LOCUS       CP141402               19416 bp    DNA     circular BCT 10-JAN-2024
DEFINITION  Staphylococcus aureus strain Sau131 plasmid unnamed2, complete
            sequence.
ACCESSION   CP141402
VERSION     CP141402.1
DBLINK      BioProject: PRJNA1046723
            BioSample: SAMN38508060
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19416)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Nyerere,A., Musila,L. and
            Revathi,G.
  TITLE     Displacement of hospital-acquired methicillin-resistant
            Staphylococcus aureus clones by heterogenous community strains in
            Kenya over a 13-year period
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19416)
  AUTHORS   Nyasinga,J., Munshi,Z., Kigen,C., Musila,L. and Rivathi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2023) Pathology, Aga Khan University, Nairobi, 3rd
            Parklands Avenue, Nairobi, Nairobi 00100, Kenya
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 21-MAR-2023
            Assembly Method                   :: FLYE v. 2.9.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 32x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/06/2023 16:08:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,950
            CDSs (total)                      :: 2,871
            Genes (coding)                    :: 1,794
            CDSs (with protein)               :: 1,794
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 1,077
            CDSs (without protein)            :: 1,077
            Pseudo Genes (ambiguous residues) :: 0 of 1,077
            Pseudo Genes (frameshifted)       :: 1,032 of 1,077
            Pseudo Genes (incomplete)         :: 58 of 1,077
            Pseudo Genes (internal stop)      :: 29 of 1,077
            Pseudo Genes (multiple problems)  :: 41 of 1,077
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            NCBI analysis of this genome has determined that >30% of the
            predicted CDS features contain frameshifts, which is well above the
            usually observed value of <10%.
FEATURES             Location/Qualifiers
     source          1..19416
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Sau131"
                     /isolation_source="clinical"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="Kenya: Nyamira"
                     /lat_lon="0.5669 S 34.9341 E"
                     /collection_date="2023"
                     /collected_by="Aga Khan University Hospital, Nairobi"
                     /note="genotype: MRSA"
     gene            complement(join(18967..19416,1..167))
                     /gene="cadD"
                     /locus_tag="UM768_14630"
                     /pseudo=""
     CDS             complement(join(18967..19416,1..167))
                     /gene="cadD"
                     /locus_tag="UM768_14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            complement(1282..1475)
                     /locus_tag="UM768_14635"
                     /pseudo=""
     CDS             complement(1282..1475)
                     /locus_tag="UM768_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            1737..1859
                     /locus_tag="UM768_14640"
     CDS             1737..1859
                     /locus_tag="UM768_14640"
                     /inference="COORDINATES: protein motif:HMM:TIGR04450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM82934.1"
                     /translation="MTKKEISFLEQLQNKNEDMQKFEKQMKKKDLKNKARRQKF"
                     /name="hypothetical protein"
     gene            1834..2274
                     /locus_tag="UM768_14645"
     CDS             1834..2274
                     /locus_tag="UM768_14645"
                     /inference="COORDINATES: protein motif:HMM:TIGR04450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WRM82941.1"
                     /translation="MKLEDKNSKLKYLATEANDKNAYGYIANNAYKNEKTKEIVVSETI
                     YDNYNKKITKFIAEKRSMTENKEGKILINKNYVEYKAEKVDKNRPVTYAGFKWNGKAFA
                     CSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTAFAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(2442..2591)
                     /locus_tag="UM768_14650"
     CDS             complement(2442..2591)
                     /locus_tag="UM768_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM82935.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(3137..3424)
                     /locus_tag="UM768_14655"
                     /pseudo=""
     CDS             complement(3137..3424)
