LOCUS       CP088358               22029 bp    DNA     circular BCT 09-DEC-2021
DEFINITION  Escherichia coli strain F17EC0098 plasmid pF17EC0098-2, complete
            sequence.
ACCESSION   CP088358
VERSION     CP088358.1
DBLINK      BioProject: PRJNA782071
            BioSample: SAMN23391703
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22029)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Chromosomal integration and amplification of group 9 blaCTX-M genes
            in Escherichia coli expand the spectrum of resistance under
            antimicrobial pressure
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22029)
  AUTHORS   Yoon,E.-J., Choi,Y.J., Kim,D., Won,D., Choi,J.R. and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, Gangnam Severance Hospital,
            Yonsei, Seoul 06273, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other: SMRTLink v. v9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 133x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 12/02/2021 11:35:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,511
            CDSs (total)                      :: 5,393
            Genes (coding)                    :: 5,095
            CDSs (with protein)               :: 5,095
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 298
            CDSs (without protein)            :: 298
            Pseudo Genes (ambiguous residues) :: 0 of 298
            Pseudo Genes (frameshifted)       :: 130 of 298
            Pseudo Genes (incomplete)         :: 213 of 298
            Pseudo Genes (internal stop)      :: 55 of 298
            Pseudo Genes (multiple problems)  :: 85 of 298
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..22029
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="F17EC0098"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pF17EC0098-2"
                     /geo_loc_name="South Korea"
                     /lat_lon="35.18 N 129.08 E"
                     /collection_date="2017"
                     /collected_by="Kor-GLASS"
     gene            join(21305..22029,1..3)
                     /locus_tag="LQQ82_27325"
                     /pseudo=""
     CDS             join(21305..22029,1..3)
                     /locus_tag="LQQ82_27325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /name="endonuclease/exonuclease/phosphatase family protein"
     gene            2..456
                     /locus_tag="LQQ82_27330"
                     /pseudo=""
     CDS             2..456
                     /locus_tag="LQQ82_27330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="catalyzes the formation of asparagine from aspartate
                     and ammonia; frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase A"
                     /name="asparagine synthetase A"
     gene            complement(461..1912)
                     /gene="viaA"
                     /locus_tag="LQQ82_27335"
                     /pseudo=""
     CDS             complement(461..1912)
                     /gene="viaA"
                     /locus_tag="LQQ82_27335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /name="viaA"
     gene            complement(1906..3403)
                     /gene="ravA"
                     /locus_tag="LQQ82_27340"
                     /pseudo=""
     CDS             complement(1906..3403)
                     /gene="ravA"
                     /locus_tag="LQQ82_27340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312715.2"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /name="ravA"
     gene            3626..5302
                     /gene="kup"
                     /locus_tag="LQQ82_27345"
                     /pseudo=""
     CDS             3626..5302
                     /gene="kup"
                     /locus_tag="LQQ82_27345"
                     /inference="COORDINATES: protein motif:HMM:NF014731.2"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /name="kup"
     gene            5311..5490
                     /locus_tag="LQQ82_27350"
     CDS             5311..5490
                     /locus_tag="LQQ82_27350"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGD37927.1"
                     /translation="MMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEI
                     PPNRVIELGTQVEI"
                     /name="hypothetical protein"
     gene            5683..6073
                     /gene="rbsD"
                     /locus_tag="LQQ82_27355"
                     /pseudo=""
     CDS             5683..6073
                     /gene="rbsD"
                     /locus_tag="LQQ82_27355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /name="rbsD"
     gene            6081..7582
                     /gene="rbsA"
                     /locus_tag="LQQ82_27360"
                     /pseudo=""
     CDS             6081..7582
