LOCUS       CP127774               20651 bp    DNA     circular BCT 19-JUN-2023
DEFINITION  Staphylococcus aureus strain C96 plasmid pC96_1, complete sequence.
ACCESSION   CP127774
VERSION     CP127774.1
DBLINK      BioProject: PRJNA914892
            BioSample: SAMN32360831
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20651)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Hybrid Oxford Nanopore Technologies Illumina Sequences of 174
            Staphylococcus Aureus Isolates from Chronic Rhinosinusitis Patients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20651)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUN-2023) Department of ENT Surgery at the Basil
            Hetzel Institute, Adelaide Medical School, The University of
            Adelaide, 37 Woodville Road, Woodville South, SA 5011, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-NOV-2022
            Assembly Method :: Flye for Genome, plassembler (Unicycler) for
            plasmids v. 2.9.1 (Flye) with short read polishing, 0.1.1
            (plassembler) with 0.5.0 (Unicycler)
            Assembly Name                     :: C96
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 69x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/12/2023 14:48:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,784
            CDSs (total)                      :: 2,705
            Genes (coding)                    :: 2,641
            CDSs (with protein)               :: 2,641
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 30 of 64
            Pseudo Genes (internal stop)      :: 12 of 64
            Pseudo Genes (multiple problems)  :: 17 of 64
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20651
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="C96"
                     /isolation_source="Patient Sinus Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pC96_1"
                     /geo_loc_name="Australia: Adelaide"
                     /lat_lon="34.9285 S 138.6007 E"
                     /collection_date="2012-06-20"
                     /collected_by="ENT Surgery Department at the Queen
                     Elizabeth Hospital, Adelaide, Australia 32"
     gene            166..842
                     /locus_tag="PCM71_13800"
                     /pseudo=""
     CDS             166..842
                     /locus_tag="PCM71_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            853..1135
                     /locus_tag="PCM71_13805"
                     /pseudo=""
     CDS             853..1135
                     /locus_tag="PCM71_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2343..2960
                     /gene="cadD"
                     /locus_tag="PCM71_13810"
     ARG             2344..2957
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2979..3326
                     /locus_tag="PCM71_13815"
     CDS             2979..3326
                     /locus_tag="PCM71_13815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WJC44932.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3495..3587
                     /locus_tag="PCM71_13820"
     CDS             3495..3587
                     /locus_tag="PCM71_13820"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJC44933.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3799..4773
                     /locus_tag="PCM71_13825"
     CDS             3799..4773
                     /locus_tag="PCM71_13825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WJC44934.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4893..5708)
                     /locus_tag="PCM71_13830"
     CDS             complement(4893..5708)
                     /locus_tag="PCM71_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WJC44935.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5701..7144)
                     /locus_tag="PCM71_13835"
                     /pseudo=""
     CDS             complement(5701..7144)
                     /locus_tag="PCM71_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(7116..7709)
                     /locus_tag="PCM71_13840"
     CDS             complement(7116..7709)
