LOCUS       CP152359               20731 bp    DNA     circular BCT 29-APR-2024
DEFINITION  Staphylococcus aureus strain BSN137 plasmid pSR01, complete
            sequence.
ACCESSION   CP152359
VERSION     CP152359.1
DBLINK      BioProject: PRJNA1048360
            BioSample: SAMN38637716
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20731)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN137 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20731)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN137
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: CP043386, CP019564, CP012118, CP014445
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/24/2024 07:41:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,779
            CDSs (total)                      :: 2,697
            Genes (coding)                    :: 2,626
            CDSs (with protein)               :: 2,626
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 47 of 71
            Pseudo Genes (incomplete)         :: 27 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 14 of 71
            ##Genome-Annotation-Data-END##
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20731
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN137"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSR01"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-10-02"
                     /collected_by="Andrew D. Berti"
     gene            complement(join(19118..20731,1..144))
                     /gene="blaR1"
                     /locus_tag="UXR09_13770"
     ARG             complement(19122..20731)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.16"
                     /coverage="91.79"
     gene            251..1096
                     /gene="blaZ"
                     /locus_tag="UXR09_13775"
     ARG             252..1093
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            1465..2073
                     /locus_tag="UXR09_13780"
     CDS             1465..2073
                     /locus_tag="UXR09_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAE99192.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            2487..2780
                     /locus_tag="UXR09_13785"
     CDS             2487..2780
                     /locus_tag="UXR09_13785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="XAE99180.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            2855..4789
                     /locus_tag="UXR09_13790"
     CDS             2855..4789
                     /locus_tag="UXR09_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="XAE99181.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            4793..5104
                     /locus_tag="UXR09_13795"
     CDS             4793..5104
                     /locus_tag="UXR09_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="XAE99182.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            5116..5742
                     /locus_tag="UXR09_13800"
     CDS             5116..5742
                     /locus_tag="UXR09_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="XAE99183.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            5980..6258
                     /locus_tag="UXR09_13805"
     CDS             5980..6258
                     /locus_tag="UXR09_13805"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="XAE99184.1"
                     /translation="MSYSIIRVVKVKSKTNTRGIQRHIQRENKNYENIDIDLSKSYLNY
                     DLVNDTKFDFNKKIDEKIEKNYKGKRKIRTDAIKHIDGLITSDNVFF"
                     /name="plasmid recombination protein"
     gene            6311..6610
                     /locus_tag="UXR09_13810"
     CDS             6311..6610
                     /locus_tag="UXR09_13810"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="XAE99185.1"
                     /translation="MEEEYGKENLLYATVHMDEITPHMHYGVVPITKDGRLSAKEVVGN
                     KKALTEFQDRFNTYINKQGYDLKRGISRQLTKEKHDQVSRYKQKTEYHKQMHMR"
                     /name="plasmid recombination protein"
     gene            6704..7249
                     /locus_tag="UXR09_13815"
     CDS             6704..7249
                     /locus_tag="UXR09_13815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="XAE99186.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKYKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="recombinase"
