LOCUS       CP141422               20696 bp    DNA     circular BCT 10-JAN-2024
DEFINITION  Staphylococcus aureus strain Sau113 plasmid unnamed1, complete
            sequence.
ACCESSION   CP141422
VERSION     CP141422.1
DBLINK      BioProject: PRJNA1046723
            BioSample: SAMN38508049
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20696)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Nyerere,A., Musila,L. and
            Revathi,G.
  TITLE     Displacement of hospital-acquired methicillin-resistant
            Staphylococcus aureus clones by heterogenous community strains in
            Kenya over a 13-year period
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20696)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Musila,L. and Rivathi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2023) Pathology, Aga Khan University, Nairobi, 3rd
            Parklands Avenue, Nairobi, Nairobi 00100, Kenya
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 21-MAR-2023
            Assembly Method                   :: FLYE v. 2.9.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 17x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/06/2023 16:10:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,882
            CDSs (total)                      :: 2,801
            Genes (coding)                    :: 1,616
            CDSs (with protein)               :: 1,616
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 1,185
            CDSs (without protein)            :: 1,185
            Pseudo Genes (ambiguous residues) :: 0 of 1,185
            Pseudo Genes (frameshifted)       :: 1,142 of 1,185
            Pseudo Genes (incomplete)         :: 56 of 1,185
            Pseudo Genes (internal stop)      :: 48 of 1,185
            Pseudo Genes (multiple problems)  :: 56 of 1,185
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            NCBI analysis of this genome has determined that >30% of the
            predicted CDS features contain frameshifts, which is well above the
            usually observed value of <10%.
FEATURES             Location/Qualifiers
     source          1..20696
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Sau113"
                     /isolation_source="clinical"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya: Kiambu"
                     /lat_lon="1.1748 S 36.8304 E"
                     /collection_date="2022"
                     /collected_by="Aga Khan University Hospital, Nairobi"
                     /note="genotype: MRSA"
     gene            complement(join(20584..20696,1..154))
                     /locus_tag="UM702_14280"
     CDS             complement(join(20584..20696,1..154))
                     /locus_tag="UM702_14280"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRN02824.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKNFCFQLKTK"
                     /name="hypothetical protein"
     gene            complement(229..522)
                     /locus_tag="UM702_14285"
     CDS             complement(229..522)
                     /locus_tag="UM702_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WRN02825.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(934..1542)
                     /locus_tag="UM702_14290"
     CDS             complement(934..1542)
                     /locus_tag="UM702_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRN02832.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(1910..2751)
                     /gene="blaZ"
                     /locus_tag="UM702_14295"
                     /pseudo=""
     CDS             complement(1910..2751)
                     /gene="blaZ"
                     /locus_tag="UM702_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     gene            2858..4611
                     /gene="blaR1"
                     /locus_tag="UM702_14300"
                     /pseudo=""
     CDS             2858..4611
                     /gene="blaR1"
                     /locus_tag="UM702_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /name="blaR1"
     gene            4601..4981
                     /gene="blaI"
                     /locus_tag="UM702_14305"
     ARG             4602..4978
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            5245..5838
                     /locus_tag="UM702_14310"
     CDS             5245..5838
                     /locus_tag="UM702_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRN02827.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            5810..7251
                     /locus_tag="UM702_14315"
                     /pseudo=""
     CDS             5810..7251
                     /locus_tag="UM702_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            7244..8058
