LOCUS       CP082555                9473 bp    DNA     circular BCT 13-JAN-2022
DEFINITION  Salmonella enterica subsp. enterica serovar Schwarzengrund strain
            CVM N18S1602 plasmid pN18S1602-2, complete sequence.
ACCESSION   CP082555
VERSION     CP082555.1
DBLINK      BioProject: PRJNA292661
            BioSample: SAMN12360201
KEYWORDS    .
SOURCE      Salmonella enterica subsp. enterica serovar Schwarzengrund
  ORGANISM  Salmonella enterica subsp. enterica serovar Schwarzengrund
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9473)
  AUTHORS   Li,C., Tyson,G.H., Hsu,C.H., Harrison,L., Strain,E., Tran,T.T.,
            Tillman,G.E., Dessai,U., McDermott,P.F. and Zhao,S.
  TITLE     Long-Read Sequencing Reveals Evolution and Acquisition of
            Antimicrobial Resistance and Virulence Genes in Salmonella enterica
  JOURNAL   Front Microbiol 12, 777817 (2021)
   PUBMED   34867920
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9473)
  CONSRTM   NARMS: The National Antimicrobial Resistance Monitoring System
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2019) Center for Veterinary Medicine, US Food and
            Drug Administration, 8401 Muirkirk Rd, Laurel, MD, USA
REFERENCE   3  (bases 1 to 9473)
  AUTHORS   Li,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2021) CVM/OR, FDA-CVM, 8401 Muirkirk Rd, MOD2,
            Laurel, MD 20708, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JUN-2020
            Assembly Method :: SMRTLink Microbial Assembly v. SMRTLink9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 367x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 08/30/2021 17:10:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 4,630
            CDSs (total)                      :: 4,510
            Genes (coding)                    :: 4,414
            CDSs (with protein)               :: 4,414
            Genes (RNA)                       :: 120
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 14
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 49 of 96
            Pseudo Genes (incomplete)         :: 52 of 96
            Pseudo Genes (internal stop)      :: 18 of 96
            Pseudo Genes (multiple problems)  :: 21 of 96
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..9473
                     /organism="Salmonella enterica subsp. enterica serovar
                     Schwarzengrund"
                     /mol_type="genomic DNA"
                     /strain="CVM N18S1602"
                     /serovar="Schwarzengrund"
                     /isolation_source="ground turkey"
                     /sub_species="enterica"
                     /db_xref="taxon:340190"
                     /plasmid="pN18S1602-2"
                     /geo_loc_name="USA:TN"
                     /collection_date="2018"
                     /collected_by="FDA"
     gene            complement(join(8429..9473,1..1085))
                     /locus_tag="FQD73_022665"
     CDS             complement(join(8429..9473,1..1085))
