LOCUS       CP127776               20730 bp    DNA     circular BCT 19-JUN-2023
DEFINITION  Staphylococcus aureus strain C80 plasmid pC80_1, complete sequence.
ACCESSION   CP127776
VERSION     CP127776.1
DBLINK      BioProject: PRJNA914892
            BioSample: SAMN32360835
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Hybrid Oxford Nanopore Technologies Illumina Sequences of 174
            Staphylococcus Aureus Isolates from Chronic Rhinosinusitis Patients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUN-2023) Department of ENT Surgery at the Basil
            Hetzel Institute, Adelaide Medical School, The University of
            Adelaide, 37 Woodville Road, Woodville South, SA 5011, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-NOV-2022
            Assembly Method :: Flye for Genome, plassembler (Unicycler) for
            plasmids v. 2.9.1 (Flye) with short read polishing, 0.1.1
            (plassembler) with 0.5.0 (Unicycler)
            Assembly Name                     :: C80
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 33x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/12/2023 14:55:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,750
            CDSs (total)                      :: 2,668
            Genes (coding)                    :: 2,596
            CDSs (with protein)               :: 2,596
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 47 of 72
            Pseudo Genes (incomplete)         :: 24 of 72
            Pseudo Genes (internal stop)      :: 11 of 72
            Pseudo Genes (multiple problems)  :: 9 of 72
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="C80"
                     /isolation_source="Patient Sinus Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pC80_1"
                     /geo_loc_name="Australia: Adelaide"
                     /lat_lon="34.9285 S 138.6007 E"
                     /collection_date="2012-05-09"
                     /collected_by="ENT Surgery Department at the Queen
                     Elizabeth Hospital, Adelaide, Australia 36"
     gene            166..441
                     /locus_tag="PCM63_13625"
     CDS             166..441
                     /locus_tag="PCM63_13625"
                     /inference="COORDINATES: protein motif:HMM:NF018653.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WJC79350.1"
                     /translation="MSIKLYNINEEYREKFYQIPKVFFTNTKYIKLSNDAKMAWGILRD
                     RLDLSIKNGWVDSKTGNIYFYYKNENPQNILNCKKDKVIKIKKELN"
                     /name="replication initiator protein A"
     gene            853..1135
                     /locus_tag="PCM63_13630"
                     /pseudo=""
     CDS             853..1135
                     /locus_tag="PCM63_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2346..2963
                     /gene="cadD"
                     /locus_tag="PCM63_13635"
     ARG             2347..2960
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2982..3329
                     /locus_tag="PCM63_13640"
     CDS             2982..3329
                     /locus_tag="PCM63_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WJC79352.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3498..3590
                     /locus_tag="PCM63_13645"
     CDS             3498..3590
                     /locus_tag="PCM63_13645"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJC79353.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3802..4368
                     /locus_tag="PCM63_13650"
     CDS             3802..4368
                     /locus_tag="PCM63_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WJC79354.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKIKKIGCYTKRFRYI"
                     /name="DUF4062 domain-containing protein"
     gene            4373..4777
                     /locus_tag="PCM63_13655"
     CDS             4373..4777
                     /locus_tag="PCM63_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJC79355.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIK
                     GLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="hypothetical protein"
     gene            complement(4897..5712)
                     /locus_tag="PCM63_13660"
