LOCUS       CP088532               21318 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain E16EC0601 plasmid pE16EC0601-3, complete
            sequence.
ACCESSION   CP088532
VERSION     CP088532.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391648
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21318)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21318)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 122x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 11:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,262
            CDSs (total)                      :: 5,142
            Genes (coding)                    :: 4,944
            CDSs (with protein)               :: 4,944
            Genes (RNA)                       :: 120
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 72 of 198
            Pseudo Genes (incomplete)         :: 138 of 198
            Pseudo Genes (internal stop)      :: 32 of 198
            Pseudo Genes (multiple problems)  :: 40 of 198
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..21318
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="E16EC0601"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pE16EC0601-3"
                     /geo_loc_name="South Korea"
                     /lat_lon="34.87 N 126.99 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            join(21316..21318,1..380)
                     /locus_tag="LQT69_26065"
                     /pseudo=""
     CDS             join(21316..21318,1..380)
                     /locus_tag="LQT69_26065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(391..1232)
                     /locus_tag="LQT69_26070"
                     /pseudo=""
     CDS             complement(391..1232)
                     /locus_tag="LQT69_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /name="DUF4198 domain-containing protein"
     gene            complement(1239..1850)
                     /locus_tag="LQT69_26075"
                     /pseudo=""
     CDS             complement(1239..1850)
                     /locus_tag="LQT69_26075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555799.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /name="TonB-dependent receptor"
     gene            1913..2617
                     /locus_tag="LQT69_26080"
     CDS             1913..2617
                     /locus_tag="LQT69_26080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UGF60825.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(2670..2906)
                     /locus_tag="LQT69_26085"
                     /pseudo=""
     CDS             complement(2670..2906)
                     /locus_tag="LQT69_26085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132006.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3330 domain-containing protein"
                     /name="DUF3330 domain-containing protein"
     gene            complement(3109..4122)
                     /gene="intI1"
                     /locus_tag="LQT69_26090"
     CDS             complement(3109..4122)
                     /gene="intI1"
                     /locus_tag="LQT69_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="UGF60826.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     ARG             4206..4720
                     /name="dfrA17"
                     /gene="dfrA17"
                     /gene_name="trimethoprim resistant dihydrofolate reductase
                     dfr"
                     /tool="rgi"
                     /drug_class="diaminopyrimidine antibiotic"
                     /identity="95.83"
                     /coverage="108.92"
     ARG             4281..4705
                     /name="dfrA17"
                     /gene="dfrA17"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="97.89"
                     /coverage="90.45"
     gene            4883..5671
                     /locus_tag="LQT69_26100"
     CDS             4883..5671
                     /locus_tag="LQT69_26100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="UGF60827.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKPD
                     SDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYPAR
                     RELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKEHFS
                     KALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPAEHRP
                     LICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
                     /name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
     gene            5877..6224
                     /locus_tag="LQT69_26105"
     CDS             5877..6224
                     /locus_tag="LQT69_26105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="UGF60828.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            6218..7057
                     /gene="sul1"
                     /locus_tag="LQT69_26110"
     ARG             6219..7054
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7185..7388
                     /locus_tag="LQT69_26115"
     CDS             7185..7388
