LOCUS       CP127761               17766 bp    DNA     circular BCT 19-JUN-2023
DEFINITION  Staphylococcus aureus strain C72 plasmid pC72_2, complete sequence.
ACCESSION   CP127761
VERSION     CP127761.1
DBLINK      BioProject: PRJNA914892
            BioSample: SAMN32360841
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 17766)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Hybrid Oxford Nanopore Technologies Illumina Sequences of 174
            Staphylococcus Aureus Isolates from Chronic Rhinosinusitis Patients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17766)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUN-2023) Department of ENT Surgery at the Basil
            Hetzel Institute, Adelaide Medical School, The University of
            Adelaide, 37 Woodville Road, Woodville South, SA 5011, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-NOV-2022
            Assembly Method :: Flye for Genome, plassembler (Unicycler) for
            plasmids v. 2.9.1 (Flye) with short read polishing, 0.1.1
            (plassembler) with 0.5.0 (Unicycler)
            Assembly Name                     :: C72
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 45x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/12/2023 14:46:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,713
            CDSs (total)                      :: 2,631
            Genes (coding)                    :: 2,552
            CDSs (with protein)               :: 2,552
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 43 of 79
            Pseudo Genes (incomplete)         :: 26 of 79
            Pseudo Genes (internal stop)      :: 19 of 79
            Pseudo Genes (multiple problems)  :: 9 of 79
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..17766
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="C72"
                     /isolation_source="Patient Sinus Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pC72_2"
                     /geo_loc_name="Australia: Adelaide"
                     /lat_lon="34.9285 S 138.6007 E"
                     /collection_date="2012-03-26"
                     /collected_by="ENT Surgery Department at the Queen
                     Elizabeth Hospital, Adelaide, Australia 42"
     gene            complement(join(17759..17766,1..604))
                     /locus_tag="PCM65_13450"
     CDS             complement(join(17759..17766,1..604))
                     /locus_tag="PCM65_13450"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="WJB87115.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHDR"
                     /name="M56 family metallopeptidase"
     gene            711..1556
                     /gene="blaZ"
                     /locus_tag="PCM65_13455"
     ARG             712..1553
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(2082..2501)
                     /locus_tag="PCM65_13460"
     CDS             complement(2082..2501)
                     /locus_tag="PCM65_13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WJB87117.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            2625..3596
                     /locus_tag="PCM65_13465"
     CDS             2625..3596
                     /locus_tag="PCM65_13465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WJB87118.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(3768..3860)
                     /locus_tag="PCM65_13470"
     CDS             complement(3768..3860)
                     /locus_tag="PCM65_13470"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJB87119.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(4017..4364)
                     /locus_tag="PCM65_13475"
     CDS             complement(4017..4364)
                     /locus_tag="PCM65_13475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WJB87120.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(4383..5000)
                     /gene="cadD"
                     /locus_tag="PCM65_13480"
     ARG             complement(4387..5000)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(6116..6310)
