LOCUS       CP152317               27069 bp    DNA     circular BCT 29-APR-2024
DEFINITION  Staphylococcus aureus strain BSN52 plasmid pSAP046A, complete
            sequence.
ACCESSION   CP152317
VERSION     CP152317.1
DBLINK      BioProject: PRJNA1048360
            BioSample: SAMN38637641
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27069)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN52 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27069)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN52
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP043386, GQ900403, GQ900404
            Genome Coverage                   :: 82.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/23/2024 11:26:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,000
            CDSs (total)                      :: 2,918
            Genes (coding)                    :: 2,829
            CDSs (with protein)               :: 2,829
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 45 of 89
            Pseudo Genes (incomplete)         :: 46 of 89
            Pseudo Genes (internal stop)      :: 19 of 89
            Pseudo Genes (multiple problems)  :: 20 of 89
            ##Genome-Annotation-Data-END##
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27069
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN52"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSAP046A"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2018-06-11"
                     /collected_by="Andrew D. Berti"
     gene            join(26860..27069,1..465)
                     /locus_tag="UXQ56_14825"
     CDS             join(26860..27069,1..465)
                     /locus_tag="UXQ56_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="XAE30271.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            606..1241
                     /locus_tag="UXQ56_14830"
                     /pseudo=""
     CDS             606..1241
                     /locus_tag="UXQ56_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1238..1768
                     /gene="sat4"
                     /locus_tag="UXQ56_14835"
     ARG             1239..1765
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            1861..2655
                     /gene="aph(3')-IIIa"
                     /locus_tag="UXQ56_14840"
     ARG             1862..2652
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3137..3612
                     /locus_tag="UXQ56_14845"
                     /pseudo=""
     CDS             3137..3612
                     /locus_tag="UXQ56_14845"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(3671..4345)
                     /locus_tag="UXQ56_14850"
     CDS             complement(3671..4345)
                     /locus_tag="UXQ56_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="XAE30274.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4607..4792
                     /locus_tag="UXQ56_14855"
     CDS             4607..4792
                     /locus_tag="UXQ56_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE30275.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5015..5593)
                     /locus_tag="UXQ56_14860"
     CDS             complement(5015..5593)
                     /locus_tag="UXQ56_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAE30276.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(5858..6238)
                     /gene="blaI"
                     /locus_tag="UXQ56_14865"
     ARG             complement(5862..6238)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6228..7985)
                     /gene="blaR1"
                     /locus_tag="UXQ56_14870"
     ARG             complement(6232..7985)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8092..8937
                     /gene="blaZ"
                     /locus_tag="UXQ56_14875"
     ARG             8093..8934
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9463..9882)
                     /locus_tag="UXQ56_14880"
     CDS             complement(9463..9882)
                     /locus_tag="UXQ56_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="XAE30280.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10006..10977
                     /locus_tag="UXQ56_14885"
     CDS             10006..10977
                     /locus_tag="UXQ56_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="XAE30281.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11149..11241)
                     /locus_tag="UXQ56_14890"
     CDS             complement(11149..11241)
                     /locus_tag="UXQ56_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="XAE30282.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11398..11745)
                     /locus_tag="UXQ56_14895"
     CDS             complement(11398..11745)
                     /locus_tag="UXQ56_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="XAE30283.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11764..12381)
                     /gene="cadD"
                     /locus_tag="UXQ56_14900"
     ARG             complement(11768..12381)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13497..13691)
                     /locus_tag="UXQ56_14905"
     CDS             complement(13497..13691)
                     /locus_tag="UXQ56_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE30285.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13801..14493
                     /locus_tag="UXQ56_14910"
     CDS             13801..14493
