LOCUS       CP067674               21579 bp    DNA     circular BCT 01-MAR-2022
DEFINITION  Klebsiella pneumoniae strain ARLG-3489 plasmid pC4694_3, complete
            sequence.
ACCESSION   CP067674
VERSION     CP067674.1
DBLINK      BioProject: PRJNA658369
            BioSample: SAMN15868159
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 21579)
  AUTHORS   Shropshire,W.C.
  TITLE     Highly Conserved and Distinct Accessory Genomes Drive Independent
            and Parallel Endemic Spread of Carbapenem-Resistant Klebsiella
            pneumoniae Clonal Groups 258 and 307
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21579)
  AUTHORS   Shropshire,W.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) HMH-CDI, Hackensack-Meridian Health Center
            for Discovery and Innovation, 340 Kingsland Street, Building 102,
            Nutley, NJ 07110, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Flye v. 2.7
            Assembly Name                     :: C4694
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 348x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 01/11/2021 15:25:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.0
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,418
            CDSs (total)                      :: 5,294
            Genes (coding)                    :: 5,206
            CDSs (with protein)               :: 5,206
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 40 of 88
            Pseudo Genes (internal stop)      :: 18 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..21579
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ARLG-3489"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pC4694_3"
                     /geo_loc_name="USA: South"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..180
                     /locus_tag="JJW41_26980"
     CDS             1..180
                     /locus_tag="JJW41_26980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UMF31913.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(208..738)
                     /locus_tag="JJW41_26985"
     CDS             complement(208..738)
                     /locus_tag="JJW41_26985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMF31914.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(745..1476)
                     /locus_tag="JJW41_26990"
     CDS             complement(745..1476)
                     /locus_tag="JJW41_26990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-relaxation family protein"
                     /protein_id="UMF31915.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="replication-relaxation family protein"
     gene            complement(1476..3440)
                     /locus_tag="JJW41_26995"
     CDS             complement(1476..3440)
                     /locus_tag="JJW41_26995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="UMF31916.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(4921..5070)
                     /locus_tag="JJW41_27000"
     CDS             complement(4921..5070)
                     /locus_tag="JJW41_27000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="UMF31917.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(5155..5412)
                     /locus_tag="JJW41_27005"
     CDS             complement(5155..5412)
                     /locus_tag="JJW41_27005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="UMF31918.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(5422..6243)
                     /locus_tag="JJW41_27010"
     CDS             complement(5422..6243)
                     /locus_tag="JJW41_27010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytotoxic family protein"
                     /protein_id="UMF31919.1"
                     /translation="MSFRSTERQTPTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDK
                     AKAELDAEDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEY
                     GSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKD
                     AENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYG
                     DKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="cytotoxic family protein"
     gene            complement(6359..6529)
                     /locus_tag="JJW41_27015"
                     /pseudo=""
     CDS             complement(6359..6529)
                     /locus_tag="JJW41_27015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            complement(6584..7288)
                     /locus_tag="JJW41_27020"
     CDS             complement(6584..7288)
                     /locus_tag="JJW41_27020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UMF31920.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(7348..7569)
                     /locus_tag="JJW41_27025"
                     /pseudo=""
     CDS             complement(7348..7569)