     CDS             complement(4897..5712)
                     /locus_tag="PCM63_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WJC79356.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5705..7148)
                     /locus_tag="PCM63_13665"
                     /pseudo=""
     CDS             complement(5705..7148)
                     /locus_tag="PCM63_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(7120..7713)
                     /locus_tag="PCM63_13670"
     CDS             complement(7120..7713)
                     /locus_tag="PCM63_13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WJC79357.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7977..8357)
                     /gene="blaI"
                     /locus_tag="PCM63_13675"
     ARG             complement(7981..8357)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8347..10104)
                     /gene="blaR1"
                     /locus_tag="PCM63_13680"
     ARG             complement(8351..10104)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10211..11056
                     /gene="blaZ"
                     /locus_tag="PCM63_13685"
     ARG             10212..11053
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11425..12033
                     /locus_tag="PCM63_13690"
     CDS             11425..12033
                     /locus_tag="PCM63_13690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WJC79361.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGESIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12447..12740
                     /locus_tag="PCM63_13695"
     CDS             12447..12740
                     /locus_tag="PCM63_13695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WJC79340.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12815..14749
                     /locus_tag="PCM63_13700"
     CDS             12815..14749
                     /locus_tag="PCM63_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WJC79341.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14753..15064
                     /locus_tag="PCM63_13705"
     CDS             14753..15064
                     /locus_tag="PCM63_13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WJC79342.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15076..15702
                     /locus_tag="PCM63_13710"
     CDS             15076..15702
                     /locus_tag="PCM63_13710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WJC79343.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15940..16568
                     /gene="mobV"
                     /locus_tag="PCM63_13715"
                     /pseudo=""
     CDS             15940..16568
                     /gene="mobV"
                     /locus_tag="PCM63_13715"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006310 - DNA recombination
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16608..17207
                     /locus_tag="PCM63_13720"
     CDS             16608..17207
                     /locus_tag="PCM63_13720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WJC79344.1"
                     /translation="MIQNYQKSLDTLKKLLSVMYEIKTKNVGGWFHKEKQETGNIVITK
                     TDFEKYTKQIKAAQMILDDYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFND
                     LAQRYNYLLSENEKKDKELNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIR
                     EVMTIDNNDEQFFKKKYQAQEREIIFKEDREDGYTL"
                     /name="recombinase"
     gene            complement(17249..17533)
                     /locus_tag="PCM63_13725"
     CDS             complement(17249..17533)
                     /locus_tag="PCM63_13725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJC79345.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEKAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            17591..18451
                     /locus_tag="PCM63_13730"
     CDS             17591..18451
                     /locus_tag="PCM63_13730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WJC79346.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18538..18879
                     /locus_tag="PCM63_13735"
     CDS             18538..18879