     gene            complement(7291..7575)
                     /locus_tag="UXR09_13820"
     CDS             complement(7291..7575)
                     /locus_tag="UXR09_13820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE99187.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            7633..8493
                     /locus_tag="UXR09_13825"
     CDS             7633..8493
                     /locus_tag="UXR09_13825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="XAE99188.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            8580..8921
                     /locus_tag="UXR09_13830"
     CDS             8580..8921
                     /locus_tag="UXR09_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="XAE99189.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDACFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(9160..9231)
                     /locus_tag="UXR09_13835"
     CDS             complement(9160..9231)
                     /locus_tag="UXR09_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAE99193.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            9380..9565
                     /locus_tag="UXR09_13840"
     CDS             9380..9565
                     /locus_tag="UXR09_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE99190.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(9784..10527)
                     /locus_tag="UXR09_13845"
     CDS             complement(9784..10527)
                     /locus_tag="UXR09_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="XAE99191.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            10938..11614
                     /locus_tag="UXR09_13850"
                     /pseudo=""
     CDS             10938..11614
                     /locus_tag="UXR09_13850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            11625..11907
                     /locus_tag="UXR09_13855"
                     /pseudo=""
     CDS             11625..11907
                     /locus_tag="UXR09_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            13118..13735
                     /gene="cadD"
                     /locus_tag="UXR09_13860"
     ARG             13119..13732
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            13754..14101
                     /locus_tag="UXR09_13865"
     CDS             13754..14101
                     /locus_tag="UXR09_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="XAE99172.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            14270..14362
                     /locus_tag="UXR09_13870"
     CDS             14270..14362
                     /locus_tag="UXR09_13870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAE99173.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            14574..15548
                     /locus_tag="UXR09_13875"
     CDS             14574..15548
                     /locus_tag="UXR09_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="XAE99174.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(15668..16483)
                     /locus_tag="UXR09_13880"
     CDS             complement(15668..16483)
                     /locus_tag="UXR09_13880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="XAE99175.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(16476..17919)
                     /locus_tag="UXR09_13885"
                     /pseudo=""
     CDS             complement(16476..17919)
                     /locus_tag="UXR09_13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(17891..18484)
                     /locus_tag="UXR09_13890"
     CDS             complement(17891..18484)
                     /locus_tag="UXR09_13890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAE99176.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(18748..19128)
                     /gene="blaI"
                     /locus_tag="UXR09_13895"
     ARG             complement(18752..19128)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     ARG             252..1096
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             1..7780
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          11965..12112
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          7634..8493
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9785..10527)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5981..6255
