LOCUS       CP067467               30044 bp    DNA     circular BCT 01-MAR-2022
DEFINITION  Klebsiella pneumoniae strain ARLG-3480 plasmid pC862_2, complete
            sequence.
ACCESSION   CP067467
VERSION     CP067467.1
DBLINK      BioProject: PRJNA658369
            BioSample: SAMN15868710
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 30044)
  AUTHORS   Shropshire,W.C.
  TITLE     Highly Conserved and Distinct Accessory Genomes Drive Independent
            and Parallel Endemic Spread of Carbapenem-Resistant Klebsiella
            pneumoniae Clonal Groups 258 and 307
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30044)
  AUTHORS   Shropshire,W.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) HMH-CDI, Hackensack-Meridian Health Center
            for Discovery and Innovation, 340 Kingsland Street, Building 102,
            Nutley, NJ 07110, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Flye v. 2.7
            Assembly Name                     :: C862
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 118x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 01/11/2021 15:16:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 5.0
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,471
            CDSs (total)                      :: 5,347
            Genes (coding)                    :: 5,242
            CDSs (with protein)               :: 5,242
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 42 of 105
            Pseudo Genes (incomplete)         :: 55 of 105
            Pseudo Genes (internal stop)      :: 19 of 105
            Pseudo Genes (multiple problems)  :: 11 of 105
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..30044
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ARLG-3480"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pC862_2"
                     /geo_loc_name="USA: South"
                     /collection_date="2016"
                     /collected_by="MDRO network"
     gene            join(29901..30044,1..723)
                     /locus_tag="JJ187_27140"
     CDS             join(29901..30044,1..723)
                     /locus_tag="JJ187_27140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="UMC75818.1"
                     /translation="MGKRSSSVLNYPLVDKVQIFPVDKYRDSLQFLFSLSLWVGKNLPI
                     GIEMDTQALLPATKTFKKRASIKQSNELTEAAYYLPLQAKRVLWLCLMQAYFNDSQEDD
                     SDVLPLFKISVSDYVKYFNVATSVASRDVKAGVNALGESTVTFYPKEGEFEEVKRPWLA
                     EAGMKRGRGSWQIEFNYKVMPFLVGLTSQFTTYSLYDCGQLNSVRVIRLYESLCQFRST
                     GVWITTHDWLCERFMLPASQKNNIAEMKRTFLEPALKKINEKTPLKVTYTTEEDGRLLF
                     NFLDKKQ"
                     /name="replication initiation protein"
     gene            complement(1080..1349)
                     /locus_tag="JJ187_27145"
     CDS             complement(1080..1349)
                     /locus_tag="JJ187_27145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75819.1"
                     /translation="MDAPDYGKQVNFADGPDYGKQVNFTGGRECGEQVNFADGPDYGKQ
                     VNFAGGRDCGKQVNFADGPDCGKQVNFAGGRECGEQVNFADGPD"
                     /name="hypothetical protein"
     gene            1764..2969
                     /locus_tag="JJ187_27150"
     CDS             1764..2969
                     /locus_tag="JJ187_27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="UMC75820.1"
                     /translation="MDNIEQLRKVATRAGKLLTSLSESIRQQKEELKLTEFYQEYSKAA
                     LYKLPKLSKGSVEYAVSEMEAGGYIFKKKPSGNTMKYAMTIQNVIDLYNHRKVPKYRDR
                     FDKAFTIFVCNLKGGGSKTVSTASLSHAFRAHPQLLFEDLRILAIDFDPQASLTMFLSH
                     ENSVGLVENTAAQAMLQNVSREELLSDFIVPSIIPGVDVIPASIDDAFLAEGWKGLCEE
                     HLPGKNIHAVLKENIIDKLQHDYDFIFLDSGPHLDAFLKNCIGAADLMLTPLPPATVDF
                     HSSLKFVASLPALIDSIEMDGHTCNLIGNVGFMSKILNKSDHKICHSQAKEVFGADMLD
                     MVLPRLDGFERCGETFDTVISANPATYDGSTEALKSAKSAAEDFAKAVFDRIEFIRTNG
                     GM"
                     /name="AAA family ATPase"
     gene            2969..3943
                     /locus_tag="JJ187_27155"
     CDS             2969..3943
                     /locus_tag="JJ187_27155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="UMC75821.1"
                     /translation="MSNEKRKTIGRQLNTQASILEMADTGRSQVFTLKTGRKVTFRFVR
                     VPASEVESKTFVNQENNGRDQLALTRESLKSIIQTIKFQQFFPCIGIKQSERIEILDGS
                     RRRASAIFVRTGLDVMVTEEHLSADEARQLAKDIQTAKEHNLREIGLRLIALKESGFNQ
                     KEIAELEGLSQAKVTRALQAAAVPQDLISLFPVQSELSFSDYKLLLEVNEKLGEKGLTP
                     EELIQSVSAQLDAILSDGERPEDEQKASILKLISQASQALIDPSPKEKSVVSPLWSFEE
                     KDKFARKRVKGRTLTYEFSRMSKVIQDELDKAINEVLDRNLSQ"
                     /name="ParB/RepB/Spo0J family partition protein"
     gene            complement(4025..5296)
                     /locus_tag="JJ187_27160"
     CDS             complement(4025..5296)
                     /locus_tag="JJ187_27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UMC75822.1"
                     /translation="MFALADVNSFYASCERVFRPDLKGKPIVVLSNNDGNVIARSAEAK
                     PWIKMGTPWFQIKNERYPEKIYAFSSNYELYASISARVMNCLEELAPRVEQYSIDEMFL
                     DLTGVEHCMGLEDFARQLRQQVYDCTRLTIGVGAGPTKTLAKSAQWASKEWKQFHGVLA
                     LTRGNPQRTRKLLSLQPVEEIWGVGNRIARKLNVLGIKTALDLALTNPAFIRKNFSVVL
                     ERTVRELNGESCLSLEEAPPTKQQIVCSRSFGVKITEYESLRQAICQHAERASEKLRKE
                     HQYCRHISVFIKTSPFAIKEPYYGNVATEKLLTPTQDTRDIIAAATTALERIWRDGHRY
                     AKAGVMLNDFTGSGVSQLQLFDERPPRPHSAELMRVLDGINNSGLGKVWFAGRGMAPEW
