LOCUS       CP102117               16813 bp    DNA     circular BCT 07-AUG-2022
DEFINITION  Shigella sonnei strain 1527854 plasmid p1527854_4, complete
            sequence.
ACCESSION   CP102117
VERSION     CP102117.1
DBLINK      BioProject: PRJNA315192
            BioSample: SAMN23134804
KEYWORDS    .
SOURCE      Shigella sonnei
  ORGANISM  Shigella sonnei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Shigella.
REFERENCE   1  (bases 1 to 16813)
  AUTHORS   Greig,D.R., Painset,A. and Jenkins,C.
  TITLE     Nanopore sequencing of Shigella species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16813)
  AUTHORS   Greig,D.R., Painset,A. and Jenkins,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2022) Gastrointestinal Bacteria Reference Unit,
            Public Health England, 61 Colindale Avenue, London, London NW9 5EQ,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-JAN-2022
            Assembly Method                   :: Flye v. 2.9
            Assembly Name                     :: 1527854
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 60.4x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 08/01/2022 14:42:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.2
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,345
            CDSs (total)                      :: 5,219
            Genes (coding)                    :: 4,343
            CDSs (with protein)               :: 4,343
            Genes (RNA)                       :: 126
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 95
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 876
            CDSs (without protein)            :: 876
            Pseudo Genes (ambiguous residues) :: 0 of 876
            Pseudo Genes (frameshifted)       :: 365 of 876
            Pseudo Genes (incomplete)         :: 526 of 876
            Pseudo Genes (internal stop)      :: 132 of 876
            Pseudo Genes (multiple problems)  :: 136 of 876
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..16813
                     /organism="Shigella sonnei"
                     /mol_type="genomic DNA"
                     /strain="1527854"
                     /host="Homo sapiens"
                     /db_xref="taxon:624"
                     /plasmid="p1527854_4"
                     /geo_loc_name="United Kingdom: United Kingdom"
                     /collection_date="2021-11"
                     /collected_by="PHE"
                     /note="genotype: ST245"
     gene            complement(551..991)
                     /locus_tag="LOP30_26630"
     CDS             complement(551..991)
                     /locus_tag="LOP30_26630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="UUM42354.1"
                     /translation="MAWHTVQETLKLTGKSRSQLYRDMAKGLVSYRTGKNDRREFETSE
                     LIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKLDALQQTVTLMLEDKMARE
                     AENRLRNEEREQLQAEISRLADALAQEKKRGFWSRLFRSGSE"
                     /name="entry exclusion protein 1"
     gene            1209..1598
                     /locus_tag="LOP30_26635"
     CDS             1209..1598
                     /locus_tag="LOP30_26635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UUM42355.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGHD
                     NSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANNVR
                     VGVTGTGWQCLATAGISAEGKRTFR"
                     /name="hypothetical protein"
     gene            1642..1830
                     /locus_tag="LOP30_26640"
                     /pseudo=""
     CDS             1642..1830
                     /locus_tag="LOP30_26640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(1797..2996)
                     /gene="tet(A)"
                     /locus_tag="LOP30_26645"
     CDS             complement(1797..2996)
                     /gene="tet(A)"
                     /locus_tag="LOP30_26645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(A)"
                     /protein_id="UUM42356.1"