                     /locus_tag="UXQ56_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="XAE30261.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14661..14810)
                     /locus_tag="UXQ56_14915"
     CDS             complement(14661..14810)
                     /locus_tag="UXQ56_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE30262.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15357..15646)
                     /locus_tag="UXQ56_14920"
                     /pseudo=""
     CDS             complement(15357..15646)
                     /locus_tag="UXQ56_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15666..16649)
                     /locus_tag="UXQ56_14925"
     CDS             complement(15666..16649)
                     /locus_tag="UXQ56_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="XAE30263.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17075..17818
                     /locus_tag="UXQ56_14930"
     CDS             17075..17818
                     /locus_tag="UXQ56_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="XAE30264.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18045..18230)
                     /locus_tag="UXQ56_14935"
     CDS             complement(18045..18230)
                     /locus_tag="UXQ56_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="XAE30265.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18235..18573)
                     /locus_tag="UXQ56_14940"
     CDS             complement(18235..18573)
                     /locus_tag="UXQ56_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="XAE30266.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(18819..19427)
                     /locus_tag="UXQ56_14945"
     CDS             complement(18819..19427)
                     /locus_tag="UXQ56_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="XAE30267.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(19913..20812)
                     /locus_tag="UXQ56_14950"
     CDS             complement(19913..20812)
                     /locus_tag="UXQ56_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="XAE30268.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20911..22376)
                     /gene="msr(A)"
                     /locus_tag="UXQ56_14955"
                     /pseudo=""
     ARG             complement(20915..22281)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="93.44"
     gene            22850..23524
                     /locus_tag="UXQ56_14960"
     CDS             22850..23524
                     /locus_tag="UXQ56_14960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="XAE30269.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            23582..23959
                     /locus_tag="UXQ56_14965"
                     /pseudo=""
     CDS             23582..23959
                     /locus_tag="UXQ56_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO_process: GO:0006355 - regulation
                     of DNA-templated transcription [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            23956..24837
                     /locus_tag="UXQ56_14970"
                     /pseudo=""
     CDS             23956..24837
                     /locus_tag="UXQ56_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]; GO_function: GO:0004673 - protein
                     histidine kinase activity [Evidence IEA]; GO_function:
                     GO:0005524 - ATP binding [Evidence IEA]; GO_process:
                     GO:0007165 - signal transduction [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            24953..25883
                     /locus_tag="UXQ56_14975"
                     /pseudo=""
     CDS             24953..25883
                     /locus_tag="UXQ56_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity [Evidence
                     IEA]; GO_function: GO:0042626 - ATPase-coupled
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /name="ABC transporter ATP-binding protein"
     gene            25876..26613
                     /locus_tag="UXQ56_14980"
     CDS             25876..26613
                     /locus_tag="UXQ56_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]; GO_function: GO:0140359 - ABC-type
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="XAE30270.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            26627..26803
                     /locus_tag="UXQ56_14985"
                     /pseudo=""
     CDS             26627..26803
                     /locus_tag="UXQ56_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]; GO_process: GO:0016311 -
                     dephosphorylation [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(19917..20812)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(20912..22230)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.41"
                     /coverage="89.96"
     ARG             complement(19914..20812)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1251..1768
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             643..944
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             8093..8937
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(15154..15301)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15360..15535)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(15667..16649)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17076..17818
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacagcaaa gaatacttta