                     /locus_tag="JJW41_27025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206318.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(7639..8193)
                     /locus_tag="JJW41_27030"
     CDS             complement(7639..8193)
                     /locus_tag="JJW41_27030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /protein_id="UMF31923.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLAD
                     VQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQLLA
                     NASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTP
                     DGPAVYMVQTRQAFERTRSVA"
                     /name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
     gene            complement(8427..8984)
                     /locus_tag="JJW41_27035"
     CDS             complement(8427..8984)
                     /locus_tag="JJW41_27035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UMF31921.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            9148..10047
                     /locus_tag="JJW41_27040"
                     /pseudo=""
     CDS             9148..10047
                     /locus_tag="JJW41_27040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            complement(10099..11814)
                     /gene="tnpR"
                     /locus_tag="JJW41_27045"
     CDS             complement(10099..11814)
                     /gene="tnpR"
                     /locus_tag="JJW41_27045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="UMF31922.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            11924..14953
                     /gene="tnpA"
                     /locus_tag="JJW41_27050"
     CDS             11924..14953
                     /gene="tnpA"
                     /locus_tag="JJW41_27050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="UMF31905.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFEPKAITKHER
                     YTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPGY
                     TTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFGW
                     RQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQL
                     YLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLLS
                     LYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRMR
                     RHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPYL
                     LTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDVL
                     AKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKSE
                     NEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIAQ
                     AMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLET
                     LYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHHV
                     FDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDPA
                     QYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRAI
                     FEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIEI
                     EISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHYT
                     FQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     gene            15060..16085
                     /gene="istA"
                     /locus_tag="JJW41_27055"
     CDS             15060..16085
                     /gene="istA"
                     /locus_tag="JJW41_27055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="UMF31906.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            16082..16861
                     /gene="istB"
                     /locus_tag="JJW41_27060"
     CDS             16082..16861
                     /gene="istB"
                     /locus_tag="JJW41_27060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="UMF31907.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            17248..18129
                     /locus_tag="JJW41_27065"
     CDS             17248..18129
                     /locus_tag="JJW41_27065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /protein_id="UMF31908.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKYSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-3"
     gene            complement(18379..19698)
                     /locus_tag="JJW41_27070"
     CDS             complement(18379..19698)
                     /locus_tag="JJW41_27070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /protein_id="UMF31909.1"
                     /translation="MAASYLPYRPDQSYLLPPSLGEWLPEGHLAYFISETVDTLDLSAF
                     HARYAGGGPGNQPFHPAMMVKVLIYGYASGVFSSRKLARKLYEDVALRVLAAGNFPAHR
                     TLSDFRALHLTELENLFVQVVQLARECGLVKLGTIAVDGTKVKANASRHKAMSYKRMKP
                     AEDELHCEIKALLDRAKATDDQERNEPELDIPAEISRREKRLEAIQAAKARLEARQREA
                     DQARGRSEDDGRRPRHPDGSDKGGGSYKREFGVPDDRDQESFTDPDSRIMKHAGGGSEQ
