LOCUS       CP100008               27742 bp    DNA     circular BCT 21-JUL-2022
DEFINITION  Escherichia coli strain EC737A1 plasmid p737A1-27K-cfr, complete
            sequence.
ACCESSION   CP100008
VERSION     CP100008.1
DBLINK      BioProject: PRJNA827955
            BioSample: SAMN27625662
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27742)
  AUTHORS   Ni,J., Lin,J., Pan,D., Yang,H. and TANG,B.
  TITLE     cfr-harboring E. coli strains isolated from food animals
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27742)
  AUTHORS   Tang,B., Chang,J., Wu,J., Yang,H., Lin,J., Guan,C., Jiang,H.,
            Chen,H. and Li,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Institute of Agro-product Safety and
            Nutrition, Zhejiang Academy of Agricultural Sciences, 198 Shiqiao
            Road, Hangzhou, Zhejiang 310021, China
REFERENCE   3  (bases 1 to 27742)
  AUTHORS   Ni,J., Lin,J., Pan,D., Yang,H. and TANG,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUN-2022) Institute of Agro-product Safety and
            Nutrition, Zhejiang Academy of Agricultural Sciences, 198 Shiqiao
            Road, Hangzhou, Zhejiang 310021, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. JAN-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2022 21:57:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.1
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 4,772
            CDSs (total)                      :: 4,653
            Genes (coding)                    :: 4,434
            CDSs (with protein)               :: 4,434
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 219
            CDSs (without protein)            :: 219
            Pseudo Genes (ambiguous residues) :: 0 of 219
            Pseudo Genes (frameshifted)       :: 73 of 219
            Pseudo Genes (incomplete)         :: 138 of 219
            Pseudo Genes (internal stop)      :: 50 of 219
            Pseudo Genes (multiple problems)  :: 37 of 219
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27742
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EC737A1"
                     /isolation_source="gut"
                     /db_xref="taxon:562"
                     /plasmid="p737A1-27K-cfr"
                     /geo_loc_name="China:Zhejiang"
                     /collection_date="2020-10"
     gene            52..717
                     /locus_tag="MZH82_23585"
     CDS             52..717
                     /locus_tag="MZH82_23585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA protein"
                     /protein_id="UTU21843.1"
                     /translation="MAKQSPCYNVVSRKRRRFLNRWIKSLTTVAGRIKIKNELRRRIRH
                     NRYWVNEANKFGIEALCELMLAILDDLDLRSWETRHNLETLAERAGLVTRSDAGHKSIS
                     RASRGCDRLVWLNAIITEKAPFNPYDARCACKHIEVTEDFFAILGIPLKLVYRERARLL
                     KADPDEVIYSGDARLIAIRVQNWTRKAAAGLARMKAKRDAARQRKKEYYAHSPTPIPA"
                     /name="RepA protein"
     gene            1674..1946
                     /locus_tag="MZH82_23590"
     CDS             1674..1946
                     /locus_tag="MZH82_23590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21844.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTNQEGT
                     KFLSTLQEITTELDALIDAVESHSPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            2020..2319
                     /locus_tag="MZH82_23595"
     CDS             2020..2319
                     /locus_tag="MZH82_23595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21845.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGKKYIVVFTDNNK
                     IRDYKNGVIEELGEIMQEDIELIEYYAKKYEKYFDNLKIGEEPLNLKEYIECMQ"
                     /name="hypothetical protein"
     gene            2690..3223
                     /locus_tag="MZH82_23600"
     CDS             2690..3223
                     /locus_tag="MZH82_23600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="UTU21846.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKDAFKKAALKYHPDRNPVGAEMMK
                     AANSAFDFLMANLDKINQYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEYKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="DnaJ domain-containing protein"
     gene            3351..3893
                     /locus_tag="MZH82_23605"
     CDS             3351..3893
                     /locus_tag="MZH82_23605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21847.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTEFRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANAPDEIELL
                     RGHESALQEKQDKVRIIKGMLSQLLSISPWYGALTGFNADNGLAGKILQNGDDYEMVIR
                     GLNVEQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            3930..4187
                     /locus_tag="MZH82_23610"
     CDS             3930..4187
                     /locus_tag="MZH82_23610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21848.1"
                     /translation="MKTDNVFFKSKGSYSYVITVDMDNQVYMVRKYVKTYVKSCDKEQV
                     KGKKTVKKLVLDTNLTLPELLSLDNGILADLFTRGNNNAN"
                     /name="hypothetical protein"
     gene            4177..4416
                     /locus_tag="MZH82_23615"
     CDS             4177..4416
                     /locus_tag="MZH82_23615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system MqsA family
                     antitoxin"
                     /protein_id="UTU21849.1"
                     /translation="MQTKPTPADVKEARVSAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTVGILNN"
                     /name="type II toxin-antitoxin system MqsA family
                     antitoxin"
     gene            complement(4649..5353)
                     /locus_tag="MZH82_23620"
     CDS             complement(4649..5353)
                     /locus_tag="MZH82_23620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UTU21850.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            5536..6585
                     /gene="cfr"
                     /locus_tag="MZH82_23625"
     ARG             5537..6582
                     /name="cfr"
                     /gene="cfr"
                     /gene_name="23S rRNA (adenine(2503)-C(8))-methyltransferase
                     Cfr"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/LINCOSAMIDE/OXAZOLIDINONE/PLEUROMUTIL
                     IN/STREPTOGRAMIN"
                     /identity="99.71"
                     /coverage="100.0"
     gene            complement(6671..7375)
                     /locus_tag="MZH82_23630"
     CDS             complement(6671..7375)
                     /locus_tag="MZH82_23630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_function:
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UTU21852.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            7656..7940
                     /locus_tag="MZH82_23635"
     CDS             7656..7940
                     /locus_tag="MZH82_23635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21853.1"
