LOCUS       CP141414               20560 bp    DNA     circular BCT 10-JAN-2024
DEFINITION  Staphylococcus aureus strain Sau121 plasmid unnamed1, complete
            sequence.
ACCESSION   CP141414
VERSION     CP141414.1
DBLINK      BioProject: PRJNA1046723
            BioSample: SAMN38508053
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20560)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Nyerere,A., Musila,L. and
            Revathi,G.
  TITLE     Displacement of hospital-acquired methicillin-resistant
            Staphylococcus aureus clones by heterogenous community strains in
            Kenya over a 13-year period
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20560)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Musila,L. and Rivathi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2023) Pathology, Aga Khan University, Nairobi, 3rd
            Parklands Avenue, Nairobi, Nairobi 00100, Kenya
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 21-MAR-2023
            Assembly Method                   :: FLYE v. 2.9.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 35x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/06/2023 16:21:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,876
            CDSs (total)                      :: 2,793
            Genes (coding)                    :: 1,823
            CDSs (with protein)               :: 1,823
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 970
            CDSs (without protein)            :: 970
            Pseudo Genes (ambiguous residues) :: 0 of 970
            Pseudo Genes (frameshifted)       :: 920 of 970
            Pseudo Genes (incomplete)         :: 51 of 970
            Pseudo Genes (internal stop)      :: 31 of 970
            Pseudo Genes (multiple problems)  :: 27 of 970
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            NCBI analysis of this genome has determined that >30% of the
            predicted CDS features contain frameshifts, which is well above the
            usually observed value of <10%.
FEATURES             Location/Qualifiers
     source          1..20560
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Sau121"
                     /isolation_source="clinical"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya: Nairobi"
                     /lat_lon="1.2921 S 36.8219 E"
                     /collection_date="2019"
                     /collected_by="Aga Khan University Hospital, Nairobi"
                     /note="genotype: MRSA"
     gene            join(20406..20560,1..4)
                     /locus_tag="UM772_14240"
     CDS             join(20406..20560,1..4)
                     /locus_tag="UM772_14240"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRM95485.1"
                     /translation="MRWKSMIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSI
                     ENRPVLQ"
                     /name="recombinase family protein"
     gene            43..432
                     /locus_tag="UM772_14245"
     CDS             43..432
                     /locus_tag="UM772_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRM95486.1"
                     /translation="MIHTVNYLKDKEVQLMITSLPMMNEVVGNPLLDKFMKDLIIQILA
                     MVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQS
                     ISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            845..1138
                     /locus_tag="UM772_14250"
     CDS             845..1138
                     /locus_tag="UM772_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WRM95487.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            1213..1479
                     /locus_tag="UM772_14255"
     CDS             1213..1479
                     /locus_tag="UM772_14255"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM95488.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKNFCFQLKTK"
                     /name="hypothetical protein"
     gene            2285..2596
                     /locus_tag="UM772_14260"
     CDS             2285..2596
                     /locus_tag="UM772_14260"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM95489.1"
                     /translation="MLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHDFKMID
                     NHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFLLIAQLI"
                     /name="hypothetical protein"
     gene            2626..3141
                     /locus_tag="UM772_14265"
     CDS             2626..3141
                     /locus_tag="UM772_14265"
                     /inference="COORDINATES: protein motif:HMM:NF018897.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="WRM95490.1"
                     /translation="MLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEISG
                     ITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIHG
                     YSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEKY
                     FKDLMREI"
                     /name="DUF1430 domain-containing protein"
     gene            3145..3354
                     /locus_tag="UM772_14270"
     CDS             3145..3354
                     /locus_tag="UM772_14270"
                     /inference="COORDINATES: protein motif:HMM:TIGR01655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WRM95491.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKRVINWIF"
                     /name="YxeA family protein"
     gene            3467..4092
                     /locus_tag="UM772_14275"
                     /pseudo=""
     CDS             3467..4092
                     /locus_tag="UM772_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /name="ABC transporter ATP-binding protein"
     gene            4330..5258
                     /gene="mobV"
                     /locus_tag="UM772_14280"
                     /pseudo=""
     CDS             4330..5258
                     /gene="mobV"
                     /locus_tag="UM772_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010889940.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            5259..5597
                     /locus_tag="UM772_14285"
     CDS             5259..5597
                     /locus_tag="UM772_14285"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WRM95496.1"
                     /translation="MTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKELNYTLKLFNQ
                     VFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQAQEREIIFKE
                     DREDGYTL"
                     /name="recombinase"
     gene            5978..6838
                     /locus_tag="UM772_14290"
     CDS             5978..6838
                     /locus_tag="UM772_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WRM95492.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            6925..7266
                     /locus_tag="UM772_14295"
     CDS             6925..7266
                     /locus_tag="UM772_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WRM95493.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(7505..7576)
                     /locus_tag="UM772_14300"
     CDS             complement(7505..7576)
                     /locus_tag="UM772_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRM95495.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            7725..7910
                     /locus_tag="UM772_14305"
     CDS             7725..7910
                     /locus_tag="UM772_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM95494.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(8129..8871)
                     /locus_tag="UM772_14310"
                     /pseudo=""
     CDS             complement(8129..8871)
                     /locus_tag="UM772_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /name="DUF536 domain-containing protein"
     gene            9281..9957
                     /locus_tag="UM772_14315"
                     /pseudo=""
     CDS             9281..9957
                     /locus_tag="UM772_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            9968..10250
                     /locus_tag="UM772_14320"
                     /pseudo=""
     CDS             9968..10250
                     /locus_tag="UM772_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            11456..12072
                     /gene="cadD"
                     /locus_tag="UM772_14325"
                     /pseudo=""
     CDS             11456..12072
                     /gene="cadD"
                     /locus_tag="UM772_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            12091..12437
                     /locus_tag="UM772_14330"
                     /pseudo=""
     CDS             12091..12437
                     /locus_tag="UM772_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]; GO_process: GO:0006355 -
                     regulation of DNA-templated transcription [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            12606..12698
                     /locus_tag="UM772_14335"
     CDS             12606..12698
                     /locus_tag="UM772_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRM95480.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            12910..13095
                     /locus_tag="UM772_14340"
     CDS             12910..13095
                     /locus_tag="UM772_14340"
                     /inference="COORDINATES: protein motif:HMM:NF024668.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WRM95481.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMEQLIV
                     KKILAIQKWSTILLNL"
                     /name="DUF4062 domain-containing protein"
     gene            13068..13682
                     /locus_tag="UM772_14345"
     CDS             13068..13682