                     /translation="MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHY
                     GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI
                     VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPF
                     FAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIM
                     QLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM
                     LGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSL
                     AALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRRGLWRNSSNSRCT
                     "
                     /name="tet(A)"
     gene            3102..3752
                     /gene="tetR(A)"
                     /locus_tag="LOP30_26650"
     CDS             3102..3752
                     /gene="tetR(A)"
                     /locus_tag="LOP30_26650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="UUM42361.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            complement(3784..4026)
                     /locus_tag="LOP30_26655"
     CDS             complement(3784..4026)
                     /locus_tag="LOP30_26655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="UUM42357.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="relaxase"
     gene            complement(4332..5168)
                     /locus_tag="LOP30_26660"
     CDS             complement(4332..5168)
                     /locus_tag="LOP30_26660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="UUM42358.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     gene            complement(5168..5971)
                     /gene="aph(3'')-Ib"
                     /locus_tag="LOP30_26665"
     CDS             complement(5168..5971)
                     /gene="aph(3'')-Ib"
                     /locus_tag="LOP30_26665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="UUM42359.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRR
                     GELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPS
                     MGQQLGAVHSLSVDQCQFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARV
                     ERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIA
                     NAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
                     /name="aph(3'')-Ib"
     gene            complement(6032..6848)
                     /gene="sul2"
                     /locus_tag="LOP30_26670"
                     /pseudo=""
     ARG             complement(5959..6848)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="109.23"
     gene            8037..8186
                     /locus_tag="LOP30_26675"
     CDS             8037..8186
                     /locus_tag="LOP30_26675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UUM42360.1"
                     /translation="MPSEYDEQLDSTDTQLPGEYDLFDLMAQVTEENLHAPVDFGSPVG
                     REAL"
                     /name="hypothetical protein"
     gene            complement(8939..9376)
                     /locus_tag="LOP30_26680"
                     /pseudo=""
     CDS             complement(8939..9376)
                     /locus_tag="LOP30_26680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005119689.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /name="entry exclusion protein 1"
     gene            9593..9982
                     /locus_tag="LOP30_26685"
     CDS             9593..9982
                     /locus_tag="LOP30_26685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UUM42348.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGHD
                     NSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANNVR
                     VGVTGTGWQCLATAGISAEGKRTFR"
                     /name="hypothetical protein"
     gene            10026..10214
                     /locus_tag="LOP30_26690"
                     /pseudo=""
     CDS             10026..10214