                     /locus_tag="FQD73_022665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001395566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="UAI38442.1"
                     /translation="MAIYHLTAKTGSRSGGQSARAKADYIQREGKYARDMDEVLHAESG
                     HMPEFVERPADYWDAADLYERANGRLFKEVEFALPVELTLDQQKALASEFAQHLTGAER
                     LPYTLAIHAGGGENPHCHLMISERINDGIERPAAQWFKRYNGKTPEKGGAQKTEALKPK
                     AWLEQTREAWADHANRALERAGHDARIDHRTLEAQGIERLPGVHLGPNVVEMEGRGIRT
                     DRADVALNIDTANAQIIDLQEYREAIDHERNRQSEEIQRHQRVSGADRTAGPEHGDTGR
                     RSPAGHEPDPAGQRGAGGGVAESPAPDRGGMGGAGQRVAGGSRRGEQRRAERPERVAGV
                     ALEAMANRDAGFHDAYGGAADRIVALARPDATDNRGRLDLAALGGPMKNDRTLQAIGRQ
                     LKAMGCERFDIGVRDATTGQMMNREWSAAEVLQNTPWLKRMNAQGNDVYIRPAEQERHG
                     LVLVDDLSEFDLDDMKAEGREPALVVETSPKNYQAWVKVADAAGGELRGQIARTLASEY
                     DADPASADSRHYGRLAGFTNRKDKHTTRAGYQPWVLLRESKGKTATAGPALVQQAGQQI
                     EQAQRQQEKARRLASLELPERQLSRHRRTALDEYRSEMAGLVKRFGDDLSKCDFIAAQK
                     LASRGRSAEEIGKAMAEASPALAERKPGHEADYIERTVSKVMGLPSVQLARAELARAPA
                     PRQRGMDRGGPDFSM"
                     /name="MobA/MobL family protein"
     gene            1284..1568
                     /locus_tag="FQD73_022670"
     CDS             1284..1568
                     /locus_tag="FQD73_022670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein C"
                     /protein_id="UAI38443.1"
                     /translation="MVKGSNKAADRLAKLEEQRARINAEIQRVRAREQQQERKNETRRK
                     VLVGAMILAKVNSSEWPEDRLMAAMDAYLERDHDRALFGLPPRQKDEPG"
                     /name="mobilization protein C"
     gene            2156..2230
                     /locus_tag="FQD73_022675"
                     /pseudo=""
     CDS             2156..2230
                     /locus_tag="FQD73_022675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058717.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /name="EamA family transporter"
     gene            complement(2262..3461)
                     /gene="tet(A)"
                     /locus_tag="FQD73_022680"
     ARG             complement(2266..3461)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3567..4193
                     /gene="tetR(A)"
                     /locus_tag="FQD73_022685"
     CDS             3567..4193
                     /gene="tetR(A)"
                     /locus_tag="FQD73_022685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="UAI38445.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGGTVEQAPLSPLL
                     RAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            complement(4361..5056)
                     /locus_tag="FQD73_022690"
                     /pseudo=""
     CDS             complement(4361..5056)
                     /locus_tag="FQD73_022690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="APH(3'') family aminoglycoside
                     O-phosphotransferase"
                     /name="APH(3'') family aminoglycoside O-phosphotransferase"