                     /translation="MAKPKSEIDAIRALTEVTIKGFEQIVQALDDTREAQGKVARATYN
                     GLTSSGKSRYVASLVKEVGSQAEVSRMLNITPGRVSQLMKSEKNRKNGK"
                     /name="hypothetical protein"
     gene            complement(7974..8273)
                     /locus_tag="MZH82_23640"
     CDS             complement(7974..8273)
                     /locus_tag="MZH82_23640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="UTU21854.1"
                     /translation="MRTLEEVIASRSPESQARIKEMADEMILEVGLQMMREELQLSQKQ
                     VAEAMGISQPAVTKLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFHV"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(8273..8620)
                     /locus_tag="MZH82_23645"
     CDS             complement(8273..8620)
                     /locus_tag="MZH82_23645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="UTU21855.1"
                     /translation="MWTVLFSQRFDDWLNEQEDALQEKVLADLKNLQVYGPELPRPYAD
                     TVKGSRYKNMKELRVQFSGRPIRAFYAFDPIRRAIVLCAGDKSNDKRFYKKLVRIAEDE
                     FAAHLNTLESK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            8985..9632
                     /locus_tag="MZH82_23650"
     CDS             8985..9632
                     /locus_tag="MZH82_23650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UTU21856.1"
                     /translation="MTVAIALVNGKGGVKKSSMSRAIATEYTKADWKVLGLDMDVDQGS
                     FLDWGQRRLRYKVEPPVTIQGCGTVSQAKKHIESGIWDLVVIDSAAYATKSLLSLAEIV
                     DLLVLPSGFSVDDLRTTVTTVNALRNKGYSTNKMAVVFVGVSESESEYRTALEYLKPCG
                     VQVINGAIPFMTSFSQAQDKGLALTESPFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     gene            9672..9905
                     /locus_tag="MZH82_23655"
     CDS             9672..9905
                     /locus_tag="MZH82_23655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21857.1"
                     /translation="MANVPPKPRNTKGEPPSLEDTQYGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(10175..10480)
                     /locus_tag="MZH82_23660"
                     /pseudo=""
     CDS             complement(10175..10480)
                     /locus_tag="MZH82_23660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(10490..10954)
                     /locus_tag="MZH82_23665"
     CDS             complement(10490..10954)
                     /locus_tag="MZH82_23665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="UTU21858.1"
                     /translation="MNILIIFALCILSSSPYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYERYNTDNDLATLQQEARSQKRGLWADPNPVPPWEWRHK"
                     /name="thermonuclease family protein"
     gene            complement(10958..11692)
                     /locus_tag="MZH82_23670"
     CDS             complement(10958..11692)
                     /locus_tag="MZH82_23670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="UTU21859.1"
                     /translation="MLIHDFHERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RSPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGIIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDEKNREMFIFRTIDELEQ"
                     /name="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
     gene            complement(11704..13431)
                     /locus_tag="MZH82_23675"
     CDS             complement(11704..13431)
                     /locus_tag="MZH82_23675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_component:
                     GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="UTU21860.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDMPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(14241..14546)
                     /locus_tag="MZH82_23680"
     CDS             complement(14241..14546)
                     /locus_tag="MZH82_23680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dpoa decarboxylase"
                     /protein_id="UTU21824.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     RLMRGVIEHTAKLKISDANKLISYAASQGYEITEDRYNAAIKAEDECLAEITRAQV"
                     /name="dpoa decarboxylase"
     gene            complement(14574..14789)
                     /locus_tag="MZH82_23685"
     CDS             complement(14574..14789)
                     /locus_tag="MZH82_23685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21825.1"
                     /translation="MDTDKNMVFYLTNSDLVYSYAHKIVHSIPSGMKGKFITSIGETIE
                     DLKKRHPDITLITESEALALQSERKN"
                     /name="hypothetical protein"
     gene            complement(14792..15091)
                     /locus_tag="MZH82_23690"
     CDS             complement(14792..15091)
                     /locus_tag="MZH82_23690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="UTU21826.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGSEC
                     RSAEKAFFNIIKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(15121..15519)
                     /locus_tag="MZH82_23695"
     CDS             complement(15121..15519)
                     /locus_tag="MZH82_23695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="UTU21827.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNEKLPEWNPN
                     SLIIKSPVINDKWTLSISSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFIAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(15516..16541)
                     /gene="virB11"
                     /locus_tag="MZH82_23700"
     CDS             complement(15516..16541)
                     /gene="virB11"
                     /locus_tag="MZH82_23700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_component:
                     GO:0043684 - type IV secretion system complex [Evidence
                     IEA]; GO_process: GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="UTU21828.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYNSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNIRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            complement(16554..16721)
                     /locus_tag="MZH82_23705"
     CDS             complement(16554..16721)
                     /locus_tag="MZH82_23705"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21829.1"
                     /translation="MNCKDKEIWLHMLAAGHMGVLAGNPNEAAAQDAYQRLIKSKTTLA
                     VYSSAPPESR"
                     /name="hypothetical protein"
     gene            complement(16705..17970)
                     /locus_tag="MZH82_23710"
     CDS             complement(16705..17970)
                     /locus_tag="MZH82_23710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="UTU21830.1"
                     /translation="MTDENKSPSTEEEKPVTTSDQDDIATLEREARAKREAELQASQDD
                     EKENSLQPAVNKLKKRQKGKATAFLAICAVALIGLTWGGNWVYQNFLKQEDGEKTKEVT
                     PPKKTNDYRKRTDLGMATNEPENSTDGEQAVSQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGKIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRMKNELQR"
                     /name="TrbI/VirB10 family protein"