                     /locus_tag="PCM71_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WJC44936.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7973..8353)
                     /gene="blaI"
                     /locus_tag="PCM71_13845"
     ARG             complement(7977..8353)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8343..10100)
                     /gene="blaR1"
                     /locus_tag="PCM71_13850"
     ARG             complement(8347..10100)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10207..11052
                     /gene="blaZ"
                     /locus_tag="PCM71_13855"
     ARG             10208..11049
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11421..11954
                     /locus_tag="PCM71_13860"
     CDS             11421..11954
                     /locus_tag="PCM71_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WJC44940.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12368..12661
                     /locus_tag="PCM71_13865"
     CDS             12368..12661
                     /locus_tag="PCM71_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WJC44921.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12736..14670
                     /locus_tag="PCM71_13870"
     CDS             12736..14670
                     /locus_tag="PCM71_13870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WJC44922.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14674..14985
                     /locus_tag="PCM71_13875"
     CDS             14674..14985
                     /locus_tag="PCM71_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WJC44923.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            14997..15623
                     /locus_tag="PCM71_13880"
     CDS             14997..15623
                     /locus_tag="PCM71_13880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WJC44924.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15861..16490
                     /gene="mobV"
                     /locus_tag="PCM71_13885"
                     /pseudo=""
     CDS             15861..16490
                     /gene="mobV"
                     /locus_tag="PCM71_13885"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16530..17129
                     /locus_tag="PCM71_13890"
     CDS             16530..17129
                     /locus_tag="PCM71_13890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WJC44925.1"
                     /translation="MIQNYQKSLDTLKKLLSVMYEIKTKNVGGWFHKEKQETGNIVITK
                     TDFEKYTKQIKAAQMILDDYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFND
                     LAQRYNYLLSENEKKDKELNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIR
                     EVMTIDNNDEQFFKKKYQAQEREIIFKEDREDGYTL"
                     /name="recombinase"
     gene            complement(17171..17455)
                     /locus_tag="PCM71_13895"
     CDS             complement(17171..17455)
                     /locus_tag="PCM71_13895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJC44926.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            17513..18373
                     /locus_tag="PCM71_13900"
     CDS             17513..18373
                     /locus_tag="PCM71_13900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WJC44927.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18460..18801
                     /locus_tag="PCM71_13905"
     CDS             18460..18801
                     /locus_tag="PCM71_13905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WJC44928.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19040..19111)
                     /locus_tag="PCM71_13910"
     CDS             complement(19040..19111)
                     /locus_tag="PCM71_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJC44941.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19260..19445
                     /locus_tag="PCM71_13915"
     CDS             19260..19445
                     /locus_tag="PCM71_13915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJC44929.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19664..20407)
