LOCUS       CP141426               20766 bp    DNA     circular BCT 10-JAN-2024
DEFINITION  Staphylococcus aureus strain Sau106 plasmid unnamed1, complete
            sequence.
ACCESSION   CP141426
VERSION     CP141426.1
DBLINK      BioProject: PRJNA1046723
            BioSample: SAMN38508047
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20766)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Nyerere,A., Musila,L. and
            Revathi,G.
  TITLE     Displacement of hospital-acquired methicillin-resistant
            Staphylococcus aureus clones by heterogenous community strains in
            Kenya over a 13-year period
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20766)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Musila,L. and Rivathi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2023) Pathology, Aga Khan University, Nairobi, 3rd
            Parklands Avenue, Nairobi, Nairobi 00100, Kenya
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 21-MAR-2023
            Assembly Method                   :: FLYE v. 2.9.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/06/2023 16:24:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,876
            CDSs (total)                      :: 2,793
            Genes (coding)                    :: 1,769
            CDSs (with protein)               :: 1,769
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 1,024
            CDSs (without protein)            :: 1,024
            Pseudo Genes (ambiguous residues) :: 0 of 1,024
            Pseudo Genes (frameshifted)       :: 980 of 1,024
            Pseudo Genes (incomplete)         :: 52 of 1,024
            Pseudo Genes (internal stop)      :: 31 of 1,024
            Pseudo Genes (multiple problems)  :: 35 of 1,024
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            NCBI analysis of this genome has determined that >30% of the
            predicted CDS features contain frameshifts, which is well above the
            usually observed value of <10%.
FEATURES             Location/Qualifiers
     source          1..20766
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Sau106"
                     /isolation_source="clinical"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya: Nyeri"
                     /lat_lon="0.4371 S 36.9580 E"
                     /collection_date="2020"
                     /collected_by="Aga Khan University Hospital, Nairobi"
                     /note="genotype: MRSA"
     gene            join(20584..20766,1..42)
                     /locus_tag="UM707_14255"
     CDS             join(20584..20766,1..42)
                     /locus_tag="UM707_14255"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WRN06458.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESWNFLTQVVKANGK"
                     /name="DUF4062 domain-containing protein"
     gene            join(20766,1..752)
                     /locus_tag="UM707_14260"
     CDS             join(20766,1..752)
                     /locus_tag="UM707_14260"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WRN06459.1"
                     /translation="MELFNSSSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYT
                     EMEYNFAKSLGKPIYVFEMNKASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSK
                     VSQTLMQSVPSEIKENSGWIRVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYV
                     KTFYFQHTPFDDSYIEDIENYLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGK
                     KPLAQAGHFKLSFYEEDLKLLQKIIRLR"
                     /name="DUF4062 domain-containing protein"
     gene            complement(976..1791)
                     /locus_tag="UM707_14265"
     CDS             complement(976..1791)
                     /locus_tag="UM707_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WRN06460.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(1784..3225)
                     /locus_tag="UM707_14270"
                     /pseudo=""
     CDS             complement(1784..3225)
                     /locus_tag="UM707_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(3197..3789)
                     /locus_tag="UM707_14275"
                     /pseudo=""
     CDS             complement(3197..3789)
                     /locus_tag="UM707_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(4053..4433)
                     /gene="blaI"
                     /locus_tag="UM707_14280"
     ARG             complement(4057..4433)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(4423..5193)
                     /locus_tag="UM707_14285"
     CDS             complement(4423..5193)
                     /locus_tag="UM707_14285"
