LOCUS       CP127555               20719 bp    DNA     circular BCT 19-JUN-2023
DEFINITION  Staphylococcus aureus strain C905 plasmid pC905_1, complete
            sequence.
ACCESSION   CP127555
VERSION     CP127555.1
DBLINK      BioProject: PRJNA914892
            BioSample: SAMN32360957
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20719)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Hybrid Oxford Nanopore Technologies Illumina Sequences of 174
            Staphylococcus Aureus Isolates from Chronic Rhinosinusitis Patients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20719)
  AUTHORS   Bouras,G., Houtak,G., Nepal,R., Shaghayegh,G. and Vreugde,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUN-2023) Department of ENT Surgery at the Basil
            Hetzel Institute, Adelaide Medical School, The University of
            Adelaide, 37 Woodville Road, Woodville South, SA 5011, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-NOV-2022
            Assembly Method :: Flye for Genome, plassembler (Unicycler) for
            plasmids v. 2.9.1 (Flye) with short read polishing, 0.1.1
            (plassembler) with 0.5.0 (Unicycler)
            Assembly Name                     :: C905
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/11/2023 01:47:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,656
            CDSs (total)                      :: 2,575
            Genes (coding)                    :: 2,508
            CDSs (with protein)               :: 2,508
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 33 of 67
            Pseudo Genes (incomplete)         :: 30 of 67
            Pseudo Genes (internal stop)      :: 21 of 67
            Pseudo Genes (multiple problems)  :: 16 of 67
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20719
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="C905"
                     /isolation_source="Patient Sinus Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pC905_1"
                     /geo_loc_name="Australia: Adelaide"
                     /lat_lon="34.9285 S 138.6007 E"
                     /collection_date="2019-08-30"
                     /collected_by="ENT Surgery Department at the Queen
                     Elizabeth Hospital, Adelaide, Australia 158"
     gene            166..842
                     /locus_tag="PCM67_13160"
                     /pseudo=""
     CDS             166..842
                     /locus_tag="PCM67_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            853..1135
                     /locus_tag="PCM67_13165"
                     /pseudo=""
     CDS             853..1135
                     /locus_tag="PCM67_13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology. GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006260 - DNA replication
                     [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2336..2953
                     /gene="cadD"
                     /locus_tag="PCM67_13170"
     ARG             2337..2950
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2972..3319
                     /locus_tag="PCM67_13175"
     CDS             2972..3319
                     /locus_tag="PCM67_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_function:
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WIZ47987.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3488..3580
                     /locus_tag="PCM67_13180"
     CDS             3488..3580
                     /locus_tag="PCM67_13180"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WIZ47988.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3792..4316
                     /locus_tag="PCM67_13185"
     CDS             3792..4316
                     /locus_tag="PCM67_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WIZ47989.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKN"
                     /name="DUF4062 domain-containing protein"
     gene            4361..4765
                     /locus_tag="PCM67_13190"
     CDS             4361..4765
                     /locus_tag="PCM67_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WIZ47990.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIK
                     GLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="hypothetical protein"
     gene            complement(4885..5700)
                     /locus_tag="PCM67_13195"
     CDS             complement(4885..5700)
                     /locus_tag="PCM67_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WIZ47991.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5693..7136)
                     /locus_tag="PCM67_13200"
                     /pseudo=""
     CDS             complement(5693..7136)
                     /locus_tag="PCM67_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(7108..7701)
                     /locus_tag="PCM67_13205"
     CDS             complement(7108..7701)
                     /locus_tag="PCM67_13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WIZ47992.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7965..8345)
                     /gene="blaI"
                     /locus_tag="PCM67_13210"
     ARG             complement(7969..8345)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8335..10092)
                     /gene="blaR1"
                     /locus_tag="PCM67_13215"
     ARG             complement(8339..10092)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10199..11044
                     /gene="blaZ"
                     /locus_tag="PCM67_13220"
     ARG             10200..11041
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11413..12021
                     /locus_tag="PCM67_13225"
     CDS             11413..12021
                     /locus_tag="PCM67_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0000150 - DNA strand exchange activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WIZ47996.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12435..12728
                     /locus_tag="PCM67_13230"
     CDS             12435..12728
                     /locus_tag="PCM67_13230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WIZ47977.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12803..14737
                     /locus_tag="PCM67_13235"
     CDS             12803..14737
                     /locus_tag="PCM67_13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WIZ47978.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14741..15052
                     /locus_tag="PCM67_13240"
     CDS             14741..15052
                     /locus_tag="PCM67_13240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WIZ47979.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15064..15690
                     /locus_tag="PCM67_13245"
     CDS             15064..15690
                     /locus_tag="PCM67_13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WIZ47980.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15928..16557
                     /gene="mobV"
                     /locus_tag="PCM67_13250"
                     /pseudo=""
     CDS             15928..16557
                     /gene="mobV"
                     /locus_tag="PCM67_13250"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16651..17196
                     /locus_tag="PCM67_13255"
     CDS             16651..17196
                     /locus_tag="PCM67_13255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WIZ47981.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="recombinase"
     gene            17580..18440
                     /locus_tag="PCM67_13260"
     CDS             17580..18440
                     /locus_tag="PCM67_13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WIZ47982.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18527..18868
                     /locus_tag="PCM67_13265"
     CDS             18527..18868
                     /locus_tag="PCM67_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WIZ47983.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19107..19178)
                     /locus_tag="PCM67_13270"
     CDS             complement(19107..19178)
                     /locus_tag="PCM67_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WIZ47997.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19327..19512
                     /locus_tag="PCM67_13275"