                     /locus_tag="UM702_14320"
                     /pseudo=""
     CDS             7244..8058
                     /locus_tag="UM702_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity [Evidence
                     IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            complement(8282..8581)
                     /locus_tag="UM702_14325"
     CDS             complement(8282..8581)
                     /locus_tag="UM702_14325"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRN02828.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKIIRLR"
                     /name="hypothetical protein"
     gene            complement(8626..9150)
                     /locus_tag="UM702_14330"
     CDS             complement(8626..9150)
                     /locus_tag="UM702_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WRN02829.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKN"
                     /name="DUF4062 domain-containing protein"
     gene            complement(9362..9454)
                     /locus_tag="UM702_14335"
     CDS             complement(9362..9454)
                     /locus_tag="UM702_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRN02830.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(9623..9970)
                     /locus_tag="UM702_14340"
     CDS             complement(9623..9970)
                     /locus_tag="UM702_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WRN02831.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(9989..10605)
                     /gene="cadD"
                     /locus_tag="UM702_14345"
                     /pseudo=""
     CDS             complement(9989..10605)
                     /gene="cadD"
                     /locus_tag="UM702_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            complement(11812..12094)
                     /locus_tag="UM702_14350"
                     /pseudo=""
     CDS             complement(11812..12094)
                     /locus_tag="UM702_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(12105..12781)
                     /locus_tag="UM702_14355"
                     /pseudo=""
     CDS             complement(12105..12781)
                     /locus_tag="UM702_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            13191..13933
                     /locus_tag="UM702_14360"
                     /pseudo=""
     CDS             13191..13933
                     /locus_tag="UM702_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /name="DUF536 domain-containing protein"
     gene            complement(14152..14337)
                     /locus_tag="UM702_14365"
     CDS             complement(14152..14337)
                     /locus_tag="UM702_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRN02819.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            14486..14557
                     /locus_tag="UM702_14370"
     CDS             14486..14557
                     /locus_tag="UM702_14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRN02833.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(14796..15137)
                     /locus_tag="UM702_14375"
     CDS             complement(14796..15137)
                     /locus_tag="UM702_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WRN02820.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(15224..16083)
                     /locus_tag="UM702_14380"
                     /pseudo=""
     CDS             complement(15224..16083)
                     /locus_tag="UM702_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]; GO_process: GO:0006270 - DNA
                     replication initiation [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            16140..16430
                     /locus_tag="UM702_14385"
     CDS             16140..16430
                     /locus_tag="UM702_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRN02821.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGLPIFHPKK"
                     /name="hypothetical protein"
     gene            complement(16465..16803)
                     /locus_tag="UM702_14390"
     CDS             complement(16465..16803)
                     /locus_tag="UM702_14390"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WRN02834.1"
                     /translation="MTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKELNYTLKLFNQ
                     VFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQAQEREIIFKE
                     DREDGYTL"
                     /name="recombinase"
     gene            complement(16804..17731)
                     /gene="mobV"
                     /locus_tag="UM702_14395"
                     /pseudo=""
     CDS             complement(16804..17731)
