LOCUS       CP067925               28729 bp    DNA     circular BCT 02-MAR-2022
DEFINITION  Klebsiella pneumoniae strain ARLG-3188 plasmid pC242_3, complete
            sequence.
ACCESSION   CP067925
VERSION     CP067925.1
DBLINK      BioProject: PRJNA658369
            BioSample: SAMN15868961
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 28729)
  AUTHORS   Shropshire,W.C.
  TITLE     Highly Conserved and Distinct Accessory Genomes Drive Independent
            and Parallel Endemic Spread of Carbapenem-Resistant Klebsiella
            pneumoniae Clonal Groups 258 and 307
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28729)
  AUTHORS   Shropshire,W.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) HMH-CDI, Hackensack-Meridian Health Center
            for Discovery and Innovation, 340 Kingsland Street, Building 102,
            Nutley, NJ 07110, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Flye v. 2.7
            Assembly Name                     :: C242
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 357x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 01/11/2021 17:42:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.0
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,463
            CDSs (total)                      :: 5,340
            Genes (coding)                    :: 5,238
            CDSs (with protein)               :: 5,238
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 42 of 102
            Pseudo Genes (incomplete)         :: 51 of 102
            Pseudo Genes (internal stop)      :: 20 of 102
            Pseudo Genes (multiple problems)  :: 11 of 102
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..28729
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ARLG-3188"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pC242_3"
                     /geo_loc_name="USA: South"
                     /collection_date="2016"
                     /collected_by="MDRO network"
     gene            join(28586..28729,1..723)
                     /locus_tag="JJ438_27105"
     CDS             join(28586..28729,1..723)
                     /locus_tag="JJ438_27105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="UMJ74195.1"
                     /translation="MGKRSSSVLNYPLVDKVQIFPVDKYRDSLQFLFSLSLWVGKNLPI
                     GIEMDTQALLPATKTFKKRASIKQSNELTEAAYYLPLQAKRVLWLCLMQAYFNDSQEDD
                     SDVLPLFKISVSDYVKYFNVATSVASRDVKAGVNALGESTVTFYPKEGEFEEVKRPWLA
                     EAGMKRGRGSWQIEFNYKVMPFLVGLTSQFTTYSLYDCGQLNSVRVIRLYESLCQFRST
                     GVWITTHDWLCERFMLPASQKNNIAEMKRTFLEPALKKINEKTPLKVTYTTEEDGRLLF
                     NFLDKKQ"
                     /name="replication initiation protein"
     gene            complement(1080..1349)
                     /locus_tag="JJ438_27110"
     CDS             complement(1080..1349)
                     /locus_tag="JJ438_27110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74196.1"
                     /translation="MDAPDYGKQVNFADGPDYGKQVNFTGGRECGEQVNFADGPDYGKQ
                     VNFAGGRDCGKQVNFADGPDCGKQVNFAGGRECGEQVNFADGPD"
                     /name="hypothetical protein"
     gene            1764..2969
                     /locus_tag="JJ438_27115"
     CDS             1764..2969
                     /locus_tag="JJ438_27115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="UMJ74197.1"
                     /translation="MDNIEQLRKVATRAGKLLTSLSESIRQQKEELKLTEFYQEYSKAA
                     LYKLPKLSKGSVEYAVSEMEAGGYIFKKKPSGNTMKYAMTIQNVIDLYNHRKVPKYRDR
                     FDKAFTIFVCNLKGGGSKTVSTASLSHAFRAHPQLLFEDLRILAIDFDPQASLTMFLSH
                     ENSVGLVENTAAQAMLQNVSREELLSDFIVPSIIPGVDVIPASIDDAFLAEGWKGLCEE
                     HLPGKNIHAVLKENIIDKLQHDYDFIFLDSGPHLDAFLKNCIGAADLMLTPLPPATVDF
                     HSSLKFVASLPALIDSIEMDGHTCNLIGNVGFMSKILNKSDHKICHSQAKEVFGADMLD
                     MVLPRLDGFERCGETFDTVISANPATYDGSTEALKSAKSAAEDFAKAVFDRIEFIRTNG
                     GM"
                     /name="AAA family ATPase"
     gene            2969..3943
                     /locus_tag="JJ438_27120"
     CDS             2969..3943
                     /locus_tag="JJ438_27120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="UMJ74198.1"
                     /translation="MSNEKRKTIGRQLNTQASILEMADTGRSQVFTLKTGRKVTFRFVR
                     VPASEVESKTFVNQENNGRDQLALTRESLKSIIQTIKFQQFFPCIGIKQSERIEILDGS
                     RRRASAIFVRTGLDVMVTEEHLSADEARQLAKDIQTAKEHNLREIGLRLIALKESGFNQ
                     KEIAELEGLSQAKVTRALQAAAVPQDLISLFPVQSELSFSDYKLLLEVNEKLGEKGLTP
                     EELIQSVSAQLDAILSDGERPEDEQKASILKLISQASQALIDPSPKEKSVVSPLWSFEE
                     KDKFARKRVKGRTLTYEFSRMSKVIQDELDKAINEVLDRNLSQ"
                     /name="ParB/RepB/Spo0J family partition protein"
     gene            complement(4025..5296)
                     /locus_tag="JJ438_27125"
     CDS             complement(4025..5296)
                     /locus_tag="JJ438_27125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UMJ74199.1"
                     /translation="MFALADVNSFYASCERVFRPDLKGKPIVVLSNNDGNVIARSAEAK
                     PWIKMGTPWFQIKNERYPEKIYAFSSNYELYASISARVMNCLEELAPRVEQYSIDEMFL
                     DLTGVEHCMGLEDFARQLRQQVYDCTRLTIGVGAGPTKTLAKSAQWASKEWKQFHGVLA
                     LTRGNPQRTRKLLSLQPVEEIWGVGNRIARKLNVLGIKTALDLALTNPAFIRKNFSVVL
                     ERTVRELNGESCLSLEEAPPTKQQIVCSRSFGVKITEYESLRQAICQHAERASEKLRKE
                     HQYCRHISVFIKTSPFAIKEPYYGNVATEKLLTPTQDTRDIIAAATTALERIWRDGHRY
                     AKAGVMLNDFTGSGVSQLQLFDERPPRPHSAELMRVLDGINNSGLGKVWFAGRGMAPEW
                     QMKREMLSPAYTTRWSDIPAAKLA"
                     /name="Y-family DNA polymerase"
     gene            complement(5296..5727)
                     /gene="umuD"
                     /locus_tag="JJ438_27130"
     CDS             complement(5296..5727)
                     /gene="umuD"
                     /locus_tag="JJ438_27130"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="UMJ74200.1"
                     /translation="MKLQLFSTGKELPPQAHPLFADLASCGFPSPAADYVESDLDLHDY
                     CIRHPSATYYLRASGDSMADGSLYNGDLLVVDSAEKPRHGDIVVASMQGEFTVKRLLLT
                     PRLTLQPMNASWSPIYPDPDELDIFGVVTHIIHRPREMY"
                     /name="umuD"
     gene            6133..6756
                     /locus_tag="JJ438_27135"
                     /pseudo=""
     CDS             6133..6756
                     /locus_tag="JJ438_27135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="group II intron reverse transcriptase/maturase"
     gene            6822..7526
                     /locus_tag="JJ438_27140"
     CDS             6822..7526
                     /locus_tag="JJ438_27140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UMJ74201.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            7581..8057
                     /locus_tag="JJ438_27145"
                     /pseudo=""
     CDS             7581..8057
                     /locus_tag="JJ438_27145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011899415.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /name="GIY-YIG nuclease family protein"
     gene            complement(8433..9701)