                     /locus_tag="LOP30_26690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     ARG             complement(10185..11380)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1801..2996)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11486..12136
                     /gene="tetR(A)"
                     /locus_tag="LOP30_26700"
                     /pseudo=""
     CDS             11486..12136
                     /gene="tetR(A)"
                     /locus_tag="LOP30_26700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /name="tetR(A)"
     gene            complement(12168..12411)
                     /locus_tag="LOP30_26705"
                     /pseudo=""
     CDS             complement(12168..12411)
                     /locus_tag="LOP30_26705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
                     /name="relaxase"
     gene            complement(12717..13553)
                     /locus_tag="LOP30_26710"
     CDS             complement(12717..13553)
                     /locus_tag="LOP30_26710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="UUM42350.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     ARG             complement(5172..5971)
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.63"
                     /coverage="100.0"
     ARG             complement(13557..14356)
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.63"
                     /coverage="100.0"
     ARG             complement(14421..15232)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(6088..6848)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="93.73"
     gene            16459..16608
                     /locus_tag="LOP30_26725"
     CDS             16459..16608
                     /locus_tag="LOP30_26725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UUM42353.1"
                     /translation="MPSEYDEQLDSTDTQLPGEYDLFDLMAQVTEENLHAPVDFGSPVG
                     REAL"
                     /name="hypothetical protein"
     ARG             complement(4336..5168)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12721..13553)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          7922..8008
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.864"
                     /coverage="99.0"
                     /evalue="1.15e-36"
     Typing          16250..16424
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="93.75"
                     /coverage="100.0"
                     /evalue="5.6599999999999995e-68"
     Typing          complement(7300..7845)
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.054"
                     /coverage="90.0"
                     /evalue="0.0"
     Typing          complement(15776..16267)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.154"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggcgggtg atttacgcag gttaagggga gatcgtgaca aaaaaagcgt tcctcactgt
       61 atcgttcatg cctgcatgaa cgggttattc ttcctgacta cagaattaca tcgctccttc
      121 agttcataca tcacttatac atcactttta catcacttat acatcacttt tacatcattc
      181 cttcagctca tacgtcactt tcatcctctg tgccatttgt acatcacccc cttcctgaac
      241 gtgctgacag cgggttttcc ggctgcgccg gcaacgcttc acggccacgc aataaattgc
      301 gtccccgttc accgttttcg gatgggaaga acgccggaaa caggacttac cccggctgaa
      361 tggtgtgaat ttccgcgcta tgcacttgtg cgcatactca tgcatgccgt aaaaacagag
      421 cctgcgcgtt tctggcgggt tttcgggtgg tttgttgcct gttttaccgg tttcccgtca
      481 gaaacgccct gagggcctct caggcggtgc tgataacaga tgttatggta aatcagagtc
      541 acctgcactg ttactctgaa ccggagcgaa acagccgcga ccagaatccc cgcttttttt
      601 cctgtgccag cgcgtcagcc agacggctaa tttcggcctg tagttgttcc ctctcctcat
      661 ttcgcaggcg gttttctgct tcccgcgcca tcttgtcttc aagcattagg gtaacagtct
      721 gctgcagagc gtccagtttc tgctgaatga cgtctagctg agcattttcc gcctggctaa
      781 cgacagattt ggagtgtccc tccttgtgcc tttttggtgt ctcagaagtg cgcagctcgc
      841 cataggcccg aatcagttca ctggtctcga actcccggcg atcatttttt cctgtgcgat
      901 agctgacaag gcctttagcc atgtcacgat ataattgcga gcgcgacttt cctgttaatt