                     /locus_tag="UM768_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(3533..4096)
                     /locus_tag="UM768_14660"
     CDS             complement(3533..4096)
                     /locus_tag="UM768_14660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM82936.1"
                     /translation="MKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSK
                     IERPEVRKSNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKE
                     MLLQEFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLK
                     DLKKLYMIGELKAKRKQSSQCKLI"
                     /name="hypothetical protein"
     gene            complement(4159..4425)
                     /locus_tag="UM768_14665"
     CDS             complement(4159..4425)
                     /locus_tag="UM768_14665"
                     /inference="COORDINATES: protein motif:HMM:NF018653.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WRM82937.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKG"
                     /name="replication initiator protein A"
     gene            4850..5591
                     /locus_tag="UM768_14670"
                     /pseudo=""
     CDS             4850..5591
                     /locus_tag="UM768_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /name="DUF536 domain-containing protein"
     gene            complement(5817..6001)
                     /locus_tag="UM768_14675"
                     /pseudo=""
     CDS             complement(5817..6001)
                     /locus_tag="UM768_14675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(6006..6344)
                     /locus_tag="UM768_14680"
     CDS             complement(6006..6344)
                     /locus_tag="UM768_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WRM82938.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(6589..7197)
                     /locus_tag="UM768_14685"
     CDS             complement(6589..7197)
                     /locus_tag="UM768_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRM82939.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(7683..8582)
                     /locus_tag="UM768_14690"
     CDS             complement(7683..8582)
                     /locus_tag="UM768_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WRM82940.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(8681..10145)
                     /gene="msr(A)"
                     /locus_tag="UM768_14695"
                     /pseudo=""
     CDS             complement(8681..10145)
                     /gene="msr(A)"
                     /locus_tag="UM768_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /name="msr(A)"
     gene            10616..11290
                     /locus_tag="UM768_14700"
     CDS             10616..11290
                     /locus_tag="UM768_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WRM82926.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(11349..11555)
                     /locus_tag="UM768_14705"
                     /pseudo=""
     CDS             complement(11349..11555)
                     /locus_tag="UM768_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(12225..12803)
                     /locus_tag="UM768_14710"
     CDS             complement(12225..12803)
                     /locus_tag="UM768_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WRM82927.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(13067..13447)
                     /gene="blaI"
                     /locus_tag="UM768_14715"
     ARG             complement(13071..13447)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(13437..14231)
                     /locus_tag="UM768_14720"
     CDS             complement(13437..14231)
                     /locus_tag="UM768_14720"
                     /inference="COORDINATES: protein motif:HMM:NF013100.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="WRM82929.1"
                     /translation="MIIQSQFLMGQSLTDYNYKKPLQSDYQILDESKNFGSNSGSFVMY
                     SMKKDKYYIYNEKESRKRYSPDSTYKIYLALFGLDRHIISDKNSRMSWNHKHYLFESWN
                     KEQDLNTAMQNSVNWYFERISNQIPKNYTAAQLKQLNYGNENLGSYKSYWMEDSLKISN
                     LEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVG
                     YVITNHDKYYFATHLSDGNPSGKNAELISEKILKGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            complement(14228..15232)
                     /locus_tag="UM768_14725"
                     /pseudo=""
     CDS             complement(14228..15232)
                     /locus_tag="UM768_14725"