                     /locus_tag="JJ438_27150"
     CDS             complement(8433..9701)
                     /locus_tag="JJ438_27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011191342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISApu1 family transposase"
                     /protein_id="UMJ74202.1"
                     /translation="MTIINANYYLEQLLAPAALERIARLCKFCLRQRAITPAMLVPALL
                     RAMGGDQVNDIAGLHRHFNALQLVNTHQVSYKPFHNQLRKESFALFMKALVERAIALRI
                     DHQLKAASLGAFKQVLLHDGTSFAVHRRLAADFPGRFKTISPAAIECHMTMSLSEQSPL
                     CMSVSADTAGERQFLPEAHTLTNCLLLADAGYIDRAWFEQVNDAGGFYLVRGTKSLNPK
                     IIQAWRGDGREVPKLAGLSLREAGRRRCRAEVLDMVVKSGQVEYRLIRRWFAEEKRFCL
                     WMTNLPRAAWSAEQVMSLYRCRWQVELLFKEWKSHNRLKGFVTGEKAIAEGLVWTSLLS
                     LVMKRRVAQSVMSGALSMLKASKNSATWWLPLLEAVAHRALTEIRERLEWAADYLAKNA
                     CRTKQRKSIQNRTLEGVLNGLAA"
                     /name="IS4-like element ISApu1 family transposase"
     gene            complement(10019..10390)
                     /locus_tag="JJ438_27155"
     CDS             complement(10019..10390)
                     /locus_tag="JJ438_27155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019838990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74203.1"
                     /translation="MTQERIQTRYPLGGPFATQAELEQAITQAITTHRQDFFPLLERLV
                     DVGDTRVNLSQENPLRVLSIELADGREGVAHINYESNFAESCLIINEYDQHQTSLAFRL
                     DGDALIFDVELPIAWNFNN"
                     /name="hypothetical protein"
     gene            10547..10996
                     /locus_tag="JJ438_27160"
                     /pseudo=""
     CDS             10547..10996
                     /locus_tag="JJ438_27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011222061.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /name="IS4 family transposase"
     gene            complement(11030..13927)
                     /locus_tag="JJ438_27165"
     CDS             complement(11030..13927)
                     /locus_tag="JJ438_27165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="UMJ74204.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEVMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            14000..14704
                     /locus_tag="JJ438_27170"
     CDS             14000..14704
                     /locus_tag="JJ438_27170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UMJ74205.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            14754..14864
                     /locus_tag="JJ438_27175"
                     /pseudo=""
     CDS             14754..14864
                     /locus_tag="JJ438_27175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'') family aminoglycoside
                     nucleotidyltransferase"
                     /name="ANT(3'') family aminoglycoside
                     nucleotidyltransferase"
     gene            14924..15748
                     /gene="blaOXA"
                     /locus_tag="JJ438_27180"
                     /pseudo=""
     CDS             14924..15748
                     /gene="blaOXA"
                     /locus_tag="JJ438_27180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722315.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class D beta-lactamase"
                     /name="blaOXA"
     gene            15948..16265
                     /locus_tag="JJ438_27185"
                     /pseudo=""
     CDS             15948..16265
                     /locus_tag="JJ438_27185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            16448..17308
                     /locus_tag="JJ438_27190"
     CDS             16448..17308
                     /locus_tag="JJ438_27190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A broad-spectrum beta-lactamase TEM-1"
                     /protein_id="UMJ74183.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="class A broad-spectrum beta-lactamase TEM-1"
     gene            complement(17458..17829)
                     /locus_tag="JJ438_27195"
                     /pseudo=""
     CDS             complement(17458..17829)
                     /locus_tag="JJ438_27195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(17894..19144)
                     /locus_tag="JJ438_27200"
                     /pseudo=""
     CDS             complement(17894..19144)
                     /locus_tag="JJ438_27200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124600.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(19219..19887)
                     /locus_tag="JJ438_27205"
     CDS             complement(19219..19887)
                     /locus_tag="JJ438_27205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="UMJ74206.1"
                     /translation="MAQAAARGQLDLHYQPLVDLRDHRIAGAEALMRWRHPRLGLLPPG
                     QFLPLAESFGLMPEIGAWVLGEACRQMHKWQGPAWQPFRLAINVSASQVGPTFDDEVKR
                     VLADMALPAELLEIELTESVAFGNPALFASFDALRAIGVRFAADDFGTGYSCLQHLKCC
                     PITTLKIDQSFVARLPDDARDQTIVRAVIQLAHGLGMDVIFRRRLHQLIGRNGCCAASS
                     "
                     /name="EAL domain-containing protein"
     gene            complement(19923..20159)
                     /gene="merE"
                     /locus_tag="JJ438_27210"
     CDS             complement(19923..20159)
                     /gene="merE"
                     /locus_tag="JJ438_27210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum mercury transporter MerE"
                     /protein_id="UMJ74184.1"
                     /translation="MNAPDKLPPETRQPVSGYLWGALAVLTCPCHLPILAAVLAGTTAG
                     AFLGEHWGVAALALTGLFVLAVTRLLRAFRGGS"
                     /name="merE"
     gene            complement(20156..20518)
                     /gene="merD"
                     /locus_tag="JJ438_27215"
     CDS             complement(20156..20518)
                     /gene="merD"
                     /locus_tag="JJ438_27215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury resistance co-regulator MerD"
                     /protein_id="UMJ74185.1"
                     /translation="MSAYTVSQLAHNAGVSVHIVRDYLVRGLLRPVACTTGGYGVFDDA
                     ALQRLCFVRAAFEAGIGLDALARLCRALDAADGAQAAAQLAVLRQLVERRRAALAHLDA
                     QLASMPAERAHEEALP"
                     /name="merD"
     gene            complement(20536..22230)
                     /locus_tag="JJ438_27220"
     CDS             complement(20536..22230)
                     /locus_tag="JJ438_27220"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="UMJ74186.1"
                     /translation="MSTLKITGMTCDSCAVHVKDALEKVPGVQSADVSYAKGSAKLAIE
                     VGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLDKMRDLLGRNDKTGSSGALHIAVIG
                     SGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDG
                     GIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQL
                     NDGGERVVAFDRCLIATGASPAVPPIPGLKDTPYWTSTEALVSETIPKRLAVIGSSVVA
                     LELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFRMEGIEVREHTQASQVAYING
                     EGDGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVE
                     HIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVATVGYSEA
                     EAHHDGIKTDSRTLTLDNVPRALANFDTRGFIKLVVEEGSGRLIGVQAVAPEAGELIQT
                     AALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG"
                     /name="mercury(II) reductase"
     gene            complement(22282..22704)
                     /gene="merC"
                     /locus_tag="JJ438_27225"
     ARG             complement(22286..22704)
                     /name="merC"
                     /gene="merC"
                     /gene_name="organomercurial transporter MerC"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(22740..22850)
                     /locus_tag="JJ438_27230"
                     /pseudo=""
     CDS             complement(22740..22850)
                     /locus_tag="JJ438_27230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229640.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric transport protein periplasmic component"
                     /name="mercuric transport protein periplasmic component"
     gene            complement(22866..23563)
                     /locus_tag="JJ438_27235"
                     /pseudo=""
     CDS             complement(22866..23563)
                     /locus_tag="JJ438_27235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(23597..24307)
                     /locus_tag="JJ438_27240"
     CDS             complement(23597..24307)
                     /locus_tag="JJ438_27240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020321496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="UMJ74187.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFTHDRNILVGDNESGKSTILLALD
                     LVLSDSRHRVEALGVESLLSQSAVRQFQEGERRADQLPVLTADVFLSNGGDPDLNGRQN
                     LAGINADGLRMRIAPMTEEYGQDIHNVLQQDPDNFPYEYYSVRFSTFSGGHFASFRRYL
                     RHLLLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCTRHLSAINDTL
                     ETYQFGVRVMLPTC"
                     /name="AAA family ATPase"
     gene            complement(24381..24797)
                     /locus_tag="JJ438_27245"
     CDS             complement(24381..24797)
                     /locus_tag="JJ438_27245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="UMJ74188.1"
                     /translation="MNKTYMLDTCICSFIMREQPEAVLKRLEQAVLRGQRIVVSAITYS
                     EMRFGATGPKASPRHVELVDAFCARLDAILPWDRAAVDATTEIKVALRMAGTPIGPNDT
                     AIAGHAIAAGAVLVTNNTREFERVPGLVLEDWVR"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(24794..25024)
                     /locus_tag="JJ438_27250"
     CDS             complement(24794..25024)
                     /locus_tag="JJ438_27250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="UMJ74208.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRP
                     TWGSFAQFEKADPDFMAEREDVVSDEGRFNL"
                     /name="AbrB/MazE/SpoVT family DNA-binding domain-containing
                     protein"
     gene            24981..25442
                     /locus_tag="JJ438_27255"
     CDS             24981..25442
                     /locus_tag="JJ438_27255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74189.1"
                     /translation="MARLLPFLKMDTVLIISSWPTGLYDYVQYMQMQSICIVIAYADGK
                     YMRMPHLCRCPAYGYVEPMLYSLFSRSDPKKGSSGSDSAPPARSGPETQDVAVFPAVSD
                     HICCAPPLPRDRPLTTLKGRCGYSLTVVHFRKLRKARKVGSGQSGRQVI"
                     /name="hypothetical protein"
     gene            25586..25936
                     /locus_tag="JJ438_27260"
     CDS             25586..25936
                     /locus_tag="JJ438_27260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74190.1"
                     /translation="MFTAFNERNDFSYAFEKIRNAISAPGENNLYAATELGLGILLRKY
                     EQFRQELDAAGELGNWEYDLDTYNHCIAVLQRYFTGNPSGLTERDARIYSHYLQTEHKR
                     FVKLAEELAAGR"
                     /name="hypothetical protein"
     gene            25987..26730
                     /locus_tag="JJ438_27265"
     CDS             25987..26730
                     /locus_tag="JJ438_27265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74191.1"
                     /translation="MTDIQAATESIVAATSHPVSVQLINQGAGIWGNVATGLITGLLTG
                     GITLTGIWLTHYFTLKRERQASEDKMKKELHYIATELVFMLERYAEGCFRVVTDDGQDD
                     DAPQPERKAVTNYPELNLIDVSGDWRTLEPRLMYRIRELPVLQDEAHRAIAYAAEYSDP
                     PWHKDYFRERQYQFTRLGINAVILAVRLRKATGMPETRLTGHDEWSAVSVFRKVWRRER
                     ALRAAEATRNREWNQLVIPDGMSNQ"
                     /name="hypothetical protein"
     gene            26727..27503
                     /locus_tag="JJ438_27270"
     CDS             26727..27503
                     /locus_tag="JJ438_27270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="UMJ74192.1"
                     /translation="MSGLLSYSHPQQPAQMPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLVPPYPFVQLATLKQRTEK
                     AARTAGRAPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRTEKARIWDIT
                     DRTVRTWIGEAVEAAAVDGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFQMPEADAVAMLKGNI"
                     /name="phage integrase family protein"
     gene            complement(27561..27818)
                     /locus_tag="JJ438_27275"
     CDS             complement(27561..27818)
                     /locus_tag="JJ438_27275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74193.1"
                     /translation="MKLETIQIDNTVRSGLNSFTDGVIIRDTKVLITLNLPDGQKTTIE
                     GEWRHMSDANRLSERITMLQHAIYEQYEEYRADIPVSWSR"
                     /name="hypothetical protein"
     gene            complement(27947..28051)
                     /locus_tag="JJ438_27280"
     CDS             complement(27947..28051)
                     /locus_tag="JJ438_27280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMJ74194.1"
                     /translation="MRSFTIMSLLETFLTASQGATILFLAMLIYWQKR"
                     /name="hypothetical protein"
     ARG             16449..17305
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15390..15748
                     /name="OXA-9"
                     /gene="OXA-9"
                     /gene_name="OXA beta-lactamase; OXA-9-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="100.0"
                     /coverage="43.43"
     ARG             14925..15259
                     /name="OXA-9"
                     /gene="OXA-9"
                     /gene_name="OXA beta-lactamase; OXA-9-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="100.0"
                     /coverage="40.51"
     Typing          2..752
                     /name="IncR"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.335"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggatactc aagcactctt gccagctact aaaacgttta aaaaacgcgc cagtataaag
       61 caatctaacg aattgaccga agctgcatat tacctgcctc ttcaggcaaa acgtgtgctg
      121 tggttatgcc tcatgcaggc ctattttaat gacagccagg aagatgactc tgacgtattg
      181 ccgctcttca aaatcagcgt ttccgattac gtcaaatact tcaatgtcgc tacgtctgtc
      241 gccagtcgtg atgtgaaggc tggggtaaat gctctgggcg aatcaacggt taccttttat
      301 ccaaaagaag gtgagtttga agaagttaaa cgtccgtggc tggctgaagc aggaatgaag
