LOCUS       NC_005003               6585 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Staphylococcus epidermidis ATCC 12228 plasmid pSE-12228-06, complete
            sequence.
ACCESSION   NC_005003
VERSION     NC_005003.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603126
            Assembly: GCF_000007645.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis ATCC 12228
  ORGANISM  Staphylococcus epidermidis ATCC 12228
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 6585)
  AUTHORS   Zhang,Y.Q., Ren,S.X., Li,H.L., Wang,Y.X., Fu,G., Yang,J., Qin,Z.Q.,
            Miao,Y.G., Wang,W.Y., Chen,R.S., Shen,Y., Chen,Z., Yuan,Z.H.,
            Zhao,G.P., Qu,D., Danchin,A. and Wen,Y.M.
  TITLE     Genome-based analysis of virulence genes in a non-biofilm-forming
            Staphylococcus epidermidis strain (ATCC 12228)
  JOURNAL   Mol Microbiol 49 (6), 1577-1593 (2003)
   PUBMED   12950922
REFERENCE   2  (bases 1 to 6585)
  AUTHORS   Zhang,Y., Ren,S., Li,H., Fu,G., Lu,L., Lu,G., Jia,J., Tu,Y., Qin,Z.,
            Chen,Z. and Wen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2002) Chinese National Human Genome Center at
            Shanghai, 250 Bi Bo Road, Shanghai 201203, China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000007645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 00:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,440
            CDSs (total)                      :: 2,359
            Genes (coding)                    :: 2,283
            CDSs (with protein)               :: 2,283
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 49 of 76
            Pseudo Genes (incomplete)         :: 40 of 76
            Pseudo Genes (internal stop)      :: 25 of 76
            Pseudo Genes (multiple problems)  :: 28 of 76
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AE015935.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6585
                     /organism="Staphylococcus epidermidis ATCC 12228"
                     /mol_type="genomic DNA"
                     /strain="ATCC 12228"
                     /db_xref="ATCC:12228"
                     /db_xref="taxon:176280"
                     /plasmid="pSE-12228-06"
     gene            51..245
                     /locus_tag="SE_RS12105"
                     /old_locus_tag="p601"
                     /old_locus_tag="SE_p601"
     CDS             51..245
                     /locus_tag="SE_RS12105"
                     /old_locus_tag="p601"
                     /old_locus_tag="SE_p601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002447414.1"
                     /translation="MKKISKLLIAFSLVTTLSYASASTGFMNDNSHEAFAKSKKKKHKG
                     NGNKHNCFPVGNSEFCTTP"
                     /name="hypothetical protein"
     gene            341..1141
                     /locus_tag="SE_RS12110"
                     /old_locus_tag="p602"
                     /old_locus_tag="SE_p602"
     CDS             341..1141
                     /locus_tag="SE_RS12110"
                     /old_locus_tag="p602"
                     /old_locus_tag="SE_p602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498218.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_002498218.1"
                     /translation="MKSSLFILKEHFNNLYLMKRLAQFEMKISNKNNYLGTAWELINPS