                     /locus_tag="PCM65_13485"
     CDS             complement(6116..6310)
                     /locus_tag="PCM65_13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJB87122.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            6420..7112
                     /locus_tag="PCM65_13490"
     CDS             6420..7112
                     /locus_tag="PCM65_13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WJB87123.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(7280..7429)
                     /locus_tag="PCM65_13495"
     CDS             complement(7280..7429)
                     /locus_tag="PCM65_13495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJB87124.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(7976..8264)
                     /locus_tag="PCM65_13500"
                     /pseudo=""
     CDS             complement(7976..8264)
                     /locus_tag="PCM65_13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(8284..9267)
                     /locus_tag="PCM65_13505"
     CDS             complement(8284..9267)
                     /locus_tag="PCM65_13505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WJB87125.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            9693..10436
                     /locus_tag="PCM65_13510"
     CDS             9693..10436
                     /locus_tag="PCM65_13510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WJB87103.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(10652..10837)
                     /locus_tag="PCM65_13515"
     CDS             complement(10652..10837)
                     /locus_tag="PCM65_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WJB87104.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            10986..11081
                     /locus_tag="PCM65_13520"
     CDS             10986..11081
                     /locus_tag="PCM65_13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WJB87105.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGYWLHKRDKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11296..11637)
                     /locus_tag="PCM65_13525"
     CDS             complement(11296..11637)
                     /locus_tag="PCM65_13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WJB87106.1"
                     /translation="MKLAEAIKEQRELKRWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRAPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(11724..12584)
                     /locus_tag="PCM65_13530"
     CDS             complement(11724..12584)
                     /locus_tag="PCM65_13530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WJB87107.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(12947..13501)
                     /locus_tag="PCM65_13535"
     CDS             complement(12947..13501)
                     /locus_tag="PCM65_13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WJB87108.1"
                     /translation="MIQNYQKSLDTLKKLLSVMYEIKTKNVGGWFHKEKQETGNIVITK
                     TYFEKYTKQIKAAQMILDDYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFND
                     LAQRYNYLLSENEKKDKELNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIR
                     EVMTIDNNDEQFFKKKYQAQE"
                     /name="recombinase"
     gene            complement(13514..13840)
                     /locus_tag="PCM65_13540"
     CDS             complement(13514..13840)
                     /locus_tag="PCM65_13540"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="WJB87109.1"
                     /translation="MEEEYGKENLLYATVHMDEITPHMHYGVIPITKDGRLSAKEVVGN
                     KKALTEFQDRFNTYINKQGYDLKRGISRQLTKEKHDQVSGYKQKTEYHKQMYMREKQIE
                     DHLK"
                     /name="plasmid recombination protein"
     gene            complement(13780..14157)
                     /locus_tag="PCM65_13545"
     CDS             complement(13780..14157)
                     /locus_tag="PCM65_13545"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="WJB87110.1"
                     /translation="MSYSIIRVVKVKSKTNTRGIQRENKNYENIDIDLSKSYLNYDLVN