                     /inference="COORDINATES: protein motif:HMM:NF013100.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class D beta-lactamase"
                     /protein_id="WRN06462.1"
                     /translation="MGQSLTDYNYKKPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYY
                     IYNEKESRKRYSPDSTYKIYLALFGLDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTA
                     MQNSVNWYFERISNQIPKNYTAAQLKQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFK
                     NMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDK
                     YYFATHLSDGNPSGKNAELISEKILKGMGVLNGQ"
                     /name="class D beta-lactamase"
     gene            complement(5468..6217)
                     /locus_tag="UM707_14290"
                     /pseudo=""
     CDS             complement(5468..6217)
                     /locus_tag="UM707_14290"
                     /inference="COORDINATES: protein motif:HMM:NF017390.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /name="M56 family metallopeptidase"
     gene            6282..7123
                     /gene="blaZ"
                     /locus_tag="UM707_14295"
                     /pseudo=""
     CDS             6282..7123
                     /gene="blaZ"
                     /locus_tag="UM707_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     gene            7492..8100
                     /locus_tag="UM707_14300"
     CDS             7492..8100
                     /locus_tag="UM707_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRN06465.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            8512..8805
                     /locus_tag="UM707_14305"
     CDS             8512..8805
                     /locus_tag="UM707_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WRN06463.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            8880..10814
                     /locus_tag="UM707_14310"
     CDS             8880..10814
                     /locus_tag="UM707_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WRN06464.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            10818..11027
                     /locus_tag="UM707_14315"
     CDS             10818..11027
                     /locus_tag="UM707_14315"
                     /inference="COORDINATES: protein motif:HMM:TIGR01655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WRN06452.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKRVINWIF"
                     /name="YxeA family protein"
     gene            11140..11764
                     /locus_tag="UM707_14320"
                     /pseudo=""
     CDS             11140..11764
                     /locus_tag="UM707_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]; GO_process: GO:0006810
                     - transport [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="putative bacteriocin export ABC transporter"
                     /name="putative bacteriocin export ABC transporter"
     gene            12001..12929
                     /gene="mobV"
                     /locus_tag="UM707_14325"
                     /pseudo=""
     CDS             12001..12929
                     /gene="mobV"
                     /locus_tag="UM707_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010889940.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            12930..13268
                     /locus_tag="UM707_14330"
     CDS             12930..13268
                     /locus_tag="UM707_14330"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WRN06467.1"
                     /translation="MTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKELNYTLKLFNQ
                     VFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQAQEREIIFKE
                     DREDGYTL"
                     /name="recombinase"
     gene            13649..14508
                     /locus_tag="UM707_14335"
                     /pseudo=""
     CDS             13649..14508
                     /locus_tag="UM707_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]; GO_process: GO:0006270 - DNA
                     replication initiation [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            14595..14936
                     /locus_tag="UM707_14340"
     CDS             14595..14936
                     /locus_tag="UM707_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WRN06453.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(15175..15246)
                     /locus_tag="UM707_14345"
     CDS             complement(15175..15246)
                     /locus_tag="UM707_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRN06466.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            15395..15580
                     /locus_tag="UM707_14350"