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="6.520000000000001e-58"
ORIGIN
        1 aattaatcca gcaagcacag ttagatacca aactttataa tttaaactat aattaaaata
       61 gcgttttaat atgtacctaa aaaatactaa caatagaaat ataaaacaaa agcttactac
      121 actcattatt agtaatttag ccattttgac accttctttc aaatatttat aataaacaat
      181 tgacatcaat attacaattg taatattatt gttttgtaaa aattacaact gtaatatcgg
      241 agggtttatt ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg
      301 taattcaaac agttcacatg ccaaagagtt aaatgattta gaaaaaaaat ataatgctca
      361 tattggtgtt tatgctttag atactaaaag tggtaaggaa gtaaaattta attcagataa
      421 gagatttgcc tatgcttcga cttcaaaagc gataaatagt gctattttgt tagaacaagt
      481 accttataat aagttaaata aaaaagtaca tattaacaaa gatgatatag ttgcttattc
      541 tcctatttta gaaaaatatg taggaaaaga catcacttta aaagaactta ttgaggcttc
      601 aatgacatat agtgataata cagcaaacaa taaaattata aaagaaatcg gtggaatcaa
      661 aaaagttaaa caacgtctaa aagaactagg agataaagta acaaatccag ttagatatga
      721 gatagaatta aattactatt cgccaaagag caaaaaagat acttcaacgc ctgctgcttt
      781 cggcaagact ttaaataaac ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt
      841 cttacttgat ttaatgttta ataataaaaa cggagacact ttaattaaag atggtgttcc
      901 aaaagactat aaggttgctg ataaaagtgg tcaagcaata acatatgctt ctagaaatga
      961 tgttgctttt gtttatccta agggccaatc tgaacctatt gttttagtca tttttacgaa
     1021 taaagacaat aaaagtgata agccaaatga taagttgata agtgaaaccg ccaagagtgt
     1081 aatgaaggaa ttttaatatt ctaaatgcat aataaatact gataacatct tatagtttgt
     1141 attatatttt ctattatcgt tgacatgtat aattttgata tcaaaacctg attttccctt
     1201 tattattttc gagatttatt ttcttaattc tctttaacaa actagaaata ttgtatatac
     1261 aaaaaatcat aaataacaga tgaatagttt aattataggt gttcatcaat cgaaaaagca
     1321 acgtatctta tttaaagtgc gttgcttttt tctcatttat aaggttaaat aattctcata
     1381 tatcaagcaa agtgacataa ttgttgaatt tatagtaact gaaacgtatg attagggtgt
     1441 atattaatta tgagatggaa atcaatgatt gttggctatg cgagagtatc atcgaacgat
     1501 caaaatttag aaagacaact tgaaaattta aagacgtttt gtgctgaaaa aatatttaca
     1561 gaaaaacagt ctgggaaatc tattgaaaat agaccagtac ttcaagaagc acttaacttt
     1621 ttgaggatgg gagatcggtt tgtagtagaa tccattgatt gtttaggtcg taattatgat
     1681 gaagtgattc ataccgttaa ttatttaaaa gacaaagaag tacaattaat gattactagc
     1741 ttacctatga tgaatgaagt ggttggcaat ccattactgg ataagtttat gaaagattta
     1801 attattcaaa tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa
     1861 gcgcaaggaa ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc cttactttat
     1921 tcaccaaatg ctaaagatcc acagaaacgt attatttatc atcgcgttgt agaaatgtta
     1981 gaagaaggcc aatcaattag taaaattgcg aaagaagtaa atataacaag gcagacgatt
     2041 tacagaatta aaaacgataa tgatttgatt taataaactt tgtttcaatg caactgagag
     2101 cttctcacag cgtctcaaaa cagatgatta taatctatta tgagttttta ataataagac
     2161 aagaaaagag agcgtaaata tgctctctct ttttctcatt aacgaacgtt tataacgcaa
     2221 tcatgatgag agtattaata cagttaatta tttgaaatac tttagtttat ataatgttga
     2281 attataggta gtgaaattgt atttattata cattgtcata tcgttgttta atgatagtta
     2341 atttaaggat aatagaatta atattatata tagatgaaca aaacaagcaa cagagcagaa
     2401 aaaacacttt tagattattt ttactcattc tctattttat ttatttttgc tataataaat
     2461 aaagaatatt aaatggaggt gtttttatga aaaagaaatt tgtttctagt tgtattgcta
     2521 gtacaatctt attcggcact ttattaggtg taacttataa agctgaagct gcaacagtac
     2581 atgtagctgg tggtgtttgg agccatggta ttggaaaaca ttacgtatgg tcttattata
     2641 gtcacaataa aagaaatcat ggttcaacag cagtagggaa atattcatct tttagtggtg
     2701 ttgctcgacc tggtgttcaa tctaaggcat ctgctccaaa ggcttggggt ggaaacaaaa
     2761 cattttatag tcttcactaa ttacatatat taattaagga gaatagacag aattaagtaa
     2821 acttaattct gtctattctc ttgaaagagg caatatgaaa aaattcaaat tatttttaga
     2881 ttttagtact ttattattaa tttcagggct attattttta tttttcttca aagaaaatga
     2941 agaaattata cctgaaagtt ccaatatttt aacaatctct aattgggata aatctaacag
     3001 taaatcaaaa gtgttagatg tcattgaatc aggcgccaaa aatcaaaata tacaaataat
     3061 taaatccgtt aaagattttg ataataaaaa agaatttttt gttttcaact caaaacgaaa
     3121 taattctgac tttatacgta ataaaacatc acttttaact ccatcagatt tattaaacag
     3181 agagataaaa ggaaagtatt atattattgg tgaacatttc aatgtagaag agcttacgag
     3241 tgaattaaaa aaagctggtt taacatctga agttgaatac ataaatagaa acatattatt
     3301 ttttgaatta gtcatagata atgatttatt agtgcctttc atattcttag gcgtattata