                     /locus_tag="PCM63_13735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WJC79347.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19118..19189)
                     /locus_tag="PCM63_13740"
     CDS             complement(19118..19189)
                     /locus_tag="PCM63_13740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJC79362.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19338..19523
                     /locus_tag="PCM63_13745"
     CDS             19338..19523
                     /locus_tag="PCM63_13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJC79348.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19742..20485)
                     /locus_tag="PCM63_13750"
     CDS             complement(19742..20485)
                     /locus_tag="PCM63_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WJC79349.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10212..11056
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7447..17740
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17592..18451
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19743..20485)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatactaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atactgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttagacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1621 aaaataaggg cataaaaaat aaaagccccc ccagataaag tgaggtagct ttttctttcg
     1681 acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc
     1741 aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa
     1801 gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg
     1861 tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat
     1921 tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga
     1981 accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct
     2041 aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct
     2101 ccatgtctac gcatagacac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac
     2161 ccttaactaa acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga
     2221 caagttttgg gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag
     2281 cacctatgat tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt
     2341 gtattatgat tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt
     2401 tattagtaat tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata
     2461 tttatgttgg tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt
     2521 ttgtattaaa ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt
     2581 atcttggaat taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaag
     2641 aattgaatga aaaaggattg tctaaattag ttggtacggt tgcaattgtt acgatagcaa
     2701 gttgtggcgc cgataatatt ggtttatttg ttccgtattt tgtgacatta agtgttacta
     2761 atttattact tactctgttt gtctttttaa ttttaatttt cttcttggtg tttactgcac
     2821 aaaaattagc taatatccca ggaattggag aaattgttga gaaatttagt cgttggatta
     2881 tggctatcat ttatatagct ttaggtttat ttattattat tgaaaatgac actattcaaa
     2941 caattttagg atttatattt taatttaggg tgtgatttta tatgagttat gaaaatactt
     3001 gtgatgtgat ctgtgtacat gaggataaag ttaacaatgc tttaagtttt ttagaagatg
     3061 ataaatctaa gaaattactt aacattttag aaaaaatttg tgatgagaag aaattgaaaa
     3121 tcatattatc tttgattaaa gaagatgagt tgtgtgtttg tgatatttct ttgatattga
     3181 aaatgagtgt tgcttcaact tcacatcatt taaggctttt atataaaaat gaggtacttg
     3241 atttttataa agatggaaag atggcatatt attttattaa agacgatgaa ataagagagt
     3301 ttttctctaa aaatcaggag ggtttttgaa acgagtgaaa cgagtttctt cttgtcttga
     3361 tactataaaa aacaaagtta tataacataa gacgacttat cggaagttat ctatcatcgt
     3421 atattcggag atgatataat atacaggtcg cctatctctc aggcgtcaat tcagacgcag
     3481 agaggaggtg cattactttg ctaatcattt tcgttcacat catagcacca gtcatcagtg
     3541 gctgtgctgt tgcgtattat acttattggc ttagtaaacg caacaaataa ttaataggcg
     3601 actttataag ccagcatcga aaaaatcccc acactattgc agtagtgtgg ggattggtgc
     3661 attaattgtt aatcattttc gttatctaga ttataacact ggttagtaga ggaatgcaaa
     3721 aagataatat tttaagtagt ctttttggat attatcatat gatatattta tgtaaattga
     3781 ttttttatta aaggagcata tatgagtaat actaaaatta aatatcaaat ttttatttca
     3841 tcaacttatt tagatttaat agaagagcgt caagcagtag tagaagcagt tttaaacagt
     3901 aataatattc cagcaggtat ggaacttttt aactcaagta gtaaaagcca atgggaaata
