LOCUS       CP088359                6647 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain F17EC0098 plasmid pF17EC0098-3, complete
            sequence.
ACCESSION   CP088359
VERSION     CP088359.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391703
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6647)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6647)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 133x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 11:35:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,511
            CDSs (total)                      :: 5,393
            Genes (coding)                    :: 5,095
            CDSs (with protein)               :: 5,095
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 298
            CDSs (without protein)            :: 298
            Pseudo Genes (ambiguous residues) :: 0 of 298
            Pseudo Genes (frameshifted)       :: 130 of 298
            Pseudo Genes (incomplete)         :: 213 of 298
            Pseudo Genes (internal stop)      :: 55 of 298
            Pseudo Genes (multiple problems)  :: 85 of 298
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6647
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="F17EC0098"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pF17EC0098-3"
                     /geo_loc_name="South Korea"
                     /lat_lon="35.18 N 129.08 E"
                     /collection_date="2017"
                     /collected_by="Kor-GLASS"
     gene            complement(66..503)
                     /locus_tag="LQQ82_27445"
     CDS             complement(66..503)
                     /locus_tag="LQQ82_27445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="UGD37935.1"
                     /translation="MGHCHFMAWHTLRDALKMTGRSRSQFYRDMRAGLVSYRTGRDGRR
                     EFETSELIRAYGELKQNETPERHSEGHAENPHDQQTERILRELNELKQCLTLMLEDKQA
                     QDMDRRRQEAEREQLQNEIAQLRQALELEKKRGFWSRLFGR"
                     /name="entry exclusion protein 1"
     gene            763..2331
                     /gene="cea"
                     /locus_tag="LQQ82_27450"
     CDS             763..2331
                     /gene="cea"
                     /locus_tag="LQQ82_27450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin E1"
                     /protein_id="UGD37936.1"
                     /translation="METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKS
                     ESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRH
                     NASRTPSATELAHANNAAMQAEAERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIERE
                     KAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSS
                     IHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAG
                     KIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNL
                     LNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDV
                     LNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTG
                     DWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTIN
                     EVLGI"
                     /name="cea"
     gene            complement(2328..2555)
                     /locus_tag="LQQ82_27455"
     CDS             complement(2328..2555)
                     /locus_tag="LQQ82_27455"
                     /inference="COORDINATES: protein motif:HMM:NF015489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E1 immunity protein"
                     /protein_id="UGD37938.1"
                     /translation="MLYAIVISTILCPYSKYAIEHIAFNFIKKDFFERRKNLNNAPVAK
                     LNLFMLYNLLCLVLAIPFGLLGLFISIKNN"
                     /name="colicin E1 immunity protein"
     gene            2717..2854
                     /locus_tag="LQQ82_27460"
     CDS             2717..2854