     3361 tcttttgtac ttcttatatg acagaggata taatttgaaa ttttatgcta ttcaaaagct
     3421 acatggcttt tcaactacac gcattatttt tcataatatt catataaaaa tcatttattg
     3481 gctagtactt accgctattt tctttattgc taatatatta atcattcata tagccaattt
     3541 agaattggat ttcttaatgt ttattcgtag atttatcgtg ttgctttttg tttttgcttg
     3601 tattactaca ttgctgtggc tgatttcgta tagtcttctt ttgaagttaa gtattccatt
     3661 aatcttaaaa gggaaaaaag gatataagtt ttcaatattt atgggtacct tcaccaaatg
     3721 tatcatggtg ctaatactat cttttttact ggcacaaaat ttaaatgctt atacgaagtt
     3781 aaagaatata tatgactctg aaaaaatctg gcaaaagtta gataattact atacattaga
     3841 gatttctcct aatattagaa attcagaaga aaaacaaatt ttagaaacta atatatacaa
     3901 tttaattaag aaaagcgaac aacttggtgg attgctttta aagaataata atatagccaa
     3961 tcccgataaa aacaattaca ttcctgaaaa tggcaatgtc ttttttatca ataacaattt
     4021 tctgaatttc tataaaaata taaatcatga ttttaaaatg attgacaatc attcggataa
     4081 aataaacgtg tttattcctc caaggttaca atatcaaaaa tctgaaattc aaaaaaatca
     4141 ccaaggatgg attgactttc aaaagcaaca aaacaaaaaa gtagatgtgc aagtactgtc
     4201 aaaaaacgta tctgtttttt cttttgatcg cacaactaat ttgaaatttg ggtatctaga
     4261 ttctccaata gtaatgttgt tgacacttga cgatttaaca ggagattttt atttagctgc
     4321 tgtttctcaa ggtggatatc tatttaaaga tttagataca cttaaacagt tgcttaaaga
     4381 taatcaccta gaagaagaaa ttagcggtat aactaattac aaggattctg tgttaaatga
     4441 attaaatgaa acgaaaacaa aaatgataat aacaatagtt actattatta ttaacgtttt
     4501 cattcttttg atagctactg tatttgaaac aattcaatat tttagctgga ataaaaagca
     4561 actattatta agaaaaattc atggttattc attattcagc agtaatgtac gttatttaac
     4621 aatttctatc ttactttcta ttatgttagc ttacactacg catattttat ttggttcaaa
     4681 gatattacta ttcataataa tgtctattgc tattattcaa catttacttc aaattgctta
     4741 tattaaatat cttgaaaaat actttaaaga tttaatgagg gagatttaaa caatgaaaag
     4801 aactttaatt attgtaacaa ttgtactatt aatcatcata cttagtctgt tattggttag
     4861 aaatgagcat ttagatcgtt ttaacccact gttaaaagaa aaagtatctt atgccaaagt
     4921 tccaaaagat acccaggact atagaaatat aactgtatac tctaaaaatg gagaaaaaaa
     4981 gagttataaa ttggattttt taggttatga tcctacaaaa gaatatgtga aagtaaatca
     5041 taaagggaaa tatgtgcgtt cgatagaata cattacaaaa gatattccta gctttttaaa
     5101 atgaggtgac cgatagtgat aaaacttgaa aatgtttttg taaaaaaagg taataaaaac
     5161 attttagacg gatgtaactt taattttgaa aaaggaaaat catatgcttt agttggagaa
     5221 agtggcgctg gaaaatctac tttacttaac ataatcgctg ggttcgaaga tgtatcacaa
     5281 ggaagcatat atattgaaga taagttacta aaaaagaaag tcgattttta tagatatacg
     5341 ttagggtatt tgtttcaaaa ttttgcttta cttgaaaatc aaacaatcag tcaaaattta
     5401 gatttagccc taaagttcaa aaagaataaa aaagataata tgaacttaaa gaaagaagta
     5461 ttaaaaaagg tcggcctaga tttagatatc aagagaattg ttagttctct aagcggtggt
     5521 gaacaacaaa gagtagcatt ggcaagatta atattaaaag atccgaaaat cattttagct
     5581 gatgaaccta ctgggtcact agatacgaaa aatggaaaaa tagttattga tttattattg
     5641 aagctacttg atgaaaataa aactatgatt gtcgtaacgc atgatttaga gcttgcgaaa
     5701 cgatttgatg tcatagtcaa tatttctgag cttagaagtt aagaaatatt gataggtata
     5761 gccatacata gagaaaaaac aatatgaaat atgattagtc attacttttg agttttttaa
     5821 tttaaggact ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca
     5881 cacgttttta atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt
     5941 ttaggtgtta taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga
     6001 gttgttaaag tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa
     6061 aataaaaatt atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta
     6121 gtcaatgata ctaagtttga ttttaataaa aaaattgatg agaaaatcga aaaaaattat
     6181 aaagggaaac gcaaaattag aacagatgcc attaaacata ttgatggatt aattacatca
     6241 gataatgtgt ttttttaatc aattatctga agaagagaca aaatagtttt ttaagcatgc
     6301 taaagcgttc ttggaagaag aatacggtaa agaaaatctt ttatatgcga cagtacatat
     6361 ggatgagata acaccacata tgcattatgg cgtagttcct attactaaag atggacgttt
     6421 aagtgcgaaa gaagttgtag gtaataaaaa agcattaacc gaattccaag atagattcaa
     6481 tacgtatatt aataagcaag gctatgattt aaaacgagga atttctagac aacttacaaa
     6541 agaaaaacat gatcaagtta gccgttataa acaaaaaaca gaatatcata aacaaatgca
     6601 tatgcgctag aagcaaatag aggattattt aaagcaagaa aatgataaat tgatacaaaa
     6661 ctaccaaaaa tcattagata cgcttaaaaa gcttctgagt gtcatgtatg aaattaaaac
     6721 taaaaatgta ggtggatggt ttcataaaga gaagcaagaa acaggcaata ttgtaattac
     6781 taaaactgat tttgaaaaat acactaaaca aattaaagca gcacagatga tattagatga