      361 cgaggccggg gttcctggca gattgaattt aactacaagg tcatgccatt cctggtcggc
      421 ttaacctccc agttcactac ctattctctc tatgactgtg gccagcttaa tagtgttcgt
      481 gtcatccggc tttatgaaag cctgtgtcag ttccggagca ctggtgtctg gatcaccaca
      541 catgactggt tatgtgaaag gtttatgctc cctgcctcgc agaaaaacaa tattgctgaa
      601 atgaagcgta ccttcctgga acctgctctg aagaaaatta atgagaagac gccattaaag
      661 gtaacatata ccactgaaga agatggtcgc ttgctgttta attttcttga taaaaaacaa
      721 tagtctgtaa tttttatttc ctcccccctt agtttgttgc tgacatatgg ggggatactg
      781 aacttgctgt gtttcccata gtgcttgcct aacttgacct gtttcccgca atcgcggctg
      841 tctgcgtagt tgacctgttt cccacagtcc gggccgtctg cggagttgac ctgtttccca
      901 cagtcccggt cgtctgcaaa gttgacctgt ttcccacagt cccggtcgtc tgcaaagttg
      961 acctgtttcc cacagtccgg gccgtacgcg gagttgacct gtttcccaca ctcccgaccg
     1021 tccgagaagt tgacctgttt cccatagtcc gggccgtccg agaagctgac ctgtttccct
     1081 tagtccgggc cgtccgcgaa gttgacctgt tccccacact cccggccgcc cgcgaagttg
     1141 acctgtttcc cacagtccgg gccgtctgca aagttgacct gtttcccaca gtcccggccg
     1201 cccgcgaagt tgacctgttt cccataatcc gggccgtccg cgaagttgac ctgttcccca
     1261 cactcccggc cgcccgtgaa gttgacctgt ttcccatagt ccgggccgtc cgcgaagttg
     1321 acctgtttcc catagtccgg agcgtccatt aaagttgacc tgtttcccac agaggatgga
     1381 aaactcttct tgtgctgagc gtaagagcta tctgccggaa cggttcctct tcgcttcctc
     1441 gccagttcgc tcgctacgct cggttacatg gctgcggcga gcgctgatac ataaggctca
     1501 gcattgcact ggtcgtaact aaaatcagaa tccttctgaa tgactctcct gtcttgcaag
     1561 ttgaatacct ttctcaaagc ccttttgtat gagttgctgt tgatggtcaa aagtgcgtct
     1621 gcgtgttgct gcagtgtgat ttagtagcac gcccgtcgag cttcatcccc cttctgttga
     1681 gagcgaaatc aaaacaatat gatttttttc ttgcaacatg acactttttg ttcaaaatga
     1741 caaaaaacgt catgaggtga taaatggaca atattgagca gttacggaaa gtcgctacac
     1801 gtgcaggtaa gcttctgaca tctttgagcg aaagtatccg acagcaaaaa gaggaattga
     1861 agcttaccga gttctatcag gaatacagca aagccgctct gtataagctg cctaagctca
     1921 gtaaaggcag tgttgagtat gctgtgtccg aaatggaagc cggtggctac atttttaaaa
     1981 agaaaccttc tggtaatacg atgaaatacg cgatgacgat tcagaatgtc atcgatctgt
     2041 ataaccatcg taaagtaccg aagtacaggg atcgcttcga taaagccttt acgatttttg
     2101 tatgtaatct taaaggtggt ggttccaaga cagtttctac cgcttcatta tcacatgctt
     2161 ttcgagctca tcctcagctt ctgttcgaag acctgcgtat tctggccatc gatttcgatc
     2221 cgcaggcatc tctgacaatg ttcctgagcc atgagaattc agtgggcttg gttgaaaata
     2281 cggctgctca ggccatgctc cagaacgtgt ctcgtgaaga attactttcc gattttatag
     2341 taccgtctat tatccctggt gttgatgtaa tccccgcttc cattgacgat gcattccttg
     2401 ctgaaggctg gaagggattg tgtgaagaac atctgccagg gaaaaatatt catgcggtgc
     2461 ttaaagagaa cattatcgac aagctccagc atgactacga ctttattttc cttgatagtg
     2521 gtcctcacct tgatgcgttc ctgaaaaact gcattggggc ggcagacctg atgttgaccc
     2581 ctcttccacc ggcgacggtt gattttcatt cttccctgaa gtttgtggcc agcctccctg
     2641 ccctcataga ttccatcgaa atggatgggc acacctgcaa tctcatcggt aatgtcggct
     2701 tcatgtccaa gatcctgaac aagtctgatc acaaaatttg ccatagtcag gccaaagagg
     2761 ttttcggtgc cgatatgcta gacatggttc tgccaagact ggatggtttc gaacgttgtg
     2821 gggagacttt tgacacagtt atttcagcaa atccagcaac ctatgatgga agtacagagg
     2881 cactaaaaag cgcaaaatca gcagcggaag actttgcgaa ggcagtcttt gatcgcatcg
     2941 agttcattcg tactaacgga ggtatgtgat gtcgaatgag aaaagaaaaa ccatcggcag
     3001 acagttaaat actcaggcgt caatactcga aatggctgac accggtagaa gtcaggtatt
     3061 taccttaaaa accggcagga aggtaacgtt caggtttgtt cgggtgcctg catctgaagt
     3121 tgaaagtaag accttcgtaa accaggaaaa caatggaaga gatcaacttg cactgaccag
     3181 ggagtctctg aaatccatta tccagacgat taagtttcag cagttctttc cctgtattgg
     3241 tattaagcaa agtgaaagga ttgagatact ggatggttca agacggcgag cctcagcaat
     3301 ttttgtccgt acaggccttg atgtaatggt taccgaagaa catttatcag ctgatgaagc
     3361 tcgccaactg gctaaagata tccagacagc taaagaacat aatcttcggg agattggtct
     3421 gagattgatc gctcttaaag agtccggatt taatcaaaag gaaattgctg aactggaggg
     3481 attatctcag gctaaagtta ccagggcgct gcaggcggcg gccgtaccgc aagacttaat
     3541 ttctctgttc ccggttcagt cggagctatc gtttagtgat tataaacttc ttttagaagt
     3601 taatgaaaaa ctcggtgaaa agggattaac gcctgaagaa ctcattcagt ctgtatcagc
     3661 tcagctcgat gcaattttga gtgatggcga gcgaccagaa gacgaacaga aagccagtat
     3721 tctgaagctg atttctcagg catctcaggc attgatagat ccatctccca aggaaaagtc
     3781 agtggtttcc ccactctggt cttttgaaga aaaggacaag ttcgcgcgta agcgtgtgaa
     3841 agggcgcacg ctgacttatg agtttagccg tatgtcaaaa gtgattcagg atgaactgga
     3901 caaggctatc aacgaagtcc ttgacagaaa tttgagtcaa taatttcgcc atggcgattt
     3961 cacatctaac ttattgtaat taggcagttt aggttgagaa tttcacggtg aaatcgccat
     4021 ggtttcacgc cagtttcgct gcaggaatat ctgaccatcg tgtcgtataa gcaggagaaa
     4081 gcatctcccg tttcatctgc cattccgggg ccataccccg ccccgcaaac catactttac
     4141 ccagccctga gttgttgatc ccgtccagaa ccctcatcag ctcagcactg tgagggcgtg
     4201 gcgggcgttc gtcgaacagt tgcagctgcg aaactccgga gccggtgaag tcattcagca
     4261 taactccggc tttggcatac cggtgcccat ccctccagat acgctccaga gccgttgtag
     4321 cggctgcaat gatgtccctg gtgtcctgag tgggtgtaag aagtttttcc gtagccacgt
     4381 tgccgtagta aggctcttta atggcgaacg gagacgtttt gatgaaaacg gaaatatgcc
     4441 ggcaatactg gtgctcttta cgcagttttt cagaggcccg ctctgcgtgc tgacagatag
     4501 cctgacggag tgactcgtac tccgtgatct tcacgccaaa actgcggctg cagacaattt
     4561 gctgtttcgt cggaggggct tcctcaagcg aaaggcagct ttccccgttc agttcccgta
     4621 ccgttcgctc aaggacgaca gaaaaatttt tgcggatgaa ggccgggttc gtcagagcca
     4681 gatcgagcgc ggtttttatg cccagcacat ttagcttgcg tgcaatacgg ttacccaccc
     4741 cccagatttc ttcaaccggc tgcagtgaaa gcagtttccg cgtcctttgc ggatttcccc
     4801 tggtcagagc gagtacgcca tgaaactgtt tccactcttt tgaggcccac tgggctgatt
     4861 ttgcgagggt tttcgttggt ccggcgccca cgccaatggt caggcgggta cagtcataca
     4921 cctgctgacg cagctgccgg gcgaagtcct caagccccat acagtgctcc acgccggtca
     4981 ggtcgaggaa catctcatca attgaatact gttccaccct gggggccagt tcctccaggc
     5041 agttcatcac gcgcgccgat atcgaggcgt aaagttcata attacttgaa aacgcatata
     5101 ttttttccgg gtatctttcg ttttttatct gaaaccacgg agttcccatt ttgatccagg
     5161 gcttcgcctc ggcactgcga gcgattacat tcccgtcgtt gttgctcagg acgactatcg
     5221 gctttccttt caaatccggg cggaaaacac gttcacagct ggcatagaag ctgttcacat
     5281 cggccagggc aaacatcagt acatctccct cgggcggtgg atgatatgcg tgacgacgcc
     5341 aaagatatcc agctcgtcgg gatcaggata aatcggcgac caggaggcat tcatgggctg
     5401 cagcgtcagt cgcggcgtca gcagaagccg tttcaccgta aactccccct gcatgctggc
     5461 gacaacgata tcgccgtgcc gcggcttttc agcactgtcc acaaccagca gatcgccatt
     5521 gtacagactg ccgtcggcca tgctgtctcc gctggcacgc aggtagtacg tcgcgctcgg
     5581 atgccgtatg cagtaatcat ggagatccag atcggactcg acatagtcag cagcagggct
     5641 gggaaaaccg cagctggcca gatcggcaaa caatggatgg gcctgtggcg ggagttcttt
     5701 cccggtgctg aaaagttgta gtttcatctt tcctcctgac actctaattt tactggttat
     5761 acatacagtg tgcgccggga gaccggtaga gatcaagggg tgaaagtccc cgaccattga
     5821 aggaccagca atccacaagg tccccgagtc atgcgttgca taccgcgagg tatggggcga
     5881 agcgttgaca ggggtgttga caggccagcc attgagccac gaaatgtata ttaaattacc
     5941 gggtgccgac gttgtactgt taacggaagg caacatcata gggtgcgata ctgcgagtgc