      361 aaaggtattg agtgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accatcattt ttattaaaat
      541 actcttttgt aaaatctttc tgctcttcaa tgtatttaat ttctttacct ctaaatctat
      601 tatagctatt tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag
      661 ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta
      721 aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt
      781 atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc
      841 gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga
      901 gaatgatatc atggaaggtc ggcatcgaaa caggctttaa atgaagtgta ggcaagaact
      961 ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc
     1021 ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg
     1081 cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata
     1141 taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata
     1201 gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg
     1261 gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta agattatacc
     1321 gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa
     1381 aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga
     1441 caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa
     1501 actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt
     1561 cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa
     1621 aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta
     1681 tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa
     1741 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     1801 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     1861 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     1921 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     1981 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     2041 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     2101 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     2161 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     2221 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgctta
     2281 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     2341 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     2401 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     2461 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     2521 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     2581 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     2641 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     2701 gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt tttatatctt
     2761 ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt ggtgaagagg
     2821 tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc agctagctta
     2881 agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat ttgaacagga
     2941 ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaataattc ctgccaaaga
     3001 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     3061 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     3121 cctacttctg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     3181 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     3241 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     3301 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     3361 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     3421 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     3481 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     3541 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     3601 aaacaaatgc tggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt
     3661 cagtgttcgc ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga
     3721 tctgaagaga cctgcggttc tttttatata gagcgtaaat acactcaata ccttttaaag
     3781 tattctttgc tgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat
     3841 cttgctcaat gaggttattc agatatttcg atgtacaatg gcagtcaggt ttaagtttaa
     3901 aagctttaat tactttaacc attgctacct tcgttgaagg tgcctgatct gtaattacct
     3961 tttgaggttt accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat
     4021 ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgcatcaatg gcacgatata
     4081 aatagctcca ttttcctttt attttgatgt acgtctcatc aatacgccat ttgtaataag
     4141 cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct tgaacccaac
     4201 ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac
     4261 gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca tccttgttaa
     4321 attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa
     4381 attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt attaatacaa
     4441 agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac tataggattc
     4501 aacattatat taatcgtttc tttaataatg attatcttct tattttttat aaatcgtagt
     4561 aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga ataaattaga
     4621 aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac ttttatattt
     4681 caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa ctatactaat
     4741 attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt aaaacgttca
     4801 ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt
     4861 attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc agaacgtctc
     4921 ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat aaaattattt
     4981 agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc tcttttgcct
     5041 ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc tctgcaattg
     5101 ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct tgtttattta
     5161 atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga ccggctgatg