                     SYNGYTAVDAEHQIIVAAELTNCAADSQALLGMLAAVQANTGEMPAQTLADAGFRSEAV
                     LAKVADHHGDVIVALGREGREDAKVNAKTHPHTAAIAAKLKTEQGDAAYRRRKSIVEAP
                     NGWIKAVMGLRQFSMRGLDKVQAEWKLVCMALNLRRMAYL"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            20053..20214
                     /locus_tag="JJW41_27075"
                     /pseudo=""
     CDS             20053..20214
                     /locus_tag="JJW41_27075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            20520..20783
                     /locus_tag="JJW41_27080"
     CDS             20520..20783
                     /locus_tag="JJW41_27080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="UMF31910.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="plasmid stabilization protein"
     gene            20773..21072
                     /locus_tag="JJW41_27085"
     CDS             20773..21072
                     /locus_tag="JJW41_27085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="UMF31911.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(21134..21511)
                     /locus_tag="JJW41_27090"
     CDS             complement(21134..21511)
                     /locus_tag="JJW41_27090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="UMF31912.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="entry exclusion protein 1"
     ARG             17249..18126
                     /name="blaKPC-3"
                     /gene="blaKPC-3"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7643..8193)
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7301..7557)
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             complement(7640..8244)
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          4240..4818
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(749..1476)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
ORIGIN
        1 atgacaaaac aggaaaaaac agccctcaat atggctaaat ttattaagga gcagtcgctg
       61 ctattgctcg ataaactgaa tgagctggat atggataccc cggccgacat gtgcgagcgg
      121 ctacacgagg atgcggaaac actctggcag gtgatgcggg ataagctcgg ggaggaataa
      181 cagcaccggc atggccggtg ctggcattta ttttttgccg aacggccacc accggcgggc
      241 aggtttgtcc tccggcagtt caggtaccgg cacgttaaaa tagcggctgt tatattcccg
      301 catcagctcc gctttcagct tctcgttcac cgcgctttcc ccgtgccgct cactcaccac
      361 gtcaatcatc gcgttaatct gctccggtga gcacttcccg gcatcaacca cctgcacacc
      421 gttctcgatg gcgaaccgct ccaccttgcg atagaggtaa tcacacagct tcattcctgt
      481 gggtttgttc cgttcccatt gcggattttt accagtgaaa aagtacgtgg ctttttcgtc
      541 gctgttgagc cgctcgtcat acatcccgat ggatttcatc atcgccagat gctgggcccg
      601 gtcgacaaaa cagaaaacat acgccccggt ctgccaggcg agcaccacca tatcttccag
      661 atgctcgctg gtcggcatga tgcagcgctc gccgttccgg tcctccgcgt cttcaataaa
      721 taccatgtac agcgccataa tccctcactc cgttgtcata aatttaaagc acgcaaacaa
      781 ccgttcacga tccagctctg ccgttttgcg ggcctcgccg gtctgtgggt tcacgatttc
      841 atccaccgac aggattgccc gctgcaccct gacctgcgtc gcccggtccg ggcagatgta
      901 ccagatttca tcgatgccgt tagctttgcg gttgaacaga tacccggaca ccacttcctg
      961 ataccggcga cggctcttga cggtgcgctc cacctcaaac gccaccgttt taccgtccag
     1021 ctccgccagg gcgtccggca ctttcatgcc tttaagactc agacggtgca gaatgcgcca
     1081 gccggtggcc cctctggctt ccatatcaag gcgcagggat tgcacggcca gccggtgcgg
     1141 cagatgtgct gccgacaccc ttgacggctg aaacggaata acatccgcca gcggttcgtc
     1201 ctcgtcgaac gagaacgcca cgccatgcgg cgtcagcccc cacacgctga cctgacggcc
     1261 gtccaccgga tatttggtcc ggaccagcag ccctttcgcc accaggctgt cgaggaagcg
     1321 gtagaccggc tgcaccgccg caatccccag ccgccgcgca accagctccg ccgtggaaca
     1381 cagctcttcc cgcaaccagc gcagggtcag ccgggttttc tccgcgttcc gcgcctgtcg
     1441 tttcgcgtgg ctgacgttgt acagctccag cgccatcagt aaatccccgc aaaatcatca
     1501 tccgctttcg gcccgccgcc gtcggccggg ggccggaact ccgccagggg atcggttttc
     1561 gccagcaccg ggaaacgctg caacgggatt tcccggcgct caacccgcag cggactgctg
     1621 aacgccatcc gggccacacc cagcccggtc atgaccgcga acccgtccgg caggtgttgc
     1681 agggtgttca cgtcaaacag cggccgcgcc tccttctgga tgaagctgtc cccgctgata
     1741 tgctccacgt tccccgcctc ccggctggca cggcggcgct ccacgtccac cctgatttcc
     1801 ccggtctgcc ccgccgccca ctgcgcggac tccaggctgg ccgcccggta aaaccagcgg
     1861 atcggcgtgt tatccagtac cgtggttttc acaaattcag cgggcagatc ctgcccgcac
     1921 tgcccgaaat cgcccagcga ctggtgcgcg agcaacagat tgcagtcccg gctgcgcagc
     1981 gtccccagtg cgttcagtac atacttcgac agcagatatt taatttcatc gagcatcacg
     2041 ctgacgtgtg gccactcccg gaactcgtcc cgcgcaatga tgatttgcgc gcagcgggca
     2101 aacagcattt tttgcacacg gatcaccgcc tcgtcgtcca tcgagccgat aacgtacagg
     2161 cagccgccgc cgttgataat ccccgccaca tcgatgccac tgtccgtctg caggacgctc
     2221 aggtcagcga cgttttccag cctagtgatc aaccccttca cgtccttttt cagggcctcc
     2281 ggcagcgcgt acgccgccgc cagcacctgc tgaatgtttg ccccctgcgg aaactgctcc