     gene            complement(5117..5932)
                     /gene="sul2"
                     /locus_tag="FQD73_022695"
     ARG             complement(5121..5932)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(6241..7092)
                     /locus_tag="FQD73_022700"
     CDS             complement(6241..7092)
                     /locus_tag="FQD73_022700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="UAI38438.1"
                     /translation="MVKPKNKHSLSHVRHDPAHCLAPGLFRALKRGERKRSKLDVTYDY
                     GDGKRIEFSGPEPLGADDLRILQGLVAMAGPNGLVLGPEPKTEGGRQLRLFLEPKWEAV
                     TADAMVVKGSYRALAKEIGAEVDSGGALKHIQDCIERLWKVSIIAQNGRKRQGFRLLSE
                     YASDEADGRLYVALNPLIAQAVMGGGQHVRISMDEVRALDSETARLLHQRLCGWIDPGK
                     TGKASIDTLCGYVWPSEASGSTMRKRRQRVREALPELVALGWTVTEFAAGKYDITRPKA
                     AG"
                     /name="replication protein"
     gene            complement(7079..7918)
                     /locus_tag="FQD73_022705"
     CDS             complement(7079..7918)
                     /locus_tag="FQD73_022705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="UAI38439.1"
                     /translation="MATHKPINILEAFAAAPPPLDYVLPNMVAGTVGALVSPGGAGKSM
                     LALQLAAQIAGGPDLLEVGELPTGPVIYLPAEDPPTAIHHRLHALGAHLSAEERQAVAD
                     GLLIQPLIGSLPNIMAPEWFDGLKRAAEGRRLMVLDTLRRFHIEEENASGPMAQVIGRM
                     EAIAADTGCSIVFLHHASKGAAMMGAGDQQQASRGSSVLVDNIRWQSYLSSMTSAEAEE
                     WGVDDDQRRFFVRFGVSKANYGAPFADRWFRRHDGGVLKPAVLERQRKSKGVPRGEA"
                     /name="helicase RepA family protein"
     gene            complement(7948..8154)
                     /locus_tag="FQD73_022710"
     CDS             complement(7948..8154)
                     /locus_tag="FQD73_022710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007857788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UAI38440.1"
                     /translation="MKDQKDKQTGDLLASPDAVRQARYAERMKAKGMRQRKFWLTDDEY
                     EALRECLEELRAAQGGGSDPASA"
                     /name="hypothetical protein"
     gene            complement(8156..8368)
                     /locus_tag="FQD73_022715"
     CDS             complement(8156..8368)
                     /locus_tag="FQD73_022715"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UAI38441.1"
                     /translation="MEYEKSASGSVYLIKSDKGYWLPGGFGYTSNKAEAGRFSVADMAS
                     LNLDGCTLSLFREDKPFGPGKFLGD"
                     /name="hypothetical protein"
     ARG             complement(4332..5056)
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.07"
                     /coverage="90.26"
     Typing          complement(1175..1330)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.28e-76"
     Typing          complement(7080..7901)
                     /name="IncQ1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="96.0"
                     /evalue="0.0"