     3961 ataacacaat ggatcaatga atcagatgca gtgatattat tgttaggttc tagttatgga
     4021 acaattgata gtgaagaaaa tattagctat acagaaatgg agtacaattt tgctaaatct
     4081 ttaggtaaac ctatatatgt ttttgagatg aataaagcat ctaccgaatc cgcggaaaag
     4141 tctaaaaaat tagatgagtt taagacaaaa gttaaagaaa atagactaat tagtccaaat
     4201 attaatgata tttcggaatt aaaaagtaaa gtatctcaga ctttaatgca aagtgtacct
     4261 agtgaaatta aagaaaatag tggatggata agagtacagg attgtggtaa aaatgtaaaa
     4321 aaaattaaaa aaattggatg ctatacaaag agatttagat acatatgatt ttttgaaaga
     4381 agaactttat aaaatattca tgtatgtaaa aactttttat ttccagcaca caccatttga
     4441 tgatagttat attgaagata tagaaaacta cctgctaaat tatgaaaata atccacataa
     4501 atcattcatg aaaataaaag tttatgatta taaaaacttt ttaaaacatt taaaaaacat
     4561 attgatttta attaaacaag gaaaaaagcc attagctcaa gccggtcatt ttaaattaag
     4621 cttttacgaa gaggatttaa aattgttaca aaaaaattat aagactacgc tagtcgatat
     4681 taaaggattg aataaacatt tttataagga atgtgatagg tgcttaaaag catataatat
     4741 ttttattgag ggtataaata aacatttata tgaatgatat aagtacaccc taatcataca
     4801 tatataattg ttgtcacttt actcgatata tgagaatgac tttacctaat aaatgagaaa
     4861 agcaacgcac tatattaaaa tgcgttgctt tttctattat cgaataccta taactaaact
     4921 atctctagct gtttctacaa cttctgtact tattttatct aaaccattta tatccataat
     4981 tctgtctatc tgcgcaaata aacgatgaat cagcctaaaa ttcccttttg taattttaat
     5041 aatcgtcgtt attgcctcat aatcagtaaa gtcttcgagt tttaaatcaa atcctaagtc
     5101 ttgccactta tattctaata tatgatgcgt ctcatcttta cttagattat caaattcatg
     5161 cgcaaaacct atacgcgaat atagttgagg ataacgagat agttttttct ctatacccgg
     5221 cataccaata aatatcattg ctaaattatg ttcatcataa atagctctta attgctctaa
     5281 atgttgcact ttaaggcgat caatctcatc tactataatt aaatcaatat atttaaacat
     5341 atcactataa tgtttactat gttcatgtcc atacttattt acaacatgta atttttgacc
     5401 caaatcaatg attgcagtaa tactatataa atcattcctt aatttagttt gtttttctgc
     5461 tggtgcatta taaaatattt tatccaccga tagtatgtca tcggtcgttt tactagctaa
     5521 atcttcccaa cctctatggt taacttgttt ttcaatagta tcccaatttg tgtaatacct
     5581 agacgataaa gtttttccga caccaggttg accataacat ataccaatat actgatattt
     5641 aatacaagca tcacaaaatt cagcaaagcg tttatactct ttcgtttcaa tgaaattttg
     5701 atttttagtc attacgatat ctctttaatt ttttgacgtt tttagtcgtt tcttgaggtg
     5761 aataaccaca ttttttttct tccttaatta attccgtggt acttggacta gcaatatttt
     5821 gttttaagtg ttttcttctc tgactacgag cgtgctgtat gtcttttata tctatggagt
     5881 aatcagctat ttctggacat atagcagtac aaagaaattc atctctataa aacacacgta
     5941 tttcagccat atcatttggg ttataacgaa tcagtacata ttcacctaca taagcttcta
     6001 gattagtatt actgtatcga aaaccttgaa aatgaatgcc atctgaatga acttttctag
     6061 atttaggtat ttccaacaat aataaatcaa gttgttctaa gctacttggc atattaggga
     6121 aaaagtgatt actattccaa tgactgatag gcgtggtatg aatagtacta tgttcttttt
     6181 gattataatc ttcaattaaa aagtaacgta atttttcttc aaaattgtga aaatttatta
     6241 gattactagg agtatcatta ttgtttatat atccaggcag ttgttctaag aaagtttgat
     6301 taactgtctg aaagaatcgt tctatttttc cacgaccacg aggaacacca actttcgaaa
     6361 acatcaagtt aattttcaaa tcaatagcga cttgttccat atgatgtgaa gtaaagtcac
     6421 ttccatgatc tgtgtagaat ttttcgggta taccacacac tggccaattg gtatcatttt
     6481 tattccatat tgcttggtgt agtgttaatg ctgtgttttg agcattgggg ggcatcaaaa
     6541 cttaagaaat agcctgcaat tgcacgacta tagtcatcca taataatagt tagccatggt
     6601 ctattgatat tacctttttg gtctaatata aagatatcta gcaaagtatg gtctgcttgc
     6661 catatttcat tgggtctcga ggattctcta atttgtatta aatcgtactt attttgatag
     6721 tatttttcac cctgatgaga gaaatcaata acagacttag gcatcgcttt aataacacta
     6781 taaatttgtt tataacttgg tatatcaaaa ttattttctt tacagtaatt agtgattttc
     6841 ctatgaattg tggctatact atttctttta ttcataagcg caaggcgttc aatttcatca
     6901 attatctttg gttctatttt acgtgttcct ttatcagctc ttgtcgcata gattagtcct
     6961 ttaagtcctt gttctttata tgacttattc cacctataaa gggtgcttaa cgcaatccct
     7021 ttacttttag aaatacttga taaagattgt tcgcctagga taaaaggttt tataatattg
     7081 tacttttgag tagctttttt acgtttggct tcagaaaaat tagttagata cttctccttg
     7141 tttttcatct tccttgtcct ccaatttatt gaggtaacga taaattgttg tacgtgaaac
     7201 atgccactgt tctgcaattg tcttaattgg cgtgccatta tcataaaggg tcttaagtaa
     7261 gtttaaatct ttttgattta atttttctgg tctgcctcca tatcggcctc tagcacgtgc