                     /locus_tag="PCM71_13920"
     CDS             complement(19664..20407)
                     /locus_tag="PCM71_13920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WJC44930.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10208..11052
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7368..17661
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17514..18373
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19665..20407)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15862..16136
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atactgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttagacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata aaactatatg aatcacccct aaatctttaa aatgccctct taaaattcaa
     1621 aataagggca taaaaaataa aagcccccca gataaagtga ggtagctttt tctttcgacg
     1681 ccgtatcgtc gatgtaattc aaaaaagtta tgggctataa atctacatca ctttttcaag
     1741 aatgtagtag caatattcaa cgcaaattaa tttttataac tgctcggaat atctcaagcc
     1801 gtttctttaa ttttgaaata aaaaaatcga cgaaggtcga ttacgttttt gcacatgtcg
     1861 atttatccga cgtataagtg cgcccttacg ggatttaact agattataac gacgaatttt
     1921 agacctgtaa agcaataaca attaggtcta ccaggtagat aaagtgtaca aagtagaacc
     1981 gaaaaagtta tttattttga agatttttcg tagatataat ttgctaataa acttcctaaa
     2041 actgaataaa gaaaaatagt taaactcatg taatcactcc ataattctga agtgtctcca
     2101 tgtctacgca tagacacgca tttatgccga gaaaatttat tgtgcgttga gaagaaccct
     2161 taactaaact tgcagacgaa tgtcggcata gcgtgagcta ttaagccgac cattcgacaa
     2221 gttttgggat tgttaagggt tccgaggctc aacgtcaata aagcaattgg aataaagcac
     2281 ctatgattat ttaaaaatat aagttataat acattcaaaa atatttttga atgaggtgta
     2341 ttatgattca aacggttgtt gctgctgctg ttctttatat tgctacagca gttgatttat
     2401 tagtaatttt attaatattt tttgctagag caaagactag aaaagaatat agaaatattt
     2461 atgttggtca atatttaggg tctattattt taatattagt tagtttgttt ttagcttttg
     2521 tattaaatta tgttccagaa aagtggatat taggtttatt gggtttaata ccaatttatc
     2581 ttggaattaa agtggctatt tatgatgatt gtgaaggaga aaagagagct aaaaaagaat
     2641 tgaatgaaaa aggattgtct aaattagttg gtacggttgc aattgttacg atagcaagtt
     2701 gtggcgccga taatattggt ttatttgttc cttattttgt gacattaagt gttactaatt
     2761 tattacttac tctgtttgtc tttttaattt taattttctt cttggtgttt actgcacaaa
     2821 aattagctaa tatcccagga attggagaaa ttgttgagaa atttagtcgt tggattatgg
     2881 ctatcattta tatagcttta ggtttattta ttattattga aaatgacact attcaaacaa
     2941 ttttaggatt tatattttaa tttagggtgt gattttatat gagttatgaa aatacttgtg
     3001 atgtgatctg tgtacatgag gataaagtta acaatgcttt aagtttttta gaagatgata
     3061 aatctaagaa attacttaac attttagaaa aaatttgtga tgagaagaaa ttgaaaatca
     3121 tattatcttt gattaaagaa gatgagttgt gtgtttgtga tatttctttg atattgaaaa
     3181 tgagtgttgc ttcaacttca catcatttaa ggcttttata taaaaatgag gtacttgatt
     3241 tttataaaga tggaaagatg gcatattatt ttattaaaga cgatgaaata agagagtttt
     3301 tctctaaaaa tcaggagggt ttttgaaacg agtgaaacga gtttcttctt gtcttgatac
     3361 tataaaaaac aaagttatat aacataagac gacttatcgg aagttatcta tcatcgtata
     3421 ttcggagatg atataatata caggtcgcct atctctcagg cgtcaattca gacgcagaga
     3481 ggaggtgcat tactttgcta atcattttcg ttcacatcat agcaccagtc atcagtggct
     3541 gtgctgttgc gtattatact tattggctta gtaaacgcaa caaataatta ataggcgact
     3601 ttataagcca gcatcgaaaa aatccccaca ctattgcagt agtgtgggga ttggtgcatt
     3661 aattgttaat cattttcgtt atctagatta taacactggt tagtagagga atgcaaaaag
     3721 ataatatttt aagtagtctt tttggatatt atcatatgat atatttatgt aaattgattt
     3781 tttattaaag gagcatatat gagtaatact aaaattaaat atcaaatttt tatttcatca
     3841 acttatttag atttaataga agagcgtcaa gcagtagtag aagcagtttt aaacagtaat
     3901 aatattccag caggtatgga actttttaac tcaagtagta aaagccaatg ggaaataata
     3961 acacaatgga tcaatgaatc agatgcagtg atattattgt taggttctag ttatggaaca
     4021 attgatagtg aagaaaatat tagctataca gaaatggagt acaattttgc taaatcttta
     4081 ggtaaaccta tatatgtttt tgagatgaat aaagcatcta ccgaatccgc ggaaaagtct
     4141 aaaaaattag atgagtttaa gacaaaagtt aaagaaaata gactaattag tccaaatatt
     4201 aatgatattt cggaattaaa aagtaaagta tctcagactt taatgcaaag tgtacctagt
