LOCUS       CP088690               18877 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain C16EC0033 plasmid pC16EC0033-3, complete
            sequence.
ACCESSION   CP088690
VERSION     CP088690.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391591
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18877)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18877)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 194x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 13:24:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,037
            CDSs (total)                      :: 4,924
            Genes (coding)                    :: 4,697
            CDSs (with protein)               :: 4,697
            Genes (RNA)                       :: 113
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 227
            CDSs (without protein)            :: 227
            Pseudo Genes (ambiguous residues) :: 0 of 227
            Pseudo Genes (frameshifted)       :: 93 of 227
            Pseudo Genes (incomplete)         :: 161 of 227
            Pseudo Genes (internal stop)      :: 35 of 227
            Pseudo Genes (multiple problems)  :: 53 of 227
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18877
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="C16EC0033"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pC16EC0033-3"
                     /geo_loc_name="South Korea"
                     /lat_lon="37.34 N 127.92 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            15..101
                     /locus_tag="LQR02_25065"
                     /pseudo=""
     CDS             15..101
                     /locus_tag="LQR02_25065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229752.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            153..1554
                     /locus_tag="LQR02_25070"
                     /pseudo=""
     CDS             153..1554
                     /locus_tag="LQR02_25070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /name="DUF3560 domain-containing protein"
     gene            1601..2164
                     /locus_tag="LQR02_25075"
     CDS             1601..2164
                     /locus_tag="LQR02_25075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="UGI01139.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVTPAPVCDRLVML
                     AEISNRDHILEPSAGTGAILRAIRDTAPGAMCDAVEINSGLVRYLRENFNGVRVQCGDF
                     MEWLPVQYYSRVIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLPFSD
                     VREELPRGTFAYTDVPTMIIRLRA"
                     /name="class I SAM-dependent methyltransferase"
     gene            complement(2249..2358)
                     /locus_tag="LQR02_25080"
                     /pseudo=""
     CDS             complement(2249..2358)
                     /locus_tag="LQR02_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052655.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            2415..3112
                     /locus_tag="LQR02_25085"
     CDS             join(2415..2664,2664..3112)
                     /locus_tag="LQR02_25085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558270.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="UGI01140.1"
                     /translation="MASISISCPSCSATEGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            3129..3422
                     /locus_tag="LQR02_25090"
                     /pseudo=""
     CDS             3129..3422
                     /locus_tag="LQR02_25090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            3441..3938
                     /locus_tag="LQR02_25095"
     CDS             3441..3938
                     /locus_tag="LQR02_25095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein"
                     /protein_id="UGI01141.1"
                     /translation="MIMRCLAHIALVTVIQFIACYLVGWGKAETVFMLFFIVLWQGLFI
                     WLFSQIRKKRNVSDEFKFSKGVWYITMPVSSLLSPLLSLMVFIIGTLYELRRVSGCISI
                     KKWGQNQLKNQYDGSEKLDFGGIEQPPTTYYNPSTGYPMHGGFDSAGNTFGTRWQDYYD
                     RQ"
                     /name="entry exclusion protein"
     gene            3991..4701
                     /locus_tag="LQR02_25100"
     CDS             3991..4701
                     /locus_tag="LQR02_25100"