     CDS             15395..15580
                     /locus_tag="UM707_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRN06454.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(15799..16541)
                     /locus_tag="UM707_14355"
                     /pseudo=""
     CDS             complement(15799..16541)
                     /locus_tag="UM707_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /name="DUF536 domain-containing protein"
     gene            16951..17627
                     /locus_tag="UM707_14360"
                     /pseudo=""
     CDS             16951..17627
                     /locus_tag="UM707_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            17638..17920
                     /locus_tag="UM707_14365"
                     /pseudo=""
     CDS             17638..17920
                     /locus_tag="UM707_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            19128..19745
                     /gene="cadD"
                     /locus_tag="UM707_14370"
     ARG             19129..19742
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            19764..20111
                     /locus_tag="UM707_14375"
     CDS             19764..20111
                     /locus_tag="UM707_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WRN06456.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            20280..20372
                     /locus_tag="UM707_14380"
     CDS             20280..20372
                     /locus_tag="UM707_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRN06457.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     ARG             6882..7123
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.5"
                     /coverage="28.47"
     BGC             3512..13805
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          17976..18123
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          13650..14508
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(15800..16541)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12002..12276
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 tggaactttt taactcaagt agtaaaagcc aatgggaaat aataacacaa tggatcaatg
       61 aatcagatgc agtgatatta ttgttaggtt ctagttatgg aacaattgat agtgaagaaa
      121 atattagcta tacagaaatg gagtacaatt ttgctaaatc tttaggtaaa cctatatatg
      181 tttttgagat gaataaagca tctaccgaat ccgcggaaaa gtctaaaaaa ttagatgagt
      241 ttaagacaaa agttaaagaa aatagactaa ttagtccaaa tattaatgat atttcggaat
      301 taaaaagtaa agtatctcag actttaatgc aaagtgtacc tagtgaaatt aaagaaaata
      361 gtggatggat aagagtacag gattgtggta aaaatgtaaa aaaattaaaa aaattggatg
      421 ctatacaaag agatttagat acatatgatt ttttgaaaga agaactttat aaaatattca
      481 tgtatgtaaa aactttttat ttccagcaca caccatttga tgatagttat attgaagata
      541 tagaaaacta cctgctaaat tatgaaaata atccacataa atcattcatg aaaataaaag
      601 tttatgatta taaaaacttt ttaaaacatt taaaaaacat attgatttta attaaacaag
      661 gaaaaaagcc attagctcaa gccggtcatt ttaaattaag cttttacgaa gaggatttaa
      721 aattgttaca aaaaattata agactacgct agtcgatatt aaaggattga ataaacattt
      781 ttataaggaa tgtgataggt gcttaaaagc atataatatt tttattgagg gtataaataa
      841 acatttatat gaatgatata agtacaccct aatcatacat atataattgt tgtcacttta
      901 ctcgatatat gagaatgact ttacctaata aatgagaaaa gcaacgcact atattaaaat
      961 gcgttgcttt ttctattatc gaatacctat aactaaacta tctctagctg tttctacaac
     1021 ttctgtactt attttatcta aaccatttat atccataatt ctgtctatct gcgcaaataa
     1081 acgatgaatc agcctaaaat tcccttttgt aattttaata atcgtcgtta ttgcctcata
     1141 atcagtaaag tcttcgagtt ttaaatcaaa tcctaagtct tgccacttat attctaatat
     1201 atgatgcgtc tcatctttac ttagattatc aaattcatgc gcaaaaccta tacgcgaata
     1261 tagttgagga taacgagata gttttttctc tatacccggc ataccaataa atatcattgc
     1321 taaattatgt tcatcataaa tagctcttaa ttgctctaaa tgttgcactt taaggcgatc
     1381 aatctcatct actataatta aatcaatata tttaaacata tcactataat gtttactatg
     1441 ttcatgtcca tacttattta caacatgtaa tttttgaccc aaatcaatga ttgcagtaat
     1501 actatataaa tcattcctta atttagtttg tttttctgct ggtgcattat aaaatatttt
     1561 atccaccgat agtatgtcat cggtcgtttt actagctaaa tcttcccaac ctctatggtt
     1621 aacttgtttt tcaatagtat cccaatttgt gtaataccta gacgataaag tttttccgac
     1681 accaggttga ccataacata taccaatata ctgatattta atacaagcat cacaaaattc
     1741 agcaaagcgt ttatactctt tcgtttcaat gaaattttga tttttagtca ttacgatatc
     1801 tctttaattt tttgacgttt ttagtcgttt cttgaggtga ataaccacaa ttttttcttc
     1861 cttaattaat tccgtggtac ttggactagc aatattttgt tttaagtgtt ttcttctctg
     1921 actacgagcg tgctgtatgt cttttatatc tatggagtaa tcagctattt ctggacatat
     1981 agcagtacaa agaaattcat ctctataaaa cacacgtatt tcagccatat catttgggtt