                     IQIFMYWFIFGLGFRNNRTVENIPFIFWLIVGISMWFFVNQGILNGTKAVTSKYKQVAK
                     MNFPLSILSSYIVLSKFYTHVLLLILIMLICALNGYYPTIYTLQLLIFIPYTLLLTMTI
                     TLLTSTLAVIIRDIQMLMQALMRIIFFISSILYLPTNALVLKVIQFNPIYFIAESYRAA
                     ILYQNWFFITHWKLSLYNLAFLLITFVLGSILHVKYREQFADFL"
                     /name="ABC transporter permease"
     gene            1477..1863
                     /gene="mobC"
                     /locus_tag="SE_RS12115"
                     /old_locus_tag="p603"
                     /old_locus_tag="SE_p603"
     CDS             1477..1863
                     /gene="mobC"
                     /locus_tag="SE_RS12115"
                     /old_locus_tag="p603"
                     /old_locus_tag="SE_p603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_011117491.1"
                     /translation="MSEQNTFVASDETVGRNRKPNRKAPKQISFRVSESEYLKLQQSAE
                     TLNMSVPAFVKKKAQGARLVAPKLDQATRQSVAKDLSMLGANANQIAKYCNQHQHEAPN
                     YEALERNISELRERLDEIWNMIQK"
                     /name="mobC"
     gene            2029..3039
                     /locus_tag="SE_RS12120"
                     /old_locus_tag="p605"
                     /old_locus_tag="SE_p605"
     CDS             2029..3039
                     /locus_tag="SE_RS12120"
                     /old_locus_tag="p605"
                     /old_locus_tag="SE_p605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_002498904.1"
                     /translation="MATTKLSATKSTSRAINYAEKRAVEKSGLNCDVDYAKSSFKAARE
                     LYGKTDGNQGHVIIQSFQPGEVTPEQCNQLGLALAEKLVPNHQVAVYTHADTNHVHNHI
                     VLNSIDLNTGKKFNNNKQALRDVRAFNDEVCRAQGLSVPEKDTARLRYTQTEKAIADPN
                     TTSTAQYSWKDDIREAIDQSTATNMEEFQKHLNQHGITIERVTPKSITYRHLAENKKVR
                     GRKLGEDYNKGGIQHGFERQIQRRQQQKHKSDTNFQPKRSTSNRHESTERDTGVTQSDW
                     DQFAQDTNELERRRQAAESARLVDEKARRDREKRVREKPTSRPIINIDRDHGLEL"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2942..3547
                     /locus_tag="SE_RS12125"
                     /old_locus_tag="p606"
                     /old_locus_tag="SE_p606"
     CDS             2942..3547
                     /locus_tag="SE_RS12125"
                     /old_locus_tag="p606"
                     /old_locus_tag="SE_p606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="WP_077431415.1"
                     /translation="MKRLEEIEKREYERNQRHDQLLTSIETTASNFNQATDFTQKRFIS
                     AARHYIERINNDNLKQDFHTAIQKELEDVKTDTQNVVKEVQNNQSELRQANNNYKKMID
                     ERMKSNAIVIKQYDQVIHRLTKGITAMFFIVALVMVAFLVISPLGDWLGVQHFYEWLNH
                     VLKTGHSAWRYFMLVFYLVPYILFGVLIYAILKAYERL"
                     /name="mobilization protein"
     gene            4392..5249
                     /locus_tag="SE_RS12130"
                     /old_locus_tag="p608"
                     /old_locus_tag="SE_p608"
     CDS             4392..5249
                     /locus_tag="SE_RS12130"
                     /old_locus_tag="p608"
                     /old_locus_tag="SE_p608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458658.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_002498908.1"
                     /translation="MSGETVVYKNDMNLVPLRKFNNTEVNLFFTLCNKLKDKGNLTVNV
