LOCUS       CP097398                9294 bp    DNA     circular BCT 24-MAY-2022
DEFINITION  Klebsiella pneumoniae strain KPN132 plasmid pKPN132_3, complete
            sequence.
ACCESSION   CP097398
VERSION     CP097398.1
DBLINK      BioProject: PRJNA788509
            BioSample: SAMN28448992
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Kochan,T.J., Ozer,E.A. and Hauser,A.R.
  TITLE     Klebsiella bloodstream isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Kochan,T.J., Ozer,E.A. and Hauser,A.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2022) Microbiology & Immunology, Northwestern
            University, 303 E Chicago Ave, Ward 6-035, Chicago, IL 60611, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 49x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/17/2022 09:28:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.1
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,358
            CDSs (total)                      :: 5,236
            Genes (coding)                    :: 5,131
            CDSs (with protein)               :: 5,131
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 41 of 105
            Pseudo Genes (incomplete)         :: 62 of 105
            Pseudo Genes (internal stop)      :: 15 of 105
            Pseudo Genes (multiple problems)  :: 11 of 105
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KPN132"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKPN132_3"
                     /geo_loc_name="USA: Chicago"
                     /lat_lon="41.87 N 87.63 W"
                     /collected_by="Fiorella Krapp"
     gene            complement(join(8832..9294,1..1502))
                     /locus_tag="M8J57_26740"
     CDS             complement(join(8832..9294,1..1502))
                     /locus_tag="M8J57_26740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="URB92296.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(2983..3132)
                     /locus_tag="M8J57_26745"
     CDS             complement(2983..3132)
                     /locus_tag="M8J57_26745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology. GO_component:
                     GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="URB92297.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(3217..3474)
                     /locus_tag="M8J57_26750"
     CDS             complement(3217..3474)
                     /locus_tag="M8J57_26750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="URB92298.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(3484..5169)
                     /locus_tag="M8J57_26755"
     CDS             complement(3484..5169)
                     /locus_tag="M8J57_26755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="URB92299.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            5572..5991
                     /locus_tag="M8J57_26760"
     CDS             5572..5991
                     /locus_tag="M8J57_26760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="URB92289.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            6297..6560
                     /locus_tag="M8J57_26765"
     CDS             6297..6560
                     /locus_tag="M8J57_26765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="URB92290.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="plasmid stabilization protein"