     2041 ataacgaatc agtacatatt cacctacata agcttctaga ttagtattac tgtatcgaaa
     2101 accttgaaaa tgaatgccat ctgaatgaac ttttctagat ttaggtattt ccaacaataa
     2161 taaatcaagt tgttctaagc tacttggcat attagggaaa aagtgattac tattccaatg
     2221 actgataggc gtggtatgaa tagtactatg ttctttttga ttataatctt caattaaaaa
     2281 gtaacgtaat ttttcttcaa aattgtgaaa atttattaga ttactaggag tatcattatt
     2341 gtttatatat ccaggcagtt gttctaagaa agtttgatta actgtctgaa agaatcgttc
     2401 tatttttcca cgaccacgag gaacaccaac tttcgaaaac atcaagttaa ttttcaaatc
     2461 aatagcgact tgttccatat gatgtgaagt aaagtcactt ccatgatctg tgtagaattt
     2521 ttcgggtata ccacacactg gccaattggt atcattttta ttccatattg cttggtgtag
     2581 tgttaatgct gtgttttgag cattgggggc atcaaaactt aagaaatagc ctgcaattgc
     2641 acgactatag tcatccataa taatagttag ccatggtcta ttgatattac ctttttggtc
     2701 taatataaag atatctagca aagtatggtc tgcttgccat atttcattgg gtctcgagga
     2761 ttctctaatt tgtattaaat cgtacttatt ttgatagtat ttttcaccct gatgagagaa
     2821 atcaataaca gacttaggca tcgctttaat aacactataa atttgtttat aacttggtat
     2881 atcaaaatta ttttctttac agtaattagt gattttccta tgaattgtgg ctatactatt
     2941 tcttttattc ataagcgcaa ggcgttcaat ttcatcaatt atctttggtt ctattttacg
     3001 tgttccttta tcagctcttg tcgcatagat tagtccttta agtccttgtt ctttatatga
     3061 cttattccac ctataaaggg tgcttaacgc aatcccttta cttttagaaa tacttgataa
     3121 agattgttcg cctaggataa aaggttttat aatattgtac ttttgagtag cttttttacg
     3181 tttagcttca gaaaaattag ttagatactt ctccttgttt ttcatcttcc ttgtcctcca
     3241 atttattgag gtaacgataa attgttgtac gtgaaacatg ccactgttct gcaattgtct
     3301 taattggcgt gccattatca taaagggtct taagtaagtt taaatctttt tgatttaatt
     3361 tttctggtct gcctccatat cggcctctag cacgtgctgc aattcggcca gctgaagaac
     3421 gctctaaaat taaattacgt tcaaattctg caaatgctgc gaataaatga aataataatt
     3481 gtccagttga acttgattta tccattgtta tattttcttc taaactatgg aaacttacac
     3541 ctcgttcgtt aagctcatta actaatgtga ttaaatcctc catattacgt cccaatctat
     3601 ctaatctcca aacaacaatc gtatctcctg acctcgcaaa ttcaattgct ttatctaaac
     3661 caggtctttt acttttgaac cactcatatg gtcattaaat atcttttcac aaccatatgt
     3721 atttaatcga tcctcctgta aatttaaatt ttgtaatcca gttgaaactc ttgcataacc
     3781 tattttcaaa atacaaacct cctatataca tcttcagtgt accataactt aattacaagg
     3841 tcttttatga acatagattt tttgttgggt ttttgaacac ataatcctat gtaattctta
     3901 cttatttaga cataaaagaa gagtgtacag aaaatggtta ttttctgtac actctcatct
     3961 ttaataatat attttaaatg tcattaacaa aactaattta ataagagtca agcatagttt
     4021 acatatgtat tatgtttgaa acatacctct aattactttt tactaatatc atttaaaata
     4081 tctcgcaatt cttcaatttc tttgttattt aattcttcat ttttcgcaaa attcaacact
     4141 aaacttttca tatcccctcc atacagttta ttaagaaagg ttttagcagt tttcatttta
     4201 atatcgtctt ctttaatatt tgatgagtaa aaataaatat tttctgattt gtatcgtttt
     4261 ataatctctt ttttatatag tcttgtgatt aatgttctaa tcgttttatc actaacttct
     4321 ttatattttt gaatttcaac tacaatttca ttagctgata ctgatttttt atcccatatt
     4381 atattcataa catcccattc agccatagat atttcaactt gcttattggc catttaaaac
     4441 acccattcct tttaatattt tttcacttat taattcagca tttttcccag acgggtttcc
     4501 atctgataaa tgtgtagcaa aataatactt atcatgattt gtaattacgt aacctacaaa
     4561 ccacccatta ttatacttcc cgtttactat acctgtacct gttttcccat acagttcata
     4621 cttttcattt ttcttaatca ataatgaaga agataattga ttctttgctt ttttactaaa
     4681 atggttattt tgttccatca tatttttaaa aactattact tgttcaagat tagatatttt
     4741 caaactatct tccatccaat agcttttata acttcccaaa ttttcattac cataatttaa
     4801 ttgcttgagt tgagccgcag tatagttctt tggtatttga ttactaatac gttcgaagta
     4861 ccaattaact gaattttgca ttgctgtatt taaatcttgt tccttattcc aagactcgaa
     4921 aagataatgt ttatgattcc atgacatacg tgaattttta tcacttataa tatgacggtc
     4981 aagtccaaac agtgctaaat aaattttgta agttgaatca ggagaatatc tttttctact
     5041 ttctttttca ttataaatat agtatttgtc tttcttcatg ctgtacataa cgaaagatcc
     5101 actatttgaa ccaaaatttt tactttcatc taaaatttgg taatcgcttt gtaagggctt
     5161 tttataatta taatcagtta aggattgccc cattaaaaac tggctttgaa ttatcatgat
     5221 aaaaaagtaa aaatacaaat aaaaattaga attaattttg actgcttttt cagatcggct
     5281 tcttttatat taattaatct atttttgagt aatgattttt taccattaaa tgaatggctt
     5341 aatatatttt tgttgaaaaa tgaggttttt aatacggagt ccataataga ttccgcataa
     5401 gttttaaatt catttttgtt aatattatta aggacaaatc tatcggcttc tacttcattg
     5461 tcatgaatta tctttctttt acaatatgta ctaatggatt gtaactcata ataatagaga
     5521 agatattaaa gataattaaa tgtaaagtat ctctattttt agcatgagca tattcatgca
     5581 gtattatata ttttagtctt ttatcaatta cacttttaaa atatgaacta ggaatcaaaa
     5641 taatatattt cccataccaa aaagttattg gagattgaat agcctctgct tttcgaatca
     5701 caatattttt tatattgatg gttgaaaagt atcgtatcta ttttattttt tcattttcgt
     5761 ttagataaag tgactgtttc tttaaatatt taagatataa taaggctttc aaaaatttaa
