LOCUS       CP088745               18170 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain B16EC0942 plasmid pB16EC0942-1, complete
            sequence.
ACCESSION   CP088745
VERSION     CP088745.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391574
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18170)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18170)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 14:00:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,328
            CDSs (total)                      :: 5,194
            Genes (coding)                    :: 4,979
            CDSs (with protein)               :: 4,979
            Genes (RNA)                       :: 134
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 94
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 215
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 93 of 215
            Pseudo Genes (incomplete)         :: 139 of 215
            Pseudo Genes (internal stop)      :: 38 of 215
            Pseudo Genes (multiple problems)  :: 48 of 215
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18170
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="B16EC0942"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pB16EC0942-1"
                     /geo_loc_name="South Korea"
                     /lat_lon="37.68 N 126.77 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            37..434
                     /locus_tag="LQT46_24325"
                     /pseudo=""
     CDS             37..434
                     /locus_tag="LQT46_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail U family protein"
                     /name="phage minor tail U family protein"
     gene            442..1182
                     /locus_tag="LQT46_24330"
     CDS             442..1182
                     /locus_tag="LQT46_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="UGI93401.1"
                     /translation="MPVPNPTMPVKGAGTTLWVYKGSGDPYANPLSDVDWSRLAKVKDL
                     TPGELTAESYDDSYLDDKDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNEGD
                     TRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTAATG
                     MTVTPASTSVVKGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKGVAAG
                     KVNIPVVSGNGELAVVAEITVTAS"
                     /name="phage tail protein"
     gene            1136..1621
                     /locus_tag="LQT46_24335"
     CDS             1136..1621
                     /locus_tag="LQT46_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="UGI93402.1"
                     /translation="MVNLLWLQKSPSPPVNPESQRCFLKTESFEHNGVTVTLSELSALQ
                     RIEHLALMKRQAEQAESDSNRKFTVEDAIRTGAFLVAMSLWHNHPQKTQMPSMNEAVKQ
                     IEQEVLTTWPTEAISHAENVVYRLSGMYEFVVNNAPEQTEDAGPAEPVSAGKCSTVS"
                     /name="phage minor tail protein G"
     gene            1603..2038
                     /locus_tag="LQT46_24340"
                     /pseudo=""
     CDS             1603..2038
                     /locus_tag="LQT46_24340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /name="phage tail assembly protein T"
     gene            2031..4592
                     /locus_tag="LQT46_24345"
     CDS             2031..4592
                     /locus_tag="LQT46_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="UGI93403.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTETDAKKTAAVVE
                     QSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKDSF
                     GGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQSGLT
                     ADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGVEVDK
                     VAEAFGKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAATKGFD
                     DQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAFKKADDIWN
                     LRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQTQQDKNAQQQSDTEASRLKYTE
                     EAQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSG
                     VKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQFAVLEEAAQ
                     RRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAI
                     DAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQLRGSWMAGLKS
                     GWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILLK
                     QAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTGTGGKYEPAGIVHR
                     GEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQASGTFEQNNHVVINND
                     GTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSGGGR"
                     /name="phage tail tape measure protein"