                     /gene="rbsA"
                     /locus_tag="LQQ82_27360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /name="rbsA"
     gene            7587..7775
                     /locus_tag="LQQ82_27365"
     CDS             7587..7775
                     /locus_tag="LQQ82_27365"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGD37928.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINN
                     LFNILQQTSVNAIWRSG"
                     /name="hypothetical protein"
     gene            7772..8029
                     /locus_tag="LQQ82_27370"
     CDS             7772..8029
                     /locus_tag="LQQ82_27370"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UGD37929.1"
                     /translation="MTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALAL
                     GAAIGAVTGCDCSERAGPGVYRYAGYDAFTARRDHGLYQW"
                     /name="hypothetical protein"
     gene            8149..8620
                     /locus_tag="LQQ82_27375"
                     /pseudo=""
     CDS             8149..8620
                     /locus_tag="LQQ82_27375"
                     /inference="COORDINATES: protein motif:HMM:NF014684.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            8644..9462
                     /gene="rbsB"
                     /locus_tag="LQQ82_27380"
                     /pseudo=""
     CDS             8644..9462
                     /gene="rbsB"
                     /locus_tag="LQQ82_27380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001575185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /name="rbsB"
     gene            9587..10500
                     /gene="rbsK"
                     /locus_tag="LQQ82_27385"
                     /pseudo=""
     CDS             9587..10500
                     /gene="rbsK"
                     /locus_tag="LQQ82_27385"
                     /inference="COORDINATES: protein motif:HMM:NF012515.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /name="rbsK"
     gene            10518..11516
                     /gene="rbsR"
                     /locus_tag="LQQ82_27390"
                     /pseudo=""
     CDS             10518..11516
                     /gene="rbsR"
                     /locus_tag="LQQ82_27390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /name="rbsR"
     gene            complement(11696..12559)
                     /locus_tag="LQQ82_27395"
     CDS             complement(11696..12559)
                     /locus_tag="LQQ82_27395"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="UGD37925.1"
                     /translation="MPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPFLAACWSPG
                     QPGMDIFNQYPHRYCGPSLRAQTYAQFHHRTTQIRYHWLFAVWLSLVLFSSGIELFGEK
                     IVASWIALTVIVTSIWLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRLGTGC
                     VPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGITVIIG
                     LMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGNSVLAVT
                     QQLLSV"
                     /name="MFS transporter"
     gene            complement(12516..12881)
                     /locus_tag="LQQ82_27400"
     CDS             complement(12516..12881)
                     /locus_tag="LQQ82_27400"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="UGD37926.1"
                     /translation="MAGLPWIAAMAFFMQALDATILNTALPAIAHSLIVLLSRCNQPSS
                     VYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQLVVFRVIQGIG
                     GAMDACCSAGLTARLSS"
                     /name="MFS transporter"
     gene            complement(12927..13622)
                     /locus_tag="LQQ82_27405"
                     /pseudo=""
     CDS             complement(12927..13622)
                     /locus_tag="LQQ82_27405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /name="FadR family transcriptional regulator"
     gene            14094..15612
                     /locus_tag="LQQ82_27410"
     rRNA            14094..15612
                     /locus_tag="LQQ82_27410"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
                     /name="16S ribosomal RNA"
     gene            15698..15772
                     /locus_tag="LQQ82_27415"
     tRNA            15698..15772
                     /locus_tag="LQQ82_27415"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15731..15733,aa:Glu,seq:ttc)
                     /name="tRNA-Glu"
     gene            15962..18855
                     /locus_tag="LQQ82_27420"
     rRNA            15962..18855
                     /locus_tag="LQQ82_27420"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
                     /name="23S ribosomal RNA"
     gene            18957..19069
                     /gene="rrf"
                     /locus_tag="LQQ82_27425"