                     QMKREMLSPAYTTRWSDIPAAKLA"
                     /name="Y-family DNA polymerase"
     gene            complement(5296..5727)
                     /gene="umuD"
                     /locus_tag="JJ187_27165"
     CDS             complement(5296..5727)
                     /gene="umuD"
                     /locus_tag="JJ187_27165"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="UMC75823.1"
                     /translation="MKLQLFSTGKELPPQAHPLFADLASCGFPSPAADYVESDLDLHDY
                     CIRHPSATYYLRASGDSMADGSLYNGDLLVVDSAEKPRHGDIVVASMQGEFTVKRLLLT
                     PRLTLQPMNASWSPIYPDPDELDIFGVVTHIIHRPREMY"
                     /name="umuD"
     gene            6133..6870
                     /locus_tag="JJ187_27170"
                     /pseudo=""
     CDS             6133..6870
                     /locus_tag="JJ187_27170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020323916.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="group II intron reverse transcriptase/maturase"
     gene            6928..7632
                     /locus_tag="JJ187_27175"
     CDS             6928..7632
                     /locus_tag="JJ187_27175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UMC75824.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            7687..8163
                     /locus_tag="JJ187_27180"
                     /pseudo=""
     CDS             7687..8163
                     /locus_tag="JJ187_27180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011899415.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /name="GIY-YIG nuclease family protein"
     gene            complement(8539..9807)
                     /locus_tag="JJ187_27185"
     CDS             complement(8539..9807)
                     /locus_tag="JJ187_27185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011191342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISApu1 family transposase"
                     /protein_id="UMC75825.1"
                     /translation="MTIINANYYLEQLLAPAALERIARLCKFCLRQRAITPAMLVPALL
                     RAMGGDQVNDIAGLHRHFNALQLVNTHQVSYKPFHNQLRKESFALFMKALVERAIALRI
                     DHQLKAASLGAFKQVLLHDGTSFAVHRRLAADFPGRFKTISPAAIECHMTMSLSEQSPL
                     CMSVSADTAGERQFLPEAHTLTNCLLLADAGYIDRAWFEQVNDAGGFYLVRGTKSLNPK
                     IIQAWRGDGREVPKLAGLSLREAGRRRCRAEVLDMVVKSGQVEYRLIRRWFAEEKRFCL
                     WMTNLPRAAWSAEQVMSLYRCRWQVELLFKEWKSHNRLKGFVTGEKAIAEGLVWTSLLS
                     LVMKRRVAQSVMSGALSMLKASKNSATWWLPLLEAVAHRALTEIRERLEWAADYLAKNA
                     CRTKQRKSIQNRTLEGVLNGLAA"
                     /name="IS4-like element ISApu1 family transposase"
     gene            complement(10125..10496)
                     /locus_tag="JJ187_27190"
     CDS             complement(10125..10496)
                     /locus_tag="JJ187_27190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019838990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75826.1"
                     /translation="MTQERIQTRYPLGGPFATQAELEQAITQAITTHRQDFFPLLERLV
                     DVGDTRVNLSQENPLRVLSIELADGREGVAHINYESNFAESCLIINEYDQHQTSLAFRL
                     DGDALIFDVELPIAWNFNN"
                     /name="hypothetical protein"
     gene            10653..11102
                     /locus_tag="JJ187_27195"
                     /pseudo=""
     CDS             10653..11102
                     /locus_tag="JJ187_27195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011222061.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /name="IS4 family transposase"
     gene            complement(11136..14033)
                     /locus_tag="JJ187_27200"
     CDS             complement(11136..14033)
                     /locus_tag="JJ187_27200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="UMC75827.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAEWRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEVMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            14106..14810
                     /locus_tag="JJ187_27205"
     CDS             14106..14810
                     /locus_tag="JJ187_27205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="UMC75828.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            14860..14970
                     /locus_tag="JJ187_27210"
                     /pseudo=""
     CDS             14860..14970
                     /locus_tag="JJ187_27210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'') family aminoglycoside
                     nucleotidyltransferase"
                     /name="ANT(3'') family aminoglycoside
                     nucleotidyltransferase"
     gene            15030..15854
                     /gene="blaOXA"
                     /locus_tag="JJ187_27215"
                     /pseudo=""
     CDS             15030..15854
                     /gene="blaOXA"
                     /locus_tag="JJ187_27215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722315.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class D beta-lactamase"
                     /name="blaOXA"
     gene            16054..16371
                     /locus_tag="JJ187_27220"
                     /pseudo=""
     CDS             16054..16371
                     /locus_tag="JJ187_27220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            16554..17414
                     /locus_tag="JJ187_27225"
     CDS             16554..17414
                     /locus_tag="JJ187_27225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A broad-spectrum beta-lactamase TEM-1"