     CDS             19327..19512
                     /locus_tag="PCM67_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WIZ47984.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19731..20474)
                     /locus_tag="PCM67_13280"
     CDS             complement(19731..20474)
                     /locus_tag="PCM67_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WIZ47985.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10200..11044
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7435..17728
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17581..18440
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19732..20474)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15929..16203
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atgctgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttagacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1621 aaaataaggg cataaaaaat aaaagccccc ccagataaag tgaggtagct ttttctttcg
     1681 acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc
     1741 aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa
     1801 gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg
     1861 tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat
     1921 tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga
     1981 accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct
     2041 aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct
     2101 ccatgtctac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac ccttaactaa
     2161 acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg
     2221 gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag cacctatgat
     2281 tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt gtattatgat
     2341 tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt tattagtaat
     2401 tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata tttatgttgg
     2461 tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt ttgtattaaa
     2521 ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt atcttggaat
     2581 taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaag aattgaatga
     2641 aaaaggattg tctaaattag ttggtacggt tgcaattgtt acgatagcaa gttgtggcgc
     2701 cgataatatt ggtttatttg ttccgtattt tgtgacatta agtgttacta atttattact
     2761 tactctgttt gtctttttaa ttttaatttt cttcttggtg tttactgcac aaaaattagc
     2821 taatatccca ggaattggag aaattgttga gaaatttagt cgttggatta tggctatcat
     2881 ttatatagct ttaggtttat ttattattat tgaaaatgac actattcaaa caattttagg
     2941 atttatattt taatttaggg tgtgatttta tatgagttat gaaaatactt gtgatgtgat
     3001 ctgtgtacat gaggataaag ttaacaatgc tttaagtttt ttagaagatg ataaatctaa
     3061 gaaattactt aacattttag aaaaaatttg tgatgagaag aaattgaaaa tcatattatc
     3121 tttgattaaa gaagatgagt tgtgtgtttg tgatatttct ttgatattga aaatgagtgt
     3181 tgcttcaact tcacatcatt taaggctttt atataaaaat gaggtacttg atttttataa
     3241 agatggaaag atggcatatt attttattaa agacgatgaa ataagagagt ttttctctaa
     3301 aaatcaggag ggtttttgaa acgagtgaaa cgagtttctt cttgtcttga tactataaaa
     3361 aacaaagtta tataacataa gacgacttat cggaagttat ctatcatcgt atattcggag
     3421 atgatataat atacaggtcg cctatctctc aggcgtcaat tcagacgcag agaggaggtg
     3481 cattactttg ctaatcattt tcgttcacat catagcacca gtcatcagtg gctgtgctgt
     3541 tgcgtattat acttattggc ttagtaaacg caacaaataa ttaataggcg actttataag
     3601 ccagcatcga aaaaatcccc acactattgc agtagtgtgg ggattggtgc attaattgtt
     3661 aatcattttc gttatctaga ttataacact ggttagtaga ggaatgcaaa aagataatat
     3721 tttaagtagt ctttttggat attatcatat gatatattta tgtaaattga ttttttatta
     3781 aaggagcata tatgagtaat actaaaatta aatatcaaat ttttatttca tcaacttatt
     3841 tagatttaat agaagagcgt caagcagtag tagaagcagt tttaaacagt aataatattc
     3901 cagcaggtat ggaacttttt aactcaagta gtaaaagcca atgggaaata ataacacaat
     3961 ggatcaatga atcagatgca gtgatattat tgttaggttc tagttatgga acaattgata
     4021 gtgaagaaaa tattagctat acagaaatgg agtacaattt tgctaaatct ttaggtaaac
     4081 ctatatatgt ttttgagatg aataaagcat ctaccgaatc cgcggaaaag tctaaaaaat
     4141 tagatgagtt taagacaaaa gttaaagaaa atagactaat tagtccaaat attaatgata
     4201 tttcggaatt aaaaagtaaa gtatctcaga ctttaatgca aagtgtacct agtgaaatta