      961 tcagtgtctc ttgaactgtg tgccatgcca taaaagtgac agtgtctcct gtgtgtaccg
     1021 tattgtaaca gcagaacata ttactgtttt aacacaaaag gtctgaggct gcccgtgagg
     1081 cgtgaaaaat acacaaaaaa cctgttgacg gtgtggtttt gacgggcgta gtatttcgaa
     1141 tactgtatat aaacacattg ttataaatac agtttttgct gtttttaaaa gtcaaagagg
     1201 ataattttat gagtacagag ttaaatagcg gtactgtcgg tggttttggt cacatgggac
     1261 caaatgaccc ctacaatgat ggtcatagcg gctctggaag ttcgggaggt agttttaacg
     1321 gtggtggtaa tggtggccat gataatagta gtggttcatc ttatactgca tcctttggtc
     1381 tcatcactgg ccgacacccg ataactgtcc caggtacgaa gaatattaat tctgtcgatc
     1441 tttctgctgt cattaataac attatacatc atgaaggtgc acgcaataac atgtacctag
     1501 atactgcgaa caatgtaaga gtgggagtga cgggcactgg ctggcaatgt ctagcaacgg
     1561 caggcatttc ggctgagggt aaaagaactt tccgctaagc gatagactgt atgtaaacac
     1621 agtattgcaa ggacgcggaa catgcctcat gtggcggcca ggacggccag ccgggatcgg
     1681 gatactggtc gttaccagag ccaccgaccc gagcaaaccc ttctctatca gatcgttgac
     1741 gagtattacc cggcattcgc tgcgcttatg gcagagcagg gaaaggaatt gccgggctat
     1801 gtgcaacggg aatttgaaga atttctccaa agcccgcgac gcagcgccgg caggcagagc
     1861 aagtagaggg cagcgcctgc aatccatgcc cacccgttcc acgttgttat agaagccgca
     1921 tagatcgccg tgaagaggag gggtccgacg atcgaggtca ggctggtgag cgccgccagt
     1981 gagccttgca gctgcccctg acgttcctca tccacctgcc tggacaacat tgcttgcagc
     2041 gccggcattc cgatgccacc cgaagcaagc aggaccatga tcgggaacgc catccatccc
     2101 cgtgtcgcga aggcaagcag gatgtagcct gtgccgtcgg caatcattcc gagcatgagt
     2161 gcccgccttt cgccgagccg ggcggctaca gggccggtga tcattgcctg ggcgagtgaa
     2221 tgcagaatgc caaatgcggc aagcgaaatg ccgatcgtgg tcgcgtccca gtgaaagcga
     2281 tcctcgccga aaatgaccca aagcgcggcc ggcacctgtc cgacaagttg catgatgaag
     2341 aagaccgcca tcagggcggc gacgacggtc atgccccggg cccaccggaa cgaagcgagc
     2401 gggttgagag cctcccggcg taacggccgg cgttcgcctt tgtgcgactc cggcaaaagg
     2461 aaacagcccg tcaggaaatt gaggccgttc aaggctgccg cggcgaagaa cggagcgtgg
     2521 ggggagaaac cgcccatcag cccaccgagc acaggtcccg cgaccatccc gaacccgaaa
     2581 caggcgctca tgaagccgaa gtgccgcgcg cgctcatcgc catcagtgat atcggcaata
     2641 taagcgccgg ctaccgcccc agtcgccccg gtgatgccgg ccacgatccg cccgatatag
     2701 agaacccaaa ggaaaggcgc cgtcgccatg atggcgtagt cgacagcagc gccggccagc
     2761 gagacgagca agaccggccg ccgcccgaaa cgatccgaca gcgcgcccag cacaggtgcg
     2821 caggcaaatt gcatcaacgc atacagcgcc agcagaatgc catagtgggc ggtgacgtcg
     2881 ttcgagtgaa ccagatcgcg caggaggccc ggcagcaccg gcataatcag gccgatgccg
     2941 acagcgtcga gcgcgacagt gctcagaatt acgatcaggg gtctgttggg tttcacgtct
     3001 ggcctccgga ccagcctccg ctggtccgat tgaacgcgcg gattctttat cactgataag
     3061 ttggtggaca tattatgttt atcagtgata aagtgtcaag catgacaaag ttgcagccga
     3121 atacagtgat ccgtgccgcc ctggacctgt tgaacgaggt cggcgtagac ggtctgacga
     3181 cacgcaaact ggcggaacgg ttgggggttc agcagccggc gctttactgg cacttcagga
     3241 acaagcgggc gctgctcgac gcactggccg aagccatgct ggcggagaat catacgcatt
     3301 cggtgccgag agccgacgac gactggcgct catttctgat cgggaatgcc cgcagcttca
     3361 ggcaggcgct gctcgcctac cgcgatggcg cgcgcatcca tgccggcacg cgaccgggcg
     3421 caccgcagat ggaaacggcc gacgcgcagc ttcgcttcct ctgcgaggcg ggtttttcgg
     3481 ccggggacgc cgtcaatgcg ctgatgacaa tcagctactt cactgttggg gccgtgcttg
     3541 aggagcaggc cggcgacagc gatgccggcg agcgcggcgg caccgttgaa caggctccgc
     3601 tctcgccgct gttgcgggcc gcgatagacg ccttcgacga agccggtccg gacgcagcgt
     3661 tcgagcaggg actcgcggtg attgtcgatg gattggcgaa aaggaggctc gttgtcagga
     3721 acgttgaagg accgagaaag ggtgacgatt gatcaggacc gctgccggag cgcaacccac
     3781 tcactacagc agagccatgt agacaacatc ccctccccct ttccaccgcg tcagacgccc
     3841 gtagcagccc gctacgggct ttttcatgcc ctgccctagc gtccaagcct cacggccgcg
     3901 ctcggcctct ctggcggcct tctggcgctc ctgctgcggc gtccgctcgt gggccgtggc
     3961 gcgggtccgc gcgccggcct cgtgcgcctg gcgctcgcgg gcgaggtcca gggcggccgt
     4021 cttcacgttc tgccttgcgc agatgagata gatctagcgt ggactcaagg ctctcgcgaa
     4081 tggctcgcgt tggaaacttt cattgacact tgaggggcac cgcagggaaa ttctcgtcct