                     /inference="COORDINATES: protein motif:HMM:NF010291.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="UGI01143.1"
                     /translation="MVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIWLKPDSERT
                     VFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKMDLRESQG
                     WLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVNYTMITDV
                     QIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNANKVNLKFEEAKP
                     VLEDQLAKSIANIL"
                     /name="complement resistance protein TraT"
     gene            4904..5683
                     /locus_tag="LQR02_25105"
     CDS             4904..5683
                     /locus_tag="LQR02_25105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGI01142.1"
                     /translation="MTSDNIAEYVGENNQFTEKPVTEYPPVIQDNTVTTKDYLYSNNID
                     TDLLVVIGGLIVILFLMMLIMYFINSLRHKKLTEILGKISFPEKSGSNLLKPEAVSCNL
                     LSLCVLAPVLCTPRKLAEVSREIIVASAQEIAWTPGSSRIDGHQGENITWSLSSQSPAD
                     KYDLINKTSRVSPDSGRFYEPDTVLDHRERVRLFIQIQFPHGSDWSEVLRLTDIVTEKV
                     SSGRAAGGYHHRHTGYTWSVSHIILFCPVPDFPGVSS"
                     /name="hypothetical protein"
     gene            5740..7931
                     /gene="traD"
                     /locus_tag="LQR02_25110"
                     /pseudo=""
     CDS             5740..7931
                     /gene="traD"
                     /locus_tag="LQR02_25110"
                     /inference="COORDINATES: protein motif:HMM:NF021897.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /name="traD"
     gene            7931..13204
                     /gene="traI"
                     /locus_tag="LQR02_25115"
                     /pseudo=""
     CDS             7931..13204
                     /gene="traI"
                     /locus_tag="LQR02_25115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /name="traI"
     gene            13224..13970
                     /gene="traX"
                     /locus_tag="LQR02_25120"
     CDS             13224..13970
                     /gene="traX"
                     /locus_tag="LQR02_25120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="UGI01134.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLMV
                     LDHINLIFQLKQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQFAY
                     YLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAGLLM
                     LAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKS
                     LPRFWPGDFFPVFYACHLAVLGVLAL"
                     /name="traX"
     gene            14025..14582
                     /locus_tag="LQR02_25125"
                     /pseudo=""
     CDS             14025..14582
                     /locus_tag="LQR02_25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /name="fertility inhibition protein FinO"
     gene            14713..14925
                     /locus_tag="LQR02_25130"
     CDS             14713..14925
                     /locus_tag="LQR02_25130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGI01135.1"
                     /translation="MNGFRNSSRNGQVWCWQRAGSRAVILEVSGRRMEAAEAWRRAAGV
                     APRTDWQQFARKRAAHCHRRCRGRG"
                     /name="hypothetical protein"
     gene            15484..15909
                     /locus_tag="LQR02_25135"
     CDS             15484..15909
                     /locus_tag="LQR02_25135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="UGI01136.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVNDN
                     VIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTSTQTR
                     VSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
                     /name="IS66 family insertion sequence hypothetical protein"
     gene            15906..16256
                     /gene="tnpB"
                     /locus_tag="LQR02_25140"
     CDS             15906..16256
                     /gene="tnpB"
                     /locus_tag="LQR02_25140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311895.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="UGI01137.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLFI
                     FRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMLLDKLDWRQ
                     PKTSSRNSLTML"
                     /name="tnpB"
     gene            16287..17898
                     /locus_tag="LQR02_25145"
                     /pseudo=""
     CDS             16287..17898
                     /locus_tag="LQR02_25145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc23 family transposase"
                     /name="IS66-like element ISEc23 family transposase"
     gene            17976..18262
                     /locus_tag="LQR02_25150"
                     /pseudo=""
     CDS             17976..18262
                     /locus_tag="LQR02_25150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766809.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /name="DUF2726 domain-containing protein"
     gene            18334..18468
                     /locus_tag="LQR02_25155"
     CDS             18334..18468
                     /locus_tag="LQR02_25155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="UGI01138.1"
                     /translation="MTKYTLIGLLAVCATVLCFSLIFREQLCELNIHRGNTVVQVTLA"
                     /name="type I toxin-antitoxin system Hok family toxin"
     gene            18764..18877
                     /locus_tag="LQR02_25160"
                     /pseudo=""
     CDS             18764..18877
                     /locus_tag="LQR02_25160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052674.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     Typing          8308..8687
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="85.039"
                     /coverage="95.0"
                     /evalue="3.1100000000000003e-66"
     Typing          8723..9306
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="86.667"
                     /coverage="87.0"
                     /evalue="0.0"
     Typing          10254..13201
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="90.827"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5681..7251
                     /name="MPF_Unknown"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="91.238"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ccggagtttc acgggggcgt ggtgtacaca tccccgccat gaaaaacacg gccttcgggc
       61 aggtgctccg cacactcgaa ctgaaacgcg cttttaactg atgaggtgag ccgccccgcg
      121 aggggcggca acagacggaa ggagaacatt ttatgacatt agcagcaatc accatgaccg
      181 ccccggaagc cgccagccct gtgcagatgt accgcgcgac ctactcaccg gatgacaaca
      241 aactgcgcct gtatgccgtg tcacgtcttg accggagacg tataaaaaag tgcatgatgc
      301 cggtttccgc tgggcaccaa aacaggcgct gtttgtcgcg ccagcctgga caccgggccg
      361 gaagacgtgc tcctctcact tgccggagag attgaggatg aagacagcac gctcgctgaa
      421 cgtcaggaag cacgggcgga gggtttacgg atacagcgga aagcggccag tgaatccgcc
      481 acaggcactg tgatgaagtg gaaagacctc ggccgccctc cctcccccga tgtcatcccc
      541 cgccctgtca gcccattgct cttgtggggt cccatcacag ctgaacgccg cgccccgtct
      601 gtttgatgcg gcaagccgta tatgcaaaac ggcatgaaac gagccgtgac tgctcttcac
      661 tgaacgtgcg gaattactcg ggaagagcgg ggcgcggtcg gcactgctat cacgcgaagt
      721 ataagagaac gtccggacgt tcgctggcgt agtatcaaaa aaatcgaagc tgatttgcgc
      781 aaggctgaaa agaccatcgc gcagtcgcag aaatatctga cgatgtggcg ggctgaatcg
      841 ctggatctga atatggcaaa actcatcagc agtcatgacc atatcagcgc ctgtttcccg
      901 ctggatacgt atccgcgccc ggcagaaaaa agccagtatg aaggaagtcg atcgttatgg
      961 tcggccctgg atgatgacat catcaccacg gagcaggccc gcgaaattgc gatccgctgt
     1021 catgaacggc agattcagca tcaacaacgc tgggttaacc actatcagaa ccgcctgatc
     1081 tatgagcgtg ccatgctgga cgaaagcggc ggcgtggtta cccggacaca ggattttgag
     1141 ccgggcggac aggttttcag ccggggcgag tggctgacca tcatccgtgt gaacaaaagc
     1201 aacggggcgg tgagttcagt cacaacgcca aattacagtt ttctcgggta cagcggcacg
     1261 atgaaagtga cgcccgatcg catcacggac tacaaagcac catcggcaga agaggctgcc
     1321 gtcgccagtc aggccgcgaa gcgtccgccg gtagtcaact atccggggga aggtttccgg
     1381 gaaatgacaa aggcacagtg ggccgccctg ccccgggact gtaaggccgt gcgcagtgtg
     1441 gcagaagcag aagaccacgg ggcataccgg taccgccgca caatggacaa taatttccgc
     1501 ctggtgaatg tgtatatctc cgacatgaaa atcacggaaa tcccacagaa ataaggtata
     1561 tccccccggg aaaatccccg gggatgacgg agataatgat atgcacagtc agttaagaga
     1621 acgtatccgg ctgatgcgcg caaggctgga taacgccgcg ccggttgctg aaatccgggc
     1681 tgaatctcag ctttttgtga ctcctgcccc ggtctgtgat cgcctggtga tgctggcgga
