LOCUS       CP088622               18284 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain C17EC0146 plasmid pC17EC0146-1, complete
            sequence.
ACCESSION   CP088622
VERSION     CP088622.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391617
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18284)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18284)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 305x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 11:50:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,259
            CDSs (total)                      :: 5,146
            Genes (coding)                    :: 4,912
            CDSs (with protein)               :: 4,912
            Genes (RNA)                       :: 113
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 89 of 234
            Pseudo Genes (incomplete)         :: 179 of 234
            Pseudo Genes (internal stop)      :: 40 of 234
            Pseudo Genes (multiple problems)  :: 64 of 234
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="C17EC0146"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pC17EC0146-1"
                     /geo_loc_name="South Korea"
                     /lat_lon="37.34 N 127.92 E"
                     /collection_date="2017"
                     /collected_by="Kor-GLASS"
     gene            join(17384..18284,1..8)
                     /locus_tag="LQR15_25490"
                     /pseudo=""
     CDS             join(17384..18284,1..8)
                     /locus_tag="LQR15_25490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            1..206
                     /locus_tag="LQR15_25495"
                     /pseudo=""
     CDS             1..206
                     /locus_tag="LQR15_25495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566927.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /name="molecular chaperone"
     gene            288..863
                     /locus_tag="LQR15_25500"
                     /pseudo=""
     CDS             288..863
                     /locus_tag="LQR15_25500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein papJ"
                     /name="protein papJ"
     gene            1184..1408
                     /locus_tag="LQR15_25505"
     CDS             1184..1408
                     /locus_tag="LQR15_25505"
                     /inference="COORDINATES: protein motif:HMM:NF012635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="UGG95628.1"
                     /translation="MNAGRLGIALLDTDGSSLLKPGTSHNKGQGEKVTETVLSFLSARM
                     FVATPEALRTKSVVPGDYEATATFELTYR"
                     /name="fimbrial protein"
     gene            1435..1960
                     /locus_tag="LQR15_25510"
                     /pseudo=""
     CDS             1435..1960
                     /locus_tag="LQR15_25510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723802.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /name="fimbrial protein"
     gene            2035..2531
                     /locus_tag="LQR15_25515"
                     /pseudo=""
     CDS             2035..2531
                     /locus_tag="LQR15_25515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042092232.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /name="fimbrial protein"
     gene            2575..3432
                     /locus_tag="LQR15_25520"
                     /pseudo=""
     CDS             2575..3432
                     /locus_tag="LQR15_25520"
                     /inference="COORDINATES: protein motif:HMM:NF015583.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /name="fimbrial protein"
     gene            complement(3968..4714)
                     /gene="istB"
                     /locus_tag="LQR15_25525"
     CDS             complement(3968..4714)
                     /gene="istB"
                     /locus_tag="LQR15_25525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family helper ATPase
                     IstB"
                     /protein_id="UGG95633.1"
                     /translation="MNHLYEQLTALKLTGFRDALKKQLAQPGTYQELGFEERLSLLTAE
                     ELTCRENRKAERLIKHARFRLNAELSKLDYRNNRGLDRALIRSLSQGNWLTLKQNILLT
                     GATGSGKTFLACALGHNACRQGYKVYYYRLKALMEQCYQGHADGRYSKLLTRLNNSDLL
                     LLDDWGLEPLSSEQRSDLLEIVDLMYQRGSIIVVSQLPVENWYKMIGDSTHADAILDRL
                     VHGSIKIELKGESMRKIQSPLTEGDQ"
                     /name="istB"