     gene            complement(18012..18917)
                     /gene="virB9"
                     /locus_tag="MZH82_23715"
     CDS             complement(18012..18917)
                     /gene="virB9"
                     /locus_tag="MZH82_23715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="UTU21831.1"
                     /translation="MRKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQAQIQKALRTAQTPRNWDYTKYPGKDSYSIEPDFAYDDGRFTFIGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQDITPRLVLRSGDAVVGLKNNGFGKVH
                     AADNSTVSNKVERVEKTDNT"
                     /name="virB9"
     gene            complement(18917..19600)
                     /locus_tag="MZH82_23720"
     CDS             complement(18917..19600)
                     /locus_tag="MZH82_23720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="UTU21832.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLIAILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            complement(19593..19736)
                     /locus_tag="MZH82_23725"
     CDS             complement(19593..19736)
                     /locus_tag="MZH82_23725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21833.1"
                     /translation="MKRLIALALLCVLSGCAQKSKPLPPAFSGQGSPVNTPQIIAELTT
                     HD"
                     /name="hypothetical protein"
     gene            complement(19786..20856)
                     /locus_tag="MZH82_23730"
     CDS             complement(19786..20856)
                     /locus_tag="MZH82_23730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="UTU21834.1"
                     /translation="MSGGVFVGVEKHLIGGITDATQGLMMSYSSMMMGLAGTSATIYII
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGLKEGFSSSSSI
                     WQLLDTLWHNAKVLGKTLHDLDDSEFIKDEGTIAELFVWGGVFVLMIITAFVSMVAEVM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAGILTILLSSLSLRIVISYLNSRLALA
                     SSGANQANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     STPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            complement(20865..21092)
                     /locus_tag="MZH82_23735"
     CDS             complement(20865..21092)
                     /locus_tag="MZH82_23735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="UTU21835.1"
                     /translation="MRLLTITLLSLSAFLINGCEEEAKTTKWYRTHPDELKAVYEKCQK
                     TGSASENCKHANEAHWQIQQLNAPTVDLNQ"
                     /name="EexN family lipoprotein"
     gene            complement(21102..21809)
                     /locus_tag="MZH82_23740"
     CDS             complement(21102..21809)
                     /locus_tag="MZH82_23740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="UTU21836.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLAEERRKKWN
                     QQQLNAPTLDLNS"
                     /name="type IV secretion system protein"
     gene            complement(21824..24568)
                     /locus_tag="MZH82_23745"
     CDS             complement(21824..24568)
                     /locus_tag="MZH82_23745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="UTU21837.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLFLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLITHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLVADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDARTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(24581..24877)
                     /locus_tag="MZH82_23750"
     CDS             complement(24581..24877)
                     /locus_tag="MZH82_23750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="UTU21838.1"
                     /translation="MFNKLKTICSRASAYILAPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            complement(24881..25585)
                     /locus_tag="MZH82_23755"
     CDS             complement(24881..25585)
                     /locus_tag="MZH82_23755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="UTU21839.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTKDDIATQSAILNATPVEAPARPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(25601..25807)
                     /locus_tag="MZH82_23760"
     CDS             complement(25601..25807)
                     /locus_tag="MZH82_23760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21840.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNEKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     gene            complement(25808..26020)
                     /locus_tag="MZH82_23765"
     CDS             complement(25808..26020)
                     /locus_tag="MZH82_23765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UTU21841.1"
                     /translation="MPNPIGQAKSTAVIYIGKKRYETLAKHARDISYVAEVNIRPSAFL
                     QYMIDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            complement(26097..26546)
                     /locus_tag="MZH82_23770"
     CDS             complement(26097..26546)
                     /locus_tag="MZH82_23770"
                     /inference="COORDINATES: protein motif:HMM:NF014417.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator NusG"
                     /protein_id="UTU21842.1"
                     /translation="MNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIKFTPRKDCNAV
                     RKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKVVIAIKCAKIL
                     ALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcriptional antiterminator NusG"
     gene            26799..27167
                     /locus_tag="MZH82_23775"
     CDS             26799..27167
                     /locus_tag="MZH82_23775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="UTU21861.1"
                     /translation="MVPKRLKEAREAAGLSQEKLSELVGIEGTSTRSRMSNYEAGRFTP
                     PFKFICRVADVLGYPEYYFYIVNDVTAKKLLQMYKGEKNSIENIELEASRMADQLDDAR
                     KLVSQLSDCVRELKRSLG"
                     /name="helix-turn-helix domain-containing protein"
     ARG             5537..6585
                     /name="cfrA"
                     /gene="cfrA"
                     /gene_name="Cfr 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic; streptogramin
                     antibiotic; streptogramin A antibiotic; oxazolidinone
                     antibiotic; phenicol antibiotic; pleuromutilin antibiotic"
                     /identity="99.71"
                     /coverage="100.0"
     Typing          complement(10962..11692)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="7.77e-164"
     Typing          complement(18921..19600)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.903"
                     /coverage="100.0"
                     /evalue="3.86e-119"
     Typing          complement(21828..24568)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.527"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtggtggctg aaaagaacaa ctccttaatc ccccgcatat cgccgtcagg tgtggcaaaa
       61 caaagtccat gctataacgt tgtgtcgcgt aagcgacgcc gttttctcaa tcgctggatt