     6841 ttatgaatgt attaaaagtg ggaagtcatt aaaaaaagca gagaaacaaa atgaaagttt
     6901 agttaatgaa ttgactagtg tccatatgga aaatgaaaag ctggttgaag aatttaatga
     6961 tttagcacaa cgttataatt atttgttgtc agagaatgaa aagaaatata aagaactaaa
     7021 ttatacgctt aagttattca atcaagtttt taaaatcatt aaaagtatga tgaaagaaga
     7081 gcgttatcat acactaataa atcatattga taatcattta gacaattcta aaatacgtga
     7141 agtaatgacg atagataaca atgatgaaca gttctttaag aagaaatatc aagcacaaga
     7201 acgagaaatc atttttaaag aagatagaga agatggttat acattataaa aatagatatt
     7261 taaatgcatt tgtttgaggt taattatttt ttaggatgaa aaataggtag cccccctcga
     7321 actttttaat atatttttat aaatcttttt aaaaaccttt ttaggggctt gttcagccct
     7381 agaacaacaa gggatttcaa tgcctaaagg agtgtttttg ccacataaaa ggagtgtttt
     7441 tgccacataa aaggagtgtt tttgccacat aaaaggagtg tttttgccac ataaaaggag
     7501 tgttttaaaa agttgtactc cttttatggt ttgacattga taataaagta gtttattgtg
     7561 aataaaagtt ttcaaatggg agtgtatatt caaacgatac tcctttaggt tcgtaataaa
     7621 gggggctgta tcatgacagg agagacagtt gtatataaaa atgaaatgaa tttagttcca
     7681 ttaaggcgat ttacagctac tgaaattaat ttattttttg cgatgtgtaa taaattaaaa
     7741 gagcaagata ctaatacatt acgtttgtct tttgatgaat taaaaaaatt aagtaattat
     7801 agtccagaaa cacgtaatat taatagattt gctaatgatt tagataatgt gtataaaaag
     7861 atgttgaatt taaccattag atatgaagat gatgatgtaa tagaaagatt cgttttattc
     7921 aatcattata gaatccataa gcgagaacaa tatctagaaa tatcaacttc ttcaaattta
     7981 aaacacatat tgaattcaat tactaataat tttacaaaat ttgaattaaa agaaatgact
     8041 aggcttaaat ctacatattc taaaaatatg tttagattac ttaaacaata caaacataca
     8101 ggctatttaa aaattcacat cgatgatttt aaaaatcgtt tagatatacc taaatcttat
     8161 cgtatgactg atattaacaa aaatgttttt aaacctatta ttattgaatt aggttctata
     8221 tttaataatc ttactatcaa taaaatcaaa gcgaaaaaag ggcgtaaaat tgaatggata
     8281 gagttcacat ttgacgctga gaaacgcatt cataacaaac gacaacctca aatgtccaag
     8341 atagataaat caagacaata tgtgaggcgt gaaaagacgc ctaaatggtt agaagaacgg
     8401 tcatatgaaa agcaacctca aaaagattac gacccacaat tagagaaaga acgagaggat
     8461 tttttaaaac aacttgaact gaattgggaa taacgcaact tttcgttgcg agttggttaa
     8521 ctaaaagtat cgtgactttt caattatttt aattatagtt tgagttaagg agtgatttta
     8581 tgaaattagc tgaagctata aaagaacaga gagaattaaa aggatggtct caagaggaat
     8641 tagccaatat attaaaggtt tccagacaaa gtgtttctaa atgggaaagt gccaaaaact
     8701 atccttcctt agatattttg attgctatga gcgatttatt cggaatctct ttagagcatt
     8761 taattaaagg agatgcatgt tttaaaaaag ttattttaga gggaaattat agagagagta
     8821 acagggtacc ttccatagtt gattttcttt atgatttttg gtggcttttc tttcctgttg
     8881 ccggattttt agtttgggcc attcattcgt tcatgggttg attttaaaat caaaatttaa
     8941 tgcacatcag gcaatatgaa aaaggaaagt atttttacga caccttgaaa tgtattgata
     9001 agaatagaag agtttacaaa aggcaatatg aaatatatac taaaagtaac aagaatttcg
     9061 ttggtaaacg cacaaaaccc cgaactattc gccgtagttc ggggttttgt ggtgaattgg
     9121 ctttaatcgt ctatattatt ttttatcacg tttatggagc taataaccaa ataacgtaac
     9181 gagacaacca ctgattgccg ttgtcatgat gtgaacaaga atttcattca taaatcgcac
     9241 ctcctctcta cgccgaattg acatctgaga gatagacgac cttcacatta taacaaatct
     9301 ctccttccat gaaataacat gaatattaat aaatgttgtt atatattaaa gataaataaa
     9361 tataagggtg ggattgataa tgtttggcga tcaaagacaa gaagctacaa aatatgtcat
     9421 taaagaaggt tatcaagata tttatttcct caacaaaaac ggggaatggt attatttcga
     9481 agtaagaagt gtctggcgtg gcaaacatat tattagagtt aaagatggtt tgttaggttg
     9541 gagaaaagaa atagtaactg aataaagata caaaatactt gccaatgcaa aagaatgaaa
     9601 acgcgtcaaa tcaacgatgt ataaaagatg cataaaagat aatgaaagta aaaagccata
     9661 aatgccgtca tataggcatt tatggctttt tgtttggtta acataatcga tgattatcag
     9721 aagttcaatt cacataaaaa agcacggcta atttatgaac ttgtcgtacc tttttaatta
     9781 aaattagtta ccaaatagac gactccaaaa ccccttttta ggttccgttt cttcactctt
     9841 ttcttctata tcactatcat tgtcatttgg attagctgaa acgtcttctc tttgtgcttc
     9901 ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt gaatctctgt
     9961 ttctttagtt tcttcctgat ctcggttaat atttacagga ctagtagtat atgttttttc
    10021 ttgtgcatca acgttttgtc tagcgttagt agatgtatca aagggataat taaggtgttt
    10081 ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta atgccagaac
    10141 ttgctgattc tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa attcaattgt
    10201 tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtattaa tctgattttt
    10261 aagtatttct actatttgag catcgctttt agattcaaaa ttaatattat ccgactcttt