                     DTKFDFNKKIDEKIEQNYKGKRKIRTDAIKHIDGLITSDNVFLINYLKKRQNSFLSMLK
                     RSWKKNTVKKIFYMRQYIWMR"
                     /name="plasmid recombination protein"
     gene            complement(14395..15021)
                     /locus_tag="PCM65_13550"
     CDS             complement(14395..15021)
                     /locus_tag="PCM65_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WJB87111.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(15033..15344)
                     /locus_tag="PCM65_13555"
     CDS             complement(15033..15344)
                     /locus_tag="PCM65_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WJB87112.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(15348..17282)
                     /locus_tag="PCM65_13560"
     CDS             complement(15348..17282)
                     /locus_tag="PCM65_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WJB87113.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(17357..17650)
                     /locus_tag="PCM65_13565"
     CDS             complement(17357..17650)
                     /locus_tag="PCM65_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WJB87114.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     ARG             712..1556
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             12357..17766
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(7773..7920)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(7979..8153)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.135"
                     /coverage="94.0"
                     /evalue="4.83e-64"
     Typing          complement(8285..9267)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9694..10436
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(11725..12584)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13784..14157)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.2"
                     /coverage="100.0"
                     /evalue="1.03e-73"
ORIGIN
        1 catgcagtat tatatatttt agtcttttat caattacact tttaaaatat gaactaggaa
       61 tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc tctgcttttc
      121 gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt ttattttttt
      181 cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat aaggctttca
      241 aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag atattatcaa
      301 ttgaatccca attaaactta tggatatctg ttgtgaactc ttgaataggt ttggtggtat
      361 ttatgttatg gttcaaatcg tgtgacttac tttcaactgt gggcgcttga ttattcacat
      421 tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca gcaagcatag
      481 ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat atgtacctaa
      541 aaaatactaa caatagaaat ataaaacaaa agcttactac gctcattatt agtaatttag
      601 ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat attacaattg
      661 taatattatt gatttataaa aattacaact gtaatatcgg agggtttatt ttgaaaaagt
      721 taatattttt aattgtaatt gctttagttt taagtgcatg taattcaaac agttcacatg
      781 ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt tatgctttaa
      841 atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc tatgcttcga
      901 cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat aagttaaata
      961 aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta gaaaaatatg
     1021 taggaaaaga tatcacttta aaagaactta ttgaggcttc aatgacatat agtgataata
     1081 cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa
     1141 aagaactagg agataaagta acaaatccag ttagatatga gatagaatta aattactatt
     1201 caccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact ttaaataaac
     1261 ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat ttaatgttta
     1321 ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat aaggttgctg
     1381 ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt gtttatccta
     1441 agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat aaaagtgata
     1501 agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt
     1561 ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt gtattatcgt
