LOCUS       CP110761               11645 bp    DNA     linear   BCT 14-NOV-2022
DEFINITION  Klebsiella pneumoniae strain INF102 plasmid pINF102.2, complete
            sequence.
ACCESSION   CP110761
VERSION     CP110761.1
DBLINK      BioProject: PRJNA646837
            BioSample: SAMEA3356970
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 11645)
  AUTHORS   Foster-Nyarko,E., Cottingham,H., Wick,R., Judd,L.M., Lam,M.C.,
            Wyres,K.L., Tsang,K., David,S., Aanensen,D.M., Brisse,S. and
            Holt,K.E.
  TITLE     Nanopore-only assemblies for genomic surveillance of the global
            priority drug-resistant pathogen, Klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11645)
  AUTHORS   Foster-Nyarko,E., Cottingham,H., Judd,L.M., Hawkey,J., Wick,R. and
            Holt,K.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2022) Department of Infectious Diseases, Monash
            University, Level 2, The Burnet Institute, Melbourne, VIC 3004,
            Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 14x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 11/08/2022 12:26:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,586
            CDSs (total)                      :: 5,462
            Genes (coding)                    :: 5,209
            CDSs (with protein)               :: 5,209
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 253
            CDSs (without protein)            :: 253
            Pseudo Genes (ambiguous residues) :: 0 of 253
            Pseudo Genes (frameshifted)       :: 107 of 253
            Pseudo Genes (incomplete)         :: 139 of 253
            Pseudo Genes (internal stop)      :: 31 of 253
            Pseudo Genes (multiple problems)  :: 20 of 253
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..11645
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="INF102"
                     /db_xref="taxon:573"
                     /plasmid="pINF102.2"
     gene            1..183
                     /locus_tag="JMX38_02205"
                     /pseudo=""
     CDS             1..183
                     /locus_tag="JMX38_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004893531.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /name="enterobactin synthase subunit EntD"
     gene            301..1242
                     /locus_tag="JMX38_02210"
     CDS             301..1242
                     /locus_tag="JMX38_02210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose ABC transporter substrate-binding
                     protein"
                     /protein_id="UZL65987.1"
                     /translation="MKTTLIKSVLFASMMAASGSLFAADNGLIAIITPSHDNPFFKAEA
                     DGAEAKAKELGYSTLVASHDDDVNKQNQLIETAIARKAKAIILDNAGADATVGPLEKAK
                     AAGVPAFLIDREINKTGVAVAQIVSNNYQGAQLGAEKFASLLNGKGKYVELLGRQSDTN
                     ASVRSQGYHDVLDDYPEMKMVAQQTANWSQTEAFTRMEAILQTNPDIVGVISGNDTMAL
                     GAEAALKAAGKNDVIVVGFDGSDYTRDSILKQGNIKATVLQPGWKQAQMAVEQADFFLK
                     NGKAQKEEKQLMDCILIDSGNAKKLNMFNLSE"
                     /name="D-ribose ABC transporter substrate-binding protein"
     gene            1253..1861