     gene            complement(4729..6270)
                     /gene="istA"
                     /locus_tag="LQR15_25530"
     CDS             complement(4729..6270)
                     /gene="istA"
                     /locus_tag="LQR15_25530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="UGG95629.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYANR
                     AAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLWEE
                     YCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPETGEI
                     RTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSATSRA
                     CKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHEIFYSL
                     ASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKKVRVHAD
                     YHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYSTRNEHMPE
                     AHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNLHKKYSKAR
                     LNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRGSEYYH"
                     /name="istA"
     gene            complement(6573..6851)
                     /locus_tag="LQR15_25535"
                     /pseudo=""
     CDS             complement(6573..6851)
                     /locus_tag="LQR15_25535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648830.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="pdcB"
                     /name="pdcB"
     gene            complement(6879..7058)
                     /locus_tag="LQR15_25540"
     CDS             complement(6879..7058)
                     /locus_tag="LQR15_25540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PdcA protein"
                     /protein_id="UGG95630.1"
                     /translation="MARKYNKLSREALKMLLDGVSRREVKQYLAGKQIGARTAIAVLCR
                     QEMVVLKQRMPGSR"
                     /name="PdcA protein"
     gene            complement(7063..7443)
                     /locus_tag="LQR15_25545"
     CDS             complement(7063..7443)
                     /locus_tag="LQR15_25545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="UGG95631.1"
                     /translation="MRHISPEELIALHDANINRYGGLPGMSDPGRAEAIIGRVQARVAY
                     EEITDLFEVSATYLVATARGHIFNDANKRTALNSALLFLRRNGVQVFDSPELADLTVGA
                     ATGEISVSSVADTLRRLYGSAE"
                     /name="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(7443..7664)
                     /locus_tag="LQR15_25550"
     CDS             complement(7443..7664)
                     /locus_tag="LQR15_25550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="UGG95632.1"
                     /translation="MQSINFRTARGNLSEVLNNVEAGEEVEITRRGREPAVIVSKATFE
                     AYKKAALDAEFASLFDTLDSTNKELVNR"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            7847..9160
                     /locus_tag="LQR15_25555"
                     /pseudo=""
     CDS             7847..9160
                     /locus_tag="LQR15_25555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005767712.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /name="type I restriction-modification system subunit M"
     gene            9212..9909
                     /locus_tag="LQR15_25560"
     CDS             join(9212..9461,9461..9909)
                     /locus_tag="LQR15_25560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
                     /protein_id="UGG95621.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1A family transposase"
     gene            complement(10046..10978)
                     /locus_tag="LQR15_25565"
     CDS             complement(10046..10978)
                     /locus_tag="LQR15_25565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-4TM family putative pore-forming effector"
                     /protein_id="UGG95622.1"
                     /translation="MNAIYTNQSTRENMDLLYAQARVYDRVKNWNRLNFLFSIIVPLLL
                     SFVTVYNRSREFVDSELLSSLLGLYGLLVLTFNIVISGHISALRRKAASIQEMYDCRVL
                     GIRRNELKVEEIPRDDIIREAAYFRDSPEKARKRFGEEGWYVSKVYDAPQAVMALLCHG
                     KNLGWDKSLREVLHVFYLSAFIVSPVAMLVYGIVMKSGLNEILFYVVFTLPVIRYFLLQ
                     FLDNRSSMKRSEKLKKYVEKELSGIRVSGRAEEEQLAYTLRNIQDEMFTYRASCPPVPN
                     GIQLIMKPKNERIYVDYFETNLKELHLQK"
                     /name="S-4TM family putative pore-forming effector"
     gene            complement(10982..11977)
                     /locus_tag="LQR15_25570"