                     /locus_tag="UM772_14345"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="WRM95482.1"
                     /translation="MEYNFAKSLGKPIYVFEMNKASTESAEKSKKLDEFKTKVKENRLI
                     SPNINDISELKSKVSQTLMQSVPSEIKENSGWIRVQDCGKNVKKLKKLDAIQRDLDTYD
                     FLKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSFMKIKVYDYKNFLK
                     HLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKIIRLR"
                     /name="serine/threonine protein kinase"
     gene            complement(13906..14720)
                     /locus_tag="UM772_14350"
                     /pseudo=""
     CDS             complement(13906..14720)
                     /locus_tag="UM772_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity [Evidence
                     IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            complement(14713..16154)
                     /locus_tag="UM772_14355"
                     /pseudo=""
     CDS             complement(14713..16154)
                     /locus_tag="UM772_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(16126..16718)
                     /locus_tag="UM772_14360"
                     /pseudo=""
     CDS             complement(16126..16718)
                     /locus_tag="UM772_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(16981..17361)
                     /gene="blaI"
                     /locus_tag="UM772_14365"
     ARG             complement(16985..17361)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(17351..18166)
                     /locus_tag="UM772_14370"
     CDS             complement(17351..18166)
                     /locus_tag="UM772_14370"
                     /inference="COORDINATES: protein motif:HMM:NF013100.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0008658 - penicillin binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="WRM95484.1"
                     /translation="MYFYFFIMIIQSQFLMGQSLTDYNYKKPLQSDYQILDESKNFGSN
                     SGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFGLDRHIISDKNSRMSWNHKH
                     YLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQLKQLNYGNENLGSYKSYWME
                     DSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKY
                     NNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKILKGMGVLNGQ"
                     /name="penicillin-binding transpeptidase domain-containing
                     protein"
     gene            complement(18142..19146)
                     /locus_tag="UM772_14375"
                     /pseudo=""
     CDS             complement(18142..19146)
                     /locus_tag="UM772_14375"
                     /inference="COORDINATES: protein motif:HMM:NF017390.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /name="M56 family metallopeptidase"
     gene            19211..20053
                     /gene="blaZ"
                     /locus_tag="UM772_14380"
                     /pseudo=""
     CDS             19211..20053
                     /gene="blaZ"
                     /locus_tag="UM772_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     ARG             19812..20053
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.5"
                     /coverage="28.47"
     BGC             1..6138
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          10305..10452
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          5979..6838
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(8130..8871)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4331..4605
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 gtagtagaat ccattgattg tttaggtcgt aattatgatg aagtgattca taccgttaat
       61 tatttaaaag acaaagaagt acaattaatg attactagct tacctatgat gaatgaagtg
      121 gttggcaatc cattactgga taagtttatg aaagatttaa ttattcaaat attagcaatg
      181 gtttcagaac aagagagaaa tgaaagtaaa cgtcgacaag cgcaaggaat tcaagttgcg
      241 aaggaaaaag gcgtatataa agggcgcccc ttactttatt caccaaatgc taaagatcca
      301 cagaaacgta ttatttatca tcgcgttgta gaaatgttag aagaaggcca atcaattagt
      361 aaaattgcga aagaagtaaa tataacaagg cagacgattt acagaattaa aaacgataat
      421 gatttgattt aataaacttt gtttcaatgc aactgagagc ttctcacagc gtctcaaaac
      481 agatgattat aatctattat gagtttttaa taataagaca agaaaagaga gcgtaaatat
      541 gctctctctt ttctcattaa cgaatgttta taacgcaatc atgatgagag tattaataca
      601 gttaattatt tgaaatactt tagtttatat aatgttgaat tataggtagt gaaattgtat
      661 ttattataca ttgtcatatc gttgtttaat gatagttaat ttaaggataa tagaattaat
      721 attatatata gatgaacaaa acaagcaaca gagcagaaaa aacactttta gattattttt
      781 actcattctc tattttattt atttttgcta taataaataa agaatattaa atgtaggtgt
      841 ttttatgaaa aagaaatttg tttctagttg tattgctagt acaatcttat tcggcacttt
      901 attaggtgta acttataaag ctgaagctgc aacagtacat gtagctggtg gtgtttggag
      961 ccatggtatt ggaaaacatt acgtatggtc ttattatagt cacaataaaa gaaatcatgg
     1021 ttcaacagca gtagggaaat attcatcttt tagtggtgtt gctcgacctg gtgttcaatc