                     PFEELKELSNYYSHDKKLFIQDLEKFYDKVFSLTYREETENVIRKFILFTKVEIYKDKE
                     YVAIGVNPDLEHIINSLTSNFTKFELKEMTHLKSTYSKHMFRILKQYKHTGYVKIKIDD
                     FRERLDIPNSYRMTNINQKVLAPIIKELGFIFNNLNINKIKAKKGRKIEWLEFTFDAEK
                     RIHNKRQPQMANIDKSRQYISREKTPRWLEERTYEKQIKNEYDPQLEKERKAFLKQLQL
                     DWED"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(5297..5902)
                     /locus_tag="SE_RS12135"
                     /old_locus_tag="p609"
                     /old_locus_tag="SE_p609"
     CDS             complement(5297..5902)
                     /locus_tag="SE_RS12135"
                     /old_locus_tag="p609"
                     /old_locus_tag="SE_p609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002498907.1"
                     /translation="MNKSKVAEIRKQKSLTQENLAEKAYVTVRTIQRMEAGEEVSSETL
                     KSVSNALDVTVNELFESISSSDKEEEIMEISKEQQKQFNYRKNELFTIKLITFSFIFVF
                     LGLFGIFVGELNGLEQNIYRIIWIFALFLSLAIMYYFLNVFISKKLDKKYPMTIGMKNR
                     NRKNEPVKNGWDFMARYWWIVFPIGGFLSWLIPELTGK"
                     /name="helix-turn-helix domain-containing protein"
     Typing          complement(1268..1506)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.72e-122"
     Typing          4426..5249
                     /name="rep_cluster_1256"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2021..3036
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.705"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cttaaaattg tgatatcttt actttaaatt aatattttgg aggggtagaa atgaaaaaaa
       61 tctcgaaact tcttattgca ttttcattag taacaacact atcatatgca agtgcttcaa
      121 ctggttttat gaatgataac tctcatgaag catttgctaa atctaaaaag aaaaaacata
      181 aaggaaatgg taacaaacat aattgcttcc cagtcggaaa cagtgaattt tgtacaactc
      241 cataattaaa atagaaaagg taaagcaata aacaattgct ttaccttttt tttaggtttc
      301 atttataata ttgataatct tagaaaggta acttaatgtt atgaaatcat ctttgtttat
      361 attaaaagaa cattttaata atttatattt aatgaaaaga ttagcacaat ttgaaatgaa
      421 aatttctaac aaaaataatt atttgggaac agcatgggaa ttaattaatc cttcaataca
      481 gatttttatg tattggttta tttttggttt aggtttcaga aataatagaa ctgttgagaa
      541 tatacctttt attttttggt taattgtagg aataagtatg tggttttttg tgaatcaagg
      601 tattttaaat ggtacaaaag cagttactag caaatataag caagtagcta aaatgaattt
      661 tccattatct atattatcta gttatatcgt cttaagtaaa ttttataccc atgtgttatt
      721 gcttatttta attatgctta tatgtgcttt aaatggatat taccctacta tatatacatt
      781 acaattatta atttttatcc cttacactct gttactgaca atgacaataa cactattaac
      841 ttcaacatta gctgtaatta ttagagacat ccaaatgctt atgcaagctc ttatgagaat
      901 aatatttttt atatcttcaa ttttatattt accgacaaat gctttagttt taaaggttat
      961 acaatttaat cctatctatt ttatagctga aagttataga gcagcaattc tatatcaaaa
     1021 ttggtttttt ataacacatt ggaaactatc tttatataat cttgctttcc ttttaattac
     1081 ttttgtgttg ggctctattt tacatgttaa atatcgtgaa caatttgcag attttttata
     1141 aacagaatat aaagaacatt atttttgatc ttattctcat ttctttttta attttatttt
     1201 tcatttgggt ttaataatta tagcaaaaat atttttggtt gctgcggttt tgatggtttt
     1261 gaatttagtg gctagcaatt agccactatt ttttcgttag aaaaaatcca taaggggctt
     1321 ggggattacc cccaacaagc aggcgcgtct gccacgttag tggctagcaa agccaatgct
