LOCUS       CP152458               29412 bp    DNA     circular BCT 01-MAY-2024
DEFINITION  Staphylococcus aureus strain BSN132 plasmid pBSN132, complete
            sequence.
ACCESSION   CP152458
VERSION     CP152458.1
DBLINK      BioProject: PRJNA1048360
            BioSample: SAMN38637710
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 29412)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN132 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29412)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN132
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: CP030326, CP092053, CP042087, MN216340
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/25/2024 11:36:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,901
            CDSs (total)                      :: 2,819
            Genes (coding)                    :: 2,739
            CDSs (with protein)               :: 2,739
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 44 of 80
            Pseudo Genes (incomplete)         :: 38 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 28 of 80
            ##Genome-Annotation-Data-END##
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..29412
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN132"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pBSN132"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-08-28"
                     /collected_by="Andrew D. Berti"
     gene            7..399
                     /locus_tag="UXQ16_14300"
     CDS             7..399
                     /locus_tag="UXQ16_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0008080 - N-acetyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="XAH95950.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            400..1839
                     /gene="aph(2'')-Ia"
                     /locus_tag="UXQ16_14305"
     CDS             400..1839
                     /gene="aph(2'')-Ia"
                     /locus_tag="UXQ16_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="XAH95951.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(1969..2286)
                     /locus_tag="UXQ16_14310"
                     /pseudo=""
     CDS             complement(1969..2286)
                     /locus_tag="UXQ16_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /name="IS256 family transposase"
     gene            2363..3037
                     /locus_tag="UXQ16_14315"
     CDS             2363..3037
                     /locus_tag="UXQ16_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="XAH95952.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAIAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEIRDML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(3147..4607)
                     /gene="zwf"
                     /locus_tag="UXQ16_14320"
     CDS             complement(3147..4607)
                     /gene="zwf"
                     /locus_tag="UXQ16_14320"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004345 - glucose-6-phosphate dehydrogenase activity
                     [Evidence IEA]; GO_process: GO:0006098 - pentose-phosphate
                     shunt [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="XAH95953.1"
                     /translation="MDKNLSSLITIFGGTGDLSYRKLLPSIFNLYKKGHFKKLVIISTG
                     LEDISDEEYRSKVKQILLSRENFEMVNLFLDNIFYFQQNVEDKTSWNKLKELSNDIDKK
                     YCLDGNRLFYLAMNPQFFKIITQSISQSGLSDTNGFSRLIIEKPFGKDLKSAEDLNKHI
                     RQYFKEEEIFRIDHYLGKEMVQNIESLRFGNTIFEPLWNNKYISNVQITLSETLGIEDR
                     GQYYDSTGALKDMVQNHALQILTLIAMEKPESRNSKDIRLKKIELLNNIKFLKGADVHK
                     YFVRGQYINGIINETPIMSYHEEKGVDSDSTTETFVAGKVLINNRRWEGTPFYIRTGKR
                     LGKKATEIVIEFKKNNNTLRYENNNEDTDCNLLVINIEPNAKISLYIYENKSNRNNRSH
                     NMKIYNSIDKNQVVDAYESLICDALIGNQTNFVHWEELKQSWEFIDYISTEWKKSNVTI
                     PQYKPGSFGPKESDQLLKQDNFEWWNNL"
                     /name="zwf"
     gene            complement(4671..6077)
                     /gene="gndA"
                     /locus_tag="UXQ16_14325"
     CDS             complement(4671..6077)
                     /gene="gndA"
                     /locus_tag="UXQ16_14325"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]; GO_function:
                     GO:0050661 - NADP binding [Evidence IEA]; GO_process:
                     GO:0006098 - pentose-phosphate shunt [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="XAH95954.1"
                     /translation="MSSNIGILGLGVMGKNLAWNIEDKKYSVSIHSRDNNEINDTIQKS
                     HYQKIYPAYNLKEFVDSLEKPRKILLMIKAGSPTDNMINALLPLLDDEDILIDGGNTNY
                     QDTIRRNKTLAESGVNFIGMGVSGGEVGALTGPSLMPGGQEAAYNKVSDILDAIAAKAQ
                     DGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYTMMKDLLGMSHTEISQTFKDWN
                     AGELESYLIEITGDIFTKLDENNEPLVEKILDTAGQKGTGKWTSINALELGIPLTIITE
                     SVFARFISSIKEERVNASKSLNGPQASFDGNKEEFLEKIRKALYMSKICSYAQGFAQMR
                     KSSEDHEWNLKLGELAMIWREGCIIRAQFLQKIKDAYDNNPELENLLLDPYFKNIVTDY
                     QDALRDVVATGVKNGVPTPGFSASVNYYDSYRSEDLPANLIQAQRDYFGAHTYERKDHE
                     GVFHTQWDEE"
                     /name="gndA"
     gene            complement(6109..7440)
                     /locus_tag="UXQ16_14330"
     CDS             complement(6109..7440)
                     /locus_tag="UXQ16_14330"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004347 - glucose-6-phosphate isomerase activity
                     [Evidence IEA]; GO_process: GO:0006096 - glycolytic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="XAH95955.1"
                     /translation="MTHIQLDYGKTLEFFGEHELEQQKDIVKTLHKTIHGGTGAGNDFL
                     GWVDLPVDYDKEEFSRIVEASKRIKANSDVLVVIGIGGSYLGARAAIEMLTSSFRTNND
                     YPEIVFVGNHLSSSYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVESKYGK
                     EEAKKRIFATTDKQKGALKQLATNEGYETFVVPDDVGGRYSVLTAVGLLPIAAAGINIE
                     AMMIGAAKARKELSSDKLEENIAYQYATIRNLLYSKGYTTEMLINYEPSMQYFNEWWKQ
                     LFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKHDLTIEEDSD
                     DLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNIVVNIPQLDEETFGYVVYFFELAC
                     AMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDMKKDLEARL"
                     /name="glucose-6-phosphate isomerase"
     gene            7641..8273
                     /gene="hxlA"
                     /locus_tag="UXQ16_14335"
     CDS             7641..8273
                     /gene="hxlA"
                     /locus_tag="UXQ16_14335"
                     /EC_number="4.1.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0043801 - hexulose-6-phosphate synthase activity