     Typing          complement(4..1085)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          complement(8433..9472)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 cgatcagcag caccaccgta ggcatcatgg aagccagcat cacggttagc catagcttcc
       61 agtgccaccc ccgcgacgcg ctccgggcgc tctgcgcggc gctgctcacc tcggcggcta
      121 cctcccgcaa ctctttggcc agctccaccc atgccgcccc tgtctggcgc tgggctttca
      181 gccactccgc cgcctgcgcc tcgctggcct gctgggtctg gctcatgacc tgccgggctt
      241 cgtcggccag tgtcgccatg ctctgggcca gcggttcgat ctgctccgct aactcgttga
      301 tgcctctgga tttcttcact ctgtcgattg cgttcatggt ctattgcctc ccggtattcc
      361 tgtaagtcga tgatctgggc gttggcggtg tcgatgttca gggccacgtc tgcccggtcg
      421 gtgcggatgc cccggccttc catctccacc acgttcggcc ccaggtgaac accgggcagg
      481 cgctcgatgc cctgcgcctc aagtgttctg tggtcaatgc gggcgtcgtg gccagcccgc
      541 tctaatgccc ggttggcatg gtcggcccat gcctcgcggg tctgctcaag ccatgccttg
      601 ggcttgagcg cttcggtctt ctgtgccccg cccttctccg gggtcttgcc gttgtaccgc
      661 ttgaaccact gagcggcggg ccgctcgatg ccgtcattga tccgctcgga gatcatcagg
      721 tggcagtgcg ggttctcgcc gccaccggca tggatggcca gcgtatacgg caggcgctcg
      781 gcaccggtca ggtgctgggc gaactcggac gccagcgcct tctgctggtc gagggtcagc
      841 tcgaccggca gggcaaattc gacctccttg aacagccgcc cattggcgcg ttcatacagg
      901 tcggcagcat cccagtagtc ggcgggccgc tcgacgaact ccggcatgtg cccggattcg
      961 gcgtgcaaga cttcatccat gtcgcgggca tacttgcctt cgcgctggat gtagtcggcc
     1021 ttggccctgg ccgattggcc gcccgacctg ctgccggttt tcgccgtaag gtgataaatc
     1081 gccatgctgc ctcgctgttg cttttgcttt tcggctccat gcaatggccc tcggagagcg
     1141 caccgcccga agggtggccg ttaggccagt ttctcgaaga gaaaccggta agtgcgccct
     1201 cccctacaaa gtagggtcgg gattgccgcc gctgtgcctc catgatagcc tacgagacag
     1261 cacattaaca atggggtgtc aagatggtta aggggagcaa caaggcggcg gatcggctgg
     1321 ccaagctcga agaacaacga gcgcgaatca atgccgaaat tcagcgggtg cgggcaaggg
     1381 aacagcagca agagcgcaag aacgaaacaa ggcgcaaggt gctggtgggg gccatgattt
     1441 tggccaaggt gaacagcagc gagtggccgg aggatcggct catggcggca atggatgcgt
     1501 accttgaacg cgaccacgac cgcgccttgt tcggtctgcc gccacgccag aaggatgagc
     1561 cgggctgaat gatcgaccga gacaggccct gcggggctgc acacgcgccc ccacccttcg
     1621 ggtaggggga aaggccgcta aagcggctaa aagcgctcca gcgtatttct gcggggtttg
     1681 gtgtggggtt tagcgggctt tgcccgcctt tccccctgcc gcgcagcggt ggggcggtgt
     1741 gtagcctagc gcagcgaata gaccagctat ccggcctctg gccgggcata ttgggcaagg
     1801 gcagcagcgc cccacaaggg cgctgataac cgcgcctagt ggattattct tagataatca
     1861 tggatggatt tttccaacac cccgccagcc cccgcccctg ctgggtttgc aggtttgggg
     1921 gcgtgacagt tattgcaggg gttcgtgaca gttattgcag gggggcgtga cagttattgc
     1981 aggggttcgt gacagttagt acgggagtga cgggcactgg ctggcaatgt ctagcaacgg
     2041 caggcatttc ggctgagggt aaaagaactt tccgctaagc gatagactgt atgtaaacac
     2101 agtattgcaa ggacgcggaa catgcctcat gtggcggcca ggacggccag ccgggatcgg
     2161 gagtatctgg ctgggccaac gttccaaccg cactcctagg gcgcgtatag cttgccggaa
     2221 gtcgccttga cccgcatggc ataggcctat cgtttccacg atcagcgatc ggctcgttgc