                     /protein_id="UMC75806.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="class A broad-spectrum beta-lactamase TEM-1"
     gene            complement(17564..17935)
                     /locus_tag="JJ187_27230"
                     /pseudo=""
     CDS             complement(17564..17935)
                     /locus_tag="JJ187_27230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(18000..19250)
                     /locus_tag="JJ187_27235"
                     /pseudo=""
     CDS             complement(18000..19250)
                     /locus_tag="JJ187_27235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124600.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(19325..19993)
                     /locus_tag="JJ187_27240"
     CDS             complement(19325..19993)
                     /locus_tag="JJ187_27240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="UMC75829.1"
                     /translation="MAQAAARGQLDLHYQPLVDLRDHRIAGAEALMRWRHPRLGLLPPG
                     QFLPLAESFGLMPEIGAWVLGEACRQMHKWQGPAWQPFRLAINVSASQVGPTFDDEVKR
                     VLADMALPAELLEIELTESVAFGNPALFASFDALRAIGVRFAADDFGTGYSCLQHLKCC
                     PITTLKIDQSFVARLPDDARDQTIVRAVIQLAHGLGMDVIFRRRLHQLIGRNGCCAASS
                     "
                     /name="EAL domain-containing protein"
     gene            complement(20029..20265)
                     /gene="merE"
                     /locus_tag="JJ187_27245"
     CDS             complement(20029..20265)
                     /gene="merE"
                     /locus_tag="JJ187_27245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum mercury transporter MerE"
                     /protein_id="UMC75807.1"
                     /translation="MNAPDKLPPETRQPVSGYLWGALAVLTCPCHLPILAAVLAGTTAG
                     AFLGEHWGVAALALTGLFVLAVTRLLRAFRGGS"
                     /name="merE"
     gene            complement(20262..20624)
                     /gene="merD"
                     /locus_tag="JJ187_27250"
     CDS             complement(20262..20624)
                     /gene="merD"
                     /locus_tag="JJ187_27250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury resistance co-regulator MerD"
                     /protein_id="UMC75808.1"
                     /translation="MSAYTVSQLAHNAGVSVHIVRDYLVRGLLRPVACTTGGYGVFDDA
                     ALQRLCFVRAAFEAGIGLDALARLCRALDAADGAQAAAQLAVLRQLVERRRAALAHLDA
                     QLASMPAERAHEEALP"
                     /name="merD"
     gene            complement(20642..22336)
                     /locus_tag="JJ187_27255"
     CDS             complement(20642..22336)
                     /locus_tag="JJ187_27255"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="UMC75809.1"
                     /translation="MSTLKITGMTCDSCAVHVKDALEKVPGVQSADVSYAKGSAKLAIE
                     VGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLDKMRDLLGRNDKTGSSGALHIAVIG
                     SGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDG
                     GIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQL
                     NDGGERVVAFDRCLIATGASPAVPPIPGLKDTPYWTSTEALVSETIPKRLAVIGSSVVA
                     LELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFRMEGIEVREHTQASQVAYING
                     EGDGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVE
                     HIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVATVGYSEA
                     EAHHDGIKTDSRTLTLDNVPRALANFDTRGFIKLVVEEGSGRLIGVQAVAPEAGELIQT
                     AALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG"
                     /name="mercury(II) reductase"
     gene            complement(22388..22810)
                     /gene="merC"
                     /locus_tag="JJ187_27260"
     ARG             complement(22392..22810)
                     /name="merC"
                     /gene="merC"
                     /gene_name="organomercurial transporter MerC"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(22846..22956)
                     /locus_tag="JJ187_27265"
                     /pseudo=""
     CDS             complement(22846..22956)
                     /locus_tag="JJ187_27265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229640.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric transport protein periplasmic component"
                     /name="mercuric transport protein periplasmic component"
     gene            complement(22972..23669)
                     /locus_tag="JJ187_27270"
                     /pseudo=""
     CDS             complement(22972..23669)
                     /locus_tag="JJ187_27270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(23703..24413)
                     /locus_tag="JJ187_27275"
     CDS             complement(23703..24413)
                     /locus_tag="JJ187_27275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020321496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="UMC75810.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFTHDRNILVGDNESGKSTILLALD
                     LVLSDSRHRVEALGVESLLSQSAVRQFQEGERRADQLPVLTADVFLSNGGDPDLNGRQN
                     LAGINADGLRMRIAPMTEEYGQDIHNVLQQDPDNFPYEYYSVRFSTFSGGHFASFRRYL
                     RHLLLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCTRHLSAINDTL
                     ETYQFGVRVMLPTC"
                     /name="AAA family ATPase"
     gene            complement(24487..24903)
                     /locus_tag="JJ187_27280"
     CDS             complement(24487..24903)
                     /locus_tag="JJ187_27280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="UMC75811.1"