                     [Evidence IEA]; GO_process: GO:0019647 - formaldehyde
                     assimilation via ribulose monophosphate cycle [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="XAH95956.1"
                     /translation="MELQLAIDLLNKEEAAELAKKVEEYVDIVEIGTPIVINEGLPAVQ
                     HLNENISNAKVLADLKIMDAADYEVSQAVKFGADVVTILGVAEDASIKAAVEEAHKNNK
                     QLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLDSLRKVKSVIKNSKVA
                     VAGGIKPDTIKEIVAEEPDLVIVGGGIANADDPVEAAKQCRDAIEGK"
                     /name="hxlA"
     gene            8276..8824
                     /gene="hxlB"
                     /locus_tag="UXQ16_14340"
     CDS             8276..8824
                     /gene="hxlB"
                     /locus_tag="UXQ16_14340"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0043800 - hexulose-6-phosphate isomerase activity
                     [Evidence IEA]; GO_process: GO:1901135 - carbohydrate
                     derivative metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="XAH95957.1"
                     /translation="MTTFNHYQLILDELKGTLSHVKDEEFDGFASEVTEASRIFVAGKG
                     RSGFVANSFAMRLNQLGKQAFVIGESTTPSIQKDDLFIVISGSGSTEHLRLLAEKAKSV
                     DAKVVLLTTKLDSAIGEIADTVVELPAGTKHDATGSDQPLGSLFEQSSQIFLDSVVIGL
                     MTQLDVDETTMQNNHANLE"
                     /name="hxlB"
     gene            8914..9246
                     /locus_tag="UXQ16_14345"
     CDS             8914..9246
                     /locus_tag="UXQ16_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="XAH95958.1"
                     /translation="MYYKGKEFFTSKDLALCVIGGKWKIPIIFHLLQDKVLRLSELQKK
                     LPHVNQRMLIRQLRELEEDQIIERHIYSVVPPKVEYKLTSIGYKLDKVVYAICEWGDLF
                     KDEIIH"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(9411..10085)
                     /locus_tag="UXQ16_14350"
     CDS             complement(9411..10085)
                     /locus_tag="UXQ16_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="XAH95959.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKTFKLNPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSVNTAKNTLKGIECIYGLYKKSRRSLQIYGFSPCHEISYML
                     AG"
                     /name="IS6 family transposase"
     gene            10250..10345
                     /locus_tag="UXQ16_14355"
     CDS             10250..10345
                     /locus_tag="UXQ16_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAH95960.1"
                     /translation="MLEILVHITTTVISGCIIALFTHWLRNRNNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(10495..10725)
                     /locus_tag="UXQ16_14360"
     CDS             complement(10495..10725)
                     /locus_tag="UXQ16_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002471858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH95961.1"
                     /translation="MDSIENACLISQITFKVNSPYKNMSEDYMDIKESDRIIMKAILNK
                     CGIDLQKSNHKLNNVMPSYNVFIRKDELDYR"
                     /name="hypothetical protein"
     gene            11092..11700
                     /locus_tag="UXQ16_14365"
     CDS             11092..11700
                     /locus_tag="UXQ16_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAH95962.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRDYDEIIETVSYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGSS"
                     /name="recombinase family protein"
     gene            complement(11910..12476)
                     /gene="qacR"
                     /locus_tag="UXQ16_14370"
     ARG             complement(11914..12476)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            12653..14197
                     /gene="qac"
                     /locus_tag="UXQ16_14375"
     CDS             12653..14197
                     /gene="qac"
                     /locus_tag="UXQ16_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="XAH95964.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIVSSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFVIIAIVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMTSVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGTASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            14402..14962
                     /locus_tag="UXQ16_14380"
     CDS             14402..14962
                     /locus_tag="UXQ16_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH95965.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(15278..16021)
                     /locus_tag="UXQ16_14385"
     CDS             complement(15278..16021)
                     /locus_tag="UXQ16_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="XAH95934.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            16447..17430
                     /locus_tag="UXQ16_14390"
     CDS             16447..17430
                     /locus_tag="UXQ16_14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="XAH95935.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17450..17739
                     /locus_tag="UXQ16_14395"
                     /pseudo=""
     CDS             17450..17739
                     /locus_tag="UXQ16_14395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            18286..18435
                     /locus_tag="UXQ16_14400"
     CDS             18286..18435
                     /locus_tag="UXQ16_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH95936.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(18603..19295)
                     /locus_tag="UXQ16_14405"
     CDS             complement(18603..19295)
                     /locus_tag="UXQ16_14405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="XAH95937.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            19405..19599
                     /locus_tag="UXQ16_14410"
     CDS             19405..19599
                     /locus_tag="UXQ16_14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH95938.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            20715..21332
                     /gene="cadD"
                     /locus_tag="UXQ16_14415"
     ARG             20716..21329
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            21351..21698
                     /locus_tag="UXQ16_14420"
     CDS             21351..21698
                     /locus_tag="UXQ16_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="XAH95940.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            21855..21947
                     /locus_tag="UXQ16_14425"
     CDS             21855..21947