     5821 aacttaaaat aataactaaa actatccaaa taactgtgca gatattatca attgaatccc
     5881 aattaaactt atggatatct gttgcgaact cttgaacagg tttggtggta attatgttat
     5941 ggttcaagtc gtgtgactta ctttcaactg tgggcgcttg attattcaca ttattaaatt
     6001 ttataaaaga gaatttaatt gggataaaag gaattaatcc agcaagcaca gttagatacc
     6061 aaactttata atttaaacta taattaaaat agcgttttaa tatgtaccta aaaaatacta
     6121 acaatagaaa tataaaacaa aagcttacta cactcattat tagtaattta gccattttga
     6181 caccttcttt caaatattta taataaacaa ttgacatcaa tattacaatt gtaatattat
     6241 tgttttgtaa aaattacaac tgtaatatcg gagggtttat tttgaaaaag ttaatatttt
     6301 taattgtaat ggctttagtt ttaagtgcat gtaattcaaa caattcacat gccaaagagt
     6361 taaatgattt agaaaaaata taatgctcat attggtgttt atgctttaga tactaaaagt
     6421 ggtaaggaag taaaatttaa ttcagataag agatttgcct atgcttcgac ttcaaaagcg
     6481 ataaatagtg ctattttgtt agaacaagta ccttataata agttaaataa aaagtacata
     6541 ttaacaaaga tgatatagtt gcttattctc ctattttaga aaaatatgta ggaaaagaca
     6601 tcactttaaa agaacttatt gaggcttcaa tgacatatag tgataataca gcaaacaata
     6661 aaattataaa agaaatcggt ggaatcaaaa aagttaaaca acgtctaaaa gaactaggag
     6721 ataaagtaac aaatccagtt agatatgaga tagaattaaa ttactattcg ccaaagagca
     6781 aaaaagatac ttcaacgcct gctgctttcg gcaagacttt aaataaactt atcgcaaatg
     6841 gaaaattaag caaaaaaata aaaatttctt acttgattta atgtttaata ataaaaacgg
     6901 agacacttta attaaagatg gtgttccaaa agactataag gttgctgata aaagtggtca
     6961 agcaataaca tatgcttcta gaaatgatgt tgcttttgtt tatcctaagg gccaatctga
     7021 acctattgtt ttagtcattt ttacgaataa agacaataaa agtgataagc caaatgataa
     7081 gttgataagt gaaaccgcca agagtgtaat gaaggaattt taatattcta aatgcataat
     7141 aaatactgat aacatcttat agtttgtatt atattttcta ttatcgttga catgtataat
     7201 tttgatatca aaacctgatt ttccctttat tattttcgag atttattttc ttaattctct
     7261 ttaacaaact agaaatattg tatatacaaa aaatcataaa taatagatga atagtttaat
     7321 tataggtgtt catcaatcga aaaagcaacg tatcttattt aaagtgcgtt gcttttttct
     7381 catttataag gttaaataat tctcatatat caagcaaagt gacataattg ttgaatttat
     7441 agtaactgaa acgtatgatt agggtgtata ttaattatga gatggaaatc aatgattgtt
     7501 ggctatgcga gagtatcatc gaacgatcaa aatttagaaa gacaacttga aaatttaaag
     7561 acgttttgtg ctgaaaaaat atttacagaa aaacagtctg ggaaatctat tgaaaataga
     7621 ccagtacttc aagaagcact taactttttg aggatgggag atcggtttgt agtagaatcc
     7681 attgattgtt taggtcgtaa ttatgatgaa gtgattcata ccgttaatta tttaaaagac
     7741 aaagaagtac aattaatgat tactagctta cctatgatga atgaagtggt tggcaatcca
     7801 ttactggata agtttatgaa agatttaatt attcaaatat tagcaatggt ttcagaacaa
     7861 gagagaaatg aaagtaaacg tcgacaagcg caaggaattc aagttgcgaa ggaaaaaggc
     7921 gtatataaag ggcgcccctt actttattca ccaaatgcta aagatccaca gaaacgtatt
     7981 atttatcatc gcgttgtaga aatgttagaa gaaggccaat caattagtaa aattgcgaaa
     8041 gaagtaaata taacaaggca gacgatttac agaattaaaa acgataatga tttgatttaa
     8101 taaactttgt ttcaatgcaa ctgagagctt ctcacagcgt ctcaaaacag atgattataa
     8161 tctattatga gtttttaata ataagacaag aaaagagagc gtaaatatgc tctctctttc
     8221 tcattaacga atgtttataa cgcaatcatg atgagagtat taatacagtt aattatttga
     8281 aatactttag tttatataat gttgaattat aggtagtgaa attgtattta ttatacattg
     8341 tcatatcgtt gtttaatgat agttaattta aggataatag aattaatatt atatatagat
     8401 gaacaaaaca agcaacagag cagaaaaaac acttttagat tatttttact cattctctat
     8461 tttatttatt tttgctataa taaataaaga atattaaatg taggtgtttt tatgaaaaag
     8521 aaatttgttt ctagttgtat tgctagtaca atcttattcg gcactttatt aggtgtaact
     8581 tataaagctg aagctgcaac agtacatgta gctggtggtg tttggagcca tggtattgga
     8641 aaacattacg tatggtctta ttatagtcac aataaaagaa atcatggttc aacagcagta
     8701 gggaaatatt catcttttag tggtgttgct cgacctggtg ttcaatctaa ggcatctgct
     8761 ccaaaggctt ggggtggaaa caaaacattt tatagtcttc actaattaca tatattaatt
     8821 aaggagaata gacagaatta agtaaactta attctgtcta ttctcttgaa agaggcaata
     8881 tgaaaaaatt caaattattt ttagatttta gtactttatt attaatttca gggctattat
     8941 ttttattttt cttcaaagaa aatgaagaaa ttatacctga aagttccaat attttaacaa
     9001 tctctaattg ggataaatct aacagtaaat caaaagtgtt agatgtcatt gaatcaggcg
     9061 ccaaaaatca aaatatacaa ataattaaat ccgttaaaga ttttgataat aaaaaagaat
     9121 tttttgtttt caactcaaaa cgaaataatt ctgactttat acgtaataaa acatcacttt
     9181 taactccatc agatttatta aacagagaga taaaaggaaa gtattatatt attggtgaac
     9241 atttcaatgt agaagagctt acgagtgaat taaaaaaagc tggtttaaca tctgaagttg
     9301 aatacataaa tagaaacata ttattttttg aattagtcat agataatgat ttattagtgc
     9361 ctttcatatt cttaggcgta ttatatcttt tgtacttctt atatgacaga ggatataatt
     9421 tgaaatttta tgctattcaa aagctacatg gcttttcaac tacacgcatt atttttcata
     9481 atattcatat aaaaatcatt tattggctag tacttaccgc tattttcttt attgctaata
