LOCUS       CP152456               26375 bp    DNA     circular BCT 01-MAY-2024
DEFINITION  Staphylococcus aureus strain BSN169 plasmid pSAP027A, complete
            sequence.
ACCESSION   CP152456
VERSION     CP152456.1
DBLINK      BioProject: PRJNA1048360
            BioSample: SAMN38637749
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 26375)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN169 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26375)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN169
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: AP017320, GQ900388, MH660279
            Genome Coverage                   :: 153.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/25/2024 11:37:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,004
            CDSs (total)                      :: 2,925
            Genes (coding)                    :: 2,840
            CDSs (with protein)               :: 2,840
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 47 of 85
            Pseudo Genes (incomplete)         :: 40 of 85
            Pseudo Genes (internal stop)      :: 31 of 85
            Pseudo Genes (multiple problems)  :: 31 of 85
            ##Genome-Annotation-Data-END##
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..26375
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN169"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSAP027A"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-11-20"
                     /collected_by="Andrew D. Berti"
     gene            complement(110..1570)
                     /gene="zwf"
                     /locus_tag="UXQ66_14875"
     CDS             complement(110..1570)
                     /gene="zwf"
                     /locus_tag="UXQ66_14875"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004345 - glucose-6-phosphate dehydrogenase activity
                     [Evidence IEA]; GO_process: GO:0006098 - pentose-phosphate
                     shunt [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="XAH93218.1"
                     /translation="MDKNLSSLITIFGGTGDLSYRKLLPSIFNLYKKGHFKKLVIISTG
                     LEDISDEEYRSKVKQILLSRENFEMVNLFLDNIFYFQQNVEDKTSWNKLKELSNDIDKK
                     YCLDGNRLFYLAMNPQFFKIITQSISQSGLSDTNGFSRLIIEKPFGKDLKSAEDLNKHI
                     RQYFKEEEIFRIDHYLGKEMVQNIESLRFGNTIFEPLWNNKYISNVQITLSETLGIEDR
                     GQYYDSTGALKDMVQNHALQILTLIAMEKPESRNSKDIRLKKIELLNNIKFLKGADVHK
                     YFVRGQYINGIINETPIMSYHEEKGVDSDSTTETFVAGKVLINNRRWEGTPFYIRTGKR
                     LGKKATEIVIEFKKNNNTLRYENNNEDTDCNLLVINIEPNAKISLYIYENKSNRNNRSH
                     NMKIYNSIDKNQVVDAYESLICDALIGNQTNFVHWEELKQSWEFIDYISTEWKKSNVTI
                     PQYKPGSFGPKESDQLLKQDNFEWWNNL"
                     /name="zwf"
     gene            complement(1634..3040)
                     /gene="gndA"
                     /locus_tag="UXQ66_14880"
     CDS             complement(1634..3040)
                     /gene="gndA"
                     /locus_tag="UXQ66_14880"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]; GO_function:
                     GO:0050661 - NADP binding [Evidence IEA]; GO_process:
                     GO:0006098 - pentose-phosphate shunt [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="XAH93219.1"
                     /translation="MSSNIGILGLGVMGKNLAWNIEDKKYSVSIHSRDNNEINDTIQKS
                     HYQKIYPAYNLKEFVDSLEKPRKILLMIKAGSPTDNMINALLPLLDDEDILIDGGNTNY
                     QDTIRRNKTLAESGVNFIGMGVSGGEVGALTGPSLMPGGQEAAYNKVSDILDAIAAKAQ
                     DGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYTMMKDLLGMSHTEISQTFKDWN
                     AGELESYLIEITGDIFTKLDENNEPLVEKILDTAGQKGTGKWTSINALELGIPLTIITE
                     SVFARFISSIKEERVNASKSLNGPQASFDGNKEEFLEKIRKALYMSKICSYAQGFAQMR
                     KSSEDHEWNLKLGELAMIWREGCIIRAQFLQKIKDAYDNNPELENLLLDPYFKNIVTDY
                     QDALRDVVATGVKNGVPTPGFSASVNYYDSYRSEDLPANLIQAQRDYFGAHTYERKDHE
                     GVFHTQWDEE"
                     /name="gndA"
     gene            complement(3072..4403)
                     /locus_tag="UXQ66_14885"
     CDS             complement(3072..4403)
                     /locus_tag="UXQ66_14885"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004347 - glucose-6-phosphate isomerase activity
                     [Evidence IEA]; GO_process: GO:0006096 - glycolytic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="XAH93220.1"
                     /translation="MTHIQLDYGKTLEFFGEHELEQQKDIVKTLHKTIHGGTGAGNDFL
                     GWVDLPVDYDKEEFSRIVEASKRIKANSDVLVVIGIGGSYLGARAAIEMLTSSFRTNND
                     YPEIVFVGNHLSSSYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVESKYGK
                     EEAKKRIFATTDKQKGALKQLATNEGYETFVVPDDVGGRYSVLTAVGLLPIAAAGINIE
                     AMMIGAAKARKELSSDKLEENIAYQYATIRNLLYSKGYTTEMLINYEPSMQYFNEWWKQ
                     LFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKHDLTIEEDSD
                     DLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNIVVNIPQLDEETFGYVVYFFELAC
                     AMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDMKKDLEARL"
                     /name="glucose-6-phosphate isomerase"
     gene            4604..5236
                     /gene="hxlA"
                     /locus_tag="UXQ66_14890"
     CDS             4604..5236
                     /gene="hxlA"
                     /locus_tag="UXQ66_14890"
                     /EC_number="4.1.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0043801 - hexulose-6-phosphate synthase activity
                     [Evidence IEA]; GO_process: GO:0019647 - formaldehyde
                     assimilation via ribulose monophosphate cycle [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="XAH93221.1"
                     /translation="MELQLAIDLLNKEEAAELAKKVEEYVDIVEIGTPIVINEGLPAVQ
                     HLNENISNAKVLADLKIMDAADYEVSQAVKFGADVVTILGVAEDASIKAAVEEAHKNNK
                     QLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLDSLRKVKSVIKNSKVA
                     VAGGIKPDTIKEIVAEEPDLVIVGGGIANADDPVEAAKQCRDAIEGK"
                     /name="hxlA"
     gene            5239..5787
                     /gene="hxlB"
                     /locus_tag="UXQ66_14895"
     CDS             5239..5787
                     /gene="hxlB"
                     /locus_tag="UXQ66_14895"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0043800 - hexulose-6-phosphate isomerase activity
                     [Evidence IEA]; GO_process: GO:1901135 - carbohydrate
                     derivative metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="XAH93222.1"
                     /translation="MTTFNHYQLILDELKGTLSHVKDEEFDGFASEVTEASRIFVAGKG
                     RSGFVANSFAMRLNQLGKQAFVIGESTTPSIQKDDLFIVISGSGSTEHLRLLAEKAKSV
                     DAKVVLLTTKLDSAIGEIADTVVELPAGTKHDATGSDQPLGSLFEQSSQIFLDSVVIGL
                     MTQLDVDETTMQNNHANLE"
                     /name="hxlB"
     gene            5877..6209
                     /locus_tag="UXQ66_14900"
     CDS             5877..6209
                     /locus_tag="UXQ66_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="XAH93223.1"
                     /translation="MYYKGKEFFTSKDLALCVIGGKWKIPIIFHLLQDKVLRLSELQKK
                     LPHVNQRMLIRQLRELEEDQIIERHIYSVVPPKVEYKLTSIGYKLDKVVYAICEWGDLF
                     KDEIIH"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(6374..7048)
                     /locus_tag="UXQ66_14905"
     CDS             complement(6374..7048)
                     /locus_tag="UXQ66_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="XAH93224.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAIAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSVNTAKNTLKGIECIYGLYKKSRRSLQIYGFSPCHEISYML
                     AG"
                     /name="IS6 family transposase"
     gene            7310..7495
                     /locus_tag="UXQ66_14910"
     CDS             7310..7495
                     /locus_tag="UXQ66_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH93225.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(7718..8296)
                     /locus_tag="UXQ66_14915"
     CDS             complement(7718..8296)
                     /locus_tag="UXQ66_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAH93226.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(8560..8940)
                     /gene="blaI"
                     /locus_tag="UXQ66_14920"
     ARG             complement(8564..8940)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8930..10687)
                     /gene="blaR1"
                     /locus_tag="UXQ66_14925"
     ARG             complement(8934..10687)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            10794..11639
                     /gene="blaZ"
                     /locus_tag="UXQ66_14930"
     ARG             10795..11636
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            complement(12153..12572)
                     /locus_tag="UXQ66_14935"
     CDS             complement(12153..12572)
                     /locus_tag="UXQ66_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="XAH93230.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            12696..13667
                     /locus_tag="UXQ66_14940"
     CDS             12696..13667
                     /locus_tag="UXQ66_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="XAH93231.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(13839..13931)
                     /locus_tag="UXQ66_14945"
     CDS             complement(13839..13931)
                     /locus_tag="UXQ66_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAH93203.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(14088..14435)
                     /locus_tag="UXQ66_14950"
     CDS             complement(14088..14435)
                     /locus_tag="UXQ66_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="XAH93204.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(14454..15071)
                     /gene="cadD"
                     /locus_tag="UXQ66_14955"
     ARG             complement(14458..15071)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16187..16381)
                     /locus_tag="UXQ66_14960"
     CDS             complement(16187..16381)
                     /locus_tag="UXQ66_14960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH93206.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            16491..17183
                     /locus_tag="UXQ66_14965"
     CDS             16491..17183
                     /locus_tag="UXQ66_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="XAH93207.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(17351..17500)
                     /locus_tag="UXQ66_14970"
     CDS             complement(17351..17500)
                     /locus_tag="UXQ66_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH93208.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(18047..18336)
                     /locus_tag="UXQ66_14975"
                     /pseudo=""
     CDS             complement(18047..18336)
                     /locus_tag="UXQ66_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(18356..19339)
                     /locus_tag="UXQ66_14980"
     CDS             complement(18356..19339)
                     /locus_tag="UXQ66_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="XAH93209.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            19765..20508
                     /locus_tag="UXQ66_14985"
     CDS             19765..20508
                     /locus_tag="UXQ66_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="XAH93210.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(20824..21384)
                     /locus_tag="UXQ66_14990"
     CDS             complement(20824..21384)
                     /locus_tag="UXQ66_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH93211.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(21589..23133)
                     /gene="qac"
                     /locus_tag="UXQ66_14995"