                     /locus_tag="LQQ82_27460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="UGD37937.1"
                     /translation="MRKRFFVGIFAINLLVGCQANYIRDVQGGTIAPSSSSKLTGIAVQ
                     "
                     /name="colicin release lysis protein"
     gene            complement(3881..4072)
                     /locus_tag="LQQ82_27465"
     CDS             complement(3881..4072)
                     /locus_tag="LQQ82_27465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UGD37930.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDHA
                     DELYRSCLARFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            4136..4459
                     /locus_tag="LQQ82_27470"
     CDS             4136..4459
                     /locus_tag="LQQ82_27470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="UGD37931.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGKLPTL
                     APPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQGAR
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            4668..5099
                     /locus_tag="LQQ82_27475"
                     /pseudo=""
     CDS             4668..5099
                     /locus_tag="LQQ82_27475"
                     /inference="COORDINATES: protein motif:HMM:NF015397.2"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            5137..5655
                     /locus_tag="LQQ82_27480"
     CDS             5137..5655
                     /locus_tag="LQQ82_27480"
                     /inference="COORDINATES: protein motif:HMM:NF016710.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein MbeB"
                     /protein_id="UGD37932.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNNEFRRLGESVSEAVTSNE
                     TKIRDAIALFTASTEESLEKHREGVKEAMMQHRRDVLKLAGNTGMMLLGIVFLLFTASG
                     GTLWYLGGRIQANLEEIRKQEETLQKLNAKTWGVEFVQDGNRKFLVLPYGKSAEVIPFQ
                     GKEWVHLKE"
                     /name="mobilization protein MbeB"
     gene            5662..5895
                     /locus_tag="LQQ82_27485"
     CDS             5662..5895
                     /locus_tag="LQQ82_27485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="UGD37933.1"
                     /translation="MTELETHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDNA
                     MLNERVMQLSQQVQHLSEQTERLSQLYSENWR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(6213..6632)
                     /locus_tag="LQQ82_27490"
     CDS             complement(6213..6632)
                     /locus_tag="LQQ82_27490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="UGD37934.1"
                     /translation="MRRTGNKLCLIAMITATVALTACTPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLRGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     Typing          3709..3793
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="3.03e-37"
     Typing          complement(3140..3695)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.878"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          4450..5999
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttaaagtatt tattctcggt gagttattat ccgaagacta ttttatcatc agtctctgac
       61 agcgttcagc gaccgaacaa cctggaccag aatccccgtt tcttttccag ttccagtgcc
      121 tgcctgagct gggctatctc attttgtagc tgttcccgtt ctgcttcctg gcgtctgcga
      181 tccatatcct gtgcctgttt atcctcaagc atcagcgtca ggcattgttt cagctcattc
      241 agctcccgga gaatgcgttc tgtctgctga tcatgtggat tttctgcatg tccctcactg
      301 tgcctttctg gtgtctcatt ctgctttaat tcgccgtatg cccggatcag ttcactggtt
      361 tcaaactccc gtcgtccgtc cctgccggta cggtaactga caaggcctgc gcgcatatca
      421 cggtaaaact gtgaacgcga tctgcctgtc atttttagtg cgtcccggag tgtgtgccat
      481 gccataaagt gacagtgtcc catagatgtc tcatctcata gtttcagtaa aacataatga
      541 ggtctgagaa cggtaatgtt tgtgctggtt tttgtggcat cgggcgagaa tagcgcgtgg