                     /translation="MNKTYMLDTCICSFIMREQPEAVLKRLEQAVLRGQRIVVSAITYS
                     EMRFGATGPKASPRHVELVDAFCARLDAILPWDRAAVDATTEIKVALRMAGTPIGPNDT
                     AIAGHAIAAGAVLVTNNTREFERVPGLVLEDWVR"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(24900..25130)
                     /locus_tag="JJ187_27285"
     CDS             complement(24900..25130)
                     /locus_tag="JJ187_27285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="UMC75831.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRP
                     TWGSFAQFEKADPDFMAEREDVVSDEGRFNL"
                     /name="AbrB/MazE/SpoVT family DNA-binding domain-containing
                     protein"
     gene            25087..25314
                     /locus_tag="JJ187_27290"
                     /pseudo=""
     CDS             25087..25314
                     /locus_tag="JJ187_27290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229628.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(25641..26093)
                     /locus_tag="JJ187_27295"
     CDS             complement(25641..26093)
                     /locus_tag="JJ187_27295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75812.1"
                     /translation="MTDRVILQREFSELMNGLHGSILKYAIDRAEHHQCEVYLCVNNKS
                     HCDQILERIFEKKVVNKLKSNQVISVNGRKLSLYSPLTLNKSYLPEAVYLLMFPSPELL
                     KSVEYQASLNPAHEIIVFTESDGHTEATDNWMSEHEVRMLGIEKTV"
                     /name="hypothetical protein"
     gene            26901..27251
                     /locus_tag="JJ187_27300"
     CDS             26901..27251
                     /locus_tag="JJ187_27300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75813.1"
                     /translation="MFTAFNERNDFSYAFEKIRNAISAPGENNLYAATELGLGILLRKY
                     EQFRQELDAAGELGNWEYDLDTYNHCIAVLQRYFTGNPSGLTERDARIYSHYLQTEHKR
                     FVKLAEELAAGR"
                     /name="hypothetical protein"
     gene            27302..28045
                     /locus_tag="JJ187_27305"
     CDS             27302..28045
                     /locus_tag="JJ187_27305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75814.1"
                     /translation="MTDIQAATESIVAATSHPVSVQLINQGAGIWGNVATGLITGLLTG
                     GITLTGIWLTHYFTLKRERQASEDKMKKELHYIATELVFMLERYAEGCFRVVTDDGQDD
                     DAPQPERKAVTNYPELNLIDVSGDWRTLEPRLMYRIRELPVLQDEAHRAIAYAAEYSDP
                     PWHKDYFRERQYQFTRLGINAVILAVRLRKATGMPETRLTGHDEWSAVSVFRKVWRRER
                     ALRAAEATRNREWNQLVIPDGMSNQ"
                     /name="hypothetical protein"
     gene            28042..28818
                     /locus_tag="JJ187_27310"
     CDS             28042..28818
                     /locus_tag="JJ187_27310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="UMC75815.1"
                     /translation="MSGLLSYSHPQQPAQMPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLVPPYPFVQLATLKQRTEK
                     AARTAGRAPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRTEKARIWDIT
                     DRTVRTWIGEAVEAAAVDGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFQMPEADAVAMLKGNI"
                     /name="phage integrase family protein"
     gene            complement(28876..29133)
                     /locus_tag="JJ187_27315"
     CDS             complement(28876..29133)
                     /locus_tag="JJ187_27315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75816.1"
                     /translation="MKLETIQIDNTVRSGLNSFTDGVIIRDTKVLITLNLPDGQKTTIE
                     GEWRHMSDANRLSERITMLQHAIYEQYEEYRADIPVSWSR"
                     /name="hypothetical protein"
     gene            complement(29262..29366)
                     /locus_tag="JJ187_27320"
     CDS             complement(29262..29366)
                     /locus_tag="JJ187_27320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UMC75817.1"
                     /translation="MRSFTIMSLLETFLTASQGATILFLAMLIYWQKR"
                     /name="hypothetical protein"
     ARG             16555..17411
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15496..15854
                     /name="OXA-9"
                     /gene="OXA-9"
                     /gene_name="OXA beta-lactamase; OXA-9-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="100.0"
                     /coverage="43.43"
     ARG             15031..15365
                     /name="OXA-9"
                     /gene="OXA-9"
                     /gene_name="OXA beta-lactamase; OXA-9-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="100.0"
                     /coverage="40.51"
     Typing          2..752
                     /name="IncR"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.335"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggatactc aagcactctt gccagctact aaaacgttta aaaaacgcgc cagtataaag
       61 caatctaacg aattgaccga agctgcatat tacctgcctc ttcaggcaaa acgtgtgctg
      121 tggttatgcc tcatgcaggc ctattttaat gacagccagg aagatgactc tgacgtattg
      181 ccgctcttca aaatcagcgt ttccgattac gtcaaatact tcaatgtcgc tacgtctgtc
      241 gccagtcgtg atgtgaaggc tggggtaaat gctctgggcg aatcaacggt taccttttat
      301 ccaaaagaag gtgagtttga agaagttaaa cgtccgtggc tggctgaagc aggaatgaag
      361 cgaggccggg gttcctggca gattgaattt aactacaagg tcatgccatt cctggtcggc
      421 ttaacctccc agttcactac ctattctctc tatgactgtg gccagcttaa tagtgttcgt
      481 gtcatccggc tttatgaaag cctgtgtcag ttccggagca ctggtgtctg gatcaccaca
      541 catgactggt tatgtgaaag gtttatgctc cctgcctcgc agaaaaacaa tattgctgaa