     2281 cctgcgccgc tccaaagccc gcgacgcagc gccggcaggc agagcaagta gagggcagcg
     2341 cctgcaatcc atgcccaccc gttccacgtt gttatagaag ccgcatagat cgccgtgaag
     2401 aggaggggtc cgacgatcga ggtcaggctg gtgagcgccg ccagtgagcc ttgcagctgc
     2461 ccctgacgtt cctcatccac ctgcctggac aacattgctt gcagcgccgg cattccgatg
     2521 ccacccgaag caagcaggac catgatcggg aacgccatcc atccccgtgt cgcgaaggca
     2581 agcaggatgt agcctgtgcc gtcggcaatc attccgagca tgagtgcccg cctttcgccg
     2641 agccgggcgg ctacagggcc ggtgatcatt gcctgggcga gtgaatgcag aatgccaaat
     2701 gcggcaagcg aaatgccgat cgtggtcgcg tcccagtgaa agcgatcctc gccgaaaatg
     2761 acccaaagcg cggccggcac ctgtccgaca agttgcatga tgaagaagac cgccatcagg
     2821 gcggcgacga cggtcatgcc ccgggcccac cggaacgaag cgagcgggtt gagagcctcc
     2881 cggcgtaacg gccggcgttc gcctttgtgc gactccggca aaaggaaaca gcccgtcagg
     2941 aaattgaggc cgttcaaggc tgccgcggcg aagaacggag cgtgggggga gaaaccgccc
     3001 atcagcccac cgagcacagg tcccgcgacc atcccgaacc cgaaacaggc gctcatgaag
     3061 ccgaagtgcc gcgcgcgctc atcgccatca gtgatatcgg caatataagc gccggctacc
     3121 gccccagtcg ccccggtgat gccggccacg atccgcccga tatagagaac ccaaaggaaa
     3181 ggcgccgtcg ccatgatggc gtagtcgaca gcagcgccgg ccagcgagac gagcaagacc
     3241 ggccgccgcc cgaaacgatc cgacagcgcg cccagcacag gtgcgcaggc aaattgcatc
     3301 aacgcataca gcgccagcag aatgccatag tgggcggtga cgtcgttcga gtgaaccaga
     3361 tcgcgcagga ggcccggcag caccggcata atcaggccga tgccgacagc gtcgagcgcg
     3421 acagtgctca gaattacgat caggggtctg ttgggtttca cgtctggcct ccggaccagc
     3481 ctccgctggt ccgattgaac gcgcggattc tttatcactg ataagttggt ggacatatta
     3541 tgtttatcag tgataaagtg tcaagcatga caaagttgca gccgaataca gtgatccgtg
     3601 ccgccctgga cctgttgaac gaggtcggcg tagacggtct gacgacacgc aaactggcgg
     3661 aacggttggg ggttcagcag ccggcgcttt actggcactt caggaacaag cgggcgctgc
     3721 tcgacgcact ggccgaagcc atgctggcgg agaatcatac gcattcggtg ccgagagccg
     3781 acgacgactg gcgctcattt ctgatcggga atgcccgcag cttcaggcag gcgctgctcg
     3841 cctaccgcga tggcgcgcgc atccatgccg gcacgcgacc gggcgcaccg cagatggaaa
     3901 cggccgacgc gcagcttcgc ttcctctgcg aggcgggttt ttcggccggg gacgccgtca
     3961 atgcgctgat gacaatcagc tacttcactg ttggggccgt gcttgaggag caggccggcg
     4021 gcaccgttga acaggctccg ctctcgccgc tgttgcgggc cgcgatagac gccttcgacg
     4081 aagccggtcc ggacgcagcg ttcgagcagg gactcgcggt gattgtcgat ggattggcga
     4141 aaaggaggct cgttgtcagg aacgttgaag gaccgagaaa gggtgacgat tgatcaggac
     4201 cgctgccgga gcgcaaccca ctcactacag cagagccatg tagacaacat cccctccccc
     4261 tttccaccgc gtcagacgcc cgtagcagcc cgctacgggc tttttcatgc cctgccctag
     4321 cgtccaagcc tcacggccgc gctcggcctc tctggcggcc ttctggcgct gcccagttct
     4381 cttcggcgtt agcaatcatg agtgccaaat cggcatagcg atctgctgtt ccgagccgcc
     4441 caaggtcgat cagacccgtg cattgaagag ttttagggtc caccatgaag ttcggcatgc
     4501 agggatcacc atggcaaaca accatatcgg tgcgctcttg gtcgagccgc accggtagct
     4561 ctcgttcgac acgagccaaa agatcgagct gcggcgtact cttgtcctcg tccggtaaga
     4621 agtcgggatt gacggcattg cgggacacca catcaacggc gcgtccgaac attcgcgaca