    10321 tttttgtttg tcttcagtag cactttcaaa accatatttc tttttatttt catttactct
    10381 ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt cctgttttat
    10441 tgtctctata ttcaatctct taatattatt aaaaatcgtt tgcttactaa cccctaattc
    10501 ttcactcaac ctttttacac ttttcatatc atcaaccctt tataaaatgt ttataaaccc
    10561 ttagtaaaat attataagct tataacgatt aataataaag taatcgacaa ataaaaatat
    10621 aaattcgcca acctttttat caagggtttg taaagggttt atggtgttta tcaaaggttt
    10681 ataaacctat attttccctt ttttaagttt attcaaagtg ctataataac cttaatataa
    10741 caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta gaaactgttt
    10801 atttatataa ttttcgatac ttagattata taatgaataa tatcttagtg caagcaccta
    10861 gattattaaa taaacacaaa aaatgtaagc gttttattac ctcttaccaa actaaaattc
    10921 ggaaagaggt ttttattatg tcaattaaac tttacaacat aaatgaggaa tacagagaaa
    10981 agttttatca aataccgaaa gtatttttta caaatcctaa atatatcaag ttatccaatg
    11041 atgcaaaaat ggcatggggt attcttagag atcgtttaga tttatcaatt aaaaatggtt
    11101 gggttgattc taaaacaggt aatatttatt tttattacaa aaatgaaaac ccacaaaata
    11161 tattaaattg taaaaaagat aaagtaatta aaataaagaa agaacttaat tgaagccgaa
    11221 ttactactac aagaaagaca aggtttaaat aagacaaata aactttattt agttaaacca
    11281 gaagtaacag aagatgatat ttataaaatt caaaagcaag aaaacactgt tgagagcagc
    11341 aatggcaagg aagtcggaaa aaccgacttc aagaagtcga taaaacagaa tctaatgata
    11401 ctgaacttag ctatactgaa tctaacaata ctgaaataaa tgatatgaat gacttgaatg
    11461 atatagagtc cgaaaatgaa attagtaatc attcaagtca atgcaaggtt atttaatgca
    11521 aacaatttta actgaatttg aagaaacaca tgcactttat atgcgccgta aaaacatgaa
    11581 acaatataat atctttaatc aatcattcaa atgattttat aacaatcaaa gatacatcaa
    11641 aatatttcgt taaatcatct gactttttaa ctgatagcga tgaaaaaatc aagaaattgt
    11701 cagtgatcta gaaaaagatt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa
    11761 ataaaaacat aaaattttaa acttagacga tgctgaagat ggcaatttaa ttaatacaag
    11821 tgatgaagat aaaatagcaa atgaagaaga aaaggcacat tcgattacgg caattttgaa
    11881 aagcaaaatt attatttaag gcattagtga taactgatgt ctttttttat tacttttttg
    11941 taaaaaaagt gctgtcttat ttttgtgaca aatgctgtat gtagtgtcac aaaagtgtga
    12001 cacttgagct ttttatgacc ccacacaaaa acattttcga agccttgaaa tatctggctt
    12061 tgccagatcc cccattcatt gatggggaca aatttccctt atgctcttac ggagatttta
    12121 gagttaaatt aaaatttcta agtttttgat aagaaaagcc ctgcaggaat ttagaagaac
    12181 gtggggaagt tttaaagaat tttatgctaa tttttaattt gcatgtaaat gggcagtgtc
    12241 taaaaaatag ttattgtttt tgctcaaatt tttgtttttg aaaatagcat atatttattt
    12301 ggctcatatt tgcgttttaa aagcgtatat aagttttaga tataaaacta tatgaatcac
    12361 ccctaaatct ttaaaatgcc ctcttaaaat tcaaaataag ggcataaaaa ataaaagccc
    12421 ccccagataa agtgaggtag ctttttcttt cgacgccgta tcgtcgatgt aattcaaaaa
    12481 agttatgggc tataaatcta catcactttt tcaagaatgt agtagcaata ttcaacgcaa
    12541 attaattttt ataactgctc ggaatatctc aagccgtttc tttaattttg aaataaaaaa
    12601 atcgacgaag gtcgattacg tttttgcaca tgtcgattta tccgacgtat aagtgcgccc
    12661 ttacgggatt taactagatt ataacgacga attttagacc tgtaaagcaa taacaattag
    12721 gtctaccagg tagataaagt gtacaaagta gaaccgaaaa agttatttat tttgaagatt
    12781 tttcgtagat ataatttgct aataaacttc ctaaaactga ataaagaaaa atagttaaac
    12841 tcatgtaatc actccataat tctgaagtgt ctccatgtct acgcatagac acgcatttat
    12901 gccgagaaaa tttattgtgc gttgagaaga acccttaact aaacttgcag acgaatgtcg
    12961 gcatagcgtg agctattaag ccgaccattc gacaagtttt gggattgtta agggttccga
    13021 ggctcaacgt caataaagca attggaataa agcacctatg attatttaaa aatataagtt
    13081 ataatacatt caaaaatatt tttgaatgag gtgtattatg attcaaacgg ttgttgctgc
    13141 tgctgttctt tatattgcta cagcagttga tttattagta attttattaa tattttttgc
    13201 tagagcaaag actagaaaag aatatagaaa tatttatgtt ggtcaatatt tagggtctat
    13261 tattttaata ttagttagtt tgtttttagc ttttgtatta aattatgttc cagaaaagtg
    13321 gatattaggt ttattgggtt taataccaat ttatcttgga attaaagtgg ctatttatga
    13381 tgattgtgaa ggagaaaaga gagctaaaaa agaattgaat gaaaaaggat tgtctaaatt
    13441 agttggtacg gttgcaattg ttacgatagc aagttgtggc gccgataata ttggtttatt
    13501 tgttccgtat tttgtgacat taagtgttac taatttatta cttactctgt ttgtcttttt
    13561 aattttaatt ttcttcttgg tgtttactgc acaaaaatta gctaatatcc caggaattgg
    13621 agaaattgtt gagaaattta gtcgttggat tatggctatc atttatatag ctttaggttt
    13681 atttattatt attgaaaatg acactattca aacaatttta ggatttatat tttaatttag
    13741 ggtgtgattt tatatgagtt atgaaaatac ttgtgatgtg atctgtgtac atgaggataa