     CDS             complement(10982..11977)
                     /locus_tag="LQR15_25570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013578371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="UGG95623.1"
                     /translation="MATTVIAAFNEFMKDTVNLKKADTDDARASRDWLIGKMNDFEKDD
                     KFPVSFPAIHIAFGSFARRTKIRPLDDIDLMFGLTGQGATYTILSDRITVTSSGEGSRL
                     HSYRHSGADTVCSVRILNAFKNRLQDIAQYAQADIRRNQEAVTLKLVSKDWNFDIVPCF
                     ITSEDAFGRTYYLIPDGNGHWKFTDPRKDRDRVTTINVQNNGNVLNVIRAVKYWQRRPT
                     MPSMSSYLLETLILDYYAGRTSCSSFVDMELEALFRHLGQSVRYSVNDPKGIQGDINSL
                     SAEARKAISDRCYLDAQKVSEARWFENNKEYEKSINKWRDVFGPFFPVYG"
                     /name="nucleotidyltransferase"
     gene            12685..12903
                     /gene="ccdA"
                     /locus_tag="LQR15_25575"
     CDS             12685..12903
                     /gene="ccdA"
                     /locus_tag="LQR15_25575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="UGG95624.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERWK
                     AENQEGMAEVARFIEMNGSFADENRDW"
                     /name="ccdA"
     gene            12905..13210
                     /gene="ccdB"
                     /locus_tag="LQR15_25580"
     CDS             12905..13210
                     /gene="ccdB"
                     /locus_tag="LQR15_25580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="UGG95625.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDK
                     VSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
                     /name="ccdB"
     gene            13211..14017
                     /locus_tag="LQR15_25585"
     CDS             13211..14017
                     /locus_tag="LQR15_25585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="UGG95626.1"
                     /translation="MSGSVIHSQSAVMVPAVYSAGQPASLPVAIDYPAALALRQMSMVH
                     DELPKYLLAPEVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPFVQ
                     LATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRRTGR
                     TEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVL
                     QSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
                     /name="site-specific integrase"
     gene            14790..15545
                     /gene="repE"
                     /locus_tag="LQR15_25590"
     CDS             14790..15545
                     /gene="repE"
                     /locus_tag="LQR15_25590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="UGG95627.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQ
                     IRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEEDAG
                     DEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAM
                     RLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPM
                     RLSYIEKKKGRQTTHIVFSFRDITSMTTG"
                     /name="repE"
     gene            complement(15653..16799)
                     /locus_tag="LQR15_25595"
                     /pseudo=""
     CDS             complement(15653..16799)
                     /locus_tag="LQR15_25595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEc52 family transposase"
                     /name="IS3-like element ISEc52 family transposase"
     Typing          14650..15036
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.205"
                     /coverage="100.0"
                     /evalue="1.27e-127"
ORIGIN
        1 aaagtcagcg gtgggtatcg tattgaaaac ccgaccccct attatgtcac tgttattggt
       61 ctgggaggaa gtgaaaagca ggcagaggaa ggtgagtttg aaaccgtgat gctgtctccc
      121 gttcagagca gacagtaaaa tcggcaaatt ataatacccc ttatctgtct tatattaacg
      181 actatggtgg tcgcccggta ctgtagttta tctgtaatgg cagccgttgc tctgtgaaaa
      241 aagagaaata atgtaccgca ataacggtta aatgcgggtg ggatattatg gttgtgaata
      301 aaacaacagc agtactgtat cttattgcac tgtcgctgag tggtttcatc catactttcc
      361 tgcggggaag agcggggtat atacgatgac gtctttactg cagatgagtt gcatcattac
      421 cggataaatg aacggggggg acgcacggaa gcctggcagt cagtggtgca ctgctgtcct
      481 caccctgcac gctggtgagt aatgaggtgc gtaagcctcc ggccggagaa tcactctgcg
      541 gcagccggag ctcctctgat gctgaggctg gcaggatgtg gggacggtgg tgcacttctg
      601 cccggaaaaa cggggcgttg cgatgacagt ctccggctca ctggtaaccg gtcacggaac
      661 cggaagtgct ttacttcctg accgtaagct atccggctgt gaccatcttg ttatacatga