     1741 gatcagcaac cgtgatcaca ttctggaacc ctctgccggc accggggcca tactgcgggc
     1801 gattcgggat accgcgccgg gggccatgtg tgatgcggtg gaaatcaaca gcgggctggt
     1861 ccggtatctg cgggaaaatt ttaacggtgt cagggttcag tgtggcgact tcatggaatg
     1921 gctgccggtg cagtattaca gccgggttat catgaatccg ccgttcagcc acgggcagga
     1981 tatccggcat atcctgcggg ccttttccct gttgcgtccg ggtggcgtgc tggtcgccgt
     2041 ctgtctcaac ggaccacgcc agcaggagaa gctgttaccg ttttctgacg tccgcgagga
     2101 gctgccgcgc ggcacgtttg cttataccga tgtcccgacg atgattattc gtctgcgtgc
     2161 ctgatgacac agggccggcg ggaggataaa tgcctgtctg cccgcgccgg gaaaaaacgc
     2221 gcgccggtgg cgctgaaagg ggccgcgctc acgcgccgcc cctttcatta cgcggacgtt
     2281 ctgatggggc ttctgtttct tcatgcctgt catttgtctg ttactgatgt tgttgttcct
     2341 gctactgcta ctgctactgg gtaatggtgc caacttactg atttagtgta tgatggtgtt
     2401 tttgaggtgc tcccgtggct tccatctcca tcagttgtcc ctcctgctca gctactgaag
     2461 gcgtggtgcg taacggtaaa agtactgccg gacatcagcg ctatctctgc tctcactgcc
     2521 gtaaaacatg gcaactgcag ttcacttaca ccgcttctca acccggtaca caccagaaaa
     2581 tcattgatat ggccatgaat ggtgttggat gccgggcaac cgcccgcatt atgggcgttg
     2641 gcctcaacac gattttacgt cacttaaaaa actcaggccg cagtcggtaa cctcgcgcat
     2701 acagccgggc agtgatgtga ttgtctgcgc tgaaatggac gaacagtggg gctacgtcgg
     2761 tgctaaatca cgtcagcgct ggctgtttta cgcgtatgac aggatacgga ggacggttgt
     2821 ggcgcacgtc ttcggtgaac gcactctggc cacactggag cgtcttctga gcctgctgtc
     2881 ggcctttgag gtcgtggtat ggatgacgga tggctggccg ctgtatgaat cccgcctgaa
     2941 gggaaagctg cacgtaatca gcaagcgtta cactcagcgc attgagcgac ataacctgaa
     3001 tctgagacaa catctggcaa ggctgggacg gaagtcactg tcgttctcaa aatcggtgga
     3061 gctgcatgac aaagtcatcg ggcattatct gaacataaaa cactatcagt aagttggagt
     3121 cattacccat tattgagcaa agaacgcagg acagtaatat ccgtaatgat gtaaaacatc
     3181 aggttgataa tatggtcaca gaatataaag ggaatatagg tgatactcag aacagcatac
     3241 gtggcgagga aaatattgta agaggacagt attctgaact acagaatcac cataaaacag
     3301 aggcattatc tcagaataat aaatataatg aagaaaagtc ggttcaggaa agaatgcccg
     3361 gggctgacag tccacaggaa ctgatgaaaa gggcaaagga gtatcaggat aagtataagt
     3421 aataatgctg tgtttgggag atgataatga gatgtctagc ccatattgct ctggtaacgg
     3481 tgatacagtt tatcgcctgc tatctggttg gttgggggaa ggccgaaaca gtttttatgc
     3541 tgttcttcat agtgctatgg cagggactgt ttatatggtt gttctctcaa atacgaaaaa
     3601 aacggaatgt gtcggatgag tttaaattca gtaaaggcgt ttggtatata acgatgccag
     3661 tatcttcctt actctctccg ttattaagcc tgatggtttt tatcattggt acactatacg
     3721 aattaaggcg agttagtggt tgcataagca taaaaaaatg gggtcaaaat caactcaaaa
     3781 accaatatga tgggagtgaa aagttagact tcgggggcat tgaacagccc ccaacgacct
     3841 actataaccc ttcaaccgga tatcctatgc atggaggctt tgactcagcg ggaaatactt
     3901 ttgggactcg ttggcaggat tattatgaca ggcaataaga aaactgtagt ttgtaaaaaa
     3961 ggtaatttga tgaaaacaaa aaaattaatg atggttgcac tggtcagttc cactctggcc
     4021 ctttcagggt gtggtgcgat gagcacagca atcaagaagc gtaaccttga ggtgaagact
     4081 cagatgagtg agaccatctg gcttaaaccc gacagcgaac gcacggtatt tctgcagatc
     4141 aaaaacacgt ctgataaaga catgagtggg ctgcagggca aaattgctga tgctgtgaaa
     4201 gcaaaaggat atcaggtggt gacttctccg gataaagcct actactggat tcaggcgaat
     4261 gtgctgaagg ctgataagat ggatctgcgg gagtctcagg gatggctgaa ccgtggttat
     4321 gaaggcgcag ctgttggtgc agcgttaggt gccggtatta ccggctataa ctcaaattct
     4381 gccggtgcca cactcggtgt gggccttgct gctggtctgg tgggtatggc tgcagatgcg
     4441 atggtggaag atgtgaacta taccatgatc acggatgtgc agattgcaga gcgtactaag
     4501 gcaacggtga caacggataa tgttgccgcc ctgcgtcagg gcacatccgg tgcgaaaatt
     4561 cagaccagta ctgaaacggg taaccagcat aaataccaga cccgtgtggt ctcaaatgcg
     4621 aacaaggtta acctgaaatt tgaagaggcg aagcctgttc tcgaagacca gctggccaaa
     4681 tcaatcgcaa atattctctg attatcttcc ggaggctggt ctgaccggcc tcctgactga
     4741 cgcctcgctt tgctcgttgt ccaaccccgg aaagaaataa aataaatttt atttctcccc
     4801 ggcgtttccg aaataaatat gaaaacactg agcggttgtg caaattcttt gtgcgaccgt
     4861 gaagtgttgc cggcgaagcc gggatcttcc ggagaaagtc attatgacat cagacaatat
     4921 cgctgaatat gttggtgaga ataatcaatt tactgagaag cctgtaactg aatacccccc
     4981 ggtgatacag gataatacag tgaccactaa agactatctg tacagcaata atattgatac
     5041 tgacctttta gtggttatcg gagggcttat tgttatattg tttctcatga tgcttatcat
     5101 gtactttatt aattctctca ggcataagaa attaactgaa atactgggaa aaatatcttt
     5161 tcctgaaaaa tccgggagca atttgcttaa accggaggcg gtcagctgta atttgttgtc
