LOCUS       CP067707                7837 bp    DNA     circular BCT 02-MAR-2022
DEFINITION  Klebsiella pneumoniae strain ARLG-4851 plasmid pC349_4, complete
            sequence.
ACCESSION   CP067707
VERSION     CP067707.1
DBLINK      BioProject: PRJNA658369
            BioSample: SAMN15869026
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 7837)
  AUTHORS   Shropshire,W.C.
  TITLE     Highly Conserved and Distinct Accessory Genomes Drive Independent
            and Parallel Endemic Spread of Carbapenem-Resistant Klebsiella
            pneumoniae Clonal Groups 258 and 307
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7837)
  AUTHORS   Shropshire,W.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) HMH-CDI, Hackensack-Meridian Health Center
            for Discovery and Innovation, 340 Kingsland Street, Building 102,
            Nutley, NJ 07110, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Flye v. 2.7
            Assembly Name                     :: C349
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 179x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 01/11/2021 15:37:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.0
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,554
            CDSs (total)                      :: 5,431
            Genes (coding)                    :: 5,334
            CDSs (with protein)               :: 5,334
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 40 of 97
            Pseudo Genes (incomplete)         :: 56 of 97
            Pseudo Genes (internal stop)      :: 17 of 97
            Pseudo Genes (multiple problems)  :: 14 of 97
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7837
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ARLG-4851"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pC349_4"
                     /geo_loc_name="USA: South"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..192
                     /locus_tag="JJ503_27705"
     CDS             1..192
                     /locus_tag="JJ503_27705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UMG38663.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            192..593
                     /locus_tag="JJ503_27710"
     CDS             192..593
                     /locus_tag="JJ503_27710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="UMG38664.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSGQRDTASADQSEQVIRHLKQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(953..3850)
                     /locus_tag="JJ503_27715"
     CDS             complement(953..3850)
                     /locus_tag="JJ503_27715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="UMG38665.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            3945..4550
                     /locus_tag="JJ503_27720"
     CDS             3945..4550
                     /locus_tag="JJ503_27720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UMG38659.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            complement(4609..4851)