                     /inference="COORDINATES: protein motif:HMM:NF017390.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /name="M56 family metallopeptidase"
     gene            15297..16140
                     /gene="blaZ"
                     /locus_tag="UM768_14730"
                     /pseudo=""
     CDS             15297..16140
                     /gene="blaZ"
                     /locus_tag="UM768_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     gene            complement(16666..17085)
                     /locus_tag="UM768_14735"
     CDS             complement(16666..17085)
                     /locus_tag="UM768_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WRM82930.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            17209..18180
                     /locus_tag="UM768_14740"
     CDS             17209..18180
                     /locus_tag="UM768_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WRM82931.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(18352..18444)
                     /locus_tag="UM768_14745"
     CDS             complement(18352..18444)
                     /locus_tag="UM768_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WRM82932.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18601..18948)
                     /locus_tag="UM768_14750"
     CDS             complement(18601..18948)
                     /locus_tag="UM768_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WRM82933.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     ARG             complement(7687..8582)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9892..10145)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.15"
                     /coverage="17.21"
     ARG             complement(9236..9921)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="97.91"
                     /coverage="46.72"
     ARG             complement(8682..9232)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="37.5"
     ARG             complement(7684..8582)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             15899..16140
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.5"
                     /coverage="28.47"
     Typing          complement(2935..3082)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(3140..3314)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.135"
                     /coverage="94.0"
                     /evalue="4.83e-64"
     Typing          complement(3445..4425)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.39"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4851..5591
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aacaaactaa ctaatattaa aataatagac cctaaatatt gaccaacata aatatctcta
       61 tattcttttc tagtctttgc tctagcaaaa aatattaata aaattactaa taaatcaact
      121 gctgtagcaa tataaagaac agcagcagca acaaccgttt gaatcataat acacctcatt
      181 caaaaatatt tttgaatgta ttataactta tatttttaaa taatcatagg tgctttattc
      241 caattgcttt attgacgttg agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg
      301 tcggcttaat agctcacgct atgccgacat tcgtctgcaa gtttagttaa gggttcttct
      361 caacatcaat aaattttttc ggcataaatg cgtgtctatg cgtagacatg gagacacttc
      421 agaattatgg agtgattaca tgagtttaac tatttttctt tattcagttt taggaagttt
      481 attagcaaat tatatctacg aaaaatcttc aaaataaata actttttcgg ttctactttg
      541 tacactttat ctacctggta gacctaattg ttattgcttt acaggtctaa aattcgtcgt
      601 tataatctag ttaaatcccg taagggcgca cttatacgtc ggataaatcg acatgtgcaa
      661 aaacgtaatc gaccttcgtc gattttttta tttcaaaatt aaagaaacgg cttgagatat
      721 tccgagcagt tataaaaatt aatttgcgtt gaatattgct actacattct tgaaaaagtg
      781 atgtagattt atagcccata acttttttga attacatcga cgatacggcg tcgaaagaaa
      841 aataaataga ccgtatgaaa gaaaaagcta cctcacttta tctggggtag cttttatttt
      901 ttatgccctt attttgaatt ttaagagggc attttaaaga tttaggggtg attcatatag
      961 ttttatatct aaaacttata tatgctttta aaacgcaaat atgagccaaa taaatatatg
     1021 ctattttcaa aaacaaaaat ttgagcaaaa acaataacta tttttagaca ctgcccattt
     1081 acatgcaaat taaaaattag cataaaattc tttaaaactt ccccacgttt ttctaaattc
     1141 ctgtagggcg tttttatcaa aaatcaagac aagaagaaac tcgttcacac tcgtttcaaa
     1201 aaacaagaaa tctaatctat acacctaccg ttttccaacc ccctcaaagc atacaaatta
     1261 aaaacaaaat tattcataat cttactttct tttaacaaaa acataaaaac cataaataga
     1321 caaattaact atcaaaggca ataaacagta taaaaaacca cgaataaatc ttcatcaaca
     1381 tctaaaataa aaaagaataa aacaattaac aaaatactaa ttaacaaacc taaaagtggc
     1441 aaacttttta tatatttttc taaattttca ttcataaaat agactccttt caaaaatatg
