LOCUS       CP088525               20186 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain E16EC0715 plasmid pE16EC0715-5, complete
            sequence.
ACCESSION   CP088525
VERSION     CP088525.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391650
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20186)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20186)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 129x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 11:54:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 4,881
            CDSs (total)                      :: 4,754
            Genes (coding)                    :: 4,472
            CDSs (with protein)               :: 4,472
            Genes (RNA)                       :: 127
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 17
            Pseudo Genes (total)              :: 282
            CDSs (without protein)            :: 282
            Pseudo Genes (ambiguous residues) :: 0 of 282
            Pseudo Genes (frameshifted)       :: 91 of 282
            Pseudo Genes (incomplete)         :: 195 of 282
            Pseudo Genes (internal stop)      :: 38 of 282
            Pseudo Genes (multiple problems)  :: 41 of 282
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20186
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="E16EC0715"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pE16EC0715-5"
                     /geo_loc_name="South Korea"
                     /lat_lon="34.87 N 126.99 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            1..114
                     /locus_tag="LQQ60_24305"
                     /pseudo=""
     CDS             1..114
                     /locus_tag="LQQ60_24305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004150760.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(696..1003)
                     /locus_tag="LQQ60_24310"
                     /pseudo=""
     CDS             complement(696..1003)
                     /locus_tag="LQQ60_24310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518821.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(1707..2163)
                     /locus_tag="LQQ60_24315"
                     /pseudo=""
     CDS             complement(1707..2163)
                     /locus_tag="LQQ60_24315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418053.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /name="sel1 repeat family protein"
     gene            complement(2368..2532)
                     /locus_tag="LQQ60_24320"
     CDS             complement(2368..2532)
                     /locus_tag="LQQ60_24320"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGF55899.1"
                     /translation="MTAKDLAYLIKFDGNYKDGMTVWLFSCNTGKGQNSFASQLAKELH
                     TNVIGPDTL"
                     /name="hypothetical protein"
     gene            complement(2661..3129)
                     /locus_tag="LQQ60_24325"
                     /pseudo=""
     CDS             complement(2661..3129)
                     /locus_tag="LQQ60_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014958.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RHS domain-containing protein"
                     /name="RHS domain-containing protein"
     gene            complement(3157..3826)
                     /locus_tag="LQQ60_24330"
                     /pseudo=""
     CDS             complement(3157..3826)
                     /locus_tag="LQQ60_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /name="HEAT repeat domain-containing protein"
     gene            3916..5139
                     /locus_tag="LQQ60_24335"
                     /pseudo=""
     CDS             3916..5139
                     /locus_tag="LQQ60_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            6359..7549
                     /locus_tag="LQQ60_24340"
                     /pseudo=""
     CDS             6359..7549
                     /locus_tag="LQQ60_24340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450492.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /name="GTP-binding protein"
     gene            7727..7876
                     /locus_tag="LQQ60_24345"
                     /pseudo=""
     CDS             7727..7876