     CDS             complement(21589..23133)
                     /gene="qac"
                     /locus_tag="UXQ66_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="XAH93212.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIVSSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFVIIAIVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMTSVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGTASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            23310..23876
                     /gene="qacR"
                     /locus_tag="UXQ66_15000"
     ARG             23311..23873
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            complement(24086..24694)
                     /locus_tag="UXQ66_15005"
     CDS             complement(24086..24694)
                     /locus_tag="UXQ66_15005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAH93214.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRDYDEIIETVSYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGSS"
                     /name="recombinase family protein"
     gene            25061..25291
                     /locus_tag="UXQ66_15010"
     CDS             25061..25291
                     /locus_tag="UXQ66_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002471858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAH93215.1"
                     /translation="MDSIENACLISQITFKVNSPYKNMSEDYMDIKESDRIIMKAILNK
                     CGIDLQKSNHKLNNVMPSYNVFIRKDELDYR"
                     /name="hypothetical protein"
     gene            complement(25441..25536)
                     /locus_tag="UXQ66_15015"
     CDS             complement(25441..25536)
                     /locus_tag="UXQ66_15015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAH93216.1"
                     /translation="MLEILVHITTTVISGCIIALFTHWLRNRNNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            25701..26375
                     /locus_tag="UXQ66_15020"
     CDS             25701..26375
                     /locus_tag="UXQ66_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="XAH93217.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEIRDML
                     AS"
                     /name="IS6 family transposase"
     ARG             complement(21593..23133)
                     /name="qacB"
                     /gene="qacB"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacB"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.42"
                     /coverage="100.0"
     ARG             10795..11639
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     Typing          complement(17844..17991)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(18050..18225)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(18357..19339)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19766..20508
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gggaacaacg acatgataaa atggtagtta gctatatttt tctaactttg caacagaacc
       61 agaatattca tttaactcct cctatatagt gttttgcaat atttacgttt tatagattat
      121 tccaccattc aaagttatct tgtttaagta attgatcgct ttctttaggt ccaaaacttc
      181 ctggtttata ctgtggtatt gttacgttag attttttcca ttcagtactt atataatcta
      241 taaattccca tgattgttta agttcttccc aatgtacaaa attagtttga tttcctatta
      301 aagcatcaca tataagtgat tcataagcat ccactacttg gtttttatct attgagttat
      361 aaattttcat attatgactt ctattatttc tatttgattt attttcataa atatatagtg
      421 atattttggc attaggttct atatttatta ccagtaaatt acaatcagta tcctcattat
      481 tattttcata tcttaatgta ttattgtttt ttttgaattc tataacaatc tctgttgctt
      541 ttttacctaa gcgtttcccc gtacgaatat aaaatggagt cccttcccat cttctattat
      601 tgataagtac ttttcctgct acaaatgttt ctgttgttga atcactatca acaccttttt
      661 cttcatgata tgacattatc ggagtttcat taataatacc attaatatat tgtcctctaa
      721 caaaatattt gtgtacatca gcccctttca aaaattttat attgtttaaa agttcgattt
      781 tttttagtct aatatcttta ctatttctgc tttcgggttt ctccatagca ataagagtaa
      841 gtatttgtag tgcatgattt tgcaccatat ctttaagcgc tcctgtagaa tcatagtatt
      901 ggcctctatc ttcaatgcct aaagtttccg atagagttat ttgaacattt gatatatact
      961 tgttgttcca caatggttca aatattgtat taccaaaacg taaagattca atattttgca
     1021 ccatctcttt acctagataa tgatctattc taaatatttc ttcttcttta aaatactgtc
     1081 ttatgtgttt atttaagtct tcagcagatt tcaaatcttt tccaaatggt ttttcgatta
     1141 ttaatcttga aaatccattt gtatcagaaa gacctgattg gcttatgctt tgagttataa
     1201 ttttaaaaaa ttgaggattc attgctaagt aaaataatct attgccatcc aaacaatatt
     1261 ttttatcaat atcattggaa agttccttta atttattcca acttgtttta tcttcaacat
     1321 tttgttgaaa gtaaaatatg ttatctaaaa ataagttcac catttcaaaa ttttctcggc
     1381 ttaataaaat ttgttttact ttacttctat attcttcatc acttatatcc tctaaacccg
     1441 tagaaatgat aactaatttc ttaaagtgac cctttttata aagattaaaa atagaaggta
     1501 gcaatttcct gtaacttaaa tctcctgttc cgccaaatat tgttattaat gatgataaat
     1561 ttttatccaa agcagttccc cccttttact tgattagcta gtttctggtt ttcattccgt
     1621 aacagtaatt atattactct tcatcccatt gtgtgtggaa cacaccttca tgatctttac
     1681 gttcataagt atgtgcacca aaatagtcac gttgtgcttg gataagatta gcaggtaaat
     1741 cttcagaacg ataactatca tagtagttca cacttgcaga gaatcctggt gttggtacac
     1801 cgtttttaac gcctgttgct acgacgtctc ttaatgcatc ttggtaatct gtaacaatat
     1861 ttttgaagta tggatctaat aataagtttt caagttctgg attattatcg taagcatctt
     1921 taattttttg taagaattgt gcacgaatga tacaaccttc acgccaaatc attgccagtt
     1981 cacctaattt taagttccat tcgtgatctt cgctcgattt tctcatttgc gcaaagcctt
     2041 gagcgtaaga acaaatctta ctcatatata atgcttttct gattttttct aagaattctt
     2101 ctttattacc atcaaatgaa gcttgtggtc catttaatga tttagacgca ttaacacgtt
     2161 cttctttaat ggatgaaatg aaacgagcaa ataccgattc agtgataatt gttaatggaa
     2221 ttcctaattc taatgcatta atagaagtcc atttacctgt acctttttga ccagcagtat
     2281 ctaatatttt ttctactaat ggttcattat tttcatctaa tttagtgaaa atatcaccag
     2341 taatttctat taagtaactt tcgagttctc cagcattcca atctttgaat gtttgagaaa
     2401 tttcagtatg actcatacct aataagtctt tcatcattgt ataactttca gcgattaatt
     2461 gcatatctgc atattcaata ccgttatgaa ccattttcac ataatgacct gcaccatttg
