LOCUS       CP143340                5466 bp    DNA     circular BCT 01-FEB-2024
DEFINITION  Enterobacter hormaechei strain 2023CB-00606 plasmid unnamed1,
            complete sequence.
ACCESSION   CP143340
VERSION     CP143340.1
DBLINK      BioProject: PRJNA288601
            BioSample: SAMN38182633
KEYWORDS    .
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Hergert,J., Casey,R., Wagner,J., Young,E.L. and Oakeson,K.F.
  TITLE     Pathogen: clinical or host-associated sample
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5466)
  AUTHORS   Hergert,J., Casey,R., Wagner,J., Young,E.L. and Oakeson,K.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2024) Utah Public Health Laboratory, Utah Public
            Health Laboratory Infectious Disease submission group, 4431 S 2700
            W, Salt Lake City, UT 84129, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 01/25/2024 15:42:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,254
            CDSs (total)                      :: 5,134
            Genes (coding)                    :: 4,987
            CDSs (with protein)               :: 4,987
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 52 of 147
            Pseudo Genes (incomplete)         :: 102 of 147
            Pseudo Genes (internal stop)      :: 13 of 147
            Pseudo Genes (multiple problems)  :: 19 of 147
            Pseudo Genes (short protein)      :: 1 of 147
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="2023CB-00606"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA"
                     /collection_date="2023"
     gene            1..909
                     /locus_tag="V1238_26245"
     CDS             1..909
                     /locus_tag="V1238_26245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016156638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0016491 - oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="WVJ13376.1"
                     /translation="MAGLNKEKKTINKTNSARFPAPPFQQQQQPFPGLAGKMQPRPDHG
                     EDSYQGSGRLNGRKVLITGGDSGIGRAVAIAYAREGADVAINYLPEEEDDAREVVDLIK
                     KAGRNVLAIPGDIRDEAFCGHLVTQAVKGLGGLDILVNNAGRQQFCESIEELTTEDFDA
                     TFKTNVYAMFWITKAAIPHLSPDSVIINTSSVQAYEPSEILLDYAQTKAAIVAFTKSLA
                     KQLAPKGIRVNAVAPGPYWTVLQCCGGQPQEKVEKFGANAPLGRPGQPVEIAPLYVTLA
                     ARENSYTSGQVWCSDGGTGTL"
                     /name="SDR family oxidoreductase"
     gene            complement(1001..1645)
                     /locus_tag="V1238_26250"
     CDS             complement(1001..1645)
                     /locus_tag="V1238_26250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrB6"
                     /protein_id="WVJ13379.1"
                     /translation="MALALVGEKIDRNRFTGEKIENSTFFNCDFSGADLSGTEFIGCQF
                     YDRESQKGCNFSRAMLKDAIFKSCDLSMADFRNASALGIEIRHCRAQGADFRGASFMNM
                     ITTRTWFCSAYITNTNLSYANFSKVVLEKCELWENRWMGAQVLGATFSGSDLSGGEFST
                     FDWRAANFTHCDLTNSELGDLDIRGVDLQGVKLDNYQASLLMERLGIAVIG"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrB6"
     gene            complement(1740..1850)
                     /locus_tag="V1238_26255"
                     /pseudo=""
     CDS             complement(1740..1850)
                     /locus_tag="V1238_26255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015702897.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            1876..2223
                     /locus_tag="V1238_26260"
     CDS             1876..2223
                     /locus_tag="V1238_26260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WVJ13377.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            2217..3056
                     /gene="sul1"
                     /locus_tag="V1238_26265"
     ARG             2218..3053
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3461..5002
                     /locus_tag="V1238_26270"
     CDS             3461..5002
                     /locus_tag="V1238_26270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISCR1 family transposase"
                     /protein_id="WVJ13375.1"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASLE
                     AQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGARRM
                     AESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIKKAG
                     YTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYDELNT
                     LAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGPQQGRK
                     VFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPAVSEKRL
                     ALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVFAPNSKHR
                     VQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVCEHCGGHVK
                     VIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQSRLFD"
                     /name="IS91-like element ISCR1 family transposase"
     ARG             1877..2220
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1005..1645)
                     /name="qnrB6"
                     /gene="qnrB6"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrB6"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1002..1681)
                     /name="QnrB6"
                     /gene="QnrB6"
                     /gene_name="quinolone resistance protein (qnr)"
                     /tool="rgi"
                     /drug_class="fluoroquinolone antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 atggctggct taaacaagga aaaaaagacc atcaataaaa ccaattctgc gcgttttccg
       61 gcgccgcctt ttcaacagca gcagcagccc tttcccgggc tggcggggaa aatgcaaccg
      121 cgccccgatc atggagaaga cagctatcag ggaagcggtc gcctgaatgg gcgcaaggta
      181 ttaattaccg gtggggattc agggattggt cgtgctgttg ctattgccta tgctcgtgaa
      241 ggcgctgatg ttgcgattaa ctatttacct gaagaagaag acgatgcgcg tgaagtggtc
      301 gatctgataa aaaaagcagg cagaaatgtt ttggccatcc ccggcgatat ccgtgatgag
      361 gctttttgcg gtcatctggt aacacaggcg gtaaaaggac tgggagggtt ggatatcctc
      421 gtcaataatg cgggtcgtca gcaattttgt gagtcaattg aggaactcac cacagaagac
      481 ttcgacgcaa cattcaaaac caatgtttac gctatgtttt ggatcaccaa agcggccata
      541 ccccatcttt caccagacag cgtgataatt aatacctcct ccgtacaggc ttatgagcca
      601 agtgaaatct tgcttgatta tgctcagact aaagcagcta tcgtggcatt tactaaatcg
      661 ctggcgaaac agctggcccc gaaagggatc cgtgtcaatg ccgtcgcgcc gggtccatac
      721 tggactgtac tgcagtgctg tggtggtcaa ccgcaggaaa aggtggagaa atttggggca
      781 aatgcgccgc tgggacgccc tggtcaaccg gtggaaatcg cgccgcttta tgtcaccctg
      841 gccgctcggg agaacagcta tacgtctggt caggtctggt gttctgatgg ggggaccgga
      901 accctctaac gtttacgctc tgtgcgtcga aagtgacttt taaggcaagg gcggacacta
      961 ttgtataagg gcgggagcgg tacttaccgc tccgtgaatg ctaaccaatc accgcgatgc
     1021 caagccgctc catgagcaac gacgcctggt agttgtccag cttaacgcct tgtaaatcaa
     1081 cgccccgaat atctaagtca cccaactccg aattggtcag atcgcaatgt gtgaagttcg
     1141 ctgctcgcca gtcgaaagtc gaaaactcgc cgccggagag atctgaacca ctgaacgtcg
     1201 cgcccagtac ctgggcaccc atccaacggt tttcccacag ctcacacttt tccaacacga
     1261 ctttcgaaaa attggcgtag cttagattgg tattcgtgat atatgcgcta caaaaccagg
     1321 tgcgcgtggt gatcatattc ataaagcttg cgccgcggaa atctgcgcct tgtgcgcggc
     1381 agtggcgaat ttcaatgccc agcgcactgg cattgcgaaa atccgccatg gataaatcac
     1441 agcttttaaa aatggcatct ttcagcatcg cacgactaaa attgcaccct ttctggcttt
     1501 cacgatcata gaactgacag ccgataaatt cagtgccgct caggtcggca cctgaaaaat
     1561 cacagttaaa aaatgtacta ttttcaattt tctcaccggt gaaacggttt ctgtcaattt
     1621 tttcgccaac gagtgccaga gccatatttg tacctgtttt tttatacagt aatggcgtca
     1681 tggtaaaccc tgatggggtt atgcgtcaaa tccgccaata tgacatctgc aaatgtgcgt
     1741 taaatctggt gttttttcag caaagcgcga agctgatggt aagtcagccc cagtaattca
     1801 gcggcttttt tctggttaaa ttttgcctgc tgtaagccgt gcataataag ccctacacaa
     1861 attgggagat atatcatgaa aggctggctt tttcttgtta tcgcaatagt tggcgaagta
     1921 atcgcaacat ccgcattaaa atctagcgag ggctttacta agcttgcccc ttccgccgtt
     1981 gtcataatcg gttatggcat cgcattttat tttctttctc tggttctgaa atccatccct
     2041 gtcggtgttg cttatgcagt ctggtcggga ctcggcgtcg tcataattac agccattgcc
     2101 tggttgcttc atgggcaaaa gcttgatgcg tggggctttg taggtatggg gctcataatt
     2161 gctgcctttt tgctcgcccg atccccatcg tggaagtcgc tgcggaggcc gacgccatgg