                     /locus_tag="UXQ16_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAH95941.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(22119..23090)
                     /locus_tag="UXQ16_14430"
     CDS             complement(22119..23090)
                     /locus_tag="UXQ16_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="XAH95942.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            23214..23633
                     /locus_tag="UXQ16_14435"
     CDS             23214..23633
                     /locus_tag="UXQ16_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="XAH95943.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(24147..24992)
                     /gene="blaZ"
                     /locus_tag="UXQ16_14440"
     ARG             complement(24151..24992)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            25099..26856
                     /gene="blaR1"
                     /locus_tag="UXQ16_14445"
     ARG             25100..26853
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            26846..27226
                     /gene="blaI"
                     /locus_tag="UXQ16_14450"
     ARG             26847..27223
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            27490..28068
                     /locus_tag="UXQ16_14455"
     CDS             27490..28068
                     /locus_tag="UXQ16_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAH95947.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(28291..28476)
                     /locus_tag="UXQ16_14460"
     CDS             complement(28291..28476)
                     /locus_tag="UXQ16_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH95948.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            28738..29412
                     /locus_tag="UXQ16_14465"
     CDS             28738..29412
                     /locus_tag="UXQ16_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="XAH95949.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAIAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEIRDML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     ARG             12654..14194
                     /name="qacB"
                     /gene="qacB"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacB"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.42"
                     /coverage="100.0"
     ARG             401..1836
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             401..1839
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(24148..24992)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     Typing          17796..17943
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15279..16021)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16448..17430
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17562..17731
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gagtttatgg aagaagtttt aattgatgat aatatggttt ttgatattga taatttaaaa
       61 ggatttctta atgataccag ttcatttggg tttatagcta aagaaaataa taaaattata
      121 ggatttgcat attgctatac acttttaaga cctgatggaa aaacaatgtt ttatttacac
      181 tcaataggaa tgttacctaa ctatcaagac aaaggttatg gttcaaaatt attatctttt
      241 attaaggaat attctaaaga gattggttgt tctgaaatgt ttttaataac tgataaaggt
      301 aatcctagag cttgccatgt atatgaaaaa ttaggtggta aaaatgatta taaagatgaa
      361 atagtatatg tatatgatta tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa
      421 atatgtataa gaactttaat agatgatgat tttcctttga tgttaaaatg gttaactgat
      481 gaaagagtat tagaatttta tggtggtaga gataaaaaat atacattaga atcattaaaa
      541 aaacattata cagagccttg ggaagatgaa gtttttagag taattattga atataacaat
      601 gttcctattg gatatggaca aatatataaa atgtatgatg agttatatac tgattatcat
      661 tatccaaaaa ctgatgagat agtctatggt atggatcaat ttataggaga gccaaattat
      721 tggagtaaag gaattggtac aagatatatt aaattgattt ttgaattttt gaaaaaagaa
      781 agaaatgcta atgcagttat tttagaccct cataaaaata atccaagagc aataagggca
      841 taccaaaaat ctggttttag aattattgaa gatttgccag aacatgaatt acacgagggc
      901 aaaaaagaag attgttattt aatggaatat agatatgatg ataatgccac aaatgttaag
      961 gcaatgaaat atttaattga gcattacttt gataatttca aagtagatag tattgaaata
     1021 atcggtagtg gttatgatag tgtggcatat ttagttaata atgaatacat ttttaaaaca
     1081 aaatttagta ctaataagaa aaaaggttat gcaaaagaaa aagcaatata taatttttta
     1141 aatacaaatt tagaaactaa tgtaaaaatt cctaatattg aatattcgta tattagtgat
     1201 gaattatcta tactaggtta taaagaaatt aaaggaactt ttttaacacc agaaatttat
     1261 tctactatgt cagaagaaga acaaaatttg ttaaaacgag atattgccag ttttttaaga
     1321 caaatgcacg gtttagatta tacagatatt agtgaatgta ctattgataa taaacaaaat
     1381 gtattagaag agtatatatt gttgcgtgaa actatttata atgatttaac tgatatagaa
     1441 aaagattata tagaaagttt tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa
     1501 aagtgtttat gccataatga ttttagttgt aatcatctat tgttagatgg caataataga
     1561 ttaactggaa taattgattt tggagattct ggaattatag atgaatattg tgattttata
     1621 tacttacttg aagatagtga agaagaaata ggaacaaatt ttggagaaga tatattaaga
     1681 atgtatggaa atatagatat tgagaaagca aaagaatatc aagatatagt tgaagaatat
     1741 tatcctattg aaactattgt ttatggaatt aaaaatatta aacaggaatt tatcgaaaat
     1801 ggtagaaaag aaatttataa aaggacttat aaagattgat tatataatat atgaaaagct
     1861 attataaaag acattagtat taaatagttt aaaaaaatga aaaataataa aggaagtgag
     1921 tcaagtccag actcctgtgt aaaatgctat acaatgtttt taccatttct acttatcaaa
     1981 attgatgtat tttcttgaag aataaatcca ttcatcatgt aggtccataa gaacggctcc
     2041 aattaagcga ttggctgatg tttgattggg gaagatgcga ataatctttt ctcttctgcg
     2101 tacttcttga ttcagtcgtt caattagatt ggtactcttt agtcgattgt gggaatttcc
     2161 ttgtacggta tattgaaagg cgtcttcgaa tccatcatcc aatgatgcgc aagcttttga
     2221 atattttggt tgatcgatat aatcatgaat caatcgattt ttagcctcac gcgctaagtt
     2281 aatatcttta ccaccattcc taaaaaggtt ctgttgcaaa gttgaattta tagtataatt
     2341 ttaacaaaaa ggagtcttct gtatgaacta tttcagatat aaacaattta acaaagatgt
     2401 tatcactgta gccgttggct actatctaag atatgcattg agttatcgtg atatatctga
     2461 aatattaagg gaacgtggtg taaacgttca tcattcaaca gtctaccgtt gggttcaaga
     2521 atatgcccca attttgtatc aaatttggaa gaaaaagcat aaaaaagctt attacaaatg
     2581 gcgtattgat gagacgtaca tcaaaataaa aggaaaatgg agctatttat atcgtgccat
     2641 tgatgcagag ggacatacat tagatatttg gttgcgtaag caacgagata atcattcagc
     2701 atatgcgttt atcaaacgtc tcattaaaca atttggtaaa cctcaaaagg taattacaga
     2761 tcaggcacct tcaacgaaag tagcaatagc taaagtaatt aaagctttta aacttaaacc
     2821 tgactgtcat tgtacatcga aatatctgaa taacctcatt gagcaagatc accgtcatat
     2881 taaagtaaga aagacaagat atcaaagtat caatacggca aaaaatacac tcaaaggcat
     2941 tgaatgtatt tacgctctat ataaaaagaa ccgcagatct cttcagatct acggattttc