     1081 taaggcatct gctccaaagg cttggggtgg aaacaaaaca ttttatagtc ttcactaatt
     1141 acatatatta attaaggaga atagacagaa ttaagtaaac ttaattctgt ctattctctt
     1201 gaaagaggca atatgaaaaa attcaaatta tttttagatt ttagtacttt attattaatt
     1261 tcagggctat tatttttatt tttcttcaaa gaaaatgaag aaattatacc tgaaagttcc
     1321 aatattttaa caatctctaa ttgggataaa tctaacagta aatcaaaagt gttagatgtc
     1381 attgaatcag gcgccaaaaa tcaaaatata caaataatta aatccgttaa agattttgat
     1441 aataaaaaga atttttgttt tcaactcaaa acgaaataat tctgacttta tacgtaataa
     1501 aacatcactt ttaactccat cagatttatt aaacagagag ataaaaggaa agtattatat
     1561 tattggtgaa catttcaatg tagaagagct tacgagtgaa ttaaaaaagc tggtttaaca
     1621 tctgaagttg aatacataaa tagaaacata ttattttttg aattagtcat agataatgat
     1681 ttattagtgc ctttcatatt cttaggcgta ttatatcttt tgtacttctt atatgacaga
     1741 ggatataatt tgaaatttta tgctattcaa aagctacatg gcttttcaac tacacgcatt
     1801 atttttcata atattcatat aaaaatcatt tattggctag tacttaccgc tattttcttt
     1861 attgctaata tattaatcat tcatatagcc aatttagaat tggatttctt aatgtttatt
     1921 cgtagattta tcgtgttgct ttttgttttt gcttgtatta ctacattgct gtggctgatt
     1981 tcgtatagtc ttcttttgaa gttaagtatt ccattaatct taaaagggaa aaaaggatat
     2041 aagttttcaa tatttatggg taccttcacc aaatgtatca tggtgctaat actatctttt
     2101 tactggcaca aaatttaaat gcttatacga agttaaagaa tatatatgac tctgaaaaat
     2161 ctggcaaaag ttagataatt actatacatt agagatttct cctaatatta gaaattcaga
     2221 agaaaaacaa attttagaaa ctaatatata caatttaatt aagaaaagcg aacaacttgg
     2281 tggattgctt ttaaagaata ataatatagc caatcccgat aaaaacaatt acattcctga
     2341 aaatggcaat gtctttttta tcaataacaa ttttctgaat ttctataaaa atataaatca
     2401 tgattttaaa atgattgaca atcattcgga taaaataaac gtgtttattc ctccaaggtt
     2461 acaatatcaa aaatctgaaa ttcaaaaaaa tcaccaagga tggattgact ttcaaaagca
     2521 acaaaacaaa aaagtagatg tgcaagtact gtcaaaaaac gtatctgttt ttcttttgat
     2581 cgcacaacta atttgaaatt tgggtatcta gattctccaa tagtaatgtt gttgacactt
     2641 gacgatttaa caggagattt ttatttagct gctgtttctc aaggtggata tctatttaaa
     2701 gatttagata cacttaaaca gttgcttaaa gataatcacc tagaagaaga aattagcggt
     2761 ataactaatt acaaggattc tgtgttaaat gaattaaatg aaacgaaaac aaaaatgata
     2821 ataacaatag ttactattat tattaacgtt ttcattcttt tgatagctac tgtatttgaa
     2881 acaattcaat attttagctg gaataaaaag caactattat taagaaaaat tcatggttat
     2941 tcattattca gcagtaatgt acgttattta acaatttcta tcttactttc tattatgtta
     3001 gcttacacta cgcatatttt atttggttca aagatattac tattcataat aatgtctatt
     3061 gctattattc aacatttact tcaaattgct tatattaaat atcttgaaaa atactttaaa
     3121 gatttaatga gggagattta aacaatgaaa agaactttaa ttattgtaac aattgtacta
     3181 ttaatcatca tacttagtct gttattggtt agaaatgagc atttagatcg ttttaaccca
     3241 ctgttaaaag aaaaagtatc ttatgccaaa gttccaaaag atacccagga ctatagaaat
     3301 ataactgtat actctaaaaa tggagaaaaa agagttataa attggatttt ttaggttatg
     3361 atcctacaaa agaatatgtg aaagtaaatc ataaagggaa atatgtgcgt tcgatagaat
     3421 acattacaaa agatattcct agctttttaa aatgaggtga ccgatagtga taaaacttga
     3481 aaatgttttt gtaaaaaagg taataaaaac attttagacg gatgtaactt taattttgaa
     3541 aaaggaaaat catatgcttt agttggagaa agtggcgctg gaaaatctac tttacttaac
     3601 ataatcgctg ggttcgaaga tgtatcacaa ggaagcatat atattgaaga taagttacta
     3661 aaaaagaaag tcgattttta tagatatacg ttagggtatt tgtttcaaaa ttttgcttta
     3721 cttgaaaatc aaacaatcag tcaaaattta gatttagccc taaagttcaa aaagaataaa
     3781 aaagataata tgaacttaaa gaaagaagta ttaaaaaagg tcggcctaga tttagatatc
     3841 aagagaattg ttagttctct aagcggtggt gaacaacaaa gagtagcatt ggcaagatta
     3901 atattaaaag atccgaaaat cattttagct gatgaaccta ctgggtcact agatacgaaa
     3961 aatggaaaaa tagttattga tttattattg aagctacttg atgaaaataa aactatgatt
     4021 gtcgtaacgc atgatttaga gcttgcgaaa cgatttgatg tcatagtcaa tatttctgag
     4081 cttagaagtt aagaaatatt gataggtata gccatacata gagaaaaaac aatatgaaat
     4141 atgattagtc attacttttg agttttttaa tttaaggact ggattttcca gtcctttttt
     4201 atgatgacaa aaaacaagcc tcgcagagca cacgttttta atgacttatt tggtttttaa
     4261 taagtctagt atgttaaaac ttttctgtgt ttaggtgtta taatcatatg cagtggaagt
     4321 tgatttatta tgtcttattc aattattcga gttgttaaag tgaaatcaaa aacaaataca
     4381 agaggtattc aaagacatat tcaaagagaa aataaaaatt atgaaaatat agatattgat
     4441 ttaagtaagt catatttaaa ctatgattta gtcaatgata ctaagtttga ttttaataaa
     4501 aaaattgatg agaaaatcga aaaaaattat aaagggaaac gcaaaattag aacagatgcc
     4561 attaaacata ttgatggatt aattacatca gataatgtgt tttttaatca attatctgaa
     4621 gaagagacaa aatagttttt taagcatgct aaagcgttct tggaagaaga atacggtaaa
     4681 gaaaatcttt tatatgcgac agtacatatg gatgagataa caccacatat gcattatggc
     4741 gtagttccta ttactaaaga tggacgttta agtgcgaaag aagttgtagg taataaaaaa
     4801 gcattaaccg aattccaaga tagattcaat acgtatatta ataagcaagg ctatgattta
     4861 aaacgaggaa tttctagaca acttacaaaa gaaaaacatg atcaagttag ccgttataaa
     4921 caaaaaacag aatatcataa acaaatgcat atgcgctaga agcaaataga ggattattta