     gene            4589..4918
                     /locus_tag="LQT46_24350"
     CDS             4589..4918
                     /locus_tag="LQT46_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="UGI93404.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTYS
                     VTLSVPREEATVLESFLEEHGGWKSFLWTPPYEWQQIKVTCAKWSSRVSMLRVEFSAEF
                     EQVVN"
                     /name="phage tail protein"
     gene            4918..5616
                     /locus_tag="LQT46_24355"
     CDS             4918..5616
                     /locus_tag="LQT46_24355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="UGI93405.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNEK
                     GEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVGGTVV
                     RRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDGAVF
                     PGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFG
                     GFLSINKLSQ"
                     /name="phage minor tail protein L"
     gene            5622..6365
                     /locus_tag="LQT46_24360"
     CDS             5622..6365
                     /locus_tag="LQT46_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="UGI93406.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVSTPEGERYFPCVNISGEPED
                     YFRMAPEDWLQAKMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGVIHKFR
                     CVPHLTGRRFEHGATDCYTLFRDAYHLAGIEMPDFHRGDDWWRNGQNLYLDNMEATGFY
                     RVALTEAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRRTHSL
                     WRHRAWRASAFTGIYNDLAAASTFV"
                     /name="C40 family peptidase"
     gene            6362..6934
                     /locus_tag="LQT46_24365"
     CDS             6362..6934
                     /locus_tag="LQT46_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="UGI93408.1"
                     /translation="MKTGAEAIRALATQLPAFRQKLCDGWYQVRIAGRDVSTSGLTAQL
                     HETLPDGAVIHIVPRVAGAKSGGVFQIVLGAAAIAGSFFTAGATLAAWGAAIGAGGMTG
                     ILFSLGASMVLGGVAQMLAPKARTPRTQTTDNGKQNTYFSSLDNMVAQGNVLPVLYGEM
                     RVGSRVVSQEISTADEGDGGQVVVIGR"
                     /name="tail assembly protein"
     gene            6995..10408
                     /locus_tag="LQT46_24370"
     CDS             6995..10408
                     /locus_tag="LQT46_24370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="UGI93407.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKSV
                     LLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITRTI
                     TSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTTSQY
                     LASVMVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALVGVQV
                     DSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTLKPAYSNNMAWCLWDMLT
                     HPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRKAWDVLS
                     DFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSALKDRHNAV
                     EVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLWLIKTELLE
                     TQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQIRTLTLDREITLPSSG
                     TTLISLVDGSGNPVSVEVQSVTDRVKVKVSRIPDGVAEYSVWGLKLPTLRQRLFRCVSI
                     RENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHLTAEVTADSGEY
                     QVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFRQLALGRYTLTVRA
                     VNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTVQFEFWFSETRI
                     ADIRQVETTARYLGTGLYWIAASINIKPGHDYYFYIRSVNTVGKSAFVEAVGRASDDAE
                     GYLDFFKGKITESHLGKELLEKVDLTEDNASRLDEFSKEWKDANDKWNAMWGVKIEQTK
                     DGKHYVAGIGLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFL
                     KRLTAPTITSGGSPPVFSLTSDGKLTAKNADISGSVNANSGTLNNVTINQNCTIKGMLE
                     ATQVRGDFVKAVSKAFPKKVGTWGNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAY
                     DDPGSGNNPGGTRYTGYGFEVRKNGVLIASRETKGAIPGSYSAVIDMPSGGGSVTLEFK
                     IFQKGNQGAGNITDCTVIVTKKAASGISIR"
                     /name="host specificity protein J"
     gene            10479..11078
                     /locus_tag="LQT46_24375"
     CDS             10479..11078
                     /locus_tag="LQT46_24375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="UGI93395.1"
                     /translation="MRKVCAAILSAAICLVVSGAPAWASEHQSTLSAGYLHASTNVPGS
                     DDLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAGPS
                     VRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDEGRHSNTSLAWGAG
                     VQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF"
                     /name="Ail/Lom family outer membrane beta-barrel protein"
     gene            11143..14103
                     /locus_tag="LQT46_24380"
     CDS             11143..14103
                     /locus_tag="LQT46_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="UGI93396.1"
                     /translation="MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPDE
                     AGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSQPGTLNDFLGAMTEDDARPEALR
                     RFELMVEEVARNASAVAQNTAEAKKSASDASTSAREAATHATDAAGSARAASTSAGQAA
                     TSAQSASSSAGTASAKATEASKSAAAAESSKSAAATSAGAAKTSETNAAASQQSAATSA
                     STATTKASEAATSARDASASKEAAKSSETNAASSASSAASSATAAGNSAKAAKTSETNA
                     KASETAAEQSASAAAGSKTAAASSASAASTSAGQASASATAAGKSAESAASSASTATTK
                     AGEAAEQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSAASSASSASASKDE
                     ATRQASAAKGSATTASTKAKEAAGSATAAAQSKSTAESAATRAETAAKRAEDIASAVAL
                     EDASTTKKGIVQLSSATNSTSESLAATPKAVKAAYDLANGKYTAQDATTAQKGIVQLSS
                     ATNSTSEMLAATPKSVKAAYDLANGKYTAQDATTAQKGIVQLSSATNSASETLAATPKA
                     VKAANDNANGRVPSARKVNGKALSADITLTPKDIGTLNSTTMSFSGGAGWFKLATVTMP
                     QASSVVSITLIGGAGFNVGSPQQAGISELVLRAGNGNPKGITGALWQRTSTGFTNFAWV
                     NTSGDTYDIYVAIGNYATGVNIQWDYTSNASVTIHTSPAYSANKPEGLTDGTVYSLYTP
                     SEQFYPPGAPIPWPSDTVPSGYALMQGQTFDKSAYPKLAAAYPSGVIPDMRGWTIKGKP
                     ASGRAVLSQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKSTNNTGAHTHSLSGSTNA
                     AGNHSHRDGRRFNPSVFKDTYQYGYTSSGQNTWGVQGSVGMSTGWLANTSTDGNHSHSL
                     SGTAASAGAHAHTVGIGAHTHSVAIGSHGHTITVNAAGNAENTVKNIAFNYIVRLA"
                     /name="prophage tail fiber N-terminal domain-containing
                     protein"
     gene            14100..14990
                     /locus_tag="LQT46_24385"
     CDS             14100..14990
                     /locus_tag="LQT46_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macro domain-containing protein"
                     /protein_id="UGI93397.1"
                     /translation="MITLILSAPVTEMAEAFKRVFANADNVNIVGKPFETIREFDCMVS
                     AANSFGLMDGGVDAAITAFFGTQLQSRVQNHILREYLGEQPVGSAFVIETGHNHHPWLV
                     HAPTMRVPLTIDGTDAVYNATWAALLAIFQHNKNATTDRKIKTVVFPAMGAGCGQVPFE
                     SVARQMKQAWDNFNKKTESINWEYAHSRQSAVFGTYAYCPGNSVCRYADTKYIGCGDYR
                     TYCSRSGQFCISHVHQADDVLTNNRSRPDSHTHRFNPENPVGNLTSGAHSHGSSIVIGA
                     PTHTLNKQYSVSDIK"
                     /name="macro domain-containing protein"
     gene            14999..15574
                     /locus_tag="LQT46_24390"
     CDS             14999..15574
                     /locus_tag="LQT46_24390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="UGI93398.1"
                     /translation="MDFRMTEQPRTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTDI
                     APPDIPAGFVAVFNGDDASWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSPEG
                     EYQKWNGTAWVKDAEAEKLFRIREAEETKNSLMQVASEHIAPLQDAADLEIATEEETSL
                     LEAWKKYRVLLNRVDTSLSPDIEWPSQP"
                     /name="tail fiber assembly protein"
     gene            complement(15607..16572)
                     /locus_tag="LQT46_24395"
     CDS             complement(15607..16572)
                     /locus_tag="LQT46_24395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001728175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition protein"
                     /protein_id="UGI93399.1"
                     /translation="MKQRSLLKNAPDINRIMSNNHHAPEHQPVSPMVGDLKRQLSSLTG
                     NSITLPVCGRNVNFKLETIPADKVEMATMVWLGNERDQDLLNESSLADLIPSFLTSGQQ
                     NPAFARKVSGIVEVADGSRRRKAAILTGCDYRVLIGDLDDEQMHWLSQIGNDYRPISAY
                     ERGKRYLRKLNDFDGNVKALAEAENIDRNIITRCINTAGLPKDILAIFNHPGELSARAG
                     DSLFKVYKKNMAAMSNAAHHLLAIKKNGEDLEASRIIQILSDSVLVGGEEKTKDEKKYG
                     EGITARYKGNFVTIKIDSRKISKEILSRIELLLEEQSTDN"
                     /name="ParB/RepB/Spo0J family plasmid partition protein"
     gene            complement(16572..17738)
                     /gene="sopA"
                     /locus_tag="LQT46_24400"
     CDS             complement(16572..17738)
                     /gene="sopA"
                     /locus_tag="LQT46_24400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="UGI93400.1"
                     /translation="MSLKKLLQDCVTRGQEMTQAIAIAQFGDDSPEARRITRRWGITEV
                     ADLIGVTPQAIRDAEKSGRLPAPDFEMRGRIERRAGYTIDQINSMRAVFGNPNQRPQDK