      601 atgaagcgta ccttcctgga acctgctctg aagaaaatta atgagaagac gccattaaag
      661 gtaacatata ccactgaaga agatggtcgc ttgctgttta attttcttga taaaaaacaa
      721 tagtctgtaa tttttatttc ctcccccctt agtttgttgc tgacatatgg ggggatactg
      781 aacttgctgt gtttcccata gtgcttgcct aacttgacct gtttcccgca atcgcggctg
      841 tctgcgtagt tgacctgttt cccacagtcc gggccgtctg cggagttgac ctgtttccca
      901 cagtcccggt cgtctgcaaa gttgacctgt ttcccacagt cccggtcgtc tgcaaagttg
      961 acctgtttcc cacagtccgg gccgtacgcg gagttgacct gtttcccaca ctcccgaccg
     1021 tccgagaagt tgacctgttt cccatagtcc gggccgtccg agaagctgac ctgtttccct
     1081 tagtccgggc cgtccgcgaa gttgacctgt tccccacact cccggccgcc cgcgaagttg
     1141 acctgtttcc cacagtccgg gccgtctgca aagttgacct gtttcccaca gtcccggccg
     1201 cccgcgaagt tgacctgttt cccataatcc gggccgtccg cgaagttgac ctgttcccca
     1261 cactcccggc cgcccgtgaa gttgacctgt ttcccatagt ccgggccgtc cgcgaagttg
     1321 acctgtttcc catagtccgg agcgtccatt aaagttgacc tgtttcccac agaggatgga
     1381 aaactcttct tgtgctgagc gtaagagcta tctgccggaa cggttcctct tcgcttcctc
     1441 gccagttcgc tcgctacgct cggttacatg gctgcggcga gcgctgatac ataaggctca
     1501 gcattgcact ggtcgtaact aaaatcagaa tccttctgaa tgactctcct gtcttgcaag
     1561 ttgaatacct ttctcaaagc ccttttgtat gagttgctgt tgatggtcaa aagtgcgtct
     1621 gcgtgttgct gcagtgtgat ttagtagcac gcccgtcgag cttcatcccc cttctgttga
     1681 gagcgaaatc aaaacaatat gatttttttc ttgcaacatg acactttttg ttcaaaatga
     1741 caaaaaacgt catgaggtga taaatggaca atattgagca gttacggaaa gtcgctacac
     1801 gtgcaggtaa gcttctgaca tctttgagcg aaagtatccg acagcaaaaa gaggaattga
     1861 agcttaccga gttctatcag gaatacagca aagccgctct gtataagctg cctaagctca
     1921 gtaaaggcag tgttgagtat gctgtgtccg aaatggaagc cggtggctac atttttaaaa
     1981 agaaaccttc tggtaatacg atgaaatacg cgatgacgat tcagaatgtc atcgatctgt
     2041 ataaccatcg taaagtaccg aagtacaggg atcgcttcga taaagccttt acgatttttg
     2101 tatgtaatct taaaggtggt ggttccaaga cagtttctac cgcttcatta tcacatgctt
     2161 ttcgagctca tcctcagctt ctgttcgaag acctgcgtat tctggccatc gatttcgatc
     2221 cgcaggcatc tctgacaatg ttcctgagcc atgagaattc agtgggcttg gttgaaaata
     2281 cggctgctca ggccatgctc cagaacgtgt ctcgtgaaga attactttcc gattttatag
     2341 taccgtctat tatccctggt gttgatgtaa tccccgcttc cattgacgat gcattccttg
     2401 ctgaaggctg gaagggattg tgtgaagaac atctgccagg gaaaaatatt catgcggtgc
     2461 ttaaagagaa cattatcgac aagctccagc atgactacga ctttattttc cttgatagtg
     2521 gtcctcacct tgatgcgttc ctgaaaaact gcattggggc ggcagacctg atgttgaccc
     2581 ctcttccacc ggcgacggtt gattttcatt cttccctgaa gtttgtggcc agcctccctg
     2641 ccctcataga ttccatcgaa atggatgggc acacctgcaa tctcatcggt aatgtcggct
     2701 tcatgtccaa gatcctgaac aagtctgatc acaaaatttg ccatagtcag gccaaagagg
     2761 ttttcggtgc cgatatgcta gacatggttc tgccaagact ggatggtttc gaacgttgtg
     2821 gggagacttt tgacacagtt atttcagcaa atccagcaac ctatgatgga agtacagagg
     2881 cactaaaaag cgcaaaatca gcagcggaag actttgcgaa ggcagtcttt gatcgcatcg
     2941 agttcattcg tactaacgga ggtatgtgat gtcgaatgag aaaagaaaaa ccatcggcag
     3001 acagttaaat actcaggcgt caatactcga aatggctgac accggtagaa gtcaggtatt
     3061 taccttaaaa accggcagga aggtaacgtt caggtttgtt cgggtgcctg catctgaagt
     3121 tgaaagtaag accttcgtaa accaggaaaa caatggaaga gatcaacttg cactgaccag
     3181 ggagtctctg aaatccatta tccagacgat taagtttcag cagttctttc cctgtattgg
     3241 tattaagcaa agtgaaagga ttgagatact ggatggttca agacggcgag cctcagcaat
     3301 ttttgtccgt acaggccttg atgtaatggt taccgaagaa catttatcag ctgatgaagc
     3361 tcgccaactg gctaaagata tccagacagc taaagaacat aatcttcggg agattggtct
     3421 gagattgatc gctcttaaag agtccggatt taatcaaaag gaaattgctg aactggaggg
     3481 attatctcag gctaaagtta ccagggcgct gcaggcggcg gccgtaccgc aagacttaat
     3541 ttctctgttc ccggttcagt cggagctatc gtttagtgat tataaacttc ttttagaagt
     3601 taatgaaaaa ctcggtgaaa agggattaac gcctgaagaa ctcattcagt ctgtatcagc
     3661 tcagctcgat gcaattttga gtgatggcga gcgaccagaa gacgaacaga aagccagtat
     3721 tctgaagctg atttctcagg catctcaggc attgatagat ccatctccca aggaaaagtc
     3781 agtggtttcc ccactctggt cttttgaaga aaaggacaag ttcgcgcgta agcgtgtgaa
     3841 agggcgcacg ctgacttatg agtttagccg tatgtcaaaa gtgattcagg atgaactgga
     3901 caaggctatc aacgaagtcc ttgacagaaa tttgagtcaa taatttcgcc atggcgattt
     3961 cacatctaac ttattgtaat taggcagttt aggttgagaa tttcacggtg aaatcgccat
     4021 ggtttcacgc cagtttcgct gcaggaatat ctgaccatcg tgtcgtataa gcaggagaaa
     4081 gcatctcccg tttcatctgc cattccgggg ccataccccg ccccgcaaac catactttac
     4141 ccagccctga gttgttgatc ccgtccagaa ccctcatcag ctcagcactg tgagggcgtg
     4201 gcgggcgttc gtcgaacagt tgcagctgcg aaactccgga gccggtgaag tcattcagca
     4261 taactccggc tttggcatac cggtgcccat ccctccagat acgctccaga gccgttgtag
     4321 cggctgcaat gatgtccctg gtgtcctgag tgggtgtaag aagtttttcc gtagccacgt
     4381 tgccgtagta aggctcttta atggcgaacg gagacgtttt gatgaaaacg gaaatatgcc
     4441 ggcaatactg gtgctcttta cgcagttttt cagaggcccg ctctgcgtgc tgacagatag
     4501 cctgacggag tgactcgtac tccgtgatct tcacgccaaa actgcggctg cagacaattt
     4561 gctgtttcgt cggaggggct tcctcaagcg aaaggcagct ttccccgttc agttcccgta
     4621 ccgttcgctc aaggacgaca gaaaaatttt tgcggatgaa ggccgggttc gtcagagcca
     4681 gatcgagcgc ggtttttatg cccagcacat ttagcttgcg tgcaatacgg ttacccaccc
     4741 cccagatttc ttcaaccggc tgcagtgaaa gcagtttccg cgtcctttgc ggatttcccc
     4801 tggtcagagc gagtacgcca tgaaactgtt tccactcttt tgaggcccac tgggctgatt
     4861 ttgcgagggt tttcgttggt ccggcgccca cgccaatggt caggcgggta cagtcataca
     4921 cctgctgacg cagctgccgg gcgaagtcct caagccccat acagtgctcc acgccggtca
     4981 ggtcgaggaa catctcatca attgaatact gttccaccct gggggccagt tcctccaggc