     rRNA            18957..19069
                     /gene="rrf"
                     /locus_tag="LQQ82_27425"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
                     /name="rrf"
     gene            19125..19201
                     /locus_tag="LQQ82_27430"
     tRNA            19125..19201
                     /locus_tag="LQQ82_27430"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19159..19161,aa:Asp,seq:gtc)
                     /name="tRNA-Asp"
     gene            19377..20164
                     /gene="dkgB"
                     /locus_tag="LQQ82_27435"
                     /pseudo=""
     CDS             19377..20164
                     /gene="dkgB"
                     /locus_tag="LQQ82_27435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /name="dkgB"
     gene            complement(20161..21071)
                     /locus_tag="LQQ82_27440"
                     /pseudo=""
     CDS             complement(20161..21071)
                     /locus_tag="LQQ82_27440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing protein"
                     /name="LysR substrate-binding domain-containing protein"
ORIGIN
        1 tctcgatgcc aaagggcgtg agcggcgatt gcgaaagatc ttggcgcggt attcctcgtc
       61 gggattggcg gcaagttgag tgatggtcat cgtcacgacg tgcgcgcacc ggattatgat
      121 gactggagca ccccgtcaga gctgggccat gcgggtctga acggcgatat tctggtgtgg
      181 aacccggtac tggaagatgc gtttggactt tcttccatgg ggatccgcgt ggatgccgaa
      241 cacgctgaag catcagctgc gctgaccgtg acgaagatcg cctggagctg gagtggcatc
      301 aggcgctgct gcgcggtgaa atgccgcaga ccatcggcgg cggtatcggg cagtctcgtt
      361 tgaccatgct gctgctgcaa ctgccacata tcggccaggt tcagtgtggg tgtatggccg
      421 gcagctgttc gcgagagcgt cccttctctg ctgtaataat ttatcgccgc cagcgtctga
      481 gcagcggcgg cttcgcatcc cggtatcaaa gcgccagatg tgatcgaaaa tgcgcatgat
      541 gccgggtttg ccatgtgcag acatcgccac aggcatgaaa gcgatgctga tgtacccgct
      601 gtaggctctt tcactttctc gtcacgtcgt caggcaaccg ctgggcgata aatcagaaat
      661 caccaccgca tcggcatcaa ccattcccgg ctttgcaagc gttccataat ggcgcgaaac
      721 aactggcaag atcggtgcgc cacgaaactg ctgacttaaa aaacggattg cttgttcgat
      781 gccttgtggg cctgaaagct cataacgact aatctcggtg gaaaatagca taatatagca
      841 gcgccggttt tcagcgagag caatgcgcat caaggccagg cagaacgctt tcgcacactg
      901 ttcattaaag ccgcccattg agccggaagt atccacacag acaataaacg gtccgcgcgg
      961 ctgttcgtcg taatctttat gcaccaccgg gcgttcgatc actttttcac gccacgactc
     1021 accatgcagg cgataggtga gcaactgttt ttccacagcc gacggtaaaa ctcatactcc
     1081 agttctgtta tccctagtgt cgccagttct ggcggcagga gacgtaaaat atcatcgctt
     1141 tgttgcagac catcaacctg ctcaggaacc gtcgccggtt cgcgcaccat gcggaaggtt
     1201 tccatctgcg catcgttgcg cggtattgat ttggcttccc gggaacgccc cagctgttct
     1261 gccaggcgtt tcagttccgg ctgttcgtta agaaattcac cgtatttcac aatcaactga
     1321 tagtcgccac gtttaagctg accggcgctc atatcccaca gacgaccagc tgcggtattg
     1381 ttatctgaga gaatcggttt caagttgtcc gctcagcgtc atgcgttcct gaacttcact
     1441 caacagttgt tcgcgtttct tcttcttaat agctgttgat ttaacgtcgt tgcttgcacg
     1501 attcagactt aaacgccaac gctggagaaa aagcgtgtgt aacgctgaag tgatcgtgct
     1561 gtttagcata accaactgtc gggcttgttc tgcccatggg gaattcagac gatgcagtag
     1621 tccaggatct gtggtagctg cacaataaac tgcggcgtgg agaggagctg gctttgctga
     1681 tagcacatca cctcttcggt gagttccggc gggactcggg catctttcag ccgactgcgc
     1741 agcgccatca cgccagcggg gaacatcatc agtgattgcc gccttcagtc gtgggaattt
     1801 ttcaaagaag actgcctact gcgtgtgagg ccagcagcgc gatgatttca tctcttcgtc
     1861 aatccctctt cgctgacggc cagcatcaat taagcgtatc cagcgttagc attgttgtgc
     1921 ctggcgaatc tgtgcgccga catcctgtag gctggcttca atgcgaccta accagtcgcc
     1981 agggataaac agacattttt gctgttcgct gaataaagcg tgttgcttgc gccagtcgct
     2041 ttcaagctct tccagttgtt gttttatttc acctggcaga ccttcagccg atgaaccggg
     2101 aagtgccgcg tactgccttg taaacttaca tcgcgtacaa caagatgttg ggcgcctatc
     2161 cttccagatt cagtttctgg gcaaagccga taccgttcag tttgccgcga atctcaccac
     2221 ctttactcag ccactgttcc agcgcgctac gctcaaagga gatatgaacc acttccatat
     2281 catgcaattt taacggtttt tgcagcagca gagtcagagt ggaagcagta acgttaacag
     2341 gaagttgata ctgctgacga cggctgaaaa tgccgcccag acgaattacc gttaaggctg
     2401 ttttatcgct ttgttgcttg ctggagttca ggtgacgttg cacaatcgcg ccaggcgggt
     2461 caacatcccc tttgctgttg cccggcatga ccggtcatca atacatcaat ttgttgttgt
     2521 atcaaattca ggctttgcgc gtcataccac agcaatcttc agcaaaatga gatcaaccgg
     2581 gcaacagcac tgcgaccgct aaaaaaggcg ctggcctgca ataagcggat cgcttttttc
     2641 cagcgacgat ccgagacata aggctcatcc ggtaatttat ccagttgctg gcgcagcata
     2701 aaaatcagct caaatacatg atcgggcagc gtaatttcac caatctcttt ctgccagcgt
     2761 tcatattctt catctgtgat ctgcaaggag gcaggaaccg gattgtcatt ttcatcctgt
     2821 tgactgtgca gcatggagcg cgaaattcgc tttatcctgc actttatcta accacagacg
     2881 aatccagcat gcggtcatat aacgcttcca gactgctgtc tgcttccggc agctcgttgg