     2521 ggccaatgta tgttacgcaa gatgcaccat cttgcgcttt agctgcaatg gcatctaaga
     2581 tatcactgac tttattataa gcggcttctt gaccaccagg cattaatgaa ggaccagtta
     2641 aagcgcctac ttcaccacct gatacgccca taccaatgaa attaacgcca ctttcagcta
     2701 atgttttatt tcgacgaatt gtatcttgat agtttgtatt accaccatca attaaaatat
     2761 cttcatcgtc taataatgga agtaaggcat ttatcatgtt atccgtagga ctaccagcct
     2821 taatcatcaa caaaatttta cggggttttt ctaatgaatc tacaaattct ttcaagttat
     2881 acgcaggata tatcttttga taatgagact tttgaatagt atcattaatt tcattattat
     2941 ctctactatg aatactcaca gaatatttct tatcctcgat gttccacgca agatttttcc
     3001 ccataacacc taaacctaaa attccaatat tactagacat tgtatcctct catttcttta
     3061 tagtttataa cctacaatct tgcttcaaga tcttttttca tatcttcaaa tcctggttta
     3121 ccaagtaaag caaacatatt ttgtttatac gcttctacac caggttgatt gaatggattt
     3181 acgcctaatt gataaccact catagcacat gcaagttcga agaagtacac gacatagcca
     3241 aatgtttctt catctaattg tggaatatta acaacgatat taggtacgcc accatctgta
     3301 tgtgctaata atgtaccttc aaatgctttt gtattaactt catcaattgt tttaccagca
     3361 agataattta atccatctaa atcgtcacta tcttcttcaa tagtaagatc atgttttgga
     3421 tgattcactt ttacaactgt ttcaaataag aaacgacgac cttcttgaac gtattgtcct
     3481 aatgaatgta aatcagtagt gtagttagca cttgaaggat aaataccttt aaagtcttta
     3541 ccttctgatt caccaaataa ttgtttccac cattcgttga aatattgcat tgacggttca
     3601 tagttgataa gcatttcagt tgtataacct ttgctatata gaaggttacg gattgttgca
     3661 tattgataag caatattttc ttctaatttg tcagaagata attctttacg tgcttttgct
     3721 gcaccaatca tcatcgcttc aatattaata cctgcagctg cgattggtaa taaacctaca
     3781 gcagttaaca ctgaataacg gccacctaca tcatcaggga ctacaaatgt ttcataacct
     3841 tcatttgtag ctaattgttt taatgcacct ttttgtttat ctgttgtagc aaagatacgt
     3901 tttttagctt cttctttgcc atatttactc tcaactaatt gtttgaataa acggaatgca
     3961 actgctggtt ctgtagttgt accagattta gaaatgacgt ttacagagaa atctttgtca
     4021 gctaaataat ctactaattc ttttgtatag cttgatgata aatggttacc tacaaaaaca
     4081 atttcaggat agtcattatt tgttctaaat gaagatgtta gcatttcaat agcagcacgt
     4141 gcaccaaggt atgagccacc aataccaata acaactaaca cgtcagaatt tgctttaata
     4201 cgtttagaag cttctacaat tcttgaaaac tcttctttat cataatcaac tggaaggtct
     4261 acccaaccca agaaatcatt tcctgcacca gttcctccat gtatcgtttt gtgtaatgtc
     4321 ttcacgatat ctttttgttg ttctaattca tgttctccaa aaaattctaa agtcttacca
     4381 taatctaatt gaatatgagt catctaaaaa gcctccaaat ttgtaattat tagtcttata
     4441 tttacaattc caactgtaca ctacagtgta atattattca tactgaaaaa atagtcaccc
     4501 cctttagata agctgacatt ccctatatgc caattttgtc agtattgatt tattgataat
     4561 tatgtcaaaa taaaggtata aattaatgaa aggatgaatt atcgtggaat tacaattagc
     4621 tattgattta ttaaataaag aagaagcagc agaattagcg aaaaaagtag aagaatatgt
     4681 tgatattgta gaaattggta caccaattgt gattaacgaa ggtttacctg ccgttcaaca
     4741 tttaaatgaa aatataagca atgctaaagt attagcagac ttaaaaatca tggatgcagc
     4801 agactatgaa gtaagccaag ctgttaaatt cggcgctgat gttgtaacaa ttttaggtgt
     4861 agcagaagat gcgtcaatta aagcagcagt tgaagaagca cataaaaata acaaacaatt
     4921 attagtagat atgattgctg ttcaagattt agaaaaacgt gcgaaagaat tagatgaaat
     4981 gggtgctgac tatattgcag tgcacactgg ttatgattta caagctgaag gacaatctcc
     5041 attagatagc ttacgtaaag ttaaatcagt aattaaaaat tctaaagtcg cagttgctgg
     5101 tggtattaaa ccagatacaa ttaaagaaat tgttgcagaa gaacctgact tagtaattgt
     5161 tggtggcggt atcgcaaatg ctgatgaccc tgtagaagca gctaaacaat gtcgtgacgc
     5221 tattgaaggt aaatagtgat gacaactttt aatcattatc aattaatttt agatgagcta
     5281 aagggcactt tatctcatgt taaagatgaa gaatttgatg gatttgcatc agaagtaact
     5341 gaagcatcac gtatatttgt tgcaggtaag gggcgttctg gatttgttgc aaatagtttt
     5401 gcaatgagac tcaatcaatt aggaaagcaa gcatttgtca ttggcgaatc aacaacacca
     5461 tcaattcaaa aagatgattt atttattgtg atttctggtt caggttcaac agaacatctt
     5521 cgcttattag cagaaaaagc gaaatcagtt gatgcaaaag tggtattact aacaactaaa
     5581 ctagattctg caattggtga aattgcagac acagtagttg aattaccagc aggtacaaaa
     5641 cacgatgcta ctgggtctga tcaaccgtta ggtagtttgt ttgaacaatc atcacaaatc
     5701 tttttagata gtgtagtcat tggactaatg acacaattag atgttgatga aacaactatg
     5761 caaaataatc atgccaattt agaatagata taaataagca gttaatgcgg aagattatat
     5821 aatcttccgc attaacaatg taaattctaa tattatagaa gaaagaagga tgaaaattgt
     5881 attataaagg aaaagaattt ttcacttcta aagatttagc tttatgtgtt atcggaggaa
     5941 agtggaagat ccctataatt tttcatttac ttcaagacaa agtattgaga ttaagtgagc
     6001 tacaaaaaaa gttgccgcat gtcaatcaaa ggatgctaat aagacaactt agagaattag
     6061 aagaggacca aattattgaa agacatattt attctgtagt tcccccaaaa gtggagtata
     6121 agctgacatc tataggctac aagctagata aggtggttta tgcaatatgc gaatggggtg
     6181 atttattcaa ggatgaaata atacattaaa aagttctggt gcaaattaaa aataaagtta
     6241 actactctct tataatgtaa gtattcaatt agctgactaa catgtattaa tttcgccgtt
     6301 ctatgaaatt aagggttctg ttgcaaagtt agaaagatat atctaatcac cattttattg
     6361 tgtcagtctt cacctaacca gctaacatat aactaatttc gtggcatggt gaaaatccgt
     6421 agatctgaag agacctacgg ctctttttat ataatccgta aatacattca atgcctttga
     6481 gtgtattttt tgccgtattg acactttgat atcttgtctt tcttacttta atatgacggt
     6541 gatcttgctc aatgaggtta ttcagatatt tcgatgtaca atgacagtca ggtttaagtt
     6601 taaaagcttt aattacttta gctattgcta ctttcgttga aggtgcctga tctgtaatta
     6661 ccttttgagg tttaccaaat tgtttaatga gacgtttgat aaacgcatat gctgaatgat
     6721 tatctcgttg cttacgcaac caaatatcta atgtatgtcc ctctgcatca atggcacgat
     6781 ataaatagct ccattttcct tttattttga tgtacgtctc atcaatacgc catttgtaat
     6841 aagctttttt atgctttttc ttccaaattt gatataaaat tggggcatat tcttgaaccc
     6901 aacggtagac cgttgaatga tgaacgttta caccacgttc ccttaatatt tcagatatat
     6961 cacgataact caatgcatat cttagatagt agccaacagc tacagtgata acatccttgt
     7021 taaattgttt atatctgaaa tagttcatac agaagactcc tttttgttaa aattatacta
     7081 taaattcaac tttgcaacag aacctcattt actatatggg catctctttc attattaata
     7141 caaagctttg tatctccgat attaggcaaa ggtgtaaacg aattaggtga tactatagga
     7201 ttcaacatta tattaatcgt ttctttaata atgattatct tcttattttt tataaatcgt