     2341 gcaatcagct tcgccgcttt ctgctcgctg atgcggtagt ggtccgccac gtcgccggtc
     2401 tcgcccaggt taagcccggc aatcagcagg tttttcagcg cgtactggtc gagatcgcgg
     2461 aacagattca gctgcgccgg tttccccggc cgcagatcca gcagggtgaa gtccggacag
     2521 tgcgcccgga agacgtgcgg cgcccatgcg tcccctttgg ggtcgaagta caccaccgcg
     2581 tccccgaaat cgcgtacgca gcgaatgagc gcgttggtgg ccatcacgct cttgccgctc
     2641 ccgggcaggc cgaggatctg aatgttggtc ttgcgccagg tatcacgcgg aaccagcacc
     2701 ggcttgccct gctcatcctt acccagaaac accgcctgct cctgccgggc ctgctccgag
     2761 gaaaaatcgg ccagcgcatt aaccggtacc ggctccccga aatgcaggtg gcgcacgtcg
     2821 gtcatctctc ctgtccgctg gctgctgcgc cggctctcct gattcagttt cgcgttcacc
     2881 gcctcgtcag cagccgcaaa atgaccgtca agcagcagga acgccagcag ccgcgccaac
     2941 acaatcccga cagccagccc gcccgcgcac caggcaatcc cgaacaggtt agccggctgc
     3001 agcaggtaat aatctgcgtt tgcgtagagg tccggacgca ggacggtttc tccccagctc
     3061 tcgataaaca cggcgacaac cagccccccc agaagggcca gaccggccgc gccggtcagc
     3121 cagtacgcgt agttccagac atgtcgacgt gccctgacca tccgcccggg cgaatccagc
     3181 gaggccagca ccgaaaatgg cgctggccgt ttattatcgc gcttatagcg atcggcatac
     3241 tcccgtcgct ccttatgact cagccccaca aaacgcatcc gtccggccca aagttcagcc
     3301 agaccgaaaa acaggccgat aactaggaaa gccccggcca gaccgtaata ctcctggtac
     3361 agccagctga cccacggata aatctgccgg gccagctccg gaatgtgcca cttccaggca
     3421 agcgaatccg tattaaacat gttctctctc cttcagacga tggtttgccg gcgtgatgtg
     3481 cagcccccgc tgcacaagcc gcggacatgc cccaaggcat ggcggcggcg gtcacgtccg
     3541 tggtgattgc gttcagcttt caccacggag gccagcctct ttccgcccca tgcggaaaag
     3601 gcgcagcccc ggaggaacaa cgagcacgcc ccagcgtgtg agaggaaaag gcggcacccc
     3661 agtgcggtct tttccggtgt tccggccccc gtcagagttc gccatagcga gcggctgacc
     3721 acccgcaaaa tcaggagcag ctttgctgct tcgccaggtg cgtccagcac cgtggatttt
     3781 tgtgggtggt caggcgtgag cctgacgggg gccgggtgaa tttctggcgt ggccggcgtc
     3841 cagccggacg gagccagaaa gagggggaga gaccgtgcgt cggtggcgtc cagccagcgt
     3901 aagcagggga tatccccctg aggtcagcca cgccctcgcg gggatgacct gtatttctcc
     3961 gtaaggagaa aaaagcaaca gagataggtt aacgtaaaat gttcagcgaa aaaccgatat
     4021 gattcaccta tcctggtaat ttattatcag ggaatataaa gacttaatca ggggacaata
     4081 tgccacatca gcgcgtccgg tgtccgtctt gtaggtgccg gggaaattgc gcctcctcgc
     4141 tcactcggtc gctacgctcc ggccgtgaga ctgcggcggg cgctgcggac acatgcaaag
     4201 ttacccacag attccgtgaa taagcagggg actaacatgt gaggcaaaac ggcaaggcca
     4261 cgcaggtggc gtttttccat aggctccgcc ctcctgactg agttcacata aacagacgct
     4321 ttttcggtgc atctgtggga gccggtggct caaccatgaa tcagtcagga gtggcgaaac
     4381 ccgacaggac ttaaagatca tcaccgtttc cgatgaatcg ctccctcttg cgctctcctg
     4441 ttccaaccct gccgtttccc ggatacctgt tccgcctttc tcccttgcgg gaagtgtggc
     4501 gctttctcat agctcacact ctggtatctc ggctcggtgt aggtcgttcg ctccaagctg
     4561 ggctgtaagc aagaaccccc cgttcagccc gactgctgcg ccttatccgg taactgttca
     4621 cttgagtcca acccggaaaa gcacgcaaaa cgccactggc agcagccatt ggtaactggg
     4681 agttcgcaga ggatttgttt agctaaacac gcggttgctc ttgaagtgtg cgccaaagtc
     4741 cggctacact ggaaggacag atttggttgc tgtgctctgc gaaagccagt taccacggtt
     4801 aagcagttcc ccaactgact taaccttcga tcaaaccacc tccccaggtg gttttttcgt
     4861 ttacagggca aaagattacg cgcagaaaaa aaggatctca agaagatcct ttgatctttt
     4921 ctactgaacc gcgatccccg tcagttcaga ggaggacgat ggtgccaccg ttccaccctg
     4981 aacatcccgg atatagtttg cctgacatgc gaccagaaga aagcctgaaa aaatcaatat
     5041 aaaaagaaaa acaaccttta cctttttcat ataccttccc tgtatttaaa aaccccggta
     5101 ttcatccctg aacaccggaa gtctgtattt caaatcatcc ttgataactt ttgcttacca
     5161 gttaccatcc cggtaaacaa aggatacaaa gtaatcaaat ttactaatat cgattacatt
     5221 tttaaagtgt ggctgtaata tcgaaaccca tgatttttca acatcaaacc aaccattatt
     5281 aatattatcc tttaaaggca tccccagact ttcaatgaca gaaccatcat caccgaagtc
     5341 ttttgagtat tcaccacctt taaactcttc ggttttctta tcaaaccaat gaatatgtaa
     5401 tttaagcccc atatttacct cttaaagata ttttttaatg tttcgttttg gatccggccc
     5461 tttaacctgc ttacccgttt ttggatcgaa tgccccgagg tgttcgccat cactggcgcg
     5521 gtacccttca agctcaccgt gctgggaatc ccattcataa attttacgct ttttatcacc
     5581 ataccatcgg gcccgcttac caccaccacc ttgtttaggg gttttaggtt taccctcttt
     5641 caactctccc aaccccttaa tatcttcagt cttgggatca ggaaaataat catggccgta
     5701 atctttagtt cccttacgag gttttttctt ttcctcattt aatttatttt ctgcatcctt
     5761 cgcttttttc tccttttgtt tccggctctc catcgccccg gaaagcgcag ccttatccct
     5821 ggataaggat tcattcattt cgtttaaaga tgtctgggca gcttttaatt tctcattctg
     5881 attctgaata tccttatcaa gatagcgaac ctgatcctgc cacccggagc catattcatg
     5941 aggcgggtta taagtcacaa aatcatcttt atttgcctct gcctctttta cctttttatc
     6001 ggcttcctga acagcagccc ttgcaccggg gatcgccttc tctgtcgatg caatgcgact
     6061 gtttaaggtc gcaatatttt tatcttcagc atccagctca gctttcgctt tatcatactc
     6121 tcttttcagc ccctcttccg ggtgagcagc gtcccatgcc tgctggcgac gcttttcttc