     3001 gccatgccac gaaattaggg atatgttagc cagttaaggg aacaacgaca tgataaaatg
     3061 gtagttagct atatttttct aactttgcaa cagaaccaga atattcattt aactcctcct
     3121 atatagtgtt ttgcaatatt tacgttttat agattattcc accattcaaa gttatcttgt
     3181 ttaagtaatt gatcgctttc tttaggtcca aaacttcctg gtttatactg tggtattgtt
     3241 acgttagatt ttttccattc agtacttata taatctataa attcccatga ttgtttaagt
     3301 tcttcccaat gtacaaaatt agtttgattt cctattaaag catcacatat aagtgattca
     3361 taagcatcca ctacttggtt tttatctatt gagttataaa ttttcatatt atgacttcta
     3421 ttatttctat ttgatttatt ttcataaata tatagtgata ttttggcatt aggttctata
     3481 tttattacca gtaaattaca atcagtatcc tcattattat tttcatatct taatgtatta
     3541 ttgttttttt tgaattctat aacaatctct gttgcttttt tacctaagcg tttccccgta
     3601 cgaatataaa atggagtccc ttcccatctt ctattattga taagtacttt tcctgctaca
     3661 aatgtttctg ttgttgaatc actatcaaca cctttttctt catgatatga cattatcgga
     3721 gtttcattaa taataccatt aatatattgt cctctaacaa aatatttgtg tacatcagcc
     3781 cctttcaaaa attttatatt gtttaaaagt tcgatttttt ttagtctaat atctttacta
     3841 tttctgcttt cgggtttctc catagcaata agagtaagta tttgtagtgc atgattttgc
     3901 accatatctt taagcgctcc tgtagaatca tagtattggc ctctatcttc aatgcctaaa
     3961 gtttccgata gagttatttg aacatttgat atatacttgt tgttccacaa tggttcaaat
     4021 attgtattac caaaacgtaa agattcaata ttttgcacca tctctttacc tagataatga
     4081 tctattctaa atatttcttc ttctttaaaa tactgtctta tgtgtttatt taagtcttca
     4141 gcagatttca aatcttttcc aaatggtttt tcgattatta atcttgaaaa tccatttgta
     4201 tcagaaagac ctgattggct tatgctttga gttataattt taaaaaattg aggattcatt
     4261 gctaagtaaa ataatctatt gccatccaaa caatattttt tatcaatatc attggaaagt
     4321 tcctttaatt tattccaact tgttttatct tcaacatttt gttgaaagta aaatatgtta
     4381 tctaaaaata agttcaccat ttcaaaattt tctcggctta ataaaatttg ttttacttta
     4441 cttctatatt cttcatcact tatatcctct aaacccgtag aaatgataac taatttctta
     4501 aagtgaccct ttttataaag attaaaaata gaaggtagca atttcctgta acttaaatct
     4561 cctgttccgc caaatattgt tattaatgat gataaatttt tatccaaagc agttcccccc
     4621 ttttacttga ttagctagtt tctggttttc attccgtaac agtaattata ttactcttca
     4681 tcccattgtg tgtggaacac accttcatga tctttacgtt cataagtatg tgcaccaaaa
     4741 tagtcacgtt gtgcttggat aagattagca ggtaaatctt cagaacgata actatcatag
     4801 tagttcacac ttgcagagaa tcctggtgtt ggtacaccgt ttttaacgcc tgttgctacg
     4861 acgtctctta atgcatcttg gtaatctgta acaatatttt tgaagtatgg atctaataat
     4921 aagttttcaa gttctggatt attatcgtaa gcatctttaa ttttttgtaa gaattgtgca
     4981 cgaatgatac aaccttcacg ccaaatcatt gccagttcac ctaattttaa gttccattcg
     5041 tgatcttcgc tcgattttct catttgcgca aagccttgag cgtaagaaca aatcttactc
     5101 atatataatg cttttctgat tttttctaag aattcttctt tattaccatc aaatgaagct
     5161 tgtggtccat ttaatgattt agacgcatta acacgttctt ctttaatgga tgaaatgaaa
     5221 cgagcaaata ccgattcagt gataattgtt aatggaattc ctaattctaa tgcattaata
     5281 gaagtccatt tacctgtacc tttttgacca gcagtatcta atattttttc tactaatggt
     5341 tcattatttt catctaattt agtgaaaata tcaccagtaa tttctattaa gtaactttcg
     5401 agttctccag cattccaatc tttgaatgtt tgagaaattt cagtatgact catacctaat
     5461 aagtctttca tcattgtata actttcagcg attaattgca tatctgcata ttcaataccg
     5521 ttatgaacca ttttcacata atgacctgca ccatttgggc caatgtatgt tacgcaagat
     5581 gcaccatctt gcgctttagc tgcaatggca tctaagatat cactgacttt attataagcg
     5641 gcttcttgac caccaggcat taatgaagga ccagttaaag cgcctacttc accacctgat
     5701 acgcccatac caatgaaatt aacgccactt tcagctaatg ttttatttcg acgaattgta
     5761 tcttgatagt ttgtattacc accatcaatt aaaatatctt catcgtctaa taatggaagt
     5821 aaggcattta tcatgttatc cgtaggacta ccagccttaa tcatcaacaa aattttacgg
     5881 ggtttttcta atgaatctac aaattctttc aagttatacg caggatatat cttttgataa
     5941 tgagactttt gaatagtatc attaatttca ttattatctc tactatgaat actcacagaa
     6001 tatttcttat cctcgatgtt ccacgcaaga tttttcccca taacacctaa acctaaaatt
     6061 ccaatattac tagacattgt atcctctcat ttctttatag tttataacct acaatcttgc
     6121 ttcaagatct tttttcatat cttcaaatcc tggtttacca agtaaagcaa acatattttg
     6181 tttatacgct tctacaccag gttgattgaa tggatttacg cctaattgat aaccactcat
     6241 agcacatgca agttcgaaga agtacacgac atagccaaat gtttcttcat ctaattgtgg
     6301 aatattaaca acgatattag gtacgccacc atctgtatgt gctaataatg taccttcaaa
     6361 tgcttttgta ttaacttcat caattgtttt accagcaaga taatttaatc catctaaatc
     6421 gtcactatct tcttcaatag taagatcatg ttttggatga ttcactttta caactgtttc
     6481 aaataagaaa cgacgacctt cttgaacgta ttgtcctaat gaatgtaaat cagtagtgta
     6541 gttagcactt gaaggataaa tacctttaaa gtctttacct tctgattcac caaataattg
     6601 tttccaccat tcgttgaaat attgcattga cggttcatag ttgataagca tttcagttgt
     6661 ataacctttg ctatatagaa ggttacggat tgttgcatat tgataagcaa tattttcttc
     6721 taatttgtca gaagataatt ctttacgtgc ttttgctgca ccaatcatca tcgcttcaat
     6781 attaatacct gcagctgcga ttggtaataa acctacagca gttaacactg aataacggcc
     6841 acctacatca tcagggacta caaatgtttc ataaccttca tttgtagcta attgttttaa
     6901 tgcacctttt tgtttatctg ttgtagcaaa gatacgtttt ttagcttctt ctttgccata
     6961 tttactctca actaattgtt tgaataaacg gaatgcaact gctggttctg tagttgtacc
     7021 agatttagaa atgacgttta cagagaaatc tttgtcagct aaataatcta ctaattcttt
     7081 tgtatagctt gatgataaat ggttacctac aaaaacaatt tcaggatagt cattatttgt
     7141 tctaaatgaa gatgttagca tttcaatagc agcacgtgca ccaaggtatg agccaccaat
     7201 accaataaca actaacacgt cagaatttgc tttaatacgt ttagaagctt ctacaattct
     7261 tgaaaactct tctttatcat aatcaactgg aaggtctacc caacccaaga aatcatttcc
     7321 tgcaccagtt cctccatgta tcgttttgtg taatgtcttc acgatatctt tttgttgttc
     7381 taattcatgt tctccaaaaa attctaaagt cttaccataa tctaattgaa tatgagtcat
     7441 ctaaaaagcc tccaaatttg taattattag tcttatattt acaattccaa ctgtacacta
     7501 cagtgtaata ttattcatac tgaaaaaata gtcaccccct ttagataagc tgacattccc
     7561 tatatgccaa ttttgtcagt attgatttat tgataattat gtcaaaataa aggtataaat
     7621 taatgaaagg atgaattatc gtggaattac aattagctat tgatttatta aataaagaag
     7681 aagcagcaga attagcgaaa aaagtagaag aatatgttga tattgtagaa attggtacac
     7741 caattgtgat taacgaaggt ttacctgccg ttcaacattt aaatgaaaat ataagcaatg
     7801 ctaaagtatt agcagactta aaaatcatgg atgcagcaga ctatgaagta agccaagctg
     7861 ttaaattcgg cgctgatgtt gtaacaattt taggtgtagc agaagatgcg tcaattaaag
     7921 cagcagttga agaagcacat aaaaataaca aacaattatt agtagatatg attgctgttc
     7981 aagatttaga aaaacgtgcg aaagaattag atgaaatggg tgctgactat attgcagtgc
     8041 acactggtta tgatttacaa gctgaaggac aatctccatt agatagctta cgtaaagtta
     8101 aatcagtaat taaaaattct aaagtcgcag ttgctggtgg tattaaacca gatacaatta
     8161 aagaaattgt tgcagaagaa cctgacttag taattgttgg tggcggtatc gcaaatgctg
     8221 atgaccctgt agaagcagct aaacaatgtc gtgacgctat tgaaggtaaa tagtgatgac