     4981 aagcaagaaa atgataaatt gatacaaaac taccaaaaat cattagatac gcttaaaaag
     5041 cttctgagtg tcatgtatga aattaaaact aaaaatgtag gtggatggtt tcataaagag
     5101 aagcaagaaa caggcaatat tgtaattact aaaactgatt ttgaaaaata cactaaacaa
     5161 attaaagcag cacagatgat attagatgat tatgaatgta ttaaaagtgg gaagtcatta
     5221 aaaaagcaga gaaacaaaat gaaagtttag ttaatgaatt gactagtgtc catatggaaa
     5281 atgaaaagct ggttgaagaa tttaatgatt tagcacaacg ttataattat ttgttgtcag
     5341 agaatgaaaa gaaagataaa gaactaaatt atacgcttaa gttattcaat caagttttta
     5401 aaatcattaa aagtatgatg aaagaagagc gttatcatac actaataaat catattgata
     5461 atcatttaga caattctaaa atacgtgaag taatgacgat agataacaat gatgaacagt
     5521 tctttaagaa gaaatatcaa gcacaagaac gagaaatcat ttttaaagaa gatagagaag
     5581 atggttatac attataaaaa tagatattta aatgcatttg tttgaggtta attatttttt
     5641 aggatgaaaa ataggtagcc ccctcgaact ttttaatata tttttataaa tcttttaaaa
     5701 acctttttag gggcttgtta atccctagag caacaaggga tttcaatgcc taaaggagtg
     5761 tttttgccac ataaaaggag tgtttttgcc acataaaagg agtgtttttg ccacataaaa
     5821 ggagtgtttt tgccacataa aaggagtgtt ttaaaagttg tactcctttt atggtttgac
     5881 attgataata aagtagttta ttgtgaataa aagttttcaa atgggagtgt atattcaaac
     5941 gatactcctt taggttcgta ataaaggggg ctgtatcatg acaggagaga cagttgtata
     6001 taaaaatgaa atgaatttag ttccattaag gcgatttaca gctactgaaa ttaatttatt
     6061 ttttgcgatg tgtaataaat taaaagagca agatactaat acattacgtt tgtcttttga
     6121 tgaattaaaa aaattaagta attatagtcc agaaacacgt aatattaata gatttgctaa
     6181 tgatttagat aatgtgtata aaaagatgtt gaatttaacc attagatatg aagatgatga
     6241 tgtaatagaa agattcgttt tattcaatca ttatagaatc cataagcgag aacaatatct
     6301 agaaatatca acttcttcaa atttaaaaca catattgaat tcaattacta ataattttac
     6361 aaaatttgaa ttaaaagaaa tgactaggct taaatctaca tattctaaaa atatgtttag
     6421 attacttaaa caatacaaac atacaggcta tttaaaaatt cacatcgatg attttaaaaa
     6481 tcgtttagat atacctaaat cttatcgtat gactgatatt aacaaaaatg tttttaaacc
     6541 tattattatt gaattaggtt ctatatttaa taatcttact atcaataaaa tcaaagcgaa
     6601 aaaagggcgt aaaattgaat ggatagagtt cacatttgac gctgagaaac gcattcataa
     6661 caaacgacaa cctcaaatgt ccaagataga taaatcaaga caatatgtga ggcgtgaaaa
     6721 gacgcctaaa tggttagaag aacggtcata tgaaaagcaa cctcaaaaag attacgaccc
     6781 acaattagag aaagaacgag aggatttttt aaaacaactt gaactgaatt gggaataacg
     6841 caacttttcg ttgcgagttg gttaactaaa agtatcgtga cttttcaatt attttaatta
     6901 tagtttgagt taaggagtga ttttatgaaa ttagctgaag ctataaaaga acagagagaa
     6961 ttaaaaggat ggtctcaaga ggaattagcc aatatattaa aggtttccag acaaagtgtt
     7021 tctaaatggg aaagtgccaa aaactatcct tccttagata ttttgattgc tatgagcgat
     7081 ttattcggaa tctctttaga gcatttaatt aaaggagatg cacgttttaa aaaagttatt
     7141 ttagagggaa attatagaga gagtaacagg gtaccttcca tagttgattt tctttatgat
     7201 ttttggtggc ttttctttcc tgttgccgga tttttagttt gggccattca ttcgttcatg
     7261 ggttgatttt aaaatcaaaa tttaatgcac atcaggcaat atgaaaaagg aaagtatttt
     7321 tacgacacct tgaaatgtat tgataagaat agaagagttt acaaaaggca atatgaaata
     7381 tatactaaaa gtaacaagaa tttcgtttgt aaacgcacaa aaccccgaac tattcgccgt
     7441 agttcggggt tttttggtga attggcttta atcgtctata ttatttttta tcacgtttat
     7501 ggagctaata accaaataac gtaacgagac aaccactgat tgccgttgtc atgatgtgaa
     7561 caagaatttc attcataaat cgcacctcct ctctacgccg aattgacatc tgagagatag
     7621 acgaccttca cattataaca aatctctcct tccatgaaat aacatgaata ttaataaatg
     7681 ttgttatata ttaaagataa ataaatataa gggtgggatt gataatgttt ggcgatcaaa
     7741 gacaagaagc tacaaaatat gtcattaaag aaggttatca agatatttat ttcctcaaca
     7801 aaaacgggga atggtattat ttcgaagtaa gaagtgtctg gcgtggcaaa catattatta
     7861 gagttaaaga tggtttgtta ggttggagaa aagaaatagt aactgaataa agatacaaaa
     7921 tacttgccaa tgcaaaagaa tgaaaacgcg tcaaatcaac gatgtataaa agatgcataa
     7981 aagataatga aagtaaaaag ccataaatgc cgtcatatag gcatttatgg ctttttgttt
     8041 ggttaacata atcgatgatt atcagaagtt caattcacat aaaaaagcac ggctaattta
     8101 tgaacttgtc gtaccttttt aattaaaatt agttaccaaa tagacgactc caaaacccct
     8161 ttttaggttc cgtttcttca ctcttttctt ctatatcact atcattgtca tttggattag
     8221 ctgaaacgtc ttctctttgt gcttcttcac cttgtgtact ttcgtcgctt tgacttccag
     8281 atatatcctt atattgaatc tctgtttctt tagtttcttc ctgatctcgg ttaatattta
     8341 caggactagt agtatatgtt ttttcttgtg catcaacgtt ttgtctagcg ttagtagatg
     8401 tatcaaaggg ataattaagg tgtttttctt tttctaattg attttctaat ttttgaatct
     8461 ttttattact ctctaatgcc agaacttgct gattctcaag caattttgat ctttcttgca
     8521 actcttttct gtaaaattca attgttgttt catgacgact ttcttgtttt tcaatttgat
     8581 tatttaaagt attaatctga tttttaagta tttctactat ttgagcatcg cttttagatt
     8641 caaaattaat attatccgac tctttttttg tttgtcttca gtagcacttt caaaaccata
     8701 tttcttttta ttttcattta ctctttgaat gattttttct atatcggtat cttctttaat
     8761 aaacgaagtg ttttcctgtt ttattgtctc tatattcaat ctcttaatat tattaaaaat
     8821 cgtttgctta ctaaccccta attcttcact caaccttttt acacttttca tatcatcaac