                     /locus_tag="LQT69_26115"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGF60834.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLGIASENGK"
                     /name="hypothetical protein"
     gene            7544..8749
                     /gene="chrA"
                     /locus_tag="LQT69_26120"
     CDS             7544..8749
                     /gene="chrA"
                     /locus_tag="LQT69_26120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="UGF60830.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRRR
                     WLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILFAL
                     GISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLVPSA
                     WGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVLAELM
                     PSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAVPGPLF
                     TFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQAALAGIN
                     AAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGAAGWLLSV
                     AL"
                     /name="chrA"
     gene            8760..9065
                     /locus_tag="LQT69_26125"
     CDS             8760..9065
                     /locus_tag="LQT69_26125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="UGF60831.1"
                     /translation="MTDKDLYGGLIRLHILHHAAEEPVFGLGIIEELRRHGYEMSAGTV
                     YPMLHGLEKKGYLTSRHERTGRRERRVYDITEQGRTALADAKTKVKELFGELVEGG"
                     /name="PadR family transcriptional regulator"
     gene            9109..9174
                     /locus_tag="LQT69_26130"
                     /pseudo=""
     CDS             9109..9174
                     /locus_tag="LQT69_26130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            9292..10056
                     /locus_tag="LQT69_26135"
     CDS             9292..10056
                     /locus_tag="LQT69_26135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="UGF60832.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHT
                     TIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFY
                     LSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQ
                     VKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIR
                     GEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(10549..11133)
                     /gene="mphR(A)"
                     /locus_tag="LQT69_26140"
     CDS             complement(10549..11133)
                     /gene="mphR(A)"
                     /locus_tag="LQT69_26140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide-binding transcriptional repressor
                     MphR(A)"
                     /protein_id="UGF60833.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAALI
                     QRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVNYL
                     ISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVDPDG
                     ELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
                     /name="mphR(A)"
     gene            complement(11133..12371)
                     /gene="mrx(A)"
                     /locus_tag="LQT69_26145"
                     /gene_synonym="mrx"
     CDS             complement(11133..12371)
                     /gene="mrx(A)"
                     /locus_tag="LQT69_26145"
                     /gene_synonym="mrx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide resistance MFS transporter Mrx(A)"
                     /protein_id="UGF60822.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWAG
                     ATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTGLI
                     ACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGAAIG
                     LLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLLRPLF
                     GIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVGARISA
                     QNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRTPPELLG
                     RVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQFATMAAA
                     ATASAPTHTEGEH"
                     /name="mrx(A)"
     gene            complement(12368..13273)
                     /locus_tag="LQT69_26150"
     CDS             complement(12368..13273)
                     /locus_tag="LQT69_26150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="UGF60823.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDD
                     GRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMV
                     IQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDV
                     DRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSE
                     ARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFA
                     LDSGNEEYLAAAKAQLAAAE"
                     /name="Mph(A) family macrolide 2'-phosphotransferase"
     gene            complement(13395..14098)
                     /locus_tag="LQT69_26155"
                     /pseudo=""
     CDS             complement(13395..14098)