     5221 cctgtgtgtg ctggcaccgg tactctgtac acccagaaag ctggcagaag tctccaggga
     5281 gatcatcgtg gcgagtgcgc aggaaattgc atggacgccg gggagcagtc gtattgatgg
     5341 tcatcagggc gaaaatatta cctggtctct gtcatcgcag tctcctgccg ataagtatga
     5401 tctcatcaat aaaacgtccc gtgtttctcc tgacagtggc cgtttttatg aaccggacac
     5461 agttctggat caccgtgaac gggtacgcct ttttattcag atccagtttc cgcacgggag
     5521 tgactggtct gaagtattgc gcctgactga cattgttaca gagaaggtct cttccggcag
     5581 ggctgcaggc gggtatcacc accggcatac agggtacacc tggtctgttt cccacatcat
     5641 ccttttctgc cctgttccag attttcccgg agtttcatca tgagttttaa cgcaaaggat
     5701 atgacccagg gcggtcagat tgcgtccatg cgtatccgca tgttcagcca gatcgccaat
     5761 atcatgcttt actgcctgtt tatttttttc tggatactcg ttggtctgat tttatgggta
     5821 aaaataagct ggcagacgtt tgtgaacggc tgtatttact ggtggtgtac cacgctggaa
     5881 ggcatgcggg atttaatcaa gtcccagcca gtatatgaga ttcagtatta cggcaaaacc
     5941 ttccggatga acgctgccca ggtactgcat gataaatata tgatctggtg cggtgagcag
     6001 ctatggtccg cattcgttct ggcgtctgtc gtggccctgg ttatttgcct gatcaccttc
     6061 tttgttgtct cctggattct ggggcgtcag ggtaaacaac agagcgaaaa tgaagtcaca
     6121 ggtggtcgtc agctgacaga caatccgaaa gacgttgccc ggatgctgaa aaaagacggc
     6181 aaggactccg atatccggat tggcgacctg ccgattatcc gggattccga aatccagaaa
     6241 cttctgtctg cacggcacgg tcggggccgt aagtcggagg ttatccgtcg tctggccaac
     6301 tatgcccgtc agcgcggtga tatggtggtg atttatgacc gttcagggga atttgttaaa
     6361 agttactatg atccctccat cgataaaatc ctgaatccgc tggatgcccg ctgtgccgca
     6421 tgggatttgt ggaaggagtg cctgacacag ccggattttg ataataccgc aaatactctg
     6481 atccctatgg gtacaaaaga ggacccgttc tggcagggtt caggacgtac catttttgcg
     6541 gaagcggcgt acctgatgcg taatgacccc aaccgcagct acagcaaact ggtggacaca
     6601 ctgctttcca tcaaaattga aaaactgcgt accttcctgc gtaattcacc ggcggccaac
     6661 ctggtggaag agaaaattga gaaaacggcg atttccatcc gtgctgtgct gaccaactac
     6721 gtgaaagcca tccgttacct gcaggggatt gagcataacg gtgagccctt caccatccgt
     6781 gactggatgc gtggtgtccg ggaagatcag aaaaacggct ggctgtttat ttcgtcgaac
     6841 gccgacaccc atgcctccct gaagcctgtg atctccatgt ggctgtccat tgccattcgt
     6901 ggtctgctgg caatgggaga aaaccgtaac cgtcgtgtgt ggtttttctg tgatgagtta
     6961 cccacgttac acaaactgcc ggacctggtg gagatcctgc cggaagcccg taagttcggt
     7021 ggctgttatg tgtttggtat ccagtcctat gcccagctgg aagatatcta cggtgagaaa
     7081 gcggcggcca cgctgtttga cgtcatgaac acccgtgctt ttttccgttc ccgagccata
     7141 agattgcaga gttcgctgcc ggtgagattg gtgagaaaga gcacctgaaa gccagcgagc
     7201 agtattccta cggtgctgac ccggtacgtg acggggtatc gaccggtaag gatatggagc
     7261 gtcagacact ggtcagttat tccgacattc agtctctgcc ggatctgacc tgctatgtca
     7321 ctctgcccgg accgtatccg gcagtaaaac tctccctgaa atatcaggca cgaccgaagg
     7381 tcgctccgga gtttattccg cgtgacatca acccggaaat ggagaaccgt ctgagtgccg
     7441 tacttgctgc aagggaagca gaaggtcgcc agatggccag cctcttcgaa ccggaggttg
     7501 cctccggaga aggcgtgact caggctgaac agccacaaca gccacaacag ccacaacagc
     7561 cacaacagcc acaacagcca caacagccac aacagccaca acagccacaa cagccacaac
     7621 agccacaaca gccacaacag ccacaacagc cagtgtcttc tgtcatcaat gataagaagt
     7681 cagatgcagg tgtgagtgtt ccggcagggg ggatcgagca ggagctgaaa atgaaaccgg
     7741 aagaagagat ggaacagcaa ctgccacccg ggatcagtga atccggtgaa gtggtggata
     7801 tggccgctta tgaggcatgg caacaggaaa atcatccgga catccagcag cagatgcagc
     7861 gtcgtgaaga ggtgaacatt aatgtgcacc gggagcgcgg ggaggatgtt gagccgggag
     7921 atgatttctg atgttgagtt tcagcgttgt taaatcggca ggcagtgccg gaaactatta
     7981 caccgacaag gataattact atgtgctggg cagcatggag aacgctgggc cggtcagggg
     8041 gctgaacagc ttgggctgca gggcagcgtc gataaggatg tttttacccg tcttctggag
     8101 ggcaggctgc cggacggggc ggatttaagc cgcatgcagg atggcagtaa taagcatcgt
     8161 cccggctacg acctgacctt ctccgccccc aaaagtgtct ccatgatggc catgctcggg
     8221 ggggataaac gtcttattga tgcacataac caggctgtgg attttgctgt ccgtcaggtg
     8281 gaggcgctgg cttccacacg ggtgatgacg gacggacagt ccagaaaacg gtgctgaccg
     8341 gtaatctggt gatggcactg tttaaccatg acaccagtcg cgatcaggac ccacagttac
     8401 acacgcatgt ggtggtggct aatgtcacgc agcataacgg cgaatggaag acactgagca
     8461 gtgacaaagt ggggaaaacc ggattttccg agaacgtgct cgcgaaccgg attgcgttcg
     8521 ggaaaatata tcagagtgag ttacgtcagc gcgttgaggc gctgggttat gaaaccgaag
     8581 tggtcggtaa gcacggtatg tgggagatgc cgggcgtacc ggtggaagcc ttctccggac