                     /locus_tag="LQQ60_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611434.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            8185..9574
                     /locus_tag="LQQ60_24350"
                     /pseudo=""
     CDS             8185..9574
                     /locus_tag="LQQ60_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996655.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /name="ISNCY family transposase"
     gene            complement(9652..10349)
                     /locus_tag="LQQ60_24355"
     CDS             complement(join(9652..10100,10100..10349))
                     /locus_tag="LQQ60_24355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
                     /protein_id="UGF55900.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1A family transposase"
     gene            complement(10417..10707)
                     /locus_tag="LQQ60_24360"
                     /pseudo=""
     CDS             complement(10417..10707)
                     /locus_tag="LQQ60_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611465.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            10846..11025
                     /locus_tag="LQQ60_24365"
                     /pseudo=""
     CDS             10846..11025
                     /locus_tag="LQQ60_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611456.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            12322..13275
                     /locus_tag="LQQ60_24370"
     CDS             12322..13275
                     /locus_tag="LQQ60_24370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001201845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease"
                     /protein_id="UGF55896.1"
                     /translation="MYLKILATALSAPVAFAALASDTGLSFTPEKISTEIDFGTLSGKA
                     KERVYLPEEKGRKASQLDWKYSNAPIVKGAFNWDLLPRVSVGASGWTTLAGRGGNMVDR
                     DWLDTSNPGTWTDESKHPNTRLNFANEFDLNIKGWLLNQPDYQLGLMAGYQENRYSFTA
                     KGGSYIYSSEGGFRDETGSFPDGERAIGYKQHFKMPYIGLTGNYRYDSFEFGGSFKYSG
                     WVKASDNDEHYNPEKRITYRSDVNNQNYYSVSLHAGYYITPAAKVYVEGTWNRITNKKG
                     DTSLYSRNLNISDHTKNGAGIESYNFMTTAGLKYYF"
                     /name="omptin family outer membrane protease"
     gene            13708..14814
                     /locus_tag="LQQ60_24375"
                     /pseudo=""
     CDS             13708..14814
                     /locus_tag="LQQ60_24375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004149557.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /name="SDR family oxidoreductase"
     gene            14882..15783
                     /locus_tag="LQQ60_24380"
                     /pseudo=""
     CDS             14882..15783
                     /locus_tag="LQQ60_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="antimicrobial resistance protein Mig-14"
                     /name="antimicrobial resistance protein Mig-14"
     gene            16467..17207
                     /locus_tag="LQQ60_24385"
     CDS             16467..17207
                     /locus_tag="LQQ60_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="UGF55897.1"
                     /translation="MNSIIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAYL
                     LAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLDGVRPFVRILSEKVR
                     ARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAVRRA
                     EADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFALDMAA
                     TLAVPFTGDGRDAAEILRTLPPLR"
                     /name="site-specific integrase"
     gene            complement(17492..18467)
                     /locus_tag="LQQ60_24390"
                     /pseudo=""
     CDS             complement(17492..18467)
                     /locus_tag="LQQ60_24390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            19212..19529
                     /locus_tag="LQQ60_24395"
                     /pseudo=""
     CDS             19212..19529
                     /locus_tag="LQQ60_24395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /name="IS21 family transposase"
     gene            19533..19637
                     /locus_tag="LQQ60_24400"
                     /pseudo=""
     CDS             19533..19637
                     /locus_tag="LQQ60_24400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            19863..20057