                     /gene="mobV"
                     /locus_tag="UM702_14395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010889940.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(17968..18593)
                     /locus_tag="UM702_14400"
                     /pseudo=""
     CDS             complement(17968..18593)
                     /locus_tag="UM702_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18706..18915)
                     /locus_tag="UM702_14405"
     CDS             complement(18706..18915)
                     /locus_tag="UM702_14405"
                     /inference="COORDINATES: protein motif:HMM:TIGR01655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WRN02822.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKRVINWIF"
                     /name="YxeA family protein"
     gene            complement(18919..20376)
                     /locus_tag="UM702_14410"
     CDS             complement(18919..20376)
                     /locus_tag="UM702_14410"
                     /inference="COORDINATES: protein motif:HMM:TIGR01654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="WRN02823.1"
                     /translation="MPFIFLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHI
                     KIIYWLVLTAIFFIANILIIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLL
                     KLSIPLILKGKKGYKFSIFMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKL
                     DNYYTLEISPNIRNSEEKQILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGN
                     VFFINNNFLNFYKNINHDFKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQN
                     KKVDVQVLSKNVSVFSFDRTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKD
                     LDTLKQLLKDNHLEEEISGITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFE
                     TIQYFSWNKKQLLLRKIHGYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMS
                     IAIIQHLLQIAYIKYLEKYFKDLMREI"
                     /name="DUF1430 domain-containing protein"
     ARG             complement(1911..2152)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.5"
                     /coverage="28.47"
     BGC             1..5522
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(11611..11758)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          13192..13933
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(15225..16083)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttgatttact gttagattta tcccaattag agattgttaa aatattggaa ctttcaggta
       61 taatttcttc attttctttg aagaaaaata aaaataatag ccctgaaatt aataataaag
      121 tactaaaatc taaaaataat ttgaattttt tcatattgcc tctttcaaga gaatagacag
      181 aattaagttt acttaattct gtctattctc cttaattaat atatgtaatt agtgaagact
      241 ataaaatgtt ttgtttccac cccaagcctt tggagcagat gccttagatt gaacaccagg
      301 tcgagcaaca ccactaaaag atgaatattt ccctactgct gttgaaccat gatttctttt
      361 attgtgacta taataagacc atacgtaatg ttttccaata ccatggctcc aaacaccacc
      421 agctacatgt actgttgcag cttcagcttt ataagttaca cctaataaag tgccgaataa
      481 gattgtacta gcaatacaac tagaaacaaa tttctttttc ataaaaacac ctccatttaa
      541 tattctttat ttattatagc aaaaataaat aaaatagaga atgagtaaaa ataatctaaa
      601 agtgtttttt ctgctctgtt gcttgttttg ttcatctata tataatatta attctattat
      661 ccttaaatta actatcatta aacaacgata tgacaatgta taataaatac aatttcacta
      721 cctataattc aacattatat aaactaaagt atttcaaata attaactgta ttaatactct
      781 catcatgatt gcgttataaa cattcgttaa tgagaaagag agagcatatt tacgctctct
      841 tttcttgtct tattattaaa aactcataat agattataat catctgtttt gagacgctgt
      901 gagaagctct cagttgcatt gaaacaaagt ttattaaatc aaatcattat cgtttttaat
      961 tctgtaaatc gtctgccttg ttatatttac ttctttcgca attttactaa ttgattggcc
     1021 ttcttctaac atttctacaa cgcgatgata aataatacgt ttctgtggat ctttagcatt
     1081 tggtgaataa agtaaggggc gccctttata tacgcctttt tccttcgcaa cttgaattcc
     1141 ttgcgcttgt cgacgtttac tttcatttct ctcttgttct gaaaccattg ctaatatttg
     1201 aataattaaa tctttcataa acttatccag taatggattg ccaaccactt cattcatcat
     1261 aggtaagcta gtaatcatta attgtacttc tttgtctttt aaataattaa cggtatgaat
     1321 cacttcatca taattacgac ctaaacaatc aatggattct actacaaacc gatctcccat
     1381 cctcaaaaag ttaagtgctt cttgaagtac tggtctattt tcaatagatt tcccagactg
     1441 tttttctgta aatatttttt cagcacaaaa cgtctttaaa ttttcaagtt gtctttctaa
     1501 attttgatcg ttcgatgata ctctcgcata gccaacaatc attgatttcc atctcataat
     1561 taatatacac cctaatcata cgtttcagtt actataaatt caacaattat gtcactttgc
     1621 ttgatatatg agaattattt aaccttataa atgagaaaaa gcaacgcact ttaaataaga
     1681 tacgttgctt tttcgattga tgaacaccta taattaaact attcatctat tatttatgat
     1741 tttttgtata tacaatattt ctagtttgtt aaagagaatt aagaaaataa atctcgaaaa