     4261 aagaaaatag tggatggata agagtacagg attgtggtaa aaatgtaaaa aattaaaaaa
     4321 attggatgct atacaaagag atttagatac atatgatttt ttgaaagaag aactttataa
     4381 aatattcatg tatgtaaaaa ctttttattt ccagcacaca ccatttgatg atagttatat
     4441 tgaagatata gaaaactacc tgctaaatta tgaaaataat ccacataaat cattcatgaa
     4501 aataaaagtt tatgattata aaaacttttt aaaacattta aaaaacatat tgattttaat
     4561 taaacaagga aaaaagccat tagctcaagc cggtcatttt aaattaagct tttacgaaga
     4621 ggatttaaaa ttgttacaaa aaaattataa gactacgcta gtcgatatta aaggattgaa
     4681 taaacatttt tataaggaat gtgataggtg cttaaaagca tataatattt ttattgaggg
     4741 tataaataaa catttatatg aatgatataa gtacacccta atcatacata tataattgtt
     4801 gtcactttac tcgatatatg agaatgactt tacctaataa atgagaaaag caacgcacta
     4861 tattaaaatg cgttgctttt tctattatcg aatacctata actaaactat ctctagctgt
     4921 ttctacaact tctgtactta ttttatctaa accatttata tccataattc tgtctatctg
     4981 cgcaaataaa cgatgaatca gcctaaaatt cccttttgta attttaataa tcgtcgttat
     5041 tgcctcataa tcagtaaagt cttcgagttt taaatcaaat cctaagtctt gccacttata
     5101 ttctaatata tgatgcgtct catctttact tagattatca aattcatgcg caaaacctat
     5161 acgcgaatat agttgaggat aacgagatag ttttttctct atacccggca taccaataaa
     5221 tatcattgct aaattatgtt catcataaat agctcttaat tgctctaaat gttgcacttt
     5281 aaggcgatca atctcatcta ctataattaa atcaatatat ttaaacatat cactataatg
     5341 tttactatgt tcatgtccat acttatttac aacatgtaat ttttgaccca aatcaatgat
     5401 tgcagtaata ctatataaat cattccttaa tttagtttgt ttttctgctg gtgcattata
     5461 aaatatttta tccaccgata gtatgtcatc ggtcgtttta ctagctaaat cttcccaacc
     5521 tctatggtta acttgttttt caatagtatc ccaatttgtg taatacctag acgataaagt
     5581 ttttccgaca ccaggttgac cataacatat accaatatac tgatatttaa tacaagcatc
     5641 acaaaattca gcaaagcgtt tatactcttt cgtttcaatg aaattttgat ttttagtcat
     5701 tacgatatct ctttaatttt ttgacgtttt tagtcgtttc ttgaggtgaa taaccacaat
     5761 ttttttcttc cttaattaat tccgtggtac ttggactagc aatattttgt tttaagtgtt
     5821 ttcttctctg actacgagcg tgctgtatgt cttttatatc tatggagtaa tcagctattt
     5881 ctggacatat agcagtacaa agaaattcat ctctataaaa cacacgtatt tcagccatat
     5941 catttgggtt ataacgaatc agtacatatt cacctacata agcttctaga ttagtattac
     6001 tgtatcgaaa accttgaaaa tgaatgccat ctgaatgaac ttttctagat ttaggtattt
     6061 ccaacaataa taaatcaagt tgttctaagc tacttggcat attagggaaa aagtgattac
     6121 tattccaatg actgataggc gtggtatgaa tagtactatg ttctttttga ttataatctt
     6181 caattaaaaa gtaacgtaat ttttcttcaa aattgtgaaa atttattaga ttactaggag
     6241 tatcattatt gtttatatat ccaggcagtt gttctaagaa agtttgatta actgtctgaa
     6301 agaatcgttc tatttttcca cgaccacgag gaacaccaac tttcgaaaac atcaagttaa
     6361 ttttcaaatc aatagcgact tgttccatat gatgtgaagt aaagtcactt ccatgatctg
     6421 tgtagaattt ttcgggtata ccacacactg gccaattggt atcattttta ttccatattg
     6481 cttggtgtag tgttaatgct gtgttttgag cattgggggg catcaaaact taagaaatag
     6541 cctgcaattg cacgactata gtcatccata ataatagtta gccatggtct attgatatta
     6601 cctttttggt ctaatataaa gatatctagc aaagtatggt ctgcttgcca tatttcattg
     6661 ggtctcgagg attctctaat ttgtattaaa tcgtacttat tttgatagta tttttcaccc
     6721 tgatgagaga aatcaataac agacttaggc atcgctttaa taacactata aatttgttta
     6781 taacttggta tatcaaaatt attttcttta cagtaattag tgattttcct atgaattgtg
     6841 gctatactat ttcttttatt cataagcgca aggcgttcaa tttcatcaat tatctttggt
     6901 tctattttac gtgttccttt atcagctctt gtcgcataga ttagtccttt aagtccttgt
     6961 tctttatatg acttattcca cctataaagg gtgcttaacg caatcccttt acttttagaa
     7021 atacttgata aagattgttc gcctaggata aaaggtttta taatattgta cttttgagta
     7081 gcttttttac gtttggcttc agaaaaatta gttagatact tctccttgtt tttcatcttc
     7141 cttgtcctcc aatttattga ggtaacgata aattgttgta cgtgaaacat gccactgttc
     7201 tgcaattgtc ttaattggcg tgccattatc ataaagggtc ttaagtaagt ttaaatcttt
     7261 ttgatttaat ttttctggtc tgcctccata tcggcctcta gcacgtgctg caattcggcc
     7321 agctgaagaa cgctctaaaa ttaaattacg ttcaaattct gcaaatgctg cgaataaatg
     7381 aaataataat tgtccagttg aacttgattt atccattgtt atattttctt ctaaactatg
     7441 gaaacttaca cctcgttcgt taagctcatt aactaatgtg attaaatcct ccatattacg
     7501 tcccaatcta tctaatctcc aaacaacaat cgtatctcct gacctcgcaa attcaattgc