                     /locus_tag="LQT69_26155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            14122..14495
                     /gene="tnpB"
                     /locus_tag="LQT69_26160"
                     /pseudo=""
     CDS             14122..14495
                     /gene="tnpB"
                     /locus_tag="LQT69_26160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624730.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase.; frameshifted; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /name="tnpB"
     gene            14544..15488
                     /locus_tag="LQT69_26165"
                     /pseudo=""
     CDS             14544..15488
                     /locus_tag="LQT69_26165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /name="IS66 family transposase"
     gene            15574..16593
                     /gene="istA"
                     /locus_tag="LQT69_26170"
                     /pseudo=""
     CDS             15574..16593
                     /gene="istA"
                     /locus_tag="LQT69_26170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /name="istA"
     gene            16590..17372
                     /gene="istB"
                     /locus_tag="LQT69_26175"
     CDS             16590..17372
                     /gene="istB"
                     /locus_tag="LQT69_26175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="UGF60824.1"
                     /translation="MMMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLE
                     HLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNE
                     NIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGV
                     MAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALT
                     SAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
                     /name="istB"
     gene            17440..18047
                     /locus_tag="LQT69_26180"
                     /pseudo=""
     CDS             17440..18047
                     /locus_tag="LQT69_26180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /name="IS66 family transposase"
     gene            complement(18110..18898)
                     /locus_tag="LQT69_26185"
                     /pseudo=""
     CDS             complement(18110..18898)
                     /locus_tag="LQT69_26185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /name="DUF4198 domain-containing protein"
     gene            complement(18905..20865)
                     /locus_tag="LQT69_26190"
                     /pseudo=""
     CDS             complement(18905..20865)
                     /locus_tag="LQT69_26190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555799.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /name="TonB-dependent receptor plug domain-containing
                     protein"
     gene            21145..21296
                     /locus_tag="LQT69_26195"
                     /pseudo=""
     CDS             21145..21296
                     /locus_tag="LQT69_26195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     ARG             5878..6221
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12372..13273)
                     /name="mph(A)"
                     /gene="mph(A)"
                     /gene_name="Mph(A) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             4884..5668
                     /name="aadA5"
                     /gene="aadA5"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12369..13273)
                     /name="mphA"
                     /gene="mphA"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(11134..12371)
                     /name="Mrx"
                     /gene="Mrx"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 ctgaaatccc tggaaagctg gctgcgtgaa aagatgaaaa ccctgtcgcg acactcagaa
       61 ctggcgaaag cgttcgcata cgccctgaac cagtggccgg cgctgacgta ctatgcagat
      121 gatggctggg ctgaggcgga caataacatc gctgaaaatg cgttgcggat ggtcagtctg
      181 ggccgcaaaa actacctgtt cttcggttcg gatcatggag gagagcgggg agcgctgctg
      241 tacagcctga tcgggacgtg caaactgaac ggagtggagc cagaaagcta cctccgctat
      301 gtccttgacg tcatagccga ctggccgata aaccgggtcg gcgaactgct ccctggcgcg
      361 tagcactgcc gactgaataa cacatccccg tcaatacggt tcttgctgca cgcttacaat
      421 ttcagggcag ggaatagtat tgttaatttc ggagaaactt aaagttgcca catcgacagt
      481 ttcatcacac aggcttttgt cctgaaaact tttcttattt tggactttcg ccagccactg
      541 tccaatatga agagaaggta ctgtgacgat accatcctca ttagttacaa aggtgagttc
      601 tgctttatga acaggatgtt tgtgctcaac tgcatgagta tgacgggatg atttcagata
      661 actgaccgag tcaagctcca tgatagctcc ggcgagcggg gacgttttat acaggacttt
      721 cagcttcaca tcttcactga aacgacttat atcggataac ggaatgattt caagctcatg
      781 ccccgttgga gactgataga gttgtgctgg catctgctgt tcaccaggaa taaaagattt
      841 cgcatattta gtgacaaact cacagtaagc cacatcattt ctgccctccc ggctgaccgg
      901 tttccatcct gaagaggttc tcgaccagta tcccggtttc atatatgttg acaaaacgta
      961 gccattatct ttgcttgcag actcagtttt atagacataa tccgtggacg ctggcttcag
     1021 tgttattgtc tctttcccgt tataaatccg gggattttca aagaaattcc ttctgtcagg