     1801 taataaaggg aaaatcaggt tttgatatca aaattataca tgtcaacgat aatagaaaat
     1861 ataatacaaa ctataagatg ttatcagtat ttattatgca tttagaatat taaaattcct
     1921 tcattacact cttggcggtt tcacttatca acttatcatt tggcttatca cttttattgt
     1981 ctttattcgt aaaaatgact aaaacaatag gttcagattg gcccttagga taaacaaaag
     2041 caacatcatt tctagaagca tatgttattg cttgaccact tttatcagca accttatagt
     2101 cttttggaac accatcttta attaaagtgt ctccgttttt attattaaac attaaatcaa
     2161 gtaagaaatt tttatttttt gcttaatttt ccatttgcga taagtttatt taaagtcttg
     2221 ccgaaagcag caggcgttga agtatctttt ttgctctttg gcgaatagta atttaattct
     2281 atctcatatc taactggatt tgttacttta tctcctagtt cttttagacg ttgtttaact
     2341 tttttgattc caccgatttc ttttataatt ttattgtttg ctgtattatc actatatgtc
     2401 attgaagcct caataagttc ttttaaagtg atgtcttttc ctacatattt ttctaaaata
     2461 ggagaataag caactatatc atctttgtta atatgtactt ttttatttaa cttattataa
     2521 ggtacttgtt ctaacaaaat agcactattt atcgcttttg aagtcgaagc ataggcaaat
     2581 ctcttatctg aattaaattt tacttcctta ccacttttag tatctaaagc ataaacacca
     2641 atatgagcat tatatttttt ctaaatcatt taactctttg gcatgtgaac tgtttgaatt
     2701 acatgcactt aaaactaaag ccattacaat taaaaatatt aactttttca aaataaaccc
     2761 tccgatatta caattgtaat ttttacaaaa caataatatt acaattgtaa tattgatgtc
     2821 aattgtttat tataaatatt tgaaagaagg tgtcaaaatg gctaaattac taataatgag
     2881 tgtagtaagc ttttgtttta tatttctatt gttagtattt tttaggtaca tattaaaacg
     2941 ctattttaat tatagtttaa attataaagt ttggtatcta actgtgcttg ctggattaat
     3001 tccttttatc ccaattaaat tctcttttat aaaatttaat aatgtgaata atcaagcgcc
     3061 cacagttgaa agtaagtcac acgacttgaa ccataacata attaccacca aacctgttca
     3121 agagttcgca acagatatcc ataagtttaa ttgggattca attgataata tctgcacagt
     3181 tatttggata gttttagtta ttattttaag ttttaaattt ttgaaagcct tattatatct
     3241 taaatattta aagaaacagt cactttatct aaacgaaaat gaaaaaataa aatagatacg
     3301 atacttttca accatcaata taaaaaaata ttgtgattcg aaaagcagag gctattcaat
     3361 ctccaataac tttttggtat gggaaatata ttattttgat tcctagttca tattttaaaa
     3421 gtgtaattga taaaagacta aaatatataa tactgcatga atatgctcat gctaaaaata
     3481 gagatacttt acatttaatt atctttaata tcttctctat tattatgagt tacaatccat
     3541 tagtacatat tgtaaaaaga aagataattc atgacaatga agtagaagcc gatagatttg
     3601 tccttaataa tattaacaaa aatgaattta aaacttatgc ggaatctatt atggactccg
     3661 tattaaaaac ctcatttttc aacaaaaata tattaagcca ttcatttaat ggtaaaaaat
     3721 cattactcaa aaatagatta attaatataa aagaagccga tctgaaaaag cagtcaaaat
     3781 taattctaat ttttatttgt atttttactt ttttatcatg ataattcaaa gccagttttt
     3841 aatggggcaa tccttaactg attataatta taaaagccct tacaaagcga ttaccaaatt
     3901 ttagatgaaa gtaaaaattt tggttcaaat agtggatctt tcgttatgta cagcatgaag
     3961 aaagacaaat actatattta taatgaaaaa gaaagtagaa aaagatattc tcctgattca
     4021 acttacaaaa tttatttagc actgtttgga cttgaccgtc atattataag tgataaaaat
     4081 tcacgtatgt catggaatca taaacattat cttttcgagt cttggaataa ggaacaagat
     4141 ttaaatacag caatgcaaaa ttcagttaat tggtacttcg aacgtattag taatcaaata
     4201 ccaaagaact atactgcggc tcaactcaag caattaaatt atggtaatga aaatttggga
     4261 agttataaaa gctattggat ggaagatagt ttgaaaatat ctaatcttga acaagtaata
     4321 gtttttaaaa atatgatgga acaaaataac cattttagta aaaaagcaaa gaatcaatta
     4381 tcttcttcat tattgattaa gaaaaatgaa aagtatgaac tgtatgggaa aacaggtaca
     4441 ggtatagtaa acgggaagta taataatggg tggtttgtag gttacgtaat tacaaatcat
     4501 gataagtatt attttgctac acatttatca gatggaaacc cgtctgggaa aaatgctgaa
     4561 ttaataagtg aaaaaatatt aaaaggaatg ggtgttttaa atggccaata agcaagttga
     4621 aatatctatg gctgaatggg atgttatgaa tataatatgg gataaaaaat cagtatcagc
     4681 taatgaaatt gtagttgaaa ttcaaaaata taaagaagtt agtgataaaa cgattagaac
     4741 attaatcaca agactatata aaaaagagat tataaaacga tacaaatcag aaaatattta
     4801 tttttactca tcaaatatta aagaagacga tattaaaatg aaaactgcta aaacctttct
     4861 taataaactg tatggagggg atatgaaaag tttagtgttg aattttgcga aaaatgaaga
     4921 attaaataac aaagaaattg aagaattgcg agatatttta aatgatatta gtaaaaagta
     4981 attagaggta tgtttcaaac ataatacata tgtaaactat gcttgactct tattaaatta
     5041 gttttgttaa tgacatttaa aatatattat taaagatgag agtgtacaga aaataaccat
     5101 tttctgtaca ctcttctttt atgtctaaat aagtaagaat tacataggat tatgtgttca
     5161 aaaacccaac aaaaaatcta tgttcataaa aggccttgta attaagttat ggtacactga
     5221 agatgtatat aggaggtttg tattttgaaa ataggttatg caagagtttc aactggatta
     5281 caaaatttaa atttacagga ggatcgatta aatacatatg gttgtgaaaa gatatttaat
     5341 gaccatatga gtggttcaaa aagtaaaaga cctggtttag ataaagcaat tgaatttgcg
     5401 aggtcaggag atacgattgt tgtttggaga ttagatagat tgggacgtaa tatggaggat
     5461 ttaatcacat tagttaatga gcttaacgaa cgaggtgtaa gtttccatag tttagaagaa
     5521 aatataacaa tggataaatc aagttcaact ggacaattat tatttcattt attcgcagca