     6001 cacatggacc cggcggggtc tgagaccctg gcatgtcaat acgatctcta cgcgggaacc
     6061 gggagatctc ccctctgacc atctgccagt gtcggagatg gcccgcaccg ggaagacgag
     6121 gagtcatagc cggtgatgta cggagaggag aagtcggact cgctcatagt agcggcgaag
     6181 caggcgaaca acccgaaagg agcggagtca gtggagcgaa ggagcggggc caaggggaac
     6241 gcggaacagc cacacatgcg ccggacacag agccgggaaa gcatgtcaca gaggctgtca
     6301 cgcgtgcggg aagctgcgaa gcagcggaag aaagaacggt ttacagcatt gttccacctg
     6361 ctgacagtcg aagcactgga agccgcattc ctctccctga gcaggaaagc ggccgccgga
     6421 gtggatggca tcaggtggat ggactacgcc ggaaacatga agaacaacat aacagatctg
     6481 caccggaggc tacatcaggg cagctacagg gcgcagcccg gcaggcgtca ctacatccca
     6541 aaagcggatg gaaaacaacg cccgctcggc atcgcctcgc tggaggacaa gatcgtccag
     6601 tatgcgctgg tgaaaatcct gaacgcagtc tatgaaaacg actttatggg gttctcatac
     6661 gggttcagac ccgggcgaag ccagcacgat gcactggacg cactggccac agggctggta
     6721 cgcactaacg taaactgggt actggatgcc gacatcaggg cactgttgca aatagtcggt
     6781 ggtgataaac ttatcatccc cttttgctga tggagctgca catgaaccca ttcaaaggcc
     6841 ggcattttca gcgtgacatc attctgtggg ccgtacgctg gtactgcaaa tacggcatca
     6901 gttaccgtga gctgcaggag atgctggctg aacgcggagt gaatgtcgat cactccacga
     6961 tttaccgctg ggttcagcgt tatgcgcctg aaatggaaaa acggctgcgc tggtactggc
     7021 gtaacccttc cgatctttgc ccgtggcaca tggatgaaac ctacgtgaag gtcaatggcc
     7081 gctgggcgta tctgtaccgg gccgtcgaca gccggggccg cactgtcgat ttttatctct
     7141 cctcccgtcg taacagcaaa gctgcatacc ggtttctggg taaaatcctc aacaacgtga
     7201 agaagtggca gatcccgcga ttcatcaaca cggataaagc gcccgcctat ggtcgcgcgc
     7261 ttgctctgct caaacgcgaa ggccggtgcc cgtctgacgt tgaacaccga cagattaagt
     7321 accggaacaa cgtgattgaa tgcgatcatg gcaaactgaa acggataatc ggcgccacgc
     7381 tgggatttaa atccatgaag acggcttacg ccaccatcaa aggtattgag gtgatgcgtg
     7441 cattacgcaa aggccaggcc tcagcatttt attatggtga tcccctgggc gaaatgcgcc
     7501 tggtaagcag agtttttgaa atgtaaggcc tttgaataag acaaaaggct gcctcatcgc
     7561 taactttgca acagtgccag gagggccgta aggtcatgct aggtgacaaa ctcctcttgc
     7621 caaattacgc gcccattcca agcggctttg tctatgtgct cgcgacaaag agcacggacc
     7681 ctatattgat gcccttcatg caaaatctct acaagatagg tttcaccgag ggtaccgtcg
     7741 aagaccggat aaagcacgcc gagaaagaca agacgttcct gcaagccccg gttaggatca
     7801 tcacgacatt ccagtgtttc aacatgaaca cccacaaatt ggagaccttg gtgcacggtt
     7861 ttctcgccaa gcagcgcctc gatatcacct tgaagggggt tgatggcacc agctatgccc
     7921 cgagagagtg gttccatact ccattgacaa ccatccttga agttattcac cacattttgg
     7981 atggaacaat ctcgcagtac cgcatggaca atactaccgg taaggttgtt gcaaaaaaaa
     8041 cgaccaataa tgcgtaataa tgccaggcag cattggcacg gacctgctca tcggcagcca
     8101 aagggcccga ctgctctgcc gcttgctgca tccagtgcat ggcattgggg taatcaggtt
     8161 ggctggccag acgtttggcc aactcatatt gagccttacc attgccttga gtcgcggcat
     8221 tggataactc ggcatcagtg agtgaagttg tggaagagca ggccggtcgc cagctgtagg
     8281 agaggaataa cgtttcatac tgaacaatca agcacccctg ctcataccgt tttatatgaa
     8341 acatgaccaa aattaaagat tcatactaat tgctactacg aagtccgaat cgagcttcaa
     8401 ccgagtaata aagtatcatc atgtacagga ccttaagcgg cgagtccatt taaaacgcct
     8461 tccaaggtcc tgttctgtat cgactttctc tgcttggttc ggcaggcgtt cttggccaaa
     8521 taatcggcag cccattccaa tctttccctt atttctgtca gcgccctatg ggccactgct
     8581 tccaatagcg gtagccacca cgtcgcactg ttcttcgacg ctttcagcat cgatagcgcc
     8641 ccactcatca cactctgcgc gacccgtctc ttcatcacca gcgacagcag gctcgtccac
     8701 accaacccct cggcaatcgc tttctcgccc gtcacaaacc ccttgagccg gttgtgcgat
     8761 ttccactctt taaataacaa ctccacctgc caacggcagc gatacaggct catcacctgc
     8821 tctgctgacc atgctgctcg cggtaggttc gtcatccaca gacagaaccg cttttcctca
     8881 gcaaaccagc gccggatcaa ccggtactcg acctggccgg acttcaccac catatccagt
     8941 acctcggccc gacagcgtcg ccgtccggcc tctctcagag atagtcccgc cagcttgggt
     9001 acttcccgtc catcaccgcg ccaggcttgg attatcttgg ggttcaggct tttcgtgccg
     9061 cgcaccagat aaaatccgcc agcgtcgttc acctgctcaa accaagccct gtcaatgtaa
     9121 cctgcgtcag ccagcagcag gcagttggtc agcgtgtggg cttcaggcag aaattgccgt
     9181 tcccctgcgg tatcggcaga cacactcatg cacaacgggc tctgctccga cagtgacatg
     9241 gtcatatggc actcgatagc tgccggactg atggtcttga accggccggg aaaatcagca
     9301 gcaaggcgcc gatgcaccgc aaaggaggtg ccatcgtgca gtaacacctg cttgaacgcg
     9361 ccgagggagg ctgctttgag ttgatggtcg atacgcaagg cgatggcccg ctcgaccagg
     9421 gctttcataa acagggcaaa gctctctttg cgcagctgat tgtgaaacgg tttgtaagaa
     9481 acctgatggg tgtttaccag ttgcaaggca ttgaaatggc ggtgtaaacc ggcaatgtca
     9541 ttgacctggt cgcctcccat ggcccgcagc agtgcaggta cgagcatggc tggggtaatg
     9601 gcacgctgac gcagacaaaa cttgcagagc cgagcaatgc gctcgagtgc ggcgggagcc
     9661 aagagttgct ccagatagta attagcgttg ataatagtca taggcttcgc gcgtgttgat
     9721 tttgtttggc gataaaatca gatcacaaac gaagcctttt ttatatctat ttcaattggt
     9781 tgccgctaaa gatcctgtac atgagtgagg gttatggtgg ctatatgctg gatattgcta
     9841 ttcagatgac agccatatgg ggaagattac aggcgcctga aataacagca gagtatggag
     9901 tgactaccac ggctggaggt tggcacgggc tgatcccctc tccctttggg agagggttag
     9961 ggtgagggga gctggctgac cgggtgtagc aaccaggcgg cattacaccg ctgaatcttc
    10021 agttattgaa attccacgcg atcggcagtt cgacgtcgaa gataagtgca tccccgtcga
    10081 ggcgaaaggc caggctggtc tggtgctggt cgtattcgtt gataatcagg cagctctcgg
    10141 cgaagttgga ctcgtagttg atatgggcca ctccttcacg gccgtcagcg agttcgatgc
    10201 tgagcacccg cagcgggttc tcctgactga ggttgacccg ggtgtccccc acgtccacca
    10261 gccgttccag cagagggaag aaatcttgtc tgtgggtcgt tatggcctgg gtgatggcct
    10321 gctccagctc agcctgggtg gcgaaggggc cgccgagtgg gtagcgggtc tggatccttt
    10381 cctgagtcat tgcgtttcct cctgaactga gatgtggcaa cagtttggcc gctgcagtga
    10441 cctgtcatgt acaggatctt tagctacaac caattgaaat agatagaaaa aaggcttcgt
    10501 ttgtgatctg atttaatcgc aaaaaaaaac cgacacgccc gaagccatga ctattataaa
    10561 tgcaacccag tacctcaagc aacttcatag ctcttctgaa ctcaaccgga tcggtaaatt
    10621 taccggtttt tgtcagcgac tccgggatat ccagcctgcg agactactcc cggctctgct
    10681 ctcagggctt ggttgcgaca aggtggatgg tattgctggt ttgcatcgcc atttcaatgc
    10741 gttgcagctc catgatactg accaaatagc gtataaaccc tttcacaacc agttacgcaa
    10801 gcagggtttt cccttgttca tgcgcgcact ggttgaacga gccatcgcct tacgcctcaa
    10861 ggagtgtcta ccggacgccc acggactggc aggctttgag caggtactgc tgcaggacgg
    10921 gtcgtcattc gcgttacatc cgcaattggc agaacatttc ccgggccgat tcaataagca
    10981 cagccccgct gcggtagggg tcggttccgg ctgagggcga aatgacaccc taagctttcg
    11041 gttccttggg ccaaagatat tcgccagtca gtagaatgtg cgcccagccc aatggggata
    11101 tgtggggaag aaattcaggg ggaacatcca acccttcgtt ccgccgctcc gtgacggcat
    11161 gaccaagatg gacggtattc cagtaaatga tcaccgcagt caataaattg agcccagcga
    11221 ttcggtagtg ctgcccctct gtcgtgcgat cgcgaatttc cccctgcctc ccgatacgga
    11281 gcgcattttt gagcgcatgg tgggcctctc ccttgttaag accgatctga gcacgccgct
    11341 gcatgtccgt atccaggatc cactcaataa tgaaaagggt ccgttcaata cgaccaactt
    11401 cacgaagcgc aactgcaagg ttgttttgtc gtgggtaaga agcgagcttg cgcaggagtt
    11461 ggctgggcct gattttgcca gcggtcatcg tcgcggcaca acggaaaata tcaggccagt
    11521 tcgcaacgat aagatcctcc cgggcttttc cacctaccaa cttgcgtaac tccctggggg
    11581 tcgtatcggg attaaatacg tacaaccgct tcgatggcag atccctgatt cgcagaacga
    11641 gattgtagcc gagcaggcta ctggctccga acaaatggtc ggtgaatcct gctgtatcgg