     1081 aattgtgccc tttgagggga aattatgacc ataaccaatc tctgcggtaa tgttgttctc
     1141 tgcctgttta cctgtaatcc agacatcgtg ggccaggaca tgcccgatgc tgtcagacaa
     1201 agagctaaga tataacctgt atttttcatc atgatttgtt accactgata acgggtataa
     1261 agactgacag ttctgcctga aagcggcact cctttgccat tcatggcaag cttgttgaag
     1321 gcattatcca gagccactga tgcctcaaag cctttaacac ttacaggctt ataagacagt
     1381 gaaaaggaat gtacggcata gccagcctga tggggatcgc cttttttcac atgcgtggct
     1441 gctgccgaaa gttcagcacg ccatccggca gaaactcctc catgaccaac aggtatactt
     1501 atgtcactga tgagtgtgtc aggattgccg gagcccagcc attccctgct gctggcatcc
     1561 atactttccg tgcggttata agaaagcatc cagtcaaaat aatcagactg gtaatttccc
     1621 tgcatatccc atccccagat acgggcccgg gatacattat aagaataaga acgcatccgt
     1681 ttcatatcca cgcgcgtggc aatatagttt ctggcatccg ttccgaaata tccgcctttc
     1741 aactgcagcc gatcattgcc tgtaagcagg ccgtccagtt gaatacctgc gccaatctca
     1801 cgggtaatgt tattttctgg tttcagatta aggttaggta cccagtaatg gcactgttgc
     1861 aaatagtcgg tggtgataaa cttatcatcc ccttttgctg atggagctgc acatgaaccc
     1921 attcaaaggc cggcattttc agcgtgacat cattctgtgg gccgtacgct ggtactgcaa
     1981 atacggcatc agttaccgtg agctgcagga gatgctggct gaacgcggag tgaatgtcga
     2041 tcactccacg atttaccgct gggttcagcg ttatgcgcct gaaatggaaa aacggctgcg
     2101 ctggtactgg cgtaaccctt ccgatctttg cccgtggcac atggatgaaa cctacgtgaa
     2161 ggtcaatggc cgctgggcgt atctgtaccg ggccgtcgac agccggggcc gcactgtcga
     2221 tttttatctc tcctcccgtc gtaacagcaa agctgcatac cggtttctgg gtaaaatcct
     2281 caacaacgtg aagaagtggc agatcccacg attcatcaac acggataaag cgcccgccta
     2341 tggtcgcgcg cttgctctgc tcaaacgcga aggccggtgc ccgtctgacg ttgaacaccg
     2401 acagattaag taccggaaca acgtgattga atgcgatcat ggcaaactga aacggataat
     2461 caacgccacg ctgggattta aatccatgaa gacggcttac gccaccatca aaggtattga
     2521 ggtgatgcgt gcactacgca aaggccaggc ctcagcattt tattatggtg atcccctggg
     2581 cgaaatgcgc ctggtaagca gagtttttga aatgtaaggc ctttgaataa gacaaaaggc
     2641 tgcctcatcg ctaactttgc aacagtgccc tcggcccctt ccggcgtgaa ggcggcatcg
     2701 agcgggattt ccttgcagca cacgcagcaa ctggtgctcg gttcattggc gttcatggtg
     2761 gtgttcctcc attggttgac gaagccgacg aaggccgccg ccggcatcgg cctggcgaac
     2821 aggaaaccct gcaccgtgtc gcaacccgcc tgccgcaacc acgcaaggca gtcgggtgtt
     2881 tccacaccct cggctaccac ctccattgtc gttttcagaa gacggctgca ctgaacgtca
     2941 gaagccgact gcactatagc agcggagggg ttggatccat caggcaacga cgggctgctg
     3001 ccggccatca gcggacgcag ggaggacttt ccgcaaccgg ccgttcgatg cggcaccgat
     3061 ggccttcgcg caggggtagt gaatccgcca ggattgactt gcgctgccct acctctcact
     3121 agtgaggggc ggcagcgcat caagcggtga gcgcactccg gcaccgccaa ctttcagcac
     3181 atgcgtgtaa atcatcgtcg tagagacgtc ggaatggccg agcagatcct gcacggttcg
     3241 aatgtcgtaa ccgctgcgga gcaaggccgt cgcgaacgag tggcggaggg tgtgcggtgt
     3301 ggcgggcttc gtgatgcctg cttgttctac ggcacgtttg aaggcgcgct gaaaggtctg
     3361 gtcatacatg tgatggcgac gcacgacacc gctccgtgga tcggtcgaat gcgtgtgctg
     3421 cgcaaaaacc cagaaccacg gccaggaatg cccggcgcgc ggatacttcc gctcaagggc
     3481 gtcgggaagc gcaacgccgc tgcggccctc ggcctggtcc ttcagccacc atgcccgtgc
     3541 acgcgacagc tgctcgcgca ggctgggtgc caagctctcg ggtaacatca aggcccgatc
     3601 cttggagccc ttgccctccc gcacgatgat cgtgccgtga tcgaaatcca gatccttgac
     3661 ccgcagttgc aaaccctcac tgatccgcat gcccgttcca tacagaagct gggcgaacaa
     3721 acgatgctcg ccttccagaa aaccgaggat gcgaaccact tcatccgggg tcagcaccac
     3781 cggcaagcgc cgcgacggcc gaggtcttcc gatctcctga agccagggca gatccgtgca
     3841 cagcaccttg ccgtagaaga acagcaaggc cgccaatgcc tgacgatgcg tggagaccga
     3901 aaccttgcgc tcgttcgcca gccaggacag aaatgcctcg acttcgctgc tgcccaaggt
     3961 tgccgggtga cgcacaccgt ggaaacggat gaaggcacga acccagtgga cataagcctg
     4021 ttcggttcgt aaactgtaat gcaagtagcg tatgcgctca cgcaactggt ccagaacctt
     4081 gaccgaacgc agcggtggta acggcgcagt ggcggttttc atggcttgtt atgactgttt
     4141 ttttgtacag tctatgcctc gggcatccaa gcagcaagcg cgttacgccg tgggtcgatg
     4201 tttgatgtta tggagcagca acgatgttac gcagcagggc agtcgcccta aaacaaagtt
     4261 agccattaag ggagttaaat tgaaaatatc attgatttct gcagtgtcag aaaatggcgt
     4321 aatcggtagt ggtcctgata tcccgtggtc agtaaaaggt gagcaactac tctttaaagc
     4381 gctcacatat aatcaatggc tccttgtcgg aagaaaaaca tttgactcta tgggtgttct
     4441 tccaaatcgc aaatatgcag tagtgtcaaa gaacggaatt tcaagctcaa atgaaaacgt
     4501 cctagttttt ccttcaatag aaaatgcttt gaaagagcta tcaaaagtta cagatcatgt
     4561 atatgtctct ggcgggggtc aaatctataa tagccttatt gaaaaagcag atataattca
     4621 tttgtctact gttcacgttg aagtcgaagg tgatatcaaa ttccctataa tgcctgagaa
     4681 tttcaatttg gttttgaaca gttttttatg tctaatataa attatacata ccagatttgg
     4741 aaaaaaggct aacaatgcgt tgcagcacca gtcgcttcgc tccttggaca gcttttaagt
     4801 cgcgtctttg tggttttgct gcgcaaaagt attccacaaa gccgcaactt aaaagctgcc
     4861 gctgaactta acgttaggca tcatgggtga atttttccct gcacaagttt tcaagcagct
     4921 gtcccacgct cgcgcggtga tcgagcgcca tctggctgcg acactggaca caatccacct
     4981 gttcggatct gcgatcgatg gagggctgaa gccggacagc gacatagact tgctcgtgac
     5041 cgtcagcgcc gcacctaacg attcgctccg gcaggcgcta atgctcgatt tgctgaaagt
     5101 ctcatcaccg ccaggcgatg gcggaacatg gcgaccgctg gagctaactg ttgtcgctcg