                     /locus_tag="JMX38_02215"
     CDS             1253..1861
                     /locus_tag="JMX38_02215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2291 family protein"
                     /protein_id="UZL65996.1"
                     /translation="MRLKQWGAVLMGCAALLLTACTVVDLDENGKPVLPADPNAKPSFD
                     HLTPQQIAQQTWQSRVIDAANQHALDATALEKVRQASGATPQSVFVRLNSEVTGTDVSN
                     PREQKLTLTLLGQPLVVQLGPVMRGNAIRDASGLKFEDFTNQVQFAQLSRAYNREAIKS
                     LPTVDASWTGKPVDILFAVTVVNGSLQDAAALELKQEAR"
                     /name="DUF2291 family protein"
     gene            1861..3387
                     /locus_tag="JMX38_02220"
     CDS             1861..3387
                     /locus_tag="JMX38_02220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016160460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="UZL65988.1"
                     /translation="MASSPAEEIILRTRGISMLFPGTVALDNVDYNVWRGKVNVIIGEN
                     GAGKSTLMKILAGVQQPSLGEMELNGNIVHFSSTREAAAHGIGMVHQELNLFENLSVAE
                     NIFLGRELQRGLTPINEAEQERQAAELLQRLDQPISPRELVGNLKVGQQQLVEIAKALA
                     ENADILILDEPTSALSKTEVDILFRVIRELTRQGVSIIYISHRLEELMAIGDVITILRD
                     GKFQAEARVSEIDVPWIVREMLGSDPVSHFLPPNRRFGAPLLEVENLTCVNAAGNTVVD
                     NVSFKAHAGEIIGIYGLMGAGRTELFECLLGTARHYFGKIWLDSKPVPQRLTTAERIRM
                     GMSLVPEDRKRTGIFPISSVASNLTIASLWRRLQRGVTIANKEEEAVVASTIGNLSIKV
                     SSPEVEIQALSGGNQQKVVIGRSLLTNPKVLFLDEPTRGIDIGAKGDVFRMMVQLSQQG
                     MAVVFSTSDLKEIMAVSDRILVMSGGKLTADIVRDQAEESALVSASAQGF"
                     /name="sugar ABC transporter ATP-binding protein"
     gene            3389..4477
                     /locus_tag="JMX38_02225"
     CDS             3389..4477
                     /locus_tag="JMX38_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="UZL65989.1"
                     /translation="MKMTQSVALAPRGGASLSRENILLLLLKLRTFIALFLIVGFFTMT
                     VPGFLSAGSMVIMIKHIAINAFLALGITFVIITAGIDLSIGATLGLCGMIAGWLITKGI
                     VLPMFGIAIFPSVWVIVPLVLLIGALIGAVNGWIITRYNVAPFICTLGTMYVLRGAAML
                     TSDGQTFPGLAGNPQLGNTGFDEIGAGALFGIPWAIWLMILLALIIAYIARRLPFGRHV
                     YAIGDNERAAELSGVKVKQIKVLVYTLSGFCAAIAGIVVSAQLLASHPANGTAFEMNAI
                     AAVVLGGTSLAGGRGTILGTLIGAFVIGFLADGLVMMGVSEFWQMVIKGIVIIVAVIID
                     QMQNRMQQKAAVVAQKAVMENK"
                     /name="ABC transporter permease"
     gene            4633..5604
                     /locus_tag="JMX38_02230"
     CDS             4633..5604
                     /locus_tag="JMX38_02230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="UZL65990.1"
                     /translation="MKKRPHSTPHDSLFKRFLRDNETARDFLDIHLPPALRQLCDLSTL
                     HLESGSFVEDNLRASYSDILYSLQTSKGEGYIYVVIEHQSTPDSHMAFRLLRYALAAMQ
                     QHLDRGHKALPLVIPMLFYHGSISPYPFSLCWLDEFPPDSPAKQLYLGAFPLVDVTDIP
                     DDAILQHRRIALLELVQKHIRQRDLSYILQQLVEVVLMGYTDHQQFKTLFTYMSLHGNS
                     ADPENFIDQLVERLPQYEDTLMTIAEYLKQKGREEGKQRWLQEGLNEGLQAGEHREACR
                     IALMMLENGMDTETVLRMTRLSADELATLARQARQSSPPLNP"