     4681 gcctgcgctc aaacggacat tgatcaaccg ataggctgtg aacagcgcca agttgctgcc
     4741 ccattgacgg ccacgctttg agcaaatccg ctccagacag atcagccgcc ggtactcccg
     4801 gaattgccgt tatcaccaag catgcaccct cctgttcctc ctgccagttg atgacctcgg
     4861 ggcaagccac acctcgacct ttgagccaaa tgaggcggtc acgctctcca gcgagctcac
     4921 cgcggcggga agcaggtgcg attttcgcga aggcatgccc gtcaccacgt cgaaaaacaa
     4981 aatcaccaga ttctccgcct ctgacaggca accagtcaga atgcgattca ccaaaaaaaa
     5041 tattagttcg attcaatgga ggttccttca gttttctgat gaagcgcgaa tatagagaaa
     5101 tatcccgaat gtgcagttaa cgaattcttg cggtttcttt cagcgccgcc aataccgcca
     5161 gcccgtcgcg caaggggcgc ggctcgtgtg tgcggatgaa gtcagctcca cctgcggcgg
     5221 cggcaagctc tgcagcgagt gtcgcggccc cgacatcccc cggaccacgg cctgtgagcg
     5281 cgcgcagaaa ggatttgcgc gaaacagaca gaagcaccgg caaatcgaag cgcagccgca
     5341 attcatcgaa ccgcgccagc accgagagcg aggtttcggg agcagccccc agaaaaaacc
     5401 ccatgccggg atcaaggaca aggcggttgc gtttgatacc ggcacccgtc agcgccgcga
     5461 tgcgcgcgtc aaagaacgcc gcaatgtgat ccatgatgtc gccagcgggt gcctcgcgcc
     5521 gatctgcctg cccgtcttgc accgaatgca taacgacgag tttggcagat gatttcgcca
     5581 attgcggata gaacgcagcg tctggaaaac cgcgaatatc attgagatag gccacaccac
     5641 gcgacaaggc ataggcttgc gtcgcgggtt gataactgtc gagcgagacg ggaatgccat
     5701 ctgccttgag cgcgtccagc accggcgcga tacgctcgat ttctgtgtcg gacgaaacag
     5761 gcgcggcgtc ggggttgctg gatgccggac cgaggtcgat cacatctgcc ccctcggcca
     5821 tcagcttacg cgcctgcgca atggctgcgt ctggcgccag ataccggcct ccatcggaga
     5881 aactgtccga ggttatgttg acgatgccga aaatgatgag cgatttattc atgggggctt
     5941 ctataataat aataatcgag catgagtctc atacggatgc tcgggtcgaa agggaatccc
     6001 caggcgagta acctgtttgc ggtgatccat tagctgcagg agcagaagag catacatctg
     6061 gaagcaaagc caggaaagcg gcctatggag ctgtgcggca gcgctcagta ggcaattttt
     6121 caaaatattg ttaagccttt tctgagcatg gtatttttca tggtattacc aattagcagg
     6181 aaaataagcc attgaatata aaagataaaa atgtcttgtt tacaatagag tggggggggg
     6241 tcagcctgcc gccttgggcc gggtgatgtc gtacttgccc gccgcgaact cggttaccgt
     6301 ccagcccagc gcgaccagct ccggcaacgc ctcgcgcacc cgctggcggc gcttgcgcat
     6361 ggtcgaacca ctggcctctg acggccagac atagccgcac aaggtatcta tggaagcctt
     6421 gccggttttg ccggggtcga tccagccaca cagccgctgg tgcagcaggc gggcggtttc
     6481 gctgtccagc gcccgcacct cgtccatgct gatgcgcaca tgctggccgc cacccatgac
     6541 ggcctgcgcg atcaaggggt tcagggccac gtacaggcgc ccgtccgcct cgtcgctggc
     6601 gtactccgac agcagccgaa acccctgccg cttgcggcca ttctgggcga tgatggatac
     6661 cttccaaagg cgctcgatgc agtcctgtat gtgcttgagc gccccaccac tatcgacctc
     6721 tgccccgatt tcctttgcca gcgcccgata gctacctttg accaccatgg catcagcggt
     6781 gacggcctcc cacttgggtt ccaggaacag ccggagctgc cgtccgcctt cggtcttggg
     6841 ttccgggcca agcactaggc cattaggccc agccatggcc accagccctt gcaggatgcg
     6901 cagatcatca gcgcccagcg gctccgggcc gctgaactcg atccgcttgc cgtcgccgta
     6961 gtcatacgtc acgtccagct tgctgcgctt gcgctcgccc cgcttgaggg cacggaacag
     7021 gccgggggcc agacagtgcg ccgggtcgtg ccggacgtgg ctgaggctgt gcttgttctt