      721 tggtgatacc tttttactgt gccggcctga ccggcggcag gaggatatgc tggcagcctg
      781 gaggaaaggg cggcacagga gggtgagtat tctgatgccg gagcaatccg gccatgctgc
      841 gtctgagcat aaaatatgag taagggaatg tgatgataaa aagcacaggc gctcttttaa
      901 ctgtttgccg cactgtctgc cggacaggca atagcctcag atgtggcatt cagggtaatc
      961 tgcttgacag accctgccat gtgtccggtg acagtctgaa taaacatgtc gtcttcaaaa
     1021 cccgggcgtc cagggatttc tggtatccgc ccggacgttc gccgacagag tcgtttgtca
     1081 tcaggctgga aaactgccat gcaacagcag ttggcaaaat tgtgaccctg acctttaagg
     1141 gaacggaaga ggcggccccc cgggccatct gaaggtaacc ggagtgaatg ccggccggtt
     1201 aggcattgca ctgctggaca ccgatggcag cagtctgctg aaacccggca cctcccataa
     1261 caaaggccag ggagaaaagg ttacggaaac agtcttgagc ttcctttcgg cgcgtatgtt
     1321 tgtggcaacg ccggaagccc tgcggacgaa gagtgtggta cccggtgatt atgaagcaac
     1381 agccacgttt gaattaacat atcgttagaa aaaattttgt acaggatatt tcagatgaaa
     1441 aagataagag gtttgtgtct tccggtaata ctgggggcag tgttaatgtc tcagcatgca
     1501 catgcagctg ataatctgac ctttaaagga aaactgatta ttcctgcctg tactgtacaa
     1561 aatgctgaag ttaactgggg tgatattgaa attcagaagc tggtacagag tggcggaaat
     1621 cagaaagact ttactgtcca gaggacatgt ccttatcatt tgggaacaat gaaaggttac
     1681 gatatctaca tcggcagcga cttataacaa gggaattata gttaagggta cctcatccgg
     1741 accgatgatg gattgcttat ttatctgtac aatcgtcatc aaaatggcag tatcggtgat
     1801 gctataactc tggggaccca ttcacaccaa gcatgtctca ggtcaggttc cggccagaaa
     1861 catttctctc tatgcaaaac ttggatataa aggagatata cagaatttgc gggcgggaac
     1921 attttctgca acggcaacgc tggttgcatc atattcgtaa tgctatcagt taaaatacgc
     1981 cgattttata tctcataaaa taaaatattt tctgtaccgc tctccggagg gggaatggct
     2041 cgtttatcat tatttatatc gttgcttctg acatcggtcg ctgtatggct gatgtgcaga
     2101 ttaacatcag gggaaatgtt tatatccccc catgcacatt aataacgggc agaatattgt
     2161 tgtcgatttt gggaatatta atcctgagca cgtggacaac tcacgtggtg aaatcacaaa
     2221 aaaccataag catatcctgt acgtataaga ggctcaccct ggataaaggt cacaggtaat
     2281 gcaatggctg ggcagactaa tgtactggca acaaatatag ccaattttgg tatagcgttg
     2341 tatcagggaa aaggaatgtc aacacctctt acattaggta atggttcagg aaatggttac
     2401 agagtgacag caggtctgga cacagcacgt tcaacgttca ccttacttca gtgccctttc
     2461 gtaatggcag caggacactg aatggcgggg atttccggac cacggccagt atgagcatga
     2521 tttataactg agtcatacct aaatgaataa ctgtaattac ggaagtgatt tctgatgaaa
     2581 aaatggttcc cagctttgtt attttccttg tgtgtgtctg gtgagtcctc tgcatggaat
     2641 aatattgtct tttactccct tggagacgtt aaactcttat cagggaggga atgtggtgat
     2701 tactcaaagg ccacaattta taacttcgtg gcgcccgggc attgctacgg taacctggaa
     2761 tcagtgtaat ggtctgagtt cgctgatggc tcctgggtta ctacagggag tatattgcgt
     2821 gggtagttcc ccaaaaaggt tatgaccaaa aatggatatc ccttatttat tgaggttcat
     2881 aataaaggta gctggagtga ggagaatact ggtgacaatg acagctattt tttttctcaa
     2941 ggggtataag tgggatgagc gggcctttga tacagctaat ttgtgtcaga aaccaggaga
     3001 aacaatccgt ctgactgaga aatttgacga tattattttt aaagtcgccc tacctgcaga
     3061 tcttccttta ggggattatt ctgttacaat tccatacact tccggcatac agcgtcattt
     3121 cgcgagttac ttgggggccc gttttaaaat cccatacaat gtggccaaaa cctcccaaga
     3181 gagaatgaaa tgttattctt atttaagaat atcggcggat gccgtccttc tgcacagtct
     3241 ctggaaataa agcatggtga tctgtataat agcgctaata atcattatgc ggctcagact
     3301 ctttctgtgt cttgcgatgt gcctgcaaat attcgtttta tgctgttaag aaatacaact
     3361 ccgacataca gccatggtaa gaaattttcg gttggtctgg ggcatggctg gggactccat
     3421 tgtttcagtt aacggggtgg acacaggaga ggacaacgat gagatggtac aaagcaggta
     3481 cacaaaaacc tgaccatcgc agtcgcctct atggtgaatc ttcaaagata caaccaggag
     3541 tactatctgg ttcagcaaac gctgctcatg atattgccat aaatggttta tccggagccg
     3601 gatagagtgt gtggatatct gggatgcccg ggaagtcacc tttcagccac ttcatttatg
     3661 gattatacgc ggcctgcact gagttacgtc catgtagctc atctgacgtt tcagccgctt
     3721 tatctcgtgc tgttctggtc tcaatacttc catgccgttg caattacctc ttaaaccatt
     3781 ccttaccttt tcatgtcttc gataagaaat cttcatcatg catgatcgat tttgtcgatc
     3841 gattcgaatc gaattttctc tttttaccct gtcttttgca tgtgcgtatt accgtgaagg
     3901 agatcggtga gtaacatcga tggagatcgg ttcgtgtcac tttcacagaa ccgtttttaa
     3961 attaccttca ctgatctcct tcggtcaacg gagattgtat tttccgcatt gattctcctt
     4021 taagttcgat cttgatactg ccatgaacca gtcgatctag gatggcatcc gcatgtgtgg
     4081 agtctccgat cattttgtac cagttttcca ccggcaactg gctcactacg atgattgagc
     4141 ctcgttggta catcagatcc actatttcca gcaggtcgct acgctgttct gatgagagag