    11701 catactgttc gcgaacatgg cgaccgacct cgttcatcag tagtccatcg agaatatacg
    11761 gtgcctcgct cacggtcgcc gggatcgact gacaagcgaa tggcgcgaac tggtcgctta
    11821 cgtgagtata cgctttgagg ccgggaacag aaccatattt ggcattgacc atgttcatga
    11881 cttcgccatg ccgcgctgtc gggaaaaact gaccatcgct cgatgctgac gtgcccatcc
    11941 cccagacgcg tgacatcggc agtttaccct gcgcggccac cacaattgcc aatgcctggt
    12001 tcatggcttc gctttcaaca tgccagcggg caaggcgtga gagctgccag taatcatgcg
    12061 tgtttgtagc ttccgccatc ttacgcaggc ccagattgag cccttcagcg agcaggacgt
    12121 tgagcagacc gatccggtcg cgacatggag ccccggttct cagatgggta aacgcatctg
    12181 tgaaaccaag ggctgcatca acttcaagca gcatgtcggt aatccgaacg gacggcattc
    12241 ggcgatacag atccagtatg agtgcctcgg caccatccgg cacgtctgct gtcaacctgt
    12301 cgatccgcaa cgttccatct tctatgctac cgtgcggaat agtgccgtta cgggcagccc
    12361 gggccagccg cttaagagcg atcgtgagtc gcgcctttct gtctgccagc caatcctgtg
    12421 ggttggaagg cacggccagt tttgcatttt cctgcgccgc gatcatcggc accagtacct
    12481 gcttgaggtc accatagcgg cgcgaatgag cgagccagac atctccggaa cgaaaagcat
    12541 cccggaggtg aaagagtacc gccacttccc aaagacgggt atctcctttt tcctgagctc
    12601 gtaaatgacg gttccatttg gagctgggcc gcaggaaacg cctttctggc gatgcaacac
    12661 ctttcatctc tccgatcgac aaagctgctg ctaccaatgg tccggcgacc ggcgcggctt
    12721 cgagcttcag acagcgcaac atgcggggcg cataacgacg aaagcgatgg tatccctgcc
    12781 cgacatatgc aagaggctca tcggctagcg tgttgctgag ttgagtccct gtcgctacca
    12841 gttgagcgag ccggtcccat gcaaccgaac tggcgacagc catctccagc ggggttccgt
    12901 cactgcgggc ctcaagcaac gaagctccca gcgcggtgaa ggtacggatc gtatccgtga
    12961 gtgtggcttt agagccggaa attgtttcgt catgctggcg cttcgcttcc cgccaggttt
    13021 ttcctacgat cctgtcatgg gtttcgacta tggcatcagc aatcgccgct tcccactcca
    13081 caacacagac ggcaaggatc gcccagcggc ggtccgaagt gatgtcacgc aaaccgtcgg
    13141 tgaagtagcg ttcaccctgc cgacgcagcc gggcaatgcg atgggcaggt atgctggcca
    13201 aagcactatg attgatattc agggtacgca gaaattcgag cctgtcgagc aaacggttag
    13261 cagcagccga gttgttacca acctcgaagt tgcgaagcca gatgaaacga ctgatattgc
    13321 cggcgagcat ttcactcaga agtttgtcca ggtgatcgcg aacatccgct gttaaatttt
    13381 ccgcaatccg cgtttcaatc cgccgctcag cggcgaccag agcatccgcg cacaagcgct
    13441 cgattgtcga tactgcgggc agaatggtgg aagtttcccg acaccgcaca ataaaacgat
    13501 gagcaagatc ctcgtttgat ctggcatctt cggcctggcc gaaagtccac tcccgcagat
    13561 cacgggcacc acggcccgtg aaggtcttgt agccgtaaat ttcgcgcagc gtgtccatgt
    13621 gctgctgacg ggtttggcgc cgtgtggcat aagtgagaag cgcatcagcc ggaactccaa
    13681 gctgagcacc gacgaaggaa aggacttcac gcgggatcat ctcaccagga gccagtgcac
    13741 ggcccggata tcgtaaggca caaagttgca gggcaaagcc aatcctgttt tccggtctgc
    13801 ggcgctgcct aatgttttcc aggtcatcat cgcccagcgt gtagaacttc agtagcgaca
    13861 gttcgtccgt gggcagatcg aacagcgctg ctcgctgccg ttcggtgaaa atatggcgtc
    13921 gtgacataca aattcgggca ctgttgcaaa tagtcggtgg tgataaactt atcatcccct
    13981 tttgctgatg gagctgcaca tgaacccatt caaaggccgg cattttcagc gtgacatcat
    14041 tctgtgggcc gtacgctggt actgcaaata cggcatcagt taccgtgagc tgcaggagat
    14101 gctggctgaa cgcggagtga atgtcgatca ctccacgatt taccgctggg ttcagcgtta
    14161 tgcgcctgaa atggaaaaac ggctgcgctg gtactggcgt aacccttccg atctttgccc
    14221 gtggcacatg gatgaaacct acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc
    14281 cgtcgacagc cggggccgca ctgtcgattt ttatctctcc tcccgtcgta acagcaaagc
    14341 tgcataccgg tttctgggta aaatcctcaa caacgtgaag aagtggcaga tcccgcgatt
    14401 catcaacacg gataaagcgc ccgcctatgg tcgcgcgctt gctctgctca aacgcgaagg
    14461 ccggtgcccg tctgacgttg aacaccgaca gattaagtac cggaacaacg tgattgaatg
    14521 cgatcatggc aaactgaaac ggataatcgg cgccacgctg ggatttaaat ccatgaagac
    14581 ggcttacgcc accatcaaag gtattgaggt gatgcgtgca ctacgcaaag gccaggcctc
    14641 agcattttat tatggtgatc ccctgggcga aatgcgcctg gtaagcagag tttttgaaat
    14701 gtaaggcctt tgaataagac aaaaggctgc ctcatcgcta actttgcaac agtgccaggc
    14761 aggcttatct tggacaagaa gatcgcttgg cctcgcgcgc agatcagttg gaagaatttg
    14821 ttcactacgt gaaaggcgag atcaccaagg tagtcggcaa ataatgtcta aaacaaagtt
    14881 atgcacctat taagcgcaca gcggagcaat gaaggatacc ttgatgaaaa aaattttgct
    14941 gctgcatatg ttggtgttcg tttccgccac tctcccaatc agttccgtgg cttctgatga
    15001 ggttgaaacg cttaaatgca ccatcatcgc agacgccatt accggaaata ccttatatga
    15061 gaccggagaa tgtgcccgtc gtgtgtctcc gtgctcgtct tttaaacttc cattggcaat
    15121 catggggttt gatagtggaa tcttgcagtc gccaaaatca cctacgtggg aattgaagcc
    15181 ggaatacaac ccgtctccga gagatcgcac atacaaacaa gtctatccgg cgctatggca
    15241 aagcgactct gttgtctagt tctcgcagca attaacaagc cgtctgggag ttgatcggtt
    15301 cacggaatac gtaaagaaat ttgagtacgg taatcaagat gtttccggtg actcggggaa
    15361 gcataacggc ttgacccagt catggctgat gtcgtcgctc accatatctc ccaaggagca
    15421 aattcagttt cttctacgct ttgtcgcgca taagctgcct gtatccgaag cggcttatga
    15481 catggcgtat gccacaatcc cgcagtacca ggcagccgaa ggatgggctg tacatggaaa
    15541 aagcggcagc ggctggcttc gggacaataa cggcaagata aatgaaagtc gtccgcaggg
    15601 ctggttcgtg ggctgggctg aaaaaaacgg acggcaagtt gttttcgccc gattggaaat
    15661 aggaaaggaa aagtccgata ttcccggcgg gtctaaagca cgagaggata ttctcgtgga
    15721 attacccgtg ttgatgggta acaaatgata tgtggcgtca tcgagagcag atgcataacc
    15781 ctgcgctcga gcggacctcg cgcataaagc cgcgcgagtc cgctcacctt gaacgttaga
    15841 tgcactaagc acataattgc tcacagccaa actatcaggt caagtctgct tttattattt
    15901 ttaagcgtgc ataataagcc ctacacaaat tgggagatat atcatgaaaa gagtttgatg
    15961 ctcagggtgt agcggttcgg tttattgacg acgggatcag taccgacggt gatatggggc
    16021 aaatggtggt caccatcctg tcggctgtgg cacaggctga acgccggagg atcctagagc
    16081 gcacgaatga gggccgacag gaagcaaagc tgaaaggaat caaatttggc cgcaggcgta
    16141 ccgtggacag gaacgtcgtg ctgacgcttc atcagaaggg cactggtgca acggaaattg
    16201 ctcatcagct cagtattgcc cgctccacgg tttataaaat tcttgaagac gaaagggcct
    16261 cgtgatacgc ctatttttat aggttaatgt catgataata atggtttctt agacgtcagg
    16321 tggcactttt cggggaaatg tgcgcggaac ccctatttgt ttatttttct aaatacattc
    16381 aaatatgtat ccgctcatga gacaataacc ctgataaatg cttcaataat attgaaaaag
    16441 gaagagtatg agtattcaac atttccgtgt cgcccttatt cccttttttg cggcattttg
    16501 ccttcctgtt tttgctcacc cagaaacgct ggtgaaagta aaagatgctg aagatcagtt
    16561 gggtgcacga gtgggttaca tcgaactgga tctcaacagc ggtaagatcc ttgagagttt
    16621 tcgccccgaa gaacgttttc caatgatgag cacttttaaa gttctgctat gtggcgcggt
    16681 attatcccgt gttgacgccg ggcaagagca actcggtcgc cgcatacact attctcagaa
    16741 tgacttggtt gagtactcac cagtcacaga aaagcatctt acggatggca tgacagtaag
    16801 agaattatgc agtgctgcca taaccatgag tgataacact gctgccaact tacttctgac
    16861 aacgatcgga ggaccgaagg agctaaccgc ttttttgcac aacatggggg atcatgtaac
    16921 tcgccttgat cgttgggaac cggagctgaa tgaagccata ccaaacgacg agcgtgacac
    16981 cacgatgcct gcagcaatgg caacaacgtt gcgcaaacta ttaactggcg aactacttac
    17041 tctagcttcc cggcaacaat taatagactg gatggaggcg gataaagttg caggaccact
    17101 tctgcgctcg gcccttccgg ctggctggtt tattgctgat aaatctggag ccggtgagcg
    17161 tgggtctcgc ggtatcattg cagcactggg gccagatggt aagccctccc gtatcgtagt
    17221 tatctacacg acggggagtc aggcaactat ggatgaacga aatagacaga tcgctgagat
    17281 aggtgcctca ctgattaagc attggtaact gtcagaccaa gtttactcat atatacttta
