LOCUS       NC_006629               4440 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Staphylococcus aureus subsp. aureus COL plasmid pT181, complete
            sequence.
ACCESSION   NC_006629
VERSION     NC_006629.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603996
            Assembly: GCF_000012045.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus subsp. aureus COL
  ORGANISM  Staphylococcus aureus subsp. aureus COL
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 4440)
  AUTHORS   Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., Deboy,R.T.,
            Ravel,J., Paulsen,I.T., Kolonay,J.F., Brinkac,L., Beanan,M.,
            Dodson,R.J., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Durkin,A.S.,
            Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C.,
            Dimitrov,G., Jiang,L., Qin,H., Weidman,J., Tran,K., Kang,K.,
            Hance,I.R., Nelson,K.E. and Fraser,C.M.
  TITLE     Insights on evolution of virulence and resistance from the complete
            genome analysis of an early methicillin-resistant Staphylococcus
            aureus strain and a biofilm-producing methicillin-resistant
            Staphylococcus epidermidis strain
  JOURNAL   J Bacteriol 187 (7), 2426-2438 (2005)
   PUBMED   15774886
REFERENCE   2  (bases 1 to 4440)
  AUTHORS   Gill,S., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T.,
            Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S.,
            Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V.,
            Haft,D.H., Vamathevan,J., Khouri,H.M., Utterback,T., Lee,C.,
            Dimitrov,G., Jiang,L., Qin,H., Weidman,J., Tran,K., Kang,K.,
            Hance,I., Nelson,K.E. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 4440)
  AUTHORS   Gill,S., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T.,
            Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S.,
            Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V.,
            Haft,D.H., Vamathevan,J., Khouri,H.M., Utterback,T., Lee,C.,
            Dimitrov,G., Jiang,L., Qin,H., Weidman,J., Tran,K., Kang,K.,
            Hance,I., Nelson,K.E. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2004) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000012045.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 00:50:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,796
            CDSs (total)                      :: 2,721
            Genes (coding)                    :: 2,655
            CDSs (with protein)               :: 2,655
            Genes (RNA)                       :: 75
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 32 of 66
            Pseudo Genes (incomplete)         :: 34 of 66
            Pseudo Genes (internal stop)      :: 13 of 66
            Pseudo Genes (multiple problems)  :: 13 of 66
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000045.2.
            On Oct 5, 2005 this sequence version replaced NC_006629.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4440
                     /organism="Staphylococcus aureus subsp. aureus COL"
                     /mol_type="genomic DNA"
                     /strain="COL"
                     /sub_species="aureus"
                     /db_xref="taxon:93062"
                     /plasmid="pT181"
     gene            32..976
                     /locus_tag="SACOL_RS00005"
                     /old_locus_tag="SAA0001"
     CDS             32..976
                     /locus_tag="SACOL_RS00005"
                     /old_locus_tag="SAA0001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="WP_000277654.1"
                     /translation="MYKNNHANHSNHLENHDLDNFSKTGYSNSRLDAHTVCISDPKLSF
                     DAMTIVGNLNRDNAQALSKFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADSWD
                     RRNMRIEFNPNKLTRDEMIWLKQNIISYMEDDGFTRLDLAFDFEDDLSDYYAMSDKAVK
                     KTIFYGRNGKPETKYFGVRDSNRFIRIYNKKQERKDNADAEVMSEHLWRVEIELKRDMV
                     DYWNDCFSDLHILQPDWKTIQRTADRAIVFMLLSDEEEWGKLHRNSRTKYKNLIKEISP
                     VDLTDLMKSTLKANEKQLQKQIDFWQHEFKFWK"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            1138..2517
                     /gene="tet(K)"
                     /locus_tag="SACOL_RS00010"
                     /old_locus_tag="SAA0002"
     ARG             1139..2514
                     /name="tet(K)"
                     /gene="tet(K)"
                     /gene_name="tetracycline efflux MFS transporter Tet(K)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2703..3944
                     /gene="mobV"
                     /locus_tag="SACOL_RS00015"
                     /old_locus_tag="SAA0003"
     CDS             2703..3944
                     /gene="mobV"
                     /locus_tag="SACOL_RS00015"
                     /old_locus_tag="SAA0003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010889940.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_000122374.1"
                     /translation="MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNY
                     DLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDGLITSDNDFFDNQTPEDTKQFF
                     EYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQ
                     DRFNEHVKQRGYDLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKND
                     KLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQETGNVVISQKDFNEFQKQIKAA
                     QDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIE
                     IALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQ
                     EQQKNQKRDRGMHL"
                     /name="mobV"
     Typing          33..976
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2704..3941
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aacgaaattg agattaagga gtcgattttt tatgtataaa aacaatcatg caaatcattc
       61 aaatcatttg gaaaatcacg atttagacaa tttttctaaa accggctact ctaatagccg
      121 gttggacgca catactgtgt gcatatctga tccaaaatta agttttgatg caatgacgat
      181 cgttggaaat ctcaaccgag acaacgctca agccctttct aaatttatga gtgtagagcc
      241 ccaaataaga ctttgggata ttcttcaaac aaagtttaaa gctaaagcac ttcaagaaaa
      301 agtttatatt gaatatgaca aagtgaaagc agatagttgg gatagacgta atatgcgtat
      361 tgaatttaat ccaaacaaac ttacacgaga tgaaatgatt tggttaaaac aaaatataat
      421 aagctacatg gaagatgacg gttttacaag attagattta gcctttgatt ttgaagatga
      481 tttgagtgac tactatgcaa tgtctgataa agcagttaag aaaactattt tttatggtcg
      541 taatggtaag ccagaaacaa aatattttgg cgtgagagat agtaatagat ttattagaat
      601 ttataataaa aagcaagaac gtaaagataa tgcagatgct gaagttatgt ctgaacattt
      661 atggcgtgta gaaatcgaac ttaaaagaga tatggtggat tactggaatg attgctttag
      721 tgatttacat atcttgcaac cagattggaa aactatccaa cgcactgcgg atagagcaat
      781 agtttttatg ttattgagtg atgaagaaga atggggaaag cttcacagaa attctagaac
      841 aaaatataag aatttgataa aagaaatttc gccagtcgat ttaacggact taatgaaatc
      901 gactttaaaa gcgaacgaaa aacaattgca aaaacaaatc gatttttggc aacatgaatt
      961 taaattttgg aaatagtgta catattaata ttactgaaca aaaatgatat atttaaacta
     1021 ttctaattta ggaggatttt tttatgaagt gtctatttaa aaatttgggg aatttatatg
     1081 aggtgaaaga ataatttacc cctataaact ttagtcacct caagtaaaga ggtaaaattg
     1141 tttagtttat ataaaaaatt taaaggtttg ttttatagcg ttttattttg gctttgtatt
     1201 ctttcatttt ttagtgtatt aaatgaaatg gttttaaatg tttctttacc tgatattgca
     1261 aatcatttta atactactcc tggaattaca aactgggtaa acactgcata tatgttaact
     1321 ttttcgatag gaacagcagt atatggaaaa ttatctgatt atataaatat aaaaaaattg
     1381 ttaattattg gtattagttt gagctgtctt ggttcattga ttgcttttat tggtcacaat