     2941 aggccgccac cagcagacgc atcgggattt tttctacgag tgcgccgttg cggaactggc
     3001 gctcgttaat ggcggtgagc aaggtattaa gaattgccgg acccgctttc cagagatctc
     3061 atccagaaag acgatttcag cttccggcag tgtaaccgct ggttaaacgt tcatagcgcc
     3121 cttcatcttt tagcgcctga atagaaaggg gaccaaaaaa cttcttccgg cgtggagaag
     3181 cgggtcatca gatattcaaa cgcgcggggc attctgaaag gcgaatttta agcgccgggc
     3241 gatcaaactt ttggcaatac ctggtgggcc aaggaggaac acacttcacc acttaatgcc
     3301 gctaataaac acaagcggat ggcgtggcta cgttcataaa gcccctttcc aacgaactgc
     3361 tcaggcggga aattctttcc gctaataaat gagggtgagc cataatgaag tggcgtcctt
     3421 tcacaaaagt tctgcgtaaa ttgcgagtat agacgtttct tgctggtggc taaaatagtc
     3481 tcaaaggagg ggtatttttc tttgagccag gttaatgtgg ccgcatttag gagtacgatt
     3541 ttgccgttaa tcgtgcatac tgtgcgcttt tttgtgggcc aagggactaa gcacacattt
     3601 tcatatttca acgaaagact agtctatgag cactgataat aagcaatcat tgcccgcgat
     3661 taccctcgcg gcgattggag ttgtctacgg cgatattggt accagcccgt tatatacact
     3721 tcgtgaatgt ttgtccggcc agtttggttt tggcgttgaa cgcgatgccg tgtttggctt
     3781 tttatcgctg atctttctgg ctgctaatct ttgtggtttc cattaaatat ctcaccttcg
     3841 tgatgcgggc agataaacgc cggtgaaggg gggatcctga cgttgatgtc gcttgcgggc
     3901 gtaatacgtc ggcgcgaacc acatcaatgc tggtgattat ggggctaatc ggcggcagct
     3961 ttttctatgg tgaagtcgtc attactcccg ctatttcggt gatgtccgcc attgaaggtc
     4021 tggaaatcgt cgccccgcag ctggatacct ggatagttcc cctctcaatt atcgttctca
     4081 cattattatt catgattcaa aaacatggca cagctatggt cggtaagctg tttgcgccga
     4141 tcatgctgac ctggtttttg attctggcag ggctggggtt tacgtagcat tattgctaac
     4201 ccggaagtgc tgcatgcact gaatccgatg tgggcggtgc atttcttcct tgaatacaaa
     4261 acggtttctt ttattgcatt ggggcagtgg tgctgtcgat tacggggtcg aggcgctgta
     4321 tgctgatatg gggcactttg gtaagttccc tattcgtctg gcgtggttca ccgtcgtatt
     4381 gccttcctta acccttaatt acttcggcag ggagcgctgt tgttaaagaa tccggaagcg
     4441 attaagaacc cgttcttcct gttggcaccg gactgggcgc tgatcccgct gctgatcatc
     4501 gccgcactgg cgacggtaat tgcctcgcag gcggttatct ctggcgtctt ctcattgacg
     4561 cgtcaggcgg tacgtctggg atatttgtcg ccgatgcgca ttattcacac ctccgaaatg
     4621 gagtcagggc aaatctatat tccctttgtg aactggatgc tctatgtcgc ggtcgtgatt
     4681 gtgattgtca gctttgagca ctccagcaac ctggcggcgg cgtacgggat tgcggtgacc
     4741 ggaaccatgg tgctgacgtc tattctctcg actaccgtgg cacgtcagaa ctggcactgg
     4801 aataagtatt ttgttgcgct gatcctgatt gctttccttt gtgtcgatat tcccttgttc
     4861 accgctaacc tcgataaact gctctccggt ggctggttgc cattgagcct cggtacggtg
     4921 atgtttatcg tgatgaccac ctggaagagc gagctttccg cttgctgcgg cggatgcatg
     4981 aacatggtaa ctctctggaa gcgatgattg cttcgctgga gaaatcaccg ccgttcgcgt
     5041 gcctgggacc gcggtgtata tgtcgcgtgc aatcaacgtc attccctttg cgctgatgca
     5101 taaccttaaa cataacaagg tattgcatga gcgggtgatt ctgttaactc tgcgcaccga
     5161 agacgcgcca tatgtccata acgtccgtcg ggtacagatt gaacaactgt cgccactttc
     5221 tggcgcgtgg tggcaagtta tggttggcga gaaacgccaa acgtggaaga agttttccac
     5281 cgctgcggtc tggaaggatt aagctgccgg atgatggaaa cctccttctt tatgtcgcat
     5341 gagtcgttga tcctcggcaa acgcccgtgg tatttgcgtc tgcgcggcaa gctgtacttg
     5401 ctgctgcaac gtaatgcgct gcgggcaccg gatcaatttg aaatcccgcc aaacagagtt
     5461 atcgaactgg gtactcaggt cgaaatctaa cgccagacgc ctcctttctc ataagggggc
     5521 gtttttgttt tcatggttaa tcaccatgta aaacgtttcg aggttgatca catttccgta
     5581 acgtcacgat ggttttccaa ctcagtcagg attaaactgc gggtcagcga aacgtttcgc
     5641 tgatggagaa aaaaagaaaa aggcaccgtt cttaattctg atatttcatc ggtgatctcc
     5701 cgactgggac ataccgatac gctggtggtg tgtgatgctg gtttcccatc cccaaaaagt
     5761 acaacgcgta tcgatatggc attaacccag ggtgtacctt cttttatgca ggtgctgggc
     5821 gtcgtcacaa atgaaatgca ggtcgaggct gtcattatcg cggaagagat caaacaacat
     5881 aatccgcaac tccacgaaac gtttgctcac tcaccttgag cagctgcaac aacaccaggg
     5941 aaacaccatt gaaattcgtt acaccacgca tgaacaattc aaacaacaaa ccgcagaaag
     6001 tcaggcggta attcgcagcg gagaatgttc tccgtatgcg aatatcattc tctgtgctgg
     6061 cgtgacgttc tgaggccgtc atggaagcat tacttcagct taaaggcatc gataaagcct
     6121 ttccgggcgt aaaagccctc tcgggcgcag cgtaaatgtc tatccgggcc gcgtgatggc
     6181 gctggtgggc gaaaacggcg cgggtaaatc caccatgatg aaagtgctta ctggtatcta
     6241 tactcgcgat gccggtacgc ttttatggtt ggggaaagaa acgacattta ccgggccgaa
     6301 atcttcccag gaagccggga ttgggattat ccaccaggaa ctgaacctga ctcccgcagt
     6361 taaccattgc cgaaaacatt ttcctcggtc gtgagtttgt taatcgcttt ggcaaaattg
     6421 actggaaaac catgtatgcc gaagcggata aattgctggc taaacttaac ctgcgcttta
     6481 aaagcgacaa actggtgggt gatctttcca tcggtgacca gcaaatggtt gaaatcgcca
     6541 aagtgctgag ctttgagtcg aaagtcatca ttatggatga accgaccgat gcgctgaccg
     6601 ataccgaaac cgaatccttg ttccgcgtca tccgcgagct gaaattgcaa ggccgcggta
     6661 ttgtctatat ctcccaccgc atgaaagaaa tcttcgagat ttgcgatgac gttaccgttt