     9541 tattaatcat tcatatagcc aatttagaat tggatttctt aatgtttatt cgtagattta
     9601 tcgtgttgct ttttgttttt gcttgtatta ctacattgct gtggctgatt tcgtatagtc
     9661 ttcttttgaa gttaagtatt ccattaatct taaaagggaa aaaaggatat aagttttcaa
     9721 tatttatggg taccttcacc aaatgtatca tggtgctaat actatctttt ttactggcac
     9781 aaaatttaaa tgcttatacg aagttaaaga atatatatga ctctgaaaaa atctggcaaa
     9841 agttagataa ttactataca ttagagattt ctcctaatat tagaaattca gaagaaaaac
     9901 aaattttaga aactaatata tacaatttaa ttaagaaaag cgaacaactt ggtggattgc
     9961 ttttaaagaa taataatata gccaatcccg ataaaaacaa ttacattcct gaaaatggca
    10021 atgtcttttt tatcaataac aattttctga atttctataa aaatataaat catgatttta
    10081 aaatgattga caatcattcg gataaaataa acgtgtttat tcctccaagg ttacaatatc
    10141 aaaaatctga aattcaaaaa aatcaccaag gatggattga ctttcaaaag caacaaaaca
    10201 aaaaagtaga tgtgcaagta ctgtcaaaaa acgtatctgt tttttctttt gatcgcacaa
    10261 ctaatttgaa atttgggtat ctagattctc caatagtaat gttgttgaca cttgacgatt
    10321 taacaggaga tttttattta gctgctgttt ctcaaggtgg atatctattt aaagatttag
    10381 atacacttaa acagttgctt aaagataatc acctagaaga agaaattagc ggtataacta
    10441 attacaagga ttctgtgtta aatgaattaa atgaaacgaa aacaaaaatg ataataacaa
    10501 tagttactat tattattaac gttttcattc ttttgatagc tactgtattt gaaacaattc
    10561 aatattttag ctggaataaa aagcaactat tattaagaaa aattcatggt tattcattat
    10621 tcagcagtaa tgtacgttat ttaacaattt ctatcttact ttctattatg ttagcttaca
    10681 ctacgcatat tttatttggt tcaaagatat tactattcat aataatgtct attgctatta
    10741 ttcaacattt acttcaaatt gcttatatta aatatcttga aaaatacttt aaagatttaa
    10801 tgagggagat ttaaacaatg aaaagaactt taattattgt aacaattgta ctattaatca
    10861 tcatacttag tctgttattg gttagaaatg agcatttaga tcgttttaac ccactgttaa
    10921 aagaaaaagt atcttatgcc aaagttccaa aagataccca ggactataga aatataactg
    10981 tatactctaa aaatggagaa aaaagagtta taaattggat tttttaggtt atgatcctac
    11041 aaaagaatat gtgaaagtaa atcataaagg gaaatatgtg cgttcgatag aatacattac
    11101 aaaagatatt cctagctttt taaaatgagg tgaccgatag tgataaaact tgaaaatgtt
    11161 tttgtaaaaa aggtaataaa aacattttag acggatgtaa ctttaatttt gaaaaaggaa
    11221 aatcatatgc tttagttgga gaaagtggcg ctggaaaatc tactttactt aacataatcg
    11281 ctgggttcga agatgtatca caaggaagca tatatattga agataagtta ctaaaaaaga
    11341 aagtcgattt ttatagatat acgttagggt atttgtttca aaattttgct ttacttgaaa
    11401 atcaaacaat cagtcaaaat ttagatttag ccctaaagtt caaaaagaat aaaaaagata
    11461 atatgaactt aaagaaagaa gtattaaaaa ggtcggccta gatttagata tcaagagaat
    11521 tgttagttct ctaagcggtg gtgaacaaca aagagtagca ttggcaagat taatattaaa
    11581 agatccgaaa atcattttag ctgatgaacc tactgggtca ctagatacga aaaatggaaa
    11641 aatagttatt gatttattat tgaagctact tgatgaaaat aaaactatga ttgtcgtaac
    11701 gcatgattta gagcttgcga aacgatttga tgtcatagtc aatatttctg agcttagaag
    11761 ttaagaaata ttgataggta tagccataca tagagaaaaa acaatatgaa atatgattag
    11821 tcattacttt tgagttttta atttaaggac tggattttcc agtccttttt tatgatgaca
    11881 aaaaacaagc ctcgcagagc acacgttttt aatgacttat ttggttttta ataagtctag
    11941 tatgttaaaa cttttctgtg tttaggtgtt ataatcatat gcagtggaag ttgatttatt
    12001 atgtcttatt caattattcg agttgttaaa gtgaaatcaa aaacaaatac aagaggtatt
    12061 caaagacata ttcaaagaga aaataaaaat tatgaaaata tagatattga tttaagtaag
    12121 tcatatttaa actatgattt agtcaatgat actaagtttg attttaataa aaaaattgat
    12181 gagaaaatcg aaaaaaatta taaagggaaa cgcaaaatta gaacagatgc cattaaacat
    12241 attgatggat taattacatc agataatgtg ttttttaatc aattatctga agaagagaca
    12301 aaatagtttt ttaagcatgc taaagcgttc ttggaagaag aatacggtaa agaaaatctt
    12361 ttatatgcga cagtacatat ggatgagata acaccacata tgcattatgg cgtagttcct
    12421 attactaaag atggacgttt aagtgcgaaa gaagttgtag gtaataaaaa agcattaacc
    12481 gaattccaag atagattcaa tacgtatatt aataagcaag gctatgattt aaaacgagga
    12541 atttctagac aacttacaaa agaaaaacat gatcaagtta gccgttataa acaaaaaaca
    12601 gaatatcata aacaaatgca tatgcgctag aagcaaatag aggattattt aaagcaagaa
    12661 aatgataaat tgatacaaaa ctaccaaaaa tcattagata cgcttaaaaa gcttctgagt
    12721 gtcatgtatg aaattaaaac taaaaatgta ggtggatggt ttcataaaga gaagcaagaa
    12781 acaggcaata ttgtaattac taaaactgat tttgaaaaat acactaaaca aattaaagca
    12841 gcacagatga tattagatga ttatgaatgt attaaaagtg ggaagtcatt aaaaaagcag
    12901 agaaacaaaa tgaaagttta gttaatgaat tgactagtgt ccatatggaa aatgaaaagc
    12961 tggttgaaga atttaatgat ttagcacaac gttataatta tttgttgtca gagaatgaaa
    13021 agaaagataa agaactaaat tatacgctta agttattcaa tcaagttttt aaaatcatta
    13081 aaagtatgat gaaagaagag cgttatcata cactaataaa tcatattgat aatcatttag
    13141 acaattctaa aatacgtgaa gtaatgacga tagataacaa tgatgaacag ttctttaaga
    13201 agaaatatca agcacaagaa cgagaaatca tttttaaaga agatagagaa gatggttata