     4261 gaaattaaag aaaatagtgg atggataaga gtacaggatt gtggtaaaaa tgtaaaaaaa
     4321 ttaaaaaaat tggatgctat acaaagagat ttagatacat atgatttttt gaaagaagaa
     4381 ctttataaaa tattcatgta tgtaaaaact ttttatttcc agcacacacc atttgatgat
     4441 agttatattg aagatataga aaactacctg ctaaattatg aaaataatcc acataaatca
     4501 ttcatgaaaa taaaagttta tgattataaa aactttttaa aacatttaaa aaacatattg
     4561 attttaatta aacaaggaaa aaagccatta gctcaagccg gtcattttaa attaagcttt
     4621 tacgaagagg atttaaaatt gttacaaaaa aattataagg ctacgctagt cgatattaaa
     4681 ggattgaata aacattttta taaggaatgt gataggtgct taaaagcata taatattttt
     4741 attgagggta taaataaaca tttatatgaa tgatataagt acaccctaat catacatata
     4801 taattgttgt cactttactc gatatatgag aatgacttta cctaataaat gagaaaagca
     4861 acgcactata ttaaaatgcg ttgctttttc tattatcgaa tacctataac taaactatct
     4921 ctagctgttt ctacaacttc tgtacttatt ttatctaaac catttatatc cataattctg
     4981 tctatctgcg caaataaacg atgaatcagc ctaaaattcc cttttgtaat tttaataatc
     5041 gtcgttattg cctcataatc agtaaagtct tcgagtttta aatcaaatcc taagtcttgc
     5101 cacttatatt ctaatatatg atgcgtctca tctttactta gattatcaaa ttcatgcgca
     5161 aaacctatac gcgaatatag ttgaggataa cgagatagtt ttttctctat acccggcata
     5221 ccaataaata tcattgctaa attatgttca tcataaatag ctcttaattg ctctaaatgt
     5281 tgcactttaa ggcgatcaat ctcatctact ataattaaat caatatattt aaacatatca
     5341 ctataatgtt tactatgttc atgtccatac ttatttacaa catgtaattt ttgacccaaa
     5401 tcaatgattg cagtaatact atataaatca ttccttaatt tagtttgttt ttctgctggt
     5461 gcattataaa atattttatc caccgatagt atgtcatcgg tcgttttact agctaaatct
     5521 tcccaacctc tatggttaac ttgtttttca atagtatccc aatttgtgta atacctagac
     5581 gataaagttt ttccgacacc aggttgacca taacatatac caatatactg atatttaata
     5641 caagcatcac aaaattcagc aaagcgttta tactctttcg tttcaatgaa attttgattt
     5701 ttagtcatta cgatatctct ttaatttttt gacgttttta gtcgtttctt gaggtgaata
     5761 accacaattt ttttcttcct taattaattc cgtggtactt ggactagcaa tattttgttt
     5821 taagtgtttt cttctctgac tacgagcgtg ctgtatgtct tttatatcta tggagtaatc
     5881 agctatttct ggacatatag cagtacaaag aaattcatct ctataaaaca cacgtatttc
     5941 agccatatca tttgggttat aacgaatcag tacatattca cctacataag cttctagatt
     6001 agtattactg tatcgaaaac cttgaaaatg aatgccatct gaatgaactt ttctagattt
     6061 aggtatttcc aacaataata aatcaagttg ttctaagcta cttggcatat tagggaaaaa
     6121 gtgattacta ttccaatgac tgataggcgt ggtatgaata gtactatgtt ctttttgatt
     6181 ataatcttca attaaaaagt aacgtaattt ttcttcaaaa ttgtgaaaat ttattagatt
     6241 actaggagta tcattattgt ttatatatcc aggcagttgt tctaagaaag tttgattaac
     6301 tgtctgaaag aatcgttcta tttttccacg accacgagga acaccaactt tcgaaaacat
     6361 caagttaatt ttcaaatcaa tagcgacttg ttccatatga tgtgaagtaa agtcacttcc
     6421 atgatctgtg tagaattttt cgggtatacc acacactggc caattggtat catttttatt
     6481 ccatattgct tggtgtagtg ttaatgctgt gttttgagca ttggggggca tcaaaactta
     6541 agaaatagcc tgcaattgca cgactatagt catccataat aatagttagc catggtctat
     6601 tgatattacc tttttggtct aatataaaga tatctagcaa agtatggtct gcttgccata
     6661 tttcattggg tctcgaggat tctctaattt gtattaaatc gtacttattt tgatagtatt
     6721 tttcaccctg atgagagaaa tcaataacag acttaggcat cgctttaata acactataaa
     6781 tttgtttata acttggtata tcaaaattat tttctttaca gtaattagtg attttcctat
     6841 gaattgtggc tatactattt cttttattca taagcgcaag gcgttcaatt tcatcaatta
     6901 tctttggttc tattttacgt gttcctttat cagctcttgt cgcatagatt agtcctttaa
     6961 gtccttgttc tttatatgac ttattccacc tataaagggt gcttaacgca atccctttac
     7021 ttttagaaat acttgataaa gattgttcgc ctaggataaa aggttttata atattgtact
     7081 tttgagtagc ttttttacgt ttggcttcag aaaaattagt tagatacttc tccttgtttt
     7141 tcatcttcct tgtcctccaa tttattgagg taacgataaa ttgttgtacg tgaaacatgc
     7201 cactgttctg caattgtctt aattggcgtg ccattatcat aaagggtctt aagtaagttt
     7261 aaatcttttt gatttaattt ttctggtctg cctccatatc ggcctctagc acgtgctgca
     7321 attcggccag ctgaagaacg ctctaaaatt aaattacgtt caaattctgc aaatgctgcg
     7381 aataaatgaa ataataattg tccagttgaa cttgatttat ccattgttat attttcttct
     7441 aaactatgga aacttacacc tcgttcgtta agctcattaa ctaatgtgat taaatcctcc
     7501 atattacgtc ccaatctatc taatctccaa acaacaatcg tatctcctga cctcgcaaat