    17341 gattgattta aaacttcatt tttaatttaa aaggatctag gtgaagatcc tttttgataa
    17401 tctcatgacc aaaatccctt aacgtgagtt ttcgttccac tgagcgtcag accccttgtt
    17461 gaggatttta cccagaaacc ggtatgcagc tttgctgtta cgacgggagg agagataaaa
    17521 atcgacagtg cggccccggc tgtcgacggc ccggtacaga tacgcccagc ggccattgac
    17581 cttcacgtag gtttcatcca tgtgccacgg gcaaagatcg gaagggttac gccagtacca
    17641 gcgcagccgt ttttccattt caggcgcata acgctgaacc cagcggtaaa tcgtggagtg
    17701 atcgacattc actccgcgtt cagccagcat ctcctgcagc tcacggtaac tgatgccgta
    17761 tttgcagtac cagcgtacgg cccacagaat gatgtcacgc tgaaaatgcc ggcctttgaa
    17821 tgggttcatg tgcagctcca tcagcaaaag gggatgataa gtttatcacc accgactatt
    17881 tgcaacagtg cccatcggcg tagtagtgga tgtggtcgat gacaaagccg gtgcgggtca
    17941 gcgtgcgccg gaggatcggc agaaaatcga ccaggaacga agtagcgcgt gtgacgacgg
    18001 ccggtacgcc gacacgcgcc acggcctcgg cccagcgcgc ggccggcggt tggagcaggc
    18061 cgttgtgcac cgaaccgtgg taggtgccga ccgccaatgt gagccagcgc tctagctcgc
    18121 gcagcgtcag ggcggccttg ttttcggaat cgtagtcgcc gcgctggtca gggttggaga
    18181 aggtcgttcc cggcagttcg tcgtgaatca tctgcatcgc cgtgccgatg atccgttcca
    18241 cgatgccgcc atagtgcggc tgtcccagcg ggcgatagtc cagccggatg ccatgctgct
    18301 cgcaaccccg gcgcagggcc tcgctcttga actcggccgc gttgtctagg tagagcagca
    18361 agggcttgcc gctcatctgc caatccattt ccacgttcag tccttccagc caagggcgct
    18421 tgtcgcaggc gatatgcacg aggcacaggc caaccgaaac ggcagacggc gcttccagcg
    18481 tgacgaccat gccgagcacg cagcgggtga acacgtcgat ggcgagggtc aggtacgggc
    18541 ggccaatagg ttgccggtcg cggtcatcga ccacgatcag gtcgatgacc gtatggtcta
    18601 tctgcacctg ctccagcggc gcggtcacgg caggaggctc gccgcccaca ccttgtaggt
    18661 cacgagcggc atcctggcct tcccgccggc ggatgacctt gcgcgggtca aggctagcga
    18721 tccgtaaggc cacggtattg cgcgccggca ctcgcagttt ttgagccttg cacacctgag
    18781 tgacttcgcg gtgaaaggcc gctaggctgc gcttctgctt ggtcaggaac cgcttttgca
    18841 gtagctcgtg gatgacgcgc tcgaccggtt ccggcaagcg ccccttacct ttacctccac
    18901 cggactggcc gggcaccaga tccgtcacga ggccgctgcc ttgccgggca cgccggatca
    18961 gaacgtatac ctggcgccga gacaagccca gcgcctgagc cgccatatcg gccgcttcgt
    19021 gcccgaccgt ctccgactgc gccaacggac tgatgatctc cgcacgacgg cgcgcacgct
    19081 cccaagcctc atcaggcaga gtggccacgc cttgttctgg aatccgtggg gtgtccgtcg
    19141 ccatgctcac ctcgctttgg tgcacacgag tattgagcat agtcgagatt ggtgcagatc
    19201 acttctgata ttgaactgtc aggagctggc tgcacaacag ccattacgcc caatcaactg
    19261 gtgcagtcgt cttctgaaaa tgacatccat gcccagcccg tgcgcgagct ggatcaccgc
    19321 ccgcacgata gtttggtcac gggcatcatc cgggagcctg gcgacaaagg attggtcgat
    19381 tttcaatgtg gtgatggggc agcatttcag atgttgcagg caggaatagc cggtgccgaa
    19441 gtcgtcggcg gcgaagcgca cgccgatggc gcgcaaggcg tcgaaactgg cgaacagggc
    19501 tggattgccg aatgcgaccg attcggtcag ttcgatctcc agaagctcgg cgggcagggc
    19561 catatcggcc agcacccgct ttacctcgtc gtcgaacgtt ggcccaacct ggctggcgga
    19621 cacattgatg gcaagacgga acggttgcca tgccggtcct tgccacttgt gcatctggcg
    19681 acaggcctcg cccagcaccc acgcgcctat ttccggcatc aggccgaacg actcggccag
    19741 cggcaggaac tggccgggcg gcaacaggcc aagcctcgga tgccgccagc gcatcaacgc
    19801 ttccgcgcca gcgatccggt gatcgcgcag atcgaccagc ggctggtaat gcaggtcaag
    19861 ctgtccgcgc gccgccgcct gcgccaactc ggccgccgtc catccggcgg gctgcgaact
    19921 cgtcatgatc cgccccggaa ggcgcgcagc agccgcgtta cggccagaac gaacaagccg
    19981 gtcagcgcga gcgcggcaac accccaatgc tcgccaagga aggcaccggc ggtcgtcccg
    20041 gccagcacgg cggcgagaat cggcagatgg caggggcagg tcaacacggc cagcgcaccc
    20101 cacaggtagc cggaaacggg ttggcgcgtc tcgggcggca gtttgtcagg ggcgttcacg
    20161 gcaatgcctc ctcgtgcgcc cgctcggctg gcatggaggc cagttgcgcg tccagatggg
    20221 ccaacgccgc gcgccgccgc tcgaccaact ggcgcagcac ggcaagctgc gctgcggctt
    20281 gtgcgccgtc cgctgcgtcg agcgcacggc acagccgcgc cagggcatcc aggccgatac
    20341 ccgcctcgaa ggccgcgcgc acgaagcaca gccgttgcaa ggccgcatcg tcgaacacgc
    20401 cgtagccgcc cgtggtgcag gccaccggcc gtaacaagcc gcgcaccagg tagtcgcgca
    20461 cgatatgtac gctcacccca gcgttatggg ccagttgcga taccgtgtag gcgctcatcg
    20521 cacacctcct tgtcctcacc cggcgcagca ggaaagctgc ttcacatcct tgttgaaggt
    20581 ctgcgccgcg agcttcaacc cttcgaccat cgtcaggtag gggaacaact ggtcggccag
    20641 ttcctgcacc gtcatccggt tgcgaatcgc cagtgcggcc gtctggatca gttcgcccgc
    20701 ttccggggcc actgcctgca cgccgatcag tcgtccgctg ccttcttcaa ccaccagttt
    20761 gatgaagccg cgcgtgtcga agttggcgag cgcgcgcggc acgttgtcca gcgttagcgt
    20821 gcgactatca gttttgatgc cgtcatggtg cgcttccgcc tcgctgtagc ctacggtcgc
    20881 cacttgcggg tcggtgaaca ccacggccgg catcgcggtc aggttcaggg ccgcgtcacc
    20941 gccggtcatg ttgatcgcgg cgcgagtgcc ggccgctgcc gccacataga cgaactgcgg
    21001 ctggtcggtg cagtcgcctg cggcgtagat gtgttccacg cttgtacgca tgccggggtc
    21061 gatgacgata gcgccttgcg gggtgagcgt gacgcccgtc gcatccagtg ccagcttgcg
    21121 tgtgttgggc gcgcggccgg tggcgaccag cagcttgtcg gcgcgcagtt cgccgtgcgc
    21181 cgtggtgagc acgaattcgc cgtccccttc accattgata tacgcgacct ggctggcctg
    21241 ggtgtgttcc ctcacctcga tgccctccat gcggaatgcg gccgtgacgg cttcgcctat
    21301 agctgggtct tcgcggaaga acagcgtgct gcgagccagg atcgtcacct tcgctccgag
    21361 tcgggcgaac gcctgcgcca gctccagcgc caccactgat gagccaatca cggccaggcg
    21421 cttaggaatc gtctcgctga ccagcgcttc agtggaagtc cagtacggag tgtctttcag
    21481 gccgggaatc ggcggcacgg ccgggctcgc gccggtggcg atcaggcagc ggtcgaatgc
    21541 caccacgcgc tcgccgccgt cgttgagttg cacgatcagg ttgcgattgt ccttaaagcg
    21601 ggcggagccg tgcagcacag tgatcgccgg attgccctcc aagatgcctt cgtacttggc
    21661 gtggcgcagt tcatcgacgc gggcctgctg ctgggccagc agcgccgtgc gctggatggt
    21721 cggcgtggta gcggcgatgc cgccatcgaa cgggctttcc cggcgcagat gggcgatatg
    21781 ggcggcgcgg atcatgatct tggacggcac acaaccgaca ttgacgcagg tgccgccgat
    21841 ggtgccgcgc tcgatcagcg tgacacgtgc gccttgctcg acggccttca gcgccgctgc
    21901 catcgcggcc ccgccgctgc cgatgacggc gatatgcaat gcgccgctgc tacccgtctt
    21961 gtcgtttctg cccagcagat cgcgcatctt gtcgagcaat ccgcccggcg tcgaaactga
    22021 gggggcatcg gccagcgtgg cccgataacc gagtccagct acagcggccg tcagcgcgtc
    22081 gggtgacgtg ccgacctcaa tggcgagctt ggcgctgccc ttggcgtagg agacatccgc
    22141 tgattgcacg ccgggcactt tctccagggc gtccttgaca tgcactgcgc acgagtcgca
    22201 agtcatgccg gtgattttga gagtgctcat accatcgttc cttattcgtg tgggccgccg
    22261 tgtcgcacgg tcagccgtct ttcacaagcg cttggcgggg agttcgcagc cgtccggtcc
    22321 gcaacggcga tgcgccggcg acacgaagtc ccagatcgac accccaatca tcaaggccag
    22381 gccgacgtac atcaggttcg ccgtccacca gttgccgagc agccagaccg tggccgcaaa
    22441 cacgatggcc gggccgatca tgccgagcag actgcgcagc cattgccgat gactgaacca
    22501 acccagcgcg ttcgccagga aggccagcgc ggcaaacagc ggcagcaggc ggctgatgaa
    22561 cagtccctcg tactggctca agaagcccag cccgatggcc gcgccgaagc tggcgagggc
    22621 tggaaagcag gcggcgcagc ccatcgcgga aacgacgctg ccgagcgcgc cggttttatc
    22681 ggcaatgcgt gtcatcagtc ccatgaagcg gctctcgctg ttgtcgttgg cttgctggct
    22741 cactgcttga cgctggacgg atagccggcg tctgcggtgg ccttggtcag cttctgtacg
    22801 ctggccttgg tgtcgtcaaa agtgacgacg gcctcgcgct tctcgaagcc ggtaatgact
    22861 ccaatttact gatagtgttt tatgttcaga tagtgcccga tgactttgtc atgcagctcc
    22921 accgattttg agaacgacag ggacttcctg cccagccttg ccagatgctg tctcagattc
    22981 aggttgtgtc gctcaattcg ctgcgtgtaa cgcttactga tgacgtgcag ttttcccttc