     1621 tgacatgtat aattttgata tcaaaaactg attttccctt tattattttc gagatttatt
     1681 ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat aaataataga
     1741 tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta tttaaagtgc
     1801 gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa agtgacaata
     1861 gcattttaca agtatttttt attgttcgat tagggtaaac ctaaataata cataaattat
     1921 attacaatat gtttattata gaggctaaag tatcttagaa atttggatag taggtttttc
     1981 gggaataaaa gtatagttgg ctttaatata taattaagct aagctatcat ttatatttac
     2041 tcgattataa ttcgcacttc aactttttta taacgtaaaa attaaaacgt agttttattt
     2101 atctttagta atatcttttt aaacactaca gtttcttcat tagttaaatt agcgaagtaa
     2161 tgattattaa gttgataggc tttcttttct aatgttggcc ataagtcttt tgctttattt
     2221 gtactgttta ttagcacagt tcttctattt tcattatcag tttgacgtgt tattagatcc
     2281 tttttggaca tcttatctaa tattccagat attgttgaag gttctaaatt taaagtatta
     2341 ccaatcgctt taggtgtatt caaattacta ttaatcaagc aattcaaaac accatattct
     2401 gctggagtaa tattataggg acttaataaa cttttaaaat gtttaaaaac tctattctga
     2461 gaagtactca acaaataatt tatacaatta tctaattcca caactaaaac ctctcttaaa
     2521 tcattagtat tgactcgctt atcatatcat gataagtttt gtaggaaaat agttttgcaa
     2581 caaaaacata cttctacaaa acaattgtga aagaaggcta ataaatgttc aatgcggtag
     2641 tagtgagaaa aagtgcatca aatgttagtt ataaagtaga aaaagttgat gaatctcatt
     2701 tatcgaaggg tgatgtatta gtaaaagtgg tatactcttc aataaattat aaggatatgc
     2761 tagctttaca atataaaggc ggtgtaatta gagattatcc tatgattcct ggtatagatt
     2821 ttgcaggtat tgttgaatca agttcgaatg ataagtttaa agaaggcgat aatgtattag
     2881 ttactggtta tgatgttggc gtgacacata caggtggatt ttcagaatat gcacaagtgc
     2941 ctggagagtg gattgttcct attccccaag aaatgtctat taaagagtct atggtatatg
     3001 gcacagccgg ttttacggca gcattatcaa tttttgaact agaaaaatat ggaatgaata
     3061 tcaaatcaca acctgaaatt ttagtgtctg gggctacagg tggtgtgggc agtgttgcta
     3121 tacaaatttt acataaaatt ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc
     3181 aaatagaaat cgcaaaaaaa ttaggtgcaa aacaagtaat aataattgaa gatgataata
     3241 aaccgcttaa aaaaggtatt tttgattatt tcttagatac agtggggagt aatgtaacat
     3301 tatacggttt aaaacgtcta aattatcaag gtgttgctac tgtatgtgga aatgtagcag
     3361 gaaattcact taacgctaat atattaccgt ttattcttag aggtattaaa ttaattggca
     3421 ttgattctgt atatgttgat cataatatcc gtgaagatat atggagtaag ttagcaaatg
     3481 aatggaatat aggaaattca cttctataca atgaaattgg atttgaagaa ttctataaaa
     3541 cgatagatca gcttttaaaa ggacaacatt taggaagaac tattttaaaa gtataagtgt
     3601 gagtattcat taatacattt actattaatt caatcatttt gcatttctct actaaccagt
     3661 gttataattt atataacgaa aatgattaac aattaatgca ccaatcccca cactattgca
     3721 gtagtgtggg gattttttcg atgctggctt ataaagtcgc ctattaatta tttgttgcgt
     3781 ttactaagcc aataagtata atacgcaaca gcacagccac tgatgactgg tgctatgatg
     3841 tgaacgaaaa tgattagcaa agtaatgcac ctcctctctt cgtcaattga cgcctgagag
     3901 ataggcgact ctattattat accatctgtg aatatacaag catatctact tccgataagt
     3961 cgtcttatgt tatataactt tgttttttat agtatcaaga caagaagaaa ctcgtttcaa
     4021 aaaccctcat gatttttaga gaaaaactct cttatttcat cgtctttaat aaaataatat
     4081 gccatctttc catctttata aaaatcaagt acctcatttt tatataaaag ccttaaatga
     4141 tgtgaagttg aagcaacact cattttcaat atcaaagaaa tatcacaaac acacaactca
     4201 tcttctttaa tcaaagataa tatgattttc aatttcttct catcacaaat tttttctaaa
     4261 atgttaagta atttcttaga tttatcatct tctaaaaaac ttaaagcatt gttaacttta
     4321 tcctcatgta cacagatcac atcacaagta ttttcataac tcatataaaa tcacacccta
     4381 aattaaaata taaatcctaa aattgtttga atagtgtcat tttcaataat aataaataaa
     4441 cctaaagcta tataaataat agccataatc caacgactaa atttctcaac aatttctcca
     4501 attcctggaa tattagctaa tttttgtgca gtaaacacca agaagaaaat taaaattaaa
     4561 aagacaaaca gagtaagtaa taaattagta acacttaatg tcacaaaata cggaacaaat
     4621 aaaccaatat tatcggcgcc acaacttgct atcgtaacaa ttgcaaccgt accaactaat
     4681 ttagacaatc ctttttcatt caattctttt ttagctctct tttctccttc acaatcatca
     4741 taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc taatatccac
     4801 ttttctggaa cataatttaa tacaaaagct aaaaacaaac taactaatat taaaataata