     4141 tgcgagaacc ggctatgtcg tgctgcgcat cgagcctgcg cccttggctt gtctcgcccc
     4201 tctccgcgtc gctacggggc ttccaggggt cgtttgcggg aaggggcgga atcctacgct
     4261 aaggctttgg ccagcgatat tctccggtga gattgatgtg ttcccagggg ataggagaag
     4321 tcgcttgata tctagtatga cgtctgtcgc acctgcttga tcgcggccgc gatagctaga
     4381 tcgcgttgct cctcttctcc atccgcgttc caagctgcgg aaaggcaccc ataagcgtac
     4441 gcctggtcga gcaggcgacg cggatcgacg tccagcgcac gagagaatgc gtccgccatc
     4501 tgtgcaatgc gtctaggatc gagacaaagg tcgtctctgt cagccggatc gtagaacata
     4561 ttggcggcgc caaagcccac ttcaccgacc agaccgacgg gatctatcac cagccagccg
     4621 cgactggaga acatgatgtt ttcatgatgc agatcgccat gtagcccacg cagttccgag
     4681 gcattgctca tcatttgatc ggctataatc gccgcgtgga cgtagtcagt ttgacaacct
     4741 gcgttttgat catcgcgcgc ccgctgaaac aaagctgcaa agcgatcccg gatcgggaga
     4801 agggcagaag gcaggggttc ctcagatgcg gcatacagct tcgccattag ttccgctgca
     4861 atttcggtcg cctggtagtc gccgtgctcg gcaacgatgt gagagagcat tcgctccccg
     4921 gcatattcga gcaacatcag attgttctca cgaccgagca accggactgc tcccctccca
     4981 ttgcgccata ccagatagtc ggccccgcgc agttcatcag caatgtcttc tataggtttc
     5041 aatcccttga cgattgcagg agtcccgtct ggcaatgaaa ctttccaaac gaggctggaa
     5101 aaggtgtccg caatgagaac aggttgcgaa acgtgccaat gagcaggaaa aacaggcggc
     5161 atgaacatca accccaagtc agagggtcca atcgcagata gaaggcaagg cgttcgcggt
     5221 cgggggcttc gatccccaat acattgaata ggacagcgaa ggcgcgctct gcttcatctg
     5281 gcgctgccca gttctcttcg gcgttagcaa tcatgagtgc caaatcggca tagcgatctg
     5341 ctgttccgag ccgcccaagg tcgatcagac ccgtgcattg aagagtttta gggtccacca
     5401 tgaagttcgg catgcaggga tcaccatggc aaacaaccat atcggtgcgc tcttggtcga
     5461 gccgcaccgg tagctctcgt tcgacacgag ccaaaagatc gagctgcggc gtactcttgt
     5521 cctcgtccgg taagaagtcg ggattgacgg cattgcggga caccacatca acggcgcgtc
     5581 cgaacattcg cgacagcctg cgctcaaact gacattgatc aaccgatagg ctgtgaacag
     5641 cgccaagttg ctgccccatt gacggccacg ctttgagcaa atccgctcca gacagatcag
     5701 ccgccggtac tcccggaatt gccgttatca ccaagcatgc accctcctgt tcctcctgcc
     5761 agttgatgac ctcggggcaa gccacacctc gacctttgag ccaaatgagg cggtcacgct
     5821 ctccagcgag ctcaccgcgg cgggaagcag gtgcgatttt cgcgaaggca tgcccgtcac
     5881 cacgtcgaaa aacaaaatca ccagattctc cgcctctgac aggcaaccag tcagaatgcg
     5941 attcaccaaa aaaaatatta gttcgattca atggaggttc cttcagtttt ctgatgaagc
     6001 gcgaatatag agaaatatcc cgaatgtgca gttaacgaat tcttgcggtt tctttcagcg
     6061 ccgccaatac cgccagcccg tcgcgcaagg gggcgcggct cgtgtgtgcg gatgaagtca
     6121 gctccacctg cggcggcggc aagctctgca gcgagtgtcg cggccccgac atcccccgga
     6181 ccacggcctg tgagcgcgcg cagaaaggat ttgcgcgaaa cagacagaag caccggcaaa
     6241 tcgaagcgca gccgcaattc atcgaaccgc gccagcaccg agagcgaggt ttcgggagca
     6301 gcccccagaa aaaaccccat gccgggatca aggacaaggc ggttgcgttt gataccggca
     6361 cccgtcagcg ccgcgatgcg cgcgtcaaag aacgccgcaa tgtgatccat gatgtcgcca
     6421 gcgggtgcct cgcgccgatc tgcctgcccg tcttgcaccg aatgcataac gacgagtttg
     6481 gcagatgatt tcgccaattg cggatagaac gcagcgtctg gaaaaccgcg aatatcattg
     6541 agataggcca caccacgcga caaggcatag gcttgcgtcg cgggttgata actgtcgagc
     6601 gagacgggaa tgccatctgc cttgagcgcg tccagcaccg gcgcgatacg cgcgatttct
     6661 gtgtcggacg aaacaggcgc ggcgtcggga ttgctggatg ccggaccgag gtcgatcaca
     6721 tctgccccct cggccatcag cttacgcgcc tgcgcaatgg ctgcgtctgg cgccagatac
     6781 cggcctccat cggagaaact gtccgaggtt atgttgacga tgccgaaaat gatgagcgat
     6841 ttattcatgg gggcttctat aataataata atcgagcatg agtctcatac ggatgctcgg
     6901 gtcgaaaggg aatccccagg cgagtaacct gtttgcggtg atccgtttca tgatgatgta
     6961 tctgtagcat tttggaaata aatatatcat ctctcaataa gtagatatat ttatcttttt
     7021 tgcttctttg gtgctgcaag tcaccaatac gagggaaacc tgttacggag cggtttaacc
     7081 gtaatcaaca gtgactggtg tcatgttcgg aagattaatt gatagtaatc tacaaaggat
     7141 cttcttgaga tccttttcaa tgaatcgtaa tctcttgctc tgtaaacgaa aaaaccgcct
     7201 ggggaggcgg tttgttcgaa ggttaagtca gttggggaac tgcttaaccc ggtaacaggg
     7261 ttcacgagac cgccattacc aaaactgttc tttcagtgta gccgcagtca ggcctctact