     4201 gttccagccc ccagtcatcc agaagcagca gatcgctatt attcagcctg gtcaaaagtt
     4261 tgctgtatct tccatcagca tgcccctgat agcactgttc catcagcgct ttaaggcgat
     4321 aatagtagac cttgtatccc tgtcggcagg cattatgacc aagtgcacat gccaggaacg
     4381 ttttaccgct gccggtggcc ccggtcagta aaatattttg tttcagggtt aaccagtttc
     4441 cctgactgag tgaacggatg agggccctgt ccagccctct attgttacga taatccagct
     4501 ttgataactc agcattaagt ctgaaccgtg catgtttgat cagacgctct gccttcctgt
     4561 tttcacggca ggttagttct tctgctgtca gtaatgacag gcgttcttcg aagcccagct
     4621 cctggtatgt gcccggttga gcaagttgct ttttaagcgc atcacggaag ccggtgagtt
     4681 taagtgcggt cagttgttcg taaagatgat tcatcattgg atcccgtatc agtggtaata
     4741 ctcactgccg cgtacgtttt cgtgttccat cgtggataac agatctggtt ttggatcctg
     4801 aacaggttgt ttatccagac ctttttccag gatcgattta atacctgaca gacgccatac
     4861 ctttgttttc agagctcttg cacatgctgc attaagtctg gctttactgt attttttatg
     4921 aaggttcagg agtccaaggc agaagcgata gctttgttcc ggatgtggac gagagttcag
     4981 tatatgaagc acataactat gagtttcact gcctatgtgc cccgcccatt ccagaagacg
     5041 ctctggcgtc caggtggcat gctgtcgatg agcttcaggc atgtgctcgt tgcgggtact
     5101 gtagccataa gtacgcttgc gcgggtgcac agcaacctcc tgcccctgat tgaagagtct
     5161 taccagttct ccggagatcc atgcttccag ttgctggcct aacagcgaac atggaaccga
     5221 gtagtaatgt ttgtcgattt ccacgtggta atcggcatga actctgactt tcttcaccag
     5281 ggtgtaactg taactggctt caggaagagg cttcagtgcg ggtttatcaa gctggatgaa
     5341 gagttctgca cgtgaataac ccaacttctg cattattttg ttattcagtc tttccagcaa
     5401 ctcccgaatg cgctgattaa gcgatgcaag gctgtagaag atctcatgcc tgattcgggc
     5461 catgatccag cgttcaacaa cctgaacgcc aacttcagct ttggctttat ctttcggttt
     5521 acgtggccgc gcaggcaaaa ctgcgacatt ataatgctca agcatctgct ggtaggtagg
     5581 gttaacgtca ggatcatact tacatgccct ggatgtggcg cttttcagat tgtccggaac
     5641 aacaagttca ggaacgccac ccaaccactg gaagcagcga acatgactca tcacccagtc
     5701 ttcaagctgc tgagaccagg tggcctctgc ccatgtgtaa cttgatgccc cgagaacagc
     5761 tacgatgacc tgagcagttc ttatttctcc ggtctcaggg tcggtaacgc caacggtagg
     5821 tccacagtaa tcaacgaaaa gtttttcgcc agctttatgt acctgacgca ttgatggtga
     5881 agtggttttg agccattcac ggtacatccg gcagtaatgg ttatagctgt aaaaaccgcc
     5941 tggattacgc tcacagtatt cttcccagag tagctgcagc gtcacgcatt tattacgcag
     6001 ttcccggtgt actgtagccc agtcaggcag agagtgcttc ttcatcttaa cctgggtctg
     6061 aaggaacgca tgttttagtt ttgtatcatc ccatcctgta ggtaagggcc actgctttat
     6121 gccaagttga gccgcccgat tagcatatct ggatacaacg gaaggggaga ttgcaagact
     6181 acgaccaatt tgtcgatggc tgagtccaac accgtattta agcctaagaa tttctttaag
     6241 ttttctcata gaaattggaa ctgttggcat aggtatcctt taccggaatg gcaaaagata
     6301 cagatcaaca cacctgtgaa gttccaataa cattgatgga gatcactgaa taacaaaatg
     6361 agtcaaaagt gatctccatc gatgttattc agcgatctgt tcaaatgtta ttacccgatc
     6421 tcgatggaag ttattgagtg atctcctttc atgaaaatac gcaatcgctg tggaacatca
     6481 ccccgacggg cttaccacgg gtttcccatg ccatttccag tgctttcatg gtaagcctgc
     6541 tgtccggcga gaacgacatg gcccagcctg acctgcccct ctttcctgcg caaccacgct
     6601 accagcgagt caattccacc aatacggcga aacagttcat cgctgttaaa aaacggctgc
     6661 aacgcctcat ttgttgccat agtttgctcg gaaacaacga ggccgtcgtc catgtgctcg
     6721 attaactcac gcggtaccgg ctccataata aatttacggc cagcctccac cagctttctg
     6781 acttcctgat ccactttgaa tgtggcgacg ccaagctctt tttgtacaaa gggagtaatt
     6841 acggctttca catcacacct ttcatcactg attgggcttt atctgctgcc cggcattctc
     6901 tgtttaagca caaccatttc ctgacggcat aacacagcaa tagcggtcct ggcaccaatt
     6961 tgcttaccag ccaggtattg ctttacctcg cggcgactca cgccatcaag aagcatcttt
     7021 aacgcttcac gggacaattt gttgtatttg cgtgccatta atctactccg cagaaccata
     7081 caatctacgt aacgtgtcgg cgacagaaga tacagatatc tctccggtcg cagcccctac
     7141 ggtaaggtct gccagttcag gtgaatcaaa tacctgcacc ccgttacggc gtagaaataa
     7201 cagcgcactg tttagcgcgg tacgcttatt ggcatcattg aatatatgcc ctctcgctgt
     7261 agccaccagg taggtggcgg agacttcgaa aaggtcggtg atctcttcgt aggcaactct
     7321 ggcctgaact ctcccgataa tggcctctgc cctgcccgga tcagacattc ccggcaggcc
     7381 gccgtagcgg tttatattcg catcatgaag cgcaataagt tcttccggtg atatatgcct
     7441 cattatcggt taaccagttc cttgttggtg gagtccaggg tgtcaaacag ggatgcaaat
     7501 tcagcatcca gcgccgcttt tttgtaggct tcgaaagtag ccttgctgac aattactgct
     7561 ggctcacggc ctctgcgggt gatttcaacc tcttccccgg cctcaacatt gttgagcact
     7621 tcagaaaggt tgccgcgcgc ggtacggaag ttaatggatt gcataaacac ctcgtgtact
     7681 cgttatgtgt acacaattat aaacttcaca ggcataaagc accagcactt tgcggcttaa