     5161 aagcgaagta gtgccttggc gctatccggc gcggcgtgag cttcagttcg gtgagtggct
     5221 ccgccacgac atcctttccg gaacgttcga gcctgccgtt ctggatcacg atcttgcgat
     5281 tttgctgacc aaggcgaggc aacacagcct tgcgcttcta ggcccatccg cagccacgtt
     5341 tttcgagccg gtgccgaagg agcatttctc caaggcgctt ttcgacacta ttgcccagtg
     5401 gaatgcagag tcggattgga agggtgacga gcggaacgtc gttcttgctc ttgctcgcat
     5461 ttggtacagc gcttcaactg gtctcattgc tcctaaggac gttgctgccg catgggtatc
     5521 ggagcgtttg cctgccgagc atcggcccct catctgcaag gcacgcgcgg cgtacctggg
     5581 tagcgaggac gacgacctag caatgcgcgt cgaagagacg gccgcgttcg ttcgatatgc
     5641 caaagcaacg attgagagaa tcttgcgttg agcggcatgt gcgaaaagtg catcgacccg
     5701 cgccgagggc atctgatgcc taactcggcg ttcaagcgga cgggctgcgc ccgccgctca
     5761 actatgcgtt agatgcacta agcacataat tgctcacagc caaactatca ggtcaagtct
     5821 gcttttatta tttttaagcg tgcataataa gccctacaca aattgggaga tatatcatga
     5881 aaggctggct ttttcttgtt atcgcaatag ttggcgaagt aatcgcaaca tccgcattaa
     5941 aatctagcga gggctttact aagcttgccc cttccgccgt tgtcataatc ggttatggca
     6001 tcgcatttta ttttctttct ctggttctga aatccatccc tgtcggtgtt gcttatgcag
     6061 tctggtcggg actcggcgtc gtcataatta cagccattgc ctggttgctt catgggcaaa
     6121 agcttgatgc gtggggcttt gtaggtatgg ggctcataat tgctgccttt ttgctcgccc
     6181 gatccccatc gtggaagtcg ctgcggaggc cgacgccatg gtgacggtgt tcggcattct
     6241 gaatctcacc gaggactcct tcttcgatga gagccggcgg ctagaccccg ccggcgctgt
     6301 caccgcggcg atcgaaatgc tgcgagtcgg atcagacgtc gtggatgtcg gaccggccgc
     6361 cagccatccg gacgcgaggc ctgtatcgcc ggccgatgag atcagacgta ttgcgccgct
     6421 cttagacgcc ctgtccgatc agatgcaccg tgtttcaatc gacagcttcc aaccggaaac
     6481 ccagcgctat gcgctcaagc gcggcgtggg ctacctgaac gatatccaag gatttcctga
     6541 ccctgcgctc tatcccgata ttgctgaggc ggactgcagg ctggtggtta tgcactcagc
     6601 gcagcgggat ggcatcgcca cccgcaccgg tcaccttcga cccgaagacg cgctcgacga
     6661 gattgtgcgg ttcttcgagg cgcgggtttc cgccttgcga cggagcgggg tcgctgccga
     6721 ccggctcatc ctcgatccgg ggatgggatt tttcttgagc cccgcaccgg aaacatcgct
     6781 gcacgtgctg tcgaaccttc aaaagctgaa gtcggcgttg gggcttccgc tattggtctc
     6841 ggtgtcgcgg aaatccttct tgggcgccac cgttggcctt cctgtaaagg atctgggtcc
     6901 agcgagcctt gcggcggaac ttcacgcgat cggcaatggc gctgactacg tccgcaccca
     6961 cgcgcctgga gatctgcgaa gcgcaatcac cttctcggaa accctcgcga aatttcgcag
     7021 tcgcgacgcc agagaccgag ggttagatca tgcctagcat tcaccttccg gccgcccgct
     7081 agcggaccct ggtcaggttc cgcgaaggtg ggcgcagaca tgctgggctc gtcaggatca
     7141 aactgcacta tgaggcggcg gttcataccg cgccagggga gcgaatggac agcgaggagc
     7201 ctccgaacgt tcgggtcgcc tgctcgggtg atatcgacga ggttgtgcgg ctgatgcacg
     7261 acgctgcggc gtggatgtcc gccaagggaa cgcccgcctg ggacgtcgcg cggatcgacc
     7321 ggacattcgc ggagaccttc gtcctgagat ccgagctcct agggatcgcc tcagaaaacg
     7381 gaaaataaag cacgctaagc cgtaagtaag cgtgctcctg tgaaagccac agctaaaact
     7441 gcgtagtaca catagaggta tttttttcta gatttatatc gaatttcgtt atcgaatttc
     7501 gcttattatt gatcaactcg ttgcagatca tgaaggcgaa agtatgacga ataaccctac
     7561 cgatgacagc agaccatggt cggtctttct tatttttctg cggcttggat tgacatcttt
     7621 tggcggcccc attgcgcact tgggctactt ccgcgccgaa tttgtcacac ggcggcgctg
     7681 gctctccgaa cggagctatg ctgacttggt cgcgctttgt cagttcttgc cagggcctgc
     7741 aagcagccag gtcggcatag cggtaggact gtctcgggct ggatacagcg gggcgctggc
     7801 tgcttgggct ggcttcacgc tgccgtctgc catagccttg atcctttttg cgctcggcat
     7861 ctccagctat ggcgattacg tctcgcaggg cgcgttgcat ggcttaaaag tggtggctgt
     7921 ggccgtggtc gctcaagcag tatggggcat ggcgcgtaac ctatgcacgg atgggctgcg
     7981 agtcaccatc atggcaattg ctacctgcgt cgttttactt gtgccgtccg cgtggggaca
     8041 ggttggcgtg attgctatcg caggcatcgc aggccggtta ttgttcaagc cagcgaaagt
     8101 tgttgagcat gaccccctac ctatcacggt cagtcaccgg gccggcgtgc tttggctctc
     8161 gctgttcttt gtcttgctga ttggcctgcc ggtgttggcc gaactgatgc caagtcaaac
     8221 catggcaatg gtggattcct tctatcgtgt cggatcactg gtgttcggcg gtggtcacgt
     8281 tgtgctgcca ttactgcaag ccgaagtggt gccctccggc tgggtcaaca atgaatcctt
     8341 tctcgcgggg tacggggcag ctcaagcggt gcccggccct ttgttcacgt tcgccgcgtt
     8401 tcttggtgcc tcgatgaaca ccgccccgtc gggctggatc ggcggcattg tgtgtctgct
     8461 ggctatcttc gcgccctcgt tcttgctggt cgtcggatca atgccatttt gggagcgttt
     8521 gcgccgcaat acaggcatcc aagctgcgct ggccgggatc aatgccgctg tagtcggctt
     8581 gctgctggcc gcgctgtatc agcctgtatg gactagcgcc atctttcagc cgcaagactt
     8641 cggcttggca ttagttgccc ttgtcgcact tatgttctgg aagctcccgc cgtggctggt
     8701 tgtcctcggt agcggtgcag ctgggtggct gttgagcgtc gctctgtgag gcacaaaaaa
     8761 tgactgacaa agacctctac ggcggtttga tccgcctgca catccttcac catgcagccg
     8821 aggaacctgt ctttgggctg gggatcatcg aagagctacg ccgacacggc tacgagatga
     8881 gcgctggcac cgtgtacccg atgctgcacg gcctggaaaa aaaaggctat ctgacctcac
     8941 gccacgaacg caccgggcga cgtgaacggc gtgtttatga catcactgaa caaggcagaa
     9001 ctgcacttgc tgatgcgaaa acaaaggtca aggagctgtt cggagagttg gtagaaggtg
     9061 gttgagtttt tgcttctatg tcaggttgag ctatacccta actggattgt cattttcaga
     9121 agacgactgc accagttgat tgggcgtaat ggctgttgtg cagccagctc ctgacagttc