     8281 aacttttaat cattatcaat taattttaga tgagctaaag ggcactttat ctcatgttaa
     8341 agatgaagaa tttgatggat ttgcatcaga agtaactgaa gcatcacgta tatttgttgc
     8401 aggtaagggg cgttctggat ttgttgcaaa tagttttgca atgagactca atcaattagg
     8461 aaagcaagca tttgtcattg gcgaatcaac aacaccatca attcaaaaag atgatttatt
     8521 tattgtgatt tctggttcag gttcaacaga acatcttcgc ttattagcag aaaaagcgaa
     8581 atcagttgat gcaaaagtgg tattactaac aactaaacta gattctgcaa ttggtgaaat
     8641 tgcagacaca gtagttgaat taccagcagg tacaaaacac gatgctactg ggtctgatca
     8701 accgttaggt agtttgtttg aacaatcatc acaaatcttt ttagatagtg tagtcattgg
     8761 actaatgaca caattagatg ttgatgaaac aactatgcaa aataatcatg ccaatttaga
     8821 atagatataa ataagcagtt aatgcggaag attatataat cttccgcatt aacaatgtaa
     8881 attctaatat tatagaagaa agaaggatga aaattgtatt ataaaggaaa agaatttttc
     8941 acttctaaag atttagcttt atgtgttatc ggaggaaagt ggaagatccc tataattttt
     9001 catttacttc aagacaaagt attgagatta agtgagctac aaaaaaagtt gccgcatgtc
     9061 aatcaaagga tgctaataag acaacttaga gaattagaag aggaccaaat tattgaaaga
     9121 catatttatt ctgtagttcc cccaaaagtg gagtataagc tgacatctat aggctacaag
     9181 ctagataagg tggtttatgc aatatgcgaa tggggtgatt tattcaagga tgaaataata
     9241 cattaaaaag ttctggtgca aattaaaaat aaagttaact actctcttat aatgtaagta
     9301 ttcaattagc tgactaacat gtattaattt cgccgttcta tgaaattaag ggttctgttg
     9361 caaagttaga aagatatatc taatcaccat tttattgtgt cagtcttcac ctaaccagct
     9421 aacatataac taatttcgtg gcatggtgaa aatccgtaga tctgaagaga cctacggctc
     9481 tttttatata atccgtaaat acattcaatg cctttgagtg tattttttgc cgtattgaca
     9541 ctttgatatc ttgtctttct tactttaata tgacggtgat cttgctcaat gaggttattc
     9601 agatatttcg atgtacaatg acagtcagga ttcagtttaa acgttttaat gactttagcc
     9661 attgcgacct tcgttgaagg tgcctgatct gtaatcacct tttgaggttt accaaattgt
     9721 ttaatgagac gtttgataaa tgcatatgct gaatgattat ctcgttgctt acgcaaccaa
     9781 atatctaatg tatgaccctc tgcatcaata gcacgatata aatagctcca ttttcctttt
     9841 attttgatgt acgtctcatc aatacgccat ttgtaatagg cttttttatg ttttttcttc
     9901 caaatttgat acaaaatagg agcatattct tgaacccaac gatagactgt tgaatgatga
     9961 acgttgacac cacgttctct tagtatttca gatatatcac gataactcag cgcgtatctt
    10021 agatagtagc caacggctac agtgatgacg tccttgttaa attgtttata tctgaaatag
    10081 ttcatacaga agactccttt ttgttaaaat tatactataa attcaacttt gcaacagaac
    10141 cagatcactt atcagaagct acctatcatc gtatattcgt agatgatata atatacaagt
    10201 cgtctatctc tcaggcgtca attccgacgc agagaggagg tgctaatcta tgctagaaat
    10261 ccttgttcac atcacgacca cagtcatcag tggttgtatt attgcgttat ttacgcattg
    10321 gctacgtaat cgcaataata aataggcgac catagccaca cctaaaaaat cccctcacta
    10381 ttgccgtagt gaggggattg gtgcatctat gctagtttcc ttgttaacta aattataaca
    10441 tcggtgagtg gagaaatgca aagtcctcat tcatttctct tttgaatatt atttctatct
    10501 ataatctaac tcgtctttac ggataaaaac attgtaactt ggcataacat tgtttaactt
    10561 atggttactt ttttgtaaat ctataccaca cttattaagt atagctttca tgataattcg
    10621 atctgattct ttaatatcca tataatcttc agacatattt ttataaggtg aattgacttt
    10681 aaaagtgatt tgtgaaatta aacatgcatt ttcaatactg tccatatgag gatagacgtt
    10741 gcattttata gcagttcctt ttactacact cttttggagc agtaaccaat agttacgtaa
    10801 agattgtagt aaagtgtctt caaatggaat tagtataatc gatgataaaa aaactccgat
    10861 aataaaccaa aatccgttta ctatttagtt gcaaattgct agattcataa gtcacttcgc
    10921 ttcctcaaga attatgattt tattatatca tttttacgct ttcagtttat ttaatattta
    10981 taactttaat tgtatgattg gcgtacaccc taatcataca aaataagttg ttgaaattat
    11041 cgcaattaga acgtatgatt agggtgtata ttaattatgg agtgaagatg aatgattata
    11101 ggttatgcga gagtatcatc gatagatcaa aatttagaaa gacaattgga taatttaaag
    11161 acgtttggtg tggagaaaat ctttacagag aaacagtcgg gaaagtcagt ggaaaataga
    11221 cctgtatttc aagaagcact caattttgtc agaatgggag atcgattcgt tgtggaatct
    11281 attgatcgtt tgggacgtga ttatgatgaa attattgaaa ctgtgagtta tttaaaagag
    11341 aaagacgttc agttaatgat taccagctta cctatgatga atgaagtgat tggcaatcca
    11401 ttactggata agtttatgaa agatttaatc gttcaaattt tagcaatggt ttcagaacaa
    11461 gagagaaatg aaagtaaacg tcgacaagcg caaggaattc aagttgcgaa ggaaaaaggc
    11521 gtatataaag ggcgcccctt actttattca ccaaatgcca aagacccaca gaaacgtatt
    11581 atttatcatc gcgtggtgga aatgttagaa gaagggaaag caattagtaa gattgcgaaa
    11641 gaagttaata tcacaagaca gacagtttat agaattaagc atgataaggg atcatcttga
    11701 taaatgggtc gtcaatgcaa ataagaggct ctcacagagt ctcaaaactc atattatatt
    11761 attgaaatga tcttttaata attatacaag aaaaaagaga gtgcgaattc gcactctctt
    11821 tttgtgtagt aatactattt aaatttttta tcaataatga acgtaattta gaaataatat
    11881 ttattggtat ttcaagaata tatatataat tatttactaa gtccatttaa aaaaatttga
    11941 gagaacttgt tcataagttt aattctttca ttaatatttt gttcatgtgt aaaggtaaca
    12001 attccattaa cagcgtttgc tgctatttta ctaacagcat taacatcatt aatacaccat
    12061 tcgccattta aattaccctc cttaaaaatt acatgataag catctatata tttgttttct
    12121 aatttattca ttttttcatt aatgctatta gttttataat attcagtgca aaattcaatt
    12181 attgcgtttt gaagtggata atagtattcg gttgttaaag atagttcatt atataaataa
    12241 aatttttctc tattagtttt acatttgatt tgttcctttt tccactgttc ttgccattta
    12301 gattcttcta tatttaaaat ttctaaaaat agattttctt ttgttttaaa gtgataataa
    12361 agattccctt tactactttc tgataattta acaatttctc cagtagtagt ggcattatat
    12421 ccatttttta taaataattc ctttgcgaca cctagtattt tatctttcaa gttcatcacg
    12481 cctttaatga gtattaagta ctatcaatga tagcacaaaa attcaaagaa taattgtata
    12541 acacaataca gccatttaaa tttcgcaaga ttttttgttg taatatgtaa aaaaatagat
    12601 tataatcctt atagaccgat cgaacggtct ataaggattg gagggaactt aaatgatttc
    12661 attttttaca aaaactactg atatgatgac atcaaaaaaa agatggactg cactagtagt
    12721 attagctgtt agtttgtttg ttgttacaat ggatatgaca atattaatta tggctttacc
    12781 ggaattagta agagagttag agccttctgg tacccaacag ttatggatag ttgatatata
    12841 ctctcttgtt ttagctggct ttataattcc attgagtgcc tttgctgata aatggggaag
    12901 aaaaaaagca ttattaactg gatttgcttt atttggcctc gtttcattag ctatattttt
    12961 cgcagaaagt gcagagttcg taatagctat tcgattttta cttggtattg caggtgcttt
    13021 aataatgcca actactcttt caatgataag agtaattttt gaaaacccta aagaaagggc
    13081 cactgcatta gctgtatggt caatcgtttc atcgataggt gctgtttttg gaccaattat
    13141 cggaggagct ttacttgagc aattttcatg gcactcggca tttttaatta atgtaccgtt
    13201 tgtgataata gcaattgtag caggtttatt tttattacca gagtctaagt tatcaaaaga
    13261 aaagtctcac tcgtgggata ttccttctac aattttatca attgcaggca tgattggact
    13321 ggtatggagt atcaaagaat tttcaaaaga aggactagca gatattattc catgggttgt
    13381 aatagtatta gcaattacca tgatagtgat atttgttaaa cgtaatttat caagttctga
    13441 tccaatgtta gacgtaagac tttttaaaaa gagatcattt tcagctggta caattgctgc
    13501 atttatgaca atgtttgcaa tgacatctgt tttgttatta gcttcacaat ggttacaggt