     7261 agtaaaaata tctcctatga ttatataaaa gttcaaagag gtgaagccaa tgaataaatt
     7321 agaaaaatgg tctttggtat ttattatttt tacatttctc tcttcattag cacttttata
     7381 tttcaaatat aattttagtt cggttatgcc agtcctaagt ctttctattt taactatact
     7441 aatattgttg acgagtatta ttactgtagt ttcagttaat gatgaagata cttaaaacgt
     7501 tcattagtga aacaggtatt atattaaaaa agcgtacgaa tttgtacgct tttttcttgt
     7561 gttattatta aaatctcata acaggaaaat attatgagat tttagacgct gtcagaacgt
     7621 ctcttttaca tcgagtgaca ttgaatcaaa gtctttgtat gttaatgata tataaaatta
     7681 tttagtagat tcattatagt aagctagatt agttgctcta cttgttttta ttctcttttg
     7741 cctctaattt attgagataa cgataaatag ttgtacgtga aacttgccac tgctctgcaa
     7801 ttgttttaat tggcgtacca ttatcataaa gtgtcttaag taagtttaaa tcttgtttat
     7861 ttaatttttc aggtctacct ccatatcggc ctctagcacg tgctgcaatt cgaccggctg
     7921 atgatcgctc taaaattaaa ttacgttcaa actctgcaaa tgctgcgaat aaatgaaata
     7981 ataattgtcc tgtagaactt gatttatcca tcgttatatt ttcttctaaa ctatgaaaac
     8041 tcacacctcg ttcgttaagt tcattaacta acgtgattaa atcctccatg ttccgtccta
     8101 gtctatctaa tctccaaaca acaatcgtat ctcctgacct cgcaaattca attgctttat
     8161 ctaaaccagg tcgcttactt tttgaaccac tcatatggtc attaaatatc ttttcacaac
     8221 catatgtatt taatcgatcc tcctgtaaat tcaaattttg taatccagtt gaaactcttg
     8281 cataacctat tttcaaaata cagacctcct atatacacct ttagtgtacc ataacttgat
     8341 tacgaggtct tttgtgaaca tagatttttt gttgggtttt tgaacacata attctatgta
     8401 atacatactt atttagacat aaaaagagag tgtacagaaa atggttattt tatgtacact
     8461 ctcatcttta ctaatatatt ttaaatgtta ttaacaaaac taatttaata agagtcaagt
     8521 atagtttaca tatgtataat gtttgaaaca tatctctaat tactttttac taatatcatt
     8581 taaaatgtct cgcaattctt caatttcttt gttatttaat tcttcatttt tcgcaaaatt
     8641 tagcactaaa cttttcatgt cccctccata cagtttatta agaaaagttt tagcagtttt
     8701 cattttaata tcgtcttctt taatatttga tgagtaaaaa taaatattct ctgatttgta
     8761 tcgttttata atctcttttt tatatagtct tgtgattaat gttctaattg ttttatcgct
     8821 aacttcttta tatttttgaa tttcaactac aatttcatta gctgatactg attttttatc
     8881 ccatattata ttcataacat cccattcagc catagatatt tcaacttgct tattggccat
     8941 ttaaaacacc catttctttt aatatttttt cactgattaa ttcagcattt ttcccagacg
     9001 ggtttccatc tgataaatgt gtagcaaaat aatacttatc atgatttgta attacgtaac
     9061 ctacaaacca cccattatta tacttcccgt ttactatacc tgtacctgtt ttcccataca
     9121 gttcatactt ttcatttttc ttaatcaata atgaagaaga taattgattc tttgcttttt
     9181 tactaaaatg gttattttgt tccatcatat ttttaaaaac tattacttgt tcaagattag
     9241 atattttcaa actatcttcc atccaatagt ttttataact tcccaaattt tcattaccat
     9301 aatttaattg cttgagttga gccgcagtat agttctttgg tatttgatta ctaatacgtt
     9361 cgaagtacca attaactgaa ttttgcattg ctgtatttaa atcttgttcc ttattccaag
     9421 actcgaaagg ataatgttta tgattccatg acatacgtga atttttatca cttatgatat
     9481 gacggtcaag tccaaacatc gctaaataaa ttttataagt tgaatcagga gaatatcttt
     9541 ttctactttc tttttcatta taaatatagt atttgtcttt cttcatgctg tacatgacga
     9601 aagatccact atttgaacca aaatttttac tttcatctaa aatttggtga tcgttctgta
     9661 agggcttttt ataattataa tcagttatgg attgccccat caaaaactgg ctttgaatta
     9721 ctatgagcaa aaaagtaaaa atacaaataa aaattggaat taatttagac tgttttttca
     9781 aattggcttc ttttatatta attaatcttc ttttgagtaa tgacttttta ccattaaatg
     9841 aatggcttaa tatattttta ttaaaaaatg gaatatttaa tacggagtcc ataatagatt
     9901 ccgcataagt tttaaattca tttttgttaa tattattaag aacaaatcta tcagcttcta
     9961 cttcattgtc atgaattatc tttcttttta caatatgtat taatggattg taactcataa
    10021 caatagagaa gatattaaag ataattaaat gtaaagtatc tctattttta gcatgagcat
    10081 attcatgcag tattatatat tttagtcttt tatcaattac acttttaaaa tatgaactag
    10141 gaatcaaaat aatatatttc ccataccaaa aagttattgg agattgaata gcctctgctt
    10201 ttcgaatcac aatatttttt ttatattgat ggttgaaaag tatcgtatct attttatttt
    10261 tttcattttc gtttagataa agtgactgtt tctttaaata tttaagatat aataaggctt
    10321 tcaaaaattt aaaacttaaa ataataacta aaactatcca aataactgtg cagatattat
    10381 caattgaatc ccaattaaac ttatggatat ctgttgtgaa ctcttgaata ggtttggtgg
    10441 tatttatgtt atggttcaaa tcgtgtgact tactttcaac tgtgggcgct tgattattca
    10501 cattattaaa ttttataaaa gagaatttaa ttgggataaa aggaattaat ccagcaagca
    10561 tagttagata ccaaacttta taatttaaac tataattaaa atagcgtttt aatatgtacc
    10621 taaaaaatac taacaataga aatataaaac aaaagcttac tacgctcatt attagtaatt
    10681 tagccatttt gacaccttct ttcaaatatt tataataaac aattgacatc aatattacaa
    10741 ttgtaatatt attgatttat aaaaattaca actgtaatat cggagggttt attttgaaaa
    10801 agttaatatt tttaattgta attgctttag ttttaagtgc atgtaattca aacagttcac
    10861 atgccaaaga gttaaatgat ttagaaaaaa aatataatgc tcatattggt gtttatgctt
    10921 tagatactaa aagtggtaag gaagtaaaat ttaattcaga taagagattt gcctatgctt
    10981 cgacttcaaa agcgataaat agtgctattt tgttagaaca agtaccttat aataagttaa
    11041 ataaaaaaat acatattaac aaagatgata tagttgctta ttctcctatt ttagaaaaat
    11101 atgtaggaaa agatatcact ttaaaagaac ttattgaggc ttcaatggca tatagtgata
    11161 atacagcaaa caataaaatt ataaaagaga tcggtgggat caaaaaagtt aaacaacgtc
    11221 taaaaggact aggagataaa gtaacaaatc cagttagata tgagatagaa ttaaattatt
    11281 attcaccaaa gagcaaaaaa gatacttcaa cacctgctgc tttcggtaag actttaaata
    11341 aacttatcgc aaatggaaaa ttaagcaaag aaaacaaaaa attcttactt gatttaatgt
    11401 taaataataa aagcggagat actttaatta aagacggtgt ttcaaaagac tgtaaggttg
    11461 ctgataaaag tggtcaagca ataacatatg cttctagaaa tgatgttgct tttgtttatc
    11521 ctaagggcca atctgaacct attgttttag tcatttttac gaataaagac aataaaagtg
    11581 ataagccaaa tgataagttg ataagtgaaa ccgccaagag tgtaatgaag gaattttaat
    11641 attctaaatg cataataaat actgatatca tcttatagtt tgtattatcg ttgacatgta
    11701 taattttgat atcaaaaact gattttccct ctattatttt cgatatttat tttcttaatt
    11761 ctctttaaca aactagaaat attgtatata caaaaaatca taaataatag atgaatagtt
    11821 taattatagg tattcatcaa tcgaaaaagc aacgtatctt atttaaagtg cgttgctttt
    11881 ttctcattta taaggttaaa taattctcat atatcaagca aagtgacaat agcattttac
    11941 aagtattttt tattgttcga ttagggtaaa cctaaataat acataaatta tattacaata
    12001 tgtttattat agaggctaaa gtatcttaga aatttggata gtaggttttt cgggaataaa