      121 aaatcgctga cgacggtcgc agggcgtatc aaaatcaaaa acgaactccg tcgccgtatc
      181 cggcataacc gctattgggt taatgaggct aacaagtttg gcatagaggc tctttgcgaa
      241 ttgatgttag ctattctgga cgatctcgat ttacgctcgt gggaaaccag gcataacctt
      301 gaaacgcttg ccgaacgtgc cggactggtt acacgcagcg atgcgggaca taaatccatt
      361 tctcgcgcca gtcgtggttg tgatcgcctg gtttggttga atgccatcat tacagagaag
      421 gctccgttta acccgtatga tgcacggtgt gcctgtaaac acattgaagt aaccgaggat
      481 ttctttgcca tccttggcat tccgttaaaa ctggtttatc gggaacgagc caggctgtta
      541 aaggcagatc ctgatgaagt gatttactcc ggtgatgcca gacttatagc tatcagagtc
      601 cagaactgga cgcggaaagc ggcagccgga ttagccagga tgaaagcaaa acgcgacgca
      661 gctcgacaac gcaaaaaaga atattacgca cattcaccta cccccattcc ggcctgatgc
      721 tggctactta ccgccttatg ggcggtatat cgtcacgtcc ataataaatt tctgtacaaa
      781 aaatagtctt agcgtgagat attttcgttt tccaagcggc tccctgctca ggaaagagca
      841 gccataggtt atggccagag ggtaaacgat gtacagcttg tggataatca taagtgaagt
      901 gcaaacgata tgacgcaatt actcttttgc ttctctttta gttacttacg tactaaaaga
      961 gaagcaaaaa gaaaaacatt actgttatcc cctttaacaa gtggataact gaaaagcatc
     1021 ggcgcaagcg cctcaaaggt agcacccctc gcaagcatcg gggcattaga gacaccatat
     1081 ccgatcatta aaaacgaaca atcattcacc tatcatcgct gtaacatcga cggtctacga
     1141 ccacctaccg cctaagtagc tgtaggttcc gtgcaatttt ggcttagcag ggggctgacg
     1201 cggttcctgg cgacatgaac gtctttgatt aggggtatcg gcgcgcctta gcatttgtga
     1261 ttctatggaa ctgtatttcg cgccttacat gccgctaacg cggcatcttc ccaccatcga
     1321 gcataactta actaactgct aacaatatga tcgagaaaga tcacaaaaag gttcctgttg
     1381 ggggtctgtt tggaaatcgg aaatttcggc gtttccggtg tacaacccta gggaggtaga
     1441 tccgctcgcc gcagccccag cgaccgaacg tagtgagcga gtgggcgagg aagcggaata
     1501 gtgcccttgc tgaattgagc acatacgcga aggaattaaa ggtgagtggt ggaaaatttt
     1561 tcagttcgaa tagtgaaaaa tagttgcaat acctgcatac gcaggtataa taaaatcatc
     1621 gaaagggaaa taggttccct ttccacttag ccccacaggg gcgggagatt aaaatgagtg
     1681 catttatttt tagaaccaca tttaaagcaa ctggcgatca gcaaaaagac gctattaccc
     1741 aaattgaagt tatgcaggaa caagcagtaa aagcctttgt ttcttggatg accaaccagg
     1801 agggtacaaa atttttaagc actttgcagg aaatcacaac agaacttgac gcactgattg
     1861 atgcggtaga gtcccattcc cctgttttca gaaagaaagc gactgaactg gaagcgcttt
     1921 tagcccatta caaaacgttg ctgtaagtcc tcaacggggc aattgccccg ttatatggct
     1981 ctttatttaa tccaaatcta aagcaagtgg agtttaaaaa tggctcgctt accttatatt
     2041 gaatcaacca cgcaacagat ttttattttt aatactttga cactttgtac tattggatta
     2101 attcatatag agactggtaa aaaatatatt gtagtattta cagataacaa taagattcga
     2161 gattataaaa atggtgtaat agaagaatta ggggaaatta tgcaagaaga tattgaactg
     2221 attgagtatt atgctaaaaa atatgaaaag tattttgata atttaaaaat aggtgaggag
     2281 cctttgaatc ttaaagaata tatagaatgt atgcaatagc catatattct ataaaggtgt
     2341 gatcaggttg gtcgagcaac ctgatcactc tatcgacact caaaacaata gagaggtgtt
     2401 caaatgtcaa caggtcagat cgtacaactt gcggattcac ttgtcaaagg atgggaaacg
     2461 agaatcccag caatgaaatt tacggattgg gatcaattca ggtggtggtt aaattattta
     2521 cagggatatg aaatgtttta agtaatgttg atgtcctgac agtaattata aaatttttca
     2581 aaaagagagc taaaaaactt gcaatacctg caattgaagg tataattaaa ccatcgagag
     2641 ggaaatggtt tccctctcat cttagcccca caggggcggg agttacaaaa tgaatatcca
     2701 agaagcatta aatatttttg gcttgtctgg tcagttgact gaaaaagaca tcaaagatgc
     2761 ctttaagaaa gctgcattaa aatatcaccc agaccgtaat ccggtaggtg ctgaaatgat
     2821 gaaggcggct aattcagcat tcgatttttt aatggcgaat cttgataaga ttaatcagta
     2881 ccaaagtcct gaacaaagtg caatatataa ctatggtgat gaactagaaa atgttttaaa
     2941 ggctctttac ggtttgtctg gtttagttta tgaggttatt ggtaactgga tctggattag
     3001 tggaaatact atcgagcaca aagaagcatt aaaagaaata gggtgtaaat gggcggcaaa
     3061 gaaaaaacaa tggttttatc gtccagaaga atataaaagt tactggaacc gtgaagagca
     3121 cacgatagag gaaatccgcg caaaatatgg cacaagcgga aaattccagg ccggaggatg
     3181 gcaacaagtt gaaggcaggg caagagttga agccagagca taacgaaacg ggggcgtaag
     3241 ccccctatat cctcgccagc aatccttttc gggcatcgaa cccgaaaagg attgagtagc
     3301 tgacactctg cgattgctgg ctacgttagc gcagtaaagg atgtgaaagc atgacaacat
     3361 tttcagaaaa atatcagcct gtctttgaag ttgtatgccg tattcttggg aacggctggc
     3421 gtgttaacaa actggataat tatcagcatc gtattaaact gacttctaca gaatttcgta
     3481 aatactccat cattattcgt ctggagcgtg aaagattttt tatagttggt agcgttgata
     3541 gtcttgtatg gcacggtaat ccttccgtct gtactgtatc tcttacgcgc aatcctgttg
     3601 gtattgctaa tgatatatct cggaaaatcc ttgctaatgc accggatgaa attgaattgc
     3661 tcagggggca tgagagcgca ttacaggaaa aacaagataa agtgcgaata atcaaaggga
     3721 tgttatcaca gttgctttct atatctccct ggtatggggc attaacggga tttaatgcgg
     3781 ataatggact tgcaggaaaa atactacaaa atggtgatga ttatgaaatg gttatcagag
     3841 ggcttaatgt tgagcaactt atcaaagtgg caggttttat aaaaaaacta taacaaagtg
     3901 ttgatgtgaa tttttatatg ggattgttta tgaaaactga taatgttttc tttaaaagta
     3961 agggtagtta ctcttatgtt attacagtag atatggataa tcaggtgtat atggtcagaa
     4021 agtatgttaa gacatatgtg aaatcttgtg ataaagagca agttaaaggg aaaaagacag
     4081 ttaaaaaatt ggtgcttgat acgaatctta cattgccaga attattgagt cttgataatg
     4141 gtattctggc tgatttattt acaagaggta ataacaatgc aaactaaacc aactccggca
     4201 gatgttaaag aagcgagagt ttccgcaggt ttaacgctta aggaagccgc cgaaattttc
     4261 ggctatcagt taaatacctg gcaaatgaaa gaaagcgcag gtaaagctac aaggtcttta
     4321 tcagtaggtg aatataacta cttattgttg ttggctggaa aacaccctga atatgttctt
     4381 tgtaaaaggg atacagtggg tattttaaat aattaaggat aatacaatta attcgccgaa
     4441 aatgaacttt tcgcccattt tcggctttca ctcctaaaaa gctgcaatta ttcacgcatc
     4501 atttgcagtc ctgtttccag aatcatctca ttagccatgg ctttggtgac ggaattttct
     4561 gggtttccgg tttagaaccc ccttaggaaa tttttcggca ctgttgcaaa gttagcgatg
     4621 aggcagcctt ttgtcttatt caaaggcctt acatttcaaa aactctgctt accaggcgca
     4681 tttcgcccag gggatcacca taataaaatg ctgaggcctg gcctttgcgt agtgcacgca
     4741 tcacctcaat acctttgatg gtggcgtaag ccgtcttcat ggatttaaat cccagcgtgg
     4801 cgttgattat ccgtttcagt ttgccatgat cgcattcaat cacgttgttc cggtacttaa
     4861 tctgtcggtg ttcaacgtca gacgggcacc ggccttcgcg tttgagcaga gcaagcgcgc
     4921 gaccataggc gggcgcttta tccgtgttga tgaatcgcgg gatctgccac ttcttcacgt
     4981 tgttgaggat tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat
     5041 aaaaatcgac agtgcggccc cggctgtcga cggcccggta cagatacgcc cagcggccat
     5101 tgaccttcac gtaggtttca tccatgtgcc acgggcaaag atcggaaggg ttacgccagt
     5161 accagcgcag ccgtttttcc atttcaggcg cataacgctg aacccagcgg taaatcgtgg
     5221 agtgatcgac attcactccg cgttcagcca gcatctcctg cagctcacgg taactgatgc
     5281 cgtatttgca gtaccagcgt acggcccaca gaatgatgtc acgctgaaaa tgccggcctt
     5341 tgaatgggtt catgtgcagc tccatcagca aaaggggatg ataagtttat caccaccgac
     5401 tatttgcaac agtgccaaaa aaagttggta atgggataaa taaaaaagaa aaaaccaaat
     5461 tcaaaaatta tatggagatc tgtataataa agaataatta ttaatctgta gacaaattgt
     5521 gaaaggatga aagaaatgaa ttttaataat aaaacaaagt atggtaaaat acaggaattt
     5581 ttaagaagta ataatgagcc tgattataga ataaaacaaa taaccaatgc gatttttaaa