     7321 tgcaattcgg ccagctgaag aacgctctaa aattaaatta cgttcaaatt ctgcaaatgc
     7381 tgcgaataaa tgaaataata attgtccagt tgaacttgat ttatccattg ttatattttc
     7441 ttctaaacta tggaaactta cacctcgttc gttaagctca ttaactaatg tgattaaatc
     7501 ctccatatta cgtcccaatc tatctaatct ccaaacaaca atcgtatctc ctgacctcgc
     7561 aaattcaatt gctttatcta aaccaggtct tttacttttt gaaccactca tatggtcatt
     7621 aaatatcttt tcacaaccat atgtatttaa tcgatcctcc tgtaaattta aattttgtaa
     7681 tccagttgaa actcttgcat aacctatttt caaaatacaa acctcctata tacatcttca
     7741 atgtaccata acttaattac aaggtctttt atgaacatag attttttgtt gggtttttga
     7801 acacataatc ctatgtaatt cttacttatt tagacataaa agaagagtgt acagaaaatg
     7861 gttattttct gtacactctc atctttaata atatatttta aatgtcatta acaaaactaa
     7921 tttaataaga gtcaagcata gtttacatat gtattatgtt tgaaacatac ctctaattac
     7981 tttttactaa tatcatttaa aatatctcgc aattcttcaa tttctttgtt atttaattct
     8041 tcatttttcg caaaattcaa cactaaactt ttcatatccc ctccatacag tttattaaga
     8101 aaggttttag cagttttcat tttaatatcg tcttctttaa tatttgatga gtaaaaataa
     8161 atattttctg atttgtatcg ttttataatc tcttttttat atagtcttgt gattaatgtt
     8221 ctaatcgttt tatcactaac ttctttatat ttttgaattt caactacaat ttcattagct
     8281 gatactgatt ttttatccca tattatattc ataacatccc attcagccat agatatttca
     8341 acttgcttat tggccattta aaacacccat tccttttaat attttttcac ttattaattc
     8401 agcatttttc ccagacgggt ttccatctga taaatgtgta gcaaaataat acttatcatg
     8461 atttgtaatt acgtaaccta caaaccaccc attattatac ttcccgttta ctatacctgt
     8521 acctgttttc ccatacagtt catacttttc atttttctta atcaataatg aagaagataa
     8581 ttgattcttt gcttttttac taaaatggtt attttgttcc atcatatttt taaaaactat
     8641 tacttgttca agattagata ttttcaaact atcttccatc caatagcttt tataacttcc
     8701 caaattttca ttaccataat ttaattgctt gagttgagcc gcagtatagt tctttggtat
     8761 ttgattacta atacgttcga agtaccaatt aactgaattt tgcattgctg tatttaaatc
     8821 ttgttcctta ttccaagact cgaaaagata atgtttatga ttccatgaca tacgtgaatt
     8881 tttatcactt ataatatgac ggtcaagtcc aaacagtgct aaataaattt tgtaagttga
     8941 atcaggagaa tatctttttc tactttcttt ttcattataa atatagtatt tgtctttctt
     9001 catgctgtac ataacgaaag atccactatt tgaaccaaaa tttttacttt catctaaaat
     9061 ttggtaatcg ctttgtaagg gctttttata attataatca gttaaggatt gccccattaa
     9121 aaactggctt tgaattatca tgataaaaaa agtaaaaata caaataaaaa ttagaattaa
     9181 ttttgactgc tttttcagat cggcttcttt tatattaatt aatctatttt tgagtaatga
     9241 ttttttacca ttaaatgaat ggcttaatat atttttgttg aaaaatgagg tttttaatac
     9301 ggagtccata atagattccg cataagtttt aaattcattt ttgttaatat tattaaggac
     9361 aaatctatcg gcttctactt cattgtcatg aattatcttt ctttttacaa tatgtactaa
     9421 tggattgtaa ctcataataa tagagaagat attaaagata attaaatgta aagtatctct
     9481 atttttagca tgagcatatt catgcagtat tatatatttt agtcttttat caattacact
     9541 tttaaaatat gaactaggaa tcaaaataat atatttccca taccaaaaag ttattggaga
     9601 ttgaatagcc tctgcttttc gaatcacaat atttttttta tattgatggt tgaaaagtat
     9661 cgtatctatt ttattttttt cattttcgtt tagataaagt gactgtttct ttaaatattt
     9721 aagatataat aaggctttca aaaatttaaa acttaaaata ataactaaaa ctatccaaat
     9781 aactgtgcag atattatcaa ttgaatccca attaaactta tggatatctg ttgcgaactc
     9841 ttgaacaggt ttggtggtaa ttatgttatg gttcaagtcg tgtgacttac tttcaactgt
     9901 gggcgcttga ttattcacat tattaaattt tataaaagag aatttaattg ggataaaagg
     9961 aattaatcca gcaagcacag ttagatacca aactttataa tttaaactat aattaaaata
    10021 gcgttttaat atgtacctaa aaaatactaa caatagaaat ataaaacaaa agcttactac
    10081 actcattatt agtaatttag ccatttttac accttctttc aaatatttat aataaacaat
    10141 tgacatcaat attacaattg taatattatt gttttgtaaa aattacaact gtaatatcgg
    10201 agggtttatt ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg
    10261 taattcaaac agttcacatg ccaaagagtt aaatgattta gaaaaaaaat ataatgctca
    10321 tattggtgtt tatgctttag atactaaaag tggtaaggaa gtaaaattta attcagataa
    10381 gagatttgcc tatgcttcga cttcaaaagc gataaatagt gctattttgt tagaacaagt
    10441 accttataat aagttaaata aaaaagtaca tattaacaaa gatgatatag ttgcttattc
    10501 tcctatttta gaaaaatatg taggaaaaga catcacttta aaagaactta ttgaggcttc
    10561 aatgacatat agtgataata cagcaaacaa taaaattata aaagaaatcg gtggaatcaa
    10621 aaaagttaaa caacgtctaa aagaactagg agataaagta acaaatccag ttagatatga