     7561 tttatctaaa ccaggtcttt tactttttga accactcata tggtcattaa atatcttttc
     7621 acaaccatat gtatttaatc gatcctcctg taaatttaaa ttttgtaatc cagttgaaac
     7681 tcttgcataa cctattttca aaatacaaac ctcctatata catcttcagt gtaccataac
     7741 ttaattacaa ggtcttttat gaacatagat tttttgttgg gtttttgaac acataatcct
     7801 atgtaattct tacttattta gacataaaag aagagtgtac agaaaatggt tattttctgt
     7861 acactctcat ctttaataat atattttaaa tgtcattaac aaaactaatt taataaaagt
     7921 caagcatagt ttacatatgt attatgtttg aaacatacct ctaattactt tttactaata
     7981 tcatttaaaa tatctcgcaa ttcttcaatt tctttgttat ttaattcttc atttttcgca
     8041 aaattcaaca ctaaactttt catatcccct ccatacagtt tattaagaaa ggttttagca
     8101 gttttcattt taatatcgtc ttctttaata tttgatgagt aaaaataaat attttctgat
     8161 ttgtatcgtt ttataatctc ttttttatat agtcttgtga ttaatgttct aatcgtttta
     8221 tcactaactt ctttatattt ttgaatttca actacaattt cattagctga tactgatttt
     8281 ttatcccata ttatattcat aacatcccat tcagccatag atatttcaac ttgcttattg
     8341 gccatttaaa acacccattc cttttaatat tttttcactt attaattcag catttttccc
     8401 agacgggttt ccatctgata aatgtgtagc aaaataatac ttatcatgat ttgtaattac
     8461 gtaacctaca aaccacccat tattatactt cccgtttact atacctgtac ctgttttccc
     8521 atacagttca tacttttcat ttttcttaat caataatgaa gaagataatt gattctttgc
     8581 ttttttacta aaatggttat tttgttccat catattttta aaaactatta cttgttcaag
     8641 attagatatt ttcaaactat cttccatcca atagctttta taacttccca aattttcatt
     8701 accataattt aattgcttga gttgagccgc agtatagttc tttggtattt gattactaat
     8761 acgttcgaag taccaattaa ctgaattttg cattgctgta tttaaatctt gttccttatt
     8821 ccaagactcg aaaagataat gtttatgatt ccatgacata cgtgaatttt tatcacttat
     8881 aatatgacgg tcaagtccaa acagtgctaa ataaattttg taagttgaat caggagaata
     8941 tctttttcta ctttcttttt cattataaat atagtatttg tctttcttca tgctgtacat
     9001 aacgaaagat ccactatttg aaccaaaatt tttactttca tctaaaattt ggtaatcgct
     9061 ttgtaagggc tttttataat tataatcagt taaggattgc cccattaaaa actggctttg
     9121 aattatcatg ataaaaaaag taaaaataca aataaaaatt agaattaatt ttgactgctt
     9181 tttcagatcg gcttctttta tattaattaa tctatttttg agtaatgatt ttttaccatt
     9241 aaatgaatgg cttaatatat ttttgttgaa aaatgaggtt tttaatacgg agtccataat
     9301 agattccgca taagttttaa attcattttt gttaatatta ttaaggacaa atctatcggc
     9361 ttctacttca ttgtcatgaa ttatctttct ttttacaata tgtactaatg gattgtaact
     9421 cataataata gagaagatat taaagataat taaatgtaaa gtatctctat ttttagcatg
     9481 agcatattca tgcagtatta tatattttag tcttttatca attacacttt taaaatatga
     9541 actaggaatc aaaataatat atttcccata ccaaaaagtt attggagatt gaatagcctc
     9601 tgcttttcga atcacaatat tttttttata ttgatggttg aaaagtatcg tatctatttt
     9661 atttttttca ttttcgttta gataaagtga ctgtttcttt aaatatttaa gatataataa
     9721 ggctttcaaa aatttaaaac ttaaaataat aactaaaact atccaaataa ctgtgcagat
     9781 attatcaatt gaatcccaat taaacttatg gatatctgtt gcgaactctt gaacaggttt
     9841 ggtggtaatt atgttatggt tcaagtcgtg tgacttactt tcaactgtgg gcgcttgatt
     9901 attcacatta ttaaatttta taaaagagaa tttaattggg ataaaaggaa ttaatccagc
     9961 aagcacagtt agataccaaa ctttataatt taaactataa ttaaaatagc gttttaatat
    10021 gtacctaaaa aatactaaca atagaaatat aaaacaaaag cttactacac tcattattag
    10081 taatttagcc attttgacac cttctttcaa atatttataa taaacaattg acatcaatat
    10141 tacaattgta atattattgt tttgtaaaaa ttacaactgt aatatcggag ggtttatttt
    10201 gaaaaagtta atatttttaa ttgtaatggc tttagtttta agtgcatgta attcaaacag
    10261 ttcacatgcc aaagagttaa atgatttaga aaaaaaatat aatgctcata ttggtgttta
    10321 tgctttagat actaaaagtg gtaaggaagt aaaatttaat tcagataaga gatttgccta
    10381 tgcttcgact tcaaaagcga taaatagtgc tattttgtta gaacaagtac cttataataa
    10441 gttaaataaa aaagtacata ttaacaaaga tgatatagtt gcttattctc ctattttaga
    10501 aaaatatgta ggaaaagaca tcactttaaa agaacttatt gaggcttcaa tgacatatag
    10561 tgataataca gcaaacaata aaattataaa agaaatcggt ggaatcaaaa aagttaaaca
    10621 acgtctaaaa gaactaggag ataaagtaac aaatccagtt agatatgaga tagaattaaa
    10681 ttactattcg ccaaagagca aaaaagatac ttcaacgcct gctgctttcg gcaagacttt
    10741 aaataaactt atcgcaaatg gaaaattaag caaaaaaaat aaaaatttct tacttgattt
    10801 aatgtttaat aataaaaacg gagacacttt aattaaagat ggtgttccaa aagactataa