     5641 caaagaatta gtcgatttga ggatatgaag gttcttccaa aattacttag ggaggattta
     5701 ataaataatt ttggagaaac agttttgaat atcaagctct tagcagagca aaattcagag
     5761 caagttacga aagtgctttt tgaagtatca aagaatgaga gagtagaaac ggtaaacatg
     5821 aagtataaag caggttggga gtcattttgt atatcatcac aatgcggatg taattttggg
     5881 tgtaaatttt gtgctacagg cgacattgga ttgaaaaaaa acctaactgt agatgagata
     5941 acagatcaag ttttatactt ccatttatta ggtcatcaaa ttgatagcat ttcttttatg
     6001 ggaatgggtg aagctctagc caaccgtaaa gtatttgatg ctcttgattc gtttacggat
     6061 cctaatttat ttgcattaag tcctcgtaga ctttctatat caacgattgg tattatacct
     6121 agtatcaaaa aaataaccca ggaatatcct caagtaaatc ttacattttc attacactca
     6181 ccttatagtg aggaacgcag caaattgatg ccaataaatg atagataccc aatagatgag
     6241 gtaatgaata tactcgatga acatataaga ttaacttcaa ggaaagtata tatagcttat
     6301 atcatgttgc ctggtgtaaa tgattctctt gagcatgcaa acgaagttgt tagccttctt
     6361 aaaagtcgct ataaatcagg gaagttatat catgtaaatt tgatacgata caatcctaca
     6421 ataagtgcac ctgagatgta tggagaagca aacgaagggc aggtagaagc cttttacaaa
     6481 gttttgaagt ctgctggtat ccatgtcaca attagaagtc aatttgggat tgatattgac
     6541 gctgcttgtg gtcaattata tggtaattat caaaatagcc aatagtattg aacaaggtat
     6601 atagctgata taataagggg cactgttgca aagttagcga tgaggcagcc ttttgtctta
     6661 ttcaaaggcc ttacatttca aaaactctgc ttaccaggcg catttcgccc aggggatcac
     6721 cataataaaa tgctgaggcc tggcctttgc gtagtgcacg catcacctca atacctttga
     6781 tggtggcgta agccgtcttc atggatttaa atcccagcgt ggcgttgatt atccgtttca
     6841 gtttgccatg atcgcattca atcacgttgt tccggtactt aatctgtcgg tgttcaacgt
     6901 cagacgggca ccggccttcg cgtttgagca gagcaagcgc gcgaccatag gcgggcgctt
     6961 tatccgtgtt gatgaatcgc gggatctgcc acttcttcac gttgttgagg attttaccca
     7021 gaaaccggta tgcagctttg ctgttacgac gggaggagag ataaaaatcg acagtgcggc
     7081 cccggctgtc gacggcccgg tacagatacg cccagcggcc attgaccttc acgtaggttt
     7141 catccatgtg ccacgggcaa agatcggaag ggttacgcca gtaccagcgc agccgttttt
     7201 ccatttcagg cgcataacgc tgaacccagc ggtaaatcgt ggagtgatcg acattcactc
     7261 cgcgttcagc cagcatctcc tgcagctcac ggtaactgat gccgtatttg cagtaccagc
     7321 gtacggccca cagaatgatg tcacgctgaa aatgccggcc tttgaatggg ttcatgtgca
     7381 gctccatcag caaaagggga tgataagttt atcaccaccg actatttgca acagtgccaa
     7441 tttttcccac ctgtaaagca ctttttatat aaatctataa ttatataaaa ataatcgatg
     7501 tttttttgaa cgctttttac taaacatatt tgtttagtgc atcatggtgt attttataga
     7561 tcttgaaaag acaatgacag tagtgatagc atctaagaca gccgagacgt acagcccaac
     7621 aacttaataa aatataaaca catgagggtc ataatatggc aaagccaaaa tctgaaattg
     7681 atgctattcg agcattaaca gaagtaacaa taaaaggttt tgagcagatt gttcaggcat
     7741 tagatgatac gagagaagct cagggaaaag tcgcacgagc aacatataat ggattaacct
     7801 cctcaggaaa atctcgctat gttgcatcgc tagtgaagga agtaggatca caagctgaag
     7861 taagccgcat gttaaatatc acaccagggc gcgttagcca gcttatgaaa tccgaaaaaa
     7921 accgcaagaa tggtaagtaa ataagtaagg ccccaatggg gccttacatt atgctagaca
     7981 tggaacgcta ctcgctttcc tgtaggaagc tcaacatcca ggcttaattt gcctcccata
     8041 gcttcaacgt aacgctttaa tgtcgccagc tttaaatcat ttccgcgctg ctccagcttt
     8101 gttactgctg gctgactaat acccatcgcc tcagcaacct gtttttgtga taactggagt
     8161 tcttcacgca tcatctgcaa gccgacctca agaatcatct catctgccat ttctttaatt
     8221 cgcgcctggc tttccggtga acggctggca atcacctctt ctaatgttct cattacttgc
     8281 tctccagtgt gttcagatgt gctgcaaact catcctcagc tatacgcacc agttttttat
     8341 aaaaccgctt atcgttactt ttgtctcctg cacaaagaac gatagcccgg cgaatcggat
     8401 cgaacgcata aaaggctctt atcggacggc cagaaaactg aacgcgaagc tctttcatat
     8461 ttttgtaccg agaacctttt acggtatcgg catatggcct gggtaactca ggtccgtaaa
     8521 cctgtagatt tttcaaatca gccaaaacct tttcctgaag agcgtcttct tgctcattta
     8581 gccagtcgtc aaatcgctgg ctaaaaagta ccgtccacat gatcaatcct ataacctgta
     8641 gtttatatca ctaactatat aacccgtagg ttataatttc aagaaaaacg gggctattta
     8701 acataatgga cgttatcggc accatcggat caccgttcgt tgtcggatct gcaaaatccg
     8761 ctcaaaagat catgttttct tggcgttttc caccgttttt tgtgttgcgc atttgttaat
     8821 aaaacatcgt tttttgtttt ggctgaattt tgttgtgaaa gccttgtatt cacaagttat
     8881 ctcttcactt gccgcctgta gttcaaatag ttgttgcaat tcttggcacc aatacggata
     8941 ctataattat atttttctat aaaaatattt ttataggggg tcgtatgacg gtagctattg
     9001 cgctggttaa cggtaaaggc ggggtgaaaa agtcctcaat gagcagggct attgccacag
     9061 agtacacaaa ggcagactgg aaggtattag ggcttgatat ggatgttgat caggggtcat
     9121 tcctggattg gggacagcgg cgattgagat ataaagttga accacctgtc actattcagg
     9181 gatgcggaac ggtatcacag gctaaaaaac atattgaatc agggatatgg gatttagtcg
     9241 ttatcgatag tgctgcttat gcaactaaat cgctgttgag cctggcagaa attgttgatt
     9301 tgctcgtgtt accgtcaggt tttagtgtgg acgatttgag aacgacggtt acaaccgtga
     9361 atgcattgcg taacaaggga tactcaacaa ataagatggc tgtagttttt gtcggagtca
     9421 gtgaaagcga aagtgagtat cgtaccgcgc ttgaatatct taaaccgtgt ggtgtccagg
     9481 ttatcaatgg cgcaatacct tttatgacct cgttcagcca ggcacaggat aaaggactgg
     9541 cattgacgga atcccctttt ccaggtccac ggcagaaagc tgatgaagtt gtccagggag
     9601 ttattgactt gctgactaaa ctctcacagt gatatataat tctataatta tatttttata
     9661 gaggtgataa gatggctaat gtaccaccaa aaccgcgtaa caccaaaggc gagccgccaa
     9721 gtctggagga tacacaatac ggatttaatc cgacgcgtaa aaacgctgat gggagaaaag
     9781 ctcagcttaa cctttatgtg gatatggaag ttaaacggga gttccgctcg attgcagcgg
     9841 ctaatgatat gaagcacggg gagttgctgg aggcatacca ggaattctgg aaaaagcatc
     9901 attaaaatgt cataggggac gaactgtccc ctgatattaa cacttactta ccaacataat
     9961 gaatatggtc aatacgacaa gtatttttat cgtcatcatc gtctccatta tcatattctg
    10021 gaaacactat tagtaacgct tcgccgttgg tgcgtttcat aaaattgaac actaatctgc
    10081 ctacttcttc atttgtcata tagcgttcta ttggcaatgt ttcgtattga tccgcataga
    10141 gaatattcac actttcttct tctggttctg aaatctggcc aattgtgata tctgtcagac
    10201 ctgtatcagt gaaatttcct gattttatgt caaagtcgcc atctttgaat ttgtatgcat
    10261 cctgccatac agcgaaacaa gtgtggcagg tgatgggcag ttcgccttca gccagctttt
    10321 cacaattttg aaccagtact cgctcttggt tgtactgtaa gttatagcca cctgtacaaa
    10381 gcgtttcata cccatgagcg ccagttacga tatgtgtcgc aaccctttcc aagactttcc
    10441 cattcactaa taactgttca cgtgtggtaa ttgtttgcat gtcaatctcc tatttatgtc
    10501 gccattccca cggtggaacg ggattggggt cagcccataa acctcgtttt tgtgagcgag
    10561 cttcctgttg tagagttgct agatcgttat ctgtgttgta acgctcatac acccatgcag
    10621 cacccgattg caccataaag cggttagcct cactgccgcc tgttgtgaat acacgtccga
    10681 taatgcgacc gtaacggtca ttgtgtgaat atgtcaccct gacggattgt ccggcaatca
    10741 ggcttttaag ctggtcagtt gaccagcgtc cgtaagcctg tttcttttcc ggtgcatcaa
    10801 tattggccag acgaatcctc actggtgttt tattctgtaa aatttcgatg gtatcgccgt
    10861 caagtacacg aataactttt ccctgtatat ccgctgcatt ggcatatggt gaagacgaca
    10921 agatacatag tgcgaatatg attaatatat tcatcaacta ttgttccagt tcatcaattg
    10981 ttctaaaaat aaacatttct ctgtttttct catcaaaagg cacaggtgta ttattcctca
    11041 ttacagtttt gattgagtcg aatagtctga ttaatgattc tttacttttg gtgtcaggca
    11101 tgacgtacaa agcataatgc cagtttcctt tatctcttgc cgtaagatga ctgtttataa