    10681 gatagaatta aattactatt cgccaaagag caaaaaagat acttcaacgc ctgctgcttt
    10741 cggcaagact ttaaataaac ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt
    10801 cttacttgat ttaatgttta ataataaaaa cggagacact ttaattaaag atggtgttcc
    10861 aaaagactat aaggttgctg ataaaagtgg tcaagcaata acatatgctt ctagaaatga
    10921 tgttgctttt gtttatccta agggccaatc tgaacctatt gttttagtca tttttacgaa
    10981 taaagacaat aaaagtgata agccaaatga taagttgata agtgaaaccg ccaagagtgt
    11041 aatgaaggaa ttttaatatt ctaaatgcat aataaatact gataacatct tatagtttgt
    11101 attatatttt ctattatcgt tgacatgtat aattttgata tcaaaacctg attttccctt
    11161 tattattttc gagatttatt ttcttaattc tctttaacaa actagaaata ttgtatatac
    11221 aaaaaatcat aaataataga tgaatagttt aattataggt gttcatcaat cgaaaaagca
    11281 acgtatctta tttaaagtgc gttgcttttt tctcatttat aaggttaaat aattctcata
    11341 tatcaagcaa agtgacataa ttgttgaatt tatagtaact gaaacgtatg attagggtgt
    11401 atattaatta tgagatggaa atcaatgatt gttggctatg cgagagtatc atcgaacgat
    11461 caaaatttag aaagacaact tgaaaattta aagacgtttt gtgctgaaaa aatatttaca
    11521 gaaaaacagt ctggggaatc tattgaaaat agaccagtac ttcaagaagc acttaacttt
    11581 ttgaggatgg gagatcggtt tgtagtagaa tccattgatt gtttaggtcg taattatgat
    11641 gaagtgattc ataccgttaa ttatttaaaa gacaaagaag tacaattaat gattactagc
    11701 ttacctatga tgaatgaagt ggttggcaat ccattactgg ataagtttat gaaagattta
    11761 attattcaaa tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa
    11821 gcgcaaggaa ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc cttactttat
    11881 tcaccaaatg ctaaagatcc acagaaacgt attatttatc atcgcgttgt agaaatgtta
    11941 gaagaaggcc aatcaattag taaaattgcg aaagaagtaa atataacaag gcagacgatt
    12001 tacagaatta aaaacgataa tgatttgatt taataaactt tgtttcaatg caactgagag
    12061 cttctcacag cgtctcaaaa cagatgatta taatctatta tgagttttta ataataagac
    12121 aagaaaagag agcgtaaata tgctctctct ttttctcatt aacgaatgtt tataacgcaa
    12181 tcatgatgag agtattaata cagttaatta tttgaaatac tttagtttat ataatgttga
    12241 attataggta gtgaaattgt atttattata cattgtcata tcgttgttta atgatagtta
    12301 atttaaggat aatagaatta atattatata tagatgaaca aaacaagcaa cagagcagaa
    12361 aaaacacttt tagattattt ttactcattc tctattttat ttatttttgc tataataaat
    12421 aaagaatatt aaatggaggt gtttttatga aaaagaaatt tgtttctagt tgtattgcta
    12481 gtacaatctt attcggcact ttattaggtg taacttataa agctgaagct gcaacagtac
    12541 atgtagctgg tggtgtttgg agccatggta ttggaaaaca ttacgtatgg tcttattata
    12601 gtcacaataa aagaaatcat ggttcaacag cagtagggaa atattcatct tttagtggtg
    12661 ttgctcgacc tggtgttcaa tctaaggcat ctgctccaaa ggcttggggt ggaaacaaaa
    12721 cattttatag tcttcactaa ttacatatat taattaagga gaatagacag aattaagtaa
    12781 acttaattct gtctattctc ttgaaagagg caatatgaaa aaattcaaat tatttttaga
    12841 ttttagtact ttattattaa tttcagggct attattttta tttttcttca aagaaaatga
    12901 agaaattata cctgaaagtt ccaatatttt aacaatctct aattgggata aatctaacag
    12961 taaatcaaaa gtgttagatg tcattgaatc aggcgccaaa aatcaaaata tacaaataat
    13021 taaatccgtt aaagattttg ataataaaaa agaatttttt gttttcaact caaaacgaaa
    13081 taattctgac tttatacgta ataaaacatc acttttaact ccatcagatt tattaaacag
    13141 agagataaaa ggaaagtatt atattattgg tgaacatttc aatgtagaag agcttacgag
    13201 tgaattaaaa aaagctggtt taacatctga agttgaatac ataaatagaa acatattatt
    13261 ttttgaatta gtcatagata atgatttatt agtgcctttc atattcttag gcgtattata
    13321 tcttttgtac ttcttatatg acagaggata taatttgaaa ttttatgcta ttcaaaagct
    13381 acatggcttt tcaactacac gcattatttt tcataatatt catataaaaa tcatttattg
    13441 gctagtactt accgctattt tctttattgc taatatatta atcattcata tagccaattt
    13501 agaattggat ttcttaatgt ttattcgtag atttatcgtg ttgctttttg tttttgcttg
    13561 tattactaca ttgctgtggc tgatttcgta tagtcttctt ttgaagttaa gtattccatt
    13621 aatcttaaaa gggaaaaaag gatataagtt ttcaatattt atgggtacct tcaccaaatg
    13681 tatcatggtg ctaatactat cttttttact ggcacaaaat ttaaatgctt atacgaagtt
    13741 aaagaatata tatgactctg aaaaaatctg gcaaaagtta gataattact atacattaga
    13801 gatttctcct aatattagaa attcagaaga aaaacaaatt ttagaaacta atatatacaa
    13861 tttaattaag aaaagcgaac aacttggtgg attgctttta aagaataata atatagccaa
    13921 tcccgataaa aacaattaca ttcctgaaaa tggcaatgtc ttttttatca ataacaattt
    13981 tctgaatttc tataaaaata taaatcatga ttttaaaatg attgacaatc attcggataa