    12061 agtatagttg gctttaatat ataattaagc taagctatca tttatattta ctcgattata
    12121 attcgcactt caactttttt ataacgtaaa aattaaaacg tagttttatt tatctttagt
    12181 aatatctttt taaacactac agtttcttca ttagttaaat tagcgaagta atgattatta
    12241 agttgatagg ctttcttttc taatgttggc cataagtctt ttgctttatt tgtactgttt
    12301 attagcacag ttcttctatt ttcattatca gtttgacgtg ttattagatc ctttttggac
    12361 atcttatcta atattccaga tattgttgaa ggttctaaat ttaaagtatt accaatcgct
    12421 ttaggtgtat tcaaattact attaatcaag caattcaaaa caccatattc tgctggagta
    12481 atattatagg gacttaataa acttttaaaa tgtttaaaaa ctctattctg agaagtactc
    12541 aacaaataat ttatacaatt atctaattcc acaactaaaa cctctcttaa atcattagta
    12601 ttgactcgct tatcatatca tgataagttt tgtaggaaaa tagttttgca acaaaaacat
    12661 acttctacaa aacaattgtg aaagaaggct aataaatgtt caatgcggta gtagtgagaa
    12721 aaagtgcatc aaatgttagt tataaagtag aaaaagttga tgaatctcat ttatcgaagg
    12781 gtgatgtatt agtaaaagtg gtatactctt caataaatta taaggatatg ctagctttac
    12841 aatataaagg cggtgtaatt agagattatc ctatgattcc tggtatagat tttgcaggta
    12901 ttgttgaatc aagttcgaat gataagttta aagaaggcga taatgtatta gttactggtt
    12961 atgatgttgg cgtgacacat acaggtggat tttcagaata tgcacaagtg cctggagagt
    13021 ggattgttcc tattccccaa gaaatgtcta ttaaagagtc tatggtatat ggcacagccg
    13081 gttttacggc agcattatca atttttgaac tagaaaaata tggaatgaat atcaaatcac
    13141 aacctgaaat tttagtgtct ggggctacag gtggtgtggg cagtgttgct atacaaattt
    13201 tacataaaat tggatatgaa aatatcactg ctatcgtaag aaaagaaaag caaatagaaa
    13261 tcgcaaaaaa attaggtgca aaacaagtaa taataattga agatgataat aaaccgctta
    13321 aaaaaggtat ttttgattat ttcttagata cagtggggag taatgtaaca ttatacggtt
    13381 taaaacgtct aaattatcaa ggtgttgcta ctgtatgtgg aaatgtagca ggaaattcac
    13441 ttaacgctaa tatattaccg tttattctta gaggtattaa attaattggc attgattctg
    13501 tatatgttga tcataatatc cgtgaagata tatggagtaa gttagcaaat gaatggaata
    13561 taggaaattc acttctatac aatgaaattg gatttgaaga attctataaa acgatagatc
    13621 agcttttaaa aggacaacat ttaggaagaa ctattttaaa agtataagtg tgagtattca
    13681 ttaatacatt tactattaat tcaatcattt tgcatttctc tactaaccag tgttataatt
    13741 tatataacga aaatgattaa caattaatgc accaatcccc acactattgc agtagtgtgg
    13801 ggattttttc gatgctggct tataaagtcg cctattaatt atttgttgcg tttactaagc
    13861 caataagtat aatacgcaac agcacagcca ctgatgactg gtgctatgat gtgaacgaaa
    13921 atgattagca aagtaatgca cctcctctct tcgtcaattg acgcctgaga gataggcgac
    13981 tctattatta taccatctgt gaatatacaa gcatatctac ttccgataag tcgtcttatg
    14041 ttatataact ttgtttttta tagtatcaag acaagaagaa actcgtttca aaaaccctca
    14101 tgatttttag agaaaaactc tcttatttca tcgtctttaa taaaataata tgccatcttt
    14161 ccatctttat aaaaatcaag tacctcattt ttatataaaa gccttaaatg atgtgaagtt
    14221 gaagcaacac tcattttcaa tatcaaagaa atatcacaaa cacacaactc atcttcttta
    14281 atcaaagata atatgatttt caatttcttc tcatcacaaa ttttttctaa aatgttaagt
    14341 aatttcttag atttatcatc ttctaaaaaa cttaaagcat tgttaacttt atcctcatgt
    14401 acacagatca catcacaagt attttcataa ctcatataaa atcacaccct aaattaaaat
    14461 ataaatccta aaattgtttg aatagtgtca ttttcaataa taataaataa acctaaagct
    14521 atataaataa tagccataat ccaacgacta aatttctcaa caatttctcc aattcctgga
    14581 atattagcta atttttgtgc agtaaacacc aagaagaaaa ttaaaattaa aaagacaaac
    14641 agagtaagta ataaattagt aacacttaat gtcacaaaat acggaacaaa taaaccaata
    14701 ttatcggcgc cacaacttgc tatcgtaaca attgcaaccg taccaactaa tttagacaat
    14761 cctttttcat tcaattcttt tttagctctc ttttctcctt cacaatcatc ataaatagcc
    14821 actttaattc caagataaat tggtattaaa cccaataaac ctaatatcca cttttctgga
    14881 acataattta atacaaaagc taaaaacaaa ctaactaata ttaaaataat agaccctaaa
    14941 tattgaccaa cataaatatc tctatattct tttctagtct ttgctctagc aaaaaatatt
    15001 aataaaatta ctaataaatc aactgctgta gcaatataaa gaacagcagc agcaacaacc
    15061 gtttgaatca taatacacct cattcaaaaa tatttttgaa tgtattataa cttatatttt
    15121 taaataatca taggtgcttt attccaattg ctttattgac gttgagcctc ggaaccctta
    15181 acaatcccaa aacttgtcga atggtcggct taatagctca cgctatgccg acattcgtct
    15241 gcaagtttag ttaagggttc ttctcaacat caataaattt tttcggcata aatgcgtgtc
    15301 tatgcgtaga catggagaca cttcagaatt atggagtgat tacatgagtt taactatttt
    15361 tctttattca gttttaggaa gtttattagc aaattatatc tacgaaaaat cttcaaaata
    15421 aataactttt tcggttctat tttgtacact ttatctacct ggtagaccta attgttattg
    15481 ctttacaggt ctaaaattcg tcgttataat ctagttaaat cccgtaaggg cgcacttata
    15541 cgtcggataa atcgacatgt gcaaaaacgt aatcgacctt cgtcgatttt tttatttcaa
    15601 aattaaagaa acggcttgag atattccgag cagttataaa aattaatttg cgttgaatat
    15661 tgctactaca ttcttgaaaa agtgatgtag atttatagcc cataactttt ttgaattaca
    15721 tcgacgatac ggcgtcgaaa gaaaaataaa tagaccgtat gaaagaaaaa gctacctcac
    15781 tttatctggg gtagctttta ttttttatgc ccttattttg aattttaaga gggcatttta
    15841 aagatttagg ggtgattcat atagttttat atctaaaact tatatatgct tttaaaacgc
    15901 aaatatgagc caaataaata tatgctattt tcaaaaacaa aaatttgagc aaaaacaata
    15961 actattttta gacactgccc atttacatgc aaattaaaaa ttagcataaa attctttaaa
    16021 acttccccac gtttttctaa attcctgtag ggcgttttta tcaaaaatca agacaagaag
    16081 aaactcgttc acactcgttt caaaaaaaca agaaatctaa tctatacacc taccgttttc
    16141 caaccccctc aaagcataca aattaaaaac aaaattattc ataatcttac tttcttttaa
    16201 caaaaacata aaaaccataa atagacaaat taactatcaa aggcaataaa cagtataaaa
    16261 aaaccacgaa taaatcttca tcaacatcta aaataaaaaa gaataaaaca attaacaaaa
    16321 tactaattaa caaacctaaa agtggcaaac tttttatata tttttctaaa ttttcattca
    16381 taaaatagac tcctttcaaa aatatgttta taaatatatt aaaataaata ttgattttat
    16441 aaagcgctta cttatacaat taaaatatct tattatcttg gaggtatcaa atgaaaatta
    16501 taaaattatt ttcaataatt tccttgttcc tactggtatt tagcgcgaat ttttctaatg
    16561 cttacgcaaa tgaagaacaa aaaagttctt tactagaaaa tcaaaaagaa aaattgaaaa
    16621 gcaaaaacat cgaagtatca caaatgacca agaaagaaat aagttttcta gaacaattgc
    16681 aaaataaaaa tgaagatatg caaaaattcg aaaagcaaat gaaaaaagaa ggatttaaaa
    16741 aaataaagct agaagacaaa aattctaaat taaaatatct agctacagaa gcaaatgata