     7321 tcaagacctc ttaatctatc ttctcgtgca ctcctgttac taatggctgc tgccagtggc
     7381 gttttgtcgt gtctttccgg gttggactca agatgatagt taccggataa ggcgcagcag
     7441 tcggactgaa cggggggttc gtgcatacag tccagccagg agcgaactgc cttcgcggaa
     7501 ctgagtgtca ggcgtggaat gagataaacg cggccataac agcggaatga caccggtaaa
     7561 ccgaaaggca ggaatgcggg gagcgcacga gggagctacc agggggaaac gcctgggatc
     7621 tttatagtcc tgtcgggttt cgccaccact gatttgagcg tcagattttg cgatgcttgt
     7681 caggggggcg gagcctatgg aaaaacggct tcgccgcggc cttatctctt ctttgctaag
     7741 tccttcctgg tatctcccag gaaatttccg ccccgcctgt aagccggcac cgctcgccgc
     7801 agccgaacga ccgagcgtag cgagtcagtg agcgaggaag cggaaaagcg cctggactgg
     7861 cattttctcc ttacgcatct gtgcggcatt tcacacccgg acatggcgca cttttcatac
     7921 aatccgcact gatgccgcat ggttaagcca gtatacactc cgctatcgct acgtgactgg
     7981 gtcagggctg cgccccgaaa cccgctaaca acctctcagc tactggatat caccccatgc
     8041 catctgaata tgatgaacaa ctggattcga ctgatacgca gcttcccggc gaatatgacc
     8101 tttttgattt aatggcgcag gttactgaag agaacctgca tgcccctgtg gattttgggt
     8161 cgcctgtcgg ccgggaagcg ttatagcttt ttcgcttgcc cgcgtacgtg gtaatactcc
     8221 ggtattacct tttatttctt tattttcatg taattacagt ggatttttaa tacccgggta
     8281 ttactcgtga aaacgaaata ttcctttttt tcttttaatt catgcagttg cgatgaaaat
     8341 cgcggctgcg ttaggtgtat gaccattttg aggttgaaaa ataatcaacc atggcgggtg
     8401 atttacgcag gttaagggga gatcgtgaca aaaaagcgtt cctcactgta tcgttcatgc
     8461 ctgcatgaac gggttattct tcctgactac agaattacat cgctccttca gttcatacat
     8521 cacttataca tcacttttac atcacttata catcactttt acatcattcc ttcagctcat
     8581 acgtcacttt catcctctgt gccatttgta catcaccccc ttcctgaacg tgctgacagc
     8641 gggttttccg gctgcgccgg caacgcttca cggccacgca ataaattgcg tccccgttca
     8701 ccgttttcgg atgggaagaa cgccggaaac aggacttacc cggctgaatg gtgtgaattt
     8761 ccgcgctatg cacttgtgcg catactcatg catgccgtaa aaacagagcc tgcgcgtttc
     8821 tggcgggttt tcgggtggtt tgttgcctgt tttaccggtt tcccgtcaga aacgccctga
     8881 gggcctctca ggcggtgctg ataacagatg ttatggtaaa tcagagtcac ctgcactgtt
     8941 actctgaacc ggagcgaaac agccgcgacc agaatccccg cttttttcct gtgccagcgc
     9001 gtcagccaga cggctaattt cggcctgtag ttgttccctc tcctcatttc gcaggcggtt
     9061 ttctgcttcc cgcgccatct tgtcttcaag cattagggta acagtctgct gcagagcgtc
     9121 cagtttctgc tgaatgacgt ctagctgagc attttccgcc tggctaacga cagatttgga
     9181 gtgtccctcc ttgtgccttt tggtgtctca gaagtgcgca gctcgccata ggcccgaatc
     9241 agttcactgg tctcgaactc ccggcgatca tttttcctgt gcgatagctg acaaggcctt
     9301 tagccatgtc acgatataat tgcgagcgcg actttcctgt taatttcagt gtctcttgaa
     9361 ctgtgtgcca tgccataaaa gtgacagtgt ctcctgtgtg taccgtattg taacagcaga
     9421 acatattact gttttaacac aaaaggtctg aggctgcccg tgaggcgtga aaaatacaca
     9481 aaaacctgtt gacggtgtgg ttttgacggg cgtagtattt cgaatactgt atataaacac
     9541 attgttataa atacagtttt tgctgttttt aaaagtcaaa gaggataatt ttatgagtac
     9601 agagttaaat agcggtactg tcggtggttt tggtcacatg ggaccaaatg acccctacaa
     9661 tgatggtcat agcggctctg gaagttcggg aggtagtttt aacggtggtg gtaatggtgg
     9721 ccatgataat agtagtggtt catcttatac tgcatccttt ggtctcatca ctggccgaca
     9781 cccgataact gtcccaggta cgaagaatat taattctgtc gatctttctg ctgtcattaa
     9841 taacattata catcatgaag gtgcacgcaa taacatgtac ctagatactg cgaacaatgt
     9901 aagagtggga gtgacgggca ctggctggca atgtctagca acggcaggca tttcggctga
     9961 gggtaaaaga actttccgct aagcgataga ctgtatgtaa acacagtatt gcaaggacgc
    10021 ggaacatgcc tcatgtggcg gccaggacgg ccagccggga tcgggatact ggtcgttacc
    10081 agagccaccg acccgagcaa acccttctct atcagatcgt tgacgagtat tacccggcat
    10141 tcgctgcgct tatggcagag cagggaaagg aattgccggg ctatgtgcaa cgggaatttg
    10201 aagaatttct ccaaagcccg cgacgcagcg ccggcaggca gagcaagtag agggcagcgc
    10261 ctgcaatcca tgcccacccg ttccacgttg ttatagaagc cgcatagatc gccgtgaaga
    10321 ggaggggtcc gacgatcgag gtcaggctgg tgagcgccgc cagtgagcct tgcagctgcc
    10381 cctgacgttc ctcatccacc tgcctggaca acattgcttg cagcgccggc attccgatgc
    10441 cacccgaagc aagcaggacc atgatcggga acgccatcca tccccgtgtc gcgaaggcaa