     5581 tttgcagaat ttgaacgtaa tttaatttta gagcgttctt cagctggccg aattgcagca
     5641 cgtgctagag gccgatatgg aggcagacca gaaaaattaa atcaaaaaga tttaaactta
     5701 cttaagaccc tttatgataa tggcacgcca attaagacaa ttgcagaaca gtggcatgtt
     5761 tcacgtacaa caatttatcg ttacctcaat aaattggagg acaaggaaga tgaaaaacaa
     5821 ggagaagtat ctaactaatt tttctgaagc caaacgtaaa aaagctactc aaaagtacaa
     5881 tattataaaa ccttttatcc taggcgaaca atctttatca agtatttcta aaagtaaagg
     5941 gattgcgtta agcacccttt ataggtggaa taagtcatat aaagaacaag gacttaaagg
     6001 actaatctat gcgacaagag ctgataaagg aacacgtaaa atagaaccaa agataattga
     6061 tgaaattgaa cgccttgcgc ttatgaataa aagaaatagt atagccacaa ttcataggaa
     6121 aatcactaat tactgtaaag aaaataattt tgatatacca agttataaac aaatttatag
     6181 tgttattaaa gcgatgccta agtctgttat tgatttctct catcagggtg aaaaatacta
     6241 tcaaaataag tacgatttaa tacaaattag agaatcctcg agacccaatg aaatatggca
     6301 agcagaccat actttgctag atatctttat attagaccaa aaaggtaata tcaatagacc
     6361 atggctaact attattatgg atgactatag tcgtgcaatt gcaggctatt tcttaagttt
     6421 tgatgccccc aatgctcaaa acacagcatt aacactacac caagcaatat ggaataaaaa
     6481 tgataccaat tggccagtgt gtggtatacc cgaaaaattc tacacagatc atggaagtga
     6541 ctttacttca catcatatgg aacaagtcgc tattgatttg aaaattaact tgatgttttc
     6601 gaaagttggt gttcctcgtg gtcgtggaaa aatagaacga ttctttcaga cagttaatca
     6661 aactttctta gaacaactgc ctggatatat aaacaataat gatactccta gtaatctaat
     6721 aaattttcac aattttgaag aaaaattacg ttacttttta attgaagatt ataatcaaaa
     6781 agaacatagt actattcata ccacgcctat cagtcattgg aatagtaatc actttttccc
     6841 taatatgcca agtagcttag aacaacttga tttattattg ttggaaatac ctaaatctag
     6901 aaaagttcat tcagatggca ttcattttca aggttttcga tacagtaata ctaatctaga
     6961 agcttatgta ggtgaatatg tactgattcg ttataaccca aatgatatgg ctgaaatacg
     7021 tgtgttttat agagatgaat ttctttgtac tgctatatgt ccagaaatag ctgattactc
     7081 catagatata aaagacatac agcacgctcg tagtcagaga agaaaacact taaaacaaaa
     7141 tattgctagt ccaagtacca cggaattaat taaggaagaa aaaattgtgg ttattcacct
     7201 caagaaacga ctaaaaacgt caaaaaatta aagagatatc gtaatgacta aaaatcaaaa
     7261 tttcattgaa acgaaagagt ataaacgctt tgctgaattt tgtgatgctt gtattaaata
     7321 tcagtatatt ggtatatgtt atggtcaacc tggtgtcgga aaaactttat cgtctaggta
     7381 ttacacaaat tgggatacta ttgaaaaaca agttaaccat agaggttggg aagatttagc
     7441 tagtaaaacg accgatgaca tactatcggt ggataaaata ttttataatg caccagcaga
     7501 aaaacaaact aaattaagga atgatttata tagtattact gcaatcattg atttgggtca
     7561 aaaattacat gttgtaaata agtatggaca tgaacatagt aaacattata gtgatatgtt
     7621 taaatatatt gatttaatta tagtagatga gattgatcgc cttaaagtgc aacatttaga
     7681 gcaattaaga gctatttatg atgaacataa tttagcaatg atatttattg gtatgccggg
     7741 tatagagaaa aactatctcg ttatcctcaa ctatattcgc gtataggttt tgcgcatgaa
     7801 tttgataatc taagtaaaga tgagacgcat catatattag aatataagtg gcaagactta
     7861 ggatttgatt taaaactcga agactttact gattatgagg caataacgac gattattaaa
     7921 attacaaaag ggaattttag gctgattcat cgtttatttg cgcagataga cagaattatg
     7981 gatataaatg gtttagataa aataagtaca gaagttgtag aaacagctag agatagttta
     8041 gttataggta ttcgataata gaaaaagcaa cgcattttaa tatagtgcgt tgcttttctc
     8101 atttattagg taaagtcatt ctcatatatc gagtaaagtg acaacaatta tatatgtatg
     8161 attagggtgt acttatatca ttcatataaa tgtttattta taccctcaat aaaaatatta
     8221 tatgctttta agcacctatc acattcctta taaaaatgtt tattcaatcc tttaatatcg
     8281 actagcgtag tcttataatt ttttgtaaca attttaaatc ctcttcgtaa aagcttaatt
     8341 taaaatgacc ggcttgagct aatggctttt ttccttgttt aattaaaatc aatatgtttt
     8401 ttaaatgttt taaaaagttt ttataatcat aaacttttat tttcatgaat gatttatgtg
     8461 gattattttc ataatttagc aggtagtttt ctatatcttc aatataacta tcatcaaatg
     8521 gtgtgtgctg gaaataaaaa gtttttacat acatgaatat tttataaagt tcttctttca
     8581 aaaaatcata tgtatctaaa tctctttgta tagcatccaa tttttttaat tttttacatt
     8641 tttaccacaa tcctgtactc ttatccatcc actattttct ttaatttcac taggtacact
     8701 ttgcattaaa gtctgagata ctttactttt taattccgaa atatcattaa tatttggact
     8761 aattagtcta ttttctttaa cttttgtctt aaactcatct aattttttag acttttccgc
     8821 ggattcggta gatgctttat tcatctcaaa aacatatata ggtttaccta aagatttagc
     8881 aaaattgtac tccatttctg tatagctaat attttcttca ctatcaattg ttccataact
     8941 agaacctaac aataatatca ctgcatctga ttcattgatc cattgtgtta ttatttccca
     9001 ttggctttta ctacttgagt taaaaagttc catacctgct ggaatattat tactgtttaa
     9061 aactgcttct actactgctt gacgctcttc tattaaatct aaataagttg atgaaataaa
     9121 aatttgatat ttaattttag tattactcat atatgctcct ttaataaaaa atcaatttac
     9181 ataaatatat catatgataa tatccaaaaa gactacttaa aatattatct ttttgcattc
     9241 ctctactaac cagtgttata atctagataa cgaaaatgat taacaattaa tgcaccaatc
     9301 cccacactac tgcaatagtg tggggatttt ttcgatgctg gcttataaag tcgcctatta