    23041 agacgtgact catacatcgg ccagccgtcc gtcatccata ccaccacgtc aaaaactgac
    23101 agcaggctca gaagacgctc cagtgtggcc atagtgcgtt caccgaaaac gtgggctacc
    23161 accgccctgc gtatcctgtc atacgcgtaa aacagccagc gctgacgtga ttttgcaccg
    23221 acgtagcccc attgctcgtc catctccgca cagacaatga catcactgcc cggctgtatc
    23281 cgggaggtta ctgactgcgg cctgagtttt ttaaatggcg caaaatggtg ttgaggccca
    23341 cgcccattag tcgtgcggtg gcacggcaac cgacgccgtt catagccata tcaatgattt
    23401 tctggtgtgt accgggctga gaagcggcat aagtgaaggt gagctgccat gttttacggc
    23461 agtgagagca gagataacgt tgatgcccgg cagtactttt gccattacgc atcacgcctt
    23521 cagtagcgga acaggaggga cagcagacgg agactgaagc cacgggagca cctcaaaaac
    23581 accattatac actaaatcag caagttggta gcatcacccg cacgccaaac tgatacgttt
    23641 ccagcgtgtc gtttatggct gacagatgcc gggtgcagaa gtgcattttc tgttgccggt
    23701 aactgttttc aagccggtac cgatcggcca ccggcacatt gacgctgtaa actgtgcgcg
    23761 tatattcctg tgcggcgtgc tcgttatcga tgcgtgcact gtctaagagc agatggcgca
    23821 gatagcgtct gaagctggcg aaatgaccac cggagaaggt gctgaaccgc acggaatagt
    23881 attcataggg aaaattatcg ggatcctgct gtagtacatt gtgaatatcc tggccgtatt
    23941 cctccgtcat tggtgcaata cgcattctga gaccatccgc attgataccc gccagatttt
    24001 gcctgccgtt caggtcagga tctcccccat tactcaggaa aacgtcagct gtcagcacgg
    24061 gtaactgatc ggcgcggcgc tcaccttcct gaaactgcct tactgctgac tgggacagga
    24121 gcgattccac acccaatgcc tcgacccggt gccggctgtc actcagcaca aggtcaaggg
    24181 ccagcagaat cgtgcttttc ccggactcat tgtccccgac cagaatgtta cggtcatgag
    24241 tgaagcgcag gtccagttcc ggaaactttt taaagttttg cagcataagc cgcgtgatca
    24301 gaggcatctt ttattccttt atataccgct gactgaaaga gtgtccggct gcgccagacc
    24361 gcctgttttg ttttacagcg ttatcttacc cagtcttcca gcacaagacc cggtacccgc
    24421 tcaaattccc gcgtattatt cgtcaccagc acggcaccgg cggcgatggc gtgcccggca
    24481 atggccgtgt cgttcgggcc gatcggcgtc ccggccattc gcagcgccac cttaatctcc
    24541 gtggtggcgt ccaccgcagc gcgatcccag ggcaggatgg catcgaggcg ggcgcagaac
    24601 gcgtcgacca gctcgacgtg gcgcggggag gccttcgggc cggtggcccc gaagcgcatt
    24661 tcagaataag tgatggccga gacaacgatg cgctggccgc gcagcaccgc ctgctccagg
    24721 cgcttcagga cggcttccgg ctgctcgcgc atgatgaacg agcagataca ggtgtcgagc
    24781 atataggtct tgttcacagg ttaaatcgtc cttcgtcgct gacaacgtcc tcgcgctccg
    24841 ccataaagtc cgggtctgcc ttctcgaact gcgcgaacga gccccaggtc ggccggacgg
    24901 gacgcaaaat aatgctgtcc ccttcccgga cgatctccag ctcgctcact ccctcaaaat
    24961 ccagatcgcg gggcagacga atggcgcggt tattgccgtt tttaaaaatg gatacagttc
    25021 tcatcatttc ctcctggccg accggcctgt atgactatgt tcagtatatg cagatgcaaa
    25081 gcatatgtat agtcatagca tatgcagatg gtaagtatat gcgtatgcca cacctatgca
    25141 gatgcccggc atatggatat gttgaaccta tgttgtattc tctcttttcc cggtcagatc
    25201 cgaaaaaagg tagttccgga tctgattcag ccccgccggc gcgcagcggc ccggaaacac
    25261 aagatgtagc ggtgtttcca gctgtcagtg accatatatg ttgtgcccct cccctgcccc
    25321 gtgaccggcc gctcaccacc ctgaaagggc gctgtggtta ttccctgacc gtggtacact
    25381 tccggaaact tcgtaaagcg cgaaaagtcg gatccggcca gagcggccgt caggtaattt
    25441 aattacgttg ttatatggct gcttattatt ttagtatgtg aaaatcactc tcgtgaaagt
    25501 cactgtcgcg acagagtggc actcatctga cgatgattga ggtgtggtaa aattgcacgg
    25561 ctaactattc aactgaggaa aggacatgtt tactgcattc aatgagagaa atgatttcag
    25621 ttatgctttt gaaaaaatcc gtaatgcgat ttccgcgcca ggagaaaata atctttatgc
    25681 tgcaacagaa ttaggtcttg gcattctgct ccgtaaatac gagcagtttc gccaggaact
    25741 ggatgcggcc ggtgagctgg gaaactggga atatgatctc gatacctaca atcactgtat
    25801 tgcggtgctg caacgttact tcaccggcaa tccatccgga ctgacagaac gtgatgcccg
    25861 gatttacagc cattacctgc agactgagca caaaaggttt gtgaaactgg ctgaagagct
    25921 ggctgccggc cgctgactac ggacagaggg cgggatttct caggaatata aaggggtaaa
    25981 tgatcaatga ctgatataca ggccgcaact gagagtatag ttgctgcgac atcccatccg
    26041 gtttccgtac agctgattaa tcaaggggcg gggatctggg gaaacgtggc aaccgggctt
    26101 atcactggcc tgcttactgg gggtataaca ctcactggca tctggctgac acattatttc
    26161 acgcttaagc gtgagagaca ggcgtcagaa gataaaatga aaaaggaact gcattacatt
    26221 gccaccgagt tggtattcat gcttgaacgg tatgctgagg gttgtttccg ggttgtgacg
    26281 gatgacggcc aggatgatga tgccccccag cctgagagaa aagctgtcac gaattaccct
    26341 gaactgaatc tgatcgatgt ctccggtgac tggcggactt tagagccacg tcttatgtat
    26401 cgcatccgtg aactgccggt gctccaggat gaggcccaca gggcaattgc atatgccgcc
    26461 gaatactccg accctccttg gcataaggac tatttcaggg aacggcagta tcagttcacg
    26521 cgcttgggca tcaacgctgt cattcttgcc gtccgtctgc gcaaggcaac cgggatgccc
    26581 gaaacacgtc ttacaggtca tgatgaatgg tctgcagttt ccgtgtttcg taaagtctgg
    26641 aggcgcgaaa gagccctgcg cgctgctgaa gctacccgca acagggagtg gaatcaatta
    26701 gtgatacctg atggaatgtc aaaccaatga gcggcctctt atcatattct cacccgcagc
    26761 agccggcgca aatgccggtg gccattgact atcccgccgc gctggccctg cgccagatgg
    26821 cgctcgttca agatgaacta ccgaaatacc tgctggcacc ggaagtcagc gccctgctcc
    26881 attatgtgcc cgatttgcac cgcaagatgc tgctggcaac cctctggaac accggcgcac
    26941 gtatcaacga ggcgctggcg ctgacccggg gggatttttc gctggtgcca ccgtatccgt
    27001 tcgtgcagct ggccacgctt aagcagcgca ccgaaaaagc ggccaggaca gccggccgag
    27061 ctcccgccgg tagccaggct catcgtctgg ttccgctttc cgatcaccac tacgtcagcc
    27121 agctgcagat gatggtggcc accctgaaaa ttccgctgga aagacgcaac aagcgtaccg
    27181 gcagaacaga gaaagcccgc atctgggaca tcaccgaccg gacagtacgg acctggattg
    27241 gcgaagcggt tgaagcggcc gccgtcgacg gggtgacatt ctcggtgccg gtcaccccgc
    27301 atacgttccg ccactcctac gcgatgcata tgctgtatgc cggcatacca ctgaaggttt
    27361 tgcagagcct gatgggccac aaatcgatta gctcgacgga agtctatacg aaggtgttcg
    27421 cacttgatgt tgctgcgcgg catcgagttc agtttcagat gcccgaagcg gatgcggtag
    27481 ccatgctgaa agggaatatt taagtactta ggagaatgat gctggcgaac gtcctgctcg
    27541 ccggggaggt ctgtcagacg ttatctggac cagctgacgg gaatatctgc tctgtattcc
    27601 tcatactgct catagatcgc atgctgaagc atcgtaatac gttctgacaa cctgttggcg
    27661 tccgacatat gccgccattc cccctcaata gtggttttct gtccatccgg gagattgagc
    27721 gtgatcaata cctttgtatc acgaataatc accccgtcag tgaaagaatt aagaccactc
    27781 cttacggtat tatctatctg tatagtttca agtttcatct tgttacctcc tgttgaccgg
    27841 atcccaagca tagatatctg aattcaaatt gcctagtgaa atgtctggat atgccgcatt
    27901 tttcccctta tacagcgaag ctggccaaag gccagcccgc ttggatttat cgcttttgcc
    27961 agtagatcag catggcaagg aacaggattg ttgccccctg agaagcggtc aggaaagttt
    28021 ccagcaatga cattatcgta aaactccgca ttattaattt caggtgtgtg attcaggggc
    28081 cttagtcccc cttttacagg acgtagtgtt ctgtcacgac ggaagccagg gttaataaaa
    28141 acgattcgaa tatgtctgca gggacgatag aaatcttcgt gcgggttgtc tcgctgtagc
    28201 cggctctgga gagcgactcg ggggaggagt agtatcttcc ggccacggat atgatcgagc
    28261 cagcagtgct cgccgcagtc gagcgacagg gcgaagcccc gagtgagcga ggaagcacca
    28321 gggaacaaaa cttataaatt ctgcttacgc tcaatgcctg aaaaatcacc tctcctcggg
    28381 gttatccact tatccacggg catattttta taaagtactt ttttattctt tttctttatt
    28441 ttacatcttt tagggagcct gaaagccgcg tacagtgcgg cctgagaggg ggcctgtatg
    28501 ggcaactggt aaacataata tgggaaatta atcacgtatc agtgggtttt gtgtcaacaa
    28561 gctatgggat acgcatcaac aagctatggg aaagaggtca agttcagttc tcaattatcc
    28621 acttgtggat aaagtgcaga tttttccggt ggataagtat cgcgatagct tgcaatttct
    28681 gttttcactg tcattatggg tgggtaaaaa tttacccata ggcattgaa
//