     8881 cctttataaa atgtttataa acccttagta aaatattata agcttataac gattaataat
     8941 aaagtaatcg acaaataaaa atataaattc gccaaccttt ttatcaaggg tttgtaaagg
     9001 gtttatggtg tttatcaaag gtttataaac ctatattttc ccttttaaag tttattcaaa
     9061 gtgctataat aaccttaata taacaaaaac cccaactact ggtaatagtc ggggtttggt
     9121 aataaaacgt ttagaaactg tttatttata taattttcga tacttagatt atataatgaa
     9181 taatatctta gtgcaagcac ctagattatt aaataaacac aaaaaatgta agcgttttat
     9241 tacctcttac caaactaaaa ttcggaaaga ggtttttatt atgtcaatta aactttacaa
     9301 cataaatgag gaatacagag aaaagtttta tcaaataccg aaagtatttt ttacaaatcc
     9361 taaatatatc aagttatcca atgatgcaaa aatggcatgg ggtattctta gagatcgttt
     9421 agatttatca attaaaaatg gttgggttga ttctaaaaca ggtaatattt atttttatta
     9481 caaaaatgaa aacccacaaa atatattaaa ttgtaaaaaa gataaagtaa ttaaaataaa
     9541 gaaagaactt aattgaagcc gaattactac tacaagaaag acaaggttta aataagacaa
     9601 ataaacttta tttagttaaa ccagaagtaa cagaagatga tatttataaa attcaaaagc
     9661 aagaaaacac tgttgagagc agcaatggca aggaagtcgg aaaaaccgac ttcaagaagt
     9721 cgataaaaca gaatctaatg atactgaact tagctatact gaatctaaca atactgaaat
     9781 aaatgatatg aatgacttga atgatataga gtccgaaaat gaaattagta atcattcaag
     9841 tcaatgcaag gttatttaat gcaaacaatt ttaactgaat ttgaagaaac acatgcactt
     9901 tatatgcgcc gtaaaaacat gaaacaatat aatatcttta atcaatcatt caaatgattt
     9961 tataacaatc aaagatacat caaaatattt cgttaaatca tctgactttt taactgatag
    10021 cgatgaaaaa atcaagaaat tgtcagtgat ctagaaaaag atttgtatcg aaaacgtatg
    10081 ttaagttatg gtggattgct taaataaaaa cataaaattt taaacttaga cgatgctgaa
    10141 gatggcaatt taattaatac aagtgatgaa gataaaatag caaatgaaga agaaaaggca
    10201 cattcgatta cggcaatttt gaaaagcaaa attattattt aaggcattag tgataactga
    10261 tgtctttttt attacttttt gtaaaaaagt gctgtcttat ttttgtgaca aatgctgtat
    10321 gtagtgtcac aaaagtgtga cacttgagct ttttatgacc ccacacaaaa acattttcga
    10381 agccttgaaa tatctggctt tgccagatcc cccattcatt gatggggaca aatttccctt
    10441 atgctcttac ggagatttta gagttaaatt aaaatttcta agtttttgat aagaaaagcc
    10501 ctgcaggaat ttagaagaac gtggggaagt tttaaagaat tttatgctaa tttttaattt
    10561 gcatgtaaat gggcagtgtc taaaaaatag ttattgtttt tgctcaaatt tttgtttttg
    10621 aaaatagcat atatttattt ggctcatatt tgcgttttaa aagcgtatat aagttttaga
    10681 tataaaacta tatgaatcac ccctaaatct ttaaaatgcc ctcttaaaat tcaaaataag
    10741 ggcataaaaa ataaaagccc ccagataaag tgaggtagct ttttctttcg acgccgtatc
    10801 gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc aagaatgtag
    10861 tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa gccgtttctt
    10921 taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg tcgatttatc
    10981 cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat tttagacctg
    11041 taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga accgaaaaag
    11101 ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct aaaactgaat
    11161 aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct ccatgtctac
    11221 gcatagacac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac ccttaactaa
    11281 acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg
    11341 gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag cacctatgat
    11401 tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt gtattatgat
    11461 tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt tattagtaat
    11521 tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata tttatgttgg
    11581 tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt ttgtattaaa
    11641 ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt atcttggaat
    11701 taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaga attgaatgaa
    11761 aaaggattgt ctaaattagt tggtacggtt gcaattgtta cgatagcaag ttgtggcgcc
    11821 gataatattg gtttatttgt tccgtatttt gtgacattaa gtgttactaa tttattactt
    11881 actctgtttg tctttttaat tttaattttc ttcttggtgt ttactgcaca aaaattagct
    11941 aatatcccag gaattggaga aattgttgag aaatttagtc gttggattat ggctatcatt
    12001 tatatagctt taggtttatt tattattatt gaaaatgaca ctattcaaac aattttagga
    12061 tttatatttt aatttagggt gtgattttat atgagttatg aaaatacttg tgatgtgatc
    12121 tgtgtacatg aggataaagt taacaatgct ttaagttttt agaagatgat aaatctaaga
    12181 aattacttaa cattttagaa aaaatttgtg atgagaagaa attgaaaatc atattatctt
    12241 tgattaaaga agatgagttg tgtgtttgtg atatttcttt gatattgaaa atgagtgttg
    12301 cttcaacttc acatcattta aggcttttat ataaaaatga ggtacttgat ttttataaag
    12361 atggaaagat ggcatattat tttattaaag acgatgaaat aagagagttt ttctctaaaa
    12421 atcaggaggg tttttgaaac gagtgaaacg agtttcttct tgtcttgata ctataaaaaa
    12481 caaagttata taacataaga cgacttatcg gaagttatct atcatcgtat attcggagat
    12541 gatataatat acaggtcgcc tatctctcag gcgtcaattc agacgcagag aggaggtgca
    12601 ttactttgct aatcattttc gttcacatca tagcaccagt catcagtggc tgtgctgttg
    12661 cgtattatac ttattggctt agtaaacgca acaaataatt aataggcgac tttataagcc
    12721 agcatcgaaa aaatccccac actattgcag tagtgtgggg attggtgcat taattgttaa