    13561 tgtggaagaa ctttctcctt ttaaagctgg cttataccta ttacctatgg caataggaga
    13621 tatggtgttt gcaccaattg cacccggatt agcggcgcga tttggaccga aaatagtgtt
    13681 accttccgga attggaattg cagccattgg catgtttatt atgtatttct ttggtcatcc
    13741 attatcatat tctacaatgg ctttagcatt aattttagtt ggagctggta cggcttcact
    13801 agcagttgca tctgctctaa taatgttaga aacacctaca tcaaaagcag gtaatgcagc
    13861 tgctgttgaa gagtctatgt atgaccttgg aaatgttttt ggtgtagcag tacttggtag
    13921 cctatcttct atgctttatc gtgtattttt agatatttca tctttttcat caaaaggtat
    13981 agttggagat ttagctcatg tagctgaaga atctgtagtg ggcgctgtcg aagtagctaa
    14041 agctacgggg ataaaacagc ttgcaaacga ggctgtaaca tcatttaatg atgcttttgt
    14101 agcaactgct ttagtaggtg ggattatcat gattatcatt tcaatagttg tctatttgtt
    14161 aattcccaaa tcacttgata taactaaaca aaaatagtac taaacatata tttttagata
    14221 ttgtagatta gtttattttt aaaattagta atagttaaaa agtagaacca ttaattttaa
    14281 atggttctac ttttttatta ttaagtaaaa ttataaaaga caatttctta aattaataat
    14341 atgatatacc tatatctaat aatttattag tattaataaa ccttgaaagg atgattaact
    14401 gatgaataga gcagatattt ttaaaatatt tgatgtagaa cttaatataa ctatattttt
    14461 aggagcacta gtagcaactt tcatctattt tataagttac atgaacaatg taaatgaatt
    14521 aattacatta tgcttaacat tagcttttcc tgcatattta ttaaaaatta gcagatcgtt
    14581 cgaggttatt ttattagagg aaaaaataaa aaatagtaaa atcaaaatct gtgacaaaga
    14641 tagaattgaa cgagagatac tggtgaaaaa gaacctaata gatgaactat tgtttcctaa
    14701 tagagttatt aaaaaatata cactgacaat tttaatttac agtataggta ttattattct
    14761 tttactactt tgtaatatgt taagttatgg aattggtgaa aatgtcaatt ttatctggag
    14821 attactagct tgttatgtaa cgagtgtcac agtgattata gttgccttga ttataatgat
    14881 aatgatattt gatcttataa ttggattact attaaatttt caaatatttt taaaaaataa
    14941 aaagtatgat gactttttat aattattcga tttatataat gaaaaattaa atgattaaac
    15001 atagaaacct caaaacaaac catatttaat agagtttatg gcgccttata caaataaagg
    15061 ctatgctgtt aaagaattat gtagctatct tcagattaat atggatgatg tttatactat
    15121 tggcgataga aaattgattt acctatgttt aataccctag ataattcttc tgataattta
    15181 gtttttgtta gagtttaaca taactgatga ttaccagaag ttctcactat ataaaagaca
    15241 ctaaaatttt ataactttta gtgcctaatc aattatttta gctaccaaac aaacgactcc
    15301 aaaacccctt tttaggttcc gtttcttcac tcttttcttc tatatcacta tcattgtcat
    15361 ttagattagc tggaacgtct tctttttttg cttcttcacc ttgtgtactt tcgtcgcttt
    15421 gacttccaga tatatcctta tattgaatct ctgtttcttt agtttcttcc tgatctctgt
    15481 taatatttac aggattagta gtatatgttt tttcttgtgc atcaacgttt tgtctagtgt
    15541 tagtagatgt atcaaaggga taattaaggt gtttttcttt ttctaattga ttttctaatt
    15601 tttgaatctt tttattactc tctaatgcca gaacttgctg attttcaagc aattttgatc
    15661 tttcttgcaa ctcttttctg taaaattcaa ttgttgtttc atgacgactt tcttgttttt
    15721 caatttgatt atttaaagta tcaatctgat ttttaaggat ttctactatt tgagcatcgc
    15781 ttttcgattc aaaattaata ttatccgacc cttttttttg tttgtcttca gtagtacttt
    15841 caaaaccata tttcttttta ttttcattta ctctttgaat gattttttct atatcggtat
    15901 cttctttaat aaacgaagtg ttttcctgtt ttattgtctc tatattcaat cgcttaatat
    15961 tattaaaaat cgtttgctta ctaaccccta attcttcact caactttttc acacttttca
    16021 tatcatcaac cctttataaa atgtttataa acccttgata aaatattata agcttataat
    16081 gcttaataat aaagtgatta ataaataaaa ataaacatcc atcaaccttt ttatcaaggg
    16141 tttatgaaag gtttatgata tttatcaagg gtttataaac ccttgataaa gctatatttt
    16201 cccttttata agtttattta aagtgctata ataaacttaa tataacaaaa accccaacta
    16261 ctggtaatag tcggggtttg gtaataaaac gtttagaaac tgtttattta tataattttc
    16321 gatacttgta ttatataatg aataatatct tagtgcaagc acctaaatca ttaaataaat
    16381 gtaaagctaa ataaaaacgt tttattacct cttaccaaac taaaatatgg aaagaggttt
    16441 tttgtcatgc aaaatcaata ttttacagtg caagaaaatt acaaagaaag attttatcaa
    16501 atccctaaag tattctttac cagtgaaaat tataaaaatc taactaatga tatgaaaata
    16561 gcctatgcta tcttacgtga tcgcttaaat ttatctatta aaaatagctg ggttgatgaa
    16621 gatggtaaca tttactttgt ttattcaaat gaaaagctaa tggaaatctt aaattgtaaa
    16681 aaagaaaagt taacaaaaat aaaaaaaggg ttagaaaacg atggtctact cattcaaaaa
    16741 cgacgtggtt taaataaacc aaatattcta tatttaatga aacctattgt cacagaacgt
    16801 gatatttaca aaatagaaaa agaagaaaac gatgttgaac cttacggcga gaaggaagtt
    16861 cgaaaatcga acgtccagaa gttcgaaaat cgaacgtcca gaagttcgaa aatcgaacgt
    16921 ccagaagttc gaaaatcgaa cactaatgat actgacttta atgacattga ctttaatgat
    16981 actgagaata atgatatgaa tgacttgaat gatataaagt acaaaaatga aattagtaat
    17041 cattcaaatc attcaaatca atttacacat aattttgatg ataaagaaat gctattgcaa
    17101 gaattcccag aacaactaac taattattta ttaaaatatg attatagaga tttagaaatc
    17161 ataaaggctg ttattcttaa agcaaaaaaa tcatttaatt caaggcatga agatatgcat
    17221 tacatgttag aggacattga ggatgaaata ttaacttctt taaaaagact taaaaaagct
    17281 atacatgata ggggagttaa aggccaaaag gaaacaatca agtcaatgca agcttattta
    17341 atgcaaacaa ttctaactga acttgaagaa acacatgccc tttatatgcg ccgtaaaaac
    17401 atgaaacaat ataatatctt taatcaataa ttcaaatgat tttataacac tcgaagagac
    17461 atcaaaatat tccgttaaat catctgactt tttaactgat gacgacgaaa aaaatcaaga
    17521 aattgtaagt gatttagaaa aaggtttgta tcgaaaacgt atgttaagtt atggtggatt
    17581 gcttaaacaa aagcataaaa ttttaaactt agacgatgcc gaagatggta atttgattaa
    17641 tacaagtgat gaagataaaa cgacagacga agaaaaaaag cacattcaat taccgcaatt
    17701 tggaatttcg aaaagcaaaa ttattattta agacattagt gataactgat gtcttttttt
    17761 attgtttttc tgtaaaaaag tgctgtctta tttttgtgac aaatgctgta tgtagtgtca
    17821 caaaagtgtg acactacagc tttgtatgat atcactttaa aataacttaa aacccttgga
    17881 atgtctggcc ttgccagatc tatcattttt gaatgatagc aaatttccct tatgctctta
    17941 cggagatttt agagttaaat taaaatttct aagtttttga taagaaaagc cctgcaggaa
    18001 tttagaaaaa catggggaag ttttaaagta ttttatgcta atttttaaat ttgcatgtaa
    18061 atgggcagta tctaaaaaat tagtcactga ttttgctgaa atttttgttt gtgaaattag
    18121 catatattta tttggctcat atttgcgttt taagagactg tatagatttt taagtacaaa
    18181 acctatatga tttgcctcta agtcttcaaa atgcctctta aaatccaaaa taaaagtgtt
    18241 taatattgta ataaggattg ctatttttat aaaaggagag atatcatgaa gattaaaact
    18301 ttcgctactt ttactcatcg tcaattagat aaacaagtta ataggttttt aaagaatgat
    18361 attcatgtat tagaaattca aacacacagt aattggttat atatttcagc tattgttttt
    18421 tatgaggata aataaggaac atcgtattta tgccgaaaaa atttattgat gttgagaaga
    18481 acccttaact aaacttgcag acgaatgtcg gcatagcgtg agctattaag ccgaccattc
    18541 gacaagtttt gggattgtta agggttccga ggctcaacgt caataaaaca attggaataa
    18601 aatcaaccta cagagcatcc agctgcaaat gcagttccgc aaactgcttc acatacaccg
    18661 ccggctattg gatttacgat tgcccatact ccacagtagt gagcacatgc ataaagtcca
    18721 gccatactac aagcgaatgc tttgccgttc catttgaatc ctgcatatgt taccggtctg
    18781 tttttatcaa ctttttcagc cttatattca acgtaatttt tgttaataag tatttttccc