     5221 atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata
     5281 attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta tgaaaactca
     5341 cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc cgtcctagtc
     5401 tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt gctttatcta
     5461 aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt tcacaaccat
     5521 atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa actcttgcat
     5581 aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata acttgattac
     5641 gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt ctatgtaata
     5701 cttacttatt tagacaaaaa acaagagtgt acagaaaatg ggttattttc tggacactct
     5761 catctttaat aatatatttt aaatgtcatt aacaaaacta atttaataag agtcaagtat
     5821 ggtttacata tgtattatgt ttgaaacata cctctaatta ctttttacta atatcattta
     5881 aaatgtctcg caattcttca atttctttgt tatttaattc ttcatttttc gcaaaattca
     5941 gcactaaact tttcatatcc cctccataca gtttattaag aaaggtttta gcagttttca
     6001 ttttaatatc gtcttcttta atatttgatg agtaaaaata aatattttct gatttgtatc
     6061 gttttataat ctctttttta tatagtcttg tgattaatgt tctaatcgtt ttatcactaa
     6121 cttctttata tttttgaatt tcaactacaa tttcattagc tgatactgat tttttatccc
     6181 atattatatt cataacatcc cattcagcca tagatatttc aacttgctta ttggtcattt
     6241 aaaacaccca ttccttttaa tattttttca cttattaatt cagcattttt cccagacggg
     6301 tttccatctg ataaatgtgt agcaaaataa tacttatcat gatttgtaat tacgtaacct
     6361 acaaaccacc cattattata cttcccgttt actatacctg tacctgtttt cccatacagt
     6421 tcatactttt catttttctt aatcaataat gaagaagata attgattctt tgctttttta
     6481 ctaaaatggt tattttgttc catcatattt ttaaaaacta ttacttgttc aagattagat
     6541 attttcaaac tatcttccat ccaatagctt ttataacttc ccaaattttc attaccataa
     6601 tttaattgct tgagttgagc cgcagtatag ttctttggta tttgattact aatacgttcg
     6661 aagtaccaat taactgaatt ttgcattgct gtatttaaat cttgttcctt attccaagac
     6721 tcgaaaagat aatgtttatg attccatgac atacgtgaat ttttatcact tataatatga
     6781 cggtcaagtc caaacagtgc taaataaatt ttgtaagttg aatcaggaga atatcttttt
     6841 ctactttctt tttcattata aatatagtat ttgtctttct tcatgctgta cataacgaaa
     6901 gatccactat ttgaaccaaa atttttactt tcatctaaaa tttggtaatc gctttgtaag
     6961 ggctttttat aattataatc agttaaggat tgccccatta aaaactggct ttgaattatc
     7021 atgataaaaa aagtaaaaat acaaataaaa attagaatta attttgactg ctttttcaga
     7081 tcggcttctt ttatattaat taatctactt ttgagtaatg attttttacc attaaatgaa
     7141 tggcttaata tatttttgtt ggaaaatggg gtttttaata cggagtccat aatagattcc
     7201 gcataagttt taaattcatt tttgttaata ttattaagga caaatctatc ggcttctact
     7261 tcattgtcat gaattatctt tctttttaca atatgtacta atggattgta actcataata
     7321 atagagaaga tattaaagat aattaaatgt aaagtatctc tatttttagc atgagcatat
     7381 tcatgcagta ttatatattt tagtctttta tcaattacac ttttaaaata tgaactagga
     7441 atcaaaataa tatatttccc ataccaaaaa gttattggag attgaatagc ctctgctttt
     7501 cgaatcacaa tatttttttt atattgatgg ttgaaaagta tcgtatctat tttatttttt
     7561 tcattttcgt ttagataaag tgactgtttc tttaaatatt taagatataa taaggctttc
     7621 aaaaatttaa aacttaaaat aataactaaa actatccaaa taactgtgca gatattatca
     7681 attgaatccc aattaaactt atggatatct gttgtgaact cttgaatagg tttggtggta
     7741 tttatgttat ggttcaaatc gtgtgactta ctttcaactg tgggcgcttg attattcaca
     7801 ttattaaatt ttataaaaga gaatttaatt gggataaaag gaattaatcc agcaagcata
     7861 gttagatacc aaactttata atttaaacta taattaaaat agcgttttaa tatgtaccta
     7921 aaaaatacta acaatagaaa tataaaacaa aagcttacta cgctcattat tagtaattta
     7981 gccattttga caccttcttt caaatattta taataaacaa ttgacatcaa tattacaatt
     8041 gtaatattat tgatttataa aaattacaac tgtaatatcg gagggtttat tttgaaaaag
     8101 ttaatatttt taattgtaat tgctttagtt ttaagtgcat gtaattcaaa cagttcacat
     8161 gccaaagagt taaatgattt agaaaaaaaa tataatgctc atattggtgt ttatgcttta
     8221 aatactaaaa gtggtaagga agtaaaattt aattcagata agagatttgc ctatgcttcg
     8281 acttcaaaag cgataaatag tgctattttg ttagaacaag taccttataa taagttaaat
     8341 aaaaaagtac atattaacaa agatgatata gttgcttatt ctcctatttt agaaaaatat
     8401 gtaggaaaag atatcacttt aaaagaactt attgaggctt caatgacata tagtgataat
     8461 acagcaaaca ataaaattat aaaagaaatc ggtggaatca aaaaagttaa acaacgtcta
     8521 aaagaactag gagataaagt aacaaatcca gttagatatg agatagaatt aaattactat
     8581 tcaccaaaga gcaaaaaaga tacttcaacg cctgctgctt tcggcaagac tttaaataaa
     8641 cttatcgcaa atggaaaatt aagcaaaaaa aataaaaatt tcttacttga tttaatgttt
     8701 aataataaaa acggagacac tttaattaaa gatggtgttc caaaagacta taaggttgct
     8761 gataaaagtg gtcaagcaat aacatatgct tctagaaatg atgttgcttt tgtttatcct
     8821 aagggccaat ctgaacctat tgttttagtc atttttacga ataaagacaa taaaagtgat
     8881 aagccaaatg ataagttgat aagtgaaacc gccaagagtg taatgaagga attttaatat
     8941 tctaaatgca taataaatac tgataacatc ttatagtttg tattatattt tgtattatcg
     9001 ttgacatgta taattttgat atcaaaaact gattttccct ttattatttt cgagatttat
     9061 tttcttaatt ctctttaaca aactagaaat attgtatata caaaaaatca taaataatag
     9121 atgaatagtt taattatagg tgttcatcaa tcgaaaaagc aacgtatctt atttaaagtg
     9181 cgttgctttt ttctcattta taaggttaaa taattctcat atatcaagca aagtgacaat
     9241 agcattttac aagtattttt tattgttcga ttagggtaaa cctaaataat acataaatta
     9301 tattacaata tgtttattat agaggctaaa gtatcttaga aatttggata gtaggttttt
     9361 cgggaataaa agtatagttg gctttaatat ataattaagc taagctatca tttatattta
     9421 ctcgattata attcgcactt caactttttt ataacgtaaa aattaaaacg tagttttatt
     9481 tatctttagt aatatctttt taaacactac agtttcttca ttagttaaat tagcgaagta
     9541 atgattatta agttgatagg ctttcttttc taatgttggc cataagtctt ttgctttatt