    10861 ggttgctgat aaaagtggtc aagcaataac atatgcttct agaaatgatg ttgcttttgt
    10921 ttatcctaag ggccaatctg aacctattgt tttagtcatt tttacgaata aagacaataa
    10981 aagtgataag ccaaatgata agttgataag tgaaaccgcc aagagtgtaa tgaaggaatt
    11041 ttaatattct aaatgcataa taaatactga taacatctta tagtttgtat tatattttct
    11101 attatcgttg acatgtataa ttttgatatc aaaacctgat tttcccttta ttattttcga
    11161 gatttatttt cttaattctc tttaacaaac tagaaatatt gtatatacaa aaaatcataa
    11221 ataatagatg aatagtttaa ttataggtgt tcatcaatcg aaaaagcaac gtatcttatt
    11281 taaagtgcgt tgcttttttc tcatttataa ggttaaataa ttctcatata tcaagcaaag
    11341 tgacataatt gttgaattta tagtaactga aacgtatgat tagggtgtat attaattatg
    11401 agatggaaat caatgattgt tggctatgcg agagtatcat cgaacgatca aaatttagaa
    11461 agacaacttg aaaatttaaa gacgttttgt gctgaaaaaa tatttacaga aaaacagtct
    11521 gggaaatcta ttgaaaatag accagtactt caagaagcac ttaacttttt gaggatggga
    11581 gatcggtttg tagtagaatc cattgattgt ttaggtcgta attatgatga agtgattcat
    11641 accgttaatt atttaaaaga caaagaagta caattaatga ttactagctt acctatgatg
    11701 aatgaagtgg ttggcaatcc attactggat aagtttatga aagatttaat tattcaaata
    11761 ttagcaatgg tttcagaaca agagagaaat gaaagtaaac gtcgacaagc gcaaggaatt
    11821 caagttgcga aggaaaaagg cgtatataaa gggcgcccct tactttattc accaaatgct
    11881 aaagatccac agaaacgtat tatttatcat cgcgttgtag aaatgttaga agaaggccaa
    11941 tcaattagta aaattgcgaa agaagtaaat ataacaaggc agacgattta cagaattaaa
    12001 aacgataatg atttgattta ataaactttg tttcaatgca actgagagct tctcacagcg
    12061 tctcaaaaca gatgattata atctattatg agtttttaat aataagacaa gaaaagagag
    12121 cgtaaatatg ctctctcttt ttctcattaa cgaatgttta taacgcaatc atgatgagag
    12181 tattaataca gttaattatt tgaaatactt tagtttatat aatgttgaat tataggtagt
    12241 gaaattgtat ttattataca ttgtcatatc gttgtttaat gatagttaat ttaaggataa
    12301 tagaattaat attatatata gatgaacaaa acaagcaaca gagcagaaaa aacactttta
    12361 gattattttt actcattctc tattttattt atttttgcta taataaataa agaatattaa
    12421 atggaggtgt ttttatgaaa aagaaatttg tttctagttg tattgctagt acaatcttat
    12481 tcggcacttt attaggtgta acttataaag ctgaagctgc aacagtacat gtagctggtg
    12541 gtgtttggag ccatggtatt ggaaaacatt acgtatggtc ttattatagt cacaataaaa
    12601 gaaatcatgg ttcaacagca gtagggaaat attcatcttt tagtggtgtt gctcgacctg
    12661 gtgttcaatc taaggcatct gctccaaagg cttggggtgg aaacaaaaca ttttatagtc
    12721 ttcactaatt acatatatta attaaggaga atagacagaa ttaagtaaac ttaattctgt
    12781 ctattctctt gaaagaggca atatgaaaaa attcaaatta tttttagatt ttagtacttt
    12841 attattaatt tcagggctat tatttttatt tttcttcaaa gaaaatgaag aaattatacc
    12901 tgaaagttcc aatattttaa caatctctaa ttgggataaa tctaacagta aatcaaaagt
    12961 gttagatgtc attgaatcag gcgccaaaaa tcaaaatata caaataatta aatccgttaa
    13021 agattttgat aataaaaaag aattttttgt tttcaactca aaacgaaata attctgactt
    13081 tatacgtaat aaaacatcac ttttaactcc atcagattta ttaaacagag agataaaagg
    13141 aaagtattat attattggtg aacatttcaa tgtagaagag cttacgagtg aattaaaaaa
    13201 agctggttta acatctgaag ttgaatacat aaatagaaac atattatttt ttgaattagt
    13261 catagataat gatttattag tgcctttcat attcttaggc gtattatatc ttttgtactt
    13321 cttatatgac agaggatata atttgaaatt ttatgctatt caaaagctac atggcttttc
    13381 aactacacgc attatttttc ataatattca tataaaaatc atttattggc tagtacttac
    13441 cgctattttc tttattgcta atatattaat cattcatata gccaatttag aattggattt
    13501 cttaatgttt attcgtagat ttatcgtgtt gctttttgtt tttgcttgta ttactacatt
    13561 gctgtggctg atttcgtata gtcttctttt gaagttaagt attccattaa tcttaaaagg
    13621 gaaaaaagga tataagtttt caatatttat gggtaccttc accaaatgta tcatggtgct
    13681 aatactatct tttttactgg cacaaaattt aaatgcttat acgaagttaa agaatatata
    13741 tgactctgaa aaaatctggc aaaagttaga taattactat acattagaga tttctcctaa
    13801 tattagaaat tcagaagaaa aacaaatttt agaaactaat atatacaatt taattaagaa
    13861 aagcgaacaa cttggtggat tgcttttaaa gaataataat atagccaatc ccgataaaaa
    13921 caattacatt cctgaaaatg gcaatgtctt ttttatcaat aacaattttc tgaatttcta
    13981 taaaaatata aatcatgatt ttaaaatgat tgacaatcat tcggataaaa taaacgtgtt
    14041 tattcctcca aggttacaat atcaaaaatc tgaaattcaa aaaaatcacc aaggatggat
    14101 tgactttcaa aagcaacaaa acaaaaaagt agatgtgcaa gtactgtcaa aaaacgtatc