                     /locus_tag="JJ503_27725"
     CDS             complement(4609..4851)
                     /locus_tag="JJ503_27725"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMG38660.1"
                     /translation="MHSAEIHTIQPGEVLFPAFFSSENGERGRNLLRGREALPAQPENR
                     FSAPSGIGFVDGRQSRYGKSPDDSPHDSPAIRIVN"
                     /name="hypothetical protein"
     gene            complement(5217..5849)
                     /locus_tag="JJ503_27730"
     CDS             complement(5217..5849)
                     /locus_tag="JJ503_27730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMG38661.1"
                     /translation="MKDINNSKKIIFVEGDDDFHFLCNLLEIQGITDVFVEKINGKSKL
                     KQALRAFKNIDSFDEKESIFIILDADTSFSDTERSIIATLRELQISSPSSHNEIAMNGN
                     TKISFFIMPGKDKQGAIEDLIIEHASTRALYEYIIEFFEKIKNNKDDISASDKEYTYPT
                     NEKKAKVQVYLSCNRESDSRIGISMKNGIINTADNCFDEIKDFISKI"
                     /name="hypothetical protein"
     gene            complement(5849..6964)
                     /locus_tag="JJ503_27735"
     CDS             complement(5849..6964)
                     /locus_tag="JJ503_27735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019405083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="UMG38662.1"
                     /translation="MIKEISLKNFKCFNELYLKQLKTLNIIAGKNNYGKTSILDAIFCF
                     YDVKNPAVLLNIQAFRKEMAEINKNKPFWVSYFHDMDTSQKMSIVIRDERSEVTQTYET
                     ETNQRLESSLSLNVDTVLSNQNIPRQTIGSQATVNSLKINVTETPNAKNRVSNKLFSMQ
                     LKEDGVEIKSEIKNERDGINYKFKTATIITTSRKINKEATITNVSSLLTQKRKKDILEN
                     LKKIDDRIVDIAISAIGNNKEIYLDIGFSELNEISMLGEGISRALSFISSVLVQENSII
                     LIDEIENGIHYSVIKDIIKSLISSAKQNNNQIFATTHSQDVIRAINEIDSKNEDIAYIR
                     LGREKNSLKPTAVQFNMDDFSYSVENDWEVR"
                     /name="AAA family ATPase"
     gene            complement(7309..7422)
                     /locus_tag="JJ503_27740"
                     /pseudo=""
     CDS             complement(7309..7422)
                     /locus_tag="JJ503_27740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     Typing          complement(7310..7717)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.399"
                     /coverage="99.0"
                     /evalue="5.92e-171"
ORIGIN
        1 atgacgaaac aacagaaaac agcgctgaac atggctaaat tcatccagaa tcagtctctg
       61 ctcctgctgg agaagcttaa cgagcttgat ctcgatgtcg aggccgacct ttgtgagaaa
      121 ctccacgatg atgcggagca tcttttccgt acactgtcct cgagactgga tgcattacag
      181 gatggtaact gatggccaga gtgtctatta gtgaggctgc ccgactgacg ggtaagagta
      241 gaacaacact gcacaggtta attaaagcag gtgacctgtc cacctgtagc ggtgagcgca
      301 atgcaaaaat ggtagatact tcagagcttt tacgtgtctt tggccccttt gagcaaccga
      361 agggtgaaca ccattctgga caggtctctg gacagcgtga tacagcctct gctgaccaga
      421 gtgaacaggt gatccgtcat ctgaaacagg agattgaaca cctgaacacc ttacttttgt
      481 ccaaggattc gcacattgac agcctgaaac aggccatgct ccttcttgaa aatcaccagg
      541 caaaattaac tgaatccccg gcgccatggt ggaaattctg gaaaaaatcc tgaccccgtc