     6721 ttcgtgacgg acaatttatt gctgagcgtg aagtggcatc actgaccgaa gattctctga
     6781 ttgagatgat ggtgggccgc aagctggaag atcaatatcc gcacctggac aaagcgccgg
     6841 gagatatccg cctgaaagtc gataatctct gcggacctgg cgttaacgat gtctctttta
     6901 ctttacgcaa aggcgaaatt cttggcgtct ctggtttgat gggcgctggc gtaccgaact
     6961 gatgaaagtg ctctacggcg cactgccgcg cacaagcggt tacgtcaccc tggatgggca
     7021 tgaagtcgtt acccgttcgc cgcaggatgg cctggcaaac ggcattgttt atatctccga
     7081 agaccgtaaa cgtgacggtt tagtgctggg catgtcagta aaagagaaca tgtcgctgac
     7141 cgcgctgcgc tacttcagcc gcgctggcgg cagtttgaag catgccgatg aacagcaggc
     7201 tgtgagtgat ttcattcgtc tgtttaatgt gaaaacgcca tcgatggaac aggcaattgg
     7261 tctgctttcc ggtggcaatc agcaaaaagt agcgattgcc cgtggtctga tgacacgccc
     7321 taaagtgttg atctcgatga gcctacccgt ggcgtagatg tcggcgcgaa aaaagagatc
     7381 tatcaactga ttaaccagtt caaagccgat ggcttgagca tcattctgtg tcatcggaga
     7441 tgccagaagt attaggcatg agcgatcgca tcatcgtcat gcatgaaggg catctcagcg
     7501 gggaatttac tcgtgagcag gccacccaag aagtgttaat ggctgccgcg tgggcaagct
     7561 taatcgcgtg aatcaggagt aaaaaaatga caacccagac tgtctctggt cgccgttatt
     7621 tcacgaaagc gtggctgatg gagcagaaat cgcttatcgc tctgctggtg ctgatcgcga
     7681 ttgtctcgac gttaagcccg aactttttca ccatcaataa cttattcaat attcttcagc
     7741 aaacctcggt gaacgccata tggcggtcgg gatgacgctg gtgatcctga cgtcgggtat
     7801 cgacttgtcg gtaggttctc tgttggcgct gaccggcgca gttgctgcat ctatcgtcgg
     7861 cattgaagtc aatgcgctgg tggctgtcgc tgccgctctc gcgttaggtg ccgcaattgg
     7921 tgcggtaact gggtgtgatt gtagcgaaag ggccggtcca ggcgtttatc gctacgctgg
     7981 ttatgatgct tttactgcgc ggcgtgacca tggtttatac caatggtagc ccagtgaata
     8041 ccggctttac tgagaacgcc gatctgtttg ctggtttggt attggtcgtc cgctgggcgt
     8101 accgacgcca gtctggatca tgggttgatc ttcctcgcgg cctggtacat gctgcatcac
     8161 acgcgtctgg ggcgttacat ctacgcgctg ggcggcaacg aagcggcaac gcgtctttct
     8221 ggtatcaacg tcaataaaat caaatcatcg tctattctct ttgtggtctg ctggcatcgc
     8281 tggccggatc attgaagtgg cgcgtctctc ctccgcacaa cccacggcgg ggactggcta
     8341 tgagctggat gctattgctg cggtggttct gggcggtacg agtctggcgg gcggaaaagg
     8401 tcgcattgtt gggacgttga tcggcgcatt aattcttggc ttccttaata atggattgaa
     8461 tttgttaggt gtttctctat taccagatga tcgtcaaagc ggtggtgatt ttgctgctgc
     8521 gtgctgtaga caacaaaaag cagtaataac gactacagga catcttgaat atgaacatga
     8581 aaaaaaaaac tggctaccct ggtttccgct gttgcgctaa gcgccaccgt cagtgcgaat
     8641 gcgatggcaa aagacaccat cgcgctggtg gtctccacgc ttaacaaccc gttctttgta
     8701 tcgctgaaag atggcgcgca gaaagaggcg gataaacttg gctatacctg gtggtgctgg
     8761 atcccagaac aacccggcga aagagctggc gaaacgtgca ggacttaacc gtccgcggca
     8821 ccaaaattct gctgaaaccc gaccgactcc gacgcagtag gtaatgctgt gaagatggct
     8881 aaccaggcga acatcccggt tatcactctt gaccgccagg caacgaaagg tgaagtggtg
     8941 agccacatcg catctgataa cgtactgggc ggcaaaatcg ccggtgatta catcgcgaag
     9001 aaagcgggtg aaggtgccaa agttatcgag ctgcaaggca ttgccggtac atccgcagcc
     9061 cgtgaacgtg gcgaaggttt ccagcaggcc gttgctgctc acaagtttaa tgttcttgcc
     9121 agccagcctg cagattttga tcgcaccaaa ggcttgaacg taatgcagaa cctgttgacc
     9181 gctcatccgg atgttcaggc tgtattcgcg cagaatgatg aaatggcgct tggcgcgctg
     9241 cgcgcactgc aaactgccgg taaatcggat gtgatggtcg tcggatttga cggtacaccg
     9301 gatggcgaaa aagcggtgaa tgatggcaaa ctagcagcga ctatcgctca gctacccgat
     9361 cagattggcg cgaaaggcgt cgaaaccgca gataaagtgc tgaaaggaga gaaagttcag
     9421 gctaagtatc cggttgatct gaaactggtt gttaagcagt agttttaatc aggttgtatg
     9481 acctgatggt gacataaata cgtcatcgac agatgaacgt gtaatataaa gaaaagcagg
     9541 gcacgcgcca ccctaacacg gtggcgcatt tatggacatc ccgaatatgc aaaacgcagg
     9601 cagcctcgtt gttcttggca gcattaatgc tgaccacatt cttaatcttc aatcttttcc
     9661 tactccaggc gaaaccgtaa ccggtaacca ctatcaggtt gcatttggcg gcaaaggcgc
     9721 gaatcaggcg gtggctgctg ggcgtagcgg tgcgaatatc gcgtttattg cctgcactgg
     9781 cgatgacagc attggtgaga gcgttcgcca gcagctcgcc actgataata tcgatatttc
     9841 tccggtcagc gtgatcaaag gcgaatcaac aggtgtggcg ctgattttgt taatggcgaa
     9901 ggtgagaatg tcatcggtat tcatgccggc gctaatgctg ccctttcccc ggcgctggtg
     9961 gaagcgcaac gtgagcgtat tgccaacgcg tcggcattat taatgcagct ggaatcacca
    10021 ctcgaaagtg tgatggcagc ggcgaaaatc gcccatcaaa ataagactat cgttgcgctt
    10081 aacccggctc cggctcgcga acttcctgac gaacttctgg cgctggtgga cattattacg
    10141 ccaaacgaaa cggaagcaga aaagctcacc ggtattcgtg ttgaaaatga tgaagatgca
    10201 gcgaaggcgg cgcaggtact gcatgaaaaa ggtatccgta ctgtactgat tactttagga
    10261 agtcgtggtg tatgggctag cgtgaatggt gaaggtcagc gcgttcctgg attccgggtg
    10321 caggctgtcg ataccattgc tgccggagat acctttaacg gcgcgttaat cacggcgttg
    10381 ctgggaaaaa aaacattgcc agaggcgatt cgttttgccc atgcagccgc tgcgattgcc
    10441 gtaacacgta aaggcgcaca accttccgta ccgtggcgtg aagagatcga cgcattttag
    10501 acaggcagag gtgacgcttg gctacaatga aagatgttgc ccgcctggcg ggcgtttcta