     1381 tgccaaacca cttaacgact tgatgaatct tactttatca tataaagtaa gatgtaagaa
     1441 cggcgttatc tttcgaagaa agcgtggtgg gattgaatga gcgaacaaaa cacatttgtg
     1501 gctagcgacg aaactgttgg gcgaaaccgt aaacccaacc gtaaggcgcc gaaacaaatt
     1561 agttttcgtg tgagcgaatc cgaatattta aagttacaac aatcagctga aactttaaat
     1621 atgagtgttc ctgcgttcgt taagaaaaag gcacaaggcg cccgattggt cgcacccaaa
     1681 ttggatcaag caacgcgaca atcggtagct aaagatttaa gtatgttggg tgcaaatgcc
     1741 aatcagattg cgaaatattg caaccaacat caacacgaag caccgaacta cgaagcatta
     1801 gaacgtaaca ttagtgaatt acgtgaaagg ttagatgaga tatggaacat gatccaaaaa
     1861 taaaaatgat tgtaagtgcc attttatttg tgatgtgttt aatgatattg ttttatttta
     1921 ttttctttga tccacaattt ccggtgattt tgtgtttttc acttttaact tttatcacag
     1981 gtattgattt atatatatca tataaaaaga aaaaagcgcg tgataccaat ggcaacaact
     2041 aaattaagtg cgactaaatc aacatcacgg gccatcaatt acgctgaaaa acgtgccgtt
     2101 gagaaaagtg gcttaaattg tgacgtggac tatgccaaat ctagttttaa agccgctcgt
     2161 gaattgtatg gcaaaacaga cggtaatcaa gggcatgtca ttatccaatc gtttcaacct
     2221 ggcgaagtga cgcccgaaca atgtaaccaa ttaggattag cgcttgctga aaaactcgtc
     2281 cccaatcatc aagtcgccgt ctatacgcat gcagatacaa accatgtaca caatcatatt
     2341 gtacttaatt caattgacct caatacaggt aagaaattta acaataataa acaagcccta
     2401 cgcgatgtga gagcgttcaa cgacgaggtt tgtcgagcac aggggttgag cgtgcctgag
     2461 aaagacacag cacgcttacg ttacacccaa acagaaaaag cgattgccga ccctaacacg
     2521 acgtcgacag cacaatactc atggaaagat gacatacgtg aggcaattga ccaatcaaca
     2581 gcgacaaata tggaagaatt tcaaaaacat ctgaatcaac atggtattac gattgaacgt
     2641 gttaccccca aaagcattac ctatcggcat ttagctgaaa ataaaaaagt acgcgggcgt
     2701 aaattgggcg aagattacaa taaaggaggc atccaacatg gctttgaaag acaaatacaa
     2761 cgacgacaac aacaaaaaca taaatcagac acgaacttcc agccaaaacg atcaacttca
     2821 aaccgtcatg aatcaactga acgagataca ggcgtcactc aatcagattg ggaccaattc
     2881 gcccaagaca caaatgagct tgagcgtcgc cgacaagctg cagaatcagc aagacttgtt
     2941 gatgaaaagg ctcgaagaga tcgagaaaag agagtacgag agaaaccaac gtcacgacca
     3001 attattaaca tcgatcgaga ccacggcctc gaactttaat caagccacag acttcacaca
     3061 aaagcgtttt ataagcgcgg caagacatta tattgaacgg attaataacg ataatttaaa
     3121 acaagatttt cacacagcta tacaaaaaga attagaagat gtcaaaacag acacacaaaa
     3181 cgtagttaag gaagttcaaa acaaccaatc cgaactgcga caagccaata ataattataa
     3241 aaaaatgatt gatgaacgta tgaagagcaa cgcaatagtg attaaacaat atgatcaagt
     3301 catacatcgt ttaactaaag gcatcacagc catgtttttt atcgttgcct tagtgatggt
     3361 cgccttttta gttataagtc ccttaggtga ctggttaggc gtccaacatt tttacgaatg
     3421 gctgaaccac gtgcttaaaa cggggcattc agcatggcgt tatttcatgc ttgttttcta
     3481 tcttgtacct tatattttat ttggagtgct tatatatgcc attttaaaag catatgagcg
     3541 tctttaatac aaaataaata gaaaattacc ttttgtttaa tgaagaagct atatcaagct
     3601 taaaatagcg tagaaaccaa aaaggagtgc tcgccttgaa ttctattgtt cactttattt
     3661 gtttttttat tgtattttgt ctttttggat atgtggtcaa cttaatattt tttgaaggaa
     3721 caaatatttt tctgatttta gaatcagcat ttattttatc attactaatc acaccgatat
     3781 taaaggttgt aaaagatatg gaaaatgaag aatagcacat gcgcttatgc cgagaaaatt
     3841 tattgagcat tgagaagaac ccttaattaa actgtttcga cgaatgtcgg gatagtgtga
     3901 gctatgaaac cgacgagtcg acagttttag ggtttattaa gggttcagag gctcaatgtc
     3961 aataaagcaa ttggaataat gcattaaagt tatatcactt attacttttt taaataataa