    16801 aaaatgcata tggctacata gctaataacg cttataaaaa tgaaaaaaca aaagaaattg
    16861 tagtttctga aacaatatat gataactaca acaaaaaaat cacaaaattc attgccgaaa
    16921 aaagaagtat gactgaaaac aaagagggaa aaatacttat taacaaaaat tacgttgaat
    16981 ataaggctga aaaagttgat aaaaacagac cggtaacata tgcaggattc aaatggaacg
    17041 gcaaagcatt cgcttgtagt atggctggac tttatgcatg tgctcactac tgtggagtat
    17101 gggcaatcgt aaatccaata gccggcggtg tatgtgaagc agtttgcgga actgcatttg
    17161 cagctggatg ctctgtaggt tgattttatt ccaattgttt tattgacgtt gagcctcgga
    17221 acccttaaca atcccaaaac ttgtcgaatg gtcggcttaa tagctcacgc tatgccgaca
    17281 ttcgtctgca agtttagtta agggttcttc tcaacatcaa taaatttttt cggcataaat
    17341 acgatgttcc ttatttatcc tcataaaaaa caatagctga aatatataac caattactgt
    17401 gtgtttgaat ttctaataca tgaatatcat tctttaaaaa cctattaact tgtttatcta
    17461 attgacgatg agtaaaagta gcgaaagttt taatcttcat gatatctctc cttttataaa
    17521 aatagcaatc cttattacaa tattaaacac ttttattttg gattttaaga ggcattttga
    17581 agacttagag gcaaatcata taggttttgt acttaaaaat ctatacagtc tcttaaaacg
    17641 caaatatgag ccaaataaat atatgctaat ttcacaaaca aaaatttcag caaaatcagt
    17701 gactaatttt ttagatactg cccatttaca tgcaaattta aaaattagca taaaatactt
    17761 taaaacttcc ccatgttttt ctaaattcct gcagggcttt tcttatcaaa aacttagaaa
    17821 ttttaattta actctaaaat ctccgtaaga gcataaggga aatttgctat cattcaaaaa
    17881 tgatagatct ggcaaggcca gacattccaa gggttttaag ttattttaaa gtgatatcat
    17941 acaaagctgt agtgtcacac ttttgtgaca ctacatacag catttgtcac aaaaataaga
    18001 cagcactttt ttacagaaaa acaataaaaa aagacatcag ttatcactaa tgtcttaaat
    18061 aataattttg cttttcgaaa ttccaaattg cggtaattga atgtgctttt tttcttcgtc
    18121 tgtcgtttta tcttcatcac ttgtattaat caaattacca tcttcggcat cgtctaagtt
    18181 taaaatttta tgcttttgtt taagcaatcc accataactt aacatacgtt ttcgatacaa
    18241 acctttttct aaatcactta caatttcttg atttttttcg tcgtcatcag ttaaaaagtc
    18301 agatgattta acggaatatt ttgatgtctc ttcgagtgtt ataaaatcat ttgaattatt
    18361 gattaaagat attatattgt ttcatgtttt tacggcgcat ataaagggca tgtgtttctt
    18421 caagttcagt tagaattgtt tgcattaaat aagcttgcat tgacttgatt gtttcctttt
    18481 ggcctttaac tcccctatca tgtatagctt ttttaagtct ttttaaagaa gttaatattt
    18541 catcctcaat gtcctctaac atgtaatgca tatcttcatg ccttgaatta aatgattttt
    18601 ttgctttaag aataacagcc tttatgattt ctaaatctct ataatcatat tttaataaat
    18661 aattagttag ttgttctggg aattcttgca atagcatttc tttatcatca aaattatgtg
    18721 taaattgatt tgaatgattt gaatgattac taatttcatt tttgtacttt atatcattca
    18781 agtcattcat atcattattc tcagtatcat taaagtcaat gtcattaaag tcagtatcat
    18841 tagtgttcga ttttcgaact tctggacgtt cgattttcga acttctggac gttcgatttt
    18901 cgaacttctg gacgttcgat tttcgaactt ccttctcgcc gtaaggttca acatcgtttt
    18961 cttctttttc tattttgtaa atatcacgtt ctgtgacaat aggtttcatt aaatatagaa
    19021 tatttggttt atttaaacca cgtcgttttt gaatgagtag accatcgttt tctaaccctt
    19081 tttttatttt tgttaacttt tcttttttac aatttaagat ttccattagc ttttcatttg
    19141 aataaacaaa gtaaatgtta ccatcttcat caacccagct atttttaata gataaattta
    19201 agcgatcacg taagatagca taggctattt tcatatcatt agttagattt ttataatttt
    19261 cactggtaaa gaatacttta gggatttgat aaaatctttc tttgtaattt tcttgcactg
    19321 taaaatattg attttgcatg acaaaaaacc tctttccata ttttagtttg gtaagaggta
    19381 ataaaacgtt tttatttagc tttacattta tttaatgatt taggtgcttg cactaagata
    19441 ttattcatta tataatacaa gtatcgaaaa ttatataaat aaacagtttc taaacgtttt
    19501 attaccaaac cccgactatt accagtagtt ggggtttttg ttatattaag tttattatag
    19561 cactttaaat aaacttataa aagggaaaat atagctttat caagggttta taaacccttg
    19621 ataaatatca taaacctttc ataaaccctt gataaaaagg ttgatggatg tttattttta
    19681 tttattaatc actttattat taagcattat aagcttataa tattttatca agggtttata
    19741 aacattttat aaagggttga tgatatgaaa agtgtgaaaa agttgagtga agaattaggg
    19801 gttagtaagc aaacgatttt taataatatt aagcgattga atatagagac aataaaacag
    19861 gaaaacactt cgtttattaa agaagatacc gatatagaaa aaatcattca aagagtaaat
    19921 gaaaataaaa agaaatatgg ttttgaaagt actactgaag acaaacaaaa aaaagggtcg
    19981 gataatatta attttgaatc gaaaagcgat gctcaaatag tagaaatcct taaaaatcag
    20041 attgatactt taaataatca aattgaaaaa caagaaagtc gtcatgaaac aacaattgaa
    20101 ttttacagaa aagagttgca agaaagatca aaattgcttg aaaatcagca agttctggca
    20161 ttagagagta ataaaaagat tcaaaaatta gaaaatcaat tagaaaaaga aaaacacctt
    20221 aattatccct ttgatacatc tactaacact agacaaaacg ttgatgcaca agaaaaaaca
    20281 tatactacta atcctgtaaa tattaacaga gatcaggaag aaactaaaga aacagagatt
    20341 caatataagg atatatctgg aagtcaaagc gacgaaagta cacaaggtga agaagcaaaa
    20401 aaagaagacg ttccagctaa tctaaatgac aatgatagtg atatagaaga aaagagtgaa
    20461 gaaacggaac ctaaaaaggg gttttggagt cgtttgtttg gtagctaaaa taattgatta
    20521 ggcactaaaa gttataaaat tttagtgtct tttatatagt gagaacttct ggtaatcatc
    20581 agttatgtta aactctaaca aaaactaaat tatcagaaga attatctagg gtattaaaca
    20641 taggtaaatc aattttctat cgccaatagt ataaacatca tccatattaa tctgaagata
    20701 gctacataat tctttaacag catagccttt atttgtataa ggcgccataa actctattaa
    20761 atatggtttg ttttgaggtt tctatgttta atcatttaat ttttcattat ataaatcgaa
    20821 taattataaa aagtcatcat actttttatt ttttaaaaat atttgaaaat ttaatagtaa
    20881 tccaattata agatcaaata tcattatcat tataatcaag gcaactataa tcactgtgac
    20941 actcgttaca taacaagcta gtaatctcca gataaaattg acattttcac caattccata
    21001 acttaacata ttacaaagta gtaaaagaat aataatacct atactgtaaa ttaaaattgt
    21061 cagtgtatat tttttaataa ctctattagg aaacaatagt tcatctatta ggttcttttt
    21121 caccagtatc tctcgttcaa ttctatcttt gtcacagatt ttgattttac tattttttat
    21181 tttttcctct aataaaataa cctcgaacga tctgctaatt tttaataaat atgcaggaaa
    21241 agctaatgtt aagcataatg taattaattc atttacattg ttcatgtaac ttataaaata
    21301 gatgaaagtt gctactagtg ctcctaaaaa tatagttata ttaagttcta catcaaatat
    21361 tttaaaaata tctgctctat tcatcagtta atcatccttt caaggtttat taatactaat
    21421 aaattattag atataggtat atcatattat taatttaaga aattgtcttt tataatttta
    21481 cttaataata aaaaagtaga accatttaaa attaatggtt ctacttttta actattacta
    21541 attttaaaaa taaactaatc tacaatatct aaaaatatat gtttagtact atttttgttt