      601 atgcttcagt tttcctctcc ggccatccca gggagttcct gaaccttccc aaaaatcgtc
      661 agatctctga acgctcctca ccactaaaaa tacccacacc ccacgcaaaa ttaaaatttt
      721 gcagattcct tatttacaac aatgggttaa tgaaaaataa atgtgcggtg atgtgttaca
      781 aagtgcagat ccaagtcgtg gacgactcta tggcgaatcg ctgacgaatt gcccacgatt
      841 catatgtgaa tcacgcttta ttatcatatt gttatgatga atcgactctt gattcaattc
      901 atcactttgg gtgttttttg gggtcggttc cggctgaggg cgaaatgaca ccctaagctt
      961 tcggttcctt gggccaaaga tattcgccag tcagtagaat gtgcgcccag cccaatgggg
     1021 atatgtgggg aagaaattca gggggaacat ccaacccttc gttccgccgc tccgtgacgg
     1081 catgaccaag atggacggta ttccagtaaa tgatcaccgc agtcaataaa ttgagcccag
     1141 cgattcggta gtgctgcccc tctgtcgtgc gatcgcgaat ttccccctgc ctcccgatac
     1201 ggagcgcatt tttgagcgca tggtgggcct ctcccttgtt aagaccgatc tgagcacgcc
     1261 gctgcatgtc cgtatccagg atccactcaa taatgaaaag ggtccgttca atacgaccaa
     1321 cttcacgaag cgcaactgca aggttgtttt gtcgtgggta agaagcgagc ttgcgcagga
     1381 gttggctggg cctgattttg ccagcggtca tcgtcgcggc acaacggaaa atatcaggcc
     1441 agttcgcaac gataagatcc tcccgggctt ttccacctac caacttgcgt aactccctgg
     1501 gggtcgtatc gggattaaat acgtacaacc gcttcgatgg cagatccctg attcgcagaa
     1561 cgagattgta gccgagcagg ctactggctc cgaacaaatg gtcggtgaat cctgctgtat
     1621 cggcatactg ttcgcgaaca tggcgaccga cctcgttcat cagtagtcca tcgagaatat
     1681 acggtgcctc gctcacggtc gccgggatcg actgacaagc gaatggcgcg aactggtcgc
     1741 ttacgtgagt atacgctttg aggccgggaa cagaaccata tttggcattg accatgttca
     1801 tggcttcgcc atgccgcgct gtcgggaaaa actgaccatc gctcgatgct gacgtgccca
     1861 tcccccagac gcgtgacatc ggcagtttac cctgcgcggc caccacaatt gccaatgcct
     1921 ggttcatggc ttcgctttca acatgccagc gggcaaggcg tgagagctgc cagtaatcat
     1981 gcgtgtttgt agcttccgcc atcttacgca ggcccagatt gagcccttca gcgagcagga
     2041 cgttgagcag accgatccgg tcgcgacatg gagccccggt tctcagatgg gtaaacgcat
     2101 ctgtgaaacc aagggctgca tcaacttcaa gcagcatgtc ggtaatccga acggacggca
     2161 ttcggcgata cagatccagt atgagtgcct cggcaccatc cggcacgtct gctgtcaacc
     2221 tgtcgatccg caacgttcca tcttctatgc taccgtgcgg aatagtgccg ttacgggcag
     2281 cccgggccag ccgcttaaga gcgatcgtga gtcgcgcctt tctgtctgcc agccaatcct
     2341 gtgggttgga aggcacggcc agttttgcat tttcctgcgc cgcgatcatc ggcaccagta
     2401 cctgcttgag gtcaccatag cggcgcgaat gagcgagcca gacatctccg gaacgaaaag
     2461 catcccggag gtgaaagagt accgccactt cccaaagacg ggtatctcct ttttcctgag
     2521 ctcgtaaatg acggttccat ttggagctgg gccgcaggaa acgcctttct ggcgatgcaa
     2581 cacctttcat ctctccgatc gacaaagctg ctgctaccaa tggtccggcg accggcgcgg
     2641 cttcgagctt cagacagcgc aacatgcggg gcgcataacg acgaaagcga tggtatccct
     2701 gcccgacata tgcaagaggc tcatcggcta gcgtgttgct gagttgagtc cctgtcgcta
     2761 ccagttgagc gagccggtcc catgcaaccg aactggcgac agccatctcc agcggggttc
     2821 cgtcactgcg ggcctcaagc aacgaagctc ccagcgcggt gaaggtacgg atcgtatccg
     2881 tgagtgtggc tttagagccg gaaattgttt cgtcatgctg gcgcttcgct tcccgccagg
     2941 tttttcctac gatcctgtca tgggtttcga ctatggcatc agcaatcgcc gcttcccact