                     /locus_tag="LQQ60_24405"
     CDS             19863..20057
                     /locus_tag="LQQ60_24405"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGF55898.1"
                     /translation="MEKLSLPTQEQPDIIAAACRALNHVWREGYRYMKAGVMLADFTPS
                     GIAQPGLFDEIQPRKNSES"
                     /name="hypothetical protein"
     Typing          complement(17493..18467)
                     /name="IncFIB"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.978"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggcatctacg cccaggtggc ggtttactcc gaccatttca gccatgtttc ggtgatgcgg
       61 aaagtgctgc taagaatgac cagctggatg cattatcttt atttggatca ttgaggggga
      121 gggggagatt atggaacttt gccctgtaag gactaattat ttttgcattt acttcattag
      181 ctgcgatgat ttttctttaa tattcattat gttaataagt tctggatgag tgtgctctca
      241 tgtggatttt ttatccgtct tgttctgccg caggatgaga ctatacatcg tcgagatcgc
      301 aatgatgata tgagttgttc ctcctgcgac ggctctaatc aaaaagagca ggagtgcttt
      361 tccaactatt gcgatgatgg ctttattatc tgaaggatga cagtcacatt taaaaaatat
      421 ttaatctata gatcacaatg tagggtcatg gaatatatgt atacaactat tttcttcttc
      481 acttttaatt atcgtattca tttaaaacta agttaaaaaa actcctggag agtgagttat
      541 taatatattt tttaaataaa attaagttat cattcatcga tgcactttat agaatcatca
      601 atggccataa tagtactatt aactctcaat ttatattttt atcatcacta caaatattaa
      661 ctgatttata tcaatgattt ttttattctt atcttttatt tatttactgt ttcaatgcaa
      721 tcagcggcaa gttggagtgg atttagattt ttcagatatg gtcttatgat ctttccctta
      781 cttaataaat agcatgtata ggattcgaaa gtccagcatc tatttgtacc tcattatatt
      841 agataaggat gtgagaaatt ccttgttatc attcgcagcc atatatgcca gtccgagttc
      901 agcctctgcg gccttacagg caaaatagct tagtgaacac gcttttcgtg ccctctttag
      961 tactggctga tattagtgcc aataatattg ctttgtctgc caaatctaac tctctctctg
     1021 aaattgtctt gcagtaactg cactcgcaga aatagagaaa aaaatacaat tgttaataac
     1081 cttgccatat tttttgtccg taactgttaa tgtgctatct ggctctgaaa atattaactc
     1141 atttaatttt tgcatgtcat tagataaacc agttatacaa cccctcggaa cagaatcgag
     1201 gtcctaaaga cggaccaaaa gcgtttaaac aactagtatt gaaaatccat tgcgattata
     1261 agttcctgta ttaactgacg gtactaatcg tatgccgtca ggttttctat tgcttgctcc
     1321 gggtcattaa cattccaact ccataggcct tgaggtattg gccatctatt tataaatgtg
     1381 tacaacgggg attattttta cattgcatat tattaccaga aacgactgga atactaagca
     1441 catcataaaa attatcatca catggtatat ctgaaacaca cgaaagcata cctaaagtta
     1501 tgctgtataa caggtggcta atcccaaggg gatcgttcca gaaatcgggt tcaacggata
     1561 ctgataaaaa ttccacctac cttccagccc aatcggagcc tgagtgttat accgccctgc
     1621 tgcggttaat gttaccgata atagttatag tacagccctg attcatcatc atactactgc
     1681 tgcggcagtc tgatgaacta ttgcttttac gatttctcct tattcttcct tctatccatt
     1741 cgctttagct ttttgagctc ttgaagtttg ctctttgcat caatattacc gttattacag
     1801 cgaattccat ccaataaaag ctctattcaa attataatat tctgataatg ttggatttgt
     1861 atctgataaa aagaccccat aataaactgc gctgtaacat tcccctgaga tgctgatctt
     1921 tccaagaatc gcaattgttt atcaatatta ttttagtaaa gcagtaatat tgatatagtc
     1981 gaaatgatgc ctctgaatca ccatgttgtg atttatactc agtttcaatc agcttttctt
     2041 cacttaaatc ataggtcatt gctgtagatt cccatcacac tttcgttttc tttattttca
     2101 catcagcacc atgcaattga ccaatagaga aaaataaaaa aatagtaaca agcatgcttt
     2161 catacatcta caacctatct tatatcactg gatttttctg gcgtaccttg catattagaa
     2221 atggggtgcc cagatggccc atatgttatc caattaccaa ggtcttttgt tgttatagcc
     2281 attagatcct tatttgaatt aaggttcgtt ggtgctgtta gcactgtatc catttttaac
     2341 ttaccattag ttcctcgccc caccacgtca tagcgtgtca ggtcctatta catttgtatg
     2401 taactcttta gctaattggc tagcaaatga attttgtcct ttacctgtat tacaagaaaa
     2461 taaccaaact gtcatcccat ctttataatt cccatcaaat ttaattagat atgctagatc
     2521 tttagctgtc atgatactgc gcgttgcgga ttcaatagat gtgggggtac catgcccccc
     2581 gattgtgaaa acgcctggga tattaatctc atcagctaca gaatggataa gatcactttc
     2641 ggggtataaa ttatatcaac caaaccttgc ggatctacat ttatgaccgg attcaatgga
     2701 tactgataaa aattccatcc ccccttcagc ccaatcggat cctgagtgat ataccgcccc
     2761 tgcagcgggt cataatagcg gtggcggttg taatacaggc cggactcctc atcatactgc
     2821 tgacccggca ggcgaatgag ctgctgcaga tgatgcggtt ctcatcactc agcaggttgc
     2881 cccattcatc atattctgcg caccacgctg ttgccccttc cgtgctgatg agcgccagcg
     2941 gcaggccgcg atggtcgcag tggtacaggt ggatttttcg cgccggcgtg taccacgggt