     8641 gctcacaggc tatccgggag gccgtcggtg aagacgcctc gctgaatccc gggatgtggc
     8701 ggcactggat acgcgtaaat ccaacagcac gtcgatcctg aagtcagaat ggctgaatgg
     8761 atgcagacgc tgaaggaaac cgggttcgac atccgggcat atcgtgacgc ggcggatcag
     8821 cgtgcggaga tccgcacgca ggcgcccggg cctgcttcac aggacgggcc ggatgtgcag
     8881 caggcggtga cacaggccat tgccggatta agtgaacgaa aagtgcagtt cacgtatacg
     8941 gacgtgctgg ccaggacggt cggcatactg ccgccggaaa atggtgtgat tgaacgggca
     9001 cgcgccggta tcgatgaggc catcagccgt gagcagctta tccccctcga tcgtgagaag
     9061 gggctgttca cgtccgggat tcatgtgctc gatgagctgt cagtccgggc actcagtcgt
     9121 gacatcatga aacagaaccg ggtgaccgta catccggaga aaagtgtccc ccggacggcc
     9181 ggttacagcg atgccgtcag tgttctggca caggatcgcc cgtcgctggc cattgtgtcc
     9241 gggcagggcg gtgcagccgg gcagcgtgag cgggtggctg aactggtcat gatggcccgg
     9301 gagcaggggg cgggaggtgc agattatcgc tgctgaccgt cgctcgcaga tgaacctgaa
     9361 gcaggatgaa cggctgtccg gtgaactgat aaccggacgt cgtcagttgc tggaaggcat
     9421 ggccttcccg ccgggcagta ccgttatcgt cgaccagggc gaaaaaactc tccctgaaag
     9481 agacgttaac cctgctggat ggtgccgcac gtcataacgt acaggtcctg ataaccgaca
     9541 gcgggcagcg aaccggtaca ggcagtgcac tgatggccat gaaggatgcc ggggtgaaca
     9601 catatcgctg gcagggggga gaacagcgac cggccaccat catcagtgaa ccggaccgta
     9661 atgtccgcta tgcccggctg gccggagatt ttgcggccag cgtgaaagcc ggagaagaga
     9721 gcgtggcaca ggtcagcggg gtacgggaac aggccaatac tgacagaggc cattcgcagt
     9781 gagctgaaaa cgcagggcgt gctcggacac cctgaggtga ccatgactgc actgtcaccg
     9841 gtctggctgg acagccggag ccgttatctg cgggatatgt accgaccggg gatggtgatg
     9901 gagcagtgga acccggagac acgcagtcat gaccgctatg tgatagaccg ggtgacagcg
     9961 cagagtcaca gcctgaccct gcgggatgcg cagggcgaaa cgcaggtggt gcgtatttcc
    10021 tccctggaca gcagctggtc gctgttccgg ccggaaaaaa tgccggtggc agacggcgag
    10081 cgactgaggg tgacagggaa aattcccgga ctccgcgtct ccggcggtga ccgcctgcag
    10141 gtggcatccg tcagtgaaga tgcgatgacg gttgttgtgc cggggcgggc tgaaccggcc
    10201 accctgcctg tggctgattc accattcacg gcactgaagc tggagaacgg ctgggtggaa
    10261 acgcccgggc attccgtcag cgacagtgcg acggtttttt gcctccgtca cacagatggc
    10321 gatggacaac gcgaccctga acggtctggc ccgcagtggt cgtgatgttc cggctgtatt
    10381 cctcgctgga tgaaccccgt actgcggaaa aacttgcccg ccatccctcc tttacggtgg
    10441 tttctgatca gataaaggcg cgtgccggtg agacattgct ggaaaccgct atcagtctgc
    10501 agaaagccgg gcttcacacg ccggcacagc aggccattca tctggccctt cctgtgctgg
    10561 aaagtaaaaa cctgccttca gcatggtgga cctgctgaca gaggcgaagt cgtttgctgc
    10621 agaaggaacc ggttttactg aactgggagg ggaaatcaat gcgcagataa aacgcggtga
    10681 cttactgtat gtggatgtgg caaaaggcta tggcacaggt ctgctggttt cccgtgcgtc
    10741 gtatgaggca gaaaaaagta ttcttcgcca tattctcgaa ggtaaggagg cggtcacgcc
    10801 gttgatggag agagtacccg gcgaactcat ggagacgtta acgtcgggac agcgtgccgc
    10861 cacccgtatg atactggaaa cgtccgaccg tttcacggtg gtacagggtt atgccggtgt
    10921 gggtaagacc acacagttcc gggcggtgat gtcagccgtg aacatgctgc cggcgagtga
    10981 gcgtccccga gttgtggggc tggggcccac gcaccgtgcg gtcggtgaga tgcgcagcgc
    11041 cggcgtggat gcacagacgc tggcgtcctt tctgcatgac acgcagctgc agcagcgcag
    11101 cggagaaacg ccggatttca gcaacacgct gttcctgctc gatgagagct caatggtggg
    11161 caataccgat atggcacggg catacgccct gattgcggcc ggtggcggtc gtgccgtggc
    11221 cagtggtgac acggaccagc tgcaggccat cgcgcccggt cagcctttcc gtctgcagca
    11281 gacgcgcagt gctgccgatg tggtcatcat gaaggagatt gtgcgtcaga cgccggaact
    11341 gcgggaggcg gtatacagcc tgattaaccg ggatgtggaa agggcactgt ccgggcttga
    11401 gagtgtgaaa ccgtctcagg ttccccgtca ggagggcgca tgggcaccgg agcactccgt
    11461 gacggagttc agtcacagcc aggaagcgaa actggcagaa gcgcagcaga aggcgatgct
    11521 gaaaggcgag gctttcccgg atatccccat gacactgtat gaggccattg tccgcgacta
    11581 taccggcagg acaccggaag cacgggagca gacgctgatt gtcacgcacc tgaatgagga
    11641 ccggcgcgta ctgaacagca tgattcatga tgcacgggaa aaggccggtg agctgggcaa
    11701 agagcaggtc atggtgcctg tcctgaacac agcgaatata cgtgacggag aactgcgtcg
    11761 tctctccacc tgggagaata acccggatgc ccttgccctg gtggatagtg tgtatcaccg
    11821 gattgccggt atcagcaagg atgacgggct gataaccctg gaggatgcgg aaggtaacac
    11881 gcggctgatt tcgccccggg aggcggtggc tgaaggtgtc acactgtaca caccagacaa
    11941 aatccgggtg ggaaccggtg accggatgcg cttcacgaag agtgaccggg agcgcggtta
    12001 tgtggccaac agcgtctgga cggtgacagc ggtttccggt gacagtgtca cgctgtcgga