     7741 caaacctcta ggcaggtcat tcgtagccta atgtccgaac tgctaaagca tccaagttgc
     7801 tgtagaatca ccgccaatta cataagcctg aaataagtgg atgaaaatga caagtattca
     7861 acaacgtgca gagcttcatc gtcaaatctg gcaaattgct aacgatgtca ggggttcggt
     7921 cgatggatgg gattttaagc aatacgttct gggcgcactt ttctaccgtt ttatcagcga
     7981 aaatttttcc agttatattg aagccggtga tgacagtatc tgttatgcga aactggatga
     8041 cagcgtaatt actgatgaca ttaaagacga tgccatcaaa accaaaggct acttcatcta
     8101 cccaagccag cttttctgca acgtagctgc gaaagcaaat accaatgaca gattgaatgc
     8161 agatttaaac agcatcttcg ttgctatcga aagttctgct tacggttatc cttcagaagc
     8221 tgacatcaaa ggtttgtttg ctgatttcga taccaccagt aaccgcctgg gtaacaccgt
     8281 taaagataaa aatgcccgcc tggctgcggt tctgaaaggg gttgaagggt taaaacttgg
     8341 tgacttcaac gaacatcaga ttgacctgtt cggtgatgcc tatgagttcc tgatttctaa
     8401 ctatgcggca aatgccggta agtcaggcgg tgagttcttt acaccgcagc acgtctccaa
     8461 gctgattgca caactggcta tgcacgggca gaccagcgtt aacaaaatct acgacccggc
     8521 agcgggttcc ggctcactgt tgttgcaggc gaaaaaacag tttgataacc atatcatcga
     8581 agaaggtttt tttggtcagg aaatcaacca tacgacctat aacctggcgc gtatgaacat
     8641 gtttttgcac aacatcaact acgacaagtt tgatatcaag ctgggcaata cgctgactga
     8701 accgcacttc agagatgaaa aaccgtttga tgccatcgtt tctaacccgc cgtattcggt
     8761 gaaatggatt ggcagcgatg acccgacgct gattaacgat gaacgttttg ccccggctgg
     8821 cgttctggcc cccaaatcca aagctgactt tgcgtttgta ttacatgcgc tgaactatct
     8881 ttctgccaaa ggtcgtgctg cgattgtctg cttcccgggc attttttacc gtggcggcgc
     8941 ggagcagaaa atccgtcagt atctggttga caataactat gtcgaaaccg tgatttcact
     9001 cgcaccgaac ctgttctttg gcaccaccat tgccgtcaat attctggtgt tgtctaaaca
     9061 taaaacggat accaaagttc agtttattga tgccagcgaa ctattcaaaa aagagaccaa
     9121 caacaatatc ctgaccgatg cccatatcga acagatggtg atgctgccaa cttactgatt
     9181 tagtgtatga tggtgttttt gaggtgctcc tgtggcttct gtttctatca gctgtccctc
     9241 ctgttcagct actgacgggg tggtgcgtaa cggcaaaagc actgccggac atcagcgcta
     9301 tctctgctct cactgccgta aaacatggca actgcagttc acttacaccg cttctcaacc
     9361 cggtacgcac cagaaaatca ttgatatggc catgaatggc gttggatgcc gggcaacagc
     9421 ccgcattatg ggcgttggcc tcaacacgat tttacgtcac ttaaaaaact caggccgcag
     9481 tcggtaacct cgcgcataca gccgggcagt gacgtcatcg tctgcgcgga aatggacgaa
     9541 cagtggggat acgtcggggc taaatcgcgc cagcgctggc tgttttacgc gtatgacagg
     9601 ctccggaaga cggttgttgc gcacgtattc ggtgaacgca ctatggcgac gctggggcgt
     9661 cttatgagcc tgctgtcacc ctttgacgtg gtgatatgga tgacggatgg ctggccgctg
     9721 tatgaatccc gcctgaaagg aaagctgcac gtaatcagca agcgttacac tcagcgaatt
     9781 gagcggcata acctgaatct gaggcagcac ctggcacggc tgggacggaa gtcgctgtcg
     9841 ttctcaaaat cggtggagct gcatgacaaa gtcatcgggc attatctgaa cataaaacac
     9901 tatcagtaag ttggagtcat tacctgtgtt actaaccgtc tgaggcgaag gtgactatgg
     9961 gtttacgctg acactcaggc aaccaagaat tgtttatcgg atgtgctccg gcatacgtaa
    10021 atcctacacc ggagctaagg agggattact tctgaaggtg cagctccttc agatttgttt
    10081 caaagtaatc aacataaatt cgttcatttt tgggcttcat tatcagctga ataccgttgg
    10141 gtacgggcgg acatgaggcc cggtaggtaa acatctcatc ttggatattc cggagcgtat
    10201 aagccagttg ctcttcttct gcccttccgg acacccttat gccggataat tccttctcaa
    10261 cgtacttttt cagcttctcg cttcttttca tactgctgcg attatccaga aactgaagca
    10321 agaaatagcg gatgaccggc agtgtgaaca ccacatagaa gaggatctca ttcagcccgg
    10381 atttcatgac gatgccgtaa acaagcatcg cgacaggcga gacaataaaa gcggaaagat
    10441 aaaatacgtg cagaacctcc ctgagcgatt tgtcccagcc gagatttttt ccgtggcaaa
    10501 ggagcgccat tacggcctgc ggcgcgtcat acaccttact gacgtaccac ccctcttcgc
    10561 caaatcgctt tcgtgctttt tccgggctgt ctctaaaata tgcagcttcc cggatgatgt
    10621 catcccgtgg gatctcctcc accttcagtt cattacgccg gatgccaagt acccggcagt
    10681 cgtacatttc ctggattgag gctgccttcc tgcgcagagc cgagatgtgt ccactgataa
    10741 caatgttaaa ggtaagcacc aggagtccat ataaccccaa cagcgaagac aacaactctg
    10801 aatcgacaaa ttcccggctc cggttgtata cggtaacgaa agaaagcagg agcggtacga
    10861 tgatgctgaa gagaaaattc agtctgttcc agttttttac cctgtcgtag acacgggcct
    10921 gcgcatacag taaatccatg ttttctctgg tcgactggtt tgtgtaaatg gcattcatga
    10981 ttcacccgta aacaggaaag aatggcccga acacatcgcg ccatttattg atggattttt
    11041 catactcttt attattttca aaccatctcg cctccgatac cttttgcgca tcgagataac
    11101 atctgtccga tatcgcctta cgtgcctcgg ctgaaagtga gttgatatca ccctgtatgc
    11161 ctttgggatc gttgacagag taccgcacgg attgaccaag gtggcggaaa agcgcttcca
    11221 gctccatgtc aacaaacgat gagcaggatg tcctgccagc gtaatagtcc agaatcagcg