    13801 agttaacaat gctttaagtt ttttagaaga tgataaatct aagaaattac ttaacatttt
    13861 agaaaaaatt tgtgatgaga agaaattgaa aatcatatta tctttgatta aagaagatga
    13921 gttgtgtgtt tgtgatattt ctttgatatt gaaaatgagt gttgcttcaa cttcacatca
    13981 tttaaggctt ttatataaaa atgaggtact tgatttttat aaagatggaa agatggcata
    14041 ttattttatt aaagacgatg aaataagaga gtttttctct aaaaatcagg agggtttttg
    14101 aaacgagtga aacgagtttc ttcttgtctt gatactataa aaaacaaagt tatataacat
    14161 aagacgactt atcggaagtt atctatcatc gtatattcgg agatgatata atatacaggt
    14221 cgcctatctc tcaggcgtca attcagacgc agagaggagg tgcattactt tgctaatcat
    14281 tttcgttcac atcatagcac cagtcatcag tggctgtgct gttgcgtatt atacttattg
    14341 gcttagtaaa cgcaacaaat aattaatagg cgactttata agccagcatc gaaaaaatcc
    14401 ccacactatt gcagtagtgt ggggattggt gcattaattg ttaatcattt tcgttatcta
    14461 gattataaca ctggttagta gaggaatgca aaaagataat attttaagta gtctttttgg
    14521 atattatcat atgatatatt tatgtaaatt gattttttat taaaggagca tatatgagta
    14581 atactaaaat taaatatcaa atttttattt catcaactta tttagattta atagaagagc
    14641 gtcaagcagt agtagaagca gttttaaaca gtaataatat tccagcaggt atggaacttt
    14701 ttaactcaag tagtaaaagc caatgggaaa taataacaca atggatcaat gaatcagatg
    14761 cagtgatatt attgttaggt tctagttatg gaacaattga tagtgaagaa aatattagct
    14821 atacagaaat ggagtacaat tttgctaaat ctttaggtaa acctatatat gtttttgaga
    14881 tgaataaagc atctaccgaa tccgcggaaa agtctaaaaa attagatgag tttaagacaa
    14941 aagttaaaga aaatagacta attagtccaa atattaatga tatttcggaa ttaaaaagta
    15001 aagtatctca gactttaatg caaagtgtac ctagtgaaat taaagaaaat agtggatgga
    15061 taagagtaca ggattgtggt aaaaatgtaa aaaaattaaa aaaattggat gctatacaaa
    15121 gagatttaga tacatatgat tttttgaaag aagaacttta taaaatattc atgtatgtaa
    15181 aaacttttta tttccagcac acaccatttg atgatagtta tattgaagat atagaaaact
    15241 acctgctaaa ttatgaaaat aatccacata aatcattcat gaaaataaaa gtttatgatt
    15301 ataaaaactt tttaaaacat ttaaaaaaca tattgatttt aattaaacaa ggaaaaaagc
    15361 cattagctca agccggtcat tttaaattaa gcttttacga agaggattta aaattgttac
    15421 aaaaaaatta taagactacg ctagtcgata ttaaaggatt gaataaacat ttttataagg
    15481 aatgtgatag gtgcttaaaa gcatataata tttttattga gggtataaat aaacatttat
    15541 atgaatgata taagtacacc ctaatcatac atatataatt gttgtcactt tactcgatat
    15601 atgagaatga ctttacctaa taaatgagaa aagcaacgca ctatattaaa atgcgttgct
    15661 ttttctatta tcgaatacct ataactaaac tatctctagc tgtttctaca acttctgtac
    15721 ttattttatc taaaccattt atatccataa ttctgtctat ctgcgcaaat aaacgatgaa
    15781 tcagcctaaa attccctttt gtaattttaa taatcgtcgt tattgcctca taatcagtaa
    15841 agtcttcgag ttttaaatca aatcctaagt cttgccactt atattctaat atatgatgcg
    15901 tctcatcttt acttagatta tcaaattcat gcgcaaaacc tatacgcgaa tatagttgag
    15961 gataacgaga tagttttttc tctatacccg gcataccaat aaatatcatt gctaaattat
    16021 gttcatcata aatagctctt aattgctcta aatgttgcac tttaaggcga tcaatctcat
    16081 ctactataat taaatcaata tatttaaaca tatcactata atgtttacta tgttcatgtc
    16141 catacttatt tacaacatgt aatttttgac ccaaatcaat gattgcagta atactatata
    16201 aatcattcct taatttagtt tgtttttctg ctggtgcatt ataaaatatt ttatccaccg
    16261 atagtatgtc atcggtcgtt ttactagcta aatcttccca acctctatgg ttaacttgtt
    16321 tttcaatagt atcccaattt gtgtaatacc tagacgataa agtttttccg acaccaggtt
    16381 gaccataaca tataccaata tactgatatt taatacaagc atcacaaaat tcagcaaagc
    16441 gtttatactc tttcgtttca atgaaatttt gatttttagt cattacgata tctctttaat
    16501 tttttgacgt ttttagtcgt ttcttgaggt gaataaccac aatttttttc ttccttaatt
    16561 aattccgtgg tacttggact agcaatattt tgttttaagt gttttcttct ctgactacga
    16621 gcgtgctgta tgtcttttat atctatggag taatcagcta tttctggaca tatagcagta
    16681 caaagaaatt catctctata aaacacacgt atttcagcca tatcatttgg gttataacga
    16741 atcagtacat attcacctac ataagcttct agattagtat tactgtatcg aaaaccttga
    16801 aaatgaatgc catctgaatg aacttttcta gatttaggta tttccaacaa taataaatca
    16861 agttgttcta agctacttgg catattaggg aaaaagtgat tactattcca atgactgata
    16921 ggcgtggtat gaatagtact atgttctttt tgattataat cttcaattaa aaagtaacgt
    16981 aatttttctt caaaattgtg aaaatttatt agattactag gagtatcatt attgtttata
    17041 tatccaggca gttgttctaa gaaagtttga ttaactgtct gaaagaatcg ttctattttt
    17101 ccacgaccac gaggaacacc aactttcgaa aacatcaagt taattttcaa atcaatagcg
    17161 acttgttcca tatgatgtga agtaaagtca cttccatgat ctgtgtagaa tttttcgggt
    17221 ataccacaca ctggccaatt ggtatcattt ttattccata ttgcttggtg tagtgttaat