    12781 tcattttcgt tatctagatt ataacactgg ttagtagagg aatgcaaaaa gataatattt
    12841 taagtagtct ttttggatat tatcatatga tatatttatg taaattgatt ttttattaaa
    12901 ggagcatata tgagtaatac taaaattaaa tatcaaattt ttatttcatc aacttattta
    12961 gatttaatag aagagcgtca agcagtagta gaagcagttt taaacagtaa taatattcca
    13021 gcaggtatgg aacaattgat agtgaagaaa atattagcta tacagaaatg gagtacaatt
    13081 ttgctaaatc tttaggtaaa cctatatatg tttttgagat gaataaagca tctaccgaat
    13141 ccgcggaaaa gtctaaaaaa ttagatgagt ttaagacaaa agttaaagaa aatagactaa
    13201 ttagtccaaa tattaatgat atttcggaat taaaaagtaa agtatctcag actttaatgc
    13261 aaagtgtacc tagtgaaatt aaagaaaata gtggatggat aagagtacag gattgtggta
    13321 aaaatgtaaa aaaattaaaa aaattggatg ctatacaaag agatttagat acatatgatt
    13381 ttttgaaaga agaactttat aaaatattca tgtatgtaaa aactttttat ttccagcaca
    13441 caccatttga tgatagttat attgaagata tagaaaacta cctgctaaat tatgaaaata
    13501 atccacataa atcattcatg aaaataaaag tttatgatta taaaaacttt ttaaaacatt
    13561 taaaaaacat attgatttta attaaacaag gaaaaaagcc attagctcaa gccggtcatt
    13621 ttaaattaag cttttacgaa gaggatttaa aattgttaca aaaaattata agactacgct
    13681 agtcgatatt aaaggattga ataaacattt ttataaggaa tgtgataggt gcttaaaagc
    13741 atataatatt tttattgagg gtataaataa acatttatat gaatgatata agtacaccct
    13801 aatcatacat atataattgt tgtcacttta ctcgatatat gagaatgact ttacctaata
    13861 aatgagaaaa gcaacgcact atattaaaat gcgttgcttt ttctattatc gaatacctat
    13921 aactaaacta tctctagctg tttctacaac ttctgtactt attttatcta aaccatttat
    13981 atccataatt ctgtctatct gcgcaaataa acgatgaatc agcctaaaat tcccttttgt
    14041 aattttaata atcgtcgtta ttgcctcata atcagtaaag tcttcgagtt ttaaatcaaa
    14101 tcctaagtct tgccacttat attctaatat atgatgcgtc tcatctttac ttagattatc
    14161 aaattcatgc gcaaaaccta tacgcgaata tagttgagga taacgagata gtttttctct
    14221 atacccggca taccaataaa tatcattgct aaattatgtt catcataaat agctcttaat
    14281 tgctctaaat gttgcacttt aaggcgatca atctcatcta ctataattaa atcaatatat
    14341 ttaaacatat cactataatg tttactatgt tcatgtccat acttatttac aacatgtaat
    14401 ttttgaccca aatcaatgat tgcagtaata ctatataaat cattccttaa tttagtttgt
    14461 ttttctgctg gtgcattata aaatatttta tccaccgata gtatgtcatc ggtcgtttta
    14521 ctagctaaat cttcccaacc tctatggtta acttgttttt caatagtatc ccaatttgtg
    14581 taatacctag acgataaagt ttttccgaca ccaggttgac cataacatat accaatatac
    14641 tgatatttaa tacaagcatc acaaaattca gcaaagcgtt tatactcttt cgtttcaatg
    14701 aaattttgat ttttagtcat tacgatatct ctttaatttt ttgacgtttt tagtcgtttc
    14761 ttgaggtgaa taaccacaat tttttcttcc ttaattaatt ccgtggtact tggactagca
    14821 atattttgtt ttaagtgttt tcttctctga ctacgagcgt gctgtatgtc ttttatatct
    14881 atggagtaat cagctatttc tggacatata gcagtacaaa gaaattcatc tctataaaac
    14941 acacgtattt cagccatatc atttgggtta taacgaatca gtacatattc acctacataa
    15001 gcttctagat tagtattact gtatcgaaaa ccttgaaaat gaatgccatc tgaatgaact
    15061 tttctagatt taggtatttc caacaataat aaatcaagtt gttctaagct acttggcata
    15121 ttagggaaaa agtgattact attccaatga ctgataggcg tggtatgaat agtactatgt
    15181 tctttttgat tataatcttc aattaaaaag taacgtaatt tttcttcaaa attgtgaaaa
    15241 tttattagat tactaggagt atcattattg tttatatatc caggcagttg ttctaagaaa
    15301 gtttgattaa ctgtctgaaa gaatcgttct atttttccac gaccacgagg aacaccaact
    15361 ttcgaaaaca tcaagttaat tttcaaatca atagcgactt gttccatatg atgtgaagta
    15421 aagtcacttc catgatctgt gtagaatttt tcgggtatac cacacactgg ccaattggta
    15481 tcatttttat tccatattgc ttggtgtagt gttaatgctg tgttttgagc attgggggca
    15541 tcaaaactta agaaatagcc tgcaattgca cgactatagt catccataat aatagttagc
    15601 catggtctat tgatattacc tttttggtct aatataaaga tatctagcaa agtatggtct
    15661 gcttgccata tttcattggg tctcgaggat tctctaattt gtattaaatc gtacttattt
    15721 tgatagtatt tttcaccctg atgagagaaa tcaataacag acttaggcat cgctttaata
    15781 acactataaa tttgtttata acttggtata tcaaaattat tttctttaca gtaattagtg
    15841 attttcctat gaattgtggc tatactattt cttttattca taagcgcaag gcgttcaatt
    15901 tcatcaatta tctttggttc tattttacgt gttcctttat cagctcttgt cgcatagatt
    15961 agtcctttaa gtccttgttc tttatatgac ttattccacc tataaagggt gcttaacgca
    16021 atccctttac ttttagaaat acttgataaa gattgttcgc ctaggataaa aggttttata
    16081 atattgtact tttgagtagc ttttttacgt ttagcttcag aaaaattagt tagatacttc
    16141 tccttgtttt tcatcttcct tgtcctccaa tttattgagg taacgataaa ttgttgtacg
    16201 tgaaacatgc cactgttctg caattgtctt aattggcgtg ccattatcat aaagggtctt
    16261 aagtaagttt aaatcttttg atttaatttt tctggtctgc ctccatatcg gcctctagca
    16321 cgtgctgcaa ttcggccagc tgaagaacgc tctaaaatta aattacgttc aaattctgca
    16381 aatgctgcga ataaatgaaa taataattgt ccagttgaac ttgatttatc cattgttata
    16441 ttttcttcta aactatggaa acttacacct cgttcgttaa gctcattaac taatgtgatt
    16501 aaatcctcca tattacgtcc caatctatct aatctccaaa caacaatcgt atctcctgac
    16561 ctcgcaaatt caattgcttt atctaaacca ggtcttttac tttttgaacc actcatatgg
    16621 tcattaaata tcttttcaca accatatgta tttaatcgat cctcctgtaa atttaaattt