    14041 aataaacgtg tttattcctc caaggttaca atatcaaaaa tctgaaattc aaaaaaatca
    14101 ccaaggatgg attgactttc aaaagcaaca aaacaaaaaa gtagatgtgc aagtactgtc
    14161 aaaaaacgta tctgtttttt cttttgatcg cacaactaat ttgaaatttg ggtatctaga
    14221 ttctccaata gtaatgttgt tgacacttga cgatttaaca ggagattttt atttagctgc
    14281 tgtttctcaa ggtggatatc tatttaaaga tttagataca cttaaacagt tgcttaaaga
    14341 taatcaccta gaagaagaaa ttagcggtat aactaattac aaggattctg tgttaaatga
    14401 attaaatgaa acgaaaacaa aaatgataat aacaatagtt actattatta ttaacgtttt
    14461 cattcttttg atagctactg tatttgaaac aattcaatat tttagctgga ataaaaagca
    14521 actattatta agaaaaattc atggttattc attattcagc agtaatgtac gttatttaac
    14581 aatttctatc ttactttcta ttatgttagc ttacactacg catattttat ttggttcaaa
    14641 gatattacta ttcataataa tgtctattgc tattattcaa catttacttc aaattgctta
    14701 tattaaatat cttgaaaaat actttaaaga tttaatgagg gagatttaaa caatgaaaag
    14761 aactttaatt attgtaacaa ttgtactatt aatcatcata cttagtctgt tattggttag
    14821 aaatgagcat ttagatcgtt ttaacccact gttaaaagaa aaagtatctt atgccaaagt
    14881 tccaaaagat acccaggact atagaaatat aactgtatac tctaaaaatg gagaaaaaaa
    14941 gagttataaa ttggattttt taggttatga tcctacaaaa gaatatgtga aagtaaatca
    15001 taaagggaaa tatgtgcgtt cgatagaata cattacaaaa gatattccta gctttttaaa
    15061 atgaggtgac cgatagtgat aaaacttgaa aatgtttttg taaaaaaagg taataaaaac
    15121 attttagacg gatgtaactt taattttgaa aaaggaaaat catatgcttt agttggagaa
    15181 agtggcgctg gaaaatctac tttacttaac ataatcgctg ggttcgaaga tgtatcacaa
    15241 ggaagcatat atattgaaga taagttacta aaaaagaaag tcgattttta tagatatacg
    15301 ttagggtatt tgtttcaaaa ttttgcttta cttgaaaatc aaacaatcag tcaaaattta
    15361 gatttagccc taaagttcaa aaagaataaa aaagataata tgaacttaaa gaaagaagta
    15421 ttaaaaaagg tcggcctaga tttagatatc aagagaattg ttagttctct aagcggtggt
    15481 gaacaacaaa gagtagcatt ggcaagatta atattaaaag atccgaaaat cattttagct
    15541 gatgaaccta ctgggtcact agatacgaaa aatggaaaaa tagttattga tttattattg
    15601 aagctacttg atgaaaataa aactatgatt gtcgtaacgc atgatttaga gcttgcgaaa
    15661 cgatttgatg tcatagtcaa tatttctgag cttagaagtt aagaaatatt gataggtata
    15721 gccatacata gagaaaaaac aatatgaaat atgattagtc attacttttg agttttttaa
    15781 tttaaggact ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca
    15841 cacgttttta atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt
    15901 ttaggtgtta taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga
    15961 gttgttaaag tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa
    16021 aataaaaatt atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta
    16081 gtcaatgata ctaagtttga ttttaataaa aaattgatga gaaaatcgaa aaaaattata
    16141 aagggaaacg caaaattaga acagatgcca ttaaacatat tgatggatta attacatcag
    16201 ataatgtgtt ttttaatcaa ttatctgaag aagagacaaa atagtttttt aagcatgcta
    16261 aagcgttctt ggaagaagaa tacggtaaag aaaatctttt atatgcgaca gtacatatgg
    16321 atgagataac accacatatg cattatggcg tagttcctat tactaaagat ggacgtttaa
    16381 gtgcgaaaga agttgtaggt aataaaaaag cattaaccga attccaagat agattcaata
    16441 cgtatattaa taagcaaggc tatgatttaa aacgaggaat ttctagacaa cttacaaaag
    16501 aaaaacatga tcaagttagc cgttataaac aaaaaacaga atatcataaa caaatgcata
    16561 tgcgctagaa gcaaatagag gattatttaa agcaagaaaa tgataaattg atacaaaact
    16621 accaaaaatc attagatacg cttaaaaagc ttctgagtgt catgtatgaa attaaaacta
    16681 aaaatgtagg tggatggttt cataaagaga agcaagaaac aggcaatatt gtaattacta
    16741 aaactgattt tgaaaaatac actaaacaaa ttaaagcagc acagatgata ttagatgatt
    16801 atgaatgtat taaaagtggg aagtcattaa aaaaagcaga gaaacaaaat gaaagtttag
    16861 ttaatgaatt gactagtgtc catatggaaa atgaaaagct ggttgaagaa tttaatgatt
    16921 tagcacaacg ttataattat ttgttgtcag agaatgaaaa gaaagataaa gaactaaatt
    16981 atacgcttaa gttattcaat caagttttta aaatcattaa aagtatgatg aaagaagagc
    17041 gttatcatac actaataaat catattgata atcatttaga caattctaaa atacgtgaag
    17101 taatgacgat agataacaat gatgaacagt tctttaagaa gaaatatcaa gcacaagaac
    17161 gagaaatcat ttttaaagaa gatagagaag atggttatac attataaaaa tagatattta
    17221 aatgcatttg tttgaggtta attatttttt aggatgaaaa ataggtagcc cccctcgaac
    17281 tttttaatat atttttataa atctttttaa aaaccttttt aggggctttt tcagccctag
    17341 agcaacaagg gatttcaatg cctaaaggag tgtttttgcc acataaaagg agtgtttttg