     1441 cactttttta ttttgatttt tggtaggtta gtacaaggag taggatctgc tgcattccct
     1501 tcactgatta tggtggttgt agctagaaat attacaagaa aaaaacaagg caaagccttt
     1561 ggttttatag gatcaattgt agctttaggt gaagggttag gtccttcaat agggggaata
     1621 atagcacatt atattcattg gtcttaccta cttatacttc ctatgattac aatagtaact
     1681 ataccttttc ttattaaagt aatggtacct ggtaaatcaa caaaaaatac attagatatc
     1741 gtaggtattg ttttaatgtc tataagtatt atatgtttta tgttatttac gacaaattat
     1801 aattggactt ttttaatact cttcacaatc ttttttgtga tttttattaa acatatttca
     1861 agagtttcta acccttttat taatcctaaa ctagggaaaa acattccgtt tatgcttggt
     1921 ttgttttctg gtgggctaat attttctata gtagctggtt ttatatcaat ggtgccttat
     1981 atgatgaaaa ctatttatca tgtaaatgta gcgacaatag gtaatagtgt tatttttcct
     2041 ggaaccatga gtgttattgt ttttggttat tttggtggtt ttttagtgga tagaaaagga
     2101 tcattatttg tttttatttt aggatcattg tctatctcta taagtttttt aactattgca
     2161 ttttttgttg agtttagtat gtggttgact acttttatgt ttatatttgt tatgggcgga
     2221 ttatctttta ctaaaacagt tatatcaaaa atagtatcaa gtagtctttc tgaagaagaa
     2281 gttgcttctg gaatgagttt gctaaatttc acaagttttt tatcagaggg aacaggtata
     2341 gcaattgtag gaggtttatt gtcactacaa ttgattaatc gtaaactagt tctggaattt
     2401 ataaattatt cttctggagt gtatagtaat attcttgtag ccatggctat ccttattatt
     2461 ttatgttgtc ttttgacgat tattgtattt aaacgttctg aaaagcagtt tgaatagtta
     2521 tattatattt tggtttagaa ctatgagtgg ctagcatttt gccactcatt ttttgcgtta
     2581 gcaaaaacag gtttaagcct cgcagagcac acgtattaac gacttattaa aaataagtct
     2641 agtgtgttag acttaaacta ttaaatacac atgaaacctt tgtgcttagg agtgattttt
     2701 atatgtctta ttccattgtt agagtttcaa aagttaaatc tggaacaaat acaacgggca
     2761 tacaaaaaca tgttcaaaga gaaaataata attatgaaaa tgaagatata gaccatagta
     2821 aaacttactt aaattatgat ttggtaaatg ctaataaaca gaattttaat aacttgattg
     2881 atgaaaaaat cgaacagaat tatacaggca aaagaaaaat tagaacagac gcgattaaac
     2941 acattgatgg tttaattaca tcagacaatg atttctttga taatcaaacg ccagaagata
     3001 caaagcagtt ttttgaatat gctaaagagt ttttagaaca agaatacggt aaagataatt
     3061 tattatatgc aacagttcac atggacgaaa aaacaccaca tatgcattat ggcgttgttc
     3121 caataactga tgatggtcgt ttaagtgcta aagaagttgt aggtaataaa aaagctttaa
     3181 cagcgtttca agatagattt aatgagcatg ttaaacaacg aggatatgat ttagaacgtg
     3241 ggcaatcaag acaagtaaca aatgctaaac atgagcaaat aagtcagtat aaacaaaaaa
     3301 cagaatatca taagcaagaa tatgaacgtg agagccaaaa aacagaccat ataaagcaaa
     3361 agaacgataa attaatgcaa gagtaccaaa aatcgttaaa tacgcttaaa aagcctataa
     3421 atgttccgta tgagcaagaa actgaaaaag taggtggttt atttagcaaa gaaatacaag
     3481 aaactggaaa tgttgtaata agccaaaaag atttcaatga atttcagaaa cagataaaag
     3541 ctgctcaaga tatttcggaa gattacgagt atataaagtc tggtagagcc ttagatgata
     3601 aagataagga aatacgagag aaagatgatt tattaaataa agcagttgag cgtattgaaa
     3661 acgcagacga taattttaac caactttacg aaaatgcaaa gccacttaaa gagaatatag
     3721 aaatagcgtt aaagctttta aaaatcttac taaaagagtt agaacgagtt ttaggaagaa
     3781 atacctttgc ggaaagagtt aataagttaa cagaagatga accaaaacta aatggtttag
     3841 caggaaactt agataaaaaa atgaatccag aattatattc agaacaggaa cagcaacaag
     3901 aacaacaaaa gaatcaaaaa cgagatagag gtatgcactt atagaacatg catttatgcc
     3961 gagaaaactt attggttgga atgggctatg tgttagctaa cttgttagcg agttggttgg
     4021 acttgaattg ggattaatcc caagaaagta ccaactcaac aacacataaa gccctgtagg
     4081 ttccgaccaa taaggaaatt ggaataaagc aataaaagga gttgaagaaa tgaaattcag
     4141 agaagccttt gagaatttta taacaagtaa gtatgtactt ggtgttttag tagttttaac
     4201 tgtttaccag ataatacaaa tgcttaaata aaaaaagact tgatctgatt agaccaagtc
     4261 ttttgatagt gttatattaa taacaaaata aaaaggagtc gctcacgccc tgatcaaagt
     4321 ttgtgaacga catcattcaa agaaaaaaaa cactgagttg tttttataat cttgtatatt
     4381 tagatattaa acgatattta aatatacatc aagatatata tttgggtgag cgattcctta
//