    14161 tgttttttct tttgatcgca caactaattt gaaatttggg tatctagatt ctccaatagt
    14221 aatgttgttg acacttgacg atttaacagg agatttttat ttagctgctg tttctcaagg
    14281 tggatatcta tttaaagatt tagatacact taaacagttg cttaaagata atcacctaga
    14341 agaagaaatt agcggtataa ctaattacaa ggattctgtg ttaaatgaat taaatgaaac
    14401 gaaaacaaaa atgataataa caatagttac tattattatt aacgttttca ttcttttgat
    14461 agctactgta tttgaaacaa ttcaatattt tagctggaat aaaaagcaac tattattaag
    14521 aaaaattcat ggttattcat tattcagcag taatgtacgt tatttaacaa tttctatctt
    14581 actttctatt atgttagctt acactacgca tattttattt ggttcaaaga tattactatt
    14641 cataataatg tctattgcta ttattcaaca tttacttcaa attgcttata ttaaatatct
    14701 tgaaaaatac tttaaagatt taatgaggga gatttaaaca atgaaaagaa ctttaattat
    14761 tgtaacaatt gtactattaa tcatcatact tagtctgtta ttggttagaa atgagcattt
    14821 agatcgtttt aacccactgt taaaagaaaa agtatcttat gccaaagttc caaaagatac
    14881 ccaggactat agaaatataa ctgtatactc taaaaatgga gaaaaaaaga gttataaatt
    14941 ggatttttta ggttatgatc ctacaaaaga atatgtgaaa gtaaatcata aagggaaata
    15001 tgtgcgttcg atagaataca ttacaaaaga tattcctagc tttttaaaat gaggtgaccg
    15061 atagtgataa aacttgaaaa tgtttttgta aaaaaaggta ataaaaacat tttagacgga
    15121 tgtaacttta attttgaaaa aggaaaatca tatgctttag ttggagaaag tggcgctgga
    15181 aaatctactt tacttaacat aatcgctggg ttcgaagatg tatcacaagg aagcatatat
    15241 attgaagata agttactaaa aaagaaagtc gatttttata gatatacgtt agggtatttg
    15301 tttcaaaatt ttgctttact tgaaaatcaa acaatcagtc aaaatttaga tttagcccta
    15361 aagttcaaaa agaataaaaa agataatatg aacttaaaga aagaagtatt aaaaaaggtc
    15421 ggcctagatt tagatatcaa gagaattgtt agttctctaa gcggtggtga acaacaaaga
    15481 gtagcattgg caagattaat attaaaagat ccgaaaatca ttttagctga tgaacctact
    15541 gggtcactag atacgaaaaa tggaaaaata gttattgatt tattattgaa gctacttgat
    15601 gaaaataaaa ctatgattgt cgtaacgcat gatttagagc ttgcgaaacg atttgatgtc
    15661 atagtcaata tttctgagct tagaagttaa gaaatattga taggtatagc catacataga
    15721 gaaaaaacaa tatgaaatat gattagtcat tacttttgag ttttttaatt taaggactgg
    15781 attttccagt ccttttttat gatgacaaaa aacaagcctc gcagagcaca cgtttttaat
    15841 gacttatttg gtttttaata agtctagtat gttaaaactt ttctgtgttt aggtgttata
    15901 atcatatgca gtggaagttg atttattatg tcttattcaa ttattcgagt tgttaaagtg
    15961 aaatcaaaaa caaatacaag aggtattcaa agacatattc aaagagaaaa taaaaattat
    16021 gaaaatatag atattgattt aagtaagtca tatttaaact atgatttagt caatgatact
    16081 aagtttgatt ttaataaaaa aattgatgag aaaatcgaaa aaaattataa agggaaacgc
    16141 aaaattagaa cagatgccat taaacatatt gatggattaa ttacatcaga taatgtgttt
    16201 tttaatcaat tatctgaaga agagacaaaa tagtttttta agcatgctaa agcgttcttg
    16261 gaagaagaat acggtaaaga aaatctttta tatgcgacag tacatatgga tgagataaca
    16321 ccacatatgc attatggcgt agttcctatt actaaagatg gacgtttaag tgcgaaagaa
    16381 gttgtaggta ataaaaaagc attaaccgaa ttccaagata gattcaatac gtatattaat
    16441 aagcaaggct atgatttaaa acgaggaatt tctagacaac ttacaaaaga aaaacatgat
    16501 caagttagcc gttataaaca aaaaacagaa tatcataaac aaatgcatat gcgctagaag
    16561 caaatagagg attatttaaa gcaagaaaat gataaattga tacaaaacta ccaaaaatca
    16621 ttagatacgc ttaaaaagct tctgagtgtc atgtatgaaa ttaaaactaa aaatgtaggt
    16681 ggatggtttc ataaagagaa gcaagaaaca ggcaatattg taattactaa aactgatttt
    16741 gaaaaataca ctaaacaaat taaagcagca cagatgatat tagatgatta tgaatgtatt
    16801 aaaagtggga agtcattaaa aaaagcagag aaacaaaatg aaagtttagt taatgaattg
    16861 actagtgtcc atatggaaaa tgaaaagctg gttgaagaat ttaatgattt agcacaacgt
    16921 tataattatt tgttgtcaga gaatgaaaag aaagataaag aactaaatta tacgcttaag
    16981 ttattcaatc aagtttttaa aatcattaaa agtatgatga aagaagagcg ttatcataca
    17041 ctaataaatc atattgataa tcatttagac aattctaaaa tacgtgaagt aatgacgata
    17101 gataacaatg atgaacagtt ctttaagaag aaatatcaag cacaagaacg agaaatcatt
    17161 tttaaagaag atagagaaga tggttataca ttataaaaat agatatttaa atgcatttgt
    17221 ttgaggttaa ttatttttta ggatgaaaaa taggtagccc ccctcgaact ttttaatata
    17281 tttttataaa tctttttaaa aaccttttta ggggcttgtt cagccctaga gcaacaaggg
    17341 atttcaatgc ctaaaggagt gtttttgcca cataaaagga gtgtttttgc cacataaaag