    18841 tctttgtttt cagtcatact tcttttttcg gcaatgaatt ttgtgatttt tttgttgtag
    18901 ttatcatata ttgtttcaga aactacaatt tcttttgttt tttcattttt ataagcgtta
    18961 ttagctatgt agccatatgc atttttatca tttgcttctg tagctagata ttttaattta
    19021 gaatttttgt cttctagctt tattttttta aatccttctt ttttcatttg cttttcgaat
    19081 ttttgcatat cttcattttt attttgcaat tgttctagaa aacttatttc tttcttggtc
    19141 atttgtgata cttcgatgtt tttgcttttc aatttttctt tttgattttc tagtaaagaa
    19201 cttttttgtt cttcatttgc gtaagcatta gaaaaattcg cgctaaatac cagtaggaac
    19261 aaggaaatta ttgaaaataa ttttataatt ttcatttgat acctccaaga taataagata
    19321 ttttaattgt ataagtaagc gctttataaa atcaatattt attttaatat atttataaac
    19381 atatttttga aaggagtcta ttttatgaat gaaaatttag aaaaatatat aaaaagtttg
    19441 ccacttttag gtttgttaat tagtattttg ttaattgttt tattcttttt tattttagat
    19501 gttgatgaag atttattcgt ggttttttta tactgtttat tgcctttgat agttaatttg
    19561 tctatttatg gtttttatgt ttttgttaaa agaaagtaag attatgaata attttgtttt
    19621 taatttgtat gctttgaggg ggttggaaaa cggtaggtgt atagattaga tttcttgttt
    19681 ttttgaaacg agtgtgaacg agtttcttct tgtcttgatt tttgataaaa acgccctaca
    19741 ggaatttaga aaaacgtggg gaagttttaa agaattttat gctaattttt aatttgcatg
    19801 taaatgggca gtgtctaaaa atagttattg tttttgctca aatttttgtt tttgaaaata
    19861 gcatatattt atttggctca tatttgcgtt ttaaaagcat atataagttt tagatataaa
    19921 actatatgaa tcacccctaa atctttaaaa tgccctctta aaattcaaaa taagggcata
    19981 aaaaataaaa gctaccccag ataaagtgag gtagcttttt ctttcatacg gtctatttat
    20041 ttttctttcg acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca
    20101 tcactttttc aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg
    20161 aatatctcaa gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt
    20221 tttgcacatg tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat
    20281 aacgacgaat tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt
    20341 acaaaataga accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa
    20401 taaacttcct aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc
    20461 tgaagtgtct ccatgtctac gcatagacac gcatttatgc cgaaaaaatt tattgatgtt
    20521 gagaagaacc cttaactaaa cttgcagacg aatgtcggca tagcgtgagc tattaagccg
    20581 accattcgac aagttttggg attgttaagg gttccgaggc tcaacgtcaa taaagcaatt
    20641 ggaataaagc acctatgatt atttaaaaat ataagttata atacattcaa aaatattttt
    20701 gaatgaggtg tattatgatt caaacggttg ttgctgctgc tgttctttat attgctacag
    20761 cagttgattt attagtaatt ttattaatat tttttgctag agcaaagact agaaaagaat
    20821 atagagatat ttatgttggt caatatttag ggtctattat tttaatatta gttagtttgt
    20881 ttttagcttt tgtattaaat tatgttccag aaaagtggat attaggttta ttgggtttaa
    20941 taccaattta tcttggaatt aaagtggcta tttatgatga ttgtgaagga gaaaagagag
    21001 ctaaaaaaga attgaatgaa aaaggattgt ctaaattagt tggtacggtt gcaattgtta
    21061 cgatagcaag ttgtggcgcc gataatattg gtttatttgt tccgtatttt gtgacattaa
    21121 gtgttactaa tttattactt actctgtttg tctttttaat tttaattttc ttcttggtgt
    21181 ttactgcaca aaaattagct aatattccag gaattggaga aattgttgag aaatttagtc
    21241 gttggattat ggctattatt tatatagctt taggtttatt tattattatt gaaaatgaca
    21301 ctattcaaac aattttagga tttatatttt aatttagggt gtgattttat atgagttatg
    21361 aaaatacttg tgatgtgatc tgtgtacatg aggataaagt taacaatgct ttaagttttt
    21421 tagaagatga taaatctaag aaattactta acattttaga aaaaatttgt gatgagaaga
    21481 aattgaaaat catattatct ttgattaaag aagatgagtt gtgtgtttgt gatatttctt
    21541 tgatattgaa aatgagtgtt gcttcaactt cacatcattt aaggctttta tataaaaatg
    21601 aggtacttga tttttataaa gatggaaaga tggcatatta ttttattaaa gacgatgaaa
    21661 taagagagtt tttctctaaa aatcatgagg gtttttgaaa cgagtttctt cttgtcttga
    21721 tactataaaa aacaaagtta tataacataa gacgacttat cggaagtaga tatgcttgta
    21781 tattcacaga tggtataata atagagtcgc ctatctctca ggcgtcaatt gacgaagaga
    21841 ggaggtgcat tactttgcta atcattttcg ttcacatcat agcaccagtc atcagtggct
    21901 gtgctgttgc gtattatact tattggctta gtaaacgcaa caaataatta ataggcgact
    21961 ttataagcca gcatcgaaaa aatccccaca ctactgcaat agtgtgggga ttggtgcatt
    22021 aattgttaat cattttcgtt atataaatta taacactggt tagtagagaa atgcaaaatg
    22081 attgaattaa tagtaaatgt attaatgaat actcacactt atacttttaa aatagttctt
    22141 cctaaatgtt gtccttttaa aagctgatct atcgttttat agaattcttc aaatccaatt
    22201 tcattgtata gaagtgaatt tcctatattc cattcatttg ctaacttact ccatatatct
    22261 tcacggatat tatgatcaac atatacagaa tcaatgccaa ttaatttaat acctctaaga
    22321 ataaacggta atatattagc gttaagtgaa tttcctgcta catttccaca tacagtagca
    22381 acaccttgat aatttagacg ttttaaaccg tataatgtta cattactccc cactgtatct
    22441 aagaaataat caaaaatacc ttttttaagc ggtttattat catcttcaat tattattact
    22501 tgttttgcac ctaatttttt tgcgatttct atttgctttt cttttcttac gatagcagtg
    22561 atattttcat atccaatttt atgtaaaatt tgtatagcaa cactgcccac accacctgta
    22621 gccccagaca ctaaaatttc aggttgtgat ttgatattca ttccatattt ttctagttca
    22681 aaaattgata atgctgccgt aaaaccggct gtgccatata ccatagactc tttaatagac
    22741 atttcttggg gaataggaac aatccactct ccaggcactt gtgcatattc tgaaaatcca
    22801 cctgtatgtg tcacgccaac atcataacca gtaactaata cattatcgcc ttctttaaac
    22861 ttatcattcg aacttgattc aacaatacct gcaaaatcta taccaggaat cataggataa
    22921 tctctaatta caccgccttt atattgtaaa gctagcatat ccttataatt tattgaagag
    22981 tataccactt ttactaatac atcacccttc gataaatgag attcatcaac tttttctact
    23041 ttataactaa catttgatgc actttttctc actactaccg cattgaacat ttattagcct
    23101 tctttcacaa ttgttttgta gaagtatgtt tttgttgcaa aactattttc ctacaaaact
    23161 tatcatgata tgataagcga gtcaatacta atgatttaag agaggtttta gttgtggaat
    23221 tagataattg tataaattat ttgttgagta cttctcagaa tagagttttt aaacatttta
    23281 aaagtttatt aagtccctat aatattactc cagcagaata tggtgttttg aattgcttga
    23341 ttaatagtaa tttgaataca cctaaagcga ttggtaatac tttaaattta gaaccttcaa
    23401 caatatctgg aatattagat aagatgtcca aaaaggatct aataacacgt caaactgata
    23461 atgaaaatag aagaactgtg ctaataaaca gtacaaataa agcaaaagac ttatggccaa
    23521 cattagaaaa gaaagcctat caacttaata atcattactt cgctaattta actaatgaag
    23581 aaactgtagt gtttaaaaag atattactaa agataaataa aactacgttt taatttttac
    23641 gttataaaaa agttgaagtg cgaattataa tcgagtaaat ataaatgata gcttagctta
    23701 attatatatt aaagccaact atacttttat tcccgaaaaa cctactatcc aaatttctaa
    23761 gatactttag cctctataat aaacatattg taatataatt tatgtattat ttaggtttac
    23821 cctaatcgaa caataaaaaa tacttgtaaa atgctattgt cactttgctt gatatatgag
    23881 aattatttaa ccttataaat gagaaaaaag caacgcactt taaataagat acgttgcttt
    23941 ttcgattgat gaatacctat aattaaacta ttcatctatt atttatgatt ttttgtatat
    24001 acaatatttc tagtttgtta aagagaatta agaaaataaa tatcgaaaat aatagaggga
    24061 aaatcagttt ttgatatcaa aattatacat gtcaacgata atacaaacta taagatgata