     6181 ctccagacgc tgttttacct gtgccggagt aggggtctga cgctcagtgg aacgaaaact
     6241 cacgttaagg gattttggtc atgagattat caaaaaggat cttcacctag atccttttaa
     6301 attaaaaatg aagttttaaa tcaatctaaa gtatatatga gtaaacttgg tctgacagtt
     6361 accaatgctt aatcagtgag gcacctatct cagcgatctg tctatttcgt tcatccatag
     6421 ttgcctgact ccccgtcgtg tagataacta cgatacggga gggcttacca tctggcccca
     6481 gtgctgcaat gataccgcga gacccacgct caccggctcc agatttatca gggcactgtt
     6541 gcaaagttag cgatgaggca gccttttgtc ttattcaaag gccttacatt tcaaaaactc
     6601 tgcttaccag gcgcatttcg cccaggggat caccataata aaatgctgag gcctggcctt
     6661 tgcgtagtgc acgcatcacc tcaatacctt tgatggtggc gtaagccgtc ttcatggatt
     6721 taaatcccag cgtggcgccg attatccgtt tcagtttgcc atgatcgcat tcaatcacgt
     6781 tgttccggta cttaatctgt cggtgttcaa cgtcagacgg gcaccggcct tcgcgtttga
     6841 gcagagcaag cgcgcgacca taggcgggcg ctttatccgt gttgatgaat cgcgggatct
     6901 gccacttctt cacgttgttg aggattttac ccagaaaccg gtatgcagct ttgctgttac
     6961 gacgggagga gagataaaaa tcgacagtgc ggccccggct gtcgacggcc cggtacagat
     7021 acgcccagcg gccattgacc ttcacgtagg tttcatccat gtgccacggg caaagatcgg
     7081 aagggttacg ccagtaccag cgcagccgtt tttccatttc aggcgcataa cgctgaaccc
     7141 agcggtaaat cgtggagtga tcgacattca ctccgcgttc agccagcatc tcctgcagct
     7201 cacggtaact gatgccgtat ttgcagtacc agcgtacggc ccacagaatg atgtcacgct
     7261 gaaaatgccg gcctttgaat gggttcatgt gcagctccat cagcaaaagg ggatgataag
     7321 tttatcacca ccgactattt gcaacagtgc cgtttccaaa aggtcgttga tcaaagctcg
     7381 ccgcgttgtt tcatcaagcc ttacggtcac cgtaaccagc aaatcaatat cactgtgtgg
     7441 cttcaggccg ccatccactg cggagccgta caaatgtacg gccagcaacg tcggttcgag
     7501 atggcgctcg atgacgccaa ctacctctga tagttgagtc gatacttcgg cgatcaccgc
     7561 ttccctcatg atgtttaacg tttgacatga ggggcggcca agggcgccag cccttggacg
     7621 tccccctcga tggaagggtt aggcaacact gcgtgttcgc tcgaatgcct ggcgtgtttg
     7681 aaccatgtac acggctggac catctggggt ggttacggta ccttgcctct caaaccccgc
     7741 tttctcgtag catcggatcg ctcgcaagtt gctcggcgac gggtccgttt ggatcttggt
     7801 gacctcggga tcattgaaca gcaactcaac cagagctcga accagcttgg ttcccaagcc
     7861 tttgcccagt tgtgatgcat tcgccagtaa ctggtctatt ccgcgtactc ctggatcggt
     7921 ttcttcttcc caccatccgt ccccgcttcc aagagcaacg tacgactggg catacccaat
     7981 cggctctcca ttcagcattg caatgtatgg agtgacggac tcttgcgcta aaacgcttgg
     8041 caagtactgt tcctgtacgt cagcaagtgt cgggcgtgct tcttctccgc cccaccactc
     8101 gacgatatga gatcgattta gccactcata gagcatcgca aggtcatgct cagtcatgag
     8161 gcgcagtgtg acggaatcgt tgctgttggt cacgatgctg tactttgtga tgcctaactt
     8221 tgtttggaaa tgttgaatac tcatactctt cctttttcaa tattattgaa gcatttatca
     8281 gggttattgt ctcatgagcg gatacatatt tgaatgtatt tagaaaaata aacaaatagg
     8341 ggttccgcgc acttttcccc gaaaagtgcc acctgacgtc taagaaacca ttattatcat
     8401 gacattaacc tataaaaata ggcgtatcac gaggcccttt cgtcttcaag aattttataa
     8461 accgtggagc gggcaatact gagctgatga gcaatttccg ttgcaccagt gcccttctga
     8521 tgaagcgtca gcacgacgtt cctgtccacg gtacgcctgc ggccaaattt gattcctttc
     8581 agctttgctt cctgtcggcc ctcattcgtg cgctctagga tcctccggcg ttcagcctgt
     8641 gccacagccg acaggatggt gaccaccatt tgccccatat caccgtcggt actgatcccg
     8701 tcgtcaataa accgaaccgc tacaccctga gcatcaaact cttttatcag ttggatcatg
     8761 tcggcggtgt cgcggccaag acggtcgagc ttcttcacca gaatgacatc accttcctcc
     8821 accttcatcc tcagcaaatc cagcccttcc cgatctgttg aactgccgga tgccttgtcg
     8881 gtaaagatgc ggttagcttt tacccctgca tctttgagcg ctctgatctg aatatcgagg
     8941 gactgctggc tggttgagac ccgcgcataa ccaaaaattc gcataaaaat gtaccttaaa
     9001 tcgaatatca gacacgatgt gtctattatg ccaaaatgac gatttaatgg acactcaaac
     9061 gaagccgttt tactatgtct gataatttat aacatttcgt acggttggaa aaatgttact
     9121 aaatgcccgt caggcaggga ggccgatatg cccgttgact ttctgaccac tgagcagact
     9181 gaaagctatg gcagattcac cggtgaaccg gatgagcttc agctggcacg atattttcac
     9241 cttgatgaag cagacaagga atttatcgga aaaagcagag gtgatcacaa ccgtctgggc
     9301 attgccctgc aaattggatg tgtccgtttt ctgggcacct tcctcaccga tatgaatcat
     9361 attccttccg gcgtccggca ttttaccgcc agacagctcg ggattcgtga tatcaccgtt
     9421 cttgcagaat acggtcagag ggaaaatacc cgccgtgagc atgcagcgct gatacgtcag
     9481 cactatcagt atcgtgaatt tgcctggccc tggacatttc gccttacccg tcttttatat
     9541 acccggagct ggataagcaa cgaacgtcct ggcctgcttt tcgatctggc gacagggtgg
     9601 cttatgcaac atcgtattat tctccccgga gccactacgc tgacccggtt gatttcagag
     9661 gtaagggaaa aggcgacgtt gcgcctgtgg aacaaactgg cactgatacc gtcagccgaa
     9721 cagcgttcac agctggagat gctgctgggg ccaactgatt gcagccgcct gtctttactg
     9781 gaatcactga aaaagggccc tgtgaccatc agtggtccgg cgtttaatga agcaattgaa
     9841 cgctggaaaa ctctgaacga ttttggcctg catgctgaaa acctgagtac actcccggct
     9901 gtgcgcctga aaaatctcgc acgttatgct ggtatgactt cggtgttcaa tattgccagg
     9961 atgtcaccgc agaaaaggat ggcggttctg gttgcctttg tccttgcatg ggaaacgctg