    13261 cattataaaa atagatattt aaatgcattt gtttgaggtt aattattttt aggatgaaaa
    13321 ataggtagcc ccctcgaact ttttaatata tttttataaa tcttttaaaa acctttttag
    13381 gggcttgtta atccctagag caacaaggga tttcaatgcc taaaggagtg tttttgccac
    13441 ataaaaggag tgtttttgcc acataaaagg agtgtttttg ccacataaaa ggagtgtttt
    13501 tgccacataa aaggagtgtt ttaaaaagtt gtactccttt tatggtttga cattgataat
    13561 aaagtagttt attgtgaata aaagttttca aatgggagtg tatattcaaa cgatactcct
    13621 ttaggttcgt aataaagggg gctgtatcat gacaggagag acagttgtat ataaaaatga
    13681 aatgaattta gttccattaa ggcgatttac agctactgaa attaatttat tttttgcgat
    13741 gtgtaataaa ttaaaagagc aagatactaa tacattacgt ttgtcttttg atgaattaaa
    13801 aaaattaagt aattatagtc cagaaacacg taatattaat agatttgcta atgatttaga
    13861 taatgtgtat aaaaagatgt tgaatttaac cattagatat gaagatgatg atgtaataga
    13921 aagattcgtt ttattcaatc attatagaat ccataagcga gaacaatatc tagaaatatc
    13981 aacttcttca aatttaaaac acatattgaa ttcaattact aataatttta caaaatttga
    14041 attaaaagaa atgactaggc ttaaatctac atattctaaa aatatgttta gattacttaa
    14101 acaatacaaa catacaggct atttaaaaat tcacatcgat gattttaaaa atcgtttaga
    14161 tatacctaaa tcttatcgta tgactgatat taacaaaaat gtttttaaac ctattattat
    14221 tgaattaggt tctatattta ataatcttac tatcaataaa atcaaagcga aaaaagggcg
    14281 taaaattgaa tggatagagt tcacatttga cgctgagaaa cgcattcata acaaacgaca
    14341 acctcaaatg tccaagatag ataaatcaag acaatatgtg aggcgtgaaa agacgcctaa
    14401 atggttagaa gaacggtcat atgaaaagca acctcaaaaa gattacgacc cacaattaga
    14461 gaaagaacga gaggattttt aaaacaactt gaactgaatt gggaataacg caacttttcg
    14521 ttgcgagttg gttaactaaa agtatcgtga cttttcaatt attttaatta tagtttgagt
    14581 taaggagtga ttttatgaaa ttagctgaag ctataaaaga acagagagaa ttaaaaggat
    14641 ggtctcaaga ggaattagcc aatatattaa aggtttccag acaaagtgtt tctaaatggg
    14701 aaagtgccaa aaactatcct tccttagata ttttgattgc tatgagcgat ttattcggaa
    14761 tctctttaga gcatttaatt aaaggagatg cacgttttaa aaaagttatt ttagagggaa
    14821 attatagaga gagtaacagg gtaccttcca tagttgattt tctttatgat ttttggtggc
    14881 ttttctttcc tgttgccgga tttttagttt gggccattca ttcgttcatg ggttgatttt
    14941 aaaatcaaaa tttaatgcac atcaggcaat atgaaaaagg aaagtatttt tacgacacct
    15001 tgaaatgtat tgataagaat agaagagttt acaaaaggca atatgaaata tatactaaaa
    15061 gtaacaagaa tttcgtttgt aaacgcacaa aaccccgaac tattcgccgt agttcggggt
    15121 tttttggtga attggcttta atcgtctata ttatttttta tcacgtttat ggagctaata
    15181 accaaataac gtaacgagac aaccactgat tgccgttgtc atgatgtgaa caagaatttc
    15241 attcataaat cgcacctcct ctctacgccg aattgacatc tgagagatag acgaccttca
    15301 cattataaca aatctctcct tccatgaaat aacatgaata ttaataaatg ttgttatata
    15361 ttaaagataa ataaatataa gggtgggatt gataatgttt ggcgatcaaa gacaagaagc
    15421 tacaaaatat gtcattaaag aaggttatca agatatttat ttcctcaaca aaaacgggga
    15481 atggtattat ttcgaagtaa gaagtgtctg gcgtggcaaa catattatta gagttaaaga
    15541 tggtttgtta ggttggagaa aagaaatagt aactgaataa agatacaaaa tacttgccaa
    15601 tgcaaaagaa tgaaaacgcg tcaaatcaac gatgtataaa agatgcataa aagataatga
    15661 aagtaaaaag ccataaatgc cgtcatatag gcatttatgg ctttttgttt ggttaacata
    15721 atcgatgatt atcagaagtt caattcacat aaaaaagcac ggctaattta tgaacttgtc
    15781 gtaccttttt aattaaaatt agttaccaaa tagacgactc caaaacccct ttttaggttc
    15841 cgtttcttca ctcttttctt ctatatcact atcattgtca tttggattag ctgaaacgtc
    15901 ttctctttgt gcttcttcac cttgtgtact ttcgtcgctt tgacttccag atatatcctt
    15961 atattgaatc tctgtttctt tagtttcttc ctgatctcgg ttaatattta caggactagt
    16021 agtatatgtt ttttcttgtg catcaacgtt ttgtctagcg ttagtagatg tatcaaaggg
    16081 ataattaagg tgtttttctt tttctaattg attttctaat ttttgaatct ttttattact
    16141 ctctaatgcc agaacttgct gattctcaag caattttgat ctttcttgca actcttttct
    16201 gtaaaattca attgttgttt catgacgact ttcttgtttt tcaatttgat tatttaaagt
    16261 attaatctga tttttaagta tttctactat ttgagcatcg cttttagatt caaaattaat
    16321 attatccgac tctttttttg tttgtcttca gtagcacttt caaaaccata tttcttttta
    16381 ttttcattta ctctttgaat gattttttct atatcggtat cttctttaat aaacgaagtg
    16441 ttttcctgtt ttattgtctc tatattcaat ctcttaatat tattaaaaat cgtttgctta
    16501 ctaaccccta attcttcact caaccttttt acacttttca tatcatcaac cctttataaa
    16561 atgtttataa acccttagta aaatattata agcttataac gattaataat aaagtaatcg
    16621 acaaataaaa atataaattc gccaaccttt ttatcaaggg tttgtaaagg gtttatggtg
    16681 tttatcaaag gtttataaac ctatattttc ccttttaaag tttattcaaa gtgctataat
    16741 aaccttaata taacaaaaac cccaactact ggtaatagtc ggggtttggt aataaaacgt
    16801 ttagaaactg tttatttata taattttcga tacttagatt atataatgaa taatatctta
    16861 gtgcaagcac ctagattatt aaataaacac aaaaaatgta agcgttttat tacctcttac
    16921 caaactaaaa ttcggaaaga ggtttttatt atgtcaatta aactttacaa cataaatgag
    16981 gaatacagag aaaagtttta tcaaataccg aaagtatttt ttacaaatcc taaatatatc