    11281 tttccagcag gtaggaactc atggatggca tcgtcggtcg ccgctgccag tatttgactg
    11341 ctctgatgac attgagcaca ttgccgttat tctgcacatt gatagtagtg actctgtccc
    11401 tgtctttacg ggggtcggta aacttccagt ggccgttgcc atcggggatc aggtagtaag
    11461 tccgtccaaa ggcatcttcg ctggtaataa agcaggggac gatgtcaaaa ttccagtcct
    11521 tgctgaccag tttcagcgtg acagcttcct ggttacgcct gatatcagcc tgggcgtact
    11581 gggcaatgtc ctgcaggcgg tttttaaagg cattcagaat tctgacggag cagacggtgt
    11641 cagctccgga atggcggtaa ctgtgcagac gtgacccctc tccggaggag gttacagtta
    11701 tccggtcact caggatggta taggtggcac cttgcccggt taagccaaac atcagatcga
    11761 tatcatcaag cggacggatt ttggttcttc tggcaaagga gccaaaggca atatggatcg
    11821 ctggaaaact caccggaaat ttatcgtcct tctcaaaatc attcatctta ccgataagcc
    11881 agtcgcgact tgcacgcgcg tcatcggtat ctgccttttt gagattcacg gtatctttca
    11941 taaattcgtt aaaggcagct attactgtgg tcgccatgtt cagtccttta attatttatt
    12001 gcaaaaggcg cggggctctg tcgtacatct gaacattcca gtgcccggga agagtcggta
    12061 cagtttatta ttagtgccgc aagttcacta ccgtctcgct ctctgcaagg gcatataatt
    12121 tacatgggaa atatgagcct cgttctttca ttgataatta tgcaaagtat ttcagttatt
    12181 aatgccagat aagcaataat gcaattaagt tcaaaatata tcattagtat tgcatcatca
    12241 gcacaaatcc ttcttcccct ctccagagat ccgaaaaaag taagttacgg atcttcctct
    12301 ccctccgcac agcgttacat cccgtcagca cagcatgtag tgcctcatac agttgccaat
    12361 ggcactatat gttgtgttgt atctctggac tgtgatgcgc cgcgcagggg cggaaaacag
    12421 cgatatgatg attttctcag cgttgtacac ttccggaaag tcgtttattc aaataaagtc
    12481 ggatccatac gaaacgggaa tgcggtaatt acgctttgtt tttataagtc agattttaat
    12541 ttttattggt taacataacg aaaggtaaaa tacataaggc ttactaaaag ccagataaca
    12601 gtatgcgtat ttgcgcgctg atttttgcgg cataagaata tatactgata tgtatacccg
    12661 aagtatgtca aaaagaggtg tgctatgaag cagcgtatta cagtgacagt tgacagcgac
    12721 agctatcagt tgctcaaggc atatgatgtc aatatctccg gtctggtaag cacaaccatg
    12781 cagaatgaag cccgtcgtct gcgtgccgaa cgctggaaag cggaaaatca ggaagggatg
    12841 gctgaggtcg cccggtttat tgaaatgaac ggctcttttg ctgacgagaa cagggactgg
    12901 tgaaatgcag tttaaggttt acacctataa aagagagagc cgttatcgtc tgtttgtgga
    12961 tgtacagagt gatattattg acacgcccgg gcgacggatg gtgatccccc tggccagtgc
    13021 acgtctgctg tcagataaag tctcccgtga actttacccg gtggtgcata tcggggatga
    13081 aagctggcgc atgatgacca ccgatatggc cagtgtgccg gtctccgtta tcggggaaga
    13141 agtggctgat ctcagccacc gcgaaaatga catcaaaaac gccattaacc tgatgttctg
    13201 gggaatataa atgtcaggct ccgttataca cagccagtct gcagtcatgg taccggcagt
    13261 gtattctgcc gggcagcctg catcgctgcc tgttgccatt gattatccgg cagctctggc
    13321 acttcgccag atgtcgatgg tccatgatga actgccaaaa tatctgctgg ctccggaagt
    13381 gagtgccctg ctccattacg tcccggatct gcaccgcaag atgctgctgg ccacactgtg
    13441 gaacaccgga gcacgcatta atgaagcact ggcgctgacg cggggggatt tttcgcttgc
    13501 gcctccgtat ccgtttgtgc agcttgcgac cctgaaacaa cggaccgaaa aagctgccag
    13561 gacggcgggg agaatgcccg ccggtcagca gactcaccgg ctggttccgc tctctgactc
    13621 ctggtacgtc agccagctgc agacgatggt ggcaacactg aaaataccca tggagcggcg
    13681 taaccgtcgc acaggaagga cagagaaagc gcggatctgg gaagtgacgg acagaacggt
    13741 caggacctgg attggggagg cggttgccgc cgctgctgct gacggtgtga cgttctctgt
    13801 tccggtcaca ccacatacgt tccgccattc ctatgcgatg cacatgctgt atgccggtat
    13861 accgctgaaa gttctgcaaa gcctgatggg acataagtcc atcagttcaa cggaagtcta
    13921 cacgaaggtt tttgcgctgg atgtggctgc ccggcaccgg gtgcagtttg cgatgccgga
    13981 gtctgatgcg gttgcgatgc tgaaacaatt atcctgagaa taaatgcctt ggcctttata
    14041 tggaaatgtg gaactgagtg gatatgctgt ttttgtctgt taaacagaga agctggctgt
    14101 tatccactga gaagcgaacg aaacagtcgg gaaaatctcc cattatcgta gagatccgca
    14161 ttattaatct caggagcctg tgtagcgttt ataggaagta gtgttctgtc atgatgcctg
    14221 caagcggtaa cgaaaacgat ttgaatatgc cttcaggaac aatagaaatc ttcgtgtggt
    14281 gttacgttga agtggagcgg attatgtcag caatggacag aacaacctaa tgaacacaga
    14341 accatgatgt ggtctgtcct tttacagcca gtagtgctcg ccgcagtcga gcgacagggc
    14401 gaagccctcg agtgagcgag gaagcaccag ggaacagcac ttatatattc tgcttacaca
    14461 cgatgcctga aaaaacttcc cttggggtta tccacttatc cacggggata tttttataat
    14521 tatttttttt atagttttta gatcttcttt tttagagcgc cttgtaggcc tttatccatg
    14581 ctggttctag agaaggtgtt gtgacaaatt gccctttcag tgtgacaaat caccctcaaa
    14641 tgacagtcct gtctgtgaca aattgccctt aaccctgtga caaattgccc tcagaagaag
    14701 ctgtttttca caaagttatc cctgcttatt gactcttttt tatttagtgt gacaatctaa