     4021 aaacccacca caaatgtggt gggtttcctt tttgtctttt gaatttgtga ggggcaaatt
     4081 gccccgaact ttttaatatc tttttataaa tctttttaaa acctttttag gagtcatttg
     4141 atccttagag tgacaataga tttgaaatgt taaaggcaac caatcattaa actaaaggca
     4201 accaatcatt aaactaaagg caaccaatca ttaaactaaa ggcaaccaat cattaaacta
     4261 aagaaacttt ttttatatta ggtttcttta tgttattatt gtttataaca tagtgattat
     4321 aagtatttac aattaaagtt aataggaatc tttattctat ataggtttct tttagattgg
     4381 agtggagtta gttgagtgga gaaacagtag tatataaaaa tgatatgaat ttagttccac
     4441 tgagaaaatt taataatact gaagttaatc tattttttac tttgtgtaat aaattaaaag
     4501 ataaaggcaa tttgactgtt aatgtgccat ttgaagaatt aaaagaatta agtaattact
     4561 atagtcatga taaaaagctt tttattcaag atttagaaaa attctatgac aaagttttct
     4621 ctttaacata tagagaagaa actgagaatg ttattagaaa atttattctt tttactaaag
     4681 tagaaattta taaagataaa gagtatgtgg ctattggtgt taatccagat ttagaacata
     4741 ttattaattc attaactagt aacttcacta aatttgaact taaagaaatg acacacctta
     4801 aatctacata ttctaagcat atgttcagaa tacttaagca gtataaacat actggctatg
     4861 taaaaattaa aattgatgat tttagagaac ggctggatat tcctaatagt taccgtatga
     4921 caaatattaa tcaaaaagta ttagccccta tcattaaaga attaggcttt atttttaata
     4981 accttaatat caataaaata aaggcaaaaa aaggacgtaa aattgaatgg ttagagttta
     5041 cttttgacgc tgagaaacgc attcacaata aacgacagcc acaaatggcg aatatagata
     5101 agtcacgaca atatataagt cgggaaaaaa cgccgagatg gttagaagaa cgtacttatg
     5161 aaaaacaaat aaaaaatgaa tatgatccac aattagaaaa agagcgaaaa gcatttttaa
     5221 aacaacttca attagactgg gaagattaaa acaaaagatc tttagccccc ttgctaaaga
     5281 tcttttgttt tgtattttat tttcctgtta attcaggaat tagccaactt agaaaccctc
     5341 caataggaaa aacaatccac caatatctag ccataaaatc ccagccattt tttacaggtt
     5401 cattttttct atttctattt ttcattccaa tagtcatagg atatttttta tctaattttt
     5461 ttgaaataaa aacatttaaa aaataataca ttattgctaa gctcaaaaat aaagcgaaaa
     5521 tccaaatgat gcggtaaata ttttgttcta aaccgtttaa ctcacctaca aagattccaa
     5581 atagtcctaa aaacacaaaa ataaaactaa atgttattaa tttaatagta aaaagttcat
     5641 ttttacgata attaaactgc ttttgttgtt ctttagatat ttccattatt tcctcctcct
     5701 tatcagaaga cgagatagat tcgaatagtt cattgactgt cacatctaat gcgtttgaga
     5761 cacttttaag tgtttcacta ctaacttctt ctccagcctc cattctttga attgttctta
     5821 ctgttacata agccttttct gctaaatttt cttgagttaa cgatttttgt tttctaattt
     5881 ctgcaacttt tgatttgttc atactcataa actactcctc aactaaaaaa atgaacacga
     5941 aaaattgccg acagatgggc gacaatgaaa cgacagttac ttcaaaatta tattcttaaa
     6001 agaaagtata tatctaattt tacaaaaagc ataagaaagg atatactgaa agtaacaaat
     6061 agcagatata tcattgtatg tgaaaacccc cagcgtgccg gctgggggtt tctttttact
     6121 tatgctcttg ttgtaataga taaagaacat aaccaacaat aattggaaaa atgagcttat
     6181 ctagtacaaa tagcaagatt atcattgtat gtgacacctc ctttgtgcac ggaagtgctt
     6241 ttccagtata acaaaaaact acaatttaaa acggtgtgtt atcacgtgaa attgtgaata
     6301 aagatacaaa agttcactta atgaaaaaga atgaaaacac gtgagaacaa cgatgtataa
     6361 aagatgaata aacgataatc acaagacaaa ggcttaaacg ttgatttaac agcgtttaag
     6421 cctttattgt tagttgacat aattactgat tataggtagt tagtttgtat agaatacgta
     6481 taatttgtaa aattgaatag aatattaaaa aattctatat tttactcttc aaaaatatat
     6541 gctaaaacca attaataaat ttatattttt ttcgtcttga ttttt
//