     3001 ccacaacaca gacggcaagg atcgcccagc ggcggtccga agtgatgtca cgcaaaccgt
     3061 cggtgaagta gcgttcaccc tgccgacgca gccgggcaat gcgatgggca ggtatgctgg
     3121 ccaaagcact atgattgata ttcagggtac gcagaaattc gagcctgtcg agcaaacggt
     3181 tagcagcagc cgagttgtta ccaacctcga agttgcgaag ccagatgaaa cgactgatat
     3241 tgccggcgag catttcactc agaagtttgt ccaggtgatc gcgaacatcc gctgttaaat
     3301 tttccgcaat ccgcgtttca atccgccgct cagcggcgac cagagcatcc gcgcacaagc
     3361 gctcgattgt cgatactgcg ggcagaatgg tggaagtttc ccgacaccgc acaataaaac
     3421 gatgagcaag atcctcgttt gatctggcat cttcggcctg gccgaaagtc cactcccgca
     3481 gatcacgggc accacggccc gtgaaggtct tgtagccgta aatttcgcgc agcgtgtcca
     3541 tgtgctgctg acgggtttgg cgccgtgtgg cataagtgag aagcgcatca gccggaactc
     3601 caagctgagc accgacgaag gaaaggactt cacgcgggat catctcacca ggagccagtg
     3661 cacggcccgg atatcgtaag gcacaaagtt gcagggcaaa gccaatcctg ttttccggtc
     3721 tgcggcgctg cctaatgttt tccaggtcat catcgcccag cgtgtagaac ttcagtagcg
     3781 acagttcgtc cgtgggcaga tcgaacagcg ctgctcgctg ccgttcggtg aaaatatggc
     3841 gtcgtgacat acaaattcgt cccttttgaa gtatagtctg ttttggacaa cagccagccc
     3901 atataaatca gggcgttccg atacaaaaat ccaggagggt tcaattggga catcgtgccg
     3961 ccatttactg ccgggtttca acagcggatc agtcttgtga acgccaggaa tttgatctgc
     4021 gagccttcgc cggccgtgcc ggctacgacg tggtgggaat atttaaggaa acaggttcag
     4081 gaactaaact cgaccgggcc gagcgaaaga aagtcctggc gcttgcccag tccagacaaa
     4141 ttgatgcaat cctggtcact gagctttccc ggtgggggcg ctcgacgctc gatctgctca
     4201 atacgctacg tgaactggag aactggaagg tttccgtgat agccatgaat ggaatggcgt
     4261 tcgatctttc gtcgccgtat ggacgaatgc tggcgacgtt tctttccggc attgcggagt
     4321 ttgagcggga tctcatcagc gagcgggtca agtcaggcct tgctgttgcg aaggcacgtg
     4381 gtaagaggct tggtcgtcag gccggagtgc gaccaaaatc agaccgactt ttgcctaagg
     4441 tggttgcgat gagggccgag ggacgcagct atcgctggat cgcacgcgag ctcggtatca
     4501 gcaagaatac cgtcgctgac atcgtgcaac gacacagagc taacgcttag ggtgtcattt
     4561 cgccctcagc cggaaccgac cccttttttg ctcatggtga ctcttgattc aattcacgat
     4621 tcgaatcgcc ggtgaatcgt gtggtgagtc gtccggcgac ttgccataac gtgattgccg
     4681 gccgtcgacg aacccgattc ctgaaggtgc tgaaaaccgg ttttccggct gcgccggcaa
     4741 cgcttcacgg ccacgcaata aattgcgtcc ccgttcaccg ttttcggagg agaagaacgc
     4801 cggaaacagg acttcccctg gctgaatggt gtgaatttcc gcgctatgca cttgcgcgca
     4861 tactcatgca tgccgtaaaa acagagcctg cgcgtttctg gcgggttttc gggtggtttg
     4921 ttgcctgttt taccggtttc ccgtcagaaa cgtcctgagt ccgttttagc ggtgcgtaca
     4981 attatgattt tatgttaaat tgttttaagt gaatagagag aatataactt aagggagcat
     5041 cttgtgctgg gtcttttaca ttagatctgc acaatcattg ttttggcatc tggtgatgtc
     5101 tttaggacgt ttgagattgc tgataactaa agtgtatgat gctttctata cgttatccgg
     5161 cgtttaataa caccctggtg ataagccagc ccgtgaaggg ctggcttgat ttggatttat
     5221 atttttgaaa taaaatcttt tatttcatca aagcaattgt ctgctgtgtt tattattcca
     5281 tttttcatgg atattcctat tcttgagtcg gattctctat tgcagctaag atagacttgt
     5341 accttagctt ttttttcgtt tgttggataa gtgtactctt tgtcactcgc tgagatgtca