                     /name="Rpn family recombination-promoting nuclease/putative
                     transposase"
     gene            complement(5594..6544)
                     /locus_tag="JMX38_02235"
     CDS             complement(5594..6544)
                     /locus_tag="JMX38_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="UZL65991.1"
                     /translation="MSKQDEQRLLVKIATLYYSENKKQSEIASLLHLSQSFVSRALTRC
                     QKEGLVKITVVQPTNIFVDLEKAIEERFGIRQAIVVDVGENASYSQVKHAIGSAAAHYV
                     ETRLRPEDLVGISSWSSTIRCMVDEMHPQNIRAAGVIQLLGGVGPNGNVQATILTQQLA
                     AHLGCPAWLLPSQSIEHSVEERSRLVNSPDVAAVVAKFAEVDVAIVGIGELEPSQLLKN
                     SGNYYNETMLQLLAARGAVGDICLHYYNAAGKPVLSQDEDPVIGMELDQIRRCPQVIAL
                     AGGVDKENAIRGALQGDYIDVLITDFPTARALIKG"
                     /name="sugar-binding transcriptional regulator"
     gene            6856..7686
                     /locus_tag="JMX38_02240"
     CDS             6856..7686
                     /locus_tag="JMX38_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="UZL65992.1"
                     /translation="MNPFSLSVKELEQKARAIRRRIIVLNAESPAGGHTGADLSQVELL
                     TALYFRILNCSPARKESDDRDIYIQSKGHAVGGYYCVLAEAGFIPVDWLATYQHADSAL
                     PGHPVKHKTPGIELNTGALGHGLPVAVGIALAAKRDNNPRRVFVVTGDGELAEGSNWEA
                     ALVAAHYQLDNLIIINDKNNLQLAGATKEIMNTDPLDEKWRAFGMEVTQCNGNDMAEVV
                     ATLEGLQPNGKPHVVIANTTKGAGISFIQGRPEWHHRVPKGEEIELALEELKDE"
                     /name="transketolase"
     gene            7679..8629
                     /locus_tag="JMX38_02245"
     CDS             7679..8629
                     /locus_tag="JMX38_02245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="UZL65993.1"
                     /translation="MSNSEHLATVMVNAFIDAVDRGVDLVPVVADSTSTAKIAPFIKRF
                     PGRLVNVGIAEQTLVGAAAGLALGGKVAVTCNAAPFLISRANEQIKVDVCYNNTNVKLF
                     GLNAGASYGPLASTHHSIDDIAILRGFGNIEIYAPSSPGECRQIIDYALAHVGPVYIRL
                     DGKALPELHDERYRFVPGNIDVLRLGRDIALVAMGSTVHEIVEAAAQLAAEGIDATVIS
                     VPSIRPCDTQALLAAIQSCPAAITVEEHNVNGGVGSLVAEVLAEAGCAIPLRRLGIPDG
                     QYAIAADRAATRARHEIDAAGVVKHARKLLTKKAC"
                     /name="transketolase family protein"
     gene            8664..10082
                     /locus_tag="JMX38_02250"
     CDS             8664..10082
                     /locus_tag="JMX38_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose/L-arabinose isomerase family protein"
                     /protein_id="UZL65994.1"
                     /translation="MSRIPQQLTMGVIIGNRGFFPSYLVAEAREQAVALFSRLGINTIM
                     LDPSQTELGGVETRQDAKICAELFRTHRDKIHGVVVLLPNFGDEKAIAETLRLSGLNVP
                     VLIQAEEDNLDKMGLSTRRDSFCGKISLCNNLRQYGIPFTLTTQHVCALSGEVFEQDLR
                     RFTQICRVVNSMRGVRVGAIGARPAGFNTVRYSEKLLERLGIAVETLDLSEVFTRIKAL
                     RDDDIRVDEKRRLLIDNADASGIPADKLITMAKLFVVLSEWIVANDIDTTAIQCWTSLQ
                     ENLGINVCSIMSVMSGQLMPSACEVDVMGALSMYALASSNLSPASIADWNNNFGDDRDK
                     CVLFHCGNFASASLESPHMGTADIIGTTVGKENTCGAVHGRMKSGALTYFRLSTDDLTG
                     EIKAYVGEGQSVDDPLDTVGCRAVIQVPHLENLLSWICRNGFEHHVAMNHSASAAILHE