    16681 tgtaatccag ttgaaactct tgcataacct attttcaaaa tacaaacctc ctatatacat
    16741 cttcagtgta ccataactta attacaaggt cttttatgaa catagatttt ttgttgggtt
    16801 tttgaacaca taatcctatg taattcttac ttatttagac ataaagaaga gtgtacagaa
    16861 aatggttatt ttctgtacac tctcatcttt aataatatat tttaaatgtc attaacaaaa
    16921 ctaatttaat aagagtcaag catagtttac atatgtatta tgtttgaaac atacctctaa
    16981 ttacttttta ctaatatcat ttaaaatatc tcgcaattct tcaatttctt tgttatttaa
    17041 ttcttcattt ttcgcaaaat tcaacactaa acttttcata tcccctccat acagtttatt
    17101 aagaaaggtt ttagcagttt tcattttaat atcgtcttct ttaatatttg atgagtaaaa
    17161 ataaatattt tctgatttgt atcgttttat aatctctttt ttatatagtc ttgtgattaa
    17221 tgttctaatc gttttatcac taacttcttt atatttttga atttcaacta caatttcatt
    17281 agctgatact gattttttat cccatattat attcataaca tcccattcag ccatagatat
    17341 ttcaacttgc ttattggcca tttaaaacac ccattccttt taatattttt tcacttatta
    17401 attcagcatt tttcccagac gggtttccat ctgataaatg tgtagcaaaa taatacttat
    17461 catgatttgt aattacgtaa cctacaaacc acccattatt atacttcccg tttactatac
    17521 ctgtacctgt tttcccatac agttcatact tttcattttt cttaatcaat aatgaagaag
    17581 ataattgatt ctttgctttt ttactaaaat ggttattttg ttccatcata tttttaaaaa
    17641 ctattacttg ttcaagatta gatattttca aactatcttc catccaatag cttttataac
    17701 ttcccaaatt ttcattacca taatttaatt gcttgagttg agccgcagta tagttctttg
    17761 gtatttgatt actaatacgt tcgaagtacc aattaactga attttgcatt gctgtattta
    17821 aatcttgttc cttattccaa gactcgaaaa gataatgttt atgattccat gacatacgtg
    17881 aatttttatc acttataata tgacggtcaa gtccaaacag tgctaaataa attttgtaag
    17941 ttgaatcagg agaatatctt tttctacttt ctttttcatt ataaatatag tatttgtctt
    18001 tcttcatgct gtacataacg aaagatccac tatttgaacc aaaattttta ctttcatcta
    18061 aaatttggta atcgctttgt aagggctttt tataattata atcagttaag gattgcccca
    18121 ttaaaaactg gctttgaatt atcatgataa aaaagtaaaa atacaaataa aaattagaat
    18181 taattttgac tgctttttca gatcggcttc ttttatatta attaatctat ttttgagtaa
    18241 tgatttttta ccattaaatg aatggcttaa tatatttttg ttgaaaaatg aggtttttaa
    18301 tacggagtcc ataatagatt ccgcataagt tttaaattca tttttgttaa tattattaag
    18361 gacaaatcta tcggcttcta cttcattgtc atgaattatc tttcttttta caatatgtac
    18421 taatggattg taactcataa taatagagaa gatattaaag ataattaaat gtaaagtatc
    18481 tctattttta gcatgagcat attcatgcag tattatatat tttagtcttt tatcaattac
    18541 acttttaaaa tatgaactag gaatcaaaat aatatatttc ccataccaaa aagttattgg
    18601 agattgaata gcctctgctt ttcgaatcac aatatttttt atattgatgg ttgaaaagta
    18661 tcgtatctat tttatttttt cattttcgtt tagataaagt gactgtttct ttaaatattt
    18721 aagatataat aaggctttca aaaatttaaa acttaaaata ataactaaaa ctatccaaat
    18781 aactgtgcag atattatcaa ttgaatccca attaaactta tggatatctg ttgcgaactc
    18841 ttgaacaggt ttggtggtaa ttatgttatg gttcaagtcg tgtgacttac tttcaactgt
    18901 gggcgcttga ttattcacat tattaaattt tataaaagag aatttaattg ggataaaagg
    18961 aattaatcca gcaagcacag ttagatacca aactttataa tttaaactat aattaaaata
    19021 gcgttttaat atgtacctaa aaaatactaa caatagaaat ataaaacaaa agcttactac
    19081 actcattatt agtaatttag ccattttgac accttctttc aaatatttat aataaacaat
    19141 tgacatcaat attacaattg taatattatt gttttgtaaa aattacaact gtaatatcgg
    19201 agggtttatt ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg
    19261 taattcaaac aattcacatg ccaaagagtt aaatgattta gaaaaaatat aatgctcata
    19321 ttggtgttta tgctttagat actaaaagtg gtaaggaagt aaaatttaat tcagataaga
    19381 gatttgccta tgcttcgact tcaaaagcga taaatagtgc tattttgtta gaacaagtac
    19441 cttataataa gttaaataaa aaagtacata ttaacaaaga tgatatagtt gcttattctc
    19501 ctattttaga aaaatatgta ggaaaagaca tcactttaaa agaacttatt gaggcttcaa
    19561 tgacatatag tgataataca gcaaacaata aaattataaa agaaatcggt ggaatcaaaa
    19621 aagttaaaca acgtctaaaa gaactaggag ataaagtaac aaatccagtt agatatgaga
    19681 tagaattaaa ttactattcg ccaaagagca aaaaagatac ttcaacgcct gctgctttcg
    19741 gcaagacttt aaataaactt atcgcaaatg gaaaattaag caaaaaaata aaaatttctt
    19801 acttgattta atgtttaata ataaaaacgg agacacttta attaaagatg gtgttccaaa
    19861 agactataag gttgctgata aaagtggtca agcaataaca tatgcttcta gaaatgatgt
    19921 tgcttttgtt tatcctaagg gccaatctga acctattgtt ttagtcattt ttacgaataa
    19981 agacaataaa agtgataagc caaatgataa gttgataagt gaaaccgcca agagtgtaat
    20041 gaaggaattt taatattcta aatgcataat aaatactgat aacatcttat agtttgtatt
    20101 atattttcta ttatcgttga catgtataat tttgatatca aaacctgatt ttccctttat
    20161 tattttcgag atttattttc ttaattctct ttaacaaact agaaatattg tatatacaaa
    20221 aaatcataaa taatagatga atagtttaat tataggtgtt catcaatcga aaaagcaacg
    20281 tatcttattt aaagtgcgtt gctttttctc atttataagg ttaaataatt ctcatatatc
    20341 aagcaaagtg acataattgt tgaatttata gtaactgaaa cgtatgatta gggtgtatat
    20401 taattatgag atggaaatca atgattgttg gctatgcgag agtatcatcg aacgatcaaa
    20461 atttagaaag acaacttgaa aatttaaaga cgttttgtgc tgaaaaaata tttacagaaa
    20521 aacagtctgg gaaatctatt gaaaatagac cagtacttca
//