    17041 aagttatcca atgatgcaaa aatggcatgg ggtattctta gagatcgttt agatttatca
    17101 attaaaaatg gttgggttga ttctaaaaca ggtaatattt atttttatta caaaaatgaa
    17161 aacccacaaa atatattaaa ttgtaaaaaa gataaagtaa ttaaaataaa gaaagaactt
    17221 aattgaagcc gaattactac tacaagaaag acaaggttta aataagacaa ataaacttta
    17281 tttagttaaa ccagaagtaa cagaagatga tatttataaa attcaaaagc aagaaaacac
    17341 tgttgagagc agcaatggca aggaagtcgg aaaaaccgac ttcaagaagt cgataaaaca
    17401 gaatctaatg atactgaact tagctatact gaatctaaca atactgaaat aaatgatatg
    17461 aatgacttga atgatataga gtccgaaaat gaaattagta atcattcaag tcaatgcaag
    17521 gttatttaat gcaaacaatt ttaactgaat ttgaagaaac acatgcactt tatatgcgcc
    17581 gtaaaaacat gaaacaatat aatatcttta atcaatcatt caaatgattt tataacaatc
    17641 aaagatacat caaaatattt cgttaaatca tctgactttt taactgatag cgatgaaaaa
    17701 atcaagaaat tgtcagtgat ctagaaaaag atttgtatcg aaaacgtatg ttaagttatg
    17761 gtggattgct taaataaaaa cataaaattt taaacttaga cgatgctgaa gatggcaatt
    17821 taattaatac aagtgatgaa gataaaatag caaatgaaga agaaaaggca cattcgatta
    17881 cggcaatttt gaaaagcaaa attattattt aaggcattag tgataactga tgtctttttt
    17941 attacttttt gtaaaaaaag tgctgtctta tttttgtgac aaatgctgta tgtagtgtca
    18001 caaaagtgtg acacttgagc tttttatgac cccacacaaa aacattttcg aagccttgaa
    18061 atatctggct ttgccagatc ccccattcat tgatggggac aaatttccct tatgctctta
    18121 cggagatttt agagttaaat taaaatttct aagtttttga taagaaaagc cctgcaggaa
    18181 tttagaagaa cgtggggaag ttttaaagaa ttttatgcta atttttaatt tgcatgtaaa
    18241 tgggcagtgt ctaaaaaata gttattgttt ttgctcaaat ttttgttttt gaaaatagca
    18301 tatatttatt tggctcatat ttgcgtttta aaagcgtata taagttttag atataaaact
    18361 atatgaatca cccctaaatc tttaaaatgc cctcttaaaa ttcaaaataa gggcataaaa
    18421 aataaaagcc ccccagataa agtgaggtag ctttttcttt cgacgccgta tcgtcgatgt
    18481 aattcaaaaa agttatgggc tataaatcta catcactttt tcaagaatgt agtagcaata
    18541 ttcaacgcaa attaattttt ataactgctc ggaatatctc aagccgtttc tttaattttg
    18601 aaataaaaaa atcgacgaag gtcgattacg tttttgcaca tgtcgattta tccgacgtat
    18661 aagtgcgccc ttacgggatt taactagatt ataacgacga attttagacc tgtaaagcaa
    18721 taacaattag gtctaccagg tagataaagt gtacaaagta gaaccgaaaa agttatttat
    18781 tttgaagatt tttcgtagat ataatttgct aataaacttc ctaaaactga ataaagaaaa
    18841 atagttaaac tcatgtaatc actccataat tctgaagtgt ctccatgtct acgcatagac
    18901 acgcatttat gccgagaaaa tttattgtgc gttgagaaga acccttaact aaacttgcag
    18961 acgaatgtcg gcatagcgtg agctattaag ccgaccattc gacaagtttt gggattgtta
    19021 agggttccga ggctcaacgt caataaagca attggaataa agcacctatg attatttaaa
    19081 aatataagtt ataatacatt caaaaatatt tttgaatgag gtgtattatg attcaaacgg
    19141 ttgttgctgc tgctgttctt tatattgcta cagcagttga tttattagta attttattaa
    19201 tattttttgc tagagcaaag actagaaaag aatatagaaa tatttatgtt ggtcaatatt
    19261 tagggtctat tattttaata ttagttagtt tgtttttagc ttttgtatta aattatgttc
    19321 cagaaaagtg gatattaggt ttattgggtt taataccaat ttatcttgga attaaagtgg
    19381 ctatttatga tgattgtgaa ggagaaaaga gagctaaaaa agaattgaat gaaaaaggat
    19441 tgtctaaatt agttggtacg gttgcaattg ttacgatagc aagttgtggc gccgataata
    19501 ttggtttatt tgttccgtat tttgtgacat taagtgttac taatttatta cttactctgt
    19561 ttgtcttttt aattttaatt ttcttcttgg tgtttactgc acaaaaatta gctaatatcc
    19621 caggaattgg agaaattgtt gagaaattta gtcgttggat tatggctatc atttatatag
    19681 ctttaggttt atttattatt attgaaaatg acactattca aacaatttta ggatttatat
    19741 tttaatttag ggtgtgattt tatatgagtt atgaaaatac ttgtgatgtg atctgtgtac
    19801 atgaggataa agttaacaat gctttaagtt ttttagaaga tgataaatct aagaaattac
    19861 ttaacatttt agaaaaaatt tgtgatgaga agaaattgaa aatcatatta tctttgatta
    19921 aagaagatga gttgtgtgtt tgtgatattt ctttgatatt gaaaatgagt gttgcttcaa
    19981 cttcacatca tttaaggctt ttatataaaa atgaggtact tgatttttat aaagatggaa
    20041 agatggcata ttattttatt aaagacgatg aaataagaga gtttttctct aaaaatcagg
    20101 agggtttttg aaacgagtga aacgagtttc ttcttgtctt gatactataa aaaacaaagt
    20161 tatataacat aagacgactt atcggaagtt atctatcatc gtatattcgg agatgatata
    20221 atatacaggt cgcctatctc tcaggcgtca attcagacgc agagaggagg tgcattactt
    20281 tgctaatcat tttcgttcac atcatagcac cagtcatcag tggctgtgct gttgcgtatt
    20341 atacttattg gcttagtaaa cgcaacaaat aattaatagg cgactttata agccagcatc
    20401 gaaaaaatcc ccacactatt gcagtagtgt ggggattggt gcattaattg ttaatcattt
    20461 tcgttatcta gattataaca ctggttagta gaggaatgca aaaagataat attttaagta
    20521 gtctttttgg atattatcat atgatatatt tatgtaaatt gattttttat taaaggagca
    20581 tatatgagta atactaaaat taaatatcaa atttttattt catcaactta tttagattta
    20641 atagaagagc gtcaagcagt agtagaagca gttttaaaca gtaataatat tccagcaggt
    20701 atggaacttt ttaactcaag tagtaaaagc caatgggaaa taataacaca atggatcaat
    20761 gaatca
//