    14761 aaacttgtca cacttcacat ggatctgtca tggcggaaac agcggttatc aatcacaaga
    14821 aacgtaaaaa tagcccgcga atcgtccagt caaacgacct cactgaggcg gcatatagtc
    14881 tctcccggga tcaaaaacgt atgctgtatc tgttcgttga ccagatcaga aaatctgatg
    14941 gcaccctaca ggaacatgac ggtatctgcg agatccatgt tgctaaatat gctgaaatat
    15001 tcggattgac ctctgcggaa gccagtaagg atatacggca ggcattgaag agtttcgcgg
    15061 ggaaggaagt ggttttttat cgccctgaag aggatgccgg cgatgaaaaa ggctatgaat
    15121 cttttccctg gtttatcaaa cgtgcgcaca gtccatccag agggctttac agtgtacata
    15181 tcaacccata tctcattccc ttctttatcg ggttacagaa ccggtttacg cagtttcggc
    15241 ttagtgaaac aaaagaaatc accaatccgt atgccatgcg tttatacgaa tccctgtgtc
    15301 agtatcgtaa gccggatggc tcaggcatcg tctctctgaa aatcgactgg atcatagagc
    15361 gttaccagct gcctcaaagt taccagcgta tgcctgactt ccgccgccgc ttcctgcagg
    15421 tctgtgttaa tgagatcaac agcagaactc caatgcgcct ctcatacatt gagaaaaaga
    15481 aaggccgcca gacgactcat atcgtatttt ccttccgcga tatcacttcc atgacgacag
    15541 gatagtctga gggttatctg tcacagattt gagggtggtt cgtcacattt gttctgacct
    15601 actgagggta atttgtcaca gtttgaagtg gtcaacaaaa actggccacg agttagagtt
    15661 ttttccagta tcgattttcc gattcgtttg gtggtaaccc accattatat tcgtgcggtc
    15721 ttagtgcgct gtaatatcca acgatatagt ccgttattgc gtgagctgca tcgctgaagc
    15781 ttacatagcc cgtcgccggc acccattcgt tcttcagact cctgaagaag cgctccattg
    15841 ggctgttatc ccagcagttt ccacgccgac tcatactctg cctgatccgg tatctccaca
    15901 gtaactgccg gaactgcctg ctcgtataat gactgccttg atcgctgtgg aacatcaccc
    15961 gacgggctta ccacgggttt cccatgccat ttccagtgct ttcatggtaa gcctgctgtc
    16021 cggcgagaac gacatggccc agcccactgg ttttcttgcg aacaggtcga gaacaacggc
    16081 gaggtacgcc cagcgcttac ccgtccagat ataggtcaca tcaccgcacc acacctgatt
    16141 tggctcggtc acggcgaact gccgttcaag gtagttaggg atagcaacat gttcatgacc
    16201 accacgttta taccggtaag tcggctgctg acagctgacc agccccagct ctttcatgag
    16261 tctgccagca agccagcgcc ccatctggta gcctctctgg gttgccattg tggcgatgct
    16321 tcttgctccg gcagagccgt ggctgatgcc atgcagttca agtacctggc tgcgtaatac
    16381 agcccgtctg ccgtctggct tttcaggacg gtttttccag tatttgtagc tgctgcgatg
    16441 gaccccgaac acatggcaga gagtggccac aggataacgc gccctgagtt tcccgattat
    16501 cgagaactgt tcagggagtc tgacatcaag agcgcggtag ccttttttaa tatttcattt
    16561 tccatttcaa tacgttgtag ctttttcctg agctcacgga tttcaatttg ttccggggta
    16621 ataggggagg cttttggtgt ttttccctgc cgctcatcac gtaattgttt cacccatcgc
    16681 gtcattgtgg aaaggccgac atccatagcg ctggctgcat ctgccacggt gtaattctgg
    16741 tcaacgacca gttgagcgga ttcgcgttta aactctgcgc tgaaatttct ttttttcatt
    16801 atggcacctg tgttgttctg aggtgagcat atcacctctg ttcaggtggc caaattcagt
    16861 aaaccacttc agttttgctg tttccttcag cctgcatgga ttttctcata ctttttgaac
    16921 tgtaattttt aaggaagcca aatttgaggg cagtttgtca cagttgattt ccttctcttt
    16981 cccttcgtca tgtgacctga tatcgggggt tagttcgtca tcattgatga gggttgatta
    17041 tcacagttta ttactctgaa ttggctatcc gcgtgtgtac ctctacctgg agtttttccc
    17101 acggtggata tttcttcttg cgctgagcgt aagagctatc tgacagaaca gttcttcttt
    17161 gcttcctcgc cagttcgctc gctatgctcg gttacacggc tgcggcgagc gctagtgata
    17221 ataagtgact gaggtatgtg ctcttcttat ctccttttgt agtgttgctc ttattttaaa
    17281 caactttgcg gttttttgat gactttgcga ttttgttgtt gctttgcagt aaattgcaag
    17341 atttaataaa aaaacgcaaa gcaatgatta aaggatgttc agaatgaaac tcatggaaac
    17401 acttaaccag tgcataaacg ctggtcatga aatgacgaag gctatcgcca ttgcacagtt
    17461 taatgatgac agcccggaag cgaggaaaat aacccggcgc tggagaatag gtgaagcagc
    17521 ggatttagtt ggggtttctt ctcaggctat cagagatgcc gagaaagcag ggcgactacc
    17581 gcacccggat atggaaattc gaggacgggt tgagcaacgt gttggttata caattgaaca
    17641 aattaatcat atgcgtgatg tgtttggtac gcgattgcga cgtgctgaag acgtatttcc
    17701 accggtgatc ggggttgctg cccataaagg tggcgtttac aaaacctcag tttctgttca
    17761 tcttgctcag gatctggctc tgaaggggct acgtgttttg ctcgtggaag gtaacgaccc
    17821 ccagggaaca gcctcaatgt atcacggatg ggtaccagat cttcatattc atgcagaaga
    17881 cactctcctg cctttctatc ttggggaaaa ggacgatgtc acttatgcaa taaagcccac
    17941 ttgctggcct gggcttgaca ttattccttc ctgtctggct ctgcaccgta ttgaaactga
    18001 gttaatgggc aaatttgatg aaggtaaact gcccaccgat ccacacctga tgctccgact
    18061 ggccattgaa actgttgctc atgactatga tgtcatagtt attgacagcg cgcctaacct
    18121 gggtatcggc acgattaatg tcgtatgtgc tgctgatgtg ctgattgttc ccacgcctgc
    18181 tgagttgttt gactacacct ccgcactgca gtttttcgat atgcttcgtg atctgctcaa
    18241 gaacgttgat cttaaagggt tcgagcctga tgtacgtatt ttgc
//