     3001 ccatctggtt tttcatctgc tccacggtca ggccgcacga tgccagccag cggcggcttt
     3061 cctcactcac ccggtcagcc aggatttcac tttccagccg gtcgagcatc tgcaccgtgc
     3121 cggcgggaat cccccactgt gcataggcaa ctcacgctat gaacgcttca gcttatcaat
     3181 agcggaagtt ataatttcat tgtcatcaaa cttgtacaac atagtatcta aaacaggaag
     3241 cagcgtttta tcacctaatt cacccgcagc ttcaatgatc atcataaaca gtattttttt
     3301 aactcatcgc ataaaacaga taaaaccctt ttatcttttc tgtaggaaag tccgattatt
     3361 gcttcaatac ggacttcctc atttttatcc tgaagcatct ccacaaaaac aatccctaat
     3421 atcactatta tcatattatt gatatttatt gcaaatgcgg cccagtttct gacatctcca
     3481 tttggatctt ttaacagatt aatcaatagt ggaattgttg ctttatcatt gataacagaa
     3541 atagcaaatg ctgtagcacg tctgacatta gtcgatttat caaaagcagt aatttgagat
     3601 tgttctacta ttttaggtga ataattgggt ttttcttgca tcgctgagcc gttgactcga
     3661 ttgccgtagc tcgaacgcaa gcgctcttat cattcaatgc catattgttc aaaatattaa
     3721 aaacattatc ttcgcatttt ttgcaaattt ttatttgccc gagtataaat gctccgatat
     3781 ctctacggat ataattttta tcagagcaga actcaattgc caatctagac tggcccctga
     3841 atctccagac aaccaatatc acttaaataa gtgatagtct taatactagt ttttagacta
     3901 gtcattggag aacagatgat tgatgtctta gggccggaga aacgcagacg gcgtaccaca
     3961 caggaaaaga tcgcaattgt tcagcagagc tttgaaccgg ggatgacggt ctccctcgtt
     4021 gcccggcaac atggtgtagc agccagccag ttatttctct ggcgtaagca ataccaggaa
     4081 ggaagtctta ctgctgtcgc cgccggagaa caggttgttc ctgcctctga acttgctgcc
     4141 gccatgaagc agattaaaga actccagcgc ctgctcggca agaaaacgat ggaaaatgaa
     4201 ctcctcaaag aagccgttga atatggacgg gcaaaaaagt ggatagcgca cgcgccctta
     4261 ttgcccgggg atggggagta agcttagtca gccgttgtct ccgggtgtcg cgtgcgcagt
     4321 tgcacgtcat tctcagacga accgatgact ggatggatgg ccgccgcagt cgtcacactg
     4381 atgatacggg tgcttctccg tatacaccat gttatcggag agctgcccac gtatggttat
     4441 cgtcgggtat gggcgctgct tcgcagacag gcagaacttg atggtatgcc tgcgatcaat
     4501 gccaaacgtg tttaccggat catgcgccag aatgcgctgt tgcttgagcg aaaactgctg
     4561 taccgccatc gaaacgggca catacaggca gagtggccgt gaaagaaagc aatcagcgat
     4621 ggtgctctga cgggttcgag ttctgctgtg ataacggaga gagactgcgt gtcacgttcg
     4681 cgctggactg ctgtgatcgt gaggcactgc actgggcggt cactacggcg gcttcaacag
     4741 tgaaacagta caggacgtca tgctgggagc ggtggaacgc cgcttcggca acgatcttcc
     4801 gtcgtctcca gtggagtggc tgacggataa tggttcatgc taccgggcta atgaaacacg
     4861 ccagttcgcc cggatgttgg gacttgaacc gaagaacacg gcgtgcggag tccggagagt
     4921 aacggaatag cagagagctt cgtgaaaacg ataaagcgtg actacatcag tatcatgccc
     4981 aaaccagacg ggttaacggc agcaaagaac cttgcagagg cgttcgagca ttataacgaa
     5041 tggcatccgc atagtgcgct gggttatcgc tcgccacggg aatatctgcg gcagcgggct
     5101 tgtaatgggt taagtgataa cagatgtctg gaaatatagg ggcaaatcca caatttctta
     5161 atataaaaga tccattacat tgctctgcaa ctataactgc gtattaccgt gaaggagaac
     5221 ggtgagtaac ggcgttttca aggccattgt caacgacgga tgaaaagtgg aatcctctgc
     5281 tgggattcag ctcctaatgc tacaaatctc attgatggct tgatgtaact tcacatatgg
     5341 tttcagcctc aaagaaatca ttttattaat tttaacgaag ggttggacaa aatgaggagg
     5401 tattagcttt gttttatgac gcatttccga aaatttccgt gccatatagt gagcatcttc
     5461 gcaagcttcc ataacaatag ttgtgtagga ggaattagta aggaattcga ataatttcga
     5521 gcacttggat tctgacagtt aaggactctg cctgttgcat cttggcagtg gacgttgaat
     5581 gaatttttgc ctagataaat accaatcaaa gatgacgtta ttcataatgg ttctccaaaa
     5641 aaacaccgtc agcgtactgc tgcagggtag ggtgatcatc taataaaatc cagtataact
     5701 ggataagaaa gatactcctg gtgaactggc tccgccacac ttaccaggaa acactattcc
     5761 ctggtcgaac ttatcctccg gaaacacctc ttttaagtgg tttgaagttt ttcggaatat
     5821 atcgcacaca gaaaaatgcg gatatcacag acagacttct gtcggttcca aatagtgcag
     5881 acccaaaagc tatgtatctt agtacagaac gggtgcccga catcctcgga acggatgtct
     5941 tttagatacg acaacagggt gaatagacag gaaaaataga atgatgcagc tctctttttt
     6001 acaaatgact gactctctga tatctagaac agataacgct cccggaatat acttatctag
     6061 gtgctatcac tgatacgaag agacatattc gaataaaaat acaacaacta gcaatctgta
     6121 attactttca ggaggtcaca cctcccactc ctgttcagaa caaatcttcc cccggagata
     6181 aaaatggtga taattatgct gatggagact aaataccaat aagtccggtg cgttctgtgg
     6241 caggttgaga cctcacagga aaaacgacaa caactcccgt cgacgttatg cgattcaatc
     6301 cggatgctct ttgtaccacc aagcgccttc ctcgctaact aactggtgta ctgctgatat
     6361 ggaaacaaca tctgtcatca ttctcaatgg cttcctcggc gcagggaaaa ccactctgct