    10561 cctcaacagt ttctcacgtt atcaataaag atcgcttcgt cagtgaagcg attacagcca
    10621 aagttgaagc ggcgattaaa gaactcaatt acgcgccatc agctctggcg cgtagcctca
    10681 aactcaatca aacacatacc attggcatgt tgatcactgc cagtaccaat cctttctatt
    10741 cagaactggt gcgtggcgtt gaacgcagct gcttcgaacg cggttatagt cttgtccttt
    10801 gcaataccga aggcgatgaa cagcggatga atcgtaatct ggaaacgctg atgcaaaaac
    10861 gcgttgatgg cttgctgtta ctgtgcaccg aaacgcatca gccttcgcgt gaaatcatgc
    10921 aacgttatcc gacagtgcct accgtgatga tggactgggc tccgttcgat ggcgacagcg
    10981 atcttattca ggataactcg ttgctggggg agaacttagc aacgcaatat ctgatcgata
    11041 aaggtcatac ccgtattgcc tgtattaccg gtccgctgga taaaaactcc ggcgcgccgc
    11101 tgcggttgga aggttatcgg gctgcgataa acgtgcgggt ctcaacattc ctgatggcta
    11161 tgaagtcact ggtgattttg aatttaacgg cgggtttgac gctatgcgcc aactgttatc
    11221 acatccgctg cgtcctcagg ccgtctttac cggaaatgac gctatggctg ttggcgttta
    11281 ccaggcgtta tatcaggcag agttacaggt tccgcaggat atcgcggctg gtgattggct
    11341 atgacgatat cgaactggca agctttatga cgccaccatt aacaactata caccaaccga
    11401 aagatgaact gggggagctg gcgattgatg tactcatcca tcggataacc cagccgaccc
    11461 tacagcaaca acgattacaa cttactccga ttctgatgga acgcggttcg gcttagattt
    11521 acgctgtctt ttgaatcaaa ttattaccat cggttgtttt cagtagcatg aacattgctg
    11581 ctgaagcaac agtaataatg cccatcgtga taaacgtata gtggaattgt tcgactgtcg
    11641 ttgtgccttc catcccttcg taaacgcgaa ggacggccgc acttacagca aacgcctaaa
    11701 ctgataacag ttgctgcgtg accgccagaa cactgttacc gctgctggcg ttgtcatcgg
    11761 tcagatcggc aagtgtgatg gtattcatcg cggtaaattg cgtcgacata gccatcccta
    11821 atataaacaa cggcaagatc agcatccata tcgccattgc tggtgattgc aaagagaact
    11881 gagcgatcat tagcccaata atcaccgtga tccccactaa cgtatggcga tagcccagac
    11941 gacgtaagac ttgggtaacc atcgattttg caataatgga acctaacgct gtcggtgcca
    12001 tcatacagcc agcaataaac gcctgatacc caaatcctac ctgtaacatc aatggcataa
    12061 ggaacggtac acagccggtc cccagacggg ttgcaatatt gcctacgata ccgatcgaga
    12121 aagtgcgggt tttaaataaa tctaatgaaa ttaatgggtt tggcgtgcgt cgcgcatgga
    12181 gaatatagag aagcagtaac cagatgctgg tgacaattac cgtcaaggca atccagctgg
    12241 cgacaatctt ttccccgaat agctctattc cgcttgagaa gagaacaagg ctgagccaaa
    12301 cagcaaaaag ccagtggtat cgaatctgcg tcgtgcggtg gtgaaattgg gcatatgttt
    12361 gcgcgcgtaa agaaggcccg caatacctat ggggatattg attaaaaata tccatgccag
    12421 gttgcccagg tgaccagcac gccgccaaga acgggcctaa aattggcccc accagacccg
    12481 gcatggcgac aaaattcaat acaggaagaa gttcattacg aggataagcg cgcagtaagg
    12541 ccagccgagc aacaggcatc cattgcgccg cctatcccct gaataacccg gaagacaacc
    12601 agctgtggta gcgagttgga aagtgcgcag gccagagaac ccaacgtgaa cagactcacg
    12661 gcaagggtaa aaatgcgacg cgtaccgaag cgatcggcta gccatccgct taccggaata
    12721 agcatcgcca ccgtcagcgt ataaactgat gatggctgat tgcatcgcga gaggagaacg
    12781 ataaggctat gagcgattgc gggtaaggcg gtattcagaa tagtggcatc aagtgcctgc
    12841 atgaagaagg ccatcgccgc gatccacggc aaacccgcca tactgcgctt cttttatcgc
    12901 tcattcaaag tcctgttatc gggttatcac ttatctggtg agcgtagcag cgcctgacaa
    12961 gctttaaatg ccgcgtcgcc atcgctttgg ataatcgtat cgacaatcgc ctggtgcaga
    13021 tccagcttta tcactgtgtc gctggtaatt gacgtgaagt aagtgtgata aaccgaatgg
    13081 aatagcgagg cgaatgaggt caaaaacgga ttggcgctca tttcatagat atgctcatgc
    13141 caggccatat cgacttcgat ccagcgttca cggcgaaagt tctcttttaa tgccgccatt
    13201 tcggccatta acgtattgag atgcgccttc tgttccgcgg tgccaaccgt tgctgccagt
    13261 aggcaagctt gcggctccag acagatacgc ataaccagaa agtgatcgat gacctgatga
    13321 aagttctctt ctgtcatcca ccaggtaagc aattcctgat caagaaaatt ccagttcgat
    13381 tgtggcatga ctcgggtacc aattcgcggt cgcggtaaaa ccatcccttt tgccgttaac
    13441 gttttgacgc cttcgcgtac cgctgtacga ctcactccaa attgctcgcc cagctcaatc
    13501 tcaccaggca aatgtgccgg gttcatattc accttttaag atccgctgcg ccagcttttc
    13561 agccagaaca tacgaaaggt tttctgtgca gctaactgtt gtgcgctaaa ggcattacta
    13621 atcttccttt tcttttattc ctccttagta tgccaccagg aagtgtgatt tacggttgca
    13681 aaacggcaaa ttgcttgttt tatggcacat taacggggct tttgctgaaa aaatgcgcgg
    13741 tcagaaaatt attttaaatt tcctcttgtc aggccggaat aactccctat aatgcgccac
    13801 cactgacacg gaacaacggc aaacacgccg ccgggtcagc gggattctcc tgagaattcc
    13861 ggcagagaaa gcaaaaataa atgcttgact ctgtagcggg agagcgtatt atgcaccccg
    13921 cgccgcccta agaaaaaacg aagcggcact gctctttaac aatttatcag acaatctgtg
    13981 tgggcactcg aagatacgga ttcttgacgt cgcaagacga aaaatgaata ccaagtctca
    14041 agagtgaaca cgtaattcat tacgaagttt aattctttga gcatcaaact tttaaattga
    14101 agagtttgat catggctcag attgaacgct ggcggcaggc ctaacacatg caagtcgaac
    14161 ggtaacagga acagcttgct gtttgctgac gagtggcgga cgggtgagta atgtctggga
    14221 aactgcctga tggaggggga taactactgg aaacggtagc taataccgca taacgtcgca
    14281 agaccaaaga gggggacctt cgggcctctt gccatcggat gtgcccagat gggattagct
    14341 agtaggtggg gtaacggctc acctaggcga cgatccctag ctggtctgag aggatgacca