     7561 tcaattgctt tatctaaacc aggtctttta ctttttgaac cactcatatg gtcattaaat
     7621 atcttttcac aaccatatgt atttaatcga tcctcctgta aatttaaatt ttgtaatcca
     7681 gttgaaactc ttgcataacc tattttcaaa atacaaacct cctatataca tcttcagtgt
     7741 accataactt aattacaagg tcttttatga acatagattt tttgttgggt ttttgaacac
     7801 ataatcctat gtaattctta cttatttaga cataaaagaa gagtgtacag aaaatggtta
     7861 ttttctgtac actctcatct ttaataatat attttaaatg tcattaacaa aactaattta
     7921 ataagagtca agcatagttt acatatgtat tatgtttgaa acatacctct aattactttt
     7981 tactaatatc atttaaaata tctcgcaatt cttcaatttc tttgttattt aattcttcat
     8041 ttttcgcaaa attcaacact aaacttttca tatcccctcc atacagttta ttaagaaagg
     8101 ttttagcagt tttcatttta atatcgtctt ctttaatatt tgatgagtaa aaataaatat
     8161 tttctgattt gtatcgtttt ataatctctt ttttatatag tcttgtgatt aatgttctaa
     8221 tcgttttatc actaacttct ttatattttt gaatttcaac tacaatttca ttagctgata
     8281 ctgatttttt atcccatatt atattcataa catcccattc agccatagat atttcaactt
     8341 gcttattggc catttaaaac acccattcct tttaatattt tttcacttat taattcagca
     8401 tttttcccag acgggtttcc atctgataaa tgtgtagcaa aataatactt atcatgattt
     8461 gtaattacgt aacctacaaa ccacccatta ttatacttcc cgtttactat acctgtacct
     8521 gttttcccat acagttcata cttttcattt ttcttaatca ataatgaaga agataattga
     8581 ttctttgctt ttttactaaa atggttattt tgttccatca tatttttaaa aactattact
     8641 tgttcaagat tagatatttt caaactatct tccatccaat agcttttata acttcccaaa
     8701 ttttcattac cataatttaa ttgcttgagt tgagccgcag tatagttctt tggtatttga
     8761 ttactaatac gttcgaagta ccaattaact gaattttgca ttgctgtatt taaatcttgt
     8821 tccttattcc aagactcgaa aagataatgt ttatgattcc atgacatacg tgaattttta
     8881 tcacttataa tatgacggtc aagtccaaac agtgctaaat aaattttgta agttgaatca
     8941 ggagaatatc tttttctact ttctttttca ttataaatat agtatttgtc tttcttcatg
     9001 ctgtacataa cgaaagatcc actatttgaa ccaaaatttt tactttcatc taaaatttgg
     9061 taatcgcttt gtaagggctt tttataatta taatcagtta aggattgccc cattaaaaac
     9121 tggctttgaa ttatcatgat aaaaaaagta aaaatacaaa taaaaattag aattaatttt
     9181 gactgctttt tcagatcggc ttcttttata ttaattaatc tatttttgag taatgatttt
     9241 ttaccattaa atgaatggct taatatattt ttgttgaaaa atgaggtttt taatacggag
     9301 tccataatag attccgcata agttttaaat tcatttttgt taatattatt aaggacaaat
     9361 ctatcggctt ctacttcatt gtcatgaatt atctttcttt ttacaatatg tactaatgga
     9421 ttgtaactca taataataga gaagatatta aagataatta aatgtaaagt atctctattt
     9481 ttagcatgag catattcatg cagtattata tattttagtc ttttatcaat tacactttta
     9541 aaatatgaac taggaatcaa aataatatat ttcccatacc aaaaagttat tggagattga
     9601 atagcctctg cttttcgaat cacaatattt tttttatatt gatggttgaa aagtatcgta
     9661 tctattttat ttttttcatt ttcgtttaga taaagtgact gtttctttaa atatttaaga
     9721 tataataagg ctttcaaaaa tttaaaactt aaaataataa ctaaaactat ccaaataact
     9781 gtgcagatat tatcaattga atcccaatta aacttatgga tatctgttgc gaactcttga
     9841 acaggtttgg tggtaattat gttatggttc aagtcgtgtg acttactttc aactgtgggc
     9901 gcttgattat tcacattatt aaattttata aaagagaatt taattgggat aaaaggaatt
     9961 aatccagcaa gcacagttag ataccaaact ttataattta aactataatt aaaatagcgt
    10021 tttaatatgt acctaaaaaa tactaacaat agaaatataa aacaaaagct tactacactc
    10081 attattagta atttagccat tttgacacct tctttcaaat atttataata aacaattgac
    10141 atcaatatta caattgtaat attattgttt tgtaaaaatt acaactgtaa tatcggaggg
    10201 tttattttga aaaagttaat atttttaatt gtaatggctt tagttttaag tgcatgtaat
    10261 tcaaacagtt cacatgccaa agagttaaat gatttagaaa aaaaatataa tgctcatatt
    10321 ggtgtttatg ctttagatac taaaagtggt aaggaagtaa aatttaattc agataagaga
    10381 tttgcctatg cttcgacttc aaaagcgata aatagtgcta ttttgttaga acaagtacct
    10441 tataataagt taaataaaaa agtacatatt aacaaagatg atatagttgc ttattctcct
    10501 attttagaaa aatatgtagg aaaagacatc actttaaaag aacttattga ggcttcaatg
    10561 acatatagtg ataatacagc aaacaataaa attataaaag aaatcggtgg aatcaaaaaa
    10621 gttaaacaac gtctaaaaga actaggagat aaagtaacaa atccagttag atatgagata
    10681 gaattaaatt actattcgcc aaagagcaaa aaagatactt caacgcctgc tgctttcggc
    10741 aagactttaa ataaacttat cgcaaatgga aaattaagca aaaaaaataa aaatttctta
    10801 cttgatttaa tgtttaataa taaaaacgga gacactttaa ttaaagatgg tgttccaaaa