     1501 tttataaata tattaaaata aatattgatt ttataaagcg cttacttata caattaaaat
     1561 atcttattat cttggaggta tcaaatgaaa attataaaat tattttcaat aatttccttg
     1621 ttcctactgg tatttagcgc gaatttttct aatgcttacg caaatgaaga acaaaaaagt
     1681 tctttactag aaaatcaaaa gaaaaattga aaagcaaaaa catcgaagta tcacaaatga
     1741 ccaagaaaga aataagtttt ctagaacaat tgcaaaataa aaatgaagat atgcaaaaat
     1801 tcgaaaagca aatgaaaaag aaggatttaa aaaataaagc tagaagacaa aaattctaaa
     1861 ttaaaatatc tagctacaga agcaaatgat aaaaatgcat atggctacat agctaataac
     1921 gcttataaaa atgaaaaaac aaaagaaatt gtagtttctg aaacaatata tgataactac
     1981 aacaaaaaaa tcacaaaatt cattgccgaa aaaagaagta tgactgaaaa caaagaggga
     2041 aaaatactta ttaacaaaaa ttacgttgaa tataaggctg aaaaagttga taaaaacaga
     2101 ccggtaacat atgcaggatt caaatggaac ggcaaagcat tcgcttgtag tatggctgga
     2161 ctttatgcat gtgctcacta ctgtggagta tgggcaatcg taaatccaat agccggcggt
     2221 gtatgtgaag cagtttgcgg aactgcattt gcagctggat gctctgtagg ttgattttat
     2281 tccaattgtt ttattgacgt tgagcctcgg aacccttaac aatcccaaaa cttgtcgaat
     2341 ggtcggctta atagctcacg ctatgccgac attcgtctgc aagtttagtt aagggttctt
     2401 ctcaacatca ataaattttt tcggcataaa tacgatgttc cttatttatc ctcataaaaa
     2461 acaatagctg aaatatataa ccaattactg tgtgtttgaa tttctaatac atgaatatca
     2521 ttctttaaaa acctattaac ttgtttatct aattgacgat gagtaaaagt agcgaaagtt
     2581 ttaatcttca tgatatctct ccttttataa aaatagcaat ccttattaca atattaaaca
     2641 cttttatttt ggattttaag aggcattttg aagacttaga ggcaaatcat ataggttttg
     2701 tacttaaaaa tctatacagt ctcttaaaac gcaaatatga gccaaataaa tatatgctaa
     2761 tttcacaaac aaaaatttca gcaaaatcag tgactaattt tttagatact gcccatttac
     2821 atgcaaattt aaaaattagc ataaaatact ttaaaacttc cccatgtttt tctaaattcc
     2881 tgcagggctt ttcttatcaa aaacttagaa attttaattt aactctaaaa tctccgtaag
     2941 agcataaggg aaatttgcta tcattcaaaa atgatagatc tggcaaggcc agacattcca
     3001 agggttttaa gttattttaa agtgatatca tacaaagctg tagtgtcaca cttttgtgac
     3061 actacataca gcatttgtca caaaaataag acagcacttt tttacagaaa aacaataaaa
     3121 aagacatcag ttatcactaa tgtcttaaat aataattttg cttttcgaaa ttccaaattg
     3181 cggtaattga atgtgctttt ttcttcgtct gtcgttttat cttcatcact tgtattaatc
     3241 aaattaccat cttcggcatc gtctaagttt aaaattttat gcttttgttt aagcaatcca
     3301 ccataactta acatacgttt tcgatacaaa cctttttcta aatcacttac aatttcttga
     3361 ttttttcgtc gtcatcagtt aaaaagtcag atgatttaac ggaatatttt gatgtctctt
     3421 cgagtgttat aaaatcattt gaattattga ttaaagatat tatattgttt catgttttta
     3481 cggcgcatat aaagggcatg tgtttcttca agttcagtta gaattgtttg cattaaataa
     3541 gcttgcattg acttgattgt ttccttttgg cctttaactc ccctatcatg tatagctttt
     3601 ttaagtcttt taaagaagtt aatatttcat cctcaatgtc ctctaacatg taatgcatat
     3661 cttcatgcct tgaattaaat gatttttttg ctttaagaat aacagccttt atgatttcta
     3721 aatctctata atcatatttt aataaataat tagttagttg ttctgggaat tcttgcaata
     3781 gcatttcttt atcatcaaaa ttatgtgtaa attgatttga atgatttgaa tgattactaa
     3841 tttcattttt gtactttata tcattcaagt cattcatatc attattctca gtatcattaa
     3901 agtcaatgtc attaaagtca gtatcattag tgttcgattt tcgaacttct ggacgttcga
     3961 ttttcgaact tctggacgtt cgattttcga acttctggac gttcgatttt cgaacttcct
     4021 tctcgccgta aggttcaaca tcgttttctt ctttttctat tttgtaaata tcacgttctg
     4081 tgacaatagg tttcattaaa tatagaatat ttggtttatt taaaccacgt cgtttttgaa
     4141 tgagtagacc atcgttttct aacccttttt tatttttgtt aacttttctt ttttacaatt
     4201 taagatttcc attagctttt catttgaata aacaaagtaa atgttaccat cttcatcaac
     4261 ccagctattt ttaatagata aatttaagcg atcacgtaag atagcatagg ctattttcat
     4321 atcattagtt agatttttat aattttcact ggtaaagaat actttaggga tttgataaaa
     4381 tctttctttg taattttctt gcactgtaaa atattgattt tgcatgacaa aaacctcttt
     4441 ccatatttta gtttggtaag aggtaataaa acgtttttat ttagctttac atttatttaa
     4501 tgatttaggt gcttgcacta agatattatt cattatataa tacaagtatc gaaaattata
     4561 taaataaaca gtttctaaac gttttattac caaaccccga ctattaccag tagttggggt
     4621 ttttgttata ttaagtttat tatagcactt taaataaact tataaaaggg aaaatatagc
     4681 tttatcaagg gtttataaac ccttgataaa tatcataaac ctttcataaa cccttgataa
     4741 aaaggttgat ggatgtttat ttttatttat taatcacttt attattaagc attataagct
     4801 tataatattt tatcaagggt ttataaacat tttataaagg gttgatgata tgaaaagtgt
     4861 gaaaaagttg agtgaagaat taggggttag taagcaaacg atttttaata atattaagcg
     4921 attgaatata gagacaataa aacaggaaaa cacttcgttt attaaagaag ataccgatat
     4981 agaaaaaatc attcaaagag taaatgaaaa taaaaagaaa tatggttttg aaagtactac
     5041 tgaagacaaa caaaaaaagg gtcggataat attaattttg aatcgaaaag cgatgctcaa