                     AFTRYLGVSTYLHQ"
                     /name="L-fucose/L-arabinose isomerase family protein"
     gene            10097..11596
                     /locus_tag="JMX38_02255"
     CDS             10097..11596
                     /locus_tag="JMX38_02255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="UZL65995.1"
                     /translation="MSVNKDIIIALDEGTTNAKAVAFDSHGRVIAQFSRALEIATPQEG
                     WVEQSAELLLAASLEAISRTVAAVGAERVAALAISNQRETVVGWYRETGEAIAPALSWQ
                     CSRTAAFCHMLREQGHEPQIKAVTGLPVAPLFSASKMRWLLDHTPDGLNRAKDGEICLG
                     TVDSWLLWHLTQGQHFCCDYANASRTQLMNLQTADWDTDMLALFGIPCAALPVIKPSSG
                     LFGYTAGLATLPDGIPVMAMIGDSHAALFAHGLGATGCVKATYGTGTSVMAPVDSVAFH
                     VSNLATTVAWHDGEKLVYALEGNIPHTGDAVAWMADSTGLSERSPAELAQALNALPRSV
                     DSTLGVFFVPALTGMGAPWWDDKARGLIHGLSRGVKRAHLIRAALESITYQIADVITAM
                     RAHHGFTLNTLLVDGGPTKNDWLMQYQADLLGCPVMRSDVAELSATGAALLARKALHKL
                     TVAELQPFLPEHITYAPDLLRHHRLVQRWQSWQHAVKLARR"
                     /name="FGGY-family carbohydrate kinase"
ORIGIN
        1 tcacacgctt tagccctgcc cggcttccac agcgcccgaa ttgtggcgct cactgcgcag
       61 caggttcatt tacgttttac cgccagcttc tccgtacagc ttgctgattt caccttgcaa
      121 atcaatcatc tgataaaaga cgatttcgtt attacctgta cctgcccgcc tcgcgaagcg
      181 tgatcctttt cgctttttaa gaaattacct gtgcaaaccg tagacagttc tggctggccg
      241 ctttatggtt acattgaata ataaatcatt attgaatata tattcaatgc ggagataata
      301 atgaaaacta ccctgataaa gtctgttctg tttgcctcca tgatggccgc atctggctca
      361 cttttcgccg ccgataatgg cctgatcgca atcattaccc cttcacatga taatcctttc
      421 tttaaagccg aggctgacgg cgcagaggcg aaagcaaaag aactgggtta cagcaccctg
      481 gtcgcctctc acgacgacga cgtcaacaaa caaaaccaac tgattgaaac ggctattgcg
      541 cggaaagcca aagccatcat ccttgataat gctggcgcgg atgctaccgt cggcccgctg
      601 gaaaaagcaa aagcggcagg tgtgccggca tttttaatcg acagggagat caataaaacc
      661 ggcgtcgccg tggcgcagat cgtctctaac aactatcagg gcgcccagct tggcgcagaa
      721 aagtttgcca gtctcctcaa cggtaaaggc aagtatgtcg aactattagg tcgtcagtca
      781 gacactaacg ccagcgtccg ctcgcagggt tatcacgatg tgctggacga ctatccggaa
      841 atgaaaatgg tcgcccagca gacggcgaac tggagccaga cggaggcctt tacccgtatg
      901 gaagccattc tgcagacgaa tccggatatc gtcggcgtga tttccggcaa cgataccatg
      961 gcgctggggg cggaagcggc gctgaaagcc gcgggtaaaa acgacgtgat tgttgtcggc
     1021 ttcgacggca gcgactacac gcgcgactcg atactcaagc agggcaacat taaggccacg
     1081 gttctccagc ccggctggaa gcaggcgcaa atggccgtgg aacaggcgga ctttttcctg
     1141 aagaacggga aagcccagaa agaagagaag cagttgatgg actgcatcct catcgatagt
     1201 ggcaatgcga aaaaactcaa catgttcaac ctcagcgagt aaggcggaaa tgatgcggtt
     1261 aaaacaatgg ggcgccgtgc tgatgggctg cgccgccctg ttgctgacgg cctgcacggt
     1321 ggtggactta gatgagaatg gcaagccagt gctgcctgcc gacccgaacg cgaaacccag
     1381 cttcgaccat ctcaccccgc agcagatcgc gcaacaaacc tggcaatctc gagtgattga
     1441 cgcagcgaac caacatgcgc tggacgcgac tgcgctggaa aaagtgcgtc aggcctctgg
     1501 cgcgacgcca cagagcgtct ttgtccgcct gaacagcgag gtgaccggga ctgacgtcag
     1561 caacccacgc gagcaaaagc tcactcttac gctactgggc cagccgttgg tcgtgcagtt