     9601 tgtactgttt attagcacag ttcttctatt ttcattatca gtttgacgtg ttattagatc
     9661 ctttttggac atcttatcta atattccaga tattgttgaa ggttctaaat ttaaagtatt
     9721 accaatcgct ttaggtgtat tcaaattact attaatcaag caattcaaaa caccatattc
     9781 tgctggagta atattatagg gacttaataa acttttaaaa tgtttaaaaa ctctattctg
     9841 agaagtactc aacaaataat ttatacaatt atctaattcc acaactaaaa cctctcttaa
     9901 atcattagta ttgactcgct tatcatatca tgataagttt tgtaggaaaa tagttttgca
     9961 acaaaaacat acttctacaa aacaattgtg aaagaaggct aataaatgtt caatgcggta
    10021 gtagtgagaa aaagtgcatc aaatgttagt tataaagtag aaaaagttga tgaatctcat
    10081 ttatcgaagg gtgatgtatt agtaaaagtg gtatactctt caataaatta taaggatatg
    10141 ctagctttac aatataaagg cggtgtaatt agagattatc ctatgattcc tggtatagat
    10201 tttgcaggta ttgttgaatc aagttcgaat gataagttta aagaaggcga taatgtatta
    10261 gttactggtt atgatgttgg cgtgacacat acaggtggat tttcagaata tgcacaagtg
    10321 cctggagagt ggattgttcc tattccccaa gaaatgtcta ttaaagagtc tatggtatat
    10381 ggcacagccg gttttacggc agcattatca atttttgaac tagaaaaata tggaatgaat
    10441 atcaaatcac aacctgaaat tttagtgtct ggggctacag gtggtgtggg cagtgttgct
    10501 atacaaattt tacataaaat tggatatgaa aatatcactg ctatcgtaag aaaagaaaag
    10561 caaatagaaa tcgcaaaaaa attaggtgca aaacaagtaa taataattga agatgataat
    10621 aaaccgctta aaaaaggtat ttttgattat ttcttagata cagtggggag taatgtaaca
    10681 ttatacggtt taaaacgtct aaattatcaa ggtgttgcta ctgtatgtgg aaatgtagca
    10741 ggaaattcac ttaacgctaa tatattaccg tttattctta gaggtattaa attaattggc
    10801 attgattctg tatatgttga tcataatatc cgtgaagata tatggagtaa gttagcaaat
    10861 gaatggaata taggaaattc acttctatac aatgaaattg gatttgaaga attctataaa
    10921 acgatagatc agcttttaaa aggacaacat ttaggaagaa ctattttaaa agtataagtg
    10981 tgagtattca ttaatacatt tactattaat tcaatcattt tgcatttctc tactaaccag
    11041 tgttataatt tatataacga aaatgattaa caattaatgc accaatcccc acactattgc
    11101 agtagtgtgg ggattttttc gatgctggct tataaagtcg cctattaatt atttgttgcg
    11161 tttactaagc caataagtat aatacgcaac agcacagcca ctgatgactg gtgctatgat
    11221 gtgaacgaaa atgattagca aagtaatgca cctcctctct tcgtcaattg acgcctgaga
    11281 gataggcgac tctattatta taccatctgt gaatatacaa gcatatctac ttccgataag
    11341 tcgtcttatg ttatataact ttgtttttta tagtatcaag acaagaagaa actcgtttca
    11401 aaaaccctca tgatttttag agaaaaactc tcttatttca tcgtctttaa taaaataata
    11461 tgccatcttt ccatctttat aaaaatcaag tacctcattt ttatataaaa gccttaaatg
    11521 atgtgaagtt gaagcaacac tcattttcaa tatcaaagaa atatcacaaa cacacaactc
    11581 atcttcttta atcaaagata atatgatttt caatttcttc tcatcacaaa ttttttctaa
    11641 aatgttaagt aatttcttag atttatcatc ttctaaaaaa cttaaagcat tgttaacttt
    11701 atcctcatgt acacagatca catcacaagt attttcataa ctcatataaa atcacaccct
    11761 aaattaaaat ataaatccta aaattgtttg aatagtgtca ttttcaataa taataaataa
    11821 acctaaagct atataaataa tagccataat ccaacgacta aatttctcaa caatttctcc
    11881 aattcctgga atattagcta atttttgtgc agtaaacacc aagaagaaaa ttaaaattaa
    11941 aaagacaaac agagtaagta ataaattagt aacacttaat gtcacaaaat acggaacaaa
    12001 taaaccaata ttatcggcgc cacaacttgc tatcgtaaca attgcaaccg taccaactaa
    12061 tttagacaat cctttttcat tcaattcttt tttagctctc ttttctcctt cacaatcatc
    12121 ataaatagcc actttaattc caagataaat tggtattaaa cccaataaac ctaatatcca
    12181 cttttctgga acataattta atacaaaagc taaaaacaaa ctaactaata ttaaaataat
    12241 agaccctaaa tattgaccaa cataaatatc tctatattct tttctagtct ttgctctagc
    12301 aaaaaatatt aataaaatta ctaataaatc aactgctgta gcaatataaa gaacagcagc
    12361 agcaacaacc gtttgaatca taatacacct cattcaaaaa tatttttgaa tgtattataa
    12421 cttatatttt taaataatca taggtgcttt attccaattg ctttattgac gttgagcctc
    12481 ggaaccctta acaatcccaa aacttgtcga atggtcggct taatagctca cgctatgccg
    12541 acattcgtct gcaagtttag ttaagggttc ttctcaacat caataaattt tttcggcata
    12601 aatgcgtgtc tatgcgtaga catggagaca cttcagaatt atggagtgat tacatgagtt
    12661 taactatttt tctttattca gttttaggaa gtttattagc aaattatatc tacgaaaaat
    12721 cttcaaaata aataactttt tcggttctac tttgtacact ttatctacct ggtagaccta
    12781 attgttattg ctttacaggt ctaaaattcg tcgttataat ctagttaaat cccgtaaggg
    12841 cgcacttata cgtcggataa atcgacatgt gcaaaaacgt aatcgacctt cgtcgatttt
    12901 tttatttcaa aattaaagaa acggcttgag atattccgag cagttataaa aattaatttg
    12961 cgttgaatat tgctactaca ttcttgaaaa agtgatgtag atttatagcc cataactttt
    13021 ttgaattaca tcgacgatac ggcgtcgaaa gaaaaataaa tagaccgtat gaaagaaaaa
    13081 gctacctcac tttatctggg gtagctttta ttttttatgc ccttattttg aattttaaga
    13141 gggcatttta aagatttagg ggtgattcat atagttttat atctaaaact tatatatgct
    13201 tttaaaacgc aaatatgagc caaataaata tatgctattt tcaaaaacaa aaatttgagc
    13261 aaaaacaata actattttta gacactgccc atttacatgc aaattaaaaa ttagcataaa
    13321 attctttaaa acttccccac gtttttctaa attcctgtag ggcgttttta tcaaaaatca
    13381 agacaagaag aaactcgttc acactcgttt caaaaaaaca agaaatctaa tctatacacc
    13441 taccgttttc caaccccctc aaagcataca aattaaaaac aaaattattc ataatcttac
    13501 tttcttttaa caaaaacata aaaaccataa atagacaaat taactatcaa aggcaataaa
    13561 cagtataaaa aaaccacgaa taaatcttca tcaacatcta aaataaaaaa gaataaaaca
    13621 attaacaaaa tactaattaa caaacctaaa agtggcaaac tttttatata tttttctaaa
    13681 ttttcattca taaaatagac tcctttcaaa aatatgttta taaatatatt aaaataaata
    13741 ttgattttat aaagcgctta cttatacaat taaaatatct tattatcttg gaggtatcaa
    13801 atgaaaatta taaaattatt ttcaataatt tccttgttcc tactggtatt tagcgcgaat
    13861 ttttctaatg cttacgcaaa tgaagaacaa aaaagttctt tactagaaaa tcaaaaagaa