     4861 gaccctaaat attgaccaac ataaatatct ctatattctt ttctagtctt tgctctagca
     4921 aaaaatatta ataaaattac taataaatca actgctgtag caatataaag aacagcagca
     4981 gcaacaaccg tttgaatcat aatacacctc attcaaaaat atttttgaat gtattataac
     5041 ttatattttt aaataatcat aggtgcttta ttccaattgc tttattgacg ttgagcctcg
     5101 gaacccttaa caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctatgccga
     5161 cattcgtctg caagtttagt taagggttct tctcaacatc aataaatttt ttcggcataa
     5221 atgcgtgtct atgcgtagac atggagacac ttcagaatta tggagtgatt acatgagttt
     5281 aactattttt ctttattcag ttttaggaag tttattagca aattatatct acgaaaaatc
     5341 ttcaaaataa ataacttttt cggttctact ttgtacactt tatctacctg gtagacctaa
     5401 ttgttattgc tttacaggtc taaaattcgt cgttataatc tagttaaatc ccgtaagggc
     5461 gcacttatac gtcggataaa tcgacatgtg caaaaacgta atcgaccttc gtcgattttt
     5521 ttatttcaaa attaaagaaa cggcttgaga tattccgagc agttataaaa attaatttgc
     5581 gttgaatatt gctactacat tcttgaaaaa gtgatgtaga tttatagccc ataacttttt
     5641 tgaattacat cgacgatacg gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag
     5701 ctacctcact ttatctgggg tagcttttat tttttatgcc cttattttga attttaagag
     5761 ggcattttaa agatttaggg gtgattcata tagttttata tctaaaactt atatatgctt
     5821 ttaaaacgca aatatgagcc aaataaatat atgctatttt caaaaacaaa aatttgagca
     5881 aaaacaataa ctatttttag acactgccca tttacatgca aattaaaaat tagcataaaa
     5941 ttctttaaaa cttccccacg tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa
     6001 gacaagaaga aactcgttca cactcgtttc aaaaaaacaa gaaatctaat ctatacacct
     6061 accgttttcc aaccccctca aagcatacaa attaaaaaca aaattattca taatcttact
     6121 ttcttttaac aaaaacataa aaaccataaa tagacaaatt aactatcaaa ggcaataaac
     6181 agtataaaaa aaccacgaat aaatcttcat caacatctaa aataaaaaag aataaaacaa
     6241 ttaacaaaat actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat
     6301 tttcattcat aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat
     6361 tgattttata aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa
     6421 tgaaaattat aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt
     6481 tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa
     6541 aattgaaaag caaaaacatc gaagtatcac aaatgaccaa gaaagaaata agttttctag
     6601 aacaattgca aaataaaaat gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag
     6661 gatttaaaaa aataaagcta gaagacaaaa attctaaatt aaaatatcta gctacagaag
     6721 caaatgataa aaatgcatat ggctacatag ctaataacgc ttataaaaat gaaaaaacaa
     6781 aagaaattgt agtttctgaa acaatatatg ataactacaa caaaaaaatc acaaaattca
     6841 ttgccgaaaa aagaagtatg actgaaaaca aagagggaaa aatacttatt aacaaaaatt
     6901 acgttgaata taaggctgaa aaagttgata aaaacagacc ggtaacatat gcaggattca
     6961 aatggaacgg caaagcattc gcttgtagta tggctggact ttatgcatgt gctcactact
     7021 gtggagtatg ggcaatcgta aatccaatag ccggcggtgt atgtgaagca gtttgcggaa
     7081 ctgcatttgc agctggatgc tctgtaggtt gattttattc caattgtttt attgacgttg
     7141 agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat agctcacgct
     7201 atgccgacat tcgtctgcaa gtttagttaa gggttcttct caacatcaat aaattttttc
     7261 ggcataaata cgatgttcct tatttatcct cataaaaaac aatagctgaa atatataacc
     7321 aattactgtg tgtttgaatt tctaatacat gaatatcatt ctttaaaaac ctattaactt
     7381 gtttatctaa ttgacgatga gtaaaagtag cgaaagtttt aatcttcatg atatctctcc
     7441 ttttataaaa atagcaatcc ttattacaat attaaacact tttattttgg attttaagag
     7501 gcattttgaa gacttagagg caaatcatat aggttttgta cttaaaaatc tatacagtct
     7561 cttaaaacgc aaatatgagc caaataaata tatgctaatt tcacaaacaa aaatttcagc
     7621 aaaatcagtg actaattttt tagatactgc ccatttacat gcaaatttaa aaattagcat
     7681 aaaatacttt aaaacttccc catgtttttc taaattcctg cagggctttt cttatcaaaa
     7741 acttagaaat tttaatttaa ctctaaaatc tccgtaagag cataagggaa atttgctatc
     7801 attcaaaaat gatagatctg gcaaggccag acattccaag ggttttaagt tattttaaag
     7861 tgatatcata caaagctgta gtgtcacact tttgtgacac tacatacagc atttgtcaca
     7921 aaaataagac agcacttttt tacagaaaaa caataaaaaa agacatcagt tatcactaat
     7981 gtcttaaata ataattttgc ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt
     8041 tcttcgtctg tcgttttatc ttcatcactt gtattaatca aattaccatc ttcggcatcg
     8101 tctaagttta aaattttatg cttttgttta agcaatccac cataacttaa catacgtttt
     8161 cgatacaaac ctttttctaa atcacttaca atttcttgat ttttttcgtc gtcatcagtt
     8221 aaaaagtcag atgatttaac ggaatatttt gatgtctctt cgagtgttat aaaatcattt
     8281 gaattattga ttaaagatat tatattgttt catgttttta cggcgcatat aaagggcatg
     8341 tgtttcttca agttcagtta gaattgtttg cattaaataa gcttgcattg acttgattgt
     8401 ttccttttgg cctttaactc ccctatcatg tatagctttt ttaagtcttt ttaaagaagt
     8461 taatatttca tcctcaatgt cctctaacat gtaatgcata tcttcatgcc ttgaattaaa
     8521 tgattttttt gctttaagaa taacagcctt tatgatttct aaatctctat aatcatattt
     8581 taataaataa ttagttagtt gttctgggaa ttcttgcaat agcatttctt tatcatcaaa
     8641 attatgtgta aattgatttg aatgatttga atgattacta atttcatttt tgtactttat
     8701 atcattcaag tcattcatat cattattctc agtatcatta aagtcaatgt cattaaagtc
     8761 agtatcatta gtgttcgatt ttcgaacttc tggacgttcg attttcgaac ttctggacgt
     8821 tcgattttcg aacttctgga cgttcgattt tcgaacttcc ttctcgccgt aaggttcaac
     8881 atcgttttct tctttttcta ttttgtaaat atcacgttct gtgacaatag gtttcattaa
     8941 atatagaata tttggtttat ttaaaccacg tcgtttttga atgagtagac catcgttttc
     9001 taaccctttt tttatttttg ttaacttttc ttttttacaa tttaagattt ccattagctt
     9061 ttcatttgaa taaacaaagt aaatgttacc atcttcatca acccagctat ttttaataga
     9121 taaatttaag cgatcacgta agatagcata ggctattttc atatcattag ttagattttt
     9181 ataattttca ctggtaaaga atactttagg gatttgataa aatctttctt tgtaattttc
     9241 ttgcactgta aaatattgat tttgcatgac aaaaaacctc tttccatatt ttagtttggt
     9301 aagaggtaat aaaacgtttt tatttagctt tacatttatt taatgattta ggtgcttgca
     9361 ctaagatatt attcattata taatacaagt atcgaaaatt atataaataa acagtttcta
     9421 aacgttttat taccaaaccc cgactattac cagtagttgg ggtttttgtt atattaagtt
     9481 tattatagca ctttaaataa acttataaaa gggaaaatat agctttatca agggtttata
     9541 aacccttgat aaatatcata aacctttcat aaacccttga taaaaaggtt gatggatgtt
     9601 tatttttatt tattaatcac tttattatta agcattataa gcttataata ttttatcaag
     9661 ggtttataaa cattttataa agggttgatg atatgaaaag tgtgaaaaag ttgagtgaag
     9721 aattaggggt tagtaagcaa acgattttta ataatattaa gcgattgaat atagagacaa
     9781 taaaacagga aaacacttcg tttattaaag aagataccga tatagaaaaa atcattcaaa
     9841 gagtaaatga aaataaaaag aaatatggtt ttgaaagtac tactgaagac aaacaaaaaa
     9901 aagggtcgga taatattaat tttgaatcga aaagcgatgc tcaaatagta gaaatcctta
     9961 aaaatcagat tgatacttta aataatcaaa ttgaaaaaca agaaagtcgt catgaaacaa
    10021 caattgaatt ttacagaaaa gagttgcaag aaagatcaaa attgcttgaa aatcagcaag
    10081 ttctggcatt agagagtaat aaaaagattc aaaaattaga aaatcaatta gaaaaagaaa
    10141 aacaccttaa ttatcccttt gatacatcta ctaacactag acaaaacgtt gatgcacaag
    10201 aaaaaacata tactactaat cctgtaaata ttaacagaga tcaggaagaa actaaagaaa
    10261 cagagattca atataaggat atatctggaa gtcaaagcga cgaaagtaca caaggtgaag
    10321 aagcaaaaaa agaagacgtt ccagctaatc taaatgacaa tgatagtgat atagaagaaa
    10381 agagtgaaga aacggaacct aaaaaggggt tttggagtcg tttgtttggt agctaaaata
    10441 attgattagg cactaaaagt tataaaattt tagtgtcttt tatatagtga gaacttctgg
    10501 taatcatcga ttatgttaac caaacaaaaa gccataaatg ccttcatata ggcatttatg
    10561 gttttttact ttcattatct tttatgcatc ttttatacat cgttgatttg acgcgttttc
    10621 attcttttgc attggcaagt attttgtatc tttattcagt tactatttct tttctccaac
    10681 ctaacaaacc atctttaact ctaataatat gtttgccacg ccaggcactt cttacttcga
    10741 aataatacca ttccccgttt ttgttgagga aataaatatc ttgataacct tctttaatga
    10801 catattttgt agcttcttgt ctttgatcgc caaacattat caatcccacc cttatattta
    10861 tttatcttta atatataaca acatttatta atattcatgt tatttcatgg aagaagagat
    10921 ttgttataat gtgaaggtcg tctatctctc agacgtcaat tcggcgtaga gaggaggtgc
    10981 gatttatgaa tgaaattctt gttcacatca tgacaacggc aatcagtggt tgtctcgtta
    11041 cgttatttgg ttattggctc cataaacgtg ataaaaaata atatagacga ttaaagccaa
    11101 ttcaccaaaa aaccccgaac tacggcgaat agttcggggt ttggtgcgtt tacaaacgaa
    11161 attcttgtta cttttagtat atatttcata ttgccttttg taaactcttc tattcttatc
    11221 aatacatttc aaggtgtcgt aaaaatactt tcctttttca tattgcctga tgtgcattaa