     1621 gggtcctgtc atgagaggca acgccattcg cgatgccagc ggtttaaaat ttgaagactt
     1681 taccaaccag gtgcagtttg cgcagctttc acgcgcctac aaccgggagg caataaaatc
     1741 gttgccgaca gtggacgcga gctggacagg caagcctgtc gatattctct ttgcggtcac
     1801 ggtggttaac ggcagcctgc aggatgcggc cgctcttgag ctaaaacagg aggcgcgctg
     1861 atggccagtt cacccgcaga ggaaatcatt ttacgcaccc gtggtatttc catgctgttc
     1921 cccggcacgg tggccctgga taacgtcgac tacaacgtct ggcgtggcaa agttaacgtg
     1981 atcatcggcg aaaatggcgc gggtaaatca acgctcatga aaattctcgc cggtgtgcaa
     2041 cagccgagcc tgggcgaaat ggaactcaac ggcaacatag tccatttctc cagcacccgc
     2101 gaggccgccg cccacggcat tggtatggtc caccaggagc tgaacctgtt tgaaaatctt
     2161 agcgtcgcgg aaaatatctt tcttggtcgc gagctacagc gcgggcttac gccaattaac
     2221 gaagcagagc aggaacgaca agccgcggag ctgttgcagc gactcgatca gccgatctcg
     2281 ccgcgggagc tggtgggtaa cctgaaggtc ggtcagcagc agttggttga gatagccaaa
     2341 gcgctggcgg aaaatgcgga cattctgatc cttgatgagc ctacatccgc cttaagcaaa
     2401 accgaggtgg atatcctgtt tcgggtcatc cgcgagctga cgcgtcaggg ggtgtccatc
     2461 atctacatct cacaccgtct ggaagagctg atggccatcg gcgacgtcat taccattctg
     2521 cgtgacggca aattccaggc ggaggccagg gtgagtgaaa ttgatgtgcc atggatcgtc
     2581 cgtgaaatgc tgggaagcga tccggtaagt cattttcttc ccccgaatcg ccgcttcggt
     2641 gccccactgt tggaagtgga gaacctgacc tgcgtgaatg ccgcgggcaa tacggtggtg
     2701 gataacgtca gttttaaagc acatgccggt gaaattattg ggatctacgg tctaatgggc
     2761 gccggacgaa ccgagctgtt tgaatgtctg ctggggacag cgcgccacta ctttggcaag
     2821 atctggctgg acagcaaacc ggttccccag aggttaacca cggccgaacg catccgcatg
     2881 ggcatgagtc tggtgccgga agatcgtaag cggaccggga tttttccgat ctcttcagtc
     2941 gccagcaatc tgaccattgc cagcctgtgg cgtcgtcttc agcgcggggt aaccattgcc
     3001 aataaagagg aagaggccgt cgtcgccagc acaattggca atctatccat caaggtctca
     3061 tcaccagaag tcgagatcca ggcgctcagc ggcggcaatc agcaaaaggt ggttattggc
     3121 cgttcgctgt taaccaatcc gaaggtgctg tttcttgacg agcctacgcg cggaatcgac
     3181 atcggcgcca agggggatgt gtttcgcatg atggtgcaat tgtcgcagca gggaatggcg
     3241 gtggtgttct ccacctccga tttaaaagaa atcatggcgg tctctgaccg tatcctggtg
     3301 atgtcaggcg gcaaactgac cgccgatatc gttcgtgacc aggccgaaga gtcggcgctg
     3361 gtttcagcaa gcgctcaggg gttctaagat gaaaatgaca caatcggtcg cactggcgcc
     3421 gcgcggcgga gcctctctct cccgtgaaaa tatcctgctg ttgttattaa aactgcgcac
     3481 ctttatcgcg ctgtttctga ttgtcggctt cttcacgatg accgtgcccg gatttttatc
     3541 cgctggcagc atggtgatta tgattaaaca cattgcgatt aacgcctttc tggcgttggg
     3601 gatcaccttt gtcattatca ccgccggtat cgacctctcg attggcgcca cgctcggtct
     3661 ctgcggaatg atagccggct ggcttatcac caaagggatc gtcctgccga tgttcggcat
     3721 cgccattttt ccaagcgtgt gggtcattgt gcccctggtg ctgctgatag gcgccctgat
     3781 tggcgccgtt aatggctgga tcattacccg ctacaatgtg gcgccgttta tctgcaccct
     3841 cggtaccatg tatgtgctcc gcggagccgc gatgctgacc tctgatggcc aaaccttccc
     3901 cgggctcgcg ggcaatccgc agctgggcaa cacgggtttc gatgaaattg gcgcaggtgc
     3961 gctctttggc atcccgtggg ccatctggct gatgatcctc ctggcgctga tcatcgccta
     4021 tatcgcccgg cgtttgcctt ttggccgcca tgtttatgcg atcggtgaca acgagcgcgc
     4081 cgccgagctt tccggcgtga aagtgaagca aattaaagtg ctggtctaca cgctgtccgg