    13921 aaattgaaaa gcaaaaacat cgaagtatca caaatgacca agaaagaaat aagttttcta
    13981 gaacaattgc aaaataaaaa tgaagatatg caaaaattcg aaaagcaaat gaaaaaagaa
    14041 ggatttaaaa aaataaagct agaagacaaa aattctaaat taaaatatct agctacagaa
    14101 gcaaatgata aaaatgcata tggctacata gctaataacg cttataaaaa tgaaaaaaca
    14161 aaagaaattg tagtttctga aacaatatat gataactaca acaaaaaaat cacaaaattc
    14221 attgccgaaa aaagaagtat gactgaaaac aaagagggaa aaatacttat taacaaaaat
    14281 tacgttgaat ataaggctga aaaagttgat aaaaacagac cggtaacata tgcaggattc
    14341 aaatggaacg gcaaagcatt cgcttgtagt atggctggac tttatgcatg tgctcactac
    14401 tgtggagtat gggcaatcgt aaatccaata gccggcggtg tatgtgaagc agtttgcgga
    14461 actgcatttg cagctggatg ctctgtaggt tgattttatt ccaattgttt tattgacgtt
    14521 gagcctcgga acccttaaca atcccaaaac ttgtcgaatg gtcggcttaa tagctcacgc
    14581 tatgccgaca ttcgtctgca agtttagtta agggttcttc tcaacatcaa taaatttttt
    14641 cggcataaat acgatgttcc ttatttatcc tcataaaaaa caatagctga aatatataac
    14701 caattactgt gtgtttgaat ttctaataca tgaatatcat tctttaaaaa cctattaact
    14761 tgtttatcta attgacgatg agtaaaagta gcgaaagttt taatcttcat gatatctctc
    14821 cttttataaa aatagcaatc cttattacaa tattaaacac ttttattttg gattttaaga
    14881 ggcattttga agacttagag gcaaatcata taggttttgt acttaaaaat ctatacagtc
    14941 tcttaaaacg caaatatgag ccaaataaat atatgctaat ttcacaaaca aaaatttcag
    15001 caaaatcagt gactaatttt ttagatactg cccatttaca tgcaaattta aaaattagca
    15061 taaaatactt taaaacttcc ccatgttttt ctaaattcct gcagggcttt tcttatcaaa
    15121 aacttagaaa ttttaattta actctaaaat ctccgtaaga gcataaggga aatttgctat
    15181 cattcaaaaa tgatagatct ggcaaggcca gacattccaa gggttttaag ttattttaaa
    15241 gtgatatcat acaaagctgt agtgtcacac ttttgtgaca ctacatacag catttgtcac
    15301 aaaaataaga cagcactttt ttacagaaaa acaataaaaa aagacatcag ttatcactaa
    15361 tgtcttaaat aataattttg cttttcgaaa ttccaaattg cggtaattga atgtgctttt
    15421 tttcttcgtc tgtcgtttta tcttcatcac ttgtattaat caaattacca tcttcggcat
    15481 cgtctaagtt taaaatttta tgcttttgtt taagcaatcc accataactt aacatacgtt
    15541 ttcgatacaa acctttttct aaatcactta caatttcttg atttttttcg tcgtcatcag
    15601 ttaaaaagtc agatgattta acggaatatt ttgatgtctc ttcgagtgtt ataaaatcat
    15661 ttgaattatt gattaaagat attatattgt ttcatgtttt tacggcgcat ataaagggca
    15721 tgtgtttctt caagttcagt tagaattgtt tgcattaaat aagcttgcat tgacttgatt
    15781 gtttcctttt ggcctttaac tcccctatca tgtatagctt ttttaagtct ttttaaagaa
    15841 gttaatattt catcctcaat gtcctctaac atgtaatgca tatcttcatg ccttgaatta
    15901 aatgattttt ttgctttaag aataacagcc tttatgattt ctaaatctct ataatcatat
    15961 tttaataaat aattagttag ttgttctggg aattcttgca atagcatttc tttatcatca
    16021 aaattatgtg taaattgatt tgaatgattt gaatgattac taatttcatt tttgtacttt
    16081 atatcattca agtcattcat atcattattc tcagtatcat taaagtcaat gtcattaaag
    16141 tcagtatcat tagtgttcga ttttcgaact tctggacgtt cgattttcga acttctggac
    16201 gttcgatttt cgaacttctg gacgttcgat tttcgaactt ccttctcgcc gtaaggttca
    16261 acatcgtttt cttctttttc tattttgtaa atatcacgtt ctgtgacaat aggtttcatt
    16321 aaatatagaa tatttggttt atttaaacca cgtcgttttt gaatgagtag accatcgttt
    16381 tctaaccctt tttttatttt tgttaacttt tcttttttac aatttaagat ttccattagc
    16441 ttttcatttg aataaacaaa gtaaatgtta ccatcttcat caacccagct atttttaata
    16501 gataaattta agcgatcacg taagatagca taggctattt tcatatcatt agttagattt
    16561 ttataatttt cactggtaaa gaatacttta gggatttgat aaaatctttc tttgtaattt
    16621 tcttgcactg taaaatattg attttgcatg acaaaaaacc tctttccata ttttagtttg
    16681 gtaagaggta ataaaacgtt tttatttagc tttacattta tttaatgatt taggtgcttg
    16741 cactaagata ttattcatta tataatacaa gtatcgaaaa ttatataaat aaacagtttc
    16801 taaacgtttt attaccaaac cccgactatt accagtagtt ggggtttttg ttatattaag
    16861 tttattatag cactttaaat aaacttataa aagggaaaat atagctttat caagggttta
    16921 taaacccttg ataaatatca taaacctttc ataaaccctt gataaaaagg ttgatggatg
    16981 tttattttta tttattaatc actttattat taagcattat aagcttataa tattttatca
    17041 agggtttata aacattttat aaagggttga tgatatgaaa agtgtgaaaa agttgagtga
    17101 agaattaggg gttagtaagc aaacgatttt taataatatt aagcgattga atatagagac
    17161 aataaaacag gaaaacactt cgtttattaa agaagatacc gatatagaaa aaatcattca
    17221 aagagtaaat gaaaataaaa agaaatatgg ttttgaaagt actactgaag acaaacaaaa
    17281 aaaagggtcg gataatatta attttgaatc gaaaagcgat gctcaaatag tagaaatcct
    17341 taaaaatcag attgatactt taaataatca aattgaaaaa caagaaagtc gtcatgaaac
    17401 aacaattgaa ttttacagaa aagagttgca agaaagatca aaattgcttg aaaatcagca
    17461 agttctggca ttagagagta ataaaaagat tcaaaaatta gaaaatcaat tagaaaaaga
    17521 aaaacacctt aattatccct ttgatacatc tactaacact agacaaaacg ttgatgcaca
    17581 agaaaaaaca tatactacta atcctgtaaa tattaacaga gatcaggaag aaactaaaga
    17641 aacagagatt caatataagg atatatctgg aagtcaaagc gacgaaagta cacaaggtga
    17701 agaagcaaaa aaagaagacg ttccagctaa tctaaatgac aatgatagtg atatagaaga
    17761 aaagagtgaa gaaacggaac ctaaaaaggg gttttggagt cgtttgtttg gtagctaaaa
    17821 taattgatta ggcactaaaa gttataaaat tttagtgtct tttatatagt gagaacttct
    17881 ggtaatcatc gattatgtaa actaaagtat ttcaaataat taactgtatt aatactctca
    17941 tcatgattgc gttataaacg ttcgttattg agacaaaatt taatagtact actacacaaa
    18001 aagagagtgc gaattcgcac tctctttttg tgataaatga atggttaaga aaataattca
    18061 tccacagttg tatcaaacaa tcttgccaac ttaaatgcta atgtcaatgt aggatcatat
    18121 ttattgtttt ctattgcatt aatagtttgc ctagacactt ttaattcttt acttaaagtt
    18181 tcttgagaaa ttcctttttg ttttctatat tctctaattc tatttttcat taatttaacc
    18241 tttagatgta tattttttat ttgtagtata gtaattaaac agcataagaa atagtgctac