    10021 gcgctggatg atgcattgga cgttctgggg ttctaagcgg gaatcccaga aaattccgtc
    10081 attccgtatg atgaaaattc agtcgactcc tcgcttgacg tgacgagcgc caaaagcctg
    10141 ccgcatctgc ctggcgcgct cgagctcatc gccatgcaaa tacatcgacg tcgtggcgat
    10201 cgacgcatgg cgtaggttgt cgcgcaccgc ggtgagctga gctccccggg ccaacgcatg
    10261 gctggcatga ctgtgacgca tccaatgagg cgtggcacgg cgcagctttt cggcggcgac
    10321 cggatgatcg gcctcaatgg cctcagcggc ttgcgtaaag aatcttcgca acacgcacca
    10381 aaggtgaggg ccggtgatgc cggcattacc gtcttcccca agactgccca ccaggggcgt
    10441 tttcggattc caccgttccc ggctgactgg cagttgacgc tgtgccaagt attggtccag
    10501 cgccgtatac gcgagcggcg gcaaggccac cttacctggt ttgccacctt tgccaaccaa
    10561 atgcagccag tggtcaccgt gctcgtcgag gcggacatta cccaggacgg cgccgaccag
    10621 ttcgctagcg cgcaggcccg tggcatagcc gaagtcgagc atgaagcgca ggcgttgtgc
    10681 tgccggctcg gaccagccgt aggaccattc caggccgtct gcaatggcgc gcagcagtag
    10741 ccattctccc tcggtaaagc ctcgcgccgt atccagtgcg ggccgcaagg cgtgaccgcg
    10801 taccttgacg ccggcgaaag ggttggccag cacatagcgc tgctcgatga gccaccggaa
    10861 cagcgccgag agcaccgtca gcgcatacgc tgccgagcgt gcggacaagc cgcccgagaa
    10921 ggggcgccat tccaccgaat cgcgtggtcg aggtggcccc acccaacgct cgcgcggggt
    10981 cgggtgccgg acaaaggccc ggtacgcgat tgcatcgtcc gtggtcaggg atgatagcgc
    11041 ccgtccgcgt tcgacgatgg cccacaggat tagccgcgca gcctccttgc gataggcgcg
    11101 ctgtgtggcg acagtctcgt gcagcgccag ccaggcctgc acggcctcgt agtcgttggt
    11161 cgcattcagc gtgcaagcgt tgcgcggggc ccggaaattg ccctgcgagc cgtcgacttc
    11221 gttcggcaga cgcaactgct cccacggcac gatgccgctg ggctgaataa tcgggatcag
    11281 ggcccgggcg cgctcggtga gctgcggatg tgcggcaaag aaagcctcga cctgccgggc
    11341 gcctgtcatg ccgagtccct cgatggcttt ccaccagcca cgccggcggg gaatgcgcac
    11401 ggtcagcgcc gagagggtgt ggataccgta cgcctgcagt gccctgacgg tcctcggaga
    11461 cagccactgg tcgatgctgt cgctgatctg gggcttcggc gccggcagcg tgggcaagag
    11521 ccggatcgcg cgttcgacgg cacccgcgcg cccctgtcgc tcttcggggg cgtgctggaa
    11581 cacgtcggcc agatccggcc ggtggcggct gttggcgaaa acgatgagct ggcggcggat
    11641 atgccccagc atccctcgcg ctgattgacc ggcggccttg cgtgccgcca ggtagtgttc
    11701 aacggccgcg cgagagctga gtcccgcgta ccagccgcgc aaggcagcca gcgaatccgc
    11761 atcgggaaag ccgactgggg tagaactcga agccgtagtc tggcccgttt tcatatggac
    11821 aggttgcgat tcgaaaagcg agtaacgcga taataacgat tatttcagta gaatcgaaaa
    11881 tgccccatgt ttctacgaaa cctcaagata gcaagaacgg gccatgagca agaagaacaa
    11941 gctactcagc gtcctatccg acgccgaaca ggaggccttg tatggcctgc cggagttcga
    12001 tgatgcgcag cagctggaat atctggctgt gacagaaacc gagttggcgc ttgccaacag
    12061 ccggcccagt cttcatgcca aggtctattg cctcttgcag atcggctact tcaaggccaa
    12121 gcatgccttc ttcagtttcg actgggacga agtcgaggac gattgcgctt tcgtgctgag
    12181 ccgctatttc cacggcgagg tgttcgaacc caaggcgatc accaagcatg aacgctacac
    12241 ccagcgcgag cagatcgcca aactattcgg ctactggccg tggtcggccg ccttcctgcc
    12301 gcagctcgag cagcaggccg cacggaccgt gcggcgtgac gtaacgccgg ggttcgtcgc
    12361 cgccgagctg atcgtctggc tcaatgagca caagattatc cggcccggct atacgacctt
    12421 gcaagagttg gtcagcgaaa cgctatccgc cgagcgccgg cgcctgggca atctgctgga
    12481 gcaagcgttg gacgaatctg ccaaggccgc gctgagccag cttctggtcc gtgatgacac
    12541 cctgtcgcaa ctggcggcgc tcaagcagga cgccaagaat ttcggctggc gccagatggt
    12601 ccgcgagcgc gaaaagcgcg ccacgctgga gccgctgcac gcaatcgcca agacactgct
    12661 gcctaaactc gacgtctcgc agcagaacct gctgtactac gcgagcctgg caaacttcta
    12721 caccgtccac gacctgcgca atctgaaggc cgatcagacc caactctacc tgctgtgcta
    12781 tgcctgggta cgctaccggc agctctccga caacctggtc gatgcgatgg cgtaccacat
    12841 gaagcagttg gaggacgaaa gcagcgctgg tgccaaacaa tcctttgccg acgagcaggt
    12901 gcgccgtcag caggaaacgc cgcgggtagg ccgcctgctg tcactctacg ttgatgatag
    12961 cgtggccgat cccacgccct tcggcgaggt gcggcagcgc gcctacaaga tcatgcctcg
    13021 cgatacgctg caaaccacgg cgcagcgtat gagcgtgaag ccggcgagca agctggcctt
    13081 gcagtggcag gcggtggacg ggctggccga ccgcatgcgc cgccatcttc gtccactgta
    13141 cgttgcgctc gacctctccg gctccaatcc agacagtcca tggcttgccg cgctggcctg
    13201 ggccaaaggt gtttttgcca agcagcagcg gctgtcgcaa cggccactcg acgagtggcc
    13261 cgcggcgaca cttccgaaac gcttgcggcc gtacctgctg accttcgacg ccgacggtaa
    13321 accaaccggc ctgcacgctg accgctacga gttctggctg taccgccaga tcaggaagcg
    13381 tctccaatcg ggtgaactct acctcgacga cagcctgcaa caccggcact tctcagatga
    13441 actggttgag atggacagga agatcgatgt gctcgcaaaa atggagatcc ccttcctgca
    13501 gcaacccgtc catgcccaac tcgatgcgct gactgccgaa ctgcgcacgc agtggctggc
    13561 gttcaaccgc gagctgaaac agggcaagct gacgcacctc gaatacaaca aggacacgca
    13621 gaaactgacc tggcgcaagc ccaagagcga gaatgagaaa gcgcgcgaaa aggcattcta
    13681 cgagaagctt ccgttctgcg acgtggccga cgtgtttcgc ttcgtcaacg acgagtgcaa
    13741 gtttctgtcg gcgttcacgc ccatgcagcc gcgctacgcg aagaaggtcg ccgacgctga
    13801 cagcctgatg gcggtcatca tcgcgcaagc gatgaaccac ggcaaccacg tcatggcgcg