    17281 gctgtgtttt gagcattggg gggcatcaaa acttaagaaa tagcctgcaa ttgcacgact
    17341 atagtcatcc ataataatag ttagccatgg tctattgata ttaccttttt ggtctaatat
    17401 aaagatatct agcaaagtat ggtctgcttg ccatatttca ttgggtctcg aggattctct
    17461 aatttgtatt aaatcgtact tattttgata gtatttttca ccctgatgag agaaatcaat
    17521 aacagactta ggcatcgctt taataacact ataaatttgt ttataacttg gtatatcaaa
    17581 attattttct ttacagtaat tagtgatttt cctatgaatt gtggctatac tatttctttt
    17641 attcataagc gcaaggcgtt caatttcatc aattatcttt ggttctattt tacgtgttcc
    17701 tttatcagct cttgtcgcat agattagtcc tttaagtcct tgttctttat atgacttatt
    17761 ccacctataa agggtgctta acgcaatccc tttactttta gaaatacttg ataaagattg
    17821 ttcgcctagg ataaaaggtt ttataatatt gtacttttga gtagcttttt tacgtttggc
    17881 ttcagaaaaa ttagttagat acttctcctt gtttttcatc ttccttgtcc tccaatttat
    17941 tgaggtaacg ataaattgtt gtacgtgaaa catgccactg ttctgcaatt gtcttaattg
    18001 gcgtgccatt atcataaagg gtcttaagta agtttaaatc tttttgattt aatttttctg
    18061 gtctgcctcc atatcggcct ctagcacgtg ctgcaattcg gccagctgaa gaacgctcta
    18121 aaattaaatt acgttcaaat tctgcaaatg ctgcgaataa atgaaataat aattgtccag
    18181 ttgaacttga tttatccatt gttatatttt cttctaaact atggaaactt acacctcgtt
    18241 cgttaagctc attaactaat gtgattaaat cctccatatt acgtcccaat ctatctaatc
    18301 tccaaacaac aatcgtatct cctgacctcg caaattcaat tgctttatct aaaccaggtc
    18361 ttttactttt tgaaccactc atatggtcat taaatatctt ttcacaacca tatgtattta
    18421 atcgatcctc ctgtaaattt aaattttgta atccagttga aactcttgca taacctattt
    18481 tcaaaataca aacctcctat atacatcttc agtgtaccat aacttaatta caaggtcttt
    18541 tatgaacata gattttttgt tgggtttttg aacacataat cctatgtaat tcttacttat
    18601 ttagacataa aagaagagtg tacagaaaat ggttattttc tgtacactct catctttaat
    18661 aatatatttt aaatgtcatt aacaaaacta atttaataag agtcaagcat agtttacata
    18721 tgtattatgt ttgaaacata cctctaatta ctttttacta atatcattta aaatatctcg
    18781 caattcttca atttctttgt tatttaattc ttcatttttc gcaaaattca acactaaact
    18841 tttcatatcc cctccataca gtttattaag aaaggtttta gcagttttca ttttaatatc
    18901 gtcttcttta atatttgatg agtaaaaata aatattttct gatttgtatc gttttataat
    18961 ctctttttta tatagtcttg tgattaatgt tctaatcgtt ttatcactaa cttctttata
    19021 tttttgaatt tcaactacaa tttcattagc tgatactgat tttttatccc atattatatt
    19081 cataacatcc cattcagcca tagatatttc aacttgctta ttggccattt aaaacaccca
    19141 ttccttttaa tattttttca cttattaatt cagcattttt cccagacggg tttccatctg
    19201 ataaatgtgt agcaaaataa tacttatcat gatttgtaat tacgtaacct acaaaccacc
    19261 cattattata cttcccgttt actatacctg tacctgtttt cccatacagt tcatactttt
    19321 catttttctt aatcaataat gaagaagata attgattctt tgctttttta ctaaaatggt
    19381 tattttgttc catcatattt ttaaaaacta ttacttgttc aagattagat attttcaaac
    19441 tatcttccat ccaatagctt ttataacttc ccaaattttc attaccataa tttaattgct
    19501 tgagttgagc cgcagtatag ttctttggta tttgattact aatacgttcg aagtaccaat
    19561 taactgaatt ttgcattgct gtatttaaat cttgttcctt attccaagac tcgaaaagat
    19621 aatgtttatg attccatgac atacgtgaat ttttatcact tataatatga cggtcaagtc
    19681 caaacagtgc taaataaatt ttgtaagttg aatcaggaga atatcttttt ctactttctt
    19741 tttcattata aatatagtat ttgtctttct tcatgctgta cataacgaaa gatccactat
    19801 ttgaaccaaa atttttactt tcatctaaaa tttggtaatc gctttgtaag ggctttttat
    19861 aattataatc agttaaggat tgccccatta aaaactggct ttgaattatc atgataaaaa
    19921 aagtaaaaat acaaataaaa attagaatta attttgactg ctttttcaga tcggcttctt
    19981 ttatattaat taatctattt ttgagtaatg attttttacc attaaatgaa tggcttaata
    20041 tatttttgtt gaaaaatgag gtttttaata cggagtccat aatagattcc gcataagttt
    20101 taaattcatt tttgttaata ttattaagga caaatctatc ggcttctact tcattgtcat
    20161 gaattatctt tctttttaca atatgtacta atggattgta actcataata atagagaaga
    20221 tattaaagat aattaaatgt aaagtatctc tatttttagc atgagcatat tcatgcagta
    20281 ttatatattt tagtctttta tcaattacac ttttaaaata tgaactagga atcaaaataa
    20341 tatatttccc ataccaaaaa gttattggag attgaatagc ctctgctttt cgaatcacaa
    20401 tatttttttt atattgatgg ttgaaaagta tcgtatctat tttatttttt tcattttcgt
    20461 ttagataaag tgactgtttc tttaaatatt taagatataa taaggctttc aaaaatttaa
    20521 aacttaaaat aataactaaa actatccaaa taactgtgca gatattatca attgaatccc
    20581 aattaaactt atggatatct gttgcgaact cttgaacagg tttggtggta attatgttat
    20641 ggttcaagtc gtgtgactta ctttcaactg tgggcgcttg attattcaca ttattaaatt
    20701 ttataaaaga gaatttaatt gggataaaag g
//