     5041 agttcatcac gcgcgccgat atcgaggcgt aaagttcata attacttgaa aacgcatata
     5101 ttttttccgg gtatctttcg ttttttatct gaaaccacgg agttcccatt ttgatccagg
     5161 gcttcgcctc ggcactgcga gcgattacat tcccgtcgtt gttgctcagg acgactatcg
     5221 gctttccttt caaatccggg cggaaaacac gttcacagct ggcatagaag ctgttcacat
     5281 cggccagggc aaacatcagt acatctccct cgggcggtgg atgatatgcg tgacgacgcc
     5341 aaagatatcc agctcgtcgg gatcaggata aatcggcgac caggaggcat tcatgggctg
     5401 cagcgtcagt cgcggcgtca gcagaagccg tttcaccgta aactccccct gcatgctggc
     5461 gacaacgata tcgccgtgcc gcggcttttc agcactgtcc acaaccagca gatcgccatt
     5521 gtacagactg ccgtcggcca tgctgtctcc gctggcacgc aggtagtacg tcgcgctcgg
     5581 atgccgtatg cagtaatcat ggagatccag atcggactcg acatagtcag cagcagggct
     5641 gggaaaaccg cagctggcca gatcggcaaa caatggatgg gcctgtggcg ggagttcttt
     5701 cccggtgctg aaaagttgta gtttcatctt tcctcctgac actctaattt tactggttat
     5761 acatacagtg tgcgccggga gaccggtaga gatcaagggg tgaaagtccc cgaccattga
     5821 aggaccagca atccacaagg tccccgagtc atgcgttgca taccgcgagg tatggggcga
     5881 agcgttgaca ggggtgttga caggccagcc attgagccac gaaatgtata ttaaattacc
     5941 gggtgccgac gttgtactgt taacggaagg caacatcata gggtgcgata ctgcgagtgc
     6001 cacatggacc cggcggggtc tgagaccctg gcatgtcaat acgatctcta cgcgggaacc
     6061 gggagatctc ccctctgacc atctgccagt gtcggagatg gcccgcaccg ggaagacgag
     6121 gagtcatagc cggtgatgta cggagaggag aagtcggact cgctcatagt agcggcgaag
     6181 caggcgaaca acccgaaagg agcggagtca gtggagcgaa ggagcggggc caaggggaac
     6241 gcggaacagc cacacatgcg ccggacacag agccgggaaa gcatgtcaca gaggctgtca
     6301 cgcgtgcggg aagctgcgaa gcagcggaag aaagaacggt ttacagcatt gttccacctg
     6361 ctgacagtcg aagcactgga agccgcattc ctctccctga gcaggaaagc ggccgccgga
     6421 gtggatggca tcaggtggat ggactacgcc ggaaacatga agaacaacat aacagatctg
     6481 caccggaggc tacatcaggg cagctacagg gcgcagcccg gcaggcgtca ctacatccca
     6541 aaagcggatg gaaaacaacg cccgctcggc atcgcctcgc tggaggacaa gatcgtccag
     6601 tatgcgctgg tgaaaatcct gaacgcagtc tatgaaaacg actttatggg gttctcatac
     6661 gggttcagac ccgggcgaag ccagcacgat gcactggacg cactggccac agggctggta
     6721 cgcactaacg taaactgggt actggatgcc gacatcagtc agttctttga cagggtgagc
     6781 cacgaatggc tgatcaggtt cacagagcat cggatcggcg accggagggt aatcaggctc
     6841 atacgtaagt ggctcacagc cgggggcact gttgcaaata gtcggtggtg ataaacttat
     6901 catccccttt tgctgatgga gctgcacatg aacccattca aaggccggca ttttcagcgt
     6961 gacatcattc tgtgggccgt acgctggtac tgcaaatacg gcatcagtta ccgtgagctg
     7021 caggagatgc tggctgaacg cggagtgaat gtcgatcact ccacgattta ccgctgggtt
     7081 cagcgttatg cgcctgaaat ggaaaaacgg ctgcgctggt actggcgtaa cccttccgat
     7141 ctttgcccgt ggcacatgga tgaaacctac gtgaaggtca atggccgctg ggcgtatctg
     7201 taccgggccg tcgacagccg gggccgcact gtcgattttt atctctcctc ccgtcgtaac
     7261 agcaaagctg cataccggtt tctgggtaaa atcctcaaca acgtgaagaa gtggcagatc
     7321 ccgcgattca tcaacacgga taaagcgccc gcctatggtc gcgcgcttgc tctgctcaaa
     7381 cgcgaaggcc ggtgcccgtc tgacgttgaa caccgacaga ttaagtaccg gaacaacgtg
     7441 attgaatgcg atcatggcaa actgaaacgg ataatcggcg ccacgctggg atttaaatcc
     7501 atgaagacgg cttacgccac catcaaaggt attgaggtga tgcgtgcatt acgcaaaggc
     7561 caggcctcag cattttatta tggtgatccc ctgggcgaaa tgcgcctggt aagcagagtt
     7621 tttgaaatgt aaggcctttg aataagacaa aaggctgcct catcgctaac tttgcaacag
     7681 tgccaggagg gccgtaaggt catgctaggt gacaaactcc tcttgccaaa ttacgcgccc
     7741 attccaagcg gctttgtcta tgtgctcgcg acaaagagca cggaccctat attgatgccc
     7801 ttcatgcaaa atctctacaa gataggtttc accgagggta ccgtcgaaga ccggataaag
     7861 cacgccgaga aagacaagac gttcctgcaa gccccggtta ggatcatcac gacattccag
     7921 tgtttcaaca tgaacaccca caaattggag accttggtgc acggttttct cgccaagcag
     7981 cgcctcgata tcaccttgaa gggggttgat ggcaccagct atgccccgag agagtggttc
     8041 catactccat tgacaaccat ccttgaagtt attcaccaca ttttggatgg aacaatctcg
     8101 cagtaccgca tggacaatac taccggtaag gttgttgcaa aaaaaacgac caataatgcg
     8161 taataatgcc aggcagcatt ggcacggacc tgctcatcgg cagccaaagg gcccgactgc
     8221 tctgccgctt gctgcatcca gtgcatggca ttggggtaat caggttggct ggccagacgt
     8281 ttggccaact catattgagc cttaccattg ccttgagtcg cggcattgga taactcggca
     8341 tcagtgagtg aagttgtgga agagcaggcc ggtcgccagc tgtaggagag gaataacgtt
     8401 tcatactgaa caatcaagca cccctgctca taccgtttta tatgaaacat gaccaaaatt
     8461 aaagattcat actaattgct actacgaagt ccgaatcgag cttcaaccga gtaataaagt
     8521 atcatcatgt acaggacctt aagcggcgag tccatttaaa acgccttcca aggtcctgtt
     8581 ctgtatcgac tttctctgct tggttcggca ggcgttcttg gccaaataat cggcagccca
     8641 ttccaatctt tcccttattt ctgtcagcgc cctatgggcc actgcttcca atagcggtag
     8701 ccaccacgtc gcactgttct tcgacgcttt cagcatcgat agcgccccac tcatcacact
     8761 ctgcgcgacc cgtctcttca tcaccagcga cagcaggctc gtccacacca acccctcggc
     8821 aatcgctttc tcgcccgtca caaacccctt gagccggttg tgcgatttcc actctttaaa
     8881 taacaactcc acctgccaac ggcagcgata caggctcatc acctgctctg ctgaccatgc
     8941 tgctcgcggt aggttcgtca tccacagaca gaaccgcttt tcctcagcaa accagcgccg
     9001 gatcaaccgg tactcgacct ggccggactt caccaccata tccagtacct cggcccgaca
     9061 gcgtcgccgt ccggcctctc tcagagatag tcccgccagc ttgggtactt cccgtccatc
     9121 accgcgccag gcttggatta tcttggggtt caggcttttc gtgccgcgca ccagataaaa
     9181 tccgccagcg tcgttcacct gctcaaacca agccctgtca atgtaacctg cgtcagccag
     9241 cagcaggcag ttggtcagcg tgtgggcttc aggcagaaat tgccgttccc ctgcggtatc
     9301 ggcagacaca ctcatgcaca acgggctctg ctccgacagt gacatggtca tatggcactc
     9361 gatagctgcc ggactgatgg tcttgaaccg gccgggaaaa tcagcagcaa ggcgccgatg