    14401 gccacactgg aactgagaca cggtccagac tcctacggga ggcagcagtg gggaatattg
    14461 cacaatgggc gcaagcctga tgcagccatg ccgcgtgtat gaagaaggcc ttcggttgta
    14521 aagtactttc agcggggagg aagggagtaa agttaatacc tttgctcatt gacgttaccc
    14581 gcagaagaag caccggctaa ctccgtgcca gcagccgcgg taatacggag ggtgcaagcg
    14641 ttaatcggaa ttactgggcg taaagcgcac gcaggcggtt tgttaagtca gatgtgaaat
    14701 ccccggctca acctgggaac tgcatctgat actgcaagct tgagtctcgt agaggggggt
    14761 agaattccag gtgtagcggg tgaaatgcgt agagatctgg aggaataccg gtggcgaagg
    14821 cggccccctg acgaagactg acgctcaggt gcgaaagcgt ggggagcaaa caggattaga
    14881 taccctggta gtccacgccg taaacgatgt cgacttggag gttgtgccct tgaggcgtgg
    14941 cttccggagc taagctaagt cggttagtcg accgcctggg gagtacggcc gccgcaaggt
    15001 taaaactcaa atgaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
    15061 tgcaacgcga agaaccttac ctggtcttga catccacgga agttttcaga gatgagaatg
    15121 tgccttcggg aaccgtgaga caggtgctgc atggctgtcg tcagctcgtg ttgtgaaatg
    15181 ttgggttaag tcccgcaacg agcgcaacct tatcctttgt tgccagcgtc cggccgggaa
    15241 ctcaaaggag actgccagtg ataaactgga ggggagaagt ggggatgacg tgctacacac
    15301 gtgctacaat ggcgcataca aagagaagcg acctcgcgag agcaagcgga cctcataaag
    15361 tgcgtcgtag tccggattgg agtctgcaac tcgactccat gaagtcggaa tcgctagtaa
    15421 tcgtggatca gaatgccacg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca
    15481 ccatgggagt gggttgcaaa agaagtaggt agcttaacct tcgggagggc gcttaccact
    15541 ttgtgattca tgactggggt gaagtcgtaa caaggtaacc gtaggggaac ctgcggttgg
    15601 atcacctcct taccttaaag aagcgtactt tgcagtgctc acacagattg tctgatagaa
    15661 agtgaaaagc aaggcgtctt gcgaagcaga ctgatacgtc ccttcgtcta gaggcccagg
    15721 acaccgccct ttcacggcgg taacaggggt tcgaatcccc taggggacgc cacttgctgg
    15781 tttgtgagtg aaagtcacct gccttaatat ccaaaactca tcttcgggtg atgtttgaga
    15841 tatttgctct ttaaaatctg gatcaagctg aaaattgaaa cactgaacaa cgagagttgt
    15901 cggagtctct caaattttcg caacacgatg atgaatcgca agaaacatct tcgggttgtg
    15961 aggttaagcg actaagcgta cacggtggat gccctggcag tcagaggcga tgaaggacgt
    16021 gctaatctgc gataagcgtc ggtgaggtga tatgaaccgt tataaccggc gatttccgaa
    16081 tggggaaacc cagtgtgttt cgacacacta tcattaactg aatccatagg ttaatgaggc
    16141 gaaccggggg aactgaaaca tctaagtacc ccgaggaaaa gaaatcaacc gagattcccc
    16201 cagtagcggc gagcgaacgg ggaggagccc agagcctgaa tcagtgtgtg ttagtggaag
    16261 cgtctggaaa ggcgcgcgat acagggtgac agccccgtac acaaaaatgc acatattgtg
    16321 agctcgatga gtagggcggg acacgtggta tcctgtctga atatgggggg accatcctcc
    16381 aaggctaaat actcctgatg accgatagtg aaccagtacc gtgagggaaa ggcgaaaaga
    16441 accccggcga ggggagtgaa aaagaacctg aaaccgtgta cgtacaagca ggggagcctc
    16501 ttaatggggt gactgcgtac cttttgtata atgggtcagc gacttatatt ctgtagcaag
    16561 gttaaccgaa tagggagacg aagggaaacc gagtcttaac tgggcgttaa gttgcagggt
    16621 atagacccga aacccggtga tctagccatg ggcaggttga aggttgggta acactaactg
    16681 gaggaccgaa ccgactaatg ttgaaaaatt agcggatgac ttgtggctgg ggtgaaaggc
    16741 caatcaaacc gggagatagc tggttctccc cgaaagctat ttaggtagcg cctcgtgaat
    16801 tcatctccgg gggtagagca ctgtttcggc aagggggtca tcccgactta ccaacccgat
    16861 gcaaactgcg aataccggag aatgttatca cggagacaca cggcgggtgc taacgtccgt
    16921 cgtgaagagg gaaacaaccc agaccgccag ctaaggatcc aaagtcatgg ttaagtggga
    16981 aacgatgtgg gaaggcccag acagccagga tgttggctta gaagcagcca tcatttaaag
    17041 aaagcgtaat agctcactgg tcgagtcggc ctgcgcggaa gatgtaacgg ggctaaacca
    17101 tgcaccgaag ctgcggcagc gacactatgg ttgttgggta ggggagcgtt ctgtaagcct
    17161 gtgaaggtgg ctgtgagggt tgctggaggt atcagaagtg cgaatgctga cataagtaac
    17221 gataaagcgg tgaaaagccc gctcgccgga agaccaaggg ttcctgtcca acgttaatcg
    17281 ggcagggtga gtcgacccct aaggcgaggc cgaaaggcgt agtcgatggg aaacaggtta
    17341 ataatttcct gtacttggtg ttactgcgaa ggggggacgg agaaggctat gttggccggg
    17401 cgacggttgt ccggtttaag cgtgtaggct ggttttccag gcaaatccgg aaaatcaagg
    17461 ctgaggcgtg atgacgaggc actacggtgc tgaagcgaca aatgccctgc ttccaggaaa
    17521 agcctctaag catcaggtaa catcaaatcg taccccaaac cgacacaggt ggtcagtgta
    17581 gagaatacca aggcgcttga gagaactcgg gtgaaggaac taggcaaaat ggtgccgtaa
    17641 cttcgggaga aggcacgctg atatgtaggt gaagcgactt gctcgtggag ctgaaatcag
    17701 tcgaagatac cagctggctg caactgttta ttaaaaacac agcactgtgc aaacacacga
    17761 aagtggacgt atacggtgtg acgcctgccc ggtgccggaa ggttaattga tggggttagc
    17821 ggtaacgcga agctcttgat cgaagccccg gtaaacggcg gccgtaacta taacggtcct
    17881 aaggtagcga aattccttgt cgggtaagtt ccgacctgca cgaatggcgt aatgatggcc
    17941 aggctgtctc cacccgagac tcagtgaaat tgaactcgct gtgaagatgc agtgtacccg
    18001 cggcaagacg gaaagacccc gtgaaccttt actatagctt gacactgaac attgagcctt
    18061 gatgtgtagg ataggtggag gctttgaagt gtggacgcca gtctgcatgg agccgacctt
    18121 gaaataccac cctttaatgt ttgatgttct aacgtgggcc ccttaccggg gttgcggaca
    18181 gtgtctggtg ggtagtttga ctggggcggt ctcctcctaa agagtaacgg aggagcacga