    12061 cggacagcag acccgggtga ttcgccccgg tcaggagcgg gcagagcaac atattgacct
    12121 ggcctatgcc atcaccgccc acggtgcgca ggggacaagt gaaacctttg ccattgcgct
    12181 tgaaggcacg gaaggtaacc ggaaactgat ggcaggcttt gagtcagcct acgtggccct
    12241 gtcgcgtatg aagcagcatg tgcaggtgta caccgataac cgtcagggct ggacggatgc
    12301 cattaacaat gccgtacaga aaggaacagc ccacgatgtg tttgagccga aaccggaccg
    12361 ggaggtcatg aatgcgcagc ggctgttcag tacggcacgg gaactgcggg acgtggcggc
    12421 aggccgtgcc gttctccgtc aggcggggct ggccggggga gacagccctg cacggtttat
    12481 tgcaccggga cgtaaatatc cgcagccgta tgtggcactg ccggcgtttg accgtaacgg
    12541 caggtccgcc ggtatctggc tgaacccact gaccacggat gacggaaacg ggctgcgggg
    12601 attcagcggt gaaggacggg tgaaaggccg cggggatgcg cagttcgtgg ccctgcaggg
    12661 cagccgtaac ggagagagcc tgctggctga taatatgcag gatggtgtcc ggattgcccg
    12721 tgataatccc gacagcggtg tggtggtaag aattgccggt gaaggtcgtc cgtggaatcc
    12781 cggtgccatc accggtggtc gcgtgtgggg ggatatcccg gacagcagcg tccagccggg
    12841 ggccggaaat ggcgaaccgg tcacggcaga ggtgctggca cagcggcagg ctgaagaggc
    12901 catccgccgt gaaacggaac gtcgcgcaga tgaaattgtc cgtaaaatgg cagagaacaa
    12961 acctgacctg ccggacggca aaacagagct ggctgtcagg gatattgccg ggcaggaacg
    13021 tgaccggact gccagttctg aacgggaaac cgcactgccg gagagtgtgc tgcgtgaatc
    13081 acaacgggaa cgggaagcgg tccgggaggt tgcccgggaa aatctgctgc aggagcgtct
    13141 gcagcagatg gagcgggata tggttcgtga cctgcagaaa gagaaaaccc tgggcggaga
    13201 ctgatacagg aagacaaaca ctgatgacaa cggataacac gaacacgaca cgtaacgatt
    13261 cactggctgc acggaccgat acctggttgc agtcatttct ggtctggtca cccggacagc
    13321 gggatatcat caaaacggtg gcactggtgc tgatggtact ggaccacatc aatctgatat
    13381 tccagctgaa gcaggaatgg atgtttctgg ccgggcgagg agcctttccg ctgtttgccc
    13441 tggtgtgggg gctgaatctg tcccgtcatg cgcatatccg gcaaccggcc attaaccggc
    13501 tgtggggatg gggaattatt gcccagttcg catattatct ggccggcttt ccctggtatg
    13561 aggggaatat cctgtttgcc tttgcagtgg cggcacaggt gctgacgtgg tgtgaaacgc
    13621 gcagtgggtg gcgtacagca gcggccattc ttctgatggc cctgtggggg cctttgtccg
    13681 gcaccagtta cggcattgcc gggctgctga tgctggcagt cagccaccgg ctgtaccggg
    13741 cggaagacag agcggaacgt ctggcgctgg tcgcctgcct gctggctgtt attccggcgc
    13801 ttaaccttgc caccagtgat gcagcggcgg tggccggtct tgtgatgacg gtgctgaccg
    13861 ttggtctggt gtcgtgtgca ggaaaatcat taccccgttt ctggcccggg gattttttcc
    13921 cggtattcta cgcctgtcat ctggctgtgc tgggcgttct ggcgctgtga cgggtgtggt
    13981 atctttggcc gcaagaggat gattcgtcag aggcagaaca cagcatgaca gagcagaagc
    14041 gaccggtact gacactgaag cggaaaacgg aaggggagac gcctgtccgc agccggaaaa
    14101 ccatcatcaa tgtcaccacg ccaccaaagt ggaaggtgaa aaagcagaag ctggccgaga
    14161 aagcagcccg ggaagcagag ctggcggcaa aaaaagcgca ggccagacag gcgctgtcca
    14221 tttatctgaa cctgcccaca ctggatgagg ctgtgaacac cctgaagccc tggtggccgg
    14281 gattatttga cggtgacacg ccccggcttc tggcctgcgg tatccgggac gtgttactgg
    14341 aagacgtggc gcagcggaat atcccgctct cgcataaaaa actgcgcagg gcgctgaagg
    14401 ccatcacccg ttcagaaagc tatctgtgtg ccatgaaagc cggtgcctgc cggtatgata
    14461 cggaagggta tgtgacggag catatttcag gaggaggaag cgtatgcggc agcgcgtctg
    14521 gataaaatcc gcgccagaac cggataaagg cagaacttca ggccgtgctt gatgagaaat
    14581 aaaaaaagcc tccctcaggg aggggaggca gggaaataag gcttaaaagg aaataacttc
    14641 cgtacccgaa agaaagccat tccactgagc tatttatcac aataatactg acaactaaag
    14701 ggggacagaa atatgaatgg attcagaaac agttcacgga acggtcaggt ctggtgctgg
    14761 cagcgtgccg gaagccgggc cgttattctg gaggtcagtg gacgcaggat ggaagcggca
    14821 gaagcatggc gacgggctgc cggtgttgcg ccccggacag actggcagca gtttgcccga
    14881 aaaagggctg cacactgcca ccggcgttgc cggggaaggg ggtaacgaaa aaagcagcct
    14941 tcattactcc aggagtcaga aggctgaaag aagtttatga gatttgcttt ttttaatatc
    15001 cggtcgggaa gtatgaccgg acagttctga gtagcacaga tttttttccg tattaagtcg
    15061 agattttata ttttgtgatt aatttcacaa aataaggtgt tgttcaatgt gtgctgtaat
    15121 attcaggatg tctgaaatac aggtgccatt tatttgatat ggagagtaac atgaggaaat
    15181 atattccacg ggtattattt atcttttcat ggcggtatta acttccctag tttcatcttc
    15241 ataccttatt gggtgtatta aaaacagtag gctgccaaag tcttaaacaa gtttcaattc
    15301 tccatgacag ttcaacatca gccagaggaa attcccattc tggaccagcg ggagcatacg
    15361 aacaataatt ttcggcttcg cgctatagcg ggctcaaggt aagcgtaaac tgaccgccgt
    15421 atgtagccat cagacgagaa ttggtaactt agacgcccat ctgatataga cggacatcta