    21601 agttatatca agtgatttgg gaattaacaa atagacaact attgaaatga taatcatgat
    21661 aatcccacct actaaagcag ttgctacaaa agcatcatta aatgatgtta cagcctcgtt
    21721 tgcaagctgt tttatccccg tagctttagc tacttcgaca gcgcccacta cagattcttc
    21781 agctacatga gctaaatctc caactatacc ttttgatgaa aaagatgaaa tatctaaaaa
    21841 tacacgataa agcatagaag ataggctacc aagtactgct acaccaaaaa catttccaag
    21901 gtcatacata gactcttcaa cagcagctgc attacctgct tttgatgtag gtgtttctaa
    21961 cattattaga gcagatgcaa ctgctagtga agccgtacca gctccaacta aaattaatgc
    22021 taaagccatt gtagaatatg ataatggatg accaaagaaa tacataataa acatgccaat
    22081 ggctgcaatt ccaattccgg aaggtaacac tattttcggt ccaaatcgcg ccgctaatcc
    22141 gggtgcaatt ggtgcaaaca ccatatctcc tattgccata ggtaataggt ataagccagc
    22201 tttaaaagga gaaagttctt ccacaacctg taaccattgt gaagctaata acaaaacaga
    22261 tgtcattgca aacattgtca taaatgcagc aattgtacca gctgaaaatg atctcttttt
    22321 aaaaagtctt acgtctaaca ttggatcaga acttgataaa ttacgtttaa caaatatcac
    22381 tatcatggta attgctaata ctattacaac ccatggaata atatctgcta gtccttcttt
    22441 tgaaaattct ttgatactcc ataccagtcc aatcatgcct gcaattgata aaattgtaga
    22501 aggaatatcc cacgagtgag acttttcttt tgataactta gactctggta ataaaaataa
    22561 acctgctaca attgctatta tcacaaacgg tacattaatt aaaaatgccg agtgccatga
    22621 aaattgctca agtaaagctc ctccgataat tggtccaaaa acagcaccta tcgatgaaac
    22681 gattgaccat acagctaatg cagtggccct ttctttaggg ttttcaaaaa ttactcttat
    22741 cattgaaaga gtagttggca ttattaaagc acctgcaata ccaagtaaaa atcgaatagc
    22801 tattacgaac tctgcacttt ctgcgaaaaa tatagctaat gaaacgaggc caaataaagc
    22861 aaatccagtt aataatgctt tttttcttcc ccatttatca gcaaaggcac tcaatggaat
    22921 tataaagcca gctaaaacaa gagagtatat atcaactatc cataactgtt gggtaccaga
    22981 aggctctaac tctcttacta attccggtaa agccataatt aatattgtca tatccattgt
    23041 aacaacaaac aaactaacag ctaatactac tagtgcagtc catctttttt ttgatgtcat
    23101 catatcagta gtttttgtaa aaaatgaaat catttaagtt ccctccaatc cttatagacc
    23161 gttcgatcgg tctataagga ttataatcta tttttttaca tattacaaca aaaaatcttg
    23221 cgaaatttaa atggctgtat tgtgttatac aattattctt tgaatttttg tgctatcatt
    23281 gatagtactt aatactcatt aaaggcgtga tgaacttgaa agataaaata ctaggtgtcg
    23341 caaaggaatt atttataaaa aatggatata atgccactac tactggagaa attgttaaat
    23401 tatcagaaag tagtaaaggg aatctttatt atcactttaa aacaaaagaa aatctatttt
    23461 tagaaatttt aaatatagaa gaatctaaat ggcaagaaca gtggaaaaag gaacaaatca
    23521 aatgtaaaac taatagagaa aaattttatt tatataatga actatcttta acaaccgaat
    23581 actattatcc acttcaaaac gcaataattg aattttgcac tgaatattat aaaactaata
    23641 gcattaatga aaaaatgaat aaattagaaa acaaatatat agatgcttat catgtaattt
    23701 ttaaggaggg taatttaaat ggcgaatggt gtattaatga tgttaatgct gttagtaaaa
    23761 tagcagcaaa cgctgttaat ggaattgtta cctttacaca tgaacaaaat attaatgaaa
    23821 gaattaaact tatgaacaag ttctctcaaa tttttttaaa tggacttagt aaataattat
    23881 atatatattc ttgaaatacc aataaatatt atttctaaat tacgttcatt attgataaaa
    23941 aatttaaata gtattactac acaaaaagag agtgcgaatt cgcactctct tttttcttgt
    24001 ataattatta aaagatcatt tcaataatat aatatgagtt ttgagactct gtgagagcct
    24061 cttatttgca ttgacgaccc atttatcaag atgatccctt atcatgctta attctataaa
    24121 ctgtctgtct tgtgatatta acttctttcg caatcttact aattgctttc ccttcttcta
    24181 acatttccac cacgcgatga taaataatac gtttctgtgg gtctttggca tttggtgaat
    24241 aaagtaaggg gcgcccttta tatacgcctt tttccttcgc aacttgaatt ccttgcgctt
    24301 gtcgacgttt actttcattt ctctcttgtt ctgaaaccat tgctaaaatt tgaacgatta
    24361 aatctttcat aaacttatcc agtaatggat tgccaatcac ttcattcatc ataggtaagc
    24421 tggtaatcat taactgaacg tctttctctt ttaaataact cacagtttca ataatttcat
    24481 cataatcacg tcccaaacga tcaatagatt ccacaacgaa tcgatctccc attctgacaa
    24541 aattgagtgc ttcttgaaat acaggtctat tttccactga ctttcccgac tgtttctctg
    24601 taaagatttt ctccacacca aacgtcttta aattatccaa ttgtctttct aaattttgat
    24661 ctatcgatga tactctcgca taacctataa tcattcatct tcactccata attaatatac
    24721 accctaatca tacgttctaa ttgcgataat ttcaacaact tattttgtat gattagggtg
    24781 tacgccaatc atacaattaa agttataaat attaaataaa ctgaaagcgt aaaaatgata
    24841 taataaaatc ataattcttg aggaagcgaa gtgacttatg aatctagcaa tttgcaacta
    24901 aatagtaaac ggattttggt ttattatcgg agttttttta tcatcgatta tactaattcc
    24961 atttgaagac actttactac aatctttacg taactattgg ttactgctcc aaaagagtgt
    25021 agtaaaagga actgctataa aatgcaacgt ctatcctcat atggacagta ttgaaaatgc
    25081 atgtttaatt tcacaaatca cttttaaagt caattcacct tataaaaata tgtctgaaga
    25141 ttatatggat attaaagaat cagatcgaat tatcatgaaa gctatactta ataagtgtgg
    25201 tatagattta caaaaaagta accataagtt aaacaatgtt atgccaagtt acaatgtttt
    25261 tatccgtaaa gacgagttag attatagata gaaataatat tcaaaagaga aatgaatgag
    25321 gactttgcat ttctccactc accgatgtta taatttagtt aacaaggaaa ctagcataga
    25381 tgcaccaatc ccctcactac ggcaatagtg aggggatttt ttaggtgtgg ctatggtcgc
    25441 ctatttatta ttgcgattac gtagccaatg cgtaaataac gcaataatac aaccactgat
    25501 gactgtggtc gtgatgtgaa caaggatttc tagcatagat tagcacctcc tctctgcgtc
    25561 ggaattgacg cctgagagat agacgacttg tatattatat catctacgaa tatacgatga
    25621 taggtagctt ctgataagtg atctggttct gttgcaaagt tgaatttata gtataatttt
    25681 aacaaaaagg agtcttctgt atgaactatt tcagatataa acaatttaac aaggatgtta
    25741 tcactgtagc cgttggctac tatctaagat atgcattgag ctatcgtgat atatctgaaa
    25801 tattaagaga acgtggtgta aacgttcatc attcaacgat ctaccgttgg gttcaagaat
    25861 atgccccaat tttatatcaa atttggaaga aaaagcataa aaaagcttat tacaaatggc
    25921 gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat cgtgccattg
    25981 atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat cattcagcat
    26041 atgcgtttat caaacgtctc attaaacaat ttggtaagcc tcaaaaggta gttacagatc
    26101 aggcaccttc aacgaaggca gcaatggcta aaataattaa agcttttaaa cttaaacctg
    26161 actgtcattg tacatcgaaa tatctgaata acctcattga gcaagatcac cgtcatatta
    26221 aagtaagaaa gacaagatat caaagtatca atacggcaaa gaatacttta aaaggtattg
    26281 aatgtattta cgctctatat aaaaagaacc gcagatctct tcagatctac ggattttcgc
    26341 catgccacga aattagggat atgttagcca gttaa
//