     4141 tttttgcgcc gccattgccg ggatcgtggt ctccgcgcag ctgctggcca gccatccggc
     4201 taacggtacc gcttttgaga tgaatgctat cgccgccgtc gtactgggcg gaacatcgct
     4261 ggccggcggc cggggaacca ttctgggtac gctgattggt gcgtttgtca tcggttttct
     4321 cgccgacggg ctggtgatga tgggggtgag cgagttctgg cagatggtca tcaaagggat
     4381 cgtgattatt gtggcggtca ttatcgatca gatgcaaaac cggatgcagc agaaagcggc
     4441 ggtggtcgcc cagaaagcgg tcatggagaa taagtaaccg caagacctcc tgtggctcag
     4501 gccacagggg gagcgggcct gactcacgat gcgcctttct ccgaggcgct tcgcaaaatc
     4561 tcatcgaaaa atcctgcccg acggcaagcg gtggtagcat cccgccactc tgctctgcca
     4621 ggcaaggaag ccatgaaaaa acgtccgcac tcgaccccgc acgacagcct gtttaaacgc
     4681 tttttgcgcg acaacgaaac cgcacgcgat tttctggata ttcatctgcc gcccgcgctg
     4741 cggcaactgt gcgacttaag cactctgcac ctggaatccg ggagctttgt tgaggacaac
     4801 ctgcgcgcca gctattccga tattctctac tctctgcaga ccagcaaggg agagggctat
     4861 atctatgtcg tcattgagca tcagagcacc ccggacagcc atatggcgtt cagactcctg
     4921 cgctatgccc tcgcggccat gcaacagcat cttgatcgcg gccataaagc gctgccgctg
     4981 gtaattccca tgctgtttta tcatggcagc atttctccct atcccttttc actgtgctgg
     5041 ctggacgagt tcccacctga ctcaccggca aaacagcttt atctcggggc ctttccgctc
     5101 gtcgatgtga ccgatattcc cgacgacgcc atattacagc atcggcggat cgcgcttctg
     5161 gaactggtcc agaaacacat ccgtcaacgc gatctcagct atatccttca gcagttggtg
     5221 gaggtggtgc tgatgggata cactgaccac cagcagttca aaacgttatt tacctatatg
     5281 tcgctgcatg gcaatagcgc cgacccggaa aactttatcg accagctggt cgaacgtctg
     5341 ccgcaatatg aggataccct gatgacgatt gccgagtacc tgaagcaaaa aggtcgcgaa
     5401 gagggaaaac aacgctggtt acaggaaggc ttgaacgaag gtttacaagc gggtgagcat
     5461 cgcgaagcct gccgcatcgc gctgatgatg ttagagaacg gtatggacac tgaaaccgta
     5521 ttgcggatga ctcgcctcag cgcggacgaa ctggcgacgc tggcgcgcca ggcacgccag
     5581 tcttcacccc cgcttaaccc ttaattaacg cgcgcgcggt cgggaagtcg gtgatcagga
     5641 catcaatata gtcgccctgc aacgcgccgc ggatggcgtt ctctttgtcc acgccgccag
     5701 ccagcgcaat cacctgcgga caacgacgaa tttgatcaag ctccataccg atcaccggat
     5761 cctcatcctg gctcagtacc ggtttgcccg ccgcattata gtaatgcagg cagatatccc
     5821 ccaccgcgcc gcgcgccgcc agaagctgga gcatggtttc attataatag ttaccggaat
     5881 ttttcagcag ctgcgaaggc tccagttcac caataccgac gatggccaca tccacttcgg
     5941 caaatttcgc caccaccgcc gcgacgtccg gactgtttac cagacggctg cgctcctcca
     6001 cggagtgctc aatactctgc gacggcaaca gccaagccgg gcagcctaaa tgcgccgcca
     6061 gctgctgggt taaaatggta gcctgcacgt tgccgttggg accgacgccg cccaacagct
     6121 gtatcacccc ggcggcgcga atgttctgcg gatgcatctc atccaccatg cagcggatcg
     6181 tactgctcca ggacgagatc cccacgaggt cttccggccg cagccgcgtt tcgacatagt
     6241 gcgccgctgc gctgccgatg gcatgcttta cctgactgta actggcgttc tcgcccacat
     6301 ccacgactat cgcctgtcga atgccaaaac gctcctcaat cgccttttcc agatcgacaa
     6361 aaatgtttgt cggctggacc acggtaattt tcaccagccc ctctttctga cagcgggtaa
     6421 gcgcccgtga aacaaaagac tgggacagat ggagcagcga ggcgatctcg gactgctttt
     6481 tattctcgct gtagtaaagc gtggcgatct tcaccagcaa ccgctgttca tcctgcttcg
     6541 acatggcatt cccctctgtt ttctgctcgt tatttttatg catcattgaa tagataacaa