    13861 caccagcgac atcccgtacc acgtgctgga tagcggctac cagcagtacc tgcgccaggc
    13921 aacgctgcac gcggccaacg actgcatcag caacgccatc gccacgctac cgatcttccc
    13981 atactactcg ttcgacctcg aaacgctgta cggtgccgtc gacgggcaga aattcagcgt
    14041 cgaacggccg accgtgaagg cgcgctattc gcgcaagtac ttcgggcgcg gcaagggcgt
    14101 ggtcgcctac acgctgctgt gcaaccacat cccgctcaac ggctacctga tcggcgcgca
    14161 cgactacgag gcccaccacg tgttcgacat ctggtatcgc aacacgtcgg acatcatgcc
    14221 gaccgcgatc accggcgaca tgcacagcgt caacaaggcc aacttcgcca tcctgcattg
    14281 gtttggccgg cggttcgagc cgcgcttcac cgacctcaac gcgcaattga aagaactcta
    14341 ctgcgctgac gatccagcac agtatcaggc gtgcctgatt cggccagtcg ggaaaatcga
    14401 ctgcgatctc atccatcgcg agaagccgaa catcgaccgg atcgtcgcca cactcgggct
    14461 gaaggaaatg acgcagggca cgctgatccg caagctgtgc acctacacca cgacgaaccc
    14521 gacgcggcgc gcgatcttcg agttcgacaa gctcatccgc agcatctaca cgcttcgcta
    14581 cctgcgcgat ccgcaactgg aacgcaacgt gcaccgctcg caaaatcgcc tcgagtccta
    14641 ccatcagcta cgctcggcca ttgcccaggt cggcggtaag aaggaactga ccggtcgcac
    14701 cgacattgaa atcgagatca gcaaccagtg cgcacggctg atcgccaaca cgatcatttt
    14761 ctacaactcg gcaatcttgt cgcggctggt gaccaagtac gaggcggccg gcaacagcaa
    14821 ggcgctggca ctcatcacaa aaatttcgcc tgcggcatgg cggcacatcc tgctcaacgg
    14881 gcactacacc tttcaaagca gcggcaagac gatcgatctc gatgcgatcg tcgcaggcct
    14941 ggaactggag tgacggaatt ttcagcggtt ccgtgttagc agcagtgtaa aactgaccca
    15001 ccccagcgaa gtaaaactga tccacctggg ctagtttggc ggccttttcg aggccgtcga
    15061 tgttgaccca ggagcaaacc gtggaaatca gagttcttgc ccgacagggc cactccatcc
    15121 ggcacatcgc ccgcacgttg ggggtctcgc gcaataccgt gcgccgctac ctccgcgatc
    15181 cgtcggtagc gcgataccag ccccgtgaac cacgccccac caaactgggg ccatttgaat
    15241 cttatctgcg gcaacgggtc gagcaggccc accccatctg gctgcctgcc accgtcctga
    15301 atcgggaaat ccgcgctcaa gggtatggcg gcggtctctc gttattgcgc gccttcctcg
    15361 ccacgctcaa gcccgcccgc cgcgaagcag gtccggccgt ccgtttcgag accgagcccg
    15421 gacggcagtt gcaggctgat ttcgtggtct tgcgccgggc cagatccccc atgtcggcct
    15481 tcgtcgccac gctgggatac agccgcatga cgtttgtcac cttcgtaccg gacgaatcct
    15541 tcgagtccgt gcgggactcc ctgttgctgg cttttgacta tctgggcggt gtgccccgcg
    15601 aggtgttgtt cgacaacatg aagaccgtgg tgctggaacg cgatgcctac ggtgacggca
    15661 agcaccgttt tcaccccggc ttgcttcaac tggccgatga cctggggttc cggatccggc
    15721 tgtgtcgccc gtatcgggcc cagaccaaag gcaaggtcga gcgcttcaat cgctacttcc
    15781 gcgagagctt ctacaacccg ttgctgaccc ggatgaaggg cacggggctg ctgctcgatt
    15841 gtgctgctgc caaccgacgc gtccgtgact ggttggcaga cgaggcgaat gtgcgggtcc
    15901 acgccaccct gaacgagcgc cccatcgacc gttggcggca ggagcgggaa cacctgcaac
    15961 ccttgccatc ccgtgtgcgg cgcgacgagg cccccctgct ggataacagt ctccgcccgg
    16021 taccactgga atctctccag cacccactgt ctgtctatga cgcaattggg gaggcctgcc
    16081 gatgaacctc cagcatgagc ggatcgacgc cctgtgccag caactcaaac tcgaacgggt
    16141 ggcaacgcat taccccgtcc tggcgcagca ggcggtgcgc gaggacttca gcttcaccga
    16201 cttcctggaa cacctgttgc ggcatgaagc ggggtgtcgc cagcagcgca gccgcgaact
    16261 gctgacgcgg atggcttgct tcccgggcat caagaccctg gaggactatg acttcagctt
    16321 caaccccggc gtgcccaagg cactggtgca ggagctgggc agtctggcgt ttgtcgaacg
    16381 ggccgagaac gtggtgctga tcggaccctc tggcatcggc aagacccacc tcgccatcgc
    16441 cttgggttac aaggccgcgc aagccggggt caagacacgc ttcatcacgg cagccgacct
    16501 gatgctgcaa ctgagcacgg cgcagcgaca agggcggctg aaggaatact tcaaccgcgc
    16561 catcctcggt ccacggctgc tggtgatcga tgagatcggc tacctgcctt tcggacgcga
    16621 ggaagcgaac ctgttctttc aggtggtggc gaagcgctat gagaaagggg cgatgatcct
    16681 gacctcgaac ctgccgttca gccagtgggc cgacgcgttt gccggcgata ccaccctgac
    16741 agccgcgatg ctggatcggc tgctgcacca tgcccatatc ctgaccctga gcggcgaaag
    16801 ctaccgcttg aaggacaaga ggaaggcggg agtggtcagg aaaaattcca aacccgaatg
    16861 atccaggtgg gtcagtatta ctttggtgat tcaggggtaa agtgggtcag ttttcagttg
    16921 gtgttgacac cggcgtaccc tcggtgctat cttcgcgccc caatagtcgg ggcttggcca
    16981 ggacttcctg aggccgtccg taacgtggat gccgaggtca ggcgaggtgg ccgacccatg
    17041 aacgccgacc tgattcgttt ttcaatagcg ctggacgttg tggtgccagg gacttaccaa
    17101 cccgatgtgt gcccatccgg ggcagttaca gccgttacag cctctggaga gggagcggct
    17161 tgccgctcgg tgataatccc agctgtagcg gcctgattac atccggccgc tacacctagc
    17221 tccaccttca aacaaggaat atcgttgatg tcactgtatc gccgtctagt tctgctgtct
    17281 tgtctctcat ggccgctggc tggcttttct gccaccgcgc tgaccaacct cgtcgcggaa
    17341 ccattcgcta aactcgaaca ggactttggc ggctccatcg gtgtgtacgc gatggatacc
    17401 ggctcaggcg caactgtaag ttaccgcgct gaggagcgct tcccactgtg cagctcattc
    17461 aagggctttc ttgctgccgc tgtgctggct cgcagccagc agcaggccgg cttgctggac
    17521 acacccatcc gttacggcaa aaatgcgctg gttccgtggt cacccatctc ggaaaaatat
    17581 ctgacaacag gcatgacggt ggcggagctg tccgcggccg ccgtgcaata cagtgataac
    17641 gccgccgcca atttgttgct gaaggagttg ggcggcccgg ccgggctgac ggccttcatg
    17701 cgctctatcg gcgataccac gttccgtctg gaccgctggg agctggagct gaactccgcc