    11161 tgcttatata acgagcacga gttttcattg ttcgttctgt ttcaatagcc atgattgcgc
    11221 cagttggttg ttttattatt ccatccgggc gatgggaaca gccggagtaa cgtgcgatga
    11281 aggctgcact atcaccgtta atccattcag tagcgccttt actttccaga gatattctca
    11341 ctcgctgatt taaaagacga tgttcaagag tccagtattt tagtttgctg ggttcaaaat
    11401 aactagggaa cgtaatgtca tcggctttta caaccattgc taatccttgc atagtaatac
    11461 cccaaacagt taattttctt tttgatgatg gtatttcatg tttgataata aaaccttctt
    11521 taagagcctt gtttagtaat ttatatactg ggcttctgct tttttttgtg aatcctaatt
    11581 ttcttttgat aatgtgaaag tctgaatagg tttcatcctt aaggaaattt aaaaggcaaa
    11641 gcatgttgtt agctgatatt ctttttcttt cgtgaaaatc atgaattaac atatagtaaa
    11701 acctcataaa ccactggaag gcatatcgtt gttattgtgt tgttctattt gttctgtctc
    11761 aaaagatagc aattcaatgg tttctttgtt tgctggtata tgagacattt tagttgcttt
    11821 tggtaaatct tttgatgtga acacaaatcc tactctttca ggtagattta aaaacatatt
    11881 actgtctaca taataacttt ctgcctgtct tatcatgcgg tcagtatcaa ctttttctgt
    11941 taatgataag tcggttctta ccttcctcat ttcatcgtca actaatatgg aaccagtcat
    12001 tttagctgcc cactctgctg tttctggatt ctggatttta tagattaact tgaattttgc
    12061 gttttcaata acagcaccaa ttacagaatc gccattaaga tcagaaggac aatctcttaa
    12121 atcatctatt gcctggaagg ccataaatat atgcacactt ttatctcgtg ctgtacctaa
    12181 tccttccatt gttgggcgtg aaatatgata tttcaactca tcaaggaaaa ttgcaacaac
    12241 acgtggtgtt gtgtttattc tgtctctggt ttcagctatt tgaatcaaac gcgtaagtat
    12301 catgcgttgt gcagaaataa ttttttgatt tcgggttgac ccaatgatat agcagcatcc
    12361 tccattatca aaaatctctt taagagaaaa accatttttt gcattgacgg aatttacaag
    12421 agcgatttct tctagttcac ctaaaaatgc tggggcatct tctcctattg attttacgtt
    12481 gtcatcgttg aataaatcat acagtgtcat tcctgtttta tgaattgcgg ctacatttct
    12541 ggctgcgcgg cgatcagcta tacgataaaa atctgcggcc tctccttttt ttgatagact
    12601 aaatcctgcg ttaaataatt cttctaattg ttcatgtgat atgtcagcca gtaagtcaag
    12661 ttgatggttg gttctgttta aattaattac aacaaatttc tttcctgctt ttttacatgc
    12721 ttctctaaga acatgcacag cccattcatc atcttttgga tcttcaacaa aaacagcctc
    12781 gcctaataga attgcctgat aaagcaaaac cgatgcggta atgcccttac ctgaacctgt
    12841 tgtacctatg attgctgcat gttgtttctg aaattctttt attgttatat attgcggttg
    12901 gtcgtctttg tctaagccaa tgaaaacccc ttttttcaaa tcaatgtaat ctagaggatt
    12961 gtattctatg ctgtctggca acaattcttt tactttgcga acatctgttc ttgtatttct
    13021 ctcaagtttg cttttcttta tcattctgtg tttcagactg tctatttcac ctgctaataa
    13081 tcgtctcgct gtcaaatgaa aagctaatcc ggctagtgta aagagaatag tgattatcca
    13141 taatggtatt ctaagtagtg tatttggatc gagaacgtca aagagataac tcagtccatg
    13201 aatactaagt ggtgacattg ttccaaatat gaaaaagaaa atggacacgc acgcaacaga
    13261 ttttaaccag aagggagcgt tttttctttc ctctcgtggt aggttgaata taaatggaag
    13321 tgttagtcct gccagtaatg acaatatgac agggctgttc tgtagccata acagaaatat
    13381 tgaaaaagca tcagcaatac catttagctt ttgcattaga tgtggattca tatttatttt
    13441 ccccattcat aaagtgaatc tatggggtac gacaatgggg tacagtaatg ggggatataa
    13501 tgtaccccat agctgtaccc cattattgta ccccaataaa agccaaaaac gttgtgatcg
    13561 cctaaggcga tcatgcccgt tatccgttct ttcagaatcc agccgataag ttatcgtctg
    13621 gctcctgaaa gcccgaataa cgggcaacgg cgtgtgccgt ttcggcctgg ctggaacgcc
    13681 agtccttcac gtcacatggg ggtaatggcc cgtctggacg ccggaccaaa acccccaagg
    13741 tcaaaggcgg cacaccgtcg cgcgctacgc gcgaccaccc cctttaagac gcgcgtttag
    13801 cctatttttt cttcgcaagc tcgaaaaaat tggaacgctg ctttaaaggg ggtggtcgcg
    13861 cctaatcggt aatatccccc gctggggcgg gaaatattac ctggcccgac ggtgtgcggg
    13921 gcaagccccc cacaaaaacc ggcacgtggg cgtgcctttt ttctcgctgg ggcggaaaaa
    13981 tttttgcggc tccccccggc ccgcttcaat tcgcttgggg cgaatgttcg cgggtgggcg
    14041 tggtgcctga aaattaacaa tttcttcgaa attgaatttt ctgtccacgc accactttct
    14101 ttattcctgt cttaacaatt tcttcgaaat tgaagccaga aataaagaaa gcctgaactg
    14161 caccacgccc tgcgtcggac tcgcccaaat tcgcaaagcg aatttgcccc gcccttcggg
    14221 ttgctacgca atcctctgcc tcagacttgt gcccgtgtta tttcagccag acattcatcc
    14281 tcggctttta ttgctgcatt atatctgtct tctgttattt cataaccttg tgaagcagcg
    14341 taactaatca gcttattggc atcagaaatt ttcagtttcg ctgtgtgttc aattacccct
    14401 cgcattaacc tcgcttgata tatttcataa tatagtccgc atcccctgtt tgctttatta
    14461 ctaatgtcat caaagactct ttttacatgg attctgtcct gattccttga atgaatatta
    14521 ttaatgaaca tatcttcttt taacatagga ttctccagat ttgaaaaaat atgttaattt
    14581 tttctctccg attgcaatgc taatgcttca gattctgtaa tgagagtaat atcagggtgt
    14641 cgtttcttta aatcttcaat cgtttcacca atagaagtaa tgaattttcc tttcattcct
    14701 gatggaatgg agtgtactat cttgtgtgca tagctataaa caagatcgga gtttgtcaga
    14761 taaaatacca tgtttttatc tgtatccata tttatcctcg gactctacca aacttactca
    14821 ttatttttga tatggctgcg ggatcggctg atgaacactg atttaaaaat gctttacgtg
    14881 catcaaatgt tttactccat cgtattgaac ctttcttctt cttaataata ttgaagaatg
    14941 ctttttctgc tgatctgcat tcgctacctc cgctgtttcc tgtagctttt ccgtacatac
    15001 ataaaacaac ctcgcatggg tctgcggcat aagagtaaac aggtgtggcg gttgttaaaa
    15061 caaacattgt tattgctgct atttttttca tgtcagaacc ctttgtttaa tatatttgtg
    15121 ttaacgcgaa aagtagatgg ttgtttcatt gcacgtaaga caatttgtga tggggtgata
    15181 tataattacc ccgtttgcac catgatgata caaccagttt tttgcgatga aatagtcagc
    15241 gcctgacttt gttgctactg tgatttgtgt tgagtgagca atggcataaa agacagatgg
    15301 catccaatct tctttattga aatcttgtga gctaatggat aaagtccatt tatcattaat
    15361 aacaggcgat tttattatta agctattggg gttccattca ggaagtttct cgttaagcga
    15421 taccggcttt ttattccatt ccacgggtac tggtggaggc ggtgaggaac atccggtaat
    15481 tagtgttaca agcacagtaa ccagtatatg ctttatcata ctttcatttc ctcgtaatat
    15541 tgattgcggt gtaacggtcg gaaataaata tcattcatac ggcgtatgtt tccatctaaa
    15601 tcaatgctca caacaacatc cagagagtcg agaactttac gtagcaagaa tgaatatggt
    15661 aattgcgcac actgtgggtt ttcagtacag cgggtaataa aaccgtcgat tgcttcatgg
    15721 gctgaaccag catgaatgga ggtcatactt ccttcatggc ctgaccccgt tattttcaga
    15781 aaatcccatg cctctccacc cctcacttct gttaataaaa ttctgtctgg attcatccgg
    15841 taattccagc gtataagcgc cgctggtgtt acaacagatc ctttttcatc ggatgactca
    15901 gaaggataaa acagatgaac atagttctta tgtttgtaga atattatctc tgggttgtct
    15961 tctatcgttg ttatgcgtaa atggacgggt atatattgta tcaacatttt catgtatgtt
    16021 gttttacccg tactggtttc acctgcgacg gctaatgttt ttccatactc cacgcatttt
    16081 tccataaaca aaggaatgtt ttttgagttg tataattcaa tcagttcttc gttatgtgtg
    16141 gatgcttttt caatgcctgt gacgcggtta taaaaaccgc tatcaatata tgcctgatgc
    16201 ggaatttgaa tttttgacgg tttacggatc gtgattgaga ttgtgtcacg ttcgcacgcc
    16261 ggaggaacga caacctgaca tcgttctcct gattccaggg ttgcagaaag tcctggtttg
    16321 atatcctcga tattatcgtt atggtgtttt gcaagacacc gagcaaagtt atagcaatcg
    16381 tcaaatttca gatcaactgt atgttgcccc cagacgccat ctatctttgt ccagagttca
    16441 cctggacgat taacagctat ttccgtcaat ccaggaagct ccagaaagtc gccaaagaaa
    16501 cgctgtttat agcggtctag ggaaatattc ttagcggtca tcgtttgttc ctttcagcgt
    16561 gattctggtg gtgcactgct gtaaacggcc agtgtggttt tgcttttaat cagacgctgg
    16621 taagcatcct gtgcggcggc ttcgttcggg ttcccggcga gaacacccat gtgtccggcg