     9181 aatatcagaa gtgatctgca ccaatctcga ctatgctcaa tactcgtgtg ggctctgttg
     9241 caaaaatcgt gaagcttgag catgcttggc ggagattgga cggacggaac gatgacggat
     9301 ttcaagtggc gccatttcca gggtgatgtg atcctgtggg cggtgcgctg gtattgtcgc
     9361 tatccgatca gctatcgcga ccttgaggaa atgctggcgg aacgcggcat ttcggtcgac
     9421 catacgacga tctatcgctg ggtccagtgc tacgccccgg agatggagaa gcggctgcgc
     9481 tggttctggc ggcgtggctt tgatccgagc tggcgcctgg atgaaaccta cgtcaaggtg
     9541 cggggcaagt ggacctacct gtaccgggca gtcgacaagc ggggcgacac gatcgatttc
     9601 tacctgtcgc cgacccgcag cgccaaggca gcgaagcggt tcctgggcaa ggccctgcga
     9661 ggcctgaagc actgggaaaa gcctgccacg ctcaataccg acaaagcgcc gagctatggt
     9721 gcagcgatca ccgaattgaa gcgcgaagga aagctggacc gggagacggc ccaccggcag
     9781 gtgaagtatc tcaataacgt gatcgaggcc gatcacggaa agctcaagat actgatcaag
     9841 ccggtgcgcg gtttcaaatc gatccccacg gcctatgcca cgatcaaggg attcgaagtc
     9901 atgcgagccc tgcgcaaagg acaggctcgc ccctggtgcc tgcagcccgg catcaggggc
     9961 gaggtgcgcc ttgtggagag agcttttggc attgggccct cggcgctgac ggaggccatg
    10021 ggcatgctca accaccattt cgcagcagcc gcctgatcgg cgcagagcga cagcctacct
    10081 ctgactgccg ccaatctttg caacagagcc cgccgtgcta gtctgctcgg tgatggtgga
    10141 gtgaagccaa cccgcaatcg ggttatgaat ctgcatcgcg attcgcaatc agctgtctct
    10201 tgagcatgtc gaactcctgc gatgttatct cgccgtgctc gtgctgctac accaacttgt
    10261 ccaactcatc cgccacaccg ctccccacca cctgcgatgg ccaggttgtt tgctgggcgc
    10321 attggcggag tatcgtctcg acccgggaca cccacaccgg cacaacctta cgggagtgat
    10381 tcactgtcaa agaatcggcc cggtgctctg acgcaagtat cgggatggtc accatttgta
    10441 agccgtagac ctgagtggtg atcaagactt cgataccacc gaccgtaccg gtactaatcg
    10501 acgacggtcg tgttcgtcgc ctgccgcagg gactctgcac acctccgttt acgcatgtgc
    10561 ctggaggagt tggaaatcgt cgtgttcggg aaacattaaa cacaggatgg cagcgatctg
    10621 agccagcaca tgatcagcta gctcaccatc cggatcgacg gcccactgca tcgtcgcgcc
    10681 agcgatgacc gagtgcagga gcaactcagc tgccgcagga gcacctgggg gcagtcgctt
    10741 gcggatcccc tccaccaccg cgcggttccg ctggatcgca agcgtgcgta gctccggcac
    10801 ctggagctcg taccaggaga tgagatagtt caccgagaag tcgttgcgag tgttcatgct
    10861 ccgaacgagc acctgcaaaa attcccagag cccttgcggc cctgcgccta tcggtatcgc
    10921 attcaggtaa tgccgcacct gctcgacgcc gcgctccatc atcctcacca gcagcgtatc
    10981 gcggttggtg aagcgctgga ttaacgctgc gcgggagagc cccacctcct ttgctactcc
    11041 gctgagcgtg aactctatgg gaccgcaacg cttcagcact acggtggcgg cctcgagtac
    11101 ctcgtcatcg gacttgagct tggggcgggg catcagtgtt caccttctgt atgggttggg
    11161 gcggaggctg tggctgccgc cgccattgta gcaaattgaa gacggagcga gagtagagcc
    11221 acgagccccg caaacacggc cgatacaacg aggccaggga gcggaccagc aaggtcgaca
    11281 aacgcgccgg ccgcaagcat aaccatgggc gaggctgaca gcatcaccgc cgagaccgtg
    11341 ccgagtaccc ggccgagaag ttctggcggc gtgcggttgt agatggcagc gttgagaatg
    11401 ggagagactg agccggtcag cagtcccacg agcgcgccca acaacatcag caccggcacg
    11461 cctggcaact gtgaaagcag aagcgagccc accgcagagc cacaaaatgc caccgccagc
    11521 cagttctgcg ctgatatccg ggcgccgacc gacgcatgaa tggcaatgcc aaggagacca
    11581 ccagccccca tcattgagga gaacagcccg agctctgcta cttggcgtcc tgcatctaca
    11641 aacagcgcag gcatgatgac gctgccgttg gcgccaacga tgcccacgaa gatcatcact
    11701 ataccaaaga gagggcgcag caggggttcg ctccagagaa aagcgacgcc ggcgcgcatg
    11761 gagagagtcg ccgtcgtggt catcgtccga gcggcacgcg cgggaagcac ccacgcgccg
    11821 agcagacctg caaggacgga gcagaacgcc gtcagcccga gcgttggcgc agcgccaagc
    11881 aggccgattg cggccccccc aagggccggg ccacctagaa tcgcgacgtt cccgatcacc
    11941 gctttcagtg acgagacgcg ctcaacggag agcccggcga cgtggccgag tttgggcagc
    12001 tcactgtcct gcgcggccat accgggtgcg tcgaacgcgg caccgagcac cacgcaagcg
    12061 atcagcccag tgttcgagag ggcgccaacg gcatcgagca gtgggatgct cgccatggcc
    12121 acgccgccca ccacacccga gatcaatgcg acgggcgcgc gcccgaaccg atcgacgagg
    12181 ccaccaccaa cccacgcgcc gatgatggtc gcgatgacgc tgctagcggc cgtggcgccc
    12241 gcccaggccg cgctctttgt atgagacagg acgaaccatg gaagcgcgag ggccgccacc
    12301 gcgttgccga tccggaagag aaaggtcgcc gcgaacagcg tcgcgagcgg gctatatcga
    12361 cgttcgctca ttccgctgcg gcgagctgcg ccttcgccgc agcgaggtac tcttcgttac
    12421 ccgagtcgag ggcgaagagt gcgtaggtga ccgccccgaa cgcaaggcgc tccgcgatgt
    12481 ggtgggcgag ccgcggccac acccggccac cggccgcttc atacgtgagg aggagcttcg
    12541 cgagcccctc ttcaccaaag accataaggt gcgcggccat gtcgatggca gggtcatcaa
    12601 cgcgggcctc gctccagtcg atcatcccgc tgacgcgctc cgtgttgtcg atgagcacat
    12661 ggcccacgta gagatcgcca tgcaccacca cggagaaatc tggccacgac gaatcgtcgt
    12721 cgagccagcg ctgccaccgg tggaggcgct tgtcgttcac cacgaactcg cgtcggacgc
    12781 ggtcaacgtc gtcggccacc ttctgacggg cctgcgtcgg tgtacggatg agcatccccg
    12841 catccacggc ggcggaaatg gggacggcat gcagggcggc gagcgcggtc gcgaagctct
    12901 ccgcgaagac ctccgagtcc tgcggcacga cccagtcggg cgtggacgaa ccaggctgga
    12961 tgaccatcgc agtcgagtct tcgagcatgg gataggcaac gagctcggcg ttggccacgc
    13021 gccagtccgg caccgcgaac ggcaggcgat tcttgagcat tgccagcacc cgcgcctctg
    13081 gttcgacctt cgcgcttacc tcggctcggc gcgggatgcg cagcacccac cgacgtccat
    13141 cgtcgacggt ggcgatcacg atcctatagt cgagcccaag ctcattgaca gtcagcgggc
    13201 catggagctt gagcccatgt cgggctgcaa gtgcgtacag ttgggaggta tcggcggtcg