    17761 atcccaggcg atgcgcgcga tacctcatcg ccgcgcgccg tgacggaaag cttacaaaaa
    17821 ctgacactgg gctctgcact ggctgcgccg cagcggcagc agtttgttga ttggctaaag
    17881 ggaaacacga ccggcaacca ccgcatccgc gcggcggtgc cggcagactg ggcagtcgga
    17941 gacaaaaccg gaacctgcgg agtgtatggc acggcaaatg actatgccgt cgtctggccc
    18001 actgggcgcg cacctattgt gttggccgtc tacacccggg cgcctaacaa ggatgacaag
    18061 tacagcgagg ccgtcatcgc cgctgcggct agactcgcgc tcgagggatt gggcgtcaac
    18121 gggcagtaag gctctgaaaa tcatctattg gcccaccacc gccgcccttg cgggcggcat
    18181 ggattaccaa ccactgtcac atttaggcta ggagtctgcg cggcagagcc gtgtgaccgg
    18241 ttttctgtag agcactgacg atggcggcgg cgctctctgc aattggcaag gcgtcggcgc
    18301 caaggatacc aatcttgcgg cgcgcggcgt gttatgacga ctggggtgca tttgagccgc
    18361 cccatttaac cttcgccctc acagatacgc cattcgcctc agatttagcg ccatgcagac
    18421 gagcttccac tcggcttgca ccttgtccag gcccctcatg ctgaactgac gcaatcccat
    18481 caccgccttg atccaaccat tcggagcctc cacgatcgac ttgcgccggc ggtaagctgc
    18541 atcgccttgc tccgttttca atttcgccgc aatcgccgcc gtatgcggat gggtcttggc
    18601 attgaccttg gcatcttcac gtccctcgcg gccgagggca acgatgacat cgccgtggtg
    18661 atcggcgacc tttgccagaa cagcctcact acggaatccc gcatccgcca gcgtctgggc
    18721 cggcatttct ccggtgttgg cctgaactgc tgccagcatg cccagcagcg cctgactgtc
    18781 cgcggcgcag ttggtcaact ccgccgccac gatgatctgg tgctcggcat cgaccgctgt
    18841 gtacccgttg tagctctgct cggagccacc accggcgtgt ttcatgatcc ggctgtccgg
    18901 atcggtgaag ctttcctgat cacggtcatc cggcacacca aactcgcgtt tgtacgagcc
    18961 accgcccttg tccgagccat ccggatggcg aggccggcgg ccatcgtctt cgctgcgccc
    19021 ccgggcctgg tccgcttcac gctggcgcgc ttccaggcgc gcctttgccg cctggatcgc
    19081 ctccaggcgc ttctcgcggc gagaaatctc ggcaggaatg tccagctccg gctcgttacg
    19141 ctcctggtcg tcggtagcct tggcgcgatc aagcagcgcc ttgatctcgc aatgcaattc
    19201 gtcctcggcc ggcttcatgc gcttatagct catcgccttg tggcggctgg cgttggcttt
    19261 taccttggtg ccgtcgaccg cgatcgtgcc aagcttcacc agcccacatt cgcgcgccag
    19321 ttgcaccacc tgaacgaaca aattctcaag ctcggtcagg tgtagggcac ggaagtcact
    19381 cagcgtgcgg tgggccggga agtttccagc ggccagcaca cgcaacgcga catcctcgta
    19441 cagcttcctg gctagtttgc gcgaagagaa gacgccgctc gcgtaaccat agatcagcac
    19501 tttgaccatc atcgccggat gaaacggctg attgcccgga ccaccgccgg cataccgggc
    19561 gtggaatgcg ctcaagtcca gcgtatcgac agtctcgctg atgaagtagg caagatgccc
    19621 ttcaggtagc cactctccca gagaaggggg cagcagatag gattggtcgg gtcggtaagg
    19681 aaggtaactg gcagccatcc ccgtatcgtc ctcgatcttc cgccgatttg gcttctgccg
    19741 cgcaggctcc taggccaccg tagctaaaca tacgagaaaa accgcttctt gagcgctctc
    19801 tgagaccacc ttgccgacaa cgcagaaacg gttgcggaaa aatcggcgtt tccggcgtac
    19861 gccacccgac ctggacgaac tattgcggac ctggaactgg agtagcggaa ttccccgggg
    19921 tttcagcgtc gcgccacagc gcctcagata gatgcggtag cctttggcgg gtcgtcatgc
    19981 cgcggaccac ccccccaaaa aattccacaa tgcggaatgg cggaattttc tggggttccc
    20041 gcttaccccc ccattcagca gtttcacagt caggaatttt taaactcact ccaaggcaca
    20101 acacaatttg cgggtaccga ttaccgcagc aaagacctca caccgaaaaa atcaaggcta
    20161 ctggctgaca ccatttcagc tgtttatctc gatggctatg aaggcagaca gtaagtggat
    20221 ttaccataac gcgtcattac gcgcaccgct cagacgggct cagggcgttt ccggcggcta
    20281 cgggataaaa caggcaacaa cccccccgga aaactgccgg aaacgcgccc gataaatttt
    20341 atcctaatgc atgcctatgc acgcaactgc atggcatatg ttttgacgta aaatggatgc
    20401 cgtaagccct tttttaccga ctttctgctt catcagcctg actgacacga ccatattctt
    20461 tcagaccgcc ccctgctaaa cttccttcat attgccgcat taacccggga ggctccgcaa
    20521 tgagcaacac tacacactac gaaaacgcca actttcttcg ggaactggct gaaagcctgc
    20581 cccgcatact gccggaaggt ggcccggaca aagctgcgct gttgcagcga ctggctaacg
    20641 aagaactggc ccaggcagag tatgaagatc aggttcgcgc caaagtgacc gccgcccgtg
    20701 ctgacacgcg tccgggtatg accacggaac aactccgcca gcgcctgcat ggccgttatc
    20761 aggaactgcg cgatgccgta tgacgtggaa tggaagcagg gagccatcga ggatgtaacg
    20821 acgctgtttg actatatcgc ggaaaattca tccctgtggg atgcgcagaa cgttaccgac
    20881 cgggttctcg ctgcggcgga caaactggcc gacttcccgc gactctatga agtggactca
    20941 cgctatggcg aggacgttcg ccggatcagt ctgatgggac agcatgtcct ctatgatgtt
    21001 gatgaccaga ccagaaaagt ccgggttctg gccgtggtcg gccagcgcca gaatccccat
    21061 attgttctct aataaccggt gacggggacg caattcattg cgtggccgtc gccggttgga
    21121 caagcacagc gcgtcagcgt tttccccacg gccaccaccg gcgcggtgtt ccggccgggg
    21181 tctctgctgt ctccggtttg tgttccagca gtctcatgga ctgcatttcc tgccgtagcc
    21241 cggccacctc ctccctgagt gcttttatct ccgcgatcaa cgcgtcggag gccatttttt
    21301 cagtctcacc cgacagtctc aactcgtccc gctcgtgagt ctcatcctgt cttaactcac
    21361 cgtacacccg gataagctcg ctggtatcca ccacccggcc gccatcagct tccgtacggt
    21421 atgatacgcg gcctttcgcc atatcccgat acagggaact tcgggcttta cccgtcagtt
    21481 ccgtcgcctg tctcaccgtc acccacgcca ttgtctcacc ccgctatttt tgagacagta
    21541 tacctgacag gcgcacacca tgcccggaag gaaagaatc
//