    18241 aggttggcta atcctggtcg gacatcagga ggttagtgca atggcataag ccagcttgac
    18301 tgcgagcgtg acggcgcgag caggtgcgaa agcaggtcat agtgatccgg tggttctgaa
    18361 tggaagggcc atcgctcaac ggataaaagg tactccggga taacaggctg ataccgccca
    18421 agagttcata tcgacggcgg tgtttggcac ctcgatgtcg gctcatcaca tcctgggctg
    18481 aagtaggtcc caagggtatg gctgttcgcc atttaaagtg gtacgcgagc tgggtttaga
    18541 acgtcgtgag acagttcggt ccctatctgc cgtgggcgct ggagaactga ggggggctgc
    18601 tcctagtacg agaggaccgg agtggacgca tcactggtgt tcgggttgtc atgccaatgg
    18661 cactgcccgg tagctaaatg cggaagagat aagtgctgaa agcatctaag cacgaaactt
    18721 gccccgagat gagttctccc tgactccttg agagtcctga aggaacgttg aagacgacga
    18781 cgttgatagg ccgggtgtgt aagcgcagcg atgcgttgag ctaaccggta ctaatgaacc
    18841 gtgaggctta accttacaac gccgaagatg ttttggcgga agagacatcg ataagtaagc
    18901 ttgatagcag attaaatcga cagtcataac gggacgtgtt gataaaacag aatttgcctg
    18961 gcggccttag cgcggtggtc cacctgaccc catgccgaac tcagaagtga acgccgtagc
    19021 gccgatggta gtgtggggtc tccccatgca gagtagggaa ctgccaggta tcaaattaaa
    19081 gcagtaagcc ggtcataaaa ccggtggttg taaaagaatt cggtggagcg gtagttcagt
    19141 cggttagaat acctgcctgt cacgcagggg ggcgcgggtt cgagtcccgt ccgttccgcc
    19201 acttactaag aagcctcgag ttaacgctcg aggttttttt ttcgtttgta tttctattat
    19261 tgccaaaatc gcaaaaatcc tctgcgtttt tacgccattt ttccgcaaca gtctgaagcc
    19321 catatcacct cagttaacga aaatagcata aaagaggcat attatggcta tcctgcattt
    19381 gtgtgttagg cactttccgt ctgaaagacg acgttgttat ttcatctgtg aaaacggcgc
    19441 ttgaacttga ttatcgcgca attgataacg cacaatctat gataacgaag ccgcagtagg
    19501 tcaggcgatt gcagaaagtg gcgtgccacg tcatgaactc cacatcacca ctaaaatctg
    19561 gattgaaatc tcagcaaaga caaattgatc ccgagtctga aagagagcct gcaaaaattg
    19621 cgtaccgatt atgttgatct gacgctaatc cactggccgt caccaaacga tgaagtctct
    19681 gttgaagagt ttatgcaggc gctgctggaa gccaaaaaac aaggctgacg cgtgagatcg
    19741 gtatttccaa ctttacgatc ccattgatgg aaaagcgatt gctgctgttg gcgctgaaaa
    19801 catcgctact aaccagattg aactctctcc ttatctgcaa aaccgtaaag tggtcgcttg
    19861 ggcaaacagc acagtatcca tattacttcc tatatgacgc tggcgtatgg caaggcactg
    19921 aaagatgagg ttattgctcg tatgcagcta aacacaatgc gactccggct caaggtgatt
    19981 ctggcgtggg ctatggggga aggttactca gtaattcctt cttctactaa acgtgaaaac
    20041 ctgagagtaa tcttaaggcc acaaaattta cagcttgatg ccgaagataa aaaagcgatc
    20101 gccgcactgg atttgcaacg accgcctggt tagcccggaa ggtctggctc ctgaatggga
    20161 ttaagcctct ctgacagctc ctccgggagc tgtttttaca tgctcgctaa ggaaatcgat
    20221 aaaagcccgg atgcgcgtac ttaccgcacg gtcgctgtaa taactgcact gatatggcat
    20281 ttctactggc aacactttat ctgctattaa ctccaccaat tctccgcgag cgatttcttt
    20341 gtcgatcatg tagtcggaca aacacgcaat cccgttgcac tcaggcaaag ctgtttcagt
    20401 gtttccccac tattggatga caaaccgtac ttaacctcat gtaattgtcc atcgctacag
    20461 gctatcggcc aggtattgag gaagcgggtt cagtgatccc aggcaaatat gttgctttaa
    20521 atcgtcgatc gtttctggct tcccgtagcg ggaaatataa tcgggggagg cgataatttt
    20581 tcgataactg ttaaatagcg gcctggcacg taagctgaat ccgttaacgt accggcgcgt
    20641 atcgcgacat ccactttttt tcgatcaaat taataatcgt ttcggaggag actagcgata
    20701 aagtgacttc cggatagcgt tcacgaaaag gcttaatcaa cggcatcaga aagtgcagca
    20761 ccactggagt tgcggcatcg atccgtaaca gtccacgcgg tgtattacgc gtctccataa
    20821 tttctgattc tgccgctgcc atctcctgca aaattgactg tacgcgacga aaataacgct
    20881 cgccttcttc cgtcaggcta agttgccgcg tggtccgatt aagcaaggct aacgccaagt
    20941 tttcatctcc agctttttca ccgcccggct taccgctgag tttgcttgcc ctaattgttc
    21001 cgctgcccgg ctaaagctgc cgctttcacg actgaaacaa aaatggcgag tttcttcgac
    21061 gtggctttca tttttgctcc tgttgcaata gaagagatat tttgaattta tttgtcatta
    21121 aaccatcagg atgcgagata tgccatccga tttaatgttc tcataatgag caaatcctga
    21181 ccggtgtaag cacttgctta catacaatat acaattgctc gttgaagagt gagctaaatc
    21241 cctataacag tagaaccctc ccgagtgcgg aagggttgac gtgatagagg tttcaaagtc
    21301 aaaagtgcga aaaaacacct atgccatgcg ctatgttgcc ggacaacctg cggaaaggat
    21361 cttaccgccg gggtcttttg cgagcatcgg ccaggcatta ccacctggag aaccgttaag
    21421 taccgaagcg tattcggatc ctggtgtgga acatatacaa acagcaacgc gctgaatggt
    21481 tgtcgtgtta aagaactacg gcaaagatgc acatctggtg ttattgcagg aagcgcagac
    21541 aacgccagag ttagtacagg ttttgcgact gctaactatc ttgccgccga tcaggtaccg
    21601 cgctttcgtg ctgccacaac atccttctgg cgtaatgacc ctttcggcgg cacatccagt
    21661 gtattgctgc ccgttacgtg aacgagaacc cattttgcgt ctggcgaagt cggcactggt
    21721 gacggtctat ccgttacctg acacccgcct gtttgatggt ggttaatata cacgccgtca
    21781 acttcagtct gggcgtggat gtctatagta acagttactt cctattggcg atcagatagc
    21841 tcccacagtg tcccggtcat tatggcggga gatttcaatg cctggagccg tagaaggatg
    21901 aacgcgttat atcgtgcttg cgcgggaaat gtcgctgcgc caggtgcgtt tttaccgatg
    21961 atcgagcgcc gtcgggcgtt tggtcgcccg ctcgattttg ttttctaccg tggtctgaac
    22021 gtcagcgag
//