     7081 aggcttcacc acggggcacc cccttgctct tgcgctgcct ctccagcacg gcgggcttga
     7141 gcaccccgcc gtcatgccgc ctgaaccacc gatcagcgaa cggtgcgcca tagttggcct
     7201 tgctcacacc gaagcggacg aagaaccggc gctggtcgtc gtccacaccc cattcctcgg
     7261 cctcggcgct ggtcatgctc gacaggtagg actgccagcg gatgttatcg accagtaccg
     7321 agctgccccg gctggcctgc tgctggtcgc ctgcgcccat catggccgcg cccttgctgg
     7381 catggtgcag gaacacgata gagcacccgg tatcggcggc gatggcctcc atgcgaccga
     7441 tgacctgggc catggggccg ctggcgtttt cttcctcgat gtggaaccgg cgcagcgtgt
     7501 ccagcaccat caggcggcgg ccctcggcgg cgcgcttgag gccgtcgaac cactccgggg
     7561 ccatgatgtt gggcaggctg ccgatcagcg gctggatcag caggccgtca gccacggctt
     7621 gccgttcctc ggcgctgagg tgcgccccaa gggcgtgcag gcggtgatga atggcggtgg
     7681 gcgggtcttc ggcgggcagg tagatcaccg ggccggtggg cagttcgccc acctccagca
     7741 gatccggccc gcctgcaatc tgtgcggcca gttgcagggc cagcatggat ttaccggcac
     7801 caccgggcga caccagcgcc ccgaccgtac cggccaccat gttgggcaaa acgtagtcca
     7861 gcggtggcgg cgctgctgcg aacgcctcca gaatattgat aggcttatgg gtagccattg
     7921 attgcctcct ttgcaggcag ttggtggtta ggcgctggcg gggtcactac ccccgccctg
     7981 cgccgctctg agttcttcca ggcactcgcg cagcgcctcg tattcgtcgt cggtcagcca
     8041 gaacttgcgc tgacgcatcc ctttggcctt catgcgctcg gcatatcgcg cttggcgtac
     8101 agcgtcaggg ctggccagca ggtcgccggt ctgcttgtcc ttttggtctt tcatatcagt
     8161 caccgagaaa cttgccgggg ccgaaaggct tgtcttcgcg gaacaaggac aaggtgcagc
     8221 cgtcaaggtt aaggctggcc atatcagcga ctgaaaagcg gccagcctcg gccttgtttg
     8281 acgtataacc aaagccaccg ggcaaccaat agcccttgtc acttttgatc aggtagaccg
     8341 accctgaagc gcttttttcg tattccataa aacccccttc tgtgcgtgag tactcatagt
     8401 ataacaggcg tgagtaccaa cgcaagcact acatgctgaa atctggcccg cccctgtcca
     8461 tgcctcgctg gcggggtgcc ggtgcccgtg ccagctcggc ccgcgcaagc tggacgctgg
     8521 gcagacccat gaccttgctg acggtgcgct cgatgtaatc cgcttcgtgg ccgggcttgc
     8581 gctctgccag cgctgggctg gcctcggcca tggccttgcc gatttcctcg gcactgcggc
     8641 cccggctggc cagcttctgc gcggcgataa agtcgcactt gctgaggtca tcaccgaagc
     8701 gcttgaccag cccggccatc tcgctgcggt actcgtccag cgccgtgcgc cggtggcggc
     8761 taagctgccg ctcgggcagt tcgaggctgg ccagcctgcg ggccttctcc tgctgccgct
     8821 gggcctgctc gatctgctgg ccagcctgct gcaccagcgc cgggccagcg gtggcggtct
     8881 tgcccttgga ttcacgcagc agcacccacg gctgataacc ggcgcgggtg gtgtgcttgt
     8941 ccttgcggtt ggtgaagccc gccaagcggc catagtggcg gctgtcggcg ctggccgggt
     9001 cggcgtcgta ctcgctggcc agcgtccggg caatctgccc ccgaagttca ccgcctgcgg
     9061 cgtcggccac cttgacccat gcctgatagt tcttcgggct ggtttccact accagggcag
     9121 gctcccggcc ctcggctttc atgtcatcca ggtcaaactc gctgaggtcg tccaccagca
     9181 ccagaccatg ccgctcctgc tcggcgggcc tgatatacac gtcattgccc tgggcattca
     9241 tccgcttgag ccatggcgtg ttctggagca cttcggcggc tgaccattcc cggttcatca
     9301 tctggccggt ggtggcgtcc ctgacgccga tatcgaagcg ctcacagccc atggccttga
     9361 gctgtcggcc tatggcctgc aaagtcctgt cgttcttcat cgggccacca agcgcagcca
     9421 gatcgagccg tcctcggttg tcagtggcgt caggtcgagc aagagcaacg atg
//