    24121 tcagtattta ttatgcattt agaatattaa aattccttca ttacactctt ggcggtttca
    24181 cttatcaact tatcatttgg cttatcactt ttattgtctt tattcgtaaa aatgactaaa
    24241 acaataggtt cagattggcc cttaggataa acaaaagcaa catcatttct agaagcatat
    24301 gttattgctt gaccactttt atcagcaacc ttacagtctt ttgaaacacc gtctttaatt
    24361 aaagtatctc cgcttttatt atttaacatt aaatcaagta agaatttttt gttttctttg
    24421 cttaattttc catttgcgat aagtttattt aaagtcttac cgaaagcagc aggtgttgaa
    24481 gtatcttttt tgctctttgg tgaataataa tttaattcta tctcatatct aactggattt
    24541 gttactttat ctcctagtcc ttttagacgt tgtttaactt ttttgatccc accgatctct
    24601 tttataattt tattgtttgc tgtattatca ctatatgcca ttgaagcctc aataagttct
    24661 tttaaagtga tatcttttcc tacatatttt tctaaaatag gagaataagc aactatatca
    24721 tctttgttaa tatgtatttt tttatttaac ttattataag gtacttgttc taacaaaata
    24781 gcactattta tcgcttttga agtcgaagca taggcaaatc tcttatctga attaaatttt
    24841 acttccttac cacttttagt atctaaagca taaacaccaa tatgagcatt atattttttt
    24901 tctaaatcat ttaactcttt ggcatgtgaa ctgtttgaat tacatgcact taaaactaaa
    24961 gcaattacaa ttaaaaatat taactttttc aaaataaacc ctccgatatt acagttgtaa
    25021 tttttataaa tcaataatat tacaattgta atattgatgt caattgttta ttataaatat
    25081 ttgaaagaag gtgtcaaaat ggctaaatta ctaataatga gcgtagtaag cttttgtttt
    25141 atatttctat tgttagtatt ttttaggtac atattaaaac gctattttaa ttatagttta
    25201 aattataaag tttggtatct aactatgctt gctggattaa ttccttttat cccaattaaa
    25261 ttctctttta taaaatttaa taatgtgaat aatcaagcgc ccacagttga aagtaagtca
    25321 cacgatttga accataacat aaataccacc aaacctattc aagagttcac aacagatatc
    25381 cataagttta attgggattc aattgataat atctgcacag ttatttggat agttttagtt
    25441 attattttaa gttttaaatt tttgaaagcc ttattatatc ttaaatattt aaagaaacag
    25501 tcactttatc taaacgaaaa tgaaaaaaat aaaatagata cgatactttt caaccatcaa
    25561 tataaaaaaa atattgtgat tcgaaaagca gaggctattc aatctccaat aactttttgg
    25621 tatgggaaat atattatttt gattcctagt tcatatttta aaagtgtaat tgataaaaga
    25681 ctaaaatata taatactgca tgaatatgct catgctaaaa atagagatac tttacattta
    25741 attatcttta atatcttctc tattgttatg agttacaatc cattaataca tattgtaaaa
    25801 agaaagataa ttcatgacaa tgaagtagaa gctgatagat ttgttcttaa taatattaac
    25861 aaaaatgaat ttaaaactta tgcggaatct attatggact ccgtattaaa tattccattt
    25921 tttaataaaa atatattaag ccattcattt aatggtaaaa agtcattact caaaagaaga
    25981 ttaattaata taaaagaagc caatttgaaa aaacagtcta aattaattcc aatttttatt
    26041 tgtattttta cttttttgct catagtaatt caaagccagt ttttgatggg gcaatccata
    26101 actgattata attataaaaa gcccttacag aacgatcacc aaattttaga tgaaagtaaa
    26161 aattttggtt caaatagtgg atctttcgtc atgtacagca tgaagaaaga caaatactat
    26221 atttataatg aaaaagaaag tagaaaaaga tattctcctg attcaactta taaaatttat
    26281 ttagcgatgt ttggacttga ccgtcatatc ataagtgata aaaattcacg tatgtcatgg
    26341 aatcataaac attatccttt cgagtcttgg aataaggaac aagatttaaa tacagcaatg
    26401 caaaattcag ttaattggta cttcgaacgt attagtaatc aaataccaaa gaactatact
    26461 gcggctcaac tcaagcaatt aaattatggt aatgaaaatt tgggaagtta taaaaactat
    26521 tggatggaag atagtttgaa aatatctaat cttgaacaag taatagtttt taaaaatatg
    26581 atggaacaaa ataaccattt tagtaaaaaa gcaaagaatc aattatcttc ttcattattg
    26641 attaagaaaa atgaaaagta tgaactgtat gggaaaacag gtacaggtat agtaaacggg
    26701 aagtataata atgggtggtt tgtaggttac gtaattacaa atcatgataa gtattatttt
    26761 gctacacatt tatcagatgg aaacccgtct gggaaaaatg ctgaattaat cagtgaaaaa
    26821 atattaaaag aaatgggtgt tttaaatggc caataagcaa gttgaaatat ctatggctga
    26881 atgggatgtt atgaatataa tatgggataa aaaatcagta tcagctaatg aaattgtagt
    26941 tgaaattcaa aaatataaag aagttagcga taaaacaatt agaacattaa tcacaagact
    27001 atataaaaaa gagattataa aacgatacaa atcagagaat atttattttt actcatcaaa
    27061 tattaaagaa gacgatatta aaatgaaaac tgctaaaact tttcttaata aactgtatgg
    27121 aggggacatg aaaagtttag tgctaaattt tgcgaaaaat gaagaattaa ataacaaaga
    27181 aattgaagaa ttgcgagaca ttttaaatga tattagtaaa aagtaattag agatatgttt
    27241 caaacattat acatatgtaa actatacttg actcttatta aattagtttt gttaataaca
    27301 tttaaaatat attagtaaag atgagagtgt acagaaaata accattttct gtacactctc
    27361 tttttatgtc taaataagta tgtattacat agaattatgt gttcaaaaac ccaacaaaaa
    27421 atctatgttc acaaaagacc tcgtaatcaa gttatggtac actaaaggtg tatataggag
    27481 gtctgtattt tgaaaatagg ttatgcaaga gtttcaactg gattacaaaa tttgaattta
    27541 caggaggatc gattaaatac atatggttgt gaaaagatat ttaatgacca tatgagtggt
    27601 tcaaaaagta agcgacctgg tttagataaa gcaattgaat ttgcgaggtc aggagatacg
    27661 attgttgttt ggagattaga tagactagga cggaacatgg aggatttaat cacgttagtt
    27721 aatgaactta acgaacgagg tgtgagtttt catagtttag aagaaaatat aacgatggat
    27781 aaatcaagtt ctacaggaca attattattt catttattcg cagcatttgc agagtttgaa
    27841 cgtaatttaa ttttagagcg atcatcagcc ggtcgaattg cagcacgtgc tagaggccga
    27901 tatggaggta gacctgaaaa attaaataaa caagatttaa acttacttaa gacactttat
    27961 gataatggta cgccaattaa aacaattgca gagcagtggc aagtttcacg tacaactatt
    28021 tatcgttatc tcaataaatt agaggcaaaa gagaataaaa acaagtagag caactaatct
    28081 agcttactat aatgaatcta ctaaataatt ttatatatca ttaacataca aagactttga
    28141 ttcaatgtca ctcgatgtaa aagagacgtt ctgacagcgt ctaaaatctc ataatatttt
    28201 cctgttatga gattttaata ataacacaag aaaaaagcgt acaaattcgt acgctttttt
    28261 aatataatac ctgtttcact aatgaacgtt ttaagtatct tcatcattaa ctgaaactac
    28321 agtaataata ctcgtcaaca atattagtat agttaaaata gaaagactta ggactggcat
    28381 aaccgaacta aaattatatt tgaaatataa aagtgctaat gaagagagaa atgtaaaaat
    28441 aataaatacc aaagaccatt tttctaattt attcattggc ttcacctctt tgaactttta
    28501 tataatcata ggagatattt ttactacgat ttataaaaaa taagaagata atcattatta
    28561 aagaaacgat taatataatg ttgaatccta tagtatcacc taattcgttt acacctttgc
    28621 ctaatatcgg agatacaaag ctttgtatta ataatgaaag agatgcccat atagtaaatg
    28681 aggttctgtt gcaaagttga atttatagta taattttaac aaaaaggagt cttctgtatg
    28741 aactatttca gatataaaca atttaacaaa gatgttatca ctgtagccgt tggctactat
    28801 ctaagatatg cattgagtta tcgtgatata tctgaaatat taagggaacg tggtgtaaac
    28861 gttcatcatt caacagtcta ccgttgggtt caagaatatg ccccaatttt gtatcaaatt
    28921 tggaagaaaa agcataaaaa agcttattac aaatggcgta ttgatgagac gtacatcaaa
    28981 ataaaaggaa aatggagcta tttatatcgt gccattgatg cagagggaca tacattagat
    29041 atttggttgc gtaagcaacg agataatcat tcagcatatg cgtttatcaa acgtctcatt
    29101 aaacaatttg gtaaacctca aaaggtaatt acagatcagg caccttcaac gaaagtagca
    29161 atagctaaag taattaaagc ttttaaactt aaacctgact gtcattgtac atcgaaatat
    29221 ctgaataacc tcattgagca agatcaccgt catattaaag taagaaagac aagatatcaa
    29281 agtatcaata cggcaaaaaa tacactcaaa ggcattgaat gtatttacgc tctatataaa
    29341 aagaaccgca gatctcttca gatctacgga ttttcgccat gccacgaaat tagggatatg
    29401 ttagccagtt aa
//