     gene            6550..6849
                     /locus_tag="M8J57_26770"
     CDS             6550..6849
                     /locus_tag="M8J57_26770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="URB92291.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6911..7288)
                     /locus_tag="M8J57_26775"
     CDS             complement(6911..7288)
                     /locus_tag="M8J57_26775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="URB92292.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="entry exclusion protein 1"
     gene            7357..7536
                     /locus_tag="M8J57_26780"
     CDS             7357..7536
                     /locus_tag="M8J57_26780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="URB92293.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(7564..8094)
                     /locus_tag="M8J57_26785"
     CDS             complement(7564..8094)
                     /locus_tag="M8J57_26785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="URB92294.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8101..8832)
                     /locus_tag="M8J57_26790"
     CDS             complement(8101..8832)
                     /locus_tag="M8J57_26790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-relaxation family protein"
                     /protein_id="URB92295.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="replication-relaxation family protein"
     BGC             1..9294
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          2302..2880
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(8105..8832)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 gactggtgcg cgagcaacag attgcagtcc cggctgcgca gcgtccccag tgcgttcagt
       61 acatacttcg acagcagata tttaatttca tcgagcatca cgctgacgtg tggccactcc
      121 cggaactcgt cccgcgcaat gatgatttgc gcgcagcggg caaacagcat tttttgcaca
      181 cggatcaccg cctcgtcgtc catcgagccg ataacgtaca ggcagccgcc gccgttgata
      241 atccccgcca catcgatgcc actgtccgtc tgcaggacgc tcaggtcagc gacgttttcc
      301 agcctagtga tcaacccctt cacgtccttt ttcagggcct ccggcagcgc gtacgccgcc
      361 gccagcacct gctgaatgtt tgccccctgc ggaaactgct ccgcaatcag cttcgccgct
      421 ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg tctcgcccag gttaagcccg
      481 gcaatcagca ggtttttcag cgcgtactgg tcgagatcgc ggaacagatt cagctgcgcc
      541 ggtttccccg gccgcagatc cagcagggtg aagtccggac agtgcgcccg gaagacgtgc
      601 ggcgcccatg cgtccccttt ggggtcgaag tacaccaccg cgtccccgaa atcgcgtacg
      661 cagcgaatga gcgcgttggt ggccatcacg ctcttgccgc tcccgggcag gccgaggatc
      721 tgaatgttgg tcttgcgcca ggtatcacgc ggaaccagca ccggcttgcc ctgctcatcc
      781 ttacccagaa acaccgcctg ctcctgccgg gcctgctccg aggaaaaatc ggccagcgca
      841 ttaaccggta ccggctcccc gaaatgcagg tggcgcacgt cggtcatctc tcctgtccgc
      901 tggctgctgc gccggctctc ctgattcagt ttcgcgttca ccgcctcgtc agcagccgca
      961 aaatgaccgt caagcagcag gaacgccagc agccgcgcca acacaatccc gacagccagc
     1021 ccgcccgcgc accaggcaat cccgaacagg ttagccggct gcagcaggta ataatctgcg
     1081 tttgcgtaga ggtccggacg caggacggtt tctccccagc tctcgataaa cacggcgaca
     1141 accagccccc ccagaagggc cagaccggcc gcgccggtca gccagtacgc gtagttccag
     1201 acatgtcgac gtgccctgac catccgcccg ggcgaatcca gcgaggccag caccgaaaat
     1261 ggcgctggcc gtttattatc gcgcttatag cgatcggcat actcccgtcg ctccttatga