                     NPVVLAVMSHKGGVYKTSSAVHQAQWLALQGHRVLLVEGNDPQGTASMYHGYVPDLHIH
                     AEDTLLPFYLGERDNAEYAIKPTCWPGLDIIPSCLALHRIETDLMQYHAQGKLPHPPHL
                     MLRAAIESVWDNYDVIVIDSAPNLGTGTINVVCAADVIVVATPAELFDYASVLQFFTML
                     LDLLESVDLGGFEPTVRLLLTKYSLTTGNQSRWMEEQIRNTWGSMVLRQVVRVTDEVGK
                     GQIKMRTVFEQAANQRSTLNAWRNAVSIWDPVCREIFDDLIKPRWENE"
                     /name="sopA"
ORIGIN
        1 tgcgctgcag catcaactga gaatggtaat aaagcgatga aacatactga actccgtgca
       61 gccgtactgg atgcactgga gaagcatgac accggggcga cgctttttga tggtcgcccc
      121 gctgtttttg atgaggcgga ttttccggca attgccggtt tatctcaccg gcgctgaata
      181 cacgggcgaa gagctggaca gtgatacctg gcaggcggag ctgcatattg aagttttcct
      241 gcctgctcag gtgccggatt cagagctgga ttcgtggatg gagtcccgga tttatccggt
      301 gatgagcgat gtcccggcac tgtcagattt gatcaccagt atggtggcca gtggctatga
      361 cttaccggcg cgacgatgat gcgggcctgt ggagttcagc cgatctgact tatgtcatta
      421 cctatgaaat gtgaggacgc tatgcctgta ccaaatccta caatgccggt gaaaggtgcc
      481 gggaccaccc tgtgggttta taaggggagc ggtgaccctt atgcgaaccc gctttcagac
      541 gttgactggt cgcgtctggc aaaagttaaa gacctgacgc ccggcgaact gaccgctgag
      601 tcctatgacg acagctatct cgatgataaa gatgcagact ggactgcgac cgggcagggg
      661 cagaaatctg ccggagatac cagcttcacg ctggcgtgga tgcccggaga gcaggggcag
      721 caggcgctgc tggcgtggtt taatgaaggt gatacccgtg cctataaaat ccgcttcccg
      781 aacggcacgg tcgatgtgtt ccgtggctgg gtcagcagta tcggtaaggc ggtgacggcg
      841 aaggaagtga ttacccgcac ggtgaaggtc accaatgtgg gacgtccgtc gatggcagaa
      901 gatcgcagca cggtaacagc ggcaaccggt atgactgtga cgcctgccag cacttcggtg
      961 gtgaaagggc agagcaccac gctgaccgtg gcattccagc cggaaggcgc aaccgacaag
     1021 agcttccgtg cggtgtctgc ggataaaaca aaagccaccg tgtcggtcag tggtatgacc
     1081 atcaccgtga aaggtgttgc tgcaggcaag gtcaacattc cggttgtatc cggtaatggt
     1141 gaacttgctg tggttgcaga aatcaccgtc accgccagtt aatccggaga gtcagcgatg
     1201 tttcctgaaa accgaatcat ttgaacataa cggtgtgacc gtcacgcttt ctgaactgtc
     1261 agccctgcag cgtattgagc atctcgccct gatgaaacgg caggcagaac aggcggagtc
     1321 agacagcaac cggaagttta ctgtggaaga cgccatcaga accggcgcgt ttctggtggc
     1381 gatgtccctg tggcataacc atccgcagaa gacgcagatg ccgtccatga atgaagccgt
     1441 taaacagatt gagcaggaag tgcttaccac ctggcccacg gaggcaattt ctcatgctga
     1501 aaacgtggtg taccggctgt ctggtatgta tgagtttgtg gtgaataatg cccctgaaca
     1561 gacagaggac gccgggcccg cagagcctgt ttctgcggga aagtgttcga cggtgagctg
     1621 agttttgccc tgaaactggc gcgtgagatg gggcgacccg actggcgtgc catgcttgcc
     1681 ggggatgtca tccacggagt atgccgactg gcaccgcttt tacagtaccc attattttca
     1741 tgatgttctg ctggatatgc acttttccgg gctgacgtac accgtgctca gcctgttttt
     1801 cagcgatccg gatatgcatc cgctggattt cagtctgctg aaccggcgcg aggctgacga
     1861 agagcctgaa gatgatgtgc tgatgcagaa agcggcaggg cttgccggag gtgtccgctt
     1921 tggcccggac gggaatgaag ttatccctac ttccccggat gtggcggaca tgacggagga
     1981 tgacgtaatg ctgatgacag tatcagaagg gatcgcagga ggagtccggt atggctgaac
     2041 cggtaggcga tctggtcgtt gatttaagtc tggatgcggc cagatttgac gagcagatgg
     2101 ccagagtcag gcgtcatttt tccggtacgg aaactgatgc gaaaaaaaca gcggcagtcg
     2161 ttgaacagtc gctgagccga caggcgctgg ctgcacagaa agcggggatt tccgtcgggc
     2221 agtataaagc cgccatgcgt atgctgcctg cacagttcac cgacgtggcc acgcagcttg
     2281 caggcgggca aagcccgtgg ctgatcctgc tgcaacaggg tggtcaggtt aaggactcct
     2341 tcggcgggat gatccccatg ttccgggggc ttgccggtgc gatcaccctg ccgatggtcg
     2401 gggctacctc gctggcggtg gcgaccggtg cgctggcgta tgcctggtat cagggtaact
     2461 caaccctgtc cgatttcaac aaaacgctgg tcctttccgg taatcagtcg ggtctgacgg
     2521 cagatcgtat gctggtcctg tccagagccg ggcaggcggc agggctgacg tttaaccaga
     2581 ccagcgagtc actcagtgca ctggttaagg cgggggtaag cggtgaggct cagattgcgt
     2641 ccatcagcca gagtgtggcg cgtttctctt ctgcatccgg tgtggaggtg gacaaggtcg
     2701 ctgaagcctt cgggaagctg accactgacc cgacgtcggg gctgacggcg atggcgcgcc
     2761 agttccataa cgtgacggcg gagcagattg cgtatgttgc tcagttgcag cgttccggcg
     2821 atgaagccgg ggcattgcag gcggcgaacg aagccgcaac gaaagggttt gatgaccaga
     2881 cccgccgcct gaaagagaac atgggcacgc tggagacctg ggcagacagg acagcgcggg
     2941 cattcaaatc catgtgggat gcggtgctgg atattggtcg tcctgatacc gcgcaggaga
     3001 tgctgattaa ggcagaggct gcgtttaaga aagcagacga catctggaat ctgcgcaagg
     3061 atgattattt tgttaacgat gaagcgcggg cgcgttactg ggatgatcgt gaaaaggccc
     3121 gtcttgcgct tgaagccgcc cgaaagaagg ctgagcagca gactcaacag gacaaaaatg
     3181 cgcagcagca gagcgatacc gaagcgtcac ggctgaaata taccgaagag gcgcagaagg
     3241 cttacgaacg gctgcagacg ccgctggaga aatataccgc ccgtcaggaa gaactgaaca
     3301 aggcactgaa agacgggaaa atcctgcagg cggattacaa cacgctgatg gcggcggcga