     5101 atagtagaaa tccttaaaaa tcagattgat actttaaata atcaaattga aaaacaagaa
     5161 agtcgtcatg aaacaacaat tgaattttac agaaaagagt tgcaagaaag atcaaaattg
     5221 cttgaaaatc agcaagttct ggcattagag agtaataaaa agattcaaaa attagaaaat
     5281 caattagaaa aagaaaaaca ccttaattat ccctttgata catctactaa cactagacaa
     5341 aacgttgatg cacaagaaaa aacatatact actaatcctg taaatattaa cagagatcag
     5401 gaagaaacta aagaaacaga gattcaatat aaggatatat ctggaagtca aagcgacgaa
     5461 agtacacaag gtgaagaagc aaaaaagaag acgttccagc taatctaaat gacaatgata
     5521 gtgatataga agaaaagagt gaagaaacgg aacctaaaaa ggggttttgg agtcgtttgt
     5581 ttggtagcta aaataattga ttaggcacta aaagttataa aattttagtg tcttttatat
     5641 agtgagaact tctggtaatc atcgattatg taaactaaag tatttcaaat aattaactgt
     5701 attaatactc tcatcatgat tgcgttataa acgttcgtta ttgagacaaa atttaatagt
     5761 actactacac aaaagagagt gcgaattcgc actctctttt tgtgataaat gaatggttaa
     5821 gaaaataatt catccacagt tgtatcaaac aatcttgcca acttaaatgc taatgtcaat
     5881 gtaggatcat atttattgtt ttctattgca ttaatagttt gcctagacac ttttaattct
     5941 ttacttaaag tttcttgaga aattcctttt gttttctata ttctctaatt ctatttttca
     6001 ttaatttaac ctttagatgt atatttttta tttgtagtat agtaattaaa cagcataaga
     6061 aatagtgcta caattataaa gaaaatttct ggatattgag aaaaccaaga tccttcaata
     6121 cttggtgaca aacctgtaaa tttaagcact agtgtaaata acatacaata tacaatccaa
     6181 ataaaacttt tagccagtat ttcaataaac attttacgtt gtctttcatc gtatcgatct
     6241 tgttgtcctt ttttatctaa tgtttctgaa ggtaaatatt tgttagttat agccgtccat
     6301 aaacaagaaa aaattaaaat aataataaaa ggaattaaat tcattataac acctcataaa
     6361 tgtaaaaagt atttgacatt tatgagtgta aatatttttg atacaaatgt caaatacttt
     6421 ttacattata atatatttta aaacacctta ttagtaaaac aattactata tagaaagctg
     6481 cgaactcgta ctctttttct tgtataatta ttaaaatctc aattcaataa tatgttatgg
     6541 aatttgagac actgtgagag acgctcattt gcattgacaa tcaatttatc aagataatcc
     6601 cttatcatgt ttaattctat aaactgtttg tcttgtgata ttaacttctt tcgcaatctt
     6661 actaatcgct ttgccttctt ctaacatttc caccacgcga tgataaataa cacgtttctg
     6721 tgggtcttta gcatttggtg aataaagtaa agggcgccct ttatatacgc ctttttcctt
     6781 cgcaacttga atcccttgcg cttgtcgacg tttactttca tttctctctt gttctgaaac
     6841 cattgctaat atttgaatga ttaaatcttt cataaactta tccagtaatg gattgccaat
     6901 tacttcattc atcataggta agctggtaat cattaactga acgtcttttt cttttaaata
     6961 attcacagtt tcaataattt catcatagtt acgtcctaaa cgatcaatag attccacaac
     7021 gaatcgatct cccattctga caaaattgag tgcttcttga aatacaggtc tattttccac
     7081 tgactttccc gactgtttct ctgtaaagat tttctccaca ccaaacgtct ttaaattatc
     7141 caattgtctt tctaaatttt gatctatcga tgatactctc gcataaccta taatcattca
     7201 tcttcactcc ataataaata tacaccctaa tcatacgttt taattgttat aatttcaaca
     7261 attctttttg tatggttagg gtgtactcaa agtgtacata tctataatta aaacttacta
     7321 aaaataaata tagatttttt ctttgtaaca gaaccgttca tttgaaggtc atctctatca
     7381 taaatattta aattaactaa aaattttaat catctgttta atacttatga aatgtattta
     7441 cggtaggtat taaaattgat gaaatttata taagtgcttt caatgaaaat gaccgtttat
     7501 ttatcctcct gatttaagga gttagaaatt tcgaaaacga ttctttccat ttgttgcatt
     7561 tgttccatgt ccagatattt aatacattat agaaaaccaa agaccatcac taattaaacg
     7621 cagttttaaa atttcatcag gattgccttc gtctttaaaa tgggcctctt ttaatataag
     7681 ttctactctt tcatacctaa ctctttcaat gccatcgttt catacgccga ttctcctgat
     7741 tccatagcaa actcagcgat aaacattggg aatactgcat tgagttctat tatatgctct
     7801 ttcattcgtg gccatatttc acctccagct ttaccgtatg ctgttataag ttgctctaat
     7861 ccttcgtcgt cgaatacacg atggtgtcct ataaagtcca ttgatgggtc ggagtgggtt
     7921 gcttcagtcc agtctatgag acctgtgacg tttgcttggt tatctaccat tatatgtcct
     7981 ggatgtaagt ccccatgtat catggtcgca tgtcgaggcc atagttcgtc gttttctaac
     8041 cattgtttcc atctgttcca taattcatct gatacgccat aagtttcttt aactttattc
     8101 attcttcttt gaaagtcatt ttttatttct tgtatggttt tgatatttat atgctgaacg
     8161 ttaatgtttt cttctggtat gttgtgtaaa tctacgagtg tttcagctaa tgtgttaata
     8221 aagttttctg gtaatggttt gtgttcaatt tcccatacat aattttgtat ttctggatct
     8281 attgtggctg cgggtttacc tgtaagtttt gggtaagcaa taaggtcttt tgcatgtact
     8341 ttccacttcg gtatttcaaa tgaaacattc ttctgtaaga agtctaccgt ttgtttttcg
     8401 ggttttgttc gtttataaac gtcaggtctt cttggtagtc tcaaaaccca ttctactcca
     8461 tgtttatctt ttccaaatgc aacttgaaaa tcaagtcccg attcattcaa tgagattgtt
     8521 tgaggttgga tgtgtaattg atatttttct gcacatttaa taatttcatt atgtcgagtc
     8581 attttattgg atccttattt ctattatatt tttcttgtga acgtattttt tatattgata
     8641 taaatgaacc taatattcaa tataaattag tgtatagttt ttaagttata tcatgaagag