    10861 gactataagg ttgctgataa aagtggtcaa gcaataacat atgcttctag aaatgatgtt
    10921 gcttttgttt atcctaaggg ccaatctgaa cctattgttt tagtcatttt tacgaataaa
    10981 gacaataaaa gtgataagcc aaatgataag ttgataagtg aaaccgccaa gagtgtaatg
    11041 aaggaatttt aatattctaa atgcataata aatactgata acatcttata gtttgtatta
    11101 tattttctat tatcgttgac atgtataatt ttgatatcaa aacctgattt tccctttatt
    11161 attttcgaga tttattttct taattctctt taacaaacta gaaatattgt atatacaaaa
    11221 aatcataaat aatagatgaa tagtttaatt ataggtgttc atcaatcgaa aaagcaacgt
    11281 atcttattta aagtgcgttg cttttttctc atttataagg ttaaataatt ctcatatatc
    11341 aagcaaagtg acataattgt tgaatttata gtaactgaaa cgtatgatta gggtgtatat
    11401 taattatgag atggaaatca atgattgttg gctatgcgag agtatcatcg aacgatcaaa
    11461 atttagaaag acaacttgaa aatttaaaga cgttttgtgc tgaaaaaata tttacagaaa
    11521 aacagtctgg gaaatctatt gaaaatagac cagtacttca agaagcactt aactttttga
    11581 ggatgggaga tcggtttgta gtagaatcca ttgattgttt aggtcgtaat tatgatgaag
    11641 tggttggcaa tccattactg gataagttta tgaaagattt aattattcaa atattagcaa
    11701 tggtttcaga acaagagaga aatgaaagta aacgtcgaca agcgcaagga attcaagttg
    11761 cgaaggaaaa aggcgtatat aaagggcgcc ccttacttta ttcaccaaat gctaaagatc
    11821 cacagaaacg tattatttat catcgcgttg tagaaatgtt agaagaaggc caatcaatta
    11881 gtaaaattgc gaaagaagta aatataacaa ggcagacgat ttacagaatt aaaaacgata
    11941 atgatttgat ttaataaact ttgtttcaat gcaactgaga gcttctcaca gcgtctcaaa
    12001 acagatgatt ataatctatt atgagttttt aataataaga caagaaaaga gagcgtaaat
    12061 atgctctctc tttttctcat taacgaacgt ttataacgca atcatgatga gagtattaat
    12121 acagttaatt atttgaaata ctttagttta tataatgttg aattataggt agtgaaattg
    12181 tatttattat acattgtcat atcgttgttt aatgatagtt aatttaagga taatagaatt
    12241 aatattatat atagatgaac aaaacaagca acagagcaga aaaaacactt ttagattatt
    12301 tttactcatt ctctatttta tttatttttg ctataataaa taaagaatat taaatggagg
    12361 tgtttttatg aaaaagaaat ttgtttctag ttgtattgct agtacaatct tattcggcac
    12421 tttattaggt gtaacttata aagctgaagc tgcaacagta catgtagctg gtggtgtttg
    12481 gagccatggt attggaaaac attacgtatg gtcttattat agtcacaata aaagaaatca
    12541 tggttcaaca gcagtaggga aatattcatc ttttagtggt gttgctcgac ctggtgttca
    12601 atctaaggca tctgctccaa aggcttgggg tggaaacaaa acattttata gtcttcacta
    12661 attacatata ttaattaagg agaatagaca gaattaagta aacttaattc tgtctattct
    12721 cttgaaagag gcaatatgaa aaaattcaaa ttatttttag attttagtac tttattatta
    12781 atttcagggc tattattttt atttttcttc aaagaaaatg aagaaattat acctgaaagt
    12841 tccaatattt taacaatctc taattgggat aaatctaaca gtaaatcaaa agtgttagat
    12901 gtcattgaat caggcgccaa aaatcaaaat atacaaataa ttaaatccgt taaagatttt
    12961 gataataaaa aagaattttt tgttttcaac tcaaaacgaa ataattctga ctttatacgt
    13021 aataaaacat cacttttaac tccatcagat ttattaaaca gagagataaa aggaaagtat
    13081 tatattattg gtgaacattt caatgtagaa gagcttacga gtgaattaaa aaaagctggt
    13141 ttaacatctg aagttgaata cataaataga aacatattat tttttgaatt agtcatagat
    13201 aatgatttat tagtgccttt catattctta ggcgtattat atcttttgta cttcttatat
    13261 gacagaggat ataatttgaa attttatgct attcaaaagc tacatggctt ttcaactaca
    13321 cgcattattt ttcataatat tcatataaaa atcatttatt ggctagtact taccgctatt
    13381 ttctttattg ctaatatatt aatcattcat atagccaatt tagaattgga tttcttaatg
    13441 tttattcgta gatttatcgt gttgcttttt gtttttgctt gtattactac attgctgtgg
    13501 ctgatttcgt atagtcttct tttgaagtta agtattccat taatcttaaa agggaaaaaa
    13561 ggatataagt tttcaatatt tatgggtacc ttcaccaaat gtatcatggt gctaatacta
    13621 tcttttttac tggcacaaaa tttaaatgct tatacgaagt taaagaatat atatgactct
    13681 gaaaaaatct ggcaaaagtt agataattac tatacattag agatttctcc taatattaga
    13741 aattcagaag aaaaacaaat tttagaaact aatatataca atttaattaa gaaaagcgaa
    13801 caacttggtg gattgctttt aaagaataat aatatagcca atcccgataa aaacaattac
    13861 attcctgaaa atggcaatgt cttttttatc aataacaatt ttctgaattt ctataaaaat
    13921 ataaatcatg attttaaaat gattgacaat cattcggata aaataaacgt gtttattcct
    13981 ccaaggttac aatatcaaaa atctgaaatt caaaaaaatc accaaggatg gattgacttt
    14041 caaaagcaac aaaacaaaaa agtagatgtg caagtactgt caaaaaacgt atctgttttt