     5401 tctttattat ttttaatttt ttcgaaaaat tctattatgt attcatataa cgctcgagtg
     5461 cttgcgtgtt caattatcag atcttcaatg gcaccttgct tgtcttttcc tggcattata
     5521 aagaaagaaa tttttgtatt gccattcata gctatctcgt tatgcgagct gggggaggag
     5581 atttgtagtt ctcgcaatgt ggcaattatt gatctttctg tgtcagaaaa tgatgtgtca
     5641 gcatctaata taataaaaat actttctttt tcatcgaaag aatcaatgtt tttgaatgct
     5701 ctaagtgctt gttttaattt tgattttcca tttatttttt cgacaaaaac atcggtaatg
     5761 ccttgtattt caagtaggtt gcatagaaaa tgaaaatcat catcaccctc aacgaaaatg
     5821 atctttttgc tattatttat gtctttcatt atcttacctc ccagtcgttc tcaactgagt
     5881 aggagaaatc atccatattg aattgtacgg ctgttggttt tagggagttc ttttctcttc
     5941 ctagtctaat ataagcgata tcttcatttt tgctatctat ttcgtttatt gctcgtatca
     6001 catcttgact atgagttgtt gcaaatattt gattgttgtt ttgttttgca gatgaaatta
     6061 atgattttat tatgtcttta attactgagt aatgtattcc gttctcgatt tcatcaataa
     6121 gaataattga gttttcctgt accagcactg agctgataaa agataatgct cgactgatac
     6181 cctcgccaag cattgatatt tcatttagct cactaaatcc aatgtctaaa tatatttcct
     6241 tattgttacc tatcgcagat attgctatat ctacaattct gtcatctatt ttttttaagt
     6301 tttctagtat gtcttttttc cttttttgtg ttagtaggct agatacattt gtaattgttg
     6361 cctctttgtt tatctttctg gatgttgtta ttattgttgc tgtcttaaat ttataattaa
     6421 tcccatccct ttcgtttttt atttcggatt ttatttctac gccatcttct ttcaattgca
     6481 tagagaaaag cttattggaa accctgtttt tcgcattggg tgtctcggtc acatttattt
     6541 ttaaagagtt tactgtggcc tgagaaccga tagtttgacg aggtatgttt tggttagata
     6601 gtacggtgtc aacgtttaga gacaaacttg attctaatct ctgatttgtt tctgtttcat
     6661 atgtttgtgt tacttcagag cgttcatctc gaatgactat ggacatcttt tgtgatgtgt
     6721 ccatatcatg aaagtaacta acccaaaatg gcttgttttt gtttatttct gccatttctt
     6781 ttctgaatgc ttgaatgttt aacaaaacag ccgggttttt tacatcataa aaacaaaaaa
     6841 tagcatccag tatagatgtt ttcccgtagt tgtttttccc agctatgata tttaaagtct
     6901 ttaattgctt tagatatagc tcattgaagc atttgaagtt ctttaaactt atttccttta
     6961 tcatgatagc ctctgttcgt gtttttgtta tatgccatac gatttgttag taccttaata
     7021 aaatgtacag ctttcattgt gattagctag actttatgtc aaagattaac tttgattgct
     7081 tgtgttttaa tcgatttttt ttactttctt cttgagatta tctggcagca gccgtaagct
     7141 tccggctgtg aacgaaaaaa accgccttgg cgggcggttt tttcgaaagg ttcagtagag
     7201 ttggcgctct atgaaccgag gtaactggct taaagggagc gcagtcacca aaactgttcg
     7261 tttagtttag ctttaactgg cgtataactt caagactaac tccctaaatc agttaccagt
     7321 ggctgctgcc agtggcgctt tgtcgtgtct ttccgggttg gactcaagac gatagttacc
     7381 ggattaggcg cagcagtcgg actgaacggg gggttcgtgc atacagtcca gcttggagcg
     7441 aactgcctac ccggaactga gtgtcaggcg tggaatgaga caaacgcggc cataacagcg
     7501 gaatgacacc ggtaaaccga aaggcaggaa caggagagcg cacgagggag ccatcagggg
     7561 gaaacgcctg gtatctttat agtcctgtcg ggtttcgcca ccactgattt gagcgtcaga
     7621 ttccgtgatg ctcgtcaggg gggcggagcc tatggaaaaa cggccgctgt gcggcctttc
     7681 cttctttcct ccatgcgatt actcggtttt ctcgagcgtt tctacgcatg ctcctgccgc
     7741 tcgccgcagc cgaacggcag gagcgtagcg actgagtgag cgaggaagcg gaaaagagga
     7801 gatccctaca ctgaccactg acgctctgag gcctctt
//