     3361 aaaaggatta tgaagcgacg ctgaaaaagc cgaaacagtc cggcgtgaag gtgtctgcgg
     3421 gcgatcgtca ggaagacagt gctcatgctg ccctgctgac gcttcaggca gaactccgga
     3481 cgctggagaa gcatgccgga gcgaatgaga aaatcagcca gcagcgccgg gatttgtgga
     3541 aggcggagag tcagttcgcg gtactggagg aggcggcgca acgtcgccag ctgtctgcac
     3601 aggagaaatc cctgctggcg cataaagatg agacgctgga gtacaaacgc cagctggctg
     3661 cacttggcga caaggttacg tatcaggagc gcctgaacgc gctggcgcag caggcggata
     3721 aattcgcaca gcagcaacgg gcaaaacggg ccgccattga tgcgaaaagc cgggggctga
     3781 ctgaccggca ggcagaacgg gaagccacgg aacagcgcct gaaggaacag tatggcgata
     3841 atccgctggc gctgaataac gtcatgtcag agcagaaaaa gacctgggcg gctgaagacc
     3901 agcttcgcgg gagctggatg gcaggcctga agtccggctg gagtgagtgg gaagagagcg
     3961 ccacggacag tatgtcgcag gttaaaagtg cagccacgca gacctttgat ggtattgcac
     4021 agaatatggc ggcgatgctg accggcagtg agcagaactg gcgcagcttc acccgttccg
     4081 tgctgtccat gatgacagaa attctgctta agcaggcaat ggtggggatt gtcgggagta
     4141 tcggcagcgc cattggcggg gctgttggtg gcggcgcatc cgcgtcaggc ggtacagcca
     4201 ttcaggccgc tgcggcgaaa ttccattttg caaccggagg atttacggga accggcggca
     4261 aatatgagcc agcggggatt gttcaccgtg gtgaatttgt cttcacgaag gaggcaacca
     4321 gccggattgg cgtggggaat ctttaccggc tgatgcgcgg ctatgccacc ggcggttatg
     4381 tcggtacacc gggcagcatg gcagacagcc ggtcgcaggc gtccgggacg tttgagcaga
     4441 ataaccatgt ggtgattaac aacgacggca cgaacgggca gataggtccg gctgctctga
     4501 aggcggtgta tgacatggcc cgcaagggtg cccgtgatga aattcagaca cagatgcgtg
     4561 atggtggcct gttctccgga ggtggacgat gaagaccttc cgctggaaag tgaaacccgg
     4621 tatggatgtg gcttcggtcc cttctgtaag aaaggtgcgc tttggtgatg gctattctca
     4681 gcgagcgcct gccgggctga atgccaacct gaaaacgtac agcgtgacgc tttctgtccc
     4741 ccgtgaggag gccacggtac tggagtcgtt tctggaagag cacgggggct ggaaatcctt
     4801 tctgtggacg ccgccttatg agtggcagca gataaaggtg acctgcgcaa aatggtcgtc
     4861 gcgggtcagt atgctgcgtg ttgagttcag cgcagagttt gaacaggtgg tgaactgatg
     4921 caggatatcc ggcaggaaac actgaatgaa tgcacccgtg cggagcagtc ggccagcgtg
     4981 gtgctctggg aaatcgacct gacagaggtc ggtggagaac gttatttttt ctgtaatgag
     5041 cagaacgaaa aaggtgagcc ggtcacctgg caggggcgac agtatcagcc gtatcccatt
     5101 caggggagcg gttttgaact gaatggcaaa ggcaccagta cgcgccccac gctgacggtt
     5161 tctaacctgt acggtatggt caccgggatg gcggaagata tgcagagtct ggtcggcgga
     5221 acggtggtcc ggcgtaaggt ttacgcccgt tttctggatg cggtgaactt cgtcaacgga
     5281 aacagttacg ccgatccgga gcaggaggtg atcagccgct ggcgcattga gcagtgcagc
     5341 gaactgagcg cggtgagtgc ctcctttgta ctgtccacgc cgacggaaac ggatggcgct
     5401 gtttttccgg gacgtatcat gctggccaac acctgcacct ggacctatcg cggtgacgag
     5461 tgcggttata gcggtccggc tgtcgcggat gaatatgacc agccaacgtc cgatatcacg
     5521 aaggataaat gcagcaaatg cctgagcggt tgtaagtttc gcaataacgt cggcaacttt
     5581 ggcggcttcc tttccattaa caaactttcg cagtaaatcc catgacacag acagaatcag
     5641 cgattctggc gcacgcccgg cgatgtgcgc cagcggagtc gtgcggcttc gtggtaagca
     5701 cgccggaggg ggaaagatat ttcccctgcg tgaatatttc cggtgagccg gaggattatt
     5761 tccggatggc tccggaggac tggctgcagg ccaaaatgca gggtgagatt gtggcgctgg
     5821 tccacagtca ccccggtggt ctgccctggc tgagtgaggc cgaccggcgg ctgcaggtgc
     5881 agagtgattt gccgtggtgg ctggtctgcc ggggagtgat tcataagttc cgctgtgtgc
     5941 cgcatctcac cgggcggcgc tttgagcacg gggcgacgga ctgttacacg ctgttccggg
     6001 atgcttatca tctggctggg attgagatgc cggattttca tcgcggggat gactggtggc
     6061 gtaacggtca gaatctctat cttgacaata tggaggcgac tggtttttac cgtgtcgcac
     6121 tgacagaggc gcagccgggc gatgtgctgc tgtgctgctt tggttcatcg gtgccgaatc
     6181 atgccgctat ttactgcggt gacggcgagc tgctgcacca tattcctgaa caactgagca
     6241 aacgagagag gtataccgac aaatggcagc gacgcacaca ctccctctgg cgtcaccggg
     6301 catggcgcgc atctgccttt acggggattt acaacgattt ggccgccgca tcgaccttcg
     6361 tgtgaaaacg ggggctgaag ccatccgggc actggccaca cagctcccgg cgtttcgtca
     6421 gaaactgtgc gacggctggt atcaggtacg gattgccggg cgggacgtca gcacgtccgg
     6481 gttaacggcg cagttacatg agactctgcc tgatggcgct gtgattcata ttgttcccag
     6541 agtcgccggg gccaagtcag gtggcgtatt ccagattgtc ctgggagctg ccgccattgc
     6601 cggatcattc tttactgccg gagccaccct tgcagcatgg ggggcagcca ttggggccgg
     6661 tggtatgacc ggcatcctgt tttctctcgg tgccagtatg gtgctcggtg gtgtggcgca
     6721 gatgctggca ccgaaagcca gaactccccg tacacagaca acggataacg gcaaacagaa
     6781 cacctatttc tcctcactgg ataacatggt tgctcagggc aatgttttgc ctgttctgta
     6841 cggtgaaatg cgtgtggggt cacgggtggt ttctcaggag atcagcacgg cagacgaagg
     6901 ggacggtggt caggttgtgg tgattggtcg ctgatgcaaa atgttttatg tgaaaccgcc
     6961 tgcgggcggt tttgtcgttt atggagcgtg aggaatgggt aaaggcagca gtaaggggca