    17401 gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt tttaaaaagt
    17461 tgtactcctt ttatggtttg acattgataa taaagtagtt tattgtgaat aaaagttttc
    17521 aaatgggagt gtatattcaa acgatactcc tttaggttcg taataaaggg ggctgtatca
    17581 tgacaggaga gacagttgta tataaaaatg aaatgaattt agttccatta aggcgattta
    17641 cagctactga aattaattta ttttttgcga tgtgtaataa attaaaagag caagatacta
    17701 atacattacg tttgtctttt gatgaattaa aaaaattaag taattatagt ccagaaacac
    17761 gtaatattaa tagatttgct aatgatttag ataatgtgta taaaaagatg ttgaatttaa
    17821 ccattagata tgaagatgat gatgtaatag aaagattcgt tttattcaat cattatagaa
    17881 tccataagcg agaacaatat ctagaaatat caacttcttc aaatttaaaa cacatattga
    17941 attcaattac taataatttt acaaaatttg aattaaaaga aatgactagg cttaaatcta
    18001 catattctaa aaatatgttt agattactta aacaatacaa acatacaggc tatttaaaaa
    18061 ttcacatcga tgattttaaa aatcgtttag atatacctaa atcttatcgt atgactgata
    18121 ttaacaaaaa tgtttttaaa cctattatta ttgaattagg ttctatattt aataatctta
    18181 ctatcaataa aatcaaagcg aaaaaagggc gtaaaattga atggatagag ttcacatttg
    18241 acgctgagaa acgcattcat aacaaacgac aacctcaaat gtccaagata gataaatcaa
    18301 gacaatatgt gaggcgtgaa aagacgccta aatggttaga agaacggtca tatgaaaagc
    18361 aacctcaaaa agattacgac ccacaattag agaaagaacg agaggatttt ttaaaacaac
    18421 ttgaactgaa ttgggaataa cgcaactttt cgttgcgagt tggttaacta aaagtatcgt
    18481 gacttttcaa ttattttaat tatagtttga gttaaggagt gattttatga aattagctga
    18541 agctataaaa gaacagagag aattaaaagg atggtctcaa gaggaattag ccaatatatt
    18601 aaaggtttcc agacaaagtg tttctaaatg ggaaagtgcc aaaaactatc cttccttaga
    18661 tattttgatt gctatgagcg atttattcgg aatctcttta gagcatttaa ttaaaggaga
    18721 tgcacgtttt aaaaaagtta ttttagaggg aaattataga gagagtaaca gggtaccttc
    18781 catagttgat tttctttatg atttttggtg gcttttcttt cctgttgccg gatttttagt
    18841 ttgggccatt cattcgttca tgggttgatt ttaaaatcaa aatttaatgc acatcaggca
    18901 atatgaaaaa ggaaagtatt tttacgacac cttgaaatgt attgataaga atagaagagt
    18961 ttacaaaagg caatatgaaa tatatactaa aagtaacaag aatttcgttt gtaaacgcac
    19021 aaaaccccga actattcgcc gtagttcggg gttttttggt gaattggctt taatcgtcta
    19081 tattattttt tatcacgttt atggagctaa taaccaaata acgtaacgag acaaccactg
    19141 attgccgttg tcatgatgtg aacaagaatt tcattcataa atcgcacctc ctctctacgc
    19201 cgaattgaca tctgagagat agacgacctt cacattataa caaatctctc cttccatgaa
    19261 ataacatgaa tattaataaa tgttgttata tattaaagat aaataaatat aagggtggga
    19321 ttgataatgt ttggcgatca aagacaagaa gctacaaaat atgtcattaa agaaggttat
    19381 caagatattt atttcctcaa caaaaacggg gaatggtatt atttcgaagt aagaagtgtc
    19441 tggcgtggca aacatattat tagagttaaa gatggtttgt taggttggag aaaagaaata
    19501 gtaactgaat aaagatacaa aatacttgcc aatgcaaaag aatgaaaacg cgtcaaatca
    19561 acgatgtata aaagatgcat aaaagataat gaaagtaaaa agccataaat gccgtcatat
    19621 aggcatttat ggctttttgt ttggttaaca taatcgatga ttatcagaag ttcaattcac
    19681 ataaaaaagc acggctaatt tatgaacttg tcgtaccttt ttaattaaaa ttagttacca
    19741 aatagacgac tccaaaaccc ctttttaggt tccgtttctt cactcttttc ttctatatca
    19801 ctatcattgt catttggatt agctgaaacg tcttctcttt gtgcttcttc accttgtgta
    19861 ctttcgtcgc tttgacttcc agatatatcc ttatattgaa tctctgtttc tttagtttct
    19921 tcctgatctc ggttaatatt tacaggacta gtagtatatg ttttttcttg tgcatcaacg
    19981 ttttgtctag cgttagtaga tgtatcaaag ggataattaa ggtgtttttc tttttctaat
    20041 tgattttcta atttttgaat ctttttatta ctctctaatg ccagaacttg ctgattctca
    20101 agcaattttg atctttcttg caactctttt ctgtaaaatt caattgttgt ttcatgacga
    20161 ctttcttgtt tttcaatttg attatttaaa gtattaatct gatttttaag tatttctact
    20221 atttgagcat cgcttttaga ttcaaaatta atattatccg actctttttt ttgtttgtct
    20281 tcagtagcac tttcaaaacc atatttcttt ttattttcat ttactctttg aatgattttt
    20341 tctatatcgg tatcttcttt aataaacgaa gtgttttcct gttttattgt ctctatattc
    20401 aatctcttaa tattattaaa aatcgtttgc ttactaaccc ctaattcttc actcaacctt
    20461 tttacacttt tcatatcatc aaccctttat aaaatgttta taaaccctta gtaaaatatt
    20521 ataagcttat aacgattaat aataaagtaa tcgacaaata aaaatataaa ttcgccaacc
    20581 tttttatcaa gggtttgtaa agggtttatg gtgtttatca aaggtttata aacctatatt
    20641 ttcccttttt taagtttatt caaagtgcta taataacctt aatataacaa aaaccccaac
    20701 tactggtaat agtcggggt
//