     6421 gaaaaacctg ctcatacagg cacacgaaaa acagctttca gtctctgtca tagtcaatga
     6481 catgagcgaa ctggatgtgg acggcgtgct gatcgccaac acagatattg tagatgcaaa
     6541 agacaataat ttcgtaagta tcaccgcaga cagcatcagc agccccgcag gcctcaaaaa
     6601 gatggatctc gcaattaacc acctgcttga tcacaacaag ccggatgtga tgctgattga
     6661 aacctccgga agcagtcatc cgcttcctct ggtcaaatac ctgcgtcgcc attcacgtgt
     6721 acgcctgaag gcgtttttaa cactcgttga tactgtcatg ctccatgaag attacaatga
     6781 tgaaaaaaac tgatccccac tcttcaggaa aatctccggc ataacaaacg cggcctggag
     6841 aatttgctgg ccgagcaaat catgttctgc aacaggctgc tgctgaccag aaatgaccgc
     6901 ctgccctttg acattatctc cgctgtggca aaagccatac acccacttaa ccctccgtgg
     6961 atgtgctcgc ggtatcatgg ggaaatattg aactgagcac attactggcg atcccggact
     7021 acaattttga ccgtgttgag ttactcatca gtgaactgga agcacttgta ggaaacatgg
     7081 atactccgtg caacaatgag gaacttatat ggcgcgtcat cagggacgac aggccattcc
     7141 atccgcaaag attatgggat acctgtcacc gctttatggg catgggcgtt tatcgcagta
     7201 aaggtttttt tggctcccgg gagagatgat cttgccctgc tctggaatca gtcagcagga
     7261 agcatcagtc tggcgctcat tggctactgg aaagctggag tactggaaca tactgacaat
     7321 aatttaactc gtgaagaacg ttcagcgcta cagcgacaca tcgacacagc gctctgggcg
     7381 atttggcgat cgctgctgtc agttgactat cattggcaat gccactgaag ttaatgattt
     7441 tacacatgcc ttatcccttt gcttgttgac tgaagaagaa attcagtggt ggatgtcggg
     7501 tggagtattc cctgatccat ggccacagaa agttacccgc ctgtcctgac agaaattgca
     7561 ttcatatcag gcgtcctgtt gcatctggtg caggcagtgg ccccagaagg gctctccata
     7621 ccatctcgta tcatagccgg gggagagctg aaacacacgt cacgagaata gttgcattat
     7681 agtgggtatg cagagtagct acctgggagg tctttcgacc gctgactctg actaccgggt
     7741 taatgaaaca cgccagttcg ctcggatgtt gggacttaaa tcgaagaaca cggcggtgcg
     7801 gagtccggtg agtaatggaa tagcagagag cttcatgaaa acaataaaac gtgactacat
     7861 cagtatcatg cccaaacttg tggtctgttt ttatggagca gtttgtgctc agtactcaga
     7921 aaaaatattt tagagcctgt agagcagatg aatgcgtgga ttaggggagc gattaataag
     7981 aaaaagaagt ggaaatagaa gcagtaagct tcatgaagta agttaatatt caatgttatt
     8041 taacataaga tagattgtgc gcacaaacat tgtagaggct caatgctaat gtctatttgt
     8101 ggctcattag gaatgtccag gctatagttt ctcagatccc tatgtctaga caacgactca
     8161 ctttttcctg atgaggagtt ttctatggct ataaatgacg ccggaatgtt caccgtgaaa
     8221 gaaatcaatc gcctcaaaat ccttcaggat gtcatcgatc gcaatatccg tcctagacag
     8281 gctgccgaaa tgctgggcat cacgccacgt cattgcagcc gtctgctcaa acgttatcgc
     8341 cagtatgggc cgcttggcat gaacaaccag agtcgtggcc gcactggtaa ccgtctgttg
     8401 ccagcgtcac tgacagatca ggcactcagt ataatccggg agcactaccg tgattttggc
     8461 cccacgctag cgcgggaaaa gctggaggaa gttcacggtc tggtccttgg aaaggaaacc
     8521 atccgacgtc tcatgataaa ggccggactc tggattcccc gcagacaacg cgcaccgaaa
     8581 attcatcagc ctcgttaccg gcgtccttgt actggcgagc tgatacaaat tgatggctgc
     8641 gaccaccact ggtttgaaaa ccggggtcga ccctgttctg ccctggtcta tgttgacgat
     8701 gccaccagtc gcctgatgca cctgctgttt gtgaaatctg agtccacatt tacctatttt
     8761 gaagctacac gtggctatat cgagaaatac ggtaaaccga tgatcctcta cagcgataaa
     8821 gccagcgtat tcagagtcaa taataagcac gccaccaccg gccccggcga aacccagttt
     8881 gccagggcca tgcgctgcct taatattact cctttgtgtg ctgaaaccag ccaggcaaaa
     8941 ggccgcgttg aacgtgctca tttgacactt caggaccgac tcgttaagga gctcaggctt
     9001 aaggggatct gtacaataga agcggccaat gcatttgcag aaggattata accggcgctt
     9061 tgccaaagaa cccttgcatg attttaacgc gcaccggccg ctggcattag acgatgacct
     9121 tgatgcagaa tttacctagc gagagcctcg ccgggtatca aaaaatctga ctgtacaata
     9181 cgataaaatg ctctatctga ttgaggacaa cgagtacagt cgaagagcca tcggcaagta
     9241 tattgatgtc tggcattatc ctgacggaca taaggagctg cgactaaatg gcgtgctgct
     9301 gccctactcc acctatgacc ggctttctga ggttgatccc gtcgccattg tagataacaa
     9361 gagacttggc catgtgttgg atgttgcccg tcaggtccag agaaaacggg acaataatcg
     9421 ctcacaatcg ttaccttgtt ctggtgatga gccttcccgc agacggcacg cccctagcat
     9481 caacaaatct cagcgctcac tgaacgaaga tgacctactt gaagccatga taaagcttca
     9541 gggaagctct gaggccatct ttggtaaaag gtgaacttgg cggaaacctc gtactaactg
     9601 accaacggcg atgtgtgcgc tatctttcgg ctattgggta atgactccaa cttattgata
     9661 gtgttttatg ttcagataat gcccgatgac tttgtcatgc agctccaccg attttgaaaa
     9721 cgacagcgac ttccgtccca gccgtgccag gtgctgcctc agattcaggt tatgccgctc
     9781 aattcgctgc gtatatcgct tgctgattac gtgcagcttt cccttcaggc gggattcata