    14101 tcttttgatc gcacaactaa tttgaaattt gggtatctag attctccaat agtaatgttg
    14161 ttgacacttg acgatttaac aggagatttt tatttagctg ctgtttctca aggtggatat
    14221 ctatttaaag atttagatac acttaaacag ttgcttaaag ataatcacct agaagaagaa
    14281 attagcggta taactaatta caaggattct gtgttaaatg aattaaatga aacgaaaaca
    14341 aaaatgataa taacaatagt tactattatt attaacgttt tcattctttt gatagctact
    14401 gtatttgaaa caattcaata ttttagctgg aataaaaagc aactattatt aagaaaaatt
    14461 catggttatt cattattcag cagtaatgta cgttatttaa caatttctat cttactttct
    14521 attatgttag cttacactac gcatatttta tttggttcaa agatattact attcataata
    14581 atgtctattg ctattattca acatttactt caaattgctt atattaaata tcttgaaaaa
    14641 tactttaaag atttaatgag ggagatttaa acaatgaaaa gaactttaat tattgtaaca
    14701 attgtactat taatcatcat acttagtctg ttattggtta gaaatgagca tttagatcgt
    14761 tttaacccac tgttaaaaga aaaagtatct tatgccaaag ttccaaaaga tacccaggac
    14821 tatagaaata taactgtata ctctaaaaat ggagaaaaaa agagttataa attggatttt
    14881 ttaggttatg atcctacaaa agaatatgtg aaagtaaatc ataaagggaa atatgtgcgt
    14941 tcgatagaat acattacaaa agatattcct agctttttaa aatgaggtga ccgatagtga
    15001 taaaacttga aaatgttttt gtaaaaaaag gtaataaaaa cattttagac ggatgtaact
    15061 ttaattttga aaaaggaaaa tcatatgctt tagttggaga aagtggcgct ggaaaatcta
    15121 ctttacttaa cataatcgct gggttcgaag atgtatcaca aggaagcata tatattgaag
    15181 ataagttact aaaaaagaaa gtcgattttt atagatatac gttagggtat ttgtttcaaa
    15241 attttgcttt acttgaaaat caaacaatca gtcaaaattt agatttagcc ctaaagttca
    15301 aaaagaataa aaaagataat atgaacttaa agaaagaagt attaaaaaag gtcggcctag
    15361 atttagatat caagagaatt gttagttctc taagcggtgg tgaacaacaa agagtagcat
    15421 tggcaagatt aatattaaaa gatccgaaaa tcattttagc tgatgaacct actgggtcac
    15481 tagatacgaa aaatggaaaa atagttattg atttattatt gaagctactt gatgaaaata
    15541 aaactatgat tgtcgtaacg catgatttag agcttgcgaa acgatttgat gtcatagtca
    15601 atatttctga gcttagaagt taagaaatat tgataggtat agccatacat agagaaaaaa
    15661 caatatgaaa tatgattagt cattactttt gagtttttta atttaaggac tggattttcc
    15721 agtccttttt tatgatgaca aaaaacaagc ctcgcagagc acacgttttt aatgacttat
    15781 ttggttttta ataagtctag tatgttaaaa cttttctgtg tttaggtgtt ataatcatat
    15841 gcagtggaag ttgatttatt atgtcttatt caattattcg agttgttaaa gtgaaatcaa
    15901 aaacaaatac aagaggtatt caaagacata ttcaaagaga aaataaaaat tatgaaaata
    15961 tagatattga tttaagtaag tcatatttaa actatgattt agtcaatgat actaagtttg
    16021 attttaataa aaaaattgat gagaaaatcg aaaaaaatta taaagggaaa cgcaaaatta
    16081 gaacagatgc cattaaacat attgatggat taattacatc agataatgtg ttttttaatc
    16141 aattatctga agaagagaca aaatagtttt ttaagcatgc taaagcgttc ttggaagaag
    16201 aatacggtaa agaaaatctt ttatatgcga cagtacatat ggatgagata acaccacata
    16261 tgcattatgg cgtagttcct attactaaag atggacgttt aagtgcgaaa gaagttgtag
    16321 gtaataaaaa agcattaacc gaattccaag atagattcaa tacgtatatt aataagcaag
    16381 gctatgattt aaaacgagga atttctagac aacttacaaa agaaaaacat gatcaagtta
    16441 gccgttataa acaaaaaaca gaatatcata aacaaatgca tatgcgctag aagcaaatag
    16501 aggattattt aaagcaagaa aatgataaat tgatacaaaa ctaccaaaaa tcattagata
    16561 cgcttaaaaa gcttctgagt gtcatgtatg aaattaaaac taaaaatgta ggtggatggt
    16621 ttcataaaga gaagcaagaa acaggcaata ttgtaattac taaaactgat tttgaaaaat
    16681 acactaaaca aattaaagca gcacagatga tattagatga ttatgaatgt attaaaagtg
    16741 ggaagtcatt aaaaaaagca gagaaacaaa atgaaagttt agttaatgaa ttgactagtg
    16801 tccatatgga aaatgaaaag ctggttgaag aatttaatga tttagcacaa cgttataatt
    16861 atttgttgtc agagaatgaa aagaaagata aagaactaaa ttatacgctt aagttattca
    16921 atcaagtttt taaaatcatt aaaagtatga tgaaagaaga gcgttatcat acactaataa
    16981 atcatattga taatcattta gacaattcta aaatacgtga agtaatgacg atagataaca
    17041 atgatgaaca gttctttaag aagaaatatc aagcacaaga acgagaaatc atttttaaag
    17101 aagatagaga agatggttat acattataaa aatagatatt taaatgcatt tgtttgaggt
    17161 taattatttt ttaggatgaa aaataggtag cccccctcga actttttaat atatttttat
    17221 aaatcttttt aaaaaccttt ttaggggctt gttcagccct agagcaacaa gggatttcaa
    17281 tgcctaaagg agtgtttttg ccacataaaa ggagtgtttt tgccacataa aaggagtgtt
    17341 tttgccacat aaaaggagtg tttttgccac ataaaaggag tgttttaaaa agttgtactc