    11281 attttgattt taaaatcaac ccatgaacga atgaatggcc caaactaaaa atccggcaac
    11341 aggaaagaaa agccaccaaa aatcataaag aaaatcaact atggaaggtg ccctgttact
    11401 ctctctataa tttccctcta aaataacttt tttaaaacgt gcatctcctt taattaaatg
    11461 ctctaaagag attccaaata aatcgctcat agcaatcaaa atatctaagg aaggatagtt
    11521 tttggcactt tcccatttag aaacactttg tctggaaacc tttaatatat tggctaattc
    11581 ctcttgagac catcttttta attctctctg ttcttttata gcttcagcta atttcataaa
    11641 atcactcctt aactcaaact ataattaaaa taattgaaaa gtcacgatac ttttagttaa
    11701 ccaactcgca acgaaaagtt gcgttattcc caattcagtt caagttgttt taaaaaatcc
    11761 tctcgttctt tctctaattg tgggtcgtaa tctttttgag gttgcttttc atatgaccgt
    11821 tcttctaacc atttaggcgt cttttcacgc ctcacatatt gtcttgattt atctatcttg
    11881 gacatttgag gttgtcgttt gttatgaatg cgtttctcag cgtcaaatgt gaactctatc
    11941 cattcaattt tacgcccttt tttagctttg attttattga tagtaagatt attaaatata
    12001 gaacctaatt caataataat aggtttaaaa acatttttgt taatatcagt catacgataa
    12061 gatttaggta tatctaaacg atttttaaaa tcatcgatgt gaatttttaa atagcctgta
    12121 tgtttgtatt gtttaagtaa tctaaacata tttttagaat atgtagattt aagcctagtc
    12181 atttctttta attcaaattt tgtaaaatta ttagtaattg aattcaatat gtgttttaaa
    12241 tttgaagaag ttgatatttc tagatattgt tctcgcttat ggattctata atgattgaat
    12301 aaaacgaatc tttctattac atcatcatct tcatatctaa tggttaaatt caacatcttt
    12361 ttatacacat tatctaaatc attagcaaat ctattaatat tacgtgtttc tggactataa
    12421 ttacttaatt tttttaattc atcaaaagac aaacgtaatg tattagtatc ttgctctttt
    12481 aatttattac acatcgcaaa aaataaatta atttcagtag ctgtaaatcg ccttaatgga
    12541 actaaattca tttcattttt atatacaact gtctctcctg tcatgataca gccccccttt
    12601 attacgaacc taaaggagta tcgtttgaat atacactccc atttgaaaac ttttattcac
    12661 aataaactac tttattatca atgtcaaacc ataaaaggag tacaactttt taaaacaccc
    12721 cttttatgtg gcaaaaacac tcctttaggc attgaaatcc cttgttgctc taggtctgaa
    12781 caagccccta aaagattttt aaaaagattt ataaaaatat attaaaaagt tagagggggg
    12841 ctacctattt ttcatcctaa aaaataatta acctcaaaca aatgcattta aatatctatt
    12901 tttataatgt ataaccatct tctctatctt ctttaaaaat gatttctcat tcttgtgctt
    12961 gatatttctt cttaaagaac tgttcatcat tgttatctat cgtcattact tcacgtattt
    13021 tagaattgtc taaatgatta tcaatatgat ttattagcgt atgataacgc tcttctttca
    13081 tcatactttt aatgatttta aaaacttgat tgaataactt aagcgtataa tttagttctt
    13141 tatctttctt ttcattctct gacaacaaat aattataacg ttgtgctaaa tcattaaatt
    13201 cttcaaccag cttttcattt tccatatgga cactagtcaa ttcattaact aaactttcat
    13261 tttgtttctc tgattttttt aatgacttcc cacttttaat ccattcataa tcatctaata
    13321 tcatctgtgc tgctttaatt tgtttagtgt atttttcaaa ataagtttta gtaattacaa
    13381 tattgcctgt ttcttgcttc tctttatgaa accatccacc tacattttta gttttaattt
    13441 catacatgac actcagaagc tttttaagcg tatctaatga tttttggtag ttttgtatca
    13501 atttatcatt ttcttacttt aaatgatcct ctatttgctt ctcgcgcata tacatttgtt
    13561 tatgatattc tgttttttgt ttatagccgc taacttgatc atgtttttct tttgtaagtt
    13621 gtctagaaat tcctcgtttt aaatcatagc cttgcttatt aatatacgta ttgaatctat
    13681 cttggaattc ggttaatgct tttttattac ctacaacttc tttcgcactt aaacgtccat
    13741 ctttagtaat aggaattacg ccataatgca tatgtggtgt tatctcatcc atatgtactg
    13801 tcgcatataa aagattttct ttaccgtatt cttcttccaa gaacgcttta gcatgcttaa
    13861 aaaactattt tgtctcttct tcagataatt gattaaaaac acattatctg atgtaattaa
    13921 tccatcaata tgtttaatgg catctgttct aattttgcgt ttccctttat aattttgttc
    13981 gattttctca tcaatttttt tattaaaatc aaacttagta tcattgacta aatcatagtt
    14041 taaatatgac ttacttaaat caatatctat attttcataa tttttatttt ctctttgaat
    14101 acctcttgta tttgtttttg atttcacttt aacaactcga ataattgaat aagacataat
    14161 aaatcaactt ccactgcata tgattataac acctaaacac agaaaagttt taacatacta
    14221 gacttattaa aaaccaaata agtcattaaa aacgtgtgct ctgcgaggct tgttttttgt
    14281 catcacaaaa aaggactgga aaatccagtc cttaaattaa aaaactcaaa agtaatgact
    14341 aatcatattt catattgttt tttctctatg tatggctata cctatcaata tttcttaact
    14401 tctaagctca gaaatattga ctatgacatc aaatcgtttc gcaagctcta aatcatgcgt
    14461 tacgacaatc atagttttat tttcatcaag tagcttcaat aataaatcaa taactatttt