    13261 tgactacggt catgattcac tcctgagggc ttgacgggtt tagccaccta aatgtaacag
    13321 tcacgtcggt tatattcaat ccggcactgt tgcaaagtta gcgatgaggc agccttttgt
    13381 cttattcaaa ggccttacat ttcaaaaact ctgcttacca ggcgcatttc gcccagggga
    13441 tcaccataat aaaatgctga ggcctggcct ttgcgtagtg cacgcatcac ctcaatacct
    13501 ttgatggtgg cgtaagccgt cttcatggat ttaaatccca gcgtggcgcc gattatccgt
    13561 ttcagtttgc catgatcgca ttcaatcacg ttgttccggt acttaatctg tcggtgttca
    13621 acgtcagacg ggcaccggcc ttcgcgtttg agcagagcaa gcgcgcgacc ataggcgggc
    13681 gctttatccg tgttgatgaa tcgcgggatc tgccacttct tcacgttgtt gaggatttta
    13741 cccagaaacc ggtatgcagc tttgctgtta cgacgggagg agagataaaa atcgacagtg
    13801 cggccccggc tgtcgacggc ccggtacaga tacgcccagc ggccattgac cttcacgtag
    13861 gtttcatcca tgtgccacgg gcaaagatcg gaagggttac gccagtacca gcgcagccgt
    13921 ttttccattt caggcgcata acgctgaacc cagcggtaaa tcgtggagtg atcgacattc
    13981 actccgcgtt cagccagcat ctcctgcagc tcacggtaac tgatgccgta tttgcagtac
    14041 cagcgtacgg cccacagaat gatgtcacgc tgaaatgccg gcctttgaat gggttcatgt
    14101 gcagctccat cagcaaaagg gatgataagt ttatcaccac cgactatttg caacagtgcc
    14161 ccatcaggga caaagatctg gctggtcgct ggcatcaccg atatgagaaa cggcttcaac
    14221 ggcctggcgg caaaggtgca gacgacgctg aaagacgatc cgatgtcagg tcacgttttt
    14281 atcttccgtg ggcgtaatgg cagtcaggta aagctcctct ggtctaccgg cgatggactg
    14341 tgtctgctga ccaaacggct ggagcgcggc cgcttcgcct ggccgtcagc ccgggatggc
    14401 aaagtgttcc tcacaccggc acagctggcg atgctccttg aagtatcgac tggcggcagc
    14461 ctaaaagact gcttacgtcc ctgactatgt tgtaagcctc tttatcctgg tcgacgctga
    14521 atgagcctgg taatataccc ggtatgagca gctcacttcc tgacgatatc aatgcactga
    14581 aacgtctcct tgccgaacag gaggcgctga accgtgccct gctggaaaag ctgaacgagc
    14641 gtgaacgcga aatagaccat ctgcaggcgc agctggataa actccgccgg atgaacttcg
    14701 gcagtcgttc cgaaaaagtc tcccgccgta tcgcacaaat ggaagccgat ctgaaccggc
    14761 ttcagaaaga gagcgataga gagcgatacg ctgactggta gggtgtatga cccggcagta
    14821 cagcgtccgt tgcgtcagac ccgcacccgt aagccgttcc ctgaatcact accccgtgac
    14881 gaaaagcggc tgttgcctgc ggcgccgtgc tgcccgaact gcggcggttc actgagctat
    14941 ctgggcgagg ataccgccga acagctggag ttgatgcgta gcgccttccg ggttatccgg
    15001 acggtacggg aaaaacatgc ctgtactcag tgcgatgcca tcgtgcaggc acctgcacct
    15061 tcgcggccca tcgagcgggg tatcgccgga ccggggctgc tggcccgcgt gctgacctcg
    15121 aagtatgcag agcacacccc gctgtatcgc cagtcagaaa tatacggccg gcaaggtgtg
    15181 gagctgagcc gttcactgct gtcgggctgg gtggatgcat gctgccggct gctgtctccg
    15241 ctggaagagg cgcttcatgg ctatgtgctg actgacggta agctccatgc tgatgacacg
    15301 cctgtcccgg tgctgttgcc aggcaataag aaaacgaaga ccgggcggtt aggacctacg
    15361 ttcgtgacga ccgtaacgcc gggtcaacgc tggcgccggc ggtgtggttc gcttacagcc
    15421 cggacagaaa aggcatccat ccgcagaccc atcttgcggg gttcagtggt gtactgcagg
    15481 cggatgctgt cacgaacggt gcaatagtga tccacaccca acgcctgaaa tcagatccag
    15541 ggggtaatct gctctcctga ttcaggagag tttatggtca cttttgagac agttatggaa
    15601 attaaaatcc tgcacaagca gggaatgagt agccggcgat tgccagagaa ctggggatct
    15661 cccgcaatac cgttaaacgt tatttgcagg caaaatctga gccgccaaaa tatacgccgc
    15721 gacctgctgt tgcttcactc ctggatgaat accgggatta tattcgtcaa cgcatcgccg
    15781 atgctcatcc ttacaaaatc ccggcaacgg taatcgctcg cgagatcaga gaccagggat
    15841 atcgtggcgg aatgaccatt ctcagggatt cattcgttct ctctcggttc ctcaggagca
    15901 ggagcctgcc gttcggttcg aaactgaacc cggacgacag atgcaggttg actggggcac
    15961 tatgcgtaat ggccgctcac cgcttcacgt gttcgttgct gttctcggat acagccgaat
    16021 gttgtacatc gaattcactg acaatatgcg ttatgacacg ctggagacct gccatcgtaa
    16081 tgcgttccgc ttctttggtg gtgtgccgcg cgaagtgttg tatgacaata tgaaaactgt
    16141 ggttctgcaa cgtgacgcat atcagaccgg tcagcaccgg ttccatcctt cgctgtggca
    16201 gttcggcaag gagatgggct tctctccccg actgtgtcgc cccttcaggg cacagactaa
    16261 aggtaaggtg gaacggatgg tgcagtacac ccgtaacagt ttttacattc cactaatgac
    16321 tcgcctgcgc ccgatgggga tcactgtcga tgttgaaaca gccaaccgcc acggtctgcg
    16381 ctggctgcac gatgtcgcta accaacgaaa gcatgaaaca atccaggccc gtcctgcgat
    16441 cgctggctcg aagagcagca gtccatgctg gcactgcctc cggagaaaaa agagtatgac
    16501 gtgcatcctg gtgaaaatct ggtgaacttc gacaaacacc ccctgcatca tccactctcc
    16561 atctacgact cattctgcag aggagtggcg tgatgatgga actgcaacat caacgactga
    16621 tggcgctcgc cgggcagttg caactggaaa gccttataag cgcagcgcct gcgctgtcac
    16681 aacaggcagt agaccaggaa tggagttata tggacttcct ggagcatctg cttcatgaag
    16741 aaaaactggc acgtcatcaa cgtaaacagg cgatgtatac ccgaatggca gccttcccgg
    16801 cggtgaaaac gttcgaagag tatgacttca cattcgccac cggagcaccg cagaagcaac
    16861 tccagtcgtt acgctcactc agcttcatag aacgtaatga aaatatcgta ttactggggc
    16921 catcaggtgt ggggaaaacc catctggcaa tagcgatggg ctatgaagca gtccgtgcag
    16981 gtatcaaagt tcgcttcaca acagcagcag atctgttact tcagttatct acggcacaac
    17041 gtcagggccg ttataaaacg acgcttcagc gtggagtaat ggccccccgc ctgctcatca
    17101 ttgatgaaat aggctatctg ccgttcagtc aggaagaagc aaagctgttc ttccaggtca
    17161 tcgctaaacg ttacgaaaag agcgcaatga tcctgacatc caatctgccg ttcgggcagt
    17221 gggatcaaac gttcgccggt gatgcagcac tgacctcagc gatgctggac cgtatcttac