     7021 taccccgcgc gaagcgaaag ataacctgaa atccacgcag ttactgagtg tgattgatgc
     7081 catcagcgaa gggccggttg aaggtccggt ggatggatta aaaagcgtgc tgctgaacag
     7141 tacgccggtg ctggacagtg aggggaatac caacatctcc ggcgtcacgg tggtgttccg
     7201 ggcaggtgag caggagcaga caccgccgga aggttttgaa tcctccggct ccgagactgt
     7261 gctgggtacg gaagtgaaat atgacacgcc gatcacccgg accatcacgt cggcaaacat
     7321 tgaccgtctg cgttttactt tcggcgtgca ggcactggtg gaaaccacct caaagggtga
     7381 ccggaatccg tcggaagtcc gcctgctggt tcagatacag cgtaacggtg gctgggtgac
     7441 ggaaaaagac atcaccatta agggcaaaac cacctcgcag tatctggcct cggtgatggt
     7501 ggataacctg cctccgcgcc cgttcaatat ccggatgcgc aggatgacac cggacagcac
     7561 tacagaccag ctgcagaaca aaacgctctg gtcgtcatac accgaaatca tcgatgtgaa
     7621 acagtgctac ccgaacacgg cactggtcgg cgtacaggtg gattcggagc agttcggcag
     7681 ccagcaggtg agtcgtaatt atcatcttcg cgggcgcatt ctgcaggtgc cgtcgaacta
     7741 taacccgcag acgcgacaat acagcggtat ctgggacgga acgttaaaac cggcatacag
     7801 caacaacatg gcctggtgtc tgtgggatat gctgacccac ccgcgctacg gcatggggaa
     7861 gcgtcttggt gcggcggatg tggacaaatg ggcgctgtat gtcatcggcc agtactgcga
     7921 ccagtcagtg ccggacggct ttggcggcac ggagccgcgc atcacctgta atgcgtacct
     7981 gaccacacag cgcaaggcgt gggatgtgct cagtgatttc tgctcggcga tgcgctgtat
     8041 gccggtatgg aacgggcaga cgctgacgtt cgtgcaggac cgaccgtcgg ataaggtgtg
     8101 gacctataac cgcagtaatg tggtgatgcc ggatgatggc gcgccgttcc gctacagctt
     8161 tagcgccctg aaagaccgcc ataatgccgt tgaggtgaac tggattgacc cggataacgg
     8221 ctgggagacg gcgacagagc ttgtggagga tacgcaggcc attgcccgtt acggtcgtaa
     8281 cgtcacgaag atggatgctt ttggctgtac cagccggggg caggcacacc gcgccgggct
     8341 gtggctgatt aaaacagaac tgctggaaac gcagaccgtg gacttcagcg tgggcgcaga
     8401 agggcttcgc catgtgccgg gcgatgtcat tgaaatctgt gatgatgact atgccggtat
     8461 cagcaccggc gggcgcgtgc tggcggtaaa cagccagatc cggacgctga cgcttgaccg
     8521 tgaaatcact ctgccatcct ccggtaccac gctgataagc ctggttgacg gaagtggtaa
     8581 tccggtcagc gtggaggttc agtccgtcac cgaccgcgtg aaggtgaaag tgagccgtat
     8641 tcctgacggc gttgctgaat acagcgtgtg ggggctgaag ctgccgacgc tgcgccagcg
     8701 cctgttccgc tgcgtgagta tccgtgagaa cgacgacggc acgtatgcca tcaccgccgt
     8761 gcagcatgta ccggaaaaag aggccatcgt ggataacggg gcgcactttg acggcgacca
     8821 gagcggcacg gtgaatggtg tcacgccgcc agcggtgcag cacctgaccg ccgaagtcac
     8881 cgcagacagc ggggaatatc aggtgctggc gcgctgggac acgccgaagg tggtgaaggg
     8941 cgtgagcttc ctgctccgtc tgaccgtaac agcggatgac ggcagtgagc ggctggtcag
     9001 cacggcccgg acgacggaaa ccacataccg cttcaggcaa ctggcgctgg ggcgttacac
     9061 gctgacggtc cgggcggtaa atgcgtgggg acagcagggc gatccggcat cggtatcgtt
     9121 ccggattgcc gccccggcag cgccgtcgcg gattgagctg acgccgggct attttcagat
     9181 aactgccacg ccgcatcttg cggtttatga tccgacggta cagtttgagt tctggttctc
     9241 ggaaacgcgg attgccgata tcaggcaggt tgaaaccaca gcccgctacc ttggcacggg
     9301 gctgtactgg atagccgcca gtatcaatat caaaccgggc catgattatt acttttatat
     9361 ccgcagtgtg aacaccgttg gcaaatcggc attcgtggag gccgtcggtc gggcgagcga
     9421 tgatgcggaa ggttacctgg attttttcaa aggcaagata accgaatctc atctcggcaa
     9481 ggagctgctg gaaaaagtcg atctgacgga ggataacgcc agcagactgg atgagttttc
     9541 gaaagagtgg aaggacgcta acgataaatg gaatgccatg tggggcgtca aaattgagca
     9601 gaccaaagac ggcaaacatt atgtcgcggg tattggcctc agcatggagg acacggagga
     9661 aggcaagctg agccagtttc tggttgccgc taaccgtatc gcgtttattg acccggcaaa
     9721 cgggaatgaa acgccgatgt ttgtggcgca gggcaaccag atattcatga acgacgtgtt
     9781 cctgaagcgc ctgacggccc ccaccattac cagcggtggc agtcctccgg tattttccct
     9841 gacatcagac ggaaagctga ccgctaaaaa tgcggatatc agtggcagtg tgaatgcgaa
     9901 ctcaggaacg ctcaacaatg tcacgattaa ccagaactgt acgattaagg gcatgctgga
     9961 ggcgacccag gtcagagggg atttcgttaa agctgtatca aaagccttcc cgaaaaaagt
    10021 cggtacgtgg ggtaacacgg aaacaccaaa cggtacggtt acagtcacca tcagcgatga
    10081 tcataacttt gaccgccaga ttattattcc gcccattatt tttaacggta tagcgtatga
    10141 cgatccgggg agcggaaata acccaggagg cacgcgatac acgggttatg gttttgaagt
    10201 tcgcaaaaac ggcgtattaa tcgcatccag agaaactaaa ggggccattc ccggtagtta
    10261 cagtgcagtt attgatatgc ctagtggtgg tggtagcgtc actctggagt ttaagatttt
    10321 ccagaaaggc aatcaggggg caggcaatat caccgactgt acggtgattg tgaccaaaaa
    10381 agctgcttcc ggcatcagta ttcgttgaaa tatttataac cccaataaag ggcgtcagga
    10441 atgacgcctt ttttattgca gaaaagcgag aggtaattat gcgtaaagtt tgtgcagcaa
    10501 ttttgtccgc agccatttgt ctggtcgtat ccggtgcgcc tgcatgggcg tctgaacatc
    10561 agtccacgct gagcgcgggg tatcttcatg cctcgacgaa cgttcccggc agtgatgatc
    10621 tgaacgggat taacgtgaaa taccgttatg agtttacgga cacactgggg ctggtgacgt
    10681 cattcagcta tgcaggagac aagaatcgcc agctgacccg ttacagcgat acccgctggc