    14521 tccatttttc gtatctagtg atccagtagg ttcatcagct aaaatgattt tcggatcttt
    14581 taatattaat cttgccaatg ctactctttg ttgttcacca ccgcttagag aactaacaat
    14641 tctcttgata tctaaatcta ggccgacctt ttttaatact tctttcttta agttcatatt
    14701 atctttttta ttctttttga actttagggc taaatctaaa ttttgactga ttgtttgatt
    14761 ttcaagtaaa gcaaaatttt gaaacaaata ccctaacgta tatctataaa aatcgacttt
    14821 cttttttagt aacttatctt caatatatat gcttccttgt gatacatctt cgaacccagc
    14881 gattatgtta agtaaagtag attttccagc gccactttct ccaactaaag catatgattt
    14941 tcctttttca aaattaaagt tacatccgtc taaaatgttt ttattacctt tttttacaaa
    15001 aacattttca agttttatca ctatcggtca cctcatttta aaaagctagg aatatctttt
    15061 gtaatgtatt ctatcgaacg cacatatttc cctttatgat ttactttcac atattctttt
    15121 gtaggatcat aacctaaaaa atccaattta taactctttt tttctccatt tttagagtat
    15181 acagttatat ttctatagtc ctgggtatct tttggaactt tggcataaga tactttttct
    15241 tttaacagtg ggttaaaacg atctaaatgc tcatttctaa ccaataacag actaagtatg
    15301 atgattaata gtacaattgt tacaataatt aaagttcttt tcattgttta aatctccctc
    15361 attaaatctt taaagtattt ttcaagatat ttaatataag caatttgaag taaatgttga
    15421 ataatagcaa tagacattat tatgaatagt aatatctttg aaccaaataa aatatgcgta
    15481 gtgtaagcta acataataga aagtaaaata gaaattgtta aataacgtac attactgctg
    15541 aataatgaat aaccatgaat ttttcttaat aatagttgct ttttattcca gctaaaatat
    15601 tgaattgttt caaatacagt agctatcaaa agaatgaaaa cgttaataat aatagtaact
    15661 attgttatta tcatttttgt tttcgtttca tttaattcat ttaacacaga atccttgtaa
    15721 ttagttatac cgctaatttc ttcttctagg tgattatctt taagcaactg tttaagtgta
    15781 tctaaatctt taaatagata tccaccttga gaaacagcag ctaaataaaa atctcctgtt
    15841 aaatcgtcag gtgtcaacaa cattactatt ggagaatcta gatatccaaa tttcaaatta
    15901 gttgtgcgat caaaagaaaa aacagatacg ttttttgaca gtacttgcac atctactttt
    15961 ttgttttgtt gcttttgaaa gtcaatccat ccttggtgat ttttttgaat ttcagatttt
    16021 tgatattgta accttggagg aataaacacg tttattttat ccgaatgatt gtcaatcatt
    16081 ttaaaatcat gatttatatt tttatagaaa ttcagaaaat tgttattgat aaaaaagaca
    16141 ttgccatttt caggaatgta attgttttta tcgggattgg ctatattatt attctttaaa
    16201 agcaatccac caagttgttc gcttttctta attaaattgt atatattagt ttctaaaatt
    16261 tgtttttctt ctgaatttct aatattagga gaaatctcta atgtatagta attatctaac
    16321 ttttgccaga ttttttcaga gtcatatata ttctttaact tcgtataagc atttaaattt
    16381 tgtgccagta aaaaagatag tattagcacc atgatacatt tggtgaaggt acccataaat
    16441 attgaaaact tatatccttt tttccctttt aaggttaatg gaatacttaa cttcaaaaga
    16501 agactatacg aaatcagcca caacaatgta gtaatacaag caaaaacaaa aagcaacacg
    16561 ataaatctac gaataaacat taagaaatcc aattctaaat tggctatatg aatgattaat
    16621 atattagcaa taaagaaaat agtggtaagt actagccaat aaatgatttt tatatgaata
    16681 ttatgaaaaa taatgcgtgt agttgaaaag ccatgtagct tttgaatagc ataaaatttc
    16741 aaattatatc ctctgtcata taagaagtac aaaagatata atacgcctaa gaatatgaaa
    16801 ggcactaata aatcattatc tatgactaat tcaaaaaata atatgtttct atttatgtat
    16861 tcaacttcag atgttaaacc agcttttttt aattcactcg taagctcttc tacattgaaa
    16921 tgttcaccaa taatataata ctttcctttt atctctctgt ttaataaatc tgatggagtt
    16981 aaaagtgatg ttttattacg tataaagtca gaattatttc gttttgagtt gaaaacaaaa
    17041 aattcttttt tattatcaaa atctttaacg gatttaatta tttgtatatt ttgatttttg
    17101 gcgcctgatt caatgacatc taacactttt gatttactgt tagatttatc ccaattagag
    17161 attgttaaaa tattggaact ttcaggtata atttcttcat tttctttgaa gaaaaataaa
    17221 aataatagcc ctgaaattaa taataaagta ctaaaatcta aaaataattt gaattttttc
    17281 atattgcctc tttcaagaga atagacagaa ttaagtttac ttaattctgt ctattctcct
    17341 taattaatat atgtaattag tgaagactat aaaatgtttt gtttccaccc caagcctttg
    17401 gagcagatgc cttagattga acaccaggtc gagcaacacc actaaaagat gaatatttcc
    17461 ctactgctgt tgaaccatga tttcttttat tgtgactata ataagaccat acgtaatgtt
    17521 ttccaatacc atggctccaa acaccaccag ctacatgtac tgttgcagct tcagctttat
    17581 aagttacacc taataaagtg ccgaataaga ttgtactagc aatacaacta gaaacaaatt
    17641 tctttttcat aaaaacaact ccatttaata ttctttattt attatagcaa aaataaataa
    17701 aatagagaat gagtaaaaat aatctaaaag tgtttttttg ctctgttgct tgttttgttc
    17761 atctat
//