     8701 attgtcctgt taattcccat tttttatctg atacatgttt aacaaacctt gtatcatgtg
     8761 atgtaaacaa aatgattcca ggatatttat tcataaacat ttctaatgct tctaatgttt
     8821 taatatctaa aaaattagtt ggttcatcca aaattaacat attcgctttc gttgaaaata
     8881 atactgctaa cgataatttc gttctttccc caccactcaa aacattacaa gaacgatcaa
     8941 gtgcttcatt taaacccaag ttatttaaaa tagctctact gaatgattct gatgaatccg
     9001 tttcatccat taaatattgc aataatgaaa cgtcacgcat gtcttcataa gcaagttgac
     9061 gatagtatgc catttgcact ttaggagaac aatcaattcc ctctatttgg tggtaaatag
     9121 cttcaagtaa agttgtctta cctacaccat ttgcacctac gagcgctata tttttgccat
     9181 atggtatttg gaatcgtact tgtgttagca gtttttgact tcctttaacc aatgttagat
     9241 tttgtgcaat gattggataa ttattatgga tatcataaat tttattttgt gggaaattga
     9301 attcatgata actttgtggt ttttcaactt cttccaaatg ttccattctt tttcaatatg
     9361 cttagcttgt ttttgagcag ccttctcaac cgtgcctttt tgttttgatg cacttaaacg
     9421 atctggtgct atacttttgt ttttttgttt tgatgatgct tgtgccattt gttgcgcttg
     9481 atttcgttta gctttactgg cttgggacaa tctttgtttt tcacttatat actgttcata
     9541 ttgacgttgt tgttctaact gttcttgttc atattgattt tgatactgtg tgtaattacc
     9601 tttaaacact cttattgtgc catcttcttg tatatcccaa attgtgtcag caatttggtc
     9661 tataagtgct ctatcatgac ttactataat taaagtacca tagtaatatt ttaaaatatt
     9721 tttcagataa tctttaccaa ttttatccaa gtgatttgta ggttcatcta aaagtaatat
     9781 cggactataa tttgatatga cattagctaa tttatatttt gctttttcac caccactcat
     9841 actgtcggtt gtatgcatag gtatatggag ttcactcatt aaactaccgt ctaacgtgtt
     9901 aaaatcattt tccacatcca tgttaagctg ttcaaaatat tgaatttcgc caaccgtttc
     9961 aactgttcca gattctggtt ttgtttttga gcaatcatat ttagtaatgt ggttttgcca
    10021 gtaccattac ccccaataag tgctattttt tcaaattggt aagcgtaaag atgaccgatg
    10081 ttaagtgatc gtaaatctgt caatttatga ttgatttggt taaatttaat tgtatattgt
    10141 tccatattta tacactcctt gtatatttaa aggacgtgta cgcaaaaaat gagacaggct
    10201 actcccgtct cattcacatt acactttcaa acacttaaaa atttattatg atgttttagt
    10261 atttgaaagc gtttattatt cctatcgaag gataaaaaat gacataagtc atcctatgag
    10321 tgtgtattgc ggacaagcct ttttgaatta atttagtttt gtattcaaaa aggtttattt
    10381 gagtctcata gaagctgtca ttttaatcct ccttcatcga taaaatagta atgttaatat
    10441 aacattttgt tggtttttta caatatatct ctaagtagaa agattatata acaaaagtat
    10501 aaaaatacaa ttttagattg attatacatc tccttaattt agagtgtact cataaaatac
    10561 ggttctgttg caaagttgaa tttataatat aattttaaca aaaggagtct tctgtatgaa
    10621 ctatttcaga tataaacaat ttaacaagga tgttatcact gtagccgttg gctactatct
    10681 aagatatgca ttgagctatc gtgatatatc tgaaatatta agagaacgtg gtgtaaacgt
    10741 tcatcattca acgatctacc gttgggttca agaatatgcc ccaattttat atcaaatttg
    10801 gaagaaaaag cataaaaaag cttattacaa atggcgtatt gatgagacgt atatcaaaat
    10861 aaaaggaaaa tggagctatt tatatcgtgc cattgataca gagggacata cattagatat
    10921 ttggttgcgt aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa
    10981 acaatttggt aagcctcaaa aggtagttac agatcaggca ccttcaacga aggcagcaat
    11041 ggctaaaata attaaagctt ttaaacttaa acctgactgt cattgtacat cgaaatatct
    11101 gaataacctc attgagcaag atcaccgtca tattaaagta agaaagacaa gatatcaaag
    11161 tatcaatacg gcaaagaata ctttaaaagg tattgaatgt atttacgctc tatataaaaa
    11221 gaaccgtagg tctcttcaga tctacggatt ttccccatgc cacgaaatta gcatcatgct
    11281 agcaagttaa acgaacactg acatgatata ttagtgatta gctatatttt ttactttgca
    11341 acagaaccag cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct
    11401 tgaacccaac ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca
    11461 gatatatcac gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca
    11521 tccttgttaa attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat
    11581 tatactataa attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt
    11641 attaatacaa agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac
    11701 tataggattc aacattatat taatcgtttc tttaataatg attatcttct tattttttat
    11761 aaatcgtagt aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga
    11821 ataaattaga aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac
    11881 ttttatattt caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa
    11941 ctatactaat attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt
    12001 aaaacgttca ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt
    12061 ttcttgtgtt attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc
    12121 agaacgtctc ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat
    12181 aaaattattt agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc
    12241 tcttttgcct ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc
    12301 tctgcaattg ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct
    12361 tgtttattta atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga
    12421 ccggctgatg atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa
    12481 tgaaataata attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta
    12541 tgaaaactca cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc
    12601 cgtcctagtc tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt
    12661 gctttatcta aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt
    12721 tcacaaccat atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa
    12781 actcttgcat aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata
    12841 acttgattac gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt
    12901 ctatgtaata cttacttatt tagacaaaaa acaagagtgt acagaaaatg gttgttttct
    12961 ggacactctc atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga
    13021 gtcaagtatg gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa
    13081 tatcatttaa aatgtctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg
    13141 caaaattcag cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag
    13201 cagttttcat tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg
    13261 atttgtatcg ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt
    13321 tatcactaac ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt
    13381 ttttatccca tattatattc ataacatccc attcagccat agatatttca acttgcttat
    13441 tggtcattta aaacacccat tccttttaat attttttcac ttattaattc agcatttttc
    13501 ccagacgggt ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt
    13561 acgtaaccta caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc
    13621 ccatacagtt catacttttc atttttctta atcaataatg aagaagataa ttgattcttt
    13681 gcttttttac taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca
    13741 agattagata ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca
    13801 ttaccataat ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta
    13861 atacgttcga agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta
    13921 ttccaagact cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt
    13981 ataatatgac ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa
    14041 tatctttttc tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac
    14101 ataacgaaag atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg
    14161 ctttgtaagg gctttttata attataatca gttaaggatt gccccattaa aaactggctt
    14221 tgaattatca tgataaaaaa gtaaaaatac aaataaaaat tagaattaat tttgactgct
    14281 ttttcagatc ggcttctttt atattaatta atctactttt gagtaatgat tttttaccat
    14341 taaatgaatg gcttaatata tttttgttgg aaaatggggt ttttaatacg gagtccataa
    14401 tagattccgc ataagtttta aattcatttt tgttaatatt attaaggaca aatctatcgg
    14461 cttctacttc attgtcatga attatctttc tttttacaat atgtactaat ggattgtaac
    14521 tcataataat agagaagata ttaaagataa ttaaatgtaa agtatctcta tttttagcat
    14581 gagcatattc atgcagtatt atatatttta gtcttttatc aattacactt ttaaaatatg
    14641 aactaggaat caaaataata tatttcccat accaaaaagt tattggagat tgaatagcct
    14701 ctgcttttcg aatcacaata ttttttatat tgatggttga aaagtatcgt atctatttta
    14761 ttttttcatt ttcgtttaga taaagtgact gtttctttaa atatttaaga tataataagg
    14821 ctttcaaaaa tttaaaactt aaaataataa ctaaaactat ccaaataact gtgcagatat
    14881 tatcaattga atcccaatta aacttatgga tatctgttgt gaactcttga ataggtttgg
    14941 tggtatttat gttatggttc aaatcgtgtg acttactttc aactgtgggc gcttgattat
    15001 tcacattatt aaattttata aaagagaatt taattgggat aaaaggaatt aatccagcaa
    15061 gcatagttag ataccaaact ttataattta aactataatt aaaatagcgt tttaatatgt
    15121 acctaaaaaa tactaacaat agaaatataa aacaaaagct tactacgctc attattagta
    15181 atttagccat tttgacacct tctttcaaat atttataata aacaattgac atcaatatta
    15241 caattgtaat attattgatt tataaaaatt acaactgtaa tatcggaggg tttattttga
    15301 aaaagttaat atttttaatt gtaattgctt tagttttaag tgcatgtaat tcaaacagtt
    15361 cacatgccaa agagttaaat gatttagaaa aaaatataat gctcatattg gtgtttatgc
    15421 tttaaatact aaaagtggta aggaagtaaa atttaattca gataagagat ttgcctatgc
    15481 ttcgacttca aaagcgataa atagtgctat tttgttagaa caagtacctt ataataagtt
    15541 aaataaaaaa gtacatatta acaaagatga tatagttgct tattctccta ttttagaaaa
    15601 atatgtagga aaagatatca ctttaaaaga acttattgag gcttcaatga catatagtga
    15661 taatacagca aacaataaaa ttataaaaga aatcggtgga atcaaaaaag ttaaacaacg
    15721 tctaaaagaa ctaggagata aagtaacaaa tccagttaga tatgagatag aattaaatta
    15781 ctattcacca aagagcaaaa aagatacttc aacgcctgct gctttcggca agactttaaa