     9841 cagcggccag ccatccgtca tccatatcac cacgtcaaag ggtgacagca ggctcataag
     9901 acgccccagc gtcgccatag tgcgttcacc gaatacgtgc gcaacaaccg tcttccggag
     9961 cctgtcatac gcgtaaaaca gccagcgctg gcgcgattta gccccgacgt atccccactg
    10021 ttcgtccatt tccgcgcaga cgatgacgtc actgcccggc tgtatgcgcg aggttaccga
    10081 ctgcggcctg agttttttaa gtgacgtaaa atcgtgttga ggccaacgcc cataatgcgg
    10141 gcggttgccc ggcatccaac gccattcatg gccatatcaa tgattttctg gtgcgtaccg
    10201 ggttgagaag cggtgtaagt gaactgcagt tgccatgttt tacggcagtg agagcagaga
    10261 tagcgctgat gtccggcggt gcttttgccg ttacgcacca ctccgtcagt agctgaacag
    10321 gagggacagc tgatagaaac agaagccact ggagcacctc aaaaacacca tcatacacta
    10381 aatcagtaag ttggcagcat caccctccgc cttcgcaaaa taagcggaag cctggcgaag
    10441 gatatcgtta ctgcggcgca gttcacgatt ttcacgttcc agctctttca gacgctgacg
    10501 ttcagcggtg gtgagcccgc catcaccgcc tccggtatcc cgctcatgct ggcgtaccca
    10561 gacacgcaga gtctccggtg tacagccaat ctttggggca atggaacaaa ttgccgccca
    10621 ctgtgagtca tattcgccct gactttccag aaccatacga atcgccctct gacggacttc
    10681 gggggaaaaa cgagtatttt tagtcatcct gtttacctct ttctcaggga gtttagtctc
    10741 caggattccc ggggcggttc aaggattgcg gaaaaccatg tctatccagc tatgattcgc
    10801 atagattatg gccaggattt tttttatcca acacggacgt aatgcgcaga aaaacatgta
    10861 gtaaaactgg agattaccca atcaggtaag ttggcgcaga acgcttttat cgagagtttt
    10921 aaccggacat accgaacaaa aatactcggt ttttgtctgt tcagaacgct ggatgaaaag
    10981 cgggaactgg cggcaaactg gttgtcagaa tataacagtg aacgccatat caactactta
    11041 accatatgac actggaagaa catcactaac gccattattt ggtcacgatc tcaaaaggtg
    11101 catggaacta aaacgagtct gtttacaacg caagatgggt tatgttataa agtaacataa
    11161 atgagttggt aagcataaag taaagaggat aacttatagt gctcccctta tttaaagcat
    11221 tttgtttttt ttgtattcta ttgttaggct cagtattaat tcggggtaat aataatctta
    11281 tttcaccagt ggttagacaa gaattttttt tatcgaaaaa aacaacccca tccttttatc
    11341 agaaaattga tgcgtgcttt agcaacgtta atcttgactt tacatacaag tctgttgatt
    11401 actcagcatc taccattttg caatacatta gaagattaat aagaaagctt tacattaaat
    11461 aaaagagatg caattatcaa taaaataaga atatctcgtt aagaaatata gcaatatata
    11521 tgatatttca ggaaataagt aatcatacat ctattgattt ataaagtatt attggaagga
    11581 agtgttacat gaacgattta cgcactcccc tccattacac taataaacac caccgacttg
    11641 gtatttataa attttctaat aaaagcatca ttttcactga aacaaaataa atatcaatca
    11701 ctaagataat taacttatct gaacaagtaa tcacactcat atgttattag ttttcttatt
    11761 aatcagaaag gagggattta taaaccagca actttttttg taggtggagc cacggttgat
    11821 ttctgatatc aaccacctga gtttattttc gtcgaatggt aatgtcttgt cgcacaaacg
    11881 ctatctgaat aattaactgt aatggcgtta ttggtatatt tgccgacatt aacgctaata
    11941 aagaccctga ttgcttcata atcgcaggat ttggccattt tgtctccctt tagataagag
    12001 ttaacaaaat aaccccagga agaaggtacc ggtttccacg ttacagacgt tcccggcata
    12061 aagtgtccga ccagggcctt attcgcagtt accagcgccc tgtatgccct gatattttct
    12121 ggaacatgga tgaccggggc agtaatcata ccgggtttga ctgactcccc tgatattctg
    12181 acataaaagg gaataaataa agcgacatgt ggccacattg taaacaaacg ttaaacaaaa
    12241 cagcattttt cagttgacta ctacgagtaa ataaaaaaat atttatcaaa aacaaacgag
    12301 tggaatggag ttaacttgtc tatgtactta aagattcttg ctactgcact ctcagctcct
    12361 gtagcgtttg ctgcactggc ttctgatact gggctttctt ttacaccgga gaaaatcagt
    12421 acggagattg attttggcac tttaagtggc aaggccaaag aacgggttta tctgcctgaa
    12481 gaaaaagggc gcaaagccag ccagctggac tggaaataca gtaatgcgcc aattgtcaag
    12541 ggggcattta actgggatct gttacccaga gtatctgtcg gtgcctcagg gtggacaaca
    12601 ttagctggtc gtggaggcaa tatggtggac agggactggc tggatacgag caatcccgga
    12661 acctggactg atgagagtaa acatccgaat acccgtctaa attttgctaa tgaattcgac
    12721 ctgaatatta agggatggct cctgaatcaa ccagactatc agttaggtct tatggctggt
    12781 taccaggaaa atcgttatag ctttacagca aaaggaggct cttatatcta tagtagtgag
    12841 ggaggcttcc gggatgaaac gggatcattt ccagatggtg aaagagctat aggctacaaa
    12901 caacacttta aaatgcccta tatagggtta accggtaatt atcggtatga tagctttgag
    12961 ttcgggggga gtttcaaata tagcggatgg gtgaaggcat cggataatga tgagcattac
    13021 aaccctgaga aaaggatcac ctatcgtagc gatgtaaata atcagaacta ttactctgtc
    13081 tcactacatg ctggttatta tattacacct gcagctaaag tttatgtcga aggaacatgg
    13141 aaccgtatta ctaataagaa aggtgatact tctctgtact ccagaaattt gaatatatct
    13201 gatcacacca aaaatggtgc aggcattgaa agctataact ttatgaccac agctggtctg
    13261 aagtattatt tttaacctga agcatgcctg tttttaactt tttcatgaca ctttaaatat