    10501 gcaggatgta gcctgtgccg tcggcaatca ttccgagcat gagtgcccgc ctttcgccga
    10561 gccgggcggc tacagggccg gtgatcattg cctgggcgag tgaatgcaga atgccaaatg
    10621 cggcaagcga aatgccgatc gtggtcgcgt cccagtgaaa gcgatcctcg ccgaaaatga
    10681 cccaaagcgc ggccggcacc tgtccgacaa gttgcatgat gaagaagacc gccatcaggg
    10741 cggcgacgac ggtcatgccc cgggcccacc ggaacgaagc gagcgggttg agagcctccc
    10801 ggcgtaacgg ccggcgttcg cctttgtgcg actccggcaa aaggaaacag cccgtcagga
    10861 aattgaggcc gttcaaggct gccgcggcga agaacggagc gtggggggag aaaccgccca
    10921 tcagcccacc gagcacaggt cccgcgacca tcccgaaccc gaaacaggcg ctcatgaagc
    10981 cgaagtgccg cgcgcgctca tcgccatcag tgatatcggc aatataagcg ccggctaccg
    11041 ccccagtcgc cccggtgatg ccggccacga tccgcccgat atagagaacc caaaggaaag
    11101 gcgccgtcgc catgatggcg tagtcgacag cagcgccggc cagcgagacg agcaagaccg
    11161 gccgccgccc gaaacgatcc gacagcgcgc ccagcacagg tgcgcaggca aattgcatca
    11221 acgcatacag cgccagcaga atgccatagt gggcggtgac gtcgttcgag tgaaccagat
    11281 cgcgcaggag gcccggcagc accggcataa tcaggccgat gccgacagcg tcgagcgcga
    11341 cagtgctcag aattacgatc aggggtctgt tgggtttcac gtctggcctc cggaccagcc
    11401 tccgctggtc cgattgaacg cgcggattct ttatcactga taagttggtg gacatattat
    11461 gtttatcagt gataaagtgt caagcatgac aaagttgcag ccgaatacag tgatccgtgc
    11521 cgcccctgga cctgttgaac gaggtcggcg tagacggtct gacgacacgc aaactggcgg
    11581 aacggttggg ggttcagcag ccggcgcttt actggcactt caggaacaag cgggcgctgc
    11641 tcgacgcact ggccgaagcc atgctggcgg agaatcatac gcattcggtg ccgagagccg
    11701 acgacgactg gcgctcattt ctgatcggga atgcccgcag cttcaggcag gcgctgctcg
    11761 cctaccgcga tggcgcgcgc atccatgccg gcacgcgacc gggcgcaccg cagatggaaa
    11821 cggccgacgc gcagcttcgc ttctctgcga ggcgggtttt tcggccgggg acgccgtcaa
    11881 tgcgctgatg acaatcagct acttcactgt tggggccgtg cttgaggagc aggccggcga
    11941 cagcgatgcc ggcgagcgcg gcggcaccgt tgaacaggct ccgctctcgc cgctgttgcg
    12001 ggccgcgata gacgccttcg acgaagccgg tccggacgca gcgttcgagc agggactcgc
    12061 ggtgattgtc gatggattgg cgaaaaggag gctcgttgtc aggaacgttg aaggaccgag
    12121 aaagggtgac gattgatcag gaccgctgcc ggagcgcaac ccactcacta cagcagagcc
    12181 atgtagacaa catcccctcc cctttccacc gcgtcagacg cccgtagcag cccgctacgg
    12241 gctttttcat gccctgccct agcgtccaag cctcacggcc gcgctcggcc tctctggcgg
    12301 ccttctggcg ctcctgctgc ggcgtccgct cgtgggccgt ggcgcgggtc cgcgcgccgg
    12361 ctcctcgtgc gcctggcgca cgcgggcgag gtccagggcg gccgtcttca cgttctgcct
    12421 tgcgcagatg agatagatct agcgtggact caaggctctc gcgaatggct cgcgttggaa
    12481 actttcattg acacttgagg ggcaccgcag ggaaattctc gtccttgcga gaaccggcta
    12541 tgtcgtgctg cgcatcgagc ctgcgccctt ggcttgtctc gcccctctcc gcgtcgctac
    12601 ggggcttcca ggggtcgttt gcgggaaggg gcggaatcct acgctaaggc tttggccagc
    12661 gatattctcc ggtgagattg atgtgttccc aggggatagg agaagtcgct tgatatctag
    12721 tatgacgtct gtcgcacctg cttgatcgcg gccgcgatag ctagatcgcg ttgctcctct
    12781 tctccatccg cgttccaagc tgcggaaagg cacccataag cgtacgcctg gtcgagcagg
    12841 cgacgcggat cgacgtccag cgcacgagag aatgcgtccg ccatctgtgc aatgcgtcta
    12901 ggatcgagac aaaggtcgtc tctgtcagcc ggatcgtaga acatattggc ggcgccaaag
    12961 cccacttcac cgaccagacc gacgggatct atcaccagcc agccgcgact ggagaacatg
    13021 atgttttcat gatgcagatc gccatgtagc ccacgcagtt ccgaggcatt gctcatcatt
    13081 tgatcggcta taatcgccgc gtggacgtag tcagtttgac aacctgcgtt ttgatcatcg
    13141 cgcgcccgct gaaacaaagc tgcaaagcga tcccggatcg ggagaagggc agaaggcagg
    13201 ggttcctcag atgcggcata cagcttcgcc attagttccg ctgcaatttc ggtcgcctgg
    13261 tagtcgccgt gctcggcaac gatgtgagag agcattcgct ccccggcata ttcgagcaac
    13321 atcagattgt tctcacgacc gagcaaccgg actgctcccc tcccattgcg ccataccaga
    13381 tagtcggccc cgcgcagttc atcagcaatg tcttctatag gtttcaatcc cttgacgatt
    13441 gcaggagtcc cgtctggcaa tgaaactttc caaacgaggc tggaaaaggt gtccgcaatg
    13501 agaacaggtt gcgaaacgtg ccaatgagca ggaaaaacag gcggcatgaa catcaacccc
    13561 aagtcagagg gtccaatcgc agatagaagg caaggcgttc gcggtcgggg gcttcgatcc
    13621 ccaatacatt gaataggaca gcgaaggcgc gctctgcttc atctggcgct gcccagttct