     9361 attatttgtt gcgtttacta agccaataag tataatacgc aacagcacag ccactgatga
     9421 ctggtgctat gatgtgaacg aaaatgatta gcaaagtaat gcacctcctc tctgcgtctg
     9481 aattgacgcc tgagagatag gcgacctgta tattatatca tctccgaata tacgatgata
     9541 gataacttcc gataagtcgt cttatgttat ataactttgt tttttatagt atcaagacaa
     9601 gaagaaactc gtttcactcg ttttaaaaac cctcctgatt tttagagaaa aactctctta
     9661 tttcatcgtc tttaataaaa taatatgcca tctttccatc tttataaaaa tcaagtacct
     9721 catttttata taaaagcctt aaatgatgtg aagttgaagc aacactcatt ttcaatatca
     9781 aagaaatatc acaaacacac aactcatctt ctttaatcaa agataatatg attttcaatt
     9841 tcttctcatc acaaattttt tctaaaatgt taagtaattt cttagattta tcatcttcta
     9901 aaaaacttaa agcattgtta actttatcct catgtacaca gatcacatca caagtatttt
     9961 cataactcat ataaaatcac accctaaatt aaaatataaa tcctaaaatt gtttgaatag
    10021 tgtcattttc aataataata aataaaccta aagctatata aatgatagcc ataatccaac
    10081 gactaaattt ctcaacaatt tctccaattc ctgggatatt agctaatttt tgtgcagtaa
    10141 acaccaagaa gaaaattaaa attaaaaaga caaacagagt aagtaataaa ttagtaacac
    10201 ttaatgtcac aaaatacgga acaaataaac caatattatc ggcgccacaa cttgctatcg
    10261 taacaattgc aaccgtacca actaatttag acaatccttt ttcattcaat tctttttagc
    10321 tctcttttct ccttcacaat catcataaat agccacttta attccaagat aaattggtat
    10381 taaacccaat aaacctaata tccacttttc tggaacataa tttaatacaa aagctaaaaa
    10441 caaactaact aatattaaaa taatagaccc taaatattga ccaacataaa tatttctata
    10501 ttcttttcta gtctttgctc tagcaaaaaa tattaataaa attactaata aatcaactgc
    10561 tgtagcaata taaagaacag cagcagcaac aaccgtttga atcataatac acctcattca
    10621 aaaatatttt tgaatgtatt ataacttata tttttaaata atcataggtg ctttattcca
    10681 attgctttat tgacgttgag cctcggaacc cttaacaatc ccaaaacttg tcgaatggtc
    10741 ggcttaatag ctcacgctat gccgacattc gtctgcaagt ttagttaagg gttcttctca
    10801 acgcacaata aattttctcg gcataaatgc gtgtctatgc gtagacatgg agacacttca
    10861 gaattatgga gtgattacat gagtttaact atttttcttt attcagtttt aggaagttta
    10921 ttagcaaatt atatctacga aaaatcttca aaataaataa ctttttcggt tctactttgt
    10981 acactttatc tacctggtag acctaattgt tattgcttta caggtctaaa attcgtcgtt
    11041 ataatctagt taaatcccgt aagggcgcac ttatacgtcg gataaatcga catgtgcaaa
    11101 aacgtaatcg accttcgtcg atttttttat ttcaaaatta aagaaacggc ttgagatatt
    11161 ccgagcagtt ataaaaatta atttgcgttg aatattgcta ctacattctt gaaaaagtga
    11221 tgtagattta tagcccataa cttttttgaa ttacatcgac gatacggcgt cgaaagaaaa
    11281 agctacctca ctttatctgg ggggctttta ttttttatgc ccttattttg aattttaaga
    11341 gggcatttta aagatttagg ggtgattcat atagttttat atctaaaact tatatacgct
    11401 tttaaaacgc aaatatgagc caaataaata tatgctattt tcaaaaacaa aaatttgagc
    11461 aaaaacaata actatttttt agacactgcc catttacatg caaattaaaa attagcataa
    11521 aattctttaa aacttcccca cgttcttcta aattcctgca gggcttttct tatcaaaaac
    11581 ttagaaattt taatttaact ctaaaatctc cgtaagagca taagggaaat ttgtccccat
    11641 caatgaatgg gggatctggc aaagccagat atttcaaggc ttcgaaaatg tttttgtgtg
    11701 gggtcataaa aagctcaagt gtcacacttt tgtgacacta catacagcat ttgtcacaaa
    11761 aataagacag cactttttta caaaaagtaa taaaaaagac atcagttatc actaatgcct
    11821 taaataataa ttttgctttt caaaattgcc gtaatcgaat gtgccttttc ttcttcattt
    11881 gctattttat cttcatcact tgtattaatt aaattgccat cttcagcatc gtctaagttt
    11941 aaaattttat gtttttattt aagcaatcca ccataactta acatacgttt tcgatacaaa
    12001 tctttttcta gatcactgac aatttcttga ttttttcatc gctatcagtt aaaaagtcag
    12061 atgatttaac gaaatatttt gatgtatctt tgattgttat aaaatcattt gaatgattga
    12121 ttaaagatat tatattgttt catgttttta cggcgcatat aaagtgcatg tgtttcttca
    12181 aattcagtta aaattgtttg cattaaataa ccttgcattg acttgaatga ttactaattt
    12241 cattttcgga ctctatatca ttcaagtcat tcatatcatt tatttcagta ttgttagatt
    12301 cagtatagct aagttcagta tcattagatt ctgttttatc gacttcttga agtcggtttt
    12361 tccgacttcc ttgccattgc tgctctcaac agtgttttct tgcttttgaa ttttataaat
    12421 atcatcttct gttacttctg gtttaactaa ataaagttta tttgtcttat ttaaaccttg
    12481 tctttcttgt agtagtaatt cggcttcaat taagttcttt ctttatttta attactttat
    12541 cttttttaca atttaatata ttttgtgggt tttcattttt gtaataaaaa taaatattac
    12601 ctgttttaga atcaacccaa ccatttttaa ttgataaatc taaacgatct ctaagaatac
    12661 cccatgccat ttttgcatca ttggataact tgatatattt aggatttgta aaaaatactt
    12721 tcggtatttg ataaaacttt tctctgtatt cctcatttat gttgtaaagt ttaattgaca
    12781 taataaaaac ctctttccga attttagttt ggtaagaggt aataaaacgc ttacattttt
    12841 tgtgtttatt taataatcta ggtgcttgca ctaagatatt attcattata taatctaagt
    12901 atcgaaaatt atataaataa acagtttcta aacgttttat taccaaaccc cgactattac
    12961 cagtagttgg ggtttttgtt atattaaggt tattatagca ctttgaataa acttaaaaag
    13021 ggaaaatata ggtttataaa cctttgataa acaccataaa ccctttacaa acccttgata
    13081 aaaaggttgg cgaatttata tttttatttg tcgattactt tattattaat cgttataagc