    16681 gcgagcatgt gcaaccaaat ctctttatct ttgcagttca tttttcatcc tcagtgtgta
    16741 gatatttgag aagtcaatat cctgccctgt aattaggttg attatttctc cctgattctt
    16801 gtaaagcgtt ggtggaatat taatgctgtt ttccagcgtg gttcgagcca tatccgccat
    16861 agcctggcgg ctgttctctg tatagtctgt attgcggtct tttttacccg cattgtttga
    16921 tgcccatgcg ccaatatctg ggatcatgcc gaccattaat gcgccgccaa acctctccca
    16981 gaagtgggta tcaatccatc catcaacacc tgattctcca agctcgccag cggcgttggt
    17041 atcaatcagc ggaatatcca gatatggtcg ctgtcgggtg cgtaattttg tcatcatgat
    17101 aaaagcgcgc ccctgccctt gcgtaattcc tgtctggtat attcctgttg ctgtggttcc
    17161 cttctcgata agttttgtat tgccgctggc actccagata tctttagcta ccgtacatcg
    17221 tatttttcca gcgcgatcgg aaacaaagcg gtaatccata gaacatggaa tgactgtgtt
    17281 ttccggtatg tacaaatcag ggttgtaggg gattcttcgc actgtcgcgg gggaaattgc
    17341 ctgtgatgca gtgccatgtt gtgttgtggt tgctgtactg tctgtaggct gtgtggcgtt
    17401 gttttccgca gccagtatca tttcctgttg tcttgttttt acctgatttt gggggctggc
    17461 cgtattatta cgacgaacaa ggaagctggc cttattcagt tgtggtggct caaatgtttt
    17521 catctgtccg gcagtaccgg atacattgcc cgtgttatct tggctaacag cttgctcacc
    17581 atcagtcgaa ttttccggct cattggtggc catgcctaaa tcggttcgtt tccggtagtc
    17641 attcgttttt ttaggtggcg taacctcctt tgttttctct ccatcttctt gtttcaggaa
    17701 gttttgatat acccagttac cgccccatgt caggccaatc agggctactg cgcatattgc
    17761 cagaaaggcc gttgctttcc ccttctgacg ttttttcagt ttgtttactg ctggttgtaa
    17821 tgagttctcc ttttcatcgt cctgtgatgc ttgtaattca gcctcacgtt ttgctctggc
    17881 ttctcgttcc agcgtggcga tatcatcctg atcagatgtc gtcactggct tttcttcttc
    17941 cgtagagggg gatttatttt cgtcagtcat atatgagtcc ttatataaag atataattat
    18001 atttttatag attaggtgtt atctgttttt tcaacgcgct ctaccttgtt agatacggtt
    18061 gaattatcag ccgcgtgtac ctttccaaag ccgttatttt tcaaccccac tacggcatca
    18121 ccggaacgta gtacaagccg tggtgtgata tcctggataa cgagaacggt aaaattgccc
    18181 ttacgctgta tactgctgtt aactacgtat tcctggccgt tctgttcttt ggtaactgat
    18241 ggaactgatt tgttgggtga gaatccgata aacgtaaagc gaccgtcgtc gtaagcaaaa
    18301 tcaggttcaa tgctgtaact gtcttttcct ggatatttcg tgtagtccca gttacgcggg
    18361 gtttgtgcgg ttctcagtgc tttctgaatc tgggcttgtt cctgcttttg ttcccattct
    18421 ttctgacgtg ctgctgcttc cttattggct ctgttacgtt cgtctcctgg atagcggtaa
    18481 ctcactaggt atgcgggctg ttgtggcgat ttttcatcaa tgacattcag ttcaacgttg
    18541 tacaggcgct tatttgtcac aatcagcata ttggtatgcc agtcacggct gttcggcggg
    18601 ataacaacct gtgttgtatt accgtcttca cctggtgcgc cctgtgtgag cgcaacagga
    18661 cgaatgttaa ccctgtttgc atctgctctg gcttcccatg cttcatcaaa gccaggactg
    18721 gcactgataa cagcttcatc gttatcaaaa accagagtcg tcataaatcc tggttttgtg
    18781 tttacaacgg taacattctg cgggttataa atgacctgct ggatacgtgc atcataacgg
    18841 ctcgcctgtg gtgtagctgc ggcccatgct tggctgttca gcattattat cagggtaatt
    18901 aacgtcagtt ttctcattac tcgcctcccc tgatttcgcg gtcagtctgc cagcttgtta
    18961 cggtgaatcc gaacgggttt atttcccgct caacatctga catttctttt tcagggtctg
    19021 aatggaaggt gaaacgtgca tcccagtatt cattgcgaat actgttatca gccatgcgac
    19081 gaattatttt tttataacga acggtggcta ctttgtctgg tgctgttgca ttcgttatct
    19141 gctcagaaat aatttcaatt ttcacggtgt gagccgcgtt attataaact ttgtctggtg
    19201 cgttttttcc ggcgtacagc gctaggtagt cgtcgtttac ctgtggtgag ttgtagatct
    19261 gtactgtctc gtaatcgtcc tgtaatgcag gataaacgta ccgttcacgt aatttaacgt
    19321 aattggcggc catagctttt tggtaggctt cttccgctgt cagggctgtt tttgatgcac
    19381 gggtaacgtg ttccactcgt ccggtatgat tatctacggt atagagttca acagttgttt
    19441 gtttaagtgg caacataatc actatcgcga tcagtgacag gatagcgatt aataaccctg
    19501 ctccaccgac cagaaagcct gcctttgtgg cgcgtttatc cctgtcaatc atttgctgct
    19561 caaacgagcg ggaatcagca attaatttct gttcagtcat gtgtggttag ctccgcgata
    19621 atttgggggg tgtttacagg gctaccctgg ccgctgaatg cgggcggcaa aggtttagat
    19681 ttttgtgcgc agccggaaag cacgcacagc aaagccagcg cgattaagcg tttcatttta
    19741 tgtacctttt gttttttcta taaaaatata attatatttt tatagttatc ttggaggggg
    19801 taaacgttta attgatggcg gtagttttgg tgttgattga tctgtcagca tccgcgcttc
    19861 attacgcgct atcatttgtt ctatagcgtg tttacgtgca tcagcagcgt taaatactat
    19921 gcgcgattgt ggatctccta accctttatt acttgggctt gctacttctt taggtaatac
    19981 ttttcctgcc tcctttaaca tctttccagc gccgtatgca gcagcgccaa tgccgagagc
    20041 cgccgcacct tgcatagtgg ctgtagcact tgctcctgca agtgccccag ccagttttgc
    20101 ggacatgtac accagtattg cagcgcatac tccggcaaga caaacttgag cgccaagttc
    20161 tacaatattc gcttgattgg ctcctgagga tgctagagca agccttgaat ttaaatagct
    20221 tattacaatt cttaatgata atgaggacag gagaatggtt aatattcccg caaatatatt
    20281 ttgcagccag ttattgaaca ttggccgtaa aaagccatac attaggcaaa atataaatat
    20341 aggtgctgta attcctaaca ataagatcat aacctccgca accatagata cgaatgcagt
    20401 gataatcatt aagacaaata caccacccca tacaaataat tcagcaattg ttccctcatc
    20461 tttgataaat tctgaatcat ctaaatcatg taatgttttg cctaatacct tggcgttgtg
    20521 ccataaagtg tcgagtaact gccagatact tgaactactt gaaaatcctt cttttaaacc
    20581 attaacagca tcaataacac catcaagata accattaata tttgccacaa aggataaaat
    20641 aatagccatc ctcattatat cccacatgac atcttccatt ggggtcgaca gtttaccagc
    20701 taaggtttga tatcctctcc atatgatgta gattgtggct gacgttcccg ccagccccat
    20761 catcattgaa gaataagaca tcattaaacc ttgggtagcg tctgttatgc ctcctatcag
    20821 atgtttttca acaccgacaa aaacaccacc agacatttct cctcctattg attcaaatcg
    20881 acggttggcg catttaattg ctgaatttgc cagtgagcct cattagcatg tttacagttt
    20941 tctgatgcgc tacctgtttt ttggcatttt tcgtaaacag cttttaattc atcggggtgc
    21001 gttcgatacc actttgttgt ttttgcttct tcctcgcatc cattaattaa aaaagctgat
    21061 aaagataata gagttattgt taataaacgc atttttcatc cttaactgtt taaatcaagt
    21121 gttggagcgt ttaattgctg ctgattccat ttcttacggc gttcctcagc aagcatcttt
    21181 tcacgcttct ccgctgcttt tacgttcatt tcccattggg tcgtgagcgt atttaacatc
    21241 acagatttta actgaatact gtttgctaag tcttgggcct ctttcatatc tttcgcattt
    21301 gctacacggt ctgataattc gttgatctca ccaagcatct caccaatctg tgtttgtact
    21361 tcattggttt gttcgatttg tattgctttg ttgatgacct cttgtctgca tgtattggcg
    21421 taactttttg attgttcagc attgcagtta tcgaaaatct tgtatttgtt gtacagttca
    21481 tcaaattggc cagaagaacc gccggataag agcaaatcgt tcagggcttg ccctggctta
    21541 cgtagtttat ccaggtcagc tttaaggctt ttggcctgat taacgaacgc ctgaatgtca
    21601 cggatgcctg taactgtttc cagttgtttt tgatacgcct gtagctggtc tttatagtgt
    21661 tgtaccgtct gtagccattg attggcttct tttgtccact ggcgaatatt ctctagtctg
    21721 gctgttgcat caaacacggg tataccagca gcgtttacta tcgggctggc aataagaacc
    21781 gccagaataa gggggcgaaa tcttttcatc gatatctcct tggttatagt gctttagcta
    21841 ggtaggaatc cagccagtcg ctgggcttca ttccctcctg atagagtgat tcgaatattt
    21901 ccaggttagg tgcgtcgccg ctcattactt ttgtgtatct gccgatacca gacagatcca
    21961 gcgtgatacg ggctgcaaag cgttttgtat ctccacggcg gaactgattt ttgacaacga
    22021 catactgtcg cgcctgtgga tcaagtcctt taatgacatc aaacacttct ggttcaaatt
    22081 tcattccatc cacgtaatga gaacgatctg cgcttgggtt ggcggccagt atttgagtac
    22141 cacattgctc aataactgcc ggagctatct catccttgat tatttccgct ggagattgcg