     6601 gcgcagcgcc cttttcccga cgatccaaat gtgatcgttt tctccttttt tagaaaatag
     6661 gccgtacaaa tcgtggacaa accccctcac agggcatatc ttaccaatgt gaataataaa
     6721 tcagtagtga atatatattc aatcacttat taataccttg ttttgtcgac gataaaaggt
     6781 agtcaggatg ggaagtgttt ctttaccctg cttgaatatt tattcacaca agaatttact
     6841 ttcaagaggt gttttatgaa tccgttttca ctctccgtta aggagttaga acaaaaagca
     6901 cgcgccatcc gccgccgcat catcgtctta aatgcggaaa gcccggcagg cggccacacc
     6961 ggtgccgatc tgtcacaagt cgaacttctg accgccctct attttcgtat ccttaactgc
     7021 tcccctgcgc gaaaagagag tgacgaccgc gatatctata ttcagtcgaa ggggcacgct
     7081 gtcggtggtt actactgcgt gctggccgaa gcaggcttta ttcccgttga ctggctggca
     7141 acctatcaac acgccgactc ggctctgcca ggacacccgg taaagcacaa aacgccaggt
     7201 attgagctca ataccggtgc gctgggccat ggtctgcccg tggcggtagg cattgcgctg
     7261 gcagcgaaac gcgataacaa cccgcgtcgc gtatttgtcg tcaccggcga tggcgaactg
     7321 gcggagggca gcaactggga ggccgcgctg gtcgccgccc actaccaact ggataacctt
     7381 attattatca acgacaaaaa taatctgcag ctggccggtg cgaccaaaga gatcatgaat
     7441 accgatccgc tggatgaaaa atggcgcgct ttcggcatgg aggttacgca gtgcaacggc
     7501 aacgatatgg cggaggtggt cgccaccctt gagggccttc agccgaacgg gaaaccacac
     7561 gtcgtgattg ccaataccac caaaggcgca ggtatttcct ttattcaggg acgccccgaa
     7621 tggcatcacc gggtaccgaa aggagaagaa attgaactgg cgctggagga actgaaagat
     7681 gagtaatagc gaacatctcg ccacggtgat ggtgaatgcc tttattgatg ccgtagaccg
     7741 cggcgtggat ctggtgccgg tggtggccga ctccacctca acggcgaaaa ttgctccgtt
     7801 tatcaaaaga ttccctggcc ggctggtcaa cgtcggcatc gccgagcaga cgctggttgg
     7861 cgctgccgcc ggtctggcgc tgggggggaa agtggccgtg acctgcaacg ccgcgccatt
     7921 cctcatctca cgagccaatg agcagattaa ggtcgacgtt tgctacaaca acaccaacgt
     7981 caaactgttc gggctgaacg cgggcgccag ctacggtcca ctggccagca cccaccacag
     8041 tattgacgat atcgccattc tgcgcggttt tggcaatatt gaaatttacg cgccgtccag
     8101 tcccggcgag tgccggcaga ttattgatta tgcccttgcc cacgtcgggc cagtgtatat
     8161 ccgcctcgac ggtaaagcgc tgccggaact gcatgatgaa cgttaccggt ttgttccggg
     8221 caacattgat gtgctgcgtc tggggcgcga tattgcgctg gttgccatgg gctcaacggt
     8281 acatgaaatt gtggaagccg ccgcacaact cgctgcagaa ggtattgacg ccaccgttat
     8341 cagtgtccca tctattcgtc cttgtgatac ccaggcgcta ctggcggcaa tccagtcctg
     8401 tccggccgca atcacggtgg aagaacacaa cgtcaacggc ggcgtcggga gcctggtggc
     8461 ggaagtgctg gccgaggccg ggtgcgctat cccgttgcgg cgcttaggta tccctgacgg
     8521 gcaatacgcc attgccgccg atcgcgccgc cacgcgcgcg cgccatgaaa ttgatgccgc
     8581 cggggtggtg aagcacgccc gcaagctgct cacaaaaaaa gcatgctgaa aaataacaag
     8641 aacatcttac tggagagaac gcaatgtccc gtattcctca acaactcacc atgggcgtca
     8701 ttattggcaa ccggggattt ttccccagct acctggtcgc cgaagcgcgc gaacaggcgg
     8761 tagcgctgtt tagccgcctt gggattaaca ctattatgct tgatccatcc cagacggaac
     8821 tgggtggcgt ggaaacccgg caggatgcca aaatttgcgc cgagctgttc cgcacccacc
     8881 gcgacaaaat tcacggtgtc gtggtgctgt tacccaactt tggtgatgaa aaagccatcg
     8941 ccgaaacgtt gcgcctctcc ggtctcaacg tcccggtgct tattcaggcc gaagaggata
     9001 atctggataa aatggggttg tcgactcgcc gcgatagctt ttgcggcaaa atttcccttt
     9061 gcaacaacct gcgccagtac ggtatcccgt ttacgctgac cacccagcac gtttgcgcgc