    15481 agtatggaat tacaggactg gcgaaaagaa cctcgtaaaa actattcgaa tgaattcaaa
    15541 cttcgtatgg tggaactggc atcacaacct ggagcttgtg ttgcacagat tgcacgtgaa
    15601 aatggcgtca atgataatgt tattttcaaa tggctcaggc tctggcagaa cgaagggcgt
    15661 gtttcgcggc gtcttccggt aacgacctct tctgacactg gcgttgaatt attacctgta
    15721 gaaataacgc cggatgagca gaaagaacct gtggcggcca ttgcgccgtc tttatccact
    15781 tccactcaga ccagagtcag tgccagttcc tgcaaggtgg aattccgtca cggtaacatg
    15841 acgctggaaa atccatcgcc agagctgctc acagtgttga tccgtgaact gaccgggagg
    15901 ggaagatgat ctcactccca tcaggtaccc gtatctggct cgttgccggc gttaccgata
    15961 tgcgtaaatc cttcaacgga ctgggagaac aggtacaaca tgtgctgaat gataatccct
    16021 tctccggtca cctgtttatc ttccgtggcc gacggggtga caccgtcaaa attctttggg
    16081 ctgatgctga tggtctgtgc ctgttcacca aacgcctgga ggaaggccag tttatctggc
    16141 ctgcggtacg tgacggcaag gtatccatta cccgctcgca actggcaatg ctcctcgata
    16201 agctggactg gcgtcagcca aaaacatcca gccgtaactc actgacaatg ttgtaaaaaa
    16261 ctcctgaccg cattataaaa acggtcatga gtcagaaata cctcattcgc atcgcagagc
    16321 tggaaaggtt gctctctgag caggctgaag ccccccgtca gaaagaccag caactgagtc
    16381 tggttgaaga gacggaagcc ttcctgcgct ctgcactgac acgtgccgaa gaaaagatcg
    16441 aagaagatga acgggaaata gaacatctgc gggctcagat agaaaaactg cgccggatgc
    16501 tgttcggtac ccgttctgaa aaactgcgtc gtgaagttga actggctgag gctctgctga
    16561 aacaacgtga acaggacagc gatcgttaca gtgggcggga agacgatcct caggttcccc
    16621 gccagttgcg acagtcgcgc catcgtcgtc cgttaccggc acaccttccc cgtgaaatac
    16681 accgcctgga gccagaagaa agctgttgcc cggagtgtgg cggtgagctg gattatctgg
    16741 gggaagtcag cgctgaacag ctggaactgg tgagcagtgc cctgaaagtg atccgcacag
    16801 aacgggtaaa aaaagcctgt acaaaatgtg actgtattgt tgaagcaccg gcgccgtccc
    16861 gcccgataga gcgtggtatc gcgggcccgg attacttgcc cgcgtgttaa cgggaaaata
    16921 ctgcgaacat ctgccactgt atcgtcagag tgaaatcttt gcccgccagg gtgtcgaact
    16981 gagccgggcc ttactctcca actgggttga cgcgtgctgc cagttaatga caccggtgaa
    17041 tgatgccctg taccgttatg taatgaacac ccgcaaggtt cacactgatg acacaccggt
    17101 aaaggtactg gcaccgggtc agaaaaaggc gaaaacaggg cgtatctgga cgtatgtccg
    17161 ggatgatcgc aatgtgggtt cgtcatctcc tccagcggtc tggttcgcgt actcgccgaa
    17221 ccggcagggg aaacacccgg agcaacacct ccgcccttcc ggggtatcct gcaggcggat
    17281 gcgttcacag gttacgacag gttgttcagt gcagaacgtg aaggtggtgc actgacagaa
    17341 gttgcgtgct gggcccatgc ccggcgaaaa atccacgatg tatacatcag cagcaaaagt
    17401 gcgacggcag aagaagccct gaagcgaatc agtgaactgt acgccatcga ggatgaaata
    17461 cggggattac cggagtcaga gcgtcttgcc gtcaggcagc agcgaagcaa agtgttactg
    17521 acgtcgctgc atgaatggat ggtggagaag aatggtacgc tgtcgaaaaa atccagactg
    17581 ggcgaagcgt tcagctatgt actgaatcag tgggatgccc tctgttatta cagtgatgac
    17641 ggtctggcgg aggcggataa taatgctgcg gaaagagcgc ttcgtgcagt ctgtctcgga
    17701 aagaaaaact ttatgttctt tggcagcgat cacggcggcg agcgtggagc actgttgtac
    17761 gggctgatcg gcacctgccg tctgaacggt atcgatccgg aagcgtatct gcgccatatc
    17821 ctgagcgtac tgccggaatg gccttccaac cgagttgacg aactcctgcc atggaacgta
    17881 gtactcacca ataaataagc gtcaatacgg tgctccgttg acgcttacgg ctcaagttag
    17941 gttgtcccct gaatctccag acaactaata tctgatcgcg ccagtggtgg ctgttattca
    18001 ggatggtatc tcagtgcatg tcgatgtggt tatcgttgaa cggcgttcgt tcagtattgt
    18061 tgcagcagta tagctggctg atgacagtca tttacgttcg gaacgcagat gctgggatac
    18121 tcttctggaa gaggttctga ggcaggctgg cattccgttg ctcagaagtc acgatgcaag
    18181 aaaactgctg cagatgaccg aagaatggct gaataagacg caggtttcag aaatgcgaag
    18241 accccactcg ttaatccatt aactcgtgag gtctgcatga tgcactttag cactactgat
    18301 tgtagcctct tctttgcaaa gatgtcaaag tttatgacga aatataccct tatcgggttg
    18361 cttgccgtgt gcgccacggt gttgtgtttt tcactgatat tcagggaaca gttatgtgaa
    18421 ctgaatattc acaggggaaa tacagtggtg caggtaactc tggcctgaag cacggaagta
    18481 agctgccggg cggggacgga agtccccgct ttccggaagt gtgaggtatt tcaggggcag
    18541 acacccgaaa tgctagaaac tgccggtccc gcccggggcc ggtaccctgg ttaaagcatt
    18601 tcctactttt cagtcattta ttatcaaaat tacattaaac ggtcgtaatc agacatgatt
    18661 tgtgcgccaa cacagatcat cgtcacaact ttcaagtcgc tgatttcaaa aaactgtagt
    18721 attctctgcg aaacgatccc tgtttaagta ttgaggaggc gagatgtcgc agacagaaaa
    18781 tacagtgact tcctcatctg gcgcaaaacg agcatacaga aaggggaatc cgctttctga
    18841 tgcagagaaa caaagattat cagtggcccg taaaaga
//