    10741 atgaagattc cgttcgtaac cgctggttca gcgtaatggc ggggccgtct gtgcgcgtga
    10801 atgaatggtt cagcgcgtat gcgatggcgg gtgtggctta cagccgtgtg tcgactttct
    10861 ccggggatta tcttcgcgta actgacaaca aggggaaaac gcacgatgtg ctgaccggaa
    10921 gtgatgaagg tcgccacagc aacacgtctc tggcgtgggg agctggcgtg cagtttaacc
    10981 cgaccgaatc cgtggccatt gatattgctt atgaaggctc cggcagtggc gactggcgca
    11041 ctgacggttt catcgtgggt gtcggttata agttctgatt agccaggtaa cacagtgtta
    11101 tgacagcccg ccggttcagg cgggcttttt tgtggggtga atatggcagt aaagatttca
    11161 ggtgtactga aagacggcac aggaaaaccg gtacagaact gcacaatcca gctgaaagca
    11221 aaacgtaaca gcaccacggt ggtggtgaac acgctggcct cagaaaatcc ggatgaagcc
    11281 gggcgttaca gcatggacgt tgagtacggt cagtacagcg ttattctgtt ggtggaggga
    11341 ttcccgccgt cacatgccgg gaccatcacc gtgtatgaag attctcaacc cggtacgctg
    11401 aatgattttc tcggtgccat gacggaggat gatgcccgtc cggaggcact gcgccgtttt
    11461 gaactgatgg tggaagaggt ggcgcgtaac gcgtccgcgg tggcacagaa cacagcagaa
    11521 gcgaagaagt cagccagcga tgccagcaca tcagcccgtg aggcggcaac ccatgcgact
    11581 gatgctgcag gctcagcacg cgcagccagc acgtcagccg gacaggccgc gacgtcggct
    11641 cagtcagcgt cttccagcgc aggaacggca tcagcaaagg ccactgaagc atcaaaaagt
    11701 gctgccgctg cagagtcctc aaaaagcgcg gcggctacca gtgccggtgc ggcgaaaacg
    11761 tcagaaacga atgcggcagc gtcacaacaa tcagcagcca cttctgcatc caccgcgacc
    11821 acgaaagcgt cagaagcagc cacttcagca cgggatgcgt cggcttcaaa agaggcggca
    11881 aaatcatcag aaacgaacgc agcctcgagc gccagcagcg cagcttcctc ggctacggcg
    11941 gcaggaaatt ccgcgaaggc ggcaaaaacg tccgagacga acgccaaggc ttctgaaacg
    12001 gcagcggaac agagtgcctc cgcagcagca ggctcaaaaa cagcggctgc gtcgtctgcc
    12061 agtgcagcgt caacaagtgc cgggcaggcc tcagccagtg ccactgccgc cggaaaatcg
    12121 gcagaaagcg ctgcatcgtc cgcttcaaca gctacaacga aggctggcga agccgctgaa
    12181 caggccagcg cagcagcgag gtctgcttcc gcagcgaaga catccgaaac gaacgcgaaa
    12241 gcgtcggaaa ccagcgcaga atcctcaaaa acggctgccg catcgtcagc cagttcggca
    12301 gcgtcatcgg catcatctgc gtctgcttca aaagatgagg cgaccagaca ggcgtcagca
    12361 gcgaagggca gcgccacgac ggcatccacg aaggcgaaag aggctgctgg cagtgcgaca
    12421 gcggcagcac agagcaaaag tacggcagaa tccgcagcaa cgcgcgctga gacagcggca
    12481 aaacgggcag aggatattgc atccgccgtg gcgcttgagg atgcgagcac gacgaaaaag
    12541 ggaatagtac agctcagtag tgcgactaac agcacttccg agtcactggc ggcaacacca
    12601 aaagccgtta aggccgcgta tgacctggct aacgggaaat acaccgcaca ggatgcaacg
    12661 acagcacaga aagggatcgt tcagctcagc agcgcgacca acagcacatc tgaaatgctg
    12721 gcggcaacgc caaagtcggt aaaggcagcc tatgaccttg ctaacgggaa atataccgct
    12781 caggacgcta cgacagcaca aaaaggaatt gtccagctca gtagtgcaac caacagcgca
    12841 tctgaaacgc ttgccgcgac accgaaagca gtgaaagcag ctaatgataa tgcgaatggt
    12901 cgggtacctt ctgcccgtaa ggtgaatggt aaggcgcttt cagcggatat aacactgacg
    12961 ccgaaagata ttggtacgct taactcaaca acaatgtcat tcagcggtgg tgctggttgg
    13021 ttcaaattag caacggtaac catgccacag gcgagttctg ttgtttcaat tacgttgatt
    13081 ggtggcgcgg gatttaacgt ggggtcacct caacaggcag gtatatctga acttgttttg
    13141 cgtgcaggta atggtaatcc gaaggggatt actggtgctt tatggcagcg cacatcgaca
    13201 gggtttacaa attttgcctg ggtcaataca tctggtgata cttacgatat ttacgttgca
    13261 atcggaaatt atgcgactgg tgtaaatatt caatgggatt ataccagtaa tgccagcgtg
    13321 acgattcata cgtcaccagc atattctgct aataagccgg aagggttaac ggacggtaca
    13381 gtttattcac tctatacgcc atcagagcag ttttatccgc ctggcgcacc aatcccgtgg
    13441 ccatcagata ccgttccgtc tggctatgcc ctgatgcagg ggcagacttt tgacaaatct
    13501 gcatacccga aacttgcagc cgcttatccg tcaggcgtga tccctgatat gcgtggctgg
    13561 acgattaagg gcaaacctgc cagtggtcgg gccgtattgt ctcaggaaca ggacggcatt
    13621 aaatcgcaca cccacagcgc cagcgcatcc agtacggatt tggggacgaa aaccacatcg
    13681 tcgtttgatt acggcactaa atccacgaat aacactggtg cgcataccca tagtttaagt
    13741 ggtagcacga atgcagctgg taatcacagc catagagatg gccgtcgatt taaccccagt
    13801 gtttttaaag atacttatca atatggttat acaagctcag gtcaaaatac ctggggtgta
    13861 caaggctcag taggtatgtc tacggggtgg ttagctaata ccagtacaga tggtaatcat
    13921 agccactcac tgtccggcac agcagcatct gcaggtgcac acgcacatac tgtcggtatt
    13981 ggtgcacaca cgcactccgt tgcgattggt tcacatggac ataccatcac cgttaacgct
    14041 gctggtaacg cggaaaacac cgtcaaaaac atcgcattta actatattgt gaggcttgca
    14101 tgattacgct cattctttct gcaccagtaa cagaaatggc tgaagcattt aagcgggtat
    14161 ttgcaaacgc agataatgtg aatattgtcg gaaagccatt tgaaacaatc agagaatttg
    14221 actgcatggt aagtgcggca aatagtttcg gcctgatgga tggcggcgtt gatgccgcca
    14281 ttaccgcatt cttcggtact cagttacagt cccgcgttca gaatcatatt cttcgtgaat
    14341 atctaggcga acagcctgta ggttctgcat ttgtaattga aacggggcat aatcatcacc
    14401 cctggctggt acatgcgcca acaatgcgtg ttccgctgac aattgacgga acagacgctg