     1321 ctcagcccca caaaacgcat ccgtccggcc caaagttcag ccagaccgaa aaacaggccg
     1381 ataactagga aagccccggc cagaccgtaa tactcctggt acagccagct gacccacgga
     1441 taaatctgcc gggccagctc cggaatgtgc cacttccagg caagcgaatc cgtattaaac
     1501 atgttctctc tccttcagac gatggtttgc cggcgtgatg tgcagccccc gctgcacaag
     1561 ccgcggacat gccccaaggc atggcggcgg cggtcacgtc cgtggtgatt gcgttcagct
     1621 ttcaccacgg aggccagcct ctttccgccc catgcggaaa aggcgcagcc ccggaggaac
     1681 aacgagcacg ccccagcgtg tgagaggaaa aggcggcacc ccagtgcggt cttttccggt
     1741 gttccggccc ccgtcagagt tcgccatagc gagcggctga ccacccgcaa aatcaggagc
     1801 agctttgctg cttcgccagg tgcgtccagc accgtggatt tttgtgggtg gtcaggcgtg
     1861 agcctgacgg gggccgggtg aatttctggc gtggccggcg tccagccgga cggagccaga
     1921 aagaggggga gagaccgtgc gtcggtggcg tccagccagc gtaagcaggg gatatccccc
     1981 tgaggtcagc cacgccctcg cggggatgac ctgtatttct ccgtaaggag aaaaaagcaa
     2041 cagagatagg ttaacgtaaa atgttcagcg aaaaaccgat atgattcacc tatcctggta
     2101 atttattatc agggaatata aagacttaat caggggacaa tatgccacat cagcgcgtcc
     2161 ggtgtccgtc ttgtaggtgc cggggaaatt gcgcctcctc gctcactcgg tcgctacgct
     2221 ccggccgtga gactgcggcg ggcgctgcgg acacatgcaa agttacccac agattccgtg
     2281 aataagcagg ggactaacat gtgaggcaaa acggcaaggc cacgcaggtg gcgtttttcc
     2341 ataggctccg ccctcctgac tgagttcaca taaacagacg ctttttcggt gcatctgtgg
     2401 gagccggtgg ctcaaccatg aatcagtcag gagtggcgaa acccgacagg acttaaagat
     2461 catcaccgtt tccgatgaat cgctccctct tgcgctctcc tgttccaacc ctgccgtttc
     2521 ccggatacct gttccgcctt tctcccttgc gggaagtgtg gcgctttctc atagctcaca
     2581 ctctggtatc tcggctcggt gtaggtcgtt cgctccaagc tgggctgtaa gcaagaaccc
     2641 cccgttcagc ccgactgctg cgccttatcc ggtaactgtt cacttgagtc caacccggaa
     2701 aagcacgcaa aacgccactg gcagcagcca ttggtaactg ggagttcgca gaggatttgt
     2761 ttagctaaac acgcggttgc tcttgaagtg tgcgccaaag tccggctaca ctggaaggac
     2821 agatttggtt gctgtgctct gcgaaagcca gttaccacgg ttaagcagtt ccccaactga
     2881 cttaaccttc gatcaaacca cctccccagg tggttttttc gtttacaggg caaaagatta
     2941 cgcgcagaaa aaaaggatct caagaagatc ctttgatctt ttctactgaa ccgcgatccc
     3001 cgtcagttca gaggaggacg atggtgccac cgttccaccc tgaacatccc ggatatagtt
     3061 tgcctgacat gcgaccagaa gaaagcctga aaaaatcaat ataaaaagaa aaacaacctt
     3121 tacctttttc atataccttc cctgtattta aaaaccccgg tattcatccc tgaacaccgg
     3181 aagtctgtat ttcaaatcat ccttgataac ttttgcttac cagttaccat cccggtaaac
     3241 aaaggataca aagtaatcaa atttactaat atcgattaca tttttaaagt gtggctgtaa
     3301 tatcgaaacc catgattttt caacatcaaa ccaaccatta ttaatattat cctttaaagg
     3361 catccccaga ctttcaatga cagaaccatc atcaccgaag tcttttgagt attcaccacc
     3421 tttaaactct tcggttttct tatcaaacca atgaatatgt aatttaagcc ccatatttac
     3481 ctcttaaaga tattttttaa tgtttcgttt tggatccggc cctttaacct gcttacccgt
     3541 ttttggatcg aatgccccga ggtgttcgcc atcactggcg cggtaccctt caagctcacc
     3601 gtgctgggaa tcccattcat aaattttacg ctttttatca ccataccatc gggcccgctt
     3661 accaccacca ccttgtttag gggttttagg tttaccctct ttcaactctc ccaacccctt
     3721 aatatcttca gtcttgggat caggaaaata atcatggccg taatctttag ttcccttacg
     3781 aggttttttc ttttcctcat ttaatttatt ttctgcatcc ttcgcttttt tctccttttg
     3841 tttccggctc tccatcgccc cggaaagcgc agccttatcc ctggataagg attcattcat
     3901 ttcgtttaaa gatgtctggg cagcttttaa tttctcattc tgattctgaa tatccttatc