    18301 aattataaag aaaatttctg gatattgaga aaaccaagat ccttcaatac ttggtgacaa
    18361 acctgtaaat ttaagcacta gtgtaaataa catacaatat acaatccaaa taaaactttt
    18421 agccagtatt tcaataaaca ttttacgttg tctttcatcg tatcgatctt gttgtccttt
    18481 tttatctaat gtttctgaag gtaaatattt gttagttata gccgtccata aacaagaaaa
    18541 aattaaaata ataataaaag gaattaaatt cattataaca cctcataaat gtaaaaagta
    18601 tttgacattt atgagtgtaa atatttttga tacaaatgtc aaatactttt tacattataa
    18661 tatattttaa aacaccttat tagtaaaaca attactatat agaaagctgc gaactcgtac
    18721 tcttttttct tgtataatta ttaaaatctc aattcaataa tatgttatgg aatttgagac
    18781 actgtgagag acgctcattt gcattgacaa tcaatttatc aagataatcc cttatcatgt
    18841 ttaattctat aaactgtttg tcttgtgata ttaacttctt tcgcaatctt actaatcgct
    18901 ttgccttctt ctaacatttc caccacgcga tgataaataa cacgtttctg tgggtcttta
    18961 gcatttggtg aataaagtaa agggcgccct ttatatacgc ctttttcctt cgcaacttga
    19021 atcccttgcg cttgtcgacg tttactttca tttctctctt gttctgaaac cattgctaat
    19081 atttgaatga ttaaatcttt cataaactta tccagtaatg gattgccaat tacttcattc
    19141 atcataggta agctggtaat cattaactga acgtcttttt cttttaaata attcacagtt
    19201 tcaataattt catcatagtt acgtcctaaa cgatcaatag attccacaac gaatcgatct
    19261 cccattctga caaaattgag tgcttcttga aatacaggtc tattttccac tgactttccc
    19321 gactgtttct ctgtaaagat tttctccaca ccaaacgtct ttaaattatc caattgtctt
    19381 tctaaatttt gatctatcga tgatactctc gcataaccta taatcattca tcttcactcc
    19441 ataataaata tacaccctaa tcatacgttt taattgttat aatttcaaca attctttttg
    19501 tatggttagg gtgtactcaa agtgtacata tctataatta aaacttacta aaaataaata
    19561 tagatttttt ctttgtaaca gaaccgttca tttgaaggtc atctctatca taaatattta
    19621 aattaactaa aaattttaat catctgttta atacttatga aatgtattta cggtaggtat
    19681 taaaattgat gaaatttata taagtgcttt caatgaaaat gaccgtttat ttatcctcct
    19741 gatttaagga gttagaaatt tcgaaaacga ttctttccat ttgttgcatt tgttccatgt
    19801 ccagatattt aatacattat agaaaaccaa agaccatcac taattaaacg cagttttaaa
    19861 atttcatcag gattgccttc gtctttaaaa tgggcctctt ttaatataag ttctactctt
    19921 tcatacctaa ctctttcaat gccatcgttt catacgccga ttctcctgat tccatagcaa
    19981 actcagcgat aaacattggg aatactgcat tgagttctat tatatgctct ttcattcgtg
    20041 gccatatttc acctccagct ttaccgtatg ctgttataag ttgctctaat ccttcgtcgt
    20101 cgaatacacg atggtgtcct ataaagtcca ttgatgggtc ggagtgggtt gcttcagtcc
    20161 agtctatgag acctgtgacg tttgcttggt tatctaccat tatatgtcct ggatgtaagt
    20221 ccccatgtat catggtcgca tgtcgaggcc atagttcgtc gttttctaac cattgtttcc
    20281 atctgttcca taattcatct gatacgccat aagtttcttt aactttattc attcttcttt
    20341 gaaagtcatt ttttatttct tgtatggttt tgatatttat atgctgaacg ttaatgtttt
    20401 cttctggtat gttgtgtaaa tctacgagtg tttcagctaa tgtgttaata aagttttctg
    20461 gtaatggttt gtgttcaatt tcccatacat aattttgtat ttctggatct attgtggctg
    20521 cgggtttacc tgtaagtttt gggtaagcaa taaggtcttt tgcatgtact ttccacttcg
    20581 gtatttcaaa tgaaacattc ttctgtaaga agtctaccgt ttgtttttcg ggttttgttc
    20641 gtttataaac gtcaggtctt cttggtagtc tcaaaaccca ttctactcca tgtttatctt
    20701 ttccaaatgc aacttgaaaa tcaagtcccg attcattcaa tgagattgtt tgaggttgga
    20761 tgtgtaattg atatttttct gcacatttaa taatttcatt atgtcgagtc attttattgg
    20821 atccttattt ctattatatt tttcttgtga acgtattttt tatattgata taaatgaacc
    20881 taatattcaa tataaattag tgtatagttt ttaagttata tcatgaagag attgtcctgt
    20941 taattcccat tttttatctg atacatgttt aacaaacctt gtatcatgtg atgtaaacaa
    21001 aatgattcca ggatatttat tcataaacat ttctaatgct tctaatgttt taatatctaa
    21061 aaaattagtt ggttcatcca aaattaacat attcgctttc gttgaaaata atactgctaa
    21121 cgataatttc gttctttccc caccactcaa aacattacaa gaacgatcaa gtgcttcatt
    21181 taaacccaag ttatttaaaa tagctctact gaatgattct gatgaatccg tttcatccat
    21241 taaatattgc aataatgaaa cgtcacgcat gtcttcataa gcaagttgac gatagtatgc
    21301 catttgcact ttaggagaac aatcaattcc ctctatttgg tggtaaatag cttcaagtaa
    21361 agttgtctta cctacaccat ttgcacctac gagcgctata tttttgccat atggtatttg
    21421 gaatcgtact tgtgttagca gtttttgact tcctttaacc aatgttagat tttgtgcaat
    21481 gattggataa ttattatgga tatcataaat tttattttgt gggaaattga attcatgata
    21541 actttgtggt ttttcaactt cttccaaatg ttccattctt ttttcaatat gcttagcttg
    21601 tttttgagca gccttctcaa ccgtgccttt ttgttttgat gcacttaaac gatctggtgc
    21661 tatacttttg tttttttgtt ttgatgatgc ttgtgccatt tgttgcgctt gatttcgttt
    21721 agctttactg gcttgggaca atctttgttt ttcacttata tactgttcat attgacgttg
    21781 ttgttctaac tgttcttgtt catattgatt ttgatactgt gtgtaattac ctttaaacac
    21841 tcttattgtg ccatcttctt gtatatccca aattgtgtca gcaatttggt ctataagtgc
    21901 tctatcatga cttactataa ttaaagtacc atagtaatat tttaaaatat ttttcagata
    21961 atctttacca attttatcca agtgatttgt aggttcatct aaaagtaata tcggactata
    22021 atttgatatg acattagcta atttatattt tgctttttca ccaccactca tactgtcggt
    22081 tgtatgcata ggtatatgga gttcactcat taaactaccg tctaacgtgt taaaatcatt
    22141 ttccacatcc atgttaagct gttcaaaata ttgaatttcg ccaaccgttt caactgttcc
    22201 agattctggt tttgtttttt gagcaatcat atttagtaat gtggttttgc cagtaccatt
    22261 acccccaata agtgctattt ttcaaattgg taagcgtaaa gatgaccgat gttaagtgat
    22321 cgtaaatctg tcaatttatg attgatttgg ttaaatttaa ttgtatattg ttccatattt
    22381 atacactcct tgtatattta aaggacgtgt acgcaaaaaa atgagacagg ctactcccgt
    22441 ctcattcaca ttacactttc aaacacttaa aaatttatta tgatgtttta gtatttgaaa
    22501 gcgtttatta ttcctatcga aggataaaaa atgacataag tcatcctatg agtgtgtatt
    22561 gcggacaagc ctttttgaat taatttagtt ttgtattcaa aaaggtttat ttgagtctca
    22621 tagaagctgt cattttaatc ctccttcatc gataaaatag taatgttaat ataacatttt