    17401 ccacataaaa ggagtgtttt tgccacataa aaggagtgtt tttgccacat aaaaggagtg
    17461 ttttaaaaag ttgtactcct tttatggttt gacattgata ataaagtagt ttattgtgaa
    17521 taaaagtttt caaatgggag tgtatattca aacgatactc ctttaggttc gtaataaagg
    17581 gggctgtatc atgacaggag agacagttgt atataaaaat gaaatgaatt tagttccatt
    17641 aaggcgattt acagctactg aaattaattt attttttgcg atgtgtaata aattaaaaga
    17701 gcaagatact aatacattac gtttgtcttt tgatgaatta aaaaaattaa gtaattatag
    17761 tccagaaaca cgtaatatta atagatttgc taatgattta gataatgtgt ataaaaagat
    17821 gttgaattta accattagat atgaagatga tgatgtaata gaaagattcg ttttattcaa
    17881 tcattataga atccataagc gagaacaata tctagaaata tcaacttctt caaatttaaa
    17941 acacatattg aattcaatta ctaataattt tacaaaattt gaattaaaag aaatgactag
    18001 gcttaaatct acatattcta aaaatatgtt tagattactt aaacaataca aacatacagg
    18061 ctatttaaaa attcacatcg atgattttaa aaatcgttta gatataccta aatcttatcg
    18121 tatgactgat attaacaaaa atgtttttaa acctattatt attgaattag gttctatatt
    18181 taataatctt actatcaata aaatcaaagc gaaaaaaggg cgtaaaattg aatggataga
    18241 gttcacattt gacgctgaga aacgcattca taacaaacga caacctcaaa tgtccaagat
    18301 agataaatca agacaatatg tgaggcgtga aaagacgcct aaatggttag aagaacggtc
    18361 atatgaaaag caacctcaaa aagattacga cccacaatta gagaaagaac gagaggattt
    18421 tttaaaacaa cttgaactga attgggaata acgcaacttt tcgttgcgag ttggttaact
    18481 aaaagtatcg tgacttttca attattttaa ttatagtttg agttaaggag tgattttatg
    18541 aaattagctg aagctataaa agaacagaga gaattaaaag gatggtctca agaggaatta
    18601 gccaatatat taaaggtttc cagacaaagt gtttctaaat gggaaagtgc caaaaactat
    18661 ccttccttag atattttgat tgctatgagc gatttattcg gaatctcttt agagcattta
    18721 attaaaggag atgcacgttt taaaaaagtt attttagagg gaaattatag agagagtaac
    18781 agggtacctt ccatagttga ttttctttat gatttttggt ggcttttctt tcctgttgcc
    18841 ggatttttag tttgggccat tcattcgttc atgggttgat tttaaaatca aaatttaatg
    18901 cacatcaggc aatatgaaaa aggaaagtat ttttacgaca ccttgaaatg tattgataag
    18961 aatagaagag tttacaaaag gcaatatgaa atatatacta aaagtaacaa gaatttcgtt
    19021 tgtaaacgca caaaaccccg aactattcgc cgtagttcgg ggttttttgg tgaattggct
    19081 ttaatcgtct atattatttt ttatcacgtt tatggagcta ataaccaaat aacgtaacga
    19141 gacaaccact gattgccgtt gtcatgatgt gaacaagaat ttcattcata aatcgcacct
    19201 cctctctacg ccgaattgac atctgagaga tagacgacct tcacattata acaaatctct
    19261 ccttccatga aataacatga atattaataa atgttgttat atattaaaga taaataaata
    19321 taagggtggg attgataatg tttggcgatc aaagacaaga agctacaaaa tatgtcatta
    19381 aagaaggtta tcaagatatt tatttcctca acaaaaacgg ggaatggtat tatttcgaag
    19441 taagaagtgt ctggcgtggc aaacatatta ttagagttaa agatggtttg ttaggttgga
    19501 gaaaagaaat agtaactgaa taaagataca aaatacttgc caatgcaaaa gaatgaaaac
    19561 gcgtcaaatc aacgatgtat aaaagatgca taaaagataa tgaaagtaaa aagccataaa
    19621 tgccgtcata taggcattta tggctttttg tttggttaac ataatcgatg attatcagaa
    19681 gttcaattca cataaaaaag cacggctaat ttatgaactt gtcgtacctt tttaattaaa
    19741 attagttacc aaatagacga ctccaaaacc cctttttagg ttccgtttct tcactctttt
    19801 cttctatatc actatcattg tcatttggat tagctgaaac gtcttctctt tgtgcttctt
    19861 caccttgtgt actttcgtcg ctttgacttc cagatatatc cttatattga atctctgttt
    19921 ctttagtttc ttcctgatct cggttaatat ttacaggact agtagtatat gttttttctt
    19981 gtgcatcaac gttttgtcta gcgttagtag atgtatcaaa gggataatta aggtgttttt
    20041 ctttttctaa ttgattttct aatttttgaa tctttttatt actctctaat gccagaactt
    20101 gctgattctc aagcaatttt gatctttctt gcaactcttt tctgtaaaat tcaattgttg
    20161 tttcatgacg actttcttgt ttttcaattt gattatttaa agtattaatc tgatttttaa
    20221 gtatttctac tatttgagca tcgcttttag attcaaaatt aatattatcc gactcttttt
    20281 tttgtttgtc ttcagtagca ctttcaaaac catatttctt tttattttca tttactcttt
    20341 gaatgatttt ttctatatcg gtatcttctt taataaacga agtgttttcc tgttttattg
    20401 tctctatatt caatctctta atattattaa aaatcgtttg cttactaacc cctaattctt
    20461 cactcaacct ttttacactt ttcatatcat caacccttta taaaatgttt ataaaccctt
    20521 agtaaaatat tataagctta taacgattaa taataaagta atcgacaaat aaaaatataa
    20581 attcgccaac ctttttatca agggtttgta aagggtttat ggtgtttatc aaaggtttat
    20641 aaacctatat tttccctttt ttaagtttat tcaaagtgct ataataacct taatataaca
    20701 aaaaccccaa ctactggtaa tagtcggggt
//