    13681 cttcggcgtt agcaatcatg agtgccaaat cggcatagcg atctgctgtt ccgagccgcc
    13741 caaggtcgat cagacccgtg cattgaagag ttttagggtc caccatgaag ttcggcatgc
    13801 agggatcacc atggcaaaca accatatcgg tgcgctcttg gtcgagccgc accggtagct
    13861 ctcgttcgac acgagccaaa agatcgagct gcggcgtact cttgtcctcg tccggtaaga
    13921 agtcgggatt gacggcattg cgggacacca catcaacggc gcgtccgaac attcgcgaca
    13981 gcctgcgctc aaactgacat tgatcaaccg ataggctgtg aacagcgcca agttgctgcc
    14041 ccattgacgg ccacgctttg agcaaatccg ctccagacag atcagccgcc ggtactcccg
    14101 gaattgccgt tatcaccaag catgcaccct cctgttcctc ctgccagttg atgacctcgg
    14161 ggcaagccac acctcgacct ttgagccaaa tgaggcggtc acgctctcca gcgagctcac
    14221 cgcggcggga agcaggtgcg attttcgcga aggcatgccc gtcaccacgt cgaaaaacaa
    14281 aatcaccaga ttctccgcct ctgacaggca accagtcaga atgcgattca ccaaaaaaaa
    14341 tattagttcg attcaatgga ggttccttca gttttctgat gaagcgcgaa tatagagaaa
    14401 tatcccgaat gtgcagttaa cgaattcttg cggtttcttt cagcgccgcc aataccgcca
    14461 gcccgtcgcg caaggggcgc ggctcgtgtg tgcggatgaa gtcagctcca cctgcggcgg
    14521 cggcaagctc tgcagcgagt gtcgcggccc cgacatcccc cggaccacgg cctgtgagcg
    14581 cgcgcagaaa ggatttgcgc gaaacagaca gaagcaccgg caaatcgaag cgcagccgca
    14641 attcatcgaa ccgcgccagc accgagagcg aggtttcggg agcagccccc agaaaaaacc
    14701 ccatgccggg atcaaggaca aggcggttgc gtttgatacc ggcacccgtc agcgccgcga
    14761 tgcgcgcgtc aaagaacgcc gcaatgtgat ccatgatgtc gccagcgggt gcctcgcgcc
    14821 gatctgcctg cccgtcttgc accgaatgca taacgacgag tttggcagat gatttcgcca
    14881 attgcggata gaacgcagcg tctggaaaac cgcgaatatc attgagatag gccacaccac
    14941 gcgacaaggc ataggcttgc gtcgcgggtt gataactgtc gagcgagacg ggaatgccat
    15001 ctgccttgag cgcgtccagc accggcgcga tacgcgcgat ttctgtgtcg gacgaaacag
    15061 gcgcggcgtc gggattgctg gatgccggac cgaggtcgat cacatctgcc ccctcggcca
    15121 tcagcttacg cgcctgcgca atggctgcgt ctggcgccag ataccggcct ccatcggaga
    15181 aactgtccga ggttatgttg acgatgccga aaatgatgag cgatttattc atgggggctt
    15241 ctataataat aataatcgag catgagtctc atacggatgc tcgggtcgaa agggaatccc
    15301 caggcgagta acctgtttgc ggtgatccgt ttcatgatga tgtatctgta gcattttgga
    15361 aataaatata tcatctctca ataagtagat atatttatct tttttgcttc tttggtgctg
    15421 caagtcacca atacgaggga aacctgttac ggagcggttt aaccgtaatc aacagtgact
    15481 ggtgtcatgt tcggaagatt aattgatagt aatctacaaa ggatcttctt gagatccttt
    15541 ttttctgcgc gtaatctgct gcctgtaaac gaaaaaaccg cctggggagg cggtttagtc
    15601 gaaggttaag tcagttgggg actgcttaac cgggtaactg gctttagtgg agcacagata
    15661 ccaaatgctg tccttccagt gtagccgcta taaggcttca acttcaagag ttctgcgtat
    15721 ctaaatccac tatccagtta ccaatggctg ctgccagtgg cgttaagtcg tgtcttaccg
    15781 ggttggactc aagacgatag ttaccggata aggcgcagcg gtcgggctga acggggggtt
    15841 cgtgcacaca gcccagcttg gagcgaacga cctacaccga actgagatac caacagcgtg
    15901 agctatgaga aagcgccacg cttcccgaag ggagaaaggc ggacaggtat ccggtaagcg
    15961 gcagggtcgg aacaggagag cgcacgaggg agccaccagg gggaaacgcc tggtatcttt
    16021 aagtcctgtc gggtttcgcc acctctgact tgagcgtcga tttttgtgat gctcgtcagg
    16081 ggggcggagc ctatggaaaa acgccagctg cgtggccttt tccgggttct tgttttttgc
    16141 tcacatgttt cttttggtgt tatcccctga ttctgtggat aacagcattt cgtttttgag
    16201 tgagtagata ccgctcgccg cagtcgaacg accgagcgta gcgagtcagt gagcgaggaa
    16261 gcggaaatat ctcctgtatc gcatatcctg ctgacgcgct ggtgccgcct tttttctcct
    16321 gctacatgaa gcacttcact gattttcgca atcgtggcaa catagtaagc cagtatacac
    16381 tccgctatcg ctacgtgact gggtcagggc ttcgccccga cacccgctaa caacctctca
    16441 gctactggat atcaccccat gccatctgaa tatgatgaac aactggattc gactgatacg
    16501 cagcttcccg gcgaatatga cctttttgat ttaatggcgc aggttactga agagaacctg
    16561 catgcccctg tggattttgg gtcgcctgtc ggccgggaag cgttatagct ttttcgcttg
    16621 cccgcgtacg tggtaatact ccggtattac cttttatttc tttattttca tgtaattaca
    16681 gtggattttt aatacccggg tattactcgt gaaaacgaaa tattcctttt ttttctttta
    16741 attcatgcag ttgcgatgaa aatcgcggct gcgttaggtg tatgaccatt ttgaggttga
    16801 aaaataatca acc
//