    17401 cttttatggt ttgacattga taataaagta gtttattgtg aataaaagtt ttcaaatggg
    17461 agtgtatatt caaacgatac tcctttaggt tcgtaataaa gggggctgta tcatgacagg
    17521 agagacagtt gtatataaaa atgaaatgaa tttagttcca ttaaggcgat ttacagctac
    17581 tgaaattaat ttattttttg cgatgtgtaa taaattaaaa gagcaagata ctaatacatt
    17641 acgtttgtct tttgatgaat taaaaaaatt aagtaattat agtccagaaa cacgtaatat
    17701 taatagattt gctaatgatt tagataatgt gtataaaaag atgttgaatt taaccattag
    17761 atatgaagat gatgatgtaa tagaaagatt cgttttattc aatcattata gaatccataa
    17821 gcgagaacaa tatctagaaa tatcaacttc ttcaaattta aaacacatat tgaattcaat
    17881 tactaataat tttacaaaat ttgaattaaa agaaatgact aggcttaaat ctacatattc
    17941 taaaaatatg tttagattac ttaaacaata caaacataca ggctatttaa aaattcacat
    18001 cgatgatttt aaaaatcgtt tagatatacc taaatcttat cgtatgactg atattaacaa
    18061 aaatgttttt aaacctatta ttattgaatt aggttctata tttaataatc ttactatcaa
    18121 taaaatcaaa gcgaaaaaag ggcgtaaaat tgaatggata gagttcacat ttgacgctga
    18181 gaaacgcatt cataacaaac gacaacctca aatgtccaag atagataaat caagacaata
    18241 tgtgaggcgt gaaaagacgc ctaaatggtt agaagaacgg tcatatgaaa agcaacctca
    18301 aaaagattac gacccacaat tagagaaaga acgagaggat tttttaaaac aacttgaact
    18361 gaattgggaa taacgcaact tttcgttgcg agttggttaa ctaaaagtat cgtgactttt
    18421 caattatttt aattatagtt tgagttaagg agtgatttta tgaaattagc tgaagctata
    18481 aaagaacaga gagaattaaa aggatggtct caagaggaat tagccaatat attaaaggtt
    18541 tccagacaaa gtgtttctaa atgggaaagt gccaaaaact atccttcctt agatattttg
    18601 attgctatga gcgatttatt cggaatctct ttagagcatt taattaaagg agatgcacgt
    18661 tttaaaaaag ttattttaga gggaaattat agagagagta acagggtacc ttccatagtt
    18721 gattttcttt atgatttttg gtggcttttc tttcctgttg ccggattttt agtttgggcc
    18781 attcattcgt tcatgggttg attttaaaat caaaatttaa tgcacatcag gcaatatgaa
    18841 aaaggaaagt atttttacga caccttgaaa tgtattgata agaatagaag agtttacaaa
    18901 aggcaatatg aaatatatac taaaagtaac aagaatttcg tttgtaaacg caccaaaccc
    18961 cgaactattc gccgtagttc ggggtttttt ggtgaattgg ctttaatcgt ctatattatt
    19021 ttttatcacg tttatggagc taataaccaa ataacgtaac gagacaacca ctgattgccg
    19081 ttgtcatgat gtgaacaaga atttcattca taaatcgcac ctcctctcta cgccgaattg
    19141 acatctgaga gatagacgac cttcacatta taacaaatct ctccttccat gaaataacat
    19201 gaatattaat aaatgttgtt atatattaaa gataaataaa tataagggtg ggattgataa
    19261 tgtttggcga tcaaagacaa gaagctacaa aatatgtcat taaagaaggt tatcaagata
    19321 tttatttcct caacaaaaac ggggaatggt attatttcga agtaagaagt gtctggcgtg
    19381 gcaaacatat tattagagtt aaagatggtt tgttaggttg gagaaaagaa atagtaactg
    19441 aataaagata caaaatactt gccaatgcaa aagaatgaaa acgcgtcaaa tcaacgatgt
    19501 ataaaagatg cataaaagat aatgaaagta aaaagccata aatgcctata tgacggcatt
    19561 tatggctttt tgtttggtta atataatcga tgattatcag aagttcaatt cacataaaaa
    19621 agcacggcta atttatgaac ttgtcgtacc tttttaatta aaattagtta ccaaatagac
    19681 gactccaaaa ccccttttta gcttccgttt cttcactctt ttcttctata tcactatcat
    19741 tgtcatttgg attagctgaa acgtcttctc tttgtgcttc ttcaccttgt gtactttcgt
    19801 cgctttgact tccagatata tccttatatt gaatctctgt ttctttagtt tcttcctgat
    19861 ctcggttaat atttacagga ctagtagtat atgttttttc ttgtgcatca acgttttgtc
    19921 tagcgttagt agatgtatca aagggataat taaggtgttt ttctttttct aattgatttt
    19981 ctaatttttg aatcttttta ttactctcta atgccagaac ttgctgattc tcaagcaatt
    20041 ttgatctttc ttgcaactct tttctgtaaa attcaattgt tgtttcatga cgactttctt
    20101 gtttttcaat ttgattattt aaagtattaa tctgattttt aagtatttct actatttgag
    20161 catcgctttt agattcaaaa ttaatattat ccgactcttt tttttgtttg tcttcagtag
    20221 cactttcaaa accatatttc tttttatttt catttactct ttgaatgatt ttttctatat
    20281 cggtatcttc tttaataaac gaagtgtttt cctgttttat tgtctctata ttcaatctct
    20341 taatattatt aaaaatcgtt tgcttactaa cccctaattc ttcactcaac ctttttacac
    20401 ttttcatatc atcaaccctt tataaaatgt ttataaaccc ttagtaaaat attataagct
    20461 tataacgatt aataataaag taatcgacaa ataaaaatat aaattcgcaa cctttttatc
    20521 aagggtttgt aaagggttta tggtgtttat caaaggttta taaacctata ttttcccttt
    20581 tttaagttta ttcaaagtgc tataataacc ttaatataac aaaaacccca actactggta
    20641 atagtcgggg t
//