     3961 aagatagcga acctgatcct gccacccgga gccatattca tgaggcgggt tataagtcac
     4021 aaaatcatct ttatttgcct ctgcctcttt taccttttta tcggcttcct gaacagcagc
     4081 ccttgcaccg gggatcgcct tctctgtcga tgcaatgcga ctgtttaagg tcgcaatatt
     4141 tttatcttca gcatccagct cagctttcgc tttatcatac tctcttttca gcccctcttc
     4201 cgggtgagca gcgtcccatg cctgctggcg acgcttttct tcctccagac gctgttttac
     4261 ctgtgccgga gtaagaacat ccgtcaccga cacatagacc ggtttctgtc cgctctcttt
     4321 cgggaaacga ataacggcct cacgggagtt accaccggcc gtaaaaccag ccggacgtga
     4381 atcacctttt tcagcaataa tgccttttgg cggggctttc gcggccggaa cacctttagg
     4441 tacgctcacc tgcagagacg ggagacccgg aatcgacaca ctgaataccc ccggacgttt
     4501 tgtcggtttc gcatccacca caggaacact cattggccgg ccggtgacaa ccgcaatatg
     4561 ctgccgctcg tccttcacaa tatccgccac acgtttagtg acgctgaccg tcgcctggtc
     4621 cagcggcagg gagctgaccg gcgtctccgt taccgtgtct gccggcaatg acgtcacgat
     4681 ttttgacatc attttcggat catcttttgc tatctcagaa ggcagcactc cgtaaatcgc
     4741 aatcccccac agaccaaact taaacggacc tttcagggca gccagcacat cagcaacagc
     4801 ggccgacaac gcatcgccgg aaacggataa agccagtcct tcagcccccg gagtggccag
     4861 ggcaggcaga ccgaaggcca tcgcggtggc cgaagactgt ccgccaccag agctcccgct
     4921 atgattgccg ctgttaccgc cattaccacc gggtttactc ccgccgttac caaactcccc
     4981 cgggttatag ttatgaatat ccccgttagg tgtatgcgtc gtaccccagc ccggcccgct
     5041 gtttggatcc gtaccaccac ctgatgaagg gccaccttta cctgatgtac cgttcacatt
     5101 cccactggcc tgaccaccat tgtgtcccag acctgaatta cccggacctc gtccgtctcc
     5161 gccactcata tacttttcct ctttgacttt taaaacaata aactaaaata aaatactgta
     5221 catataacca ctggttttat atacagtaca aaaattacgc tgccttgttt ttcatgtcaa
     5281 gtctgtaaat ttgcgttttt gtgaaaatga tcaaaaaaac agccactcac accatgcgca
     5341 atcccctcca gatgcaacaa aaaccagcac aaacggcgcc gttctccggc ctcagtatgt
     5401 tttactgaaa tcattatatg agataccaga aagccccctc cgggacagga aaagaaacgg
     5461 ggggtctggt tcgggttgtt cggtcactga acacggtcag aaactgatga taagatagcc
     5521 tgcggatata taactcaatg agaaaaaaga attaaaggta aggagacgct catgagacgt
     5581 tccggcagca aactgtgtct tatcgccatg ataacagcga cagcaactct cactgcctgt
     5641 gctccaaagg gcagcgtgga acagcatacc cggcattacg tatatgcttc agatgacggt
     5701 tttgatccca atttttccac ccagaaagct gacacaacac gaatgatggt gccttttttc
     5761 cggcagttct gggatatggg cgcaaaggat aaagcgaccg gaaaatcacg gagtgatgtg
     5821 cagcaacgca ttcagcagtt tcacagtcag gaatttttaa actcactcca aggcacaaca
     5881 caatttgcgg gtaccgatta ccgcagcaaa gacctcacac cgaaaaaatc aaggctactg
     5941 gctgacacca tttcagctgt ttatctcgat ggctatgaag gcagacagta agtggattta
     6001 ccataacgcg tcattacgcg caccgctcag acgggctcag ggcgtttccg gcggctacgg
     6061 gataaaacag gcaacaaccc ccccggaaaa ctgccggaaa cgcgcccgat aaattttatc
     6121 ctaatgcatg cctatgcacg caactgcatg gcatatgttt tgacgtaaaa tggatgccgt
     6181 aagccctttt ttaccgactt tctgcttcat cagcctgact gacacgacca tattctttca
     6241 gaccgccccc tgctaaactt ccttcatatt gccgcattaa cccgggaggc tccgcaatga
     6301 gcaacactac acactacgaa aacgccaact ttcttcggga actggctgaa agcctgcccc
     6361 gcatactgcc ggaaggtggc ccggacaaag ctgcgctgtt gcagcgactg gctaacgaag
     6421 aactggccca ggcagagtat gaagatcagg ttcgcgccaa agtgaccgcc gcccgtgctg
     6481 acacgcgtcc gggtatgacc acggaacaac tccgccagcg cctgcatggc cgttatcagg
     6541 aactgcgcga tgccgtatga cgtggaatgg aagcagggag ccatcgagga tgtaacgacg
     6601 ctgtttgact atatcgcgga aaattcatcc ctgtgggatg cgcagaacgt taccgaccgg