    13321 gataaacaaa aggccagcac ttctgatggt ggtcttttga ttttttataa tatgtggagg
    13381 gtatatgtgc tcaacgataa aagtgtttct gttaactctt gtatttttaa agatgctgcc
    13441 ctgccactct tcatgcataa cgacacagtg ttatcgacat aaaaataatt gataagcgat
    13501 gttaacaata tgaactttat tataattcta ttactcgtca ataataagaa gaccatccaa
    13561 taaaaacaca cgcaataacc tgaaggattc tgccgtataa aaataaacat tgtttttaca
    13621 tttaatctct cttgattttg tttaatcatt gtttatgtaa gataatttat ttttataatg
    13681 atcacatgaa aacaaaagag gttagatatg aaattattat tacttacagg tgcaacagga
    13741 tttcttggtg gcgcggtcct ggataagctg ctggataact gtaataatat aaatttgcta
    13801 cttttagtac gagcacctac tccacaagcg ggactggaaa gaattaaaga aaatatgcgt
    13861 aaatttaatg tttgtgagga aaggttgcat gcattaacta atgataacat cttgcctggg
    13921 gatctaaata atccggaagc ctttctcatg gatcctcgtc ttgatgaagt cactcatgtt
    13981 ataaactgtg cggctatagc ttcttttggt aataatcctt ttatatggaa tgtgaatgtt
    14041 acaggtacac ttgcttttgc aagaagaatg gcaaaagtgg caggactgaa acgcttcctt
    14101 catgttggta ctgctatgtc ttgtacacct catacggggt cgctagttaa ggaagagtct
    14161 gcttcatcag aaacaggtga acatttagtg gagtatacgc attcaaaagc aacaatagaa
    14221 tatctgatgc gtaagcagtg tcctgattta cctttgttgg ttgcccgacc atcaattatt
    14281 gttggccaca gtcgtttagg gtgcttacct tcaaccagta ttttctgggt attcagaatg
    14341 ggttaatgtt gcaaaaattt atgtgctctc tggatgataa aatagatgtt atccctgtag
    14401 attattgtgc tgatgcattg ctaatgttgc ttgaaagctc gttaattaat ggtgagattg
    14461 ttcatatatc agcaggtaaa gaaagtagtg tgacgttctc tgctattgac gaagctgtag
    14521 cccgtgcttt gaactgtgat cctgttggag acagatatac taaagtcagt tatgacatac
    14581 tggcaatgag ccgtcatgat tttaaaatat tttggtccct gtaacgaacg ccttatgtta
    14641 aaagccattc gtttatatgg agcgttcagt atgctcaatg tttgtttcag taacgacaag
    14701 ctactgagta tcggaatgcc taaaccgcca aagtttactg attatattaa atactgtata
    14761 gaaacgacaa aacacctttc aattcaacaa caaatggaag ttgattttaa ataatattta
    14821 tcataatcag aattattgtt ggtgttgcac tcataatata aaaaacgccg aggatatgac
    14881 tttgtcaatt aaaaatataa agcgcattat tacggcctgg aaaccatcta cattcgaaac
    14941 gtacaaaaaa acttttgaaa aatacggtgg tagtgtaaac atgcatccgg atgttgtttc
    15001 atactttatg atacatcatg actggaagtt tgattttttt cactatgaaa aagatggtga
    15061 tatcaaaggc tcatattttc tgtgcaatgg aaaacaaatt gggataatgg caagaaggtc
    15121 ttatcctctt tcatctgatg aggtattaat tcctttttcc ccacatgcaa gatgtttttt
    15181 ccggataaaa ctaataaatt atcaattata aataaacaaa atattatcaa tgcaacatgg
    15241 aaaatagcca gaaaaaaaca aaattgtatt ataaaggaat ctttttcacc taaatttgaa
    15301 aaaactcgcc gaaatgaaat ccagagattt atcaggaatg gcggagagat taagtgtata
    15361 agccagttat ccgataaaga aatatccagc tcttatatat cactttttca ttcccggttt
    15421 ggaggtaccc taccttgcta cgaatatgat aatctgttaa tgtttatttc tcacttacga
    15481 gaacttatgt ttggccatgt gctattctgg gataataaac cgtgtgctat tgatatagta
    15541 ctgaaatctg aaagctcatg taatgtttat tatgacgttc caaatggtgc agttctgaat
    15601 gatgagaatt gcatgaaact aagtccggga agtgtcctta tgtggctgaa tatagataaa
    15661 gcacgaaggt attgtcagga taataataaa aagatgatat attctatcgg tgcattcaga
    15721 cctgaatgga aatataaact actatggtct gttccctgta aggttggtaa atgcttatgt
    15781 tagaatatgt ataaaggtaa gtaactatat aagagcgtcc agtctgcaaa tactcctcta
    15841 aacatggagg agtagattta taatatcata acatttacta aatcgtttta cattaatttc
    15901 aaatttgaaa ttaatgtatt ttgataacta tatatttttg attccgaaaa cagacatttc
    15961 tttctttgag tcagggctta cactcaaaat attaatattg tttgtgtgaa gacatattat
    16021 tcaataacga tggtgagaaa tatctgtaac tttttcgcat aatctaacca tttacttaat
    16081 tgttcattct gtgaacagaa tctgtttgtt atgtatcagg ttgatgatgt gattaagcag
    16141 tctgaaacca gaggaatatg gagtcagaaa ttttcagttg tcttttaagg gcgtctgcag
    16201 gattttttct ccgtttctgc ctgtcctggc attaccccaa ttctcccaaa aaccgtaaaa
    16261 cagccatcaa cccgcgtcat tactggcttc atggaggatc tgagcagaaa aacgatcctt
    16321 tacgcatttg gttttacccg caataatgcg ggataagaca acaaaaggat ccgcgcgctg
    16381 cgatttattg tcatggcagg atcggcccgt caggtgcaaa atacctgtat ccataaacag
    16441 tgcgtgcgct acgtgaaaaa taactcatga acagcatcat tcccttgcag aattcaccag
    16501 aacgcgtctc tctgctgccg atcgccccgg gggtggattt tgcaacagcg ctctccctga
    16561 gaagaatggc cacttccacg ggggccacac cggcctacct gctggccccg gaagtgagtg
    16621 cccttctttt ctatatgccg gatcagcgtc accatatgct gttcgccacc ctctggaata
    16681 ccggaatgcg tattggcgaa gcccggatgc tgacaccgga atcatttgac ctggatggag