    14461 tatataatgc aacctgggcc gctctgcttg ccatctttca gcacaataaa aacgcaacga
    14521 cagacaggaa aataaagacg gtggtattcc ctgcaatggg ggccggatgt ggtcaggttc
    14581 cgtttgaaag cgttgcccgg caaatgaagc aggcatggga taactttaat aagaaaacag
    14641 aatcaattaa ctgggaatac gcacactccc gccagtcggc agtatttggc acatatgcat
    14701 actgtccggg taattctgtt tgccgttatg cggatactaa atatattgga tgcggcgatt
    14761 atcggacgta ttgctcacgt tccgggcagt tctgtattag ccatgtgcat caggccgatg
    14821 acgtgctgac taataatcgc tctcgccctg attcgcatac acaccggttt aatccagaaa
    14881 atcccgtagg caatctcacc tctggcgcac atagccacgg aagtagcatc gttattggtg
    14941 ctcccaccca tacgctcaat aaacaatatt ctgtctctga tattaagtag aggtgaacat
    15001 ggattttaga atgactgaac aaccacggac cataaaaatt tataatctgc tggccggaac
    15061 taatgaattt attggtgaag gtgatgcata cattccacct catacaggtc tacctgcaaa
    15121 cagtaccgat attgcaccgc cagatattcc ggcaggcttc gtggctgttt tcaacggtga
    15181 tgatgcatcg tggcatctcg ttgaagatca tcggggtaaa acggtttatg acgtggcatc
    15241 aggggacgcg ttatttattt ctgaactcgg tccgttaccg gaaaatgtta cttggttgtc
    15301 gccggaaggg gaatatcaga agtggaacgg tacagcctgg gtgaaagatg cagaagcaga
    15361 aaaactattc cggatccggg aggcggaaga aacaaaaaac agcctgatgc aggtagccag
    15421 tgagcatatt gcgccgcttc aggatgctgc agatctggaa atcgcaacgg aggaagaaac
    15481 ctcgttgctg gaagcctgga aaaagtatcg ggtgttgctg aaccgtgttg atacatcact
    15541 atctccagat atcgagtggc caagtcaacc ataaatcaat atcccctgca atgcagggga
    15601 tagttcttaa ttatcagtag attgttcctc tagtaacaac tcaattctgc ttagtatttc
    15661 tttagatatt ttgcggctat caatttttat agttacaaaa ttacctttat atctggccgt
    15721 gatcccttcc ccatattttt tctcgtcttt tgttttttcc tcgccgccaa ccagaacaga
    15781 gtcagataat atttgtataa tccgtgaagc ttctaaatcc tcgccgtttt ttttaattgc
    15841 cagaagatga tgagcagcat tgctcatggc agccatgttt tttttgtaaa ccttaaacaa
    15901 agaatctcca gcacgagctg acagttctcc tggatgattg aagatagcta atatatcttt
    15961 tggtagacca gctgtattaa tacagcgagt gataatattt ctatctatat tttcagcctc
    16021 ggctaatgct ttaacgttac catcaaagtc atttagcttg cgtaagtatc tctttcctct
    16081 ttcgtatgca ctaataggcc tataatcgtt accaatttgg gataaccaat gcatctgttc
    16141 atcgtcgaga tcaccaatta agacgcgata gtcacatcct gttaatatcg ctgcttttct
    16201 tctacgtgag ccgtcagcga cttcaacgat tccagatact tttctggcga aagctggatt
    16261 ttgttgtcca gacgttagaa aagatgggat taaatcggct agagaggatt catttaataa
    16321 atcttgatcg cgttcattac ctagccatac cattgttgcc atttcaactt tatctgcggg
    16381 aattgtctct aacttaaagt taacattacg tccgcatact ggcaaagtta tgctgttacc
    16441 ggttaatgaa ctcagttgac gttttaaatc accaaccata ggtgatacgg gctgatgttc
    16501 aggggcatga tgattattac tcataatgcg attaatatct ggagcatttt ttagaagaga
    16561 gcgctgtttc attattcgtt ctcccagcga ggttttatta gatcatcaaa aatttctcgg
    16621 caaacagggt cccatataga aacagcattt ctccatgcat tcaatgttga acgttggttt
    16681 gctgcttgtt caaatactgt tctcattttt atctggcctt tacctacttc atcggtaacg
    16741 cgtacaacct gacgtaatac cattgatccc catgtatttc ttatttgttc ttccatccat
    16801 cgtgattgat tccctgtagt gagactatat ttagtcagaa gtaagcgaac ggttggctca
    16861 aatccaccta ggtcaacgct ttccaataga tcgagaagca ttgtgaaaaa ctgtagaaca
    16921 gaagcgtaat caaataattc tgcaggtgta gcaacaacaa taacgtcagc ggcacaaaca
    16981 acgttaatgg ttcctgtacc gaggttcgga gcactatcta taacgataac atcgtagtta
    17041 tcccaaactg attcaatagc tgcgcgcagc ataaggtgtg gaggatgagg caatttaccc
    17101 tgagcatgat attgcatgag atctgtttct atacgatgta aagctaggca gctagggata
    17161 atgtctagtc caggccaaca tgttggcttt atagcatatt cagcgttatc gcgttctcct
    17221 aagtaaaatg gcagtaaagt atcctcggca tggatatgta aatcaggaac ataaccgtga
    17281 tacatagagg ccgtgccttg aggatcgtta ccttcaacca aaagaacacg atgaccttgt
    17341 aatgctaacc attgagcttg atgtaccgca gacgatgttt tataaacgcc gcctttgtgt
    17401 gacataacgg caagcacaac agggttttta tcttgtggtc gttggtttgg gttgccaaaa
    17461 actgctcgca tactgttgat ttgatctatg gtataaccag cacgacgttc aattcttcct
    17521 ctcatttcaa agtcaggtgc aggtaaacgc ccgctcttct cagcatctct aattgcttga
    17581 ggagttacac caattaaatc tgctacttca gttatacccc atcggcgggt gatacgccga
    17641 gcttcaggac tatcatcacc gaattgagcg atagcaattg cttgggtcat ttcttgacct
    17701 ctcgtaacac aatcttgcaa taactttttc aaagacatac tgtcatctcc agcttgtaac
    17761 tttgcttaat aattaaatct ttgcttattt ctagcaaatt tgcatgaaaa aggcaaagca
    17821 aaacaaaaaa cgcaaaggcg aatatttgag ctaaatcatc ttttgttccc ctcccgaaat
    17881 gcataaaacg aacaacaata taatcataac taattgatat ttattacctt ttctaagaaa
    17941 ggaaatcata taaaactaga gaaacatgat aagaatcatc aatgagatac gttttctata
    18001 ttagttatcc taaccttacc aacataagaa cacaaacaga gaacataaaa acaaagtaat
    18061 aacacaaaca caataaagaa cataaataaa gaattaaaac aaatgttaaa taaaaacagc
    18121 acgcaaactg agaacgttac actaaacgag aacactaatc aagaacatag
//