     2221 tgacggtgtt cggcattctg aatctcaccg aggactcctt cttcgatgag agccggcggc
     2281 tagaccccgc cggcgctgtc accgcggcga tcgaaatgct gcgagtcgga tcagacgtcg
     2341 tggatgtcgg accggccgcc agccatccgg acgcgaggcc tgtatcgccg gccgatgaga
     2401 tcagacgtat tgcgccgctc ttagacgccc tgtccgatca gatgcaccgt gtttcaatcg
     2461 acagcttcca accggaaacc cagcgctatg cgctcaagcg cggcgtgggc tacctgaacg
     2521 atatccaagg atttcctgac cctgcgctct atcccgatat tgctgaggcg gactgcaggc
     2581 tggtggttat gcactcagcg cagcgggatg gcatcgccac ccgcaccggt caccttcgac
     2641 ccgaagacgc gctcgacgag attgtgcggt tcttcgaggc gcgggtttcc gccttgcgac
     2701 ggagcggggt cgctgccgac cggctcatcc tcgatccggg gatgggattt ttcttgagcc
     2761 ccgcaccgga aacatcgctg cacgtgctgt cgaaccttca aaagctgaag tcggcgttgg
     2821 ggcttccgct attggtctcg gtgtcgcgga aatccttctt gggcgccacc gttggccttc
     2881 ctgtaaagga tctgggtcca gcgagccttg cggcggaact tcacgcgatc ggcaatggcg
     2941 ctgactacgt ccgcacccac gcgcctggag atctgcgaag cgcaatcacc ttctcggaaa
     3001 ccctcgcgaa atttcgcagt cgcgacgcca gagaccgagg gttagatcat gcctagcatt
     3061 caccttccgg ccgcccgcta aatatctcct tttgggttgt taataaaaca tccaataagt
     3121 tgactgtgcg tgaaaaagaa agttttgtgt gatggcgttg aagatcgcac cgttaagctc
     3181 ttatgtggga tggtgcagag ctcgacgact accgataaaa cgcaaccgcc gcaaacagac
     3241 aagaaaaagc cccaactgat aacagttggg gcttcagtat tgtgattggt ggagcaatag
     3301 caccctgaac ccaaaacctt ctcgctcaac cggtagtggc tgataacaac tcgtgagggc
     3361 tattgcgggt taagcattta gcgatgtcta gggccagact ggacgtctga acgcaagccg
     3421 ctgatactgt acataaccac agtatcagcg gaggataccc atgtcgctgg caaggaacgc
     3481 cacggcgagt caatcgccca ctcaaacaaa cggttacgaa cgccaccaac ccgaccagac
     3541 gctgctctac cagctggttg agcagcacta cccagccttc aaagcctcac tcgaagccca
     3601 aggtcaacac ctgcctcgct acatccaaca agaattcaac gacctcctcc aatgtggccg
     3661 tctggagtat ggtttcatgc gggttcgctg cgaggattgt catcacgagc gtctggtcgc
     3721 cttcagctgt aaacgacgcg gcttttgccc tagctgcggt gcccgccgga tggccgagag
     3781 tgcggcgctg ctgatagacg aagtcttccc caaggagccc attcgccagt gggtgctcag
     3841 ctttcctttc cagctacgct ttttgctggc tcgccatccc cagctgatgg gccaggtctt
     3901 gagtatcgtc tatcgtacac tctcaactca tctgatcaaa aaagccggtt acaccaaagc
     3961 ctctgcacaa actggctcag tgactcttat ccaacgcttt ggctccgcgc taaatctcaa
     4021 tgtccactac cacatgctgt ttctcgatgg tgtctatgcc gaagatgact atggcaagca
     4081 acgcttccat cgtgtcaagg cacccactta cgatgagctg aatacgctcg ctcacaccct
     4141 cagccatcgc atcgctcgct gcatggaaaa gcgtgggatt ttggagcgtg atgccgagaa
     4201 tacgtggttg acactggaag agggcgaaga cgatacgctg actcaattac atggtgcttc
     4261 ggttacgtat cgcattgccg tcggccccca gcaagggcgc aaagtcttca ccctgcaaac
     4321 cttgccaggg cgtgaggata aagccgactc aagcagtcga gtagccaacc atgctggttt
     4381 ctcgctacac gccggtgtga tggccgaagc gcatcagcgg gataagcttg agcgcttgtg
     4441 tcgctacatt agtcggccag cggtttcaga aaaacgtctg gcattaaccg ccaatgggca
     4501 ggtgcgttac gagctcaaaa ctccgtaccg caatggcacc acccatgtga tcttcgagcc
     4561 gctggacttc atcgccaaac tcgctgcgtt ggtacctaag ccgcgagtca acctcacacg
     4621 cttccacggc gtctttgcac cgaacagcaa acaccgagtt caagtaacac ccgccaagcg
     4681 gggcaagaag cccgacaaat cggaaggtct cgatactaac tggcgtgaca agagtcctgc
     4741 agagcgccac cgcgccatga cctggatgca acgcctcaag cgagtcttca atattgatat
     4801 tgaagtctgc gaacactgcg gcggtcacgt caaagtgatt gccagcatcg aagatccgaa
     4861 ggtcattgag cagattctca agcatctgaa acagaaaaca gccaaggcga atgccgccaa
     4921 gcagcgtgag ctgccaccag aacgagcgcc gccactgact cccagcctgt tcgatccatc
     4981 acagagtcgt ctctttgact gacgacccca aatccaacac tgctcaacac tgccaacttt
     5041 taaacggggc ggtggggcag tttgtatctc tcgagctatc aggctagaga ttttaccgcc
     5101 aaatcgaacc ttattagagc ggtttaggct ggaccggcag ttaaaattgg ggcttgagcg
     5161 gtaaacgagt gagggaattt caggtaagat acttcggatg aggagcaaaa aggtggttta
     5221 tacttcctat accccagatt gagatgttaa gtgtggttgc tatttattaa cactgcgaac
     5281 tggataagtc tcaaataata ttttttaaat taaatctaac gttggtgggg atataagcgc
     5341 aacggtagag gaaagtaggg agggtaatat tccgagaaaa ttaagtgtag ctggataata
     5401 taggtcatac cattcatttt ggtctacgat tattagtctt tgtgataaat aatgagaggt
     5461 aattga
//