    13141 ttataatatt ttactaaggg tttataaaca ttttataaag ggttgatgat atgaaaagtg
    13201 taaaaaggtt gagtgaagaa ttaggggtta gtaagcaaac gatttttaat aatattaaga
    13261 gattgaatat agagacaata aaacaggaaa acacttcgtt tattaaagaa gataccgata
    13321 tagaaaaaat cattcaaaga gtaaatgaaa ataaaaagaa atatggtttt gaaagtgcta
    13381 ctgaagacaa acaaaaaaag agtcggataa tattaatttt gaatctaaaa gcgatgctca
    13441 aatagtagaa atacttaaaa atcagattaa tactttaaat aatcaaattg aaaaacaaga
    13501 aagtcgtcat gaaacaacaa ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt
    13561 gcttgagaat cagcaagttc tggcattaga gagtaataaa aagattcaaa aattagaaaa
    13621 tcaattagaa aaagaaaaac accttaatta tccctttgat acatctacta acgctagaca
    13681 aaacgttgat gcacaagaaa aaacatatac tactagtcct gtaaatatta accgagatca
    13741 ggaagaaact aaagaaacag agattcaata taaggatata tctggaagtc aaagcgacga
    13801 aagtacacaa ggtgaagaag cacaaagaga agacgtttca gctaatccaa atgacaatga
    13861 tagtgatata gaagaaaaga gtgaagaaac ggaacctaaa aaggggtttt ggagtcgtct
    13921 atttggtaac taattttaat taaaaaggta cgacaagttc ataaattagc cgtgcttttt
    13981 tatgtgaatt gaacttctga taatcatcga ttatgttaac caaacaaaaa gccataaatg
    14041 cctatatgac ggcatttatg gctttttact ttcattatct tttatgcatc ttttatacat
    14101 cgttgatttg acgcgttttc attcttttgc attggcaagt attttgtatc tttattcagt
    14161 tactatttct tttctccaac ctaacaaacc atctttaact ctaataatat gtttgccacg
    14221 ccagacactt cttacttcga aataatacca ttccccgttt ttgttgagga aataaatatc
    14281 ttgataacct tctttaatga catattttgt agcttcttgt ctttgatcgc caaacattat
    14341 caatcccacc cttatattta tttatcttta atatataaca acatttatta atattcatgt
    14401 tatttcatgg aaggagagat ttgttataat gtgaaggtcg tctatctctc agatgtcaat
    14461 tcggcgtaga gaggaggtgc gatttatgaa tgaaattctt gttcacatca tgacaacggc
    14521 aatcagtggt tgtctcgtta cgttatttgg ttattagctc cataaacgtg ataaaaaata
    14581 atatagacga ttaaagccaa ttcaccaaaa aaccccgaac tacggcgaat agttcggggt
    14641 tttgtgcgtt tacaaacgaa attcttgtta cttttagtat atatttcata ttgccttttg
    14701 taaactcttc tattcttatc aatacatttc aaggtgtcgt aaaaatactt tcctttttca
    14761 tattgcctga tgtgcattaa attttgattt taaaatcaac ccatgaacga atgaatggcc
    14821 caaactaaaa atccggcaac aggaaagaaa agccaccaaa aatcataaag aaaatcaact
    14881 atggaaggta ccctgttact ctctctataa tttccctcta aaataacttt tttaaaacgt
    14941 gcatctcctt taattaaatg ctctaaagag attccgaata aatcgctcat agcaatcaaa
    15001 atatctaagg aaggatagtt tttggcactt tcccatttag aaacactttg tctggaaacc
    15061 tttaatatat tggctaattc ctcttgagac catcctttta attctctctg ttcttttata
    15121 gcttcagcta atttcataaa atcactcctt aactcaaact ataattaaaa taattgaaaa
    15181 gtcacgatac ttttagttaa ccaactcgca acgaaaagtt gcgttattcc caattcagtt
    15241 caagttgttt taaaaatcct ctcgttcttt ctctaattgt gggtcgtaat ctttttgagg
    15301 ttgcttttca tatgaccgtt cttctaacca tttaggcgtc ttttcacgcc tcacatattg
    15361 tcttgattta tctatcttgg acatttgagg ttgtcgtttg ttatgaatgc gtttctcagc
    15421 gtcaaatgtg aactctatcc attcaatttt acgccctttt ttcgctttga ttttattgat
    15481 agtaagatta ttaaatatag aacctaattc aataataata ggtttaaaaa catttttgtt
    15541 aatatcagtc atacgataag atttaggtat atctaaacga tttttaaaat catcgatgtg
    15601 aatttttaaa tagcctgtat gtttgtattg tttaagtaat ctaaacatat ttttagaata
    15661 tgtagattta agcctagtca tttcttttaa ttcaaatttt gtaaaattat tagtaattga
    15721 attcaatatg tgttttaaat ttgaagaagt tgatatttct agatattgtt ctcgcttatg
    15781 gattctataa tgattgaata aaacgaatct ttctattaca tcatcatctt catatctaat
    15841 ggttaaattc aacatctttt tatacacatt atctaaatca ttagcaaatc tattaatatt
    15901 acgtgtttct ggactataat tacttaattt ttttaattca tcaaaagaca aacgtaatgt
    15961 attagtatct tgctctttta atttattaca catcgcaaaa aataaattaa tttcagtagc
    16021 tgtaaatcgc cttaatggaa ctaaattcat ttcattttta tatacaactg tctctcctgt
    16081 catgatacag cccctttatt acgaacctaa aggagtatcg tttgaatata cactcccatt
    16141 tgaaaacttt tattcacaat aaactacttt attatcaatg tcaaaccata aaaggagtac
    16201 aactttttaa aacgctcctt ttatgtggca aaaacactcc ttttatgtgg caaaaacact
    16261 ccttttatgt ggcaaaaaca ctccttttat gtggcaaaaa cactccttta ggcattgaaa
    16321 tcccttgttg ctctagggct gaacaagccc ctaaaaaggt ttttaaaaag atttataaaa
    16381 atatattaaa aagttcgagg gggctaccta tttttcatcc taaaaaataa ttaacctcaa
    16441 acaaatgcat ttaaatatct atttttataa tgtataacca tcttctctat cttctttaaa
    16501 aatgatttct cgttcttgtg cttgatattt cttcttaaag aactgttcat cattgttatc
    16561 tatcgtcatt acttcacgta ttttagaatt gtctaaatga ttatcaatat gatttattag
    16621 tgtatgataa cgctcttctt tcatcatact tttaatgatt ttaaaaactt gattgaataa
    16681 cttaagcgta taatttagtt ctttatcttt cttttcattc tctgacaaca aataattata
    16741 acgttgtgct aaatcattaa attcttcaac cagcttttca ttttccatat ggacactagt
    16801 caattcatta actaaacttt cattttgttt ctctgctttt ttaatgactt cccactttta
    16861 atacattcat aatcatctaa tatcatctgt gctgctttaa tttgtttagt gtatttttca