    22681 gttggttttt ttacaatata tctctaagta gaaagattat ataacaaaag tataaaaata
    22741 caattttaga ttgattatac atctccttaa tttagagtgt actcataaaa tacggttctg
    22801 ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt
    22861 cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact atctaagata
    22921 tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca
    22981 ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa
    23041 aaagcataaa aaagcttatt acaaatggcg tattgatgag acgtatatca aaataaaagg
    23101 aaaatggagc tatttatatc gtgccattga tacagaggga catacattag atatttggtt
    23161 gcgtaagcaa cgagataatc attcagcata tgcgtttatc aaacgtctca ttaaacaatt
    23221 tggtaagcct caaaaggtag ttacagatca ggcaccttca acgaaggcag caatggctaa
    23281 aataattaaa gcttttaaac ttaaacctga ctgtcattgt acatcgaaat atctgaataa
    23341 cctcattgag caagatcacc gtcatattaa agtaagaaag acaagatatc aaagtatcaa
    23401 tacggcaaag aatactttaa aaggtattga atgtatttac gctctatata aaaagaaccg
    23461 taggtctctt cagatctacg gattttcccc atgccacgaa attagcatca tgctagcaag
    23521 ttaaacgaac actgacatga tatattagtg attagctata ttttttactt tgcaacagaa
    23581 ccagccattt aatatgactg ttacaattac taagattcaa gcactattac gccgcacgta
    23641 tgatttcacc actcaagtta ataatttaac agtagatgat tgcgagttac tacttgatgc
    23701 agcaaagctt aaatttaatg aagaaaccat agacctgaca cacactgaat tgcaaatcat
    23761 gcatagctta ttccagaaca agggcaaatt cgtcagtcgt aatgcgttaa tcgaaaaatg
    23821 ctgggaatca gaacacttca ttgatgacaa tacgcttgct gtcaacatta cacgtttacg
    23881 caaaaagcta caaaaactag gacttacaga ttttatcgaa acgaagaaaa atgtcggata
    23941 tcgtgtaggt gacgtatgaa tttcttgaaa tcaatccaac gtgaaattta tattgtcatc
    24001 cttacttgtg ctttattcta ctttatatta ttcatgtata atgtgccgat gcaagcatat
    24061 atgattggtc taggtattgt attgtttgtt tcaatgattt actggggtat ccattacatg
    24121 aactttaaaa aagaataaac actacaggaa cagaacgaag atttaagaat cgaaaaccat
    24181 aaacttcgta atgactttat taactaccaa agtgagttag agtcatattt tttaatgtgg
    24241 gtgcatcaaa tcaagacacc gattacagca tcaaagttac tgcttgaaga tcctgatgaa
    24301 cacgtgattt ctaacgtgcg taatgaagtc ttacaaattg ataattacac gaatcttgca
    24361 ctgaactatt tgaaactcat gaaccaaaag acatacatgg tctttatgga agtgagtgta
    24421 gatgaattaa ttcgaccact gattaaacgt tatgcgatac agtttattca tcatcaaaca
    24481 aagttgcatt atgagaaaag tgaagcggtt atattaacag atgccaaatg ggcatcaatt
    24541 atgattgagc aaatattaaa caatgcatta aaatatgcac gtggcaaaga tgtgtggatt
    24601 acgtttgacg aaaatacaaa gaaattatca atccgagata acggtatcgg cattaatgcg
    24661 agtgatttac cgaaaatctt tgataaaggt ttctcgggct ataacggtag aataagtgag
    24721 aaatcaagcg gtattggttt atatattgtc agcacaatct caaagcgctt aggccataaa
    24781 gtaagtgcta catctacatt aaacgatggt tcaatattca ccattcaatt taaataactc
    24841 caatctttca tttttgtaag attagcggct gtttttgtaa gaatagataa aggcagcctt
    24901 ttctaatcgc gcgtaagata aaggtaacaa caaactaaga aaggtgccag aggtgaaaaa
    24961 tttgaataat ataattgaaa taaataactt aacaaagcaa tatggaagtc agatagcagt
    25021 taataatttg agtataactg ttgaaagtgg acaaatttat ggttttttag gaagaaatgg
    25081 tgcaggcaaa acaactacta taagaatgct tttaggctta attaaaccta cgaaaggtaa
    25141 tattaaaata tttgaaaaag agttcgaaag taataaaact gaaattttaa aaaatattgg
    25201 tgctatggtt gaaacgccag gtttttatag taatttgaca gctaaagaga acttaactat
    25261 aaatgctaaa atattaggta tacaaaaaga aaatgcaatt gaagaagtgt tagaaatagt
    25321 aggactagct tctgaaaaag taaaattgtt taaaaattat tctttaggta tgaagcaacg
    25381 tttagggatt gcgagagctt tattgcacaa tcccgaatta ttgatacttg atgagccgac
    25441 gaatggatta gatcctattg gcataaaaga aattagaaag ttgattaagg atctggctca
    25501 atctagaaat ataaccattt taatttcaag tcatatattg tcagaaatag agcagttagt
    25561 agacaaggtg ggtattattc ataacggagt tttgttagaa gaaattatgt atgaagattt
    25621 aaaaaaaaaa gaacagacaa tttataagta tatcagtatc agatgaagaa aaagttgcat
    25681 gtttgttgga aactaacttc ggaatttatg actataaaat taaagaaaat ggcgaattta
    25741 aaatttattc acatattgat agacaacaag aaattaatag attattagta ttaaacaata
    25801 ttgatgtttt ccagatgaga gtgatagaag ataatctaga aacttatttc gaagacttag
    25861 taggaggtgg cacaattgga taatctactc cgtacagaat ttattaagtt aaaaagatca
    25921 tatatgtttc taataagtat tttaggtaca tgcgtagcac cttttatggt ggttgtagct
    25981 tcttttatta gtatgcggac gaaagtaccg actcctaata ttgtatttaa acagttattt
    26041 gaagaagtca gtttatatca tatgctaatt attggacctc ctctatatgg ggttataata
    26101 gcctatttgt ttggaagaga atatatagaa gatactttaa aaaacttatt aattatacct
    26161 atatctagag aaagtttttt agtaagtaaa ataatattat tattcttgtg gattcaaaca
    26221 ctatctgtta ttgcatggtt gctaacttta atgctaggta tgctattgca ttttcaaggg
    26281 ttaagccaga gtttaataat tgattcattc tttacatttg ttattggcgg agtgttatta
    26341 tggatattat ctccaccaat aattattttg tcgatatatt ttaaaaatta tgttcccaca
    26401 attgttttaa ccataataat tactttgata aatttaatga ctgctaattc tgaacataga
    26461 ggattatttc cttgggctgc agttggagac atatctagag gaacattacc taatacttat
    26521 ccatttctat tatctttaat tatcataatt gttacatcta tattcagtgt aattatatta
    26581 ttctcatact ttaaaaaaac tgatataagt taaaaggagg agaaaaatgg gttttataga
    26641 gcagattaaa gcatttattt taggtgtagt tgaagggttg acagaatttg ctccagtatc
    26701 atcaacaggt catatgatta ttgttgatga tatgtggtta aacactgctg acgatttagg
    26761 aagtgcgtct gcaactactt ttaaggtggt aatacagtta ggaggttctg ttgcaaagtt
    26821 gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt cagatataaa
    26881 caatttaaca aggatgttat cactgtagcc gttggctact atctaagata tgcattgagc
    26941 tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca ttcaacgatc
    27001 taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa aaagcataaa
    27061 aaagcttat
//