     9421 caccgcaaag gaggtgccat cgtgcagtaa cacctgcttg aacgcgccga gggaggctgc
     9481 tttgagttga tggtcgatac gcaaggcgat ggcccgctcg accagggctt tcataaacag
     9541 ggcaaagctc tctttgcgca gctgattgtg aaacggtttg taagaaacct gatgggtgtt
     9601 taccagttgc aaggcattga aatggcggtg taaaccggca atgtcattga cctggtcgcc
     9661 tcccatggcc cgcagcagtg caggtacgag catggctggg gtaatggcac gctgacgcag
     9721 acaaaacttg cagagccgag caatgcgctc gagtgcggcg ggagccaaga gttgctccag
     9781 atagtaatta gcgttgataa tagtcatagg cttcgcgcgt gttgattttg tttggcgata
     9841 aaatcagatc acaaacgaag ccttttttat atctatttca attggttgcc gctaaagatc
     9901 ctgtacatga gtgagggtta tggtggctat atgctggata ttgctattca gatgacagcc
     9961 atatggggaa gattacaggc gcctgaaata acagcagagt atggagtgac taccacggct
    10021 ggaggttggc acgggctgat cccctctccc tttgggagag ggttagggtg aggggagctg
    10081 gctgaccggg tgtagcaacc aggcggcatt acaccgctga atcttcagtt attgaaattc
    10141 cacgcgatcg gcagttcgac gtcgaagata agtgcatccc cgtcgaggcg aaaggccagg
    10201 ctggtctggt gctggtcgta ttcgttgata atcaggcagc tctcggcgaa gttggactcg
    10261 tagttgatat gggccactcc ttcacggccg tcagcgagtt cgatgctgag cacccgcagc
    10321 gggttctcct gactgaggtt gacccgggtg tcccccacgt ccaccagccg ttccagcaga
    10381 gggaagaaat cttgtctgtg ggtcgttatg gcctgggtga tggcctgctc cagctcagcc
    10441 tgggtggcga aggggccgcc gagtgggtag cgggtctgga tcctttcctg agtcattgcg
    10501 tttcctcctg aactgagatg tggcaacagt ttggccgctg cagtgacctg tcatgtacag
    10561 gatctttagc tacaaccaat tgaaatagat agaaaaaagg cttcgtttgt gatctgattt
    10621 aatcgcaaaa aaaaaccgac acgcccgaag ccatgactat tataaatgca acccagtacc
    10681 tcaagcaact tcatagctct tctgaactca accggatcgg taaatttacc ggtttttgtc
    10741 agcgactccg ggatatccag cctgcgagac tactcccggc tctgctctca gggcttggtt
    10801 gcgacaaggt ggatggtatt gctggtttgc atcgccattt caatgcgttg cagctccatg
    10861 atactgacca aatagcgtat aaaccctttc acaaccagtt acgcaagcag ggttttccct
    10921 tgttcatgcg cgcactggtt gaacgagcca tcgccttacg cctcaaggag tgtctaccgg
    10981 acgcccacgg actggcaggc tttgagcagg tactgctgca ggacgggtcg tcattcgcgt
    11041 tacatccgca attggcagaa catttcccgg gccgattcaa taagcacagc cccgctgcgg
    11101 taggggtcgg ttccggctga gggcgaaatg acaccctaag ctttcggttc cttgggccaa
    11161 agatattcgc cagtcagtag aatgtgcgcc cagcccaatg gggatatgtg gggaagaaat
    11221 tcagggggaa catccaaccc ttcgttccgc cgctccgtga cggcatgacc aagatggacg
    11281 gtattccagt aaatgatcac cgcagtcaat aaattgagcc cagcgattcg gtagtgctgc
    11341 ccctctgtcg tgcgatcgcg aatttccccc tgcctcccga tacggagcgc atttttgagc
    11401 gcatggtggg cctctccctt gttaagaccg atctgagcac gccgctgcat gtccgtatcc
    11461 aggatccact caataatgaa aagggtccgt tcaatacgac caacttcacg aagcgcaact
    11521 gcaaggttgt tttgtcgtgg gtaagaagcg agcttgcgca ggagttggct gggcctgatt
    11581 ttgccagcgg tcatcgtcgc ggcacaacgg aaaatatcag gccagttcgc aacgataaga
    11641 tcctcccggg cttttccacc taccaacttg cgtaactccc tgggggtcgt atcgggatta
    11701 aatacgtaca accgcttcga tggcagatcc ctgattcgca gaacgagatt gtagccgagc
    11761 aggctactgg ctccgaacaa atggtcggtg aatcctgctg tatcggcata ctgttcgcga
    11821 acatggcgac cgacctcgtt catcagtagt ccatcgagaa tatacggtgc ctcgctcacg
    11881 gtcgccggga tcgactgaca agcgaatggc gcgaactggt cgcttacgtg agtatacgct
    11941 ttgaggccgg gaacagaacc atatttggca ttgaccatgt tcatgacttc gccatgccgc
    12001 gctgtcggga aaaactgacc atcgctcgat gctgacgtgc ccatccccca gacgcgtgac
    12061 atcggcagtt taccctgcgc ggccaccaca attgccaatg cctggttcat ggcttcgctt
    12121 tcaacatgcc agcgggcaag gcgtgagagc tgccagtaat catgcgtgtt tgtagcttcc
    12181 gccatcttac gcaggcccag attgagccct tcagcgagca ggacgttgag cagaccgatc
    12241 cggtcgcgac atggagcccc ggttctcaga tgggtaaacg catctgtgaa accaagggct
    12301 gcatcaactt caagcagcat gtcggtaatc cgaacggacg gcattcggcg atacagatcc
    12361 agtatgagtg cctcggcacc atccggcacg tctgctgtca acctgtcgat ccgcaacgtt
    12421 ccatcttcta tgctaccgtg cggaatagtg ccgttacggg cagcccgggc cagccgctta
    12481 agagcgatcg tgagtcgcgc ctttctgtct gccagccaat cctgtgggtt ggaaggcacg
    12541 gccagttttg cattttcctg cgccgcgatc atcggcacca gtacctgctt gaggtcacca
    12601 tagcggcgcg aatgagcgag ccagacatct ccggaacgaa aagcatcccg gaggtgaaag
    12661 agtaccgcca cttcccaaag acgggtatct cctttttcct gagctcgtaa atgacggttc
    12721 catttggagc tgggccgcag gaaacgcctt tctggcgatg caacaccttt catctctccg
    12781 atcgacaaag ctgctgctac caatggtccg gcgaccggcg cggcttcgag cttcagacag
    12841 cgcaacatgc ggggcgcata acgacgaaag cgatggtatc cctgcccgac atatgcaaga
    12901 ggctcatcgg ctagcgtgtt gctgagttga gtccctgtcg ctaccagttg agcgagccgg
    12961 tcccatgcaa ccgaactggc gacagccatc tccagcgggg ttccgtcact gcgggcctca
    13021 agcaacgaag ctcccagcgc ggtgaaggta cggatcgtat ccgtgagtgt ggctttagag
    13081 ccggaaattg tttcgtcatg ctggcgcttc gcttcccgcc aggtttttcc tacgatcctg
    13141 tcatgggttt cgactatggc atcagcaatc gccgcttccc actccacaac acagacggca
    13201 aggatcgccc agcggcggtc cgaagtgatg tcacgcaaac cgtcggtgaa gtagcgttca
    13261 ccctgccgac gcagccgggc aatgcgatgg gcaggtatgc tggccaaagc actatgattg
    13321 atattcaggg tacgcagaaa ttcgagcctg tcgagcaaac ggttagcagc agccgagttg
    13381 ttaccaacct cgaagttgcg aagccagatg aaacgactga tattgccggc gagcatttca
    13441 ctcagaagtt tgtccaggtg atcgcgaaca tccgctgtta aattttccgc aatccgcgtt
    13501 tcaatccgcc actcagcggc gaccagagca tccgcgcaca agcgctcgat tgtcgatact
    13561 gcgggcagaa tggtggaagt ttcccgacac cgcacaataa aacgatgagc aagatcctcg
    13621 tttgatctgg catcttcggc ctggccgaaa gtccactccc gcagatcacg ggcaccacgg
    13681 cccgtgaagg tcttgtagcc gtaaatttcg cgcagcgtgt ccatgtgctg ctgacgggtt
    13741 tggcgccgtg tggcataagt gagaagcgca tcagccggaa ctccaagctg agcaccgacg
    13801 aaggaaagga cttcacgcgg gatcatctca ccaggagcca gtgcacggcc cggatatcgt