     9121 ttagcggcga ggtgtttgag caggatctcc ggcgcttcac gcagatatgt cgcgtggtga
     9181 acagtatgcg cggcgtgcgc gttggcgcga ttggcgcccg tccagcgggc tttaacaccg
     9241 ttcgctacag tgaaaaactg ctcgaacgtt taggcatagc agtggaaacg ttagatctat
     9301 cagaggtatt tacccggatt aaagccctgc gtgatgacga tattcgtgtc gatgagaagc
     9361 gccgcctgct gatcgataat gccgacgcca gcggtattcc ggcagataaa ctgatcacca
     9421 tggcgaaact gtttgtggtc ctgagcgagt ggattgttgc caacgacatc gacaccaccg
     9481 caattcagtg ctggacctcg ctgcaggaaa atctggggat taacgtctgc tccatcatga
     9541 gcgtgatgtc cggacaactg atgccaagcg cctgtgaggt cgatgtcatg ggcgcgctct
     9601 ccatgtacgc gctcgccagc agcaacctga gccccgcctc gatcgcagac tggaacaata
     9661 acttcggcga cgatcgtgat aaatgtgtgc tgttccattg tgggaacttt gcctcggcca
     9721 gccttgagtc gccgcacatg ggaacggccg atattatcgg caccaccgtc ggcaaagaaa
     9781 acacctgcgg tgccgtgcac ggtcgcatga aaagcggcgc gctgacctat tttcgcctca
     9841 gcaccgacga cctgactggc gaaatcaagg cctacgtcgg agaaggtcag tcagttgacg
     9901 atcccctcga tacggtaggc tgtcgggcgg tcattcaggt tccccacctg gaaaatctgc
     9961 tgtcgtggat ctgccgcaac ggctttgagc accatgtcgc gatgaaccat tctgccagtg
    10021 ccgcaatttt gcacgaggca tttacgcgct acctgggcgt atcgacctat ctccaccagt
    10081 aaggccggag gccgctatgt cggtaaacaa ggatattatt attgccctcg atgagggcac
    10141 aaccaatgcc aaagccgttg ccttcgacag ccacgggcgg gtaatcgcgc aattttcccg
    10201 cgcgcttgag atcgctacgc cgcaggaagg atgggttgaa cagtcagcgg agcttctgct
    10261 tgccgcgtcg ctggaggcga tttctcgcac agtggccgcc gttggcgcgg agcgtgtggc
    10321 ggccctggcg atcagcaacc agcgcgaaac cgtcgtgggc tggtatcggg aaacgggcga
    10381 ggccatagcg cctgccctga gctggcaatg ttcacgtact gccgcatttt gccacatgct
    10441 gcgtgaacaa ggtcatgagc cgcagatcaa ggcggtaacc ggcctgccag tcgccccgct
    10501 cttttccgcc tcgaaaatgc gctggctgct ggaccacact ccggatggtc tgaaccgagc
    10561 gaaagatggc gagatttgcc tcggtacggt ggatagctgg ctactctggc acctgacgca
    10621 aggccagcat ttttgttgtg attatgcaaa cgcgtctcgt acacagctca tgaatttgca
    10681 aacagcggac tgggataccg atatgctcgc cctgtttggc attccgtgtg cagcactccc
    10741 ggtgataaaa ccttcaagtg gactgtttgg ttacaccgct ggtttagcca ccctccctga
    10801 tgggatcccg gtaatggcga tgattggcga ttcgcatgcc gcccttttcg cccacggtct
    10861 gggcgccacc ggttgtgtta aagccactta cggtacaggg acctcggtga tggcgcccgt
    10921 cgattcggtg gcgtttcacg tcagcaatct cgccaccacg gtggcctggc acgacggaga
    10981 aaagctggtc tacgcactcg aggggaacat tccccatacc ggcgatgcgg tggcgtggat
    11041 ggccgacagt accggattga gcgaacgctc tcccgccgaa ctggcccagg cgctgaatgc
    11101 tctgcctcgt tcggtagatt ccaccttagg cgtctttttt gtgccggcgc tcaccggcat
    11161 gggcgcaccc tggtgggacg ataaggcccg cggtttgatc catggattaa gccggggcgt
    11221 gaagcgggcc catctcattc gtgccgcgct agagtcaatt acctaccaga ttgccgatgt
    11281 aatcactgcg atgcgtgccc atcatggctt tacgctcaac acgctgctgg tggatggggg
    11341 acccaccaaa aacgactggt taatgcagta ccaggccgac ctgctggggt gtccggtgat
    11401 gcgcagcgat gtggccgagc tgtcggcgac cggcgcggca ctgctggcgc gtaaagcgtt
    11461 gcacaagctg acggtggcag agcttcagcc ctttttacca gaacacatca cttatgcacc
    11521 agacctgctc cggcatcatc ggcttgtgca gcgatggcag tcctggcaac acgcggtgaa
    11581 gctggcaaga cgctgagcgc aacccagccg ggcgataacg tcttcgtccg gctgcaatcc
    11641 aacgc
//