    15841 taaacttatc gcaaatggaa aattaagcaa aaaaataaaa atttcttact tgatttaatg
    15901 tttaataata aaaacggaga cactttaatt aaagatggtg ttccaaaaga ctataaggtt
    15961 gctgataaaa gtggtcaagc aataacatat gcttctagaa atgatgttgc ttttgtttat
    16021 cctaagggcc aatctgaacc tattgtttta gtcattttta cgaataaaga caataaaagt
    16081 gataagccaa atgataagtt gataagtgaa accgccaaga gtgtaatgaa ggaattttaa
    16141 tattctaaat gcataataaa tactgataac atcttatagt ttgtattata ttttgtatta
    16201 tcgttgacat gtataatttt gatatcaaaa actgattttc cctttattat tttcgagatt
    16261 tattttctta attctcttta acaaactaga aatattgtat atacaaaaaa tcataaataa
    16321 tagatgaata gtttaattat aggtgttcat caatcgaaaa agcaacgtat cttatttaaa
    16381 gtgcgttgct tttttctcat ttataaggtt aaataattct catatatcaa gcaaagtgac
    16441 aatagcattt tacaagtatt ttttattgtt cgattagggt aaacctaaat aatacataaa
    16501 ttatattaca atatgtttat tatagaggct aaagtatctt agaaatttgg atagtaggtt
    16561 tttcgggaat aaaagtatag ttggctttaa tatataatta agctaagcta tcatttatat
    16621 ttactcgatt ataattcgca cttcaacttt tttataacgt aaaaattaaa acgtagtttt
    16681 atttatcttt agtaatatct ttttaaacac tacagtttct tcattagtta aattagcgaa
    16741 gtaatgatta ttaagttgat aggctttctt ttctaatgtt ggccataagt cttttgcttt
    16801 atttgtactg tttattagca cagttcttct attttcatta tcagtttgac gtgttattag
    16861 atcctttttg gacatcttat ctaatattcc agatattgtt gaaggttcta aatttaaagt
    16921 attaccaatc gctttaggtg tattcaaatt actattaatc aagcaattca aaacaccata
    16981 ttctgctgga gtaatattat agggacttaa taaactttta aaatgtttaa aaactctatt
    17041 ctgagaagta ctcaacaaat aatttataca attatctaat tccacaacta aaacctctct
    17101 taaatcatta gtattgactc gcttatcata tcatgataag ttttgtagga aaatagtttt
    17161 gcaacaaaaa catacttcta caaaacaatt gtgaaagaag gctaataaat gttcaatgcg
    17221 gtagtagtga gaaaaagtgc atcaaatgtt agttataaag tagaaaaagt tgatgaatct
    17281 catttatcga agggtgatgt attagtaaaa gtggtatact cttcaataaa ttataaggat
    17341 atgctagctt tacaatataa aggcggtgta attagagatt atcctatgat tcctggtata
    17401 gattttgcag gtattgttga atcaagttcg aatgataagt ttaaagaagg cgataatgta
    17461 ttagttactg gttatgatgt tggcgtgaca catacaggtg gattttcaga atatgcacaa
    17521 gtgcctggag agtggattgt tcctattccc caagaaatgt ctattaaaga gtctatggta
    17581 tatggcacag ccggttttac ggcagcatta tcaatttttg aactagaaaa atatggaatg
    17641 aatatcaaat cacaacctga aattttagtg tctggggcta caggtggtgt gggcagtgtt
    17701 gctatacaaa ttttacataa aattggatat gaaaatatca ctgctatcgt aagaaaagaa
    17761 aagcaaatag aaatcgcaaa aaaattaggt gcaaaacaag taataataat tgaagatgat
    17821 aataaaccgc ttaaaaaagg tatttttgat tatttcttag atacagtggg gagtaatgta
    17881 acattatacg gtttaaaacg tctaaattat caaggtgttg ctactgtatg tggaaatgta
    17941 gcaggaaatt cacttaacgc taatatatta ccgtttattc ttagaggtat taaattaatt
    18001 ggcattgatt ctgtatatgt tgatcataat atccgtgaag atatatggag taagttagca
    18061 aatgaatgga atataggaaa ttcacttcta tacaatgaaa ttggatttga agaattctat
    18121 aaaacgatag atcagctttt aaaaggacaa catttaggaa gaactatttt aaaagtataa
    18181 gtgtgagtat tcattaatac atttactatt aattcaatca ttttgcattt ctctactaac
    18241 cagtgttata atttatataa cgaaaatgat taacaattaa tgcaccaatc cccacactat
    18301 tgcagtagtg tggggatttt ttcgatgctg gcttataaag tcgcctatta attatttgtt
    18361 gcgtttacta agccaataag tataatacgc aacagcacag ccactgatga ctggtgctat
    18421 gatgtgaacg aaaatgatta gcaaagtaat gcacctcctc tcttcgtcaa ttgacgcctg
    18481 agagataggc gactctatta ttataccatc tgtgaatata caagcatatc tacttccgat
    18541 aagtcgtctt atgttatata actttgtttt ttatagtatc aagacaagaa gaaactcgtt
    18601 tcaaaaaccc tcatgatttt tagagaaaaa ctctcttatt tcatcgtctt taataaaata
    18661 atatgccatc tttccatctt tataaaaatc aagtacctca tttttatata aaagccttaa
    18721 atgatgtgaa gttgaagcaa cactcatttt caatatcaaa gaaatatcac aaacacacaa
    18781 ctcatcttct ttaatcaaag ataatatgat tttcaatttc ttctcatcac aaattttttc
    18841 taaaatgtta agtaatttct tagatttatc atcttctaaa aaacttaaag cattgttaac
    18901 tttatcctca tgtacacaga tcacatcaca agtattttca taactcatat aaaatcacac
    18961 cctaaattaa aatataaatc ctaaaattgt ttgaatagtg tcattttcaa taataataaa
    19021 taaacctaaa gctatataaa taatagccat aatccaacga ctaaatttct caacaatttc
    19081 tccaattcct ggaatattag ctaatttttg tgcagtaaac accaagaaga aaattaaaat
    19141 taaaaagaca aacagagtaa gtaataaatt agtaacactt aatgtcacaa aatacggaac
    19201 aaataaacca atattatcgg cgccacaact tgctatcgta acaattgcaa ccgtaccaac
    19261 taatttagac aatccttttt cattcaattc tttttagctc tcttttctcc ttcacaatca
    19321 tcataaatag ccactttaat tccaagataa attggtatta aacccaataa acctaatatc
    19381 cacttttctg gaacataatt taatacaaaa gctaaa
//