    17281 accactcaca tgtcgttcaa atcaaaggag aaagctatcg actcagacag aaacgaaagg
    17341 ccggggttat agcagaagct aatcctgagt aaaacggtgg atcaatattg ggccgttggt
    17401 ggagatataa gtggatcact tttcatccgt cgttgacagg atgcatacgc cgggttcaac
    17461 gagctgtacc gggatggccg gataacggaa gccgcctgtt gggctcacgc ccgccgtaaa
    17521 atccacgatg tgcacgttcg caccccgtca gccctgacgg aggaagcgct gaaacggatc
    17581 ggcgaactgt acgccatcga ggcagagata aggggaatga cggcggagca acgccttgcc
    17641 gaacgtcagt tgaaaacgaa accgctgctg aaatccctgg aaagctggct gcgtgaaaag
    17701 atgaaaaccc tgtcgcgaca ctcagaactg gcgaaagcgt tcgcatacgc cctgaaccag
    17761 tggccggcgc tgacgtacta tgcagatgat ggctgggctg aggcggacaa taacatcgct
    17821 gaaaatgcgt tgcggatggt cagtctgggc cgcaaaaact acctgttctt cggttcggat
    17881 catggaggag agcgggagcg ctgctgtaca gcctgatcgg gacgtgcaaa ctgaacggag
    17941 tggagccaga aagctacctc cgctatgtcc ttgacgtcat agccgactgg ccgataaacc
    18001 gggtcggcga actgctcccc tggcgcgtag cactgccgac tgaataacac atccccgtca
    18061 atacggttct tgctgcacgc ttacaatttc agggcaggga atagtattgt taatttcggg
    18121 agaaacttaa agttgccaca tcgacagttt catcacacag gcttttgtcc tgaaaacttt
    18181 tcttattttg gactttcgcc agccactgtc caatatgaag agaaggtact gtgacgatac
    18241 catcctcatt agttacaaag gtgagttctg ctttatgaac aggatgtttg tgctcaactg
    18301 catgagtatg acgggatgat ttcagataac tgaccgagtc aagctccatg atagctccgg
    18361 cgagcgggga cgttttatac aggactttca gcttcacatc acactgaaac gacttatatc
    18421 ggataacgga atgatttcaa gctcatgccc gttggagact gatagagttg tgctggcatc
    18481 tgctgttcac caggaataaa agatttcgca tatttagtga caaactcaca gtaagccaca
    18541 tcatttctgc cctcccggct gaccggtttc catcctgaag aggttctcga ccagtatccc
    18601 ggtttcatat atgttgacaa aacgtagcca ttatctttgc ttgcagactc agttttatag
    18661 acataatccg tggacgctgg cttcagtgtt attgtctctt tcccgttata aatccgggat
    18721 tttcaaagaa attccttctg tcaggaattg tgccctttga ggggaaatta tgaccataac
    18781 caatctctgc ggtaatgttg ttctctgcct gtttacctgt aatccagaca tcgtgggcca
    18841 ggacatgccc cgatgctgtc agacaaagag ctaagatata acctgtattt ttcatcatga
    18901 tttgttacca ctgataacgg gtataaagac tgacagttct gcctgaaagc ggcactcctt
    18961 tgcattcatg gcaagcttgt tgaaggcatt atccagagcc actgatgcct caagccttta
    19021 acacttacag gcttataaga cagtgaaaag gaatgtacgg catagccagc ctgatgggga
    19081 tcgccttttt tcacatgcgt ggctgctgcc gaaagttcag cacgccatcc ggcagaaact
    19141 cctccatgac caacaggtat acttatgtca ctgatgagtg tgtcaggatt gccggagccc
    19201 agccattccc tgctgctggc atccatactt tccgtgcggt tataagaaag catccagtca
    19261 aaataatcag actggtaatt tccctgcata tcccatcccc agatacgggc ccggatacat
    19321 tataagaata agaaacgcat cgtttcatat ccacgcgcgt ggcaatatag tttctggcat
    19381 ccgttccgaa atatccgcct ttcaactgca gccgatcatt gcctgtaagc aggccgtcca
    19441 gttgaatacc tgcgccaatc tcacgggtaa tgttattttc tggtttcaga ttaaggttag
    19501 gtacccagta attggtttac ccttgcgtaa aatgtacatc atccctgtac atttctgcca
    19561 ttgtgggggc acggaatgca gaggatatgg agccgtacat catcagccat ctgtcggtga
    19621 gactgaatcg ccgcccttgt gggacaggcg ttcggctttc agttctccgg cacggggatt
    19681 gaagctcttg taccggtcat agcgggaacc ggacgatatg ttaccgggta gcttttcatt
    19741 gtcatttcat cctggaaata caacgatgta aagtcaatgt ttccttccgg atatagtgtg
    19801 gcagagcctt ctggcttctg ctgctgacgg taatattcag cgccatctta actgatgggc
    19861 tcccggaaaa atcagagtat gactcctgtt gaacaacatt aacaccggag gttctgttgt
    19921 ttctccattc tgccgttttg ttgtgaccgt ttgtcttgat agtgatatca ctgagatata
    19981 aagttgactt tacattgatg aggctgttat ccacagagcg tactggtacc agaactgtac
    20041 gtcattttgt actgtttttc tgtcacgcag gcgctgtcac catgtgtctg agtgggattg
    20101 cccggttcag tggtgttatt ccggtagaga acgcaagctg gcacctgctt tgttactgtc
    20161 tgttataccg aacagagcct ttcgcaaaca gggctgcagg tttttccttg ttaggtgcgc
    20221 gcgctcaacc atcactttga tagatattac ctcttttacg cataatgaca gaaaggacgc
    20281 atctgttttt ccggttttac cgaaccaggt gagccccgag cctgtgctgt ggtcaccact
    20341 ggcgatattt ccccacagac ttaaaccgtt tgtctctccg gggaggaaat ctgctgcatc
    20401 ggcagttctg aagtccacaa cacctcccag cccgccactg ccgtacagac tggagtttgg
    20461 tccgcggaca acttcgatac gtttgacgag tgccggatat ccagataagt gccactgctt
    20521 tttgccatgt cactgagttg acggatgccg tcaacaagaa caagtacccc gctttgtcat
    20581 aagccgcgta gattaaaggt ctgcccattg tccgtcctgc accagtctgg ctgagaccgg
    20641 caacaccttt cagcatgccg gctgatgtga ccgcattctg actccatggc gtgtcattcg
    20701 tgacgacact gaccattgac ggcgtttcaa ataccgtgtt ctgatttcct gtcgcgacaa
    20761 cgtgattgta tctttagcca tagaagaatg actggtctct gcctgtaacc ctatcgggag
    20821 tatgattaat gtacaaatga cgtttctgat tacgttcata tacatgcgaa aatattgtta
    20881 atattgatat gttataacat atcattttat taatgcaacc ctgatcacgc agcgttcagt
    20941 gataaccagt gaatagcgac tctaataccc ggtcgctctg caatgtatca gcgcctgcga
    21001 ccgatgctat ggatattgat ttttctacga taagagaacc agcaatacgg aatttagact
    21061 ggccccctga atctccagac aaccaatatc acttaaataa tgatagtctt aatactagtt
    21121 tttagactag tcattggaga acagatgatt gatgtcttag gaccggagaa acgcagacgg
    21181 cgtactacac aggaaaagat cgctattgtt cagcagagct ttgaaccggg aatgacggtc
    21241 tccctttttc ccggcaacac ggtgtggcag ccagccagtt atttctctgg cgcaaggcaa
    21301 atacaggagg gaagtctt
//