     6661 gttctcgctg cggcggacaa actggccgac ttcccgcgac tctatgaagt ggactcacgc
     6721 tatggcgagg acgttcgccg gatcagtctg atgggacagc atgtcctcta tgatgttgat
     6781 gaccagacca gaaaagtccg ggttctggcc gtggtcggcc agcgccagaa tccccatatt
     6841 gttctctaat aaccggtgac ggggacgcaa ttcattgcgt ggccgtcgcc ggttggacaa
     6901 gcacagcgcg tcagcgtttt ccccacggcc accaccggcg cggtgttccg gccggggtct
     6961 ctgctgtctc cggtttgtgt tccagcagtc tcatggactg catttcctgc cgtagcccgg
     7021 ccacctcctc cctgagtgct tttatctccg cgatcaacgc gtcggaggcc attttttcag
     7081 tctcacccga cagtctcaac tcgtcccgct cgtgagtctc atcctgtctt aactcaccgt
     7141 acacccggat aagctcgctg gtatccacca cccggccgcc atcagcttcc gtacggtatg
     7201 atacgcggcc tttcgccata tcccgataca gggaacttcg ggctttaccc gtcagttccg
     7261 tcgcctgtct caccgtcacc cacgccattg tctcaccccg ctatttttga gacagtatac
     7321 ctgacaggcg cacaccatgc ccggaaggaa agaatcatga caaaacagga aaaaacagcc
     7381 ctcaatatgg ctaaatttat taaggagcag tcgctgctat tgctcgataa actgaatgag
     7441 ctggatatgg ataccccggc cgacatgtgc gagcggctac acgaggatgc ggaaacactc
     7501 tggcaggtga tgcgggataa gctcggggag gaataacagc accggcatgg ccggtgctgg
     7561 catttatttt ttgccgaacg gccaccaccg gcgggcaggt ttgtcctccg gcagttcagg
     7621 taccggcacg ttaaaatagc ggctgttata ttcccgcatc agctccgctt tcagcttctc
     7681 gttcaccgcg ctttccccgt gccgctcact caccacgtca atcatcgcgt taatctgctc
     7741 cggtgagcac ttcccggcat caaccacctg cacaccgttc tcgatggcga accgctccac
     7801 cttgcgatag aggtaatcac acagcttcat tcctgtgggt ttgttccgtt cccattgcgg
     7861 atttttacca gtgaaaaagt acgtggcttt ttcgtcgctg ttgagccgct cgtcatacat
     7921 cccgatggat ttcatcatcg ccagatgctg ggcccggtcg acaaaacaga aaacatacgc
     7981 cccggtctgc caggcgagca ccaccatatc ttccagatgc tcgctggtcg gcatgatgca
     8041 gcgctcgccg ttccggtcct ccgcgtcttc aataaatacc atgtacagcg ccataatccc
     8101 tcactccgtt gtcataaatt taaagcacgc aaacaaccgt tcacgatcca gctctgccgt
     8161 tttgcgggcc tcgccggtct gtgggttcac gatttcatcc accgacagga ttgcccgctg
     8221 caccctgacc tgcgtcgccc ggtccgggca gatgtaccag atttcatcga tgccgttagc
     8281 tttgcggttg aacagatacc cggacaccac ttcctgatac cggcgacggc tcttgacggt
     8341 gcgctccacc tcaaacgcca ccgttttacc gtccagctcc gccagggcgt ccggcacttt
     8401 catgccttta agactcagac ggtgcagaat gcgccagccg gtggcccctc tggcttccat
     8461 atcaaggcgc agggattgca cggccagccg gtgcggcaga tgtgctgccg acacccttga
     8521 cggctgaaac ggaataacat ccgccagcgg ttcgtcctcg tcgaacgaga acgccacgcc
     8581 atgcggcgtc agcccccaca cgctgacctg acggccgtcc accggatatt tggtccggac
     8641 cagcagccct ttcgccacca ggctgtcgag gaagcggtag accggctgca ccgccgcaat
     8701 ccccagccgc cgcgcaacca gctccgccgt ggaacacagc tcttcccgca accagcgcag
     8761 ggtcagccgg gttttctccg cgttccgcgc ctgtcgtttc gcgtggctga cgttgtacag
     8821 ctccagcgcc atcagtaaat ccccgcaaaa tcatcatccg ctttcggccc gccgccgtcg
     8881 gccgggggcc ggaactccgc caggggatcg gttttcgcca gcaccgggaa acgctgcaac
     8941 gggatttccc ggcgctcaac ccgcagcgga ctgctgaacg ccatccgggc cacacccagc
     9001 ccggtcatga ccgcgaaccc gtccggcagg tgttgcaggg tgttcacgtc aaacagcggc
     9061 cgcgcctcct tctggatgaa gctgtccccg ctgatatgct ccacgttccc cgcctcccgg
     9121 ctggcacggc ggcgctccac gtccaccctg atttccccgg tctgccccgc cgcccactgc
     9181 gcggactcca ggctggccgc ccggtaaaac cagcggatcg gcgtgttatc cagtaccgtg
     9241 gttttcacaa attcagcggg cagatcctgc ccgcactgcc cgaaatcgcc cagc
//