    16741 taagaccgtt tgtgcggatc ctgtccgaaa aagtgcgtgc gcgacgcgga cgcccgccaa
    16801 aagatgaagt gcgcctggtt ccgctgacag atataagcta tgtcaggcag atggaaagct
    16861 ggatgatcac cacccggccc cgtcgtcgtg aaccattatg ggccgtgacc gacgaaacca
    16921 tgcgcaactg gctgaagcag gctgtcagac gggccgaagc tgacggggtg catttttcga
    16981 ttccggtaac gccgcatact ttccggcaca gctatatcat gcacatgctt tatcaccggc
    17041 agcccaggaa ggtcatccag gcactggctg gtcacaggga tccacgttcg atggaggttt
    17101 ataccagagt gtttgcactg gatatggctg ccacgctggc agtgcctttc acaggtgacg
    17161 ggcgggatgc tgcggagatc ctgcgtacac tgcctcccct gaggtgacgg catacgcgct
    17221 tccttatata agctgtggtc agcagaacag acataacata agctggagca tgtatataag
    17281 ctgtagtgag taagtcatgt tttatgaagg gagcaatgcc tcagcagcag gttacgggat
    17341 cacttacgta agggacaggc agatggcagc tcagctacag acagcactgc aggaaacaga
    17401 atataaactg cagtgagcag accactcact gcaccggtta atataagctg tagtcagtaa
    17461 aggagcgctc ttcactgact acagtttatg ttcagcggga tttgaagagt ttttccaggt
    17521 catccagcgt gatgcccagt ttctcaagca gggcaagctt ctccgccatc tccggactga
    17581 ctttttccgc aggtgaaggt tgcaacggat tttccttact ctcatcattc ggcgctttta
    17641 accggggcgc cggtagtgaa tacagaagaa ttttgtccgc ccccgctgga tctccgtgta
    17701 atcaagatat ccaatctcgc gcaactgctc cattgcccgt ctgaccgtct ggttctggga
    17761 aaatacagga gacttcagat tgaggcgtgc acgcagccgc gccagcgata tcggtgccgg
    17821 atcccggggc aggctctcta taaaggtgta gagtgcctgg gcggactccc gtcgcttcag
    17881 ggcattaatc gccttaagct ggagaaggac ttttctgtca aactggtaca gttcaaacag
    17941 gcggggatcg gcctgtaact gaacaatatc ccgctcagta tcgtagtagg ctgactgtac
    18001 cagatgggtg atgtattccc gggtgtgctt ctcatcggta cgggaaaacg agatcacggt
    18061 accggcaatg cgcttcaggg aagggctgat gcgctcacgc agcctcggga tgactggctt
    18121 gaaggtatac cacacagttt tgcaaactca acaaaaggca gttcaacttt gtcaccaatc
    18181 acgttatggc gggcaaagga atgaatgatc cccacccagg tcttgaaatc gttatccata
    18241 tccaggcggg ggccggtgat ctcaacctta tcgaatccct cagcacgggc cagggaaaga
    18301 cgtgtcagct cttccgtggc atcagtacgt gacagtgtat tttttttact gttcttcagt
    18361 gatttaaggg tcggtacaaa aacgcccaga cgcatcagcg ccacaggttg tacggtgttg
    18421 ttattgtttg gtgtcagtgt caccagttca ccggacgact tatccacctc gccgaacagt
    18481 tttttgatgt ctgaattttc gttttccaga aagcctccag cctgtggaca gtaaaagaat
    18541 aaacagaaaa tcgtgtgtca gaactccgct aactgactga agaaaaacct gcagcctgta
    18601 tttaacaact gagtctggca tactgaccat agtttatgtc attaacttac ttcagtatat
    18661 ggattactga atacagctta tcattagcat gttacagttt atcagtaaca tgccacagct
    18721 tatgtgatcg tggtcccggc ccatgagtga caaggtttgc agcgatatgg ggatctttaa
    18781 tggatccttt gttgatcatt catggatctg tttactggat cgggcctccg gatatgtgga
    18841 taaatcattc cagaaggaca gcgcacacaa ccgttttatg aaagggcttc agggcgtacc
    18901 tgctccctgt aactacagat acattgcgct tcctcgccgg ttcgcgggct tcgcccggtc
    18961 accggtctgc ggcgagcact gttttttctg atgtctgtct ttacaggtaa tttttgacgg
    19021 aatctgccgt acttcctgag cgtacggtca tatccgaagt acacttcata tgtgtgtttc
    19081 aatgccaggg attgtgtata caaactacag gtgtcagcgc cagtgatata agacggtaat
    19141 tcaccatttg gattgtccgc tccacccaca tgttgtttcc ttaaggttct cacaccagaa
    19201 aggacatcaa catgctgagc agagaggact tttacatgat aaagcaaatg cgccagcagg
    19261 cgcgtacatt gtcgatattg cggctcagat tggttgctct gaacggacgg tcagacgcta
    19321 cctcaaatac cctgaaccgc agccagaaag acccgccaca aaatggttaa gctgaaaccg
    19381 tttatggatt acatcgacat gcgcctggca gagaatgtct ggaatagcga ggttatcttc
    19441 gcggagatta aggcaatggg ttatacgggc ggacgttcca tgctgcgtta ctactccagc
    19501 ccaaacgtaa aatgcgtccg tcaaaaaaac aaggagagag ttaccggtta aaagagaaaa
    19561 cgtaaagctg gagtgctgac caaaaacaca cgccaatcag tgatgatgaa atggtgcaaa
    19621 gcggacagca tcagtaacga aagtatttag cgggcatgaa aatggcaaat aacggtcaaa
    19681 catcgtggcg ttgacatagt cgcagttttg gtgaacgaat cacagacaaa gatgccatgc
    19741 accaggctgt tgttcagtat gcagagcggc cgcagagaaa ctacgtgggg agcgtcagta
    19801 ttgccggcag gtgacgacat ttgtacggac atccccctga accctgttac agcaatgccg
    19861 ctgtggaaaa gctttcattg cccacacagg agcagccgga cattattgcc gccgcatgca
    19921 gagccttaaa ccatgtctgg cgtgaagggt accgctatat gaaggcagga gtcatgctgg
    19981 ctgatttcac accatcgggt atagcgcagc cgggattatt tgatgaaatc cagccccgta
    20041 aaaacagtga aagttaatga aacactcgat gaatgaacca gtcgggaaaa gggaaagtgt
    20101 ggttttgcgg ggcgaggaac cgcccctgaa tggcaaatga aacgggaatg ttgagtcagt
    20161 gttatacaac taaatggcga gatatt
//
