca aacaatctca ttgaatgaat cgggacttga ttttcaagtt gcatttggaa
    23221 aagataaaca tggagtagaa tgggttttga gactaccaag aagacctgac gtttataaac
    23281 gaacaaaacc cgaaaaacaa acggtagact tcttacagaa gaatgtttca tttgaaatac
    23341 cgaagtggaa agtacatgca aaagacctta ttgcttaccc aaaacttaca ggtaaacccg
    23401 cagccacaat agatccagaa atacaaaatt atgtatggga aattgaacac aaaccattac
    23461 cagaaaactt tattaacaca ttagctgaaa cactcgtaga tttacacaac ataccagaag
    23521 aaaacattaa cgttcagcat ataaatatca aaaccataca agaaataaaa aatgactttc
    23581 aaagaagaat gaataaagtt aaagaaactt atggcgtatc agatgaatta tggaacagat
    23641 ggaaacaatg gttagaaaac gacgaactat ggcctcgaca tgcgaccatg atacatgggg
    23701 acttacatcc aggacatata atggtagata accaagcaaa cgtcacaggt ctcatagact
    23761 ggactgaagc aacccactcc gacccatcaa tggactttat aggacaccat cgtgtattcg
    23821 acgacgaagg attagagcaa cttataacag catacggtaa agctggaggt gaaatatggc
    23881 cacgaatgaa agagcatata atagaactca atgcagtatt cccaatgttt atcgctgagt
    23941 ttgctatgga atcaggagaa tcggcgtatg aaacgatggc attgaaagag ttaggtatga
    24001 aagagtagaa cttatattaa aagaggccca ttttaaagac gaaggcaatc ctgatgaaat
    24061 tttaaaactg cgtttaatta gtgatggtct ttggttttct ataatgtatt aaatatctgg
    24121 acatggaaca aatgcaacaa atggaaagaa tcgttttcga aatttctaac tccttaaatc
    24181 aggaggataa ataaacggtc attttcattg aaagcactta tataaatttc atcaatttta
    24241 atacctaccg taaatacatt tcataagtat taaacagatg attaaaattt ttagttaatt
    24301 taaatattta tgatagagat gaccttcaaa tgaacggttc tgttacaaag aaaaaatcta
    24361 tatttatttt tagtaagttt taattataga tatgtacact ttgagtacac cctaaccata
    24421 caaaaagaat tgttgaaatt ataacaatta aaacgtatga ttagggtgta tatttattat
    24481 ggagtgaaga tgaatgatta taggttatgc gagagtatca tcgatagatc aaaatttaga
    24541 aagacaattg gataatttaa agacgtttgg tgtggagaaa atctttacag agaaacagtc
    24601 gggaaagtca gtggaaaata gacctgtatt tcaagaagca ctcaattttg tcagaatggg
    24661 agatcgattc gttgtggaat ctattgatcg tttaggacgt aactatgatg aaattattga
    24721 aactgtgaat tatttaaaag aaaaagacgt tcagttaatg attaccagct tacctatgat
    24781 gaatgaagta attggcaatc cattactgga taagtttatg aaagatttaa tcattcaaat
    24841 attagcaatg gtttcagaac aagagagaaa tgaaagtaaa cgtcgacaag cgcaagggat
    24901 tcaagttgcg aaggaaaaag gcgtatataa agggcgccct ttactttatt caccaaatgc
    24961 taaagaccca cagaaacgtg ttatttatca tcgcgtggtg gaaatgttag aagaaggcaa
    25021 agcgattagt aagattgcga aagaagttaa tatcacaaga caaacagttt atagaattaa
    25081 acatgataag ggattatctt gataaattga ttgtcaatgc aaatgagcgt ctctcacagt
    25141 gtctcaaatt ccataacata ttattgaatt gagattttaa taattataca agaaaaaaga
    25201 gtacgagttc gcagctttct atatagtaat tgttttacta ataaggtgtt ttaaaatata
    25261 ttataatgta aaaagtattt gacatttgta tcaaaaatat ttacactcat aaatgtcaaa
    25321 tactttttac atttatgagg tgttataatg aatttaattc cttttattat tattttaatt
    25381 ttttcttgtt tatggacggc tataactaac aaatatttac cttcagaaac attagataaa
    25441 aaaggacaac aagatcgata cgatgaaaga caacgtaaaa tgtttattga aatactggct
    25501 aaaagtttta tttggattgt atattgtatg ttatttacac tagtgcttaa atttacaggt
    25561 ttgtcaccaa gtattgaagg atcttggttt tctcaatatc cagaaatttt ctttataatt
    25621 gtagcactat ttcttatgct gtttaattac tatactacaa ataaaaaaat atacatctaa
    25681 aggttaaatt aatgaaaaat agaattagag aatatagaaa acaaaaagga atttctcaag
    25741 aaactttaag taaagaatta aaagtgtcta ggcaaactat taatgcaata gaaaacaata
    25801 aatatgatcc tacattgaca ttagcattta agttggcaag attgtttgat acaactgtgg
    25861 atgaattatt ttcttaacca ttcatttatc acaaaaagag agtgcgaatt cgcactctct
    25921 ttttgtgtag tagtactatt aaattttgtc tcaataacga acgtttataa cgcaatcatg
    25981 atgagagtat taatacagtt aattatttga aatactttag tttacataat cgatgattac
    26041 cagaagttct cactatataa aagacactaa aattttataa cttttagtgc ctaatcaatt
    26101 attttagcta ccaaacaaac gactccaaaa ccccttttta ggttccgttt cttcactctt
    26161 ttcttctata tcactatcat tgtcatttag attagctgga acgtcttctt tttttgcttc
    26221 ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt gaatctctgt
    26281 ttctttagtt tcttcctgat ctctgttaat atttacagga ttagtagtat atgttttttc
    26341 ttgtgcatca acgttttgtc tagtgttagt agatgtatca aagggataat taaggtgttt
    26401 ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta atgccagaac
    26461 ttgctgattt tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa attcaattgt
    26521 tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtatcaa tctgattttt
    26581 aaggatttct actatttgag catcgctttt cgattcaaaa ttaatattat ccgacccttt
    26641 tttttgtttg tcttcagtag tactttcaaa accatatttc tttttatttt catttactct
    26701 ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt cctgttttat
    26761 tgtctctata ttcaatcgct taatattatt aaaaatcgtt tgcttactaa cccctaattc
    26821 ttcactcaac tttttcacac ttttcatatc atcaaccctt tataaaatgt ttataaaccc
    26881 ttgataaaat attataagct tataatgctt aataataaag tgattaataa ataaaaataa
    26941 acatccatca acctttttat caagggttta tgaaaggttt atgatattta tcaagggttt
    27001 ataaaccctt gataaagcta tattttccct tttataagtt t
//