      601 tgtgaaagac tgtttttttg atcgttttca caaaaatgga agtccacagt cttgacaggg
      661 aaaatgcagc ggcgtagctt ttatgctgta tataaaacca gtggttatat gtacagtatt
      721 tatttttaac ttattgtttt aaaagtcaaa gaggatttta taatggaaac cgcggtagcg
      781 tactataaag atggtgttcc ttatgatgat aagggacagg taattattac tcttttgaat
      841 ggtactcctg acgggagtgg ctctggcggc ggaggtggaa aaggaggcag taaaagtgaa
      901 agttctgcag ctattcatgc aactgctaaa tggtctactg ctcaattaaa gaaaacacag
      961 gcagagcagg ctgcccgggc aaaagctgca gcggaagcac aggcgaaagc aaaggcaaac
     1021 agggatgcgc tgactcagcg cctgaaggat atcgtgaatg aggctcttcg tcacaatgcc
     1081 tcacgtacgc cttcagcaac agagcttgct catgctaata atgcagctat gcaggcggaa
     1141 gcagagcgtt tgcgccttgc gaaagcagaa gaaaaagccc gtaaagaagc ggaagcagca
     1201 gaaaaggctt ttcaggaagc agaacaacga cgtaaagaga ttgaacggga gaaggctgaa
     1261 acagaacgcc agttgaaact ggctgaagct gaagagaaac gactggctgc attgagtgaa
     1321 gaagctaaag ctgttgagat cgcccaaaaa aaactttctg ctgcacaatc tgaagtggtg
     1381 aaaatggatg gagagattaa gactctcaat tctcgtttaa gctccagtat ccatgcccgt
     1441 gatgcagaaa tgaaaacgct cgctggaaaa cgaaatgaac tggctcaggc atccgctaaa
     1501 tataaagaac tggatgagct ggtcaaaaaa ctatcaccaa gagccaatga tccgcttcag
     1561 aaccgtcctt tttttgaagc aaccagacga cgggttgggg ccggtaagat tagagaagaa
     1621 aaacaaaaac aggtaacagc atcagaaaca cgtattaacc ggataaatgc tgatataact
     1681 cagatccaga aggctatttc tcaggtcagt aataatcgta atgccggtat cgctcgtgtt
     1741 catgaagctg aagaaaattt gaaaaaagca cagaataatc tccttaattc acagattaag
     1801 gatgctgttg atgcaacagt tagcttttat caaacgctga ctgaaaaata tggtgaaaaa
     1861 tattcgaaaa tggcacagga acttgctgat aagtctaaag gtaagaaaat cggcaatgtg
     1921 aatgaagctc tcgctgcttt tgaaaaatac aaggatgttt taaataagaa attcagcaaa
     1981 gccgatcgtg atgctatttt taatgcgttg gcatcggtga agtatgatga ctgggctaaa
     2041 catttagatc agtttgccaa gtacttgaag attacggggc atgtttcttt tggatatgat
     2101 gtggtatctg atatcctaaa aattaaggat acaggtgact ggaagccact atttcttaca
     2161 ttagagaaga aagctgcaga tgcaggggtg agttatgttg ttgctttact ttttagcttg
     2221 cttgctggaa ctacattagg tatttggggt attgctattg ttacaggaat tctatgctcc
     2281 tatattgata agaataaact taatactata aatgaggtgt tagggattta attattcttt
     2341 attgatataa aaagtcctag caatccaaat gggattgcta ggaccaaaca aagtagatta
     2401 tatagcataa ataggtttaa ttttgctacg ggggcgttat ttaggttttt tcttctttcg
     2461 aaaaaatctt tctttatgaa gttaaaagct atgtgttcaa tagcatattt tgaatatgga
     2521 catagaatag tgcttatcac tattgcatat agcatcttat ctgacacaag gaaataatac
     2581 ccttcgctgt tttttgttat aaggtatata tatataagtg tgcagtacag gccaaataaa
     2641 atatttttta tgtagtatct taagctcata aattaaacct cgccatatat tcttttcatt
     2701 ttataaggat cgagttatga ggaaaagatt ttttgtggga atattcgcga taaacctcct
     2761 tgttggatgt caggctaact atatacgtga tgttcaggga gggaccatcg caccatcctc
     2821 ctcttctaaa ctgacgggga tcgcggttca gtagaaaaga tcaaaggatc ttcttgagat
     2881 cctttttttc tgcgcgtaat ctgctgcttg caaacaaaaa aaccaccgct accaacggtg
     2941 gtttgtttgc cggatcaaga gctaccaact ctttttccga aggtaactgg cttcagcaga
     3001 gcgcagatac caaatactgt ccttctagtg tagccgtagt cgggccacta cttcaagaac
     3061 tctgtagcac cgtttgtgcc atcatcgctc tgctaatccg gttaccagtg gctgctgcca
     3121 gtggcgttaa ggcgtgcctt accgggttgg actcaagacg atagttaccg gataaggcgc
     3181 agcggtcggg ctgaacgggg ggttcgtgca cacagcccag cttggagcga acgacctaca
     3241 ccgaactgag ataccaacag cgtgagctat gagaaagcgc cacgcttccc gaagggagaa
     3301 aggcggacag gtatccggta agcggcaggg tcggaacagg agagcgcacg agggagcttc
     3361 cagggggaaa cgcctggtat ctttatagtc ctgtcgggtt tcgccacctc tgacttgagc
     3421 gtcgattttt gtgatgctcg tcaggggggc ggagcctatg gaaaaacgcc tgctacgtgg
     3481 ccttcttcct gttcctggtc ttttgctcac atgttctttc cggccttatc ccctgattct
     3541 gtggataact gtgttaccgt ttttgtgtga gtcagtaccg ctcgccgcag tcgaacgacc