    16921 aaatcagttt tagtaattac aatattgcct gtttcttgct tctctttatg aaaccatcca
    16981 cctacatttt tagttttaat ttcatacatg acactcagaa gctttttaag cgtatctaat
    17041 gatttttggt agttttgtat caatttatca ttttcttgct ttaaataatc ctctatttgc
    17101 ttctagcgca tatgcatttg tttatgatat tctgtttttt gtttataacg gctaacttga
    17161 tcatgttttt cttttgtaag ttgtctagaa attcctcgtt ttaaatcata gccttgctta
    17221 ttaatatacg tattgaatct atcttggaat tcggttaatg cttttttatt acctacaact
    17281 tctttcgcac ttaaacgtcc atctttagta ataggaacta cgccataatg catatgtggt
    17341 gttatctcat ccatatgtac tgtcgcatat aaaagatttt ctttaccgta ttcttcttcc
    17401 aagaacgctt tagcatgctt aaaaaactat tttgtctctt cttcagataa ttgattaaaa
    17461 aacacattat ctgatgtaat taatccatca atatgtttaa tggcatctgt tctaattttg
    17521 cgtttccctt tataattttt tcgattttct catcaatttt tttattaaaa tcaaacttag
    17581 tatcattgac taaatcatag tttaaatatg acttacttaa atcaatatct atattttcat
    17641 aatttttatt ttctctttga atatgtcttt gaatacctct tgtatttgtt tttgatttca
    17701 ctttaacaac tcgaataatt gaataagaca taataaatca acttccactg catatgatta
    17761 taacacctaa acacagaaaa gttttaacat actagactta ttaaaaacca aataagtcat
    17821 taaaaacgtg tgctctgcga ggcttgtttt ttgtcatcat aaaaaaggac tggaaaatcc
    17881 agtccttaaa ttaaaaaact caaaagtaat gactaatcat atttcatatt gtttttctct
    17941 atgtatggct atacctatca atatttctta acttctaagc tcagaaatat tgactatgac
    18001 atcaaatcgt ttcgcaagct ctaaatcatg cgttacgaca atcatagttt tattttcatc
    18061 aagtagcttc aataataaat caataactat ttttccattt ttcgtatcta gtgacccagt
    18121 aggttcatca gctaaaatga ttttcggatc ttttaatatt aatcttgcca atgctactct
    18181 ttgttgttca ccaccgctta gagaactaac aattctcttg atatctaaat ctaggccgac
    18241 cttttttaat acttctttct ttaagttcat attatctttt ttattctttt tgaactttag
    18301 ggctaaatct aaattttgac tgattgtttg attttcaagt aaagcaaaat tttgaaacaa
    18361 ataccctaac gtatatctat aaaaatcgac tttctttttt agtaacttat cttcaatata
    18421 tatgcttcct tgtgatacat cttcgaaccc agcgattatg ttaagtaaag tagattttcc
    18481 agcgccactt tctccaacta aagcatatga ttttcctttt tcaaaattaa agttacatcc
    18541 gtctaaaatg tttttattac cttttttaca aaaacatttt caagttttat cactatcggt
    18601 cacctcattt taaaaagcta ggaatatctt ttgtaatgta ttctatcgaa cgcacatatt
    18661 tccctttatg atttactttc acatattctt ttgtaggatc ataacctaaa aaatccaatt
    18721 tataactctt ttttctccat ttttagagta tacagttata tttctatagt cctgggtatc
    18781 ttttggaact ttggcataag atactttttc ttttaacagt gggttaaaac gatctaaatg
    18841 ctcatttcta accaataaca gactaagtat gatgattaat agtacaattg ttacaataat
    18901 taaagttctt ttcattgttt aaatctccct cattaaatct ttaaagtatt tttcaagata
    18961 tttaatataa gcaatttgaa gtaaatgttg aataatagca atagacatta ttatgaatag
    19021 taatatcttt gaaccaaata aaatatgcgt agtgtaagct aacataatag aaagtaagat
    19081 agaaattgtt aaataacgta cattactgct gaataatgaa taaccatgaa tttttcttaa
    19141 taatagttgc tttttattcc agctaaaata ttgaattgtt tcaaatacag tagctatcaa
    19201 aagaatgaaa acgttaataa taatagtaac tattgttatt atcatttttg ttttcgtttc
    19261 atttaattca tttaacacag aatccttgta attagttata ccgctaattt cttcttctag
    19321 gtgattatct ttaagcaact gtttaagtgt atctaaatct ttaaatagat atccaccttg
    19381 agaaacagca gctaaataaa aatctcctgt taaatcgtca agtgtcaaca acattactat
    19441 tggagaatct agatacccaa atttcaaatt agttgtgcga tcaaaagaaa aaacagatac
    19501 gttttttgac agtacttgca catctacttt tttgttttgt tgcttttgaa agtcaatcca
    19561 tccttggtga tttttttgaa tttcagattt ttgatattgt aaccttggag gaataaacac
    19621 gtttatttta tccgaatgat tgtcaatcat tttaaaatca tgatttatat ttttatagaa
    19681 attcagaaaa ttgttattga taaaaaagac attgccattt tcaggaatgt aattgttttt
    19741 atcgggattg gctatattat tattctttaa aagcaatcca ccaagttgtt cgcttttctt
    19801 aattaaattg tatatattag tttctaaaat ttgtttttct tctgaatttc taatattagg
    19861 agaaatctct aatgtatagt aattatctaa cttttgccag attttttcag agtcatatat
    19921 attctttaac ttcgtataag catttaaatt ttgtgccagt aaaaaagata gtattagcac
    19981 catgatacat ttggtgaagg tacccataaa tattgaaaac ttatatcctt ttttcccttt
    20041 taagattaat ggaatactta acttcaaaag aagactatac gaaatcagcc acagcaatgt
    20101 agtaatacaa gcaaaaacaa aaagcaacac gataaatcta cgaataaaca ttaagaaatc
    20161 caattctaaa ttggctatat gaatgattaa tatattagca ataaagaaaa tagcggtaag
    20221 tactagccaa taaatgattt ttatatgaat attatgaaaa ataatgcgtg tagttgaaaa
    20281 gccatgtagc ttttgaatag cataaaattt caaattatat cctctgtcat ataagaagta
    20341 caaaagatat aatacgccta agaatatgaa aggcactaat aaatcattat ctatgactaa
    20401 ttcaaaaaat aatatgtttc tatttatgta ttcaacttca gatgttaaac cagctttttt
    20461 aattcactcg taagctcttc tacattgaaa tgttcaccaa taatataata ctttcctttt
    20521 atctctctgt ttaataaatc tgatggagtt aaaagtgatg ttttattacg tataaagtca
    20581 gaattatttc gttttgagtt gaaaacaaaa attcttttta ttatcaaaat ctttaacgga
    20641 tttaattatt tgtatatttt gatttttggc gcctgattca atgacatcta acactt
//