    22201 tgccaacaac cagcataccg ttcagttttc gtatagtttt cagcttgtta tacgcaaaat
    22261 ccttaaatac agggtcgcgt aaccacttcc agaattcatc catgaaaata acaagtcgtc
    22321 tgccatccag caggctggtt atccggtaca gcagataaaa cgagataggg gcgcagacat
    22381 tcgggtcatc cagaaattca gtcccgtcaa ttccgaaatt atcgcagttg ctgatatcga
    22441 aagtgtcgtg ttcgttatca aacacccaac caaattcacc accgcgcgcc cactgtgaaa
    22501 gacggatact caggccattt tcttgcgctt cacgcgttgc cggttccggt aggttctcca
    22561 gcattcgggt tatgccgtag acgcgatatt gaggctcgtc actcatgacg gcatttacag
    22621 catcattgag gcgacgttca tcacgtggcg ttatggttgc accgttgcgg gtacaaagga
    22681 ttttcatcag ttgcttaatg aaattgatgt ttcgcttagt ggctggcaga gcaaacggat
    22741 tccagcctgt tggctcaccg ctgaataccc tgtagtactt tcctccaagt gcgcgaatgt
    22801 tgatttcagc accacggtct ttatcgaggt aaactgtggt tagtcgttta gtcctggcat
    22861 ccggtgaaaa gctgtcatca cggttatatt tttgctgatt gatttgtaaa aacgtcatca
    22921 gcattgtttt acctgagccg tttgtaccca gaatgcaggt acttgcagga tttttttcgt
    22981 tgaactcgtc tttatctgcc agagtgttat gcagattcag atagtagcca tcacctgacg
    23041 gggttcgcac cagagccatc gcgtcacccc acggggcttt gtcgcgtttt cctggataga
    23101 aattatgaag tgatgccagt tcaacaaagt tcaggctact cagctctcca gctcgtggcc
    23161 gcagattgta attgcctggt aattgagcca tataggccgc agacaatgag atttcagcag
    23221 gaacaggggt tatcccgata ttgttaagtg cattgctgat ctcgtttgtg tctgcaacca
    23281 ggctttccag tgacggcgaa aacaccataa ttgataaatg atgtttaccg taggcgattt
    23341 taccggaggt aagtaggtca agcgccacat cgagatccag acgttgagat acagcatcat
    23401 catcagcact catcatcagc cgtcgggtgc gcttaatcgc cttttttgct tcctcacggg
    23461 acatgcaggt ataggattgt gtaatcacat aatcgcacgg cgcgtacagt aaggagtctg
    23521 tcatgcccgt tgcggtttct tccgaaaact ctttaacctc cagaccacgg aaatattgag
    23581 tgccattaac atgatttatt tgccctgatt cggcggagaa gtacagcgca acatttccca
    23641 ttacgttgta agcgggagta cgtgtaactc tgacttttcg ccattgatgc gtgataaggt
    23701 attcataaaa tgccagttga gacgagaata cagcctcgtt ttcggtaaaa gtaccgagcg
    23761 cgtgagcacc ataacgggat aaggctgtat ccagcgtact tttgatttcc agcacttcaa
    23821 gtaatgcgct gtctatctct tttagcttct gaccgtcttt catacgttta cggtttgcct
    23881 tatccagact ggcaaacgga cgatagcaga tggtcacaaa caggcggtta cgtcggaatg
    23941 gccttttatt cagtgatgcg taatagcgtt cgctcacggt atccgcgtaa gggtttcctg
    24001 aaaccttatg cagtgagtcc gtaaactgtt cacggctgtt atgtacataa aatgtaaccg
    24061 gaaagccttc aaatgagcgt attagcccgt gcaactggtt tgtaccgaac tgtagtgtct
    24121 cgtcagattc acaatcaaac ggcgttcctg tcagttccca ggtacagaaa aaatcgctat
    24181 tcagtgaacg gacaacatta gggtgaatat gtgacgagta aggaatgtat ttttttatgg
    24241 tggcacattg gtttagcttc atcgcatcga taaactcctg gatatcaaca gcattatgtt
    24301 caacaggcat aaatgcggtt gcgccaaata aacggtttgc taccggatta ccccttaccc
    24361 ttagccagac agctatcagg ttaaatctca gaggttcatt tctggttagt gatttcataa
    24421 ccagaaactc aatagggagg aagagaagta gggctatgga agtccagata gcaacaataa
    24481 ttgtcacgcc cacgacagtc agcaggggca ccattggcac cccccacagc gccgccggac
    24541 gtttcatcgc cttaagcagc tttgccatat gttcggcctc ttagctcatt agcagagcgc
    24601 caatttcact gcctccgcca attaaaatgc cgccaatgat gatgtaaccg cactgcgaca
    24661 ggctttcgcc tttccacaga gtcttatagc caatccagat tacagcgacg gtgatggtga
    24721 cggctgccag accatgcaga ccattcgaaa ccttttccat gattgtattt gctcggctaa
    24781 aaccgtcagc cgcgaaaact ggactgacaa cacttactaa cggagccaga atataagcag
    24841 atgcgcggct gcaaatggtc tttaatttgt taaacatcgg ttaatcctct ttttcagttg
    24901 aaaatctgtt tccgcgtata acttgtgcgg ggtaataaac ggtatctgcc tttttctggc
    24961 gcagttgagc aggaaccccg cgcacgattg cgccaggcca gacaacgcga gggcgtgccg
    25021 gagcttcaac gggtgttgca ttcagaatgg ctgattgagt tgcgatatca tccttggttc
    25081 caggaacgac atagcggggc ttttcaggtg agtaaccaat tcgctgtatg taactggttc
    25141 tggataacgc tgcttctggt tgttgtcctg tagtaaaatt tccagagtaa taacaactca
    25201 gcgcccgttt cagtgtgccg cctcgctggt agcaatcagt gatgatcttt tcaaaaacag
    25261 aaagatttgt gcacgggttg aacaggtcag cagccgttac ggcgtaacta ttaaaatttg
    25321 tacttgtgat ttgcatcaga ccaacagaat agcgacgacc ttttgcctct atctgtttga
    25381 cgatgcttaa tgcatcctcc ttagtttttg gcatatgtga gataaagccc ttgtcgcctg
    25441 gctggcgttc acgtttgggg atgatctcag caatagcgta gggattaaaa ccagactcga
    25501 cccgcgcaac atccagtgat gtggaggggt gaactgtggc ggcacactgc atagccaccg
    25561 ccataaatga aacggtggaa agcatagtac cctcgctaaa ttagtttcct tgtggggcgt
    25621 cttctttagg ttcgagtagt accagcttgc cggaaacagc aataccagga acgagcataa
    25681 tattcagtcc tggtttttcg ttatgcgcga atgccgcgcc aaccttggtc cagtaggtat
    25741 ttttaccgcc gttttcgtca gtgggaactt cctgtgtgac gtatacgtta taggtgggtt
    25801 tgggcattta tttatcctct tttgacatta gctctttcaa catttcgttg tgagcttcat
    25861 tacttaattt gtcgatcatg tactgcaaaa aggcacttgg acgaatattt acctccgcaa
    25921 cataacttat atctctggcg tgttttgcca gtgtttcata gcgttttttg ccgatgtaaa
    25981 taacggctgt agatttagcc tggcctatag ggttcggcat gagtttatag ctcctgtatg
    26041 aaatatccgt gtgcaaaagc acagcggtac gactggagaa ggaatgaagg tctggtttac
    26101 tgattctgta aaagcctgga gaaggccgtt tgacgttcta acggtgagat gattgaagat
    26161 atgcgttgaa tttctgccag taggtcacta ccgatgttac ggcactctat agaatcatca
    26221 tcaggattta gcgccagtat cttggcgcat ttaatagcga taacgacttt ttccggtaca
    26281 gtacatattg tggaaccgaa acttacgaag ccaattgcac ctggaataga ggttattgct
    26341 gacgtgtgcg tgacattcac atcaaaatgg aggaagaggt agttaggaaa taaaactttt
    26401 tcttccttac gcactgcgtt gcaatctttc cgaggtgtga actttatgta tctcggacag
    26461 aaagccacaa cgttcatagt tttacaacga tatgcaatac gatctaaatc gttgttatta
    26521 cagtataaaa gataccatgc attcataagc gtcaccttac ggacacaagc ccccattttc
    26581 cgccgtccta agttgccggg cttaggctga cgtactcatt aagtgttaac tgtaaaaata
    26641 tacagttgtg atcttataca gcaattcttg cgtgtcaata tcaagaatct aaagaaataa
    26701 taacaagaat gttcattaag tcaaaacctt tgaatgtatg aacattcggg ggttggtgcc
    26761 gatgtatgtt ttggaaaaca aaacaagggg ataggtcaat ggtgccaaaa cgattgaaag
    26821 aagcgcggga agctgctggt ttatctcagg aaaagctatc agagttagtg gggatagaag
    26881 ggactagcac aagatctagg atgtctaatt atgaagcggg acggtttacg ccaccattta
    26941 aatttatctg tcgagtggca gatgtcttag gatatccaga atattatttc tatatagtga
    27001 atgatgtaac tgctaaaaag ttacttcaga tgtacaaggg agaaaaaaac agcattgaaa
    27061 acattgagtt ggaggcaagt agaatggctg atcaacttga tgatgctaga aaattagtat
    27121 cccaacttag cgactgtgtg agagagctta aacgttcgtt agggtaagtt tcgggcatca
    27181 gtgcgtatgt gctccatttg gtcaagtcgc ttttccgctt cctcacccac tcgctcacta
    27241 acgttcggtc gctggggctg cggcgagcgg taaatactct tacatatttt tatcaaaatc
    27301 ctttattttt ccgtttgttg tcgccgattt tttttcgata ttaatgctaa tgtatgcgta
    27361 cattagcatt aatatcatga gttatgtgct gtacggtatt taatctcaat tttgttaaga
    27421 gttatataac cagatgaagt gtaaagaaaa atagtaaggt aatcggcggg atcttttgtg
    27481 gatgaattga tcttcgaatg ggttcatgct attttcgtgc ggtttttacg gatttttggg
    27541 tgggacgttc ccgtaacagc gtccaaggga agggggggaa gcattttagc ccccctgaat
    27601 gcaacaaccc cctgatatct ctcttcgatt ttgccggtcc aagaagataa tcagggggtc
    27661 caaagcaggc tgggtgcctg caaaggatta tagcaaatgc atttctcaat acaagacctc
    27721 tgtccggcaa taagtgcggg cg
//