     3601 gagcgtagcg agtcagtgag cgaggaagcg gaaaagcgcc tggacgtgca ttttctcctt
     3661 acgcatctgt gcggcatttc acacccggca tggcgtactt ttcatacaat ccgcactgat
     3721 gccgcatggt taagccagta tacactccgc tatcgctacg tgactgggtc agggcttcgc
     3781 cccgacaccc gctaaaacct gctgacgcgc cctgacgggc ttgtcagctc ccggcatccg
     3841 ctcacagaca agctgtgacc gtctccggga gctgcatgta tcagaggttt tcaccgtcat
     3901 ccccgaaacg tgcgaggcag ctgcggtaaa gctcatcggc gtggtcgtga agcgattcac
     3961 aaatatcggc ctgttcatct gcgtccagtt cgttgagctt ctccagcagc gttaatgtct
     4021 ggcttctgat aaagcgggcc atgttaaggg cggttttttc ctgtttagtc actgatgcct
     4081 ccgtgtaagg gggatttctg ttcatggggt aatgataccg atgaaacgcg agaggatgct
     4141 cacaatacgg gttactgatg atgaacatgc ccggttactt gaacgctgtg agggtaaaca
     4201 actggcggta tggatgcggc gggtctgcct gggggagccg gttgcccgtt ccggaaaact
     4261 gccgacactg gcaccgccgt tactgcgtca gctggccgcc atcggaaata acctgaatca
     4321 gacagcccgt aaggtgaaca gcgggcagtg gtcttccggt gaccgggttc aggtggtggc
     4381 cgcactgatg gccatcgggg atgagctgcg ccggctgcgt ctggccgtca gggaacaggg
     4441 ggcgcgggat gatagttaaa tttcatgcca ggggaaaagg tggtggcagt ggtccggttg
     4501 attacctgct ggggagggag cgtaaccgcg aaggcgcaac ggtgcttcag ggtaatccgg
     4561 aagaagtccg ggaactcatc gatgccacgc catttgcgaa gaaatacacg tccggtgttc
     4621 tgtcgttcgc ggagaaggag ctgccgccgg gaggacgtga aaaagtgatg gcgagctttg
     4681 agcgtgtact gatgcccggt ctcgaaaaaa atcagtacag catcctgtgg gtggagcacc
     4741 aggacaaggg acggcttgag ctgaattttg tcattccgaa catggagcta cagaccggaa
     4801 aacgcctcca gccgtactac gaccgcgcag acaggcctag aattgatgcc tggcagacgc
     4861 tggtgaatca ccattacggg ctgcatgacc cgaacgcccc ggagaaccgc aggacgctga
     4921 cactccctga taacctgcct gaaacgaaac aggcgcttgc tgagggcgtc acgcgaggta
     4981 tagatgcact ttaccatgcc ggagagataa aaggccgtca ggatgtgatt caggcgctca
     5041 ctgaggcggg gctggaagtg gtcagggtga cgcgaagcag tatcagcatt gcagatccga
     5101 acggcgggaa gaatatcagg ctgaaaggag cattttatga gcaatctttt gcagacgggc
     5161 gcggagttcg agaaaaagct gaaagagaga gccgaatcta cagagaaaat gctgaacaac
     5221 gagttcagga ggctcggcga atctgtaagc gaggctgtga catcaaacga gacgaaaatc
     5281 agagacgcta tagccctgtt cacagcctcg acagaggaat cgctggaaaa acaccgggaa
     5341 ggggtgaaag aggcgatgat gcagcacagg agggacgtgt taaagctggc agggaatacg
     5401 ggcatgatgt tactggggat agtatttctc ctgtttaccg cgagtggcgg gacgctctgg
     5461 tatcttggag ggaggataca ggcgaacctg gaagaaatca ggaagcagga agagacattg
     5521 cagaaactga acgcgaagac atggggcgtg gagtttgtgc aggacgggaa caggaaattc
     5581 cttgtccttc cgtacgggaa atcagcggag gtgattccct ttcaggggaa agagtgggta
     5641 catctgaagg agtgacacag agtgacagag ctggaaacac atttgctgaa cgccttagag
     5701 cagctgcaac aggactatat gcagcggctg agcgaatggg agagcgcctt cgtggaattg
     5761 cagaagatgt tttcgcttac gcaacgggac aacgcgatgc tgaacgagcg ggtcatgcag
     5821 ttgagtcagc aggtgcagca cttgagcgag cagacagaac gcttgagcca gttatacagc
     5881 gagaactgga gataagagag gaacggctga tacaggagcg cgaacatgtg ttatccctgg
     5941 aacgggagcg tcagccggaa atacaggaac gcacgctgga tggcccttcg ctgggatggt
     6001 gaaaccatga aaaatggcag cttcagtgga ttaagtgggg gtaatgtggc ctgtaccctc
     6061 tggttgcata ggtattcata cggttaaaat ttatcaggcg cgatcgcggc agtttttcgg
     6121 gtggtttgtt gccattttta cctgtctgct gccgtgatcg cgctgaacgc gttttagcgg
     6181 tgcgtacaat taagggatta tggtaaatcc acttactgtc tgccctcgta gccatcgaga
     6241 taaaccgcag aaatcgtgtc agccagcagc ctggattttt tcggggtaag gtctttgctg
     6301 cggtaatcag tacccgcaaa ttgagttgtg ccccggagtg agtttaaaaa ttcctggctg
     6361 tgaaactgct gaatgcgttg ttgcacatca ctccgtgatt ttcctgtcgc tttatcttta
     6421 gctcccatat cccagaactg ccgaaaaaaa ggcaccatca ttcgtgttgt gtcggctttt
     6481 tgggtggaaa agttgggatc aaaaccgtca tcagaagcat atacgtaatg ccgggtatgt
     6541 tgttccacgc tgccctttgg ggtacaggct gtgagagcta ctgttgctgt tatcatggcg
     6601 ataagacaaa gtttgtttcc ggtacgtctc atgagtgtct ccctacc
//