    13861 aaggcacaaa gttgcagggc aaagccaatc ctgttttccg gtctgcggcg ctgcctaatg
    13921 ttttccaggt catcatcgcc cagcgtgtag aacttcagta gcgacagttc gtccgtgggc
    13981 agatcgaaca gcgctgctcg ctgccgttcg gtgaaaatat ggcgtcgtga catacaaatt
    14041 cgggcactgt tgcaaatagt cggtggtgat aaacttatca tccccttttg ctgatggagc
    14101 tgcacatgaa cccattcaaa ggccggcatt ttcagcgtga catcattctg tgggccgtac
    14161 gctggtactg caaatacggc atcagttacc gtgagctgca ggagatgctg gctgaacgcg
    14221 gagtgaatgt cgatcactcc acgatttacc gctgggttca gcgttatgcg cctgaaatgg
    14281 aaaaacggct gcgctggtac tggcgtaacc cttccgatct ttgcccgtgg cacatggatg
    14341 aaacctacgt gaaggtcaat ggccgctggg cgtatctgta ccgggccgtc gacagccggg
    14401 gccgcactgt cgatttttat ctctcctccc gtcgtaacag caaagctgca taccggtttc
    14461 tgggtaaaat cctcaacaac gtgaagaagt ggcagatccc gcgattcatc aacacggata
    14521 aagcgcccgc ctatggtcgc gcgcttgctc tgctcaaacg cgaaggccgg tgcccgtctg
    14581 acgttgaaca ccgacagatt aagtaccgga acaacgtgat tgaatgcgat catggcaaac
    14641 tgaaacggat aatcggcgcc acgctgggat ttaaatccat gaagacggct tacgccacca
    14701 tcaaaggtat tgaggtgatg cgtgcactac gcaaaggcca ggcctcagca ttttattatg
    14761 gtgatcccct gggcgaaatg cgcctggtaa gcagagtttt tgaaatgtaa ggcctttgaa
    14821 taagacaaaa ggctgcctca tcgctaactt tgcaacagtg ccaggcaggc ttatcttgga
    14881 caagaagatc gcttggcctc gcgcgcagat cagttggaag aatttgttca ctacgtgaaa
    14941 ggcgagatca ccaaggtagt cggcaaataa tgtctaaaac aaagttatgc acctattaag
    15001 cgcacagcgg agcaatgaag gataccttga tgaaaaaaat tttgctgctg catatgttgg
    15061 tgttcgtttc cgccactctc ccaatcagtt ccgtggcttc tgatgaggtt gaaacgctta
    15121 aatgcaccat catcgcagac gccattaccg gaaatacctt atatgagacc ggagaatgtg
    15181 cccgtcgtgt gtctccgtgc tcgtctttta aacttccatt ggcaatcatg gggtttgata
    15241 gtggaatctt gcagtcgcca aaatcaccta cgtgggaatt gaagccggaa tacaacccgt
    15301 ctccgagaga tcgcacatac aaacaagtct atccggcgct atggcaaagc gactctgttg
    15361 tctagttctc gcagcaatta acaagccgtc tgggagttga tcggttcacg gaatacgtaa
    15421 agaaatttga gtacggtaat caagatgttt ccggtgactc ggggaagcat aacggcttga
    15481 cccagtcatg gctgatgtcg tcgctcacca tatctcccaa ggagcaaatt cagtttcttc
    15541 tacgctttgt cgcgcataag ctgcctgtat ccgaagcggc ttatgacatg gcgtatgcca
    15601 caatcccgca gtaccaggca gccgaaggat gggctgtaca tggaaaaagc ggcagcggct
    15661 ggcttcggga caataacggc aagataaatg aaagtcgtcc gcagggctgg ttcgtgggct
    15721 gggctgaaaa aaacggacgg caagttgttt tcgcccgatt ggaaatagga aaggaaaagt
    15781 ccgatattcc cggcgggtct aaagcacgag aggatattct cgtggaatta cccgtgttga
    15841 tgggtaacaa atgatatgtg gcgtcatcga gagcagatgc ataaccctgc gctcgagcgg
    15901 acctcgcgca taaagccgcg cgagtccgct caccttgaac gttagatgca ctaagcacat
    15961 aattgctcac agccaaacta tcaggtcaag tctgctttta ttatttttaa gcgtgcataa
    16021 taagccctac acaaattggg agatatatca tgaaaagagt ttgatgctca gggtgtagcg
    16081 gttcggttta ttgacgacgg gatcagtacc gacggtgata tggggcaaat ggtggtcacc
    16141 atcctgtcgg ctgtggcaca ggctgaacgc cggaggatcc tagagcgcac gaatgagggc
    16201 cgacaggaag caaagctgaa aggaatcaaa tttggccgca ggcgtaccgt ggacaggaac
    16261 gtcgtgctga cgcttcatca gaagggcact ggtgcaacgg aaattgctca tcagctcagt
    16321 attgcccgct ccacggttta taaaattctt gaagacgaaa gggcctcgtg atacgcctat
    16381 ttttataggt taatgtcatg ataataatgg tttcttagac gtcaggtggc acttttcggg
    16441 gaaatgtgcg cggaacccct atttgtttat ttttctaaat acattcaaat atgtatccgc
    16501 tcatgagaca ataaccctga taaatgcttc aataatattg aaaaaggaag agtatgagta
    16561 ttcaacattt ccgtgtcgcc cttattccct tttttgcggc attttgcctt cctgtttttg
    16621 ctcacccaga aacgctggtg aaagtaaaag atgctgaaga tcagttgggt gcacgagtgg
    16681 gttacatcga actggatctc aacagcggta agatccttga gagttttcgc cccgaagaac
    16741 gttttccaat gatgagcact tttaaagttc tgctatgtgg cgcggtatta tcccgtgttg
    16801 acgccgggca agagcaactc ggtcgccgca tacactattc tcagaatgac ttggttgagt
    16861 actcaccagt cacagaaaag catcttacgg atggcatgac agtaagagaa ttatgcagtg
    16921 ctgccataac catgagtgat aacactgctg ccaacttact tctgacaacg atcggaggac
    16981 cgaaggagct aaccgctttt ttgcacaaca tgggggatca tgtaactcgc cttgatcgtt
    17041 gggaaccgga gctgaatgaa gccataccaa acgacgagcg tgacaccacg atgcctgcag
    17101 caatggcaac aacgttgcgc aaactattaa ctggcgaact acttactcta gcttcccggc
    17161 aacaattaat agactggatg gaggcggata aagttgcagg accacttctg cgctcggccc
    17221 ttccggctgg ctggtttatt gctgataaat ctggagccgg tgagcgtggg tctcgcggta
    17281 tcattgcagc actggggcca gatggtaagc cctcccgtat cgtagttatc tacacgacgg
    17341 ggagtcaggc aactatggat gaacgaaata gacagatcgc tgagataggt gcctcactga
    17401 ttaagcattg gtaactgtca gaccaagttt actcatatat actttagatt gatttaaaac
    17461 ttcattttta atttaaaagg atctaggtga agatcctttt tgataatctc atgaccaaaa
    17521 tcccttaacg tgagttttcg ttccactgag cgtcagaccc cttgttgagg attttaccca
    17581 gaaaccggta tgcagctttg ctgttacgac gggaggagag ataaaaatcg acagtgcggc
    17641 cccggctgtc gacggcccgg tacagatacg cccagcggcc attgaccttc acgtaggttt
    17701 catccatgtg ccacgggcaa agatcggaag ggttacgcca gtaccagcgc agccgttttt
    17761 ccatttcagg cgcataacgc tgaacccagc ggtaaatcgt ggagtgatcg acattcactc
    17821 cgcgttcagc cagcatctcc tgcagctcac ggtaactgat gccgtatttg cagtaccagc
    17881 gtacggccca cagaatgatg tcacgctgaa aatgccggcc tttgaatggg ttcatgtgca
    17941 gctccatcag caaaagggga tgataagttt atcaccaccg actatttgca acagtgccca
    18001 tcggcgtagt agtggatgtg gtcgatgaca aagccggtgc gggtcagcgt gcgccggagg
    18061 atcggcagaa aatcgaccag gaacgaagta gcgcgtgtga cgacggccgg tacgccgaca
    18121 cgcgccacgg cctcggccca gcgcgcggcc ggcggttgga gcaggccgtt gtgcaccgaa
    18181 ccgtggtagg tgccgaccgc caatgtgagc cagcgctcta gctcgcgcag cgtcagggcg
    18241 gccttgtttt cggaatcgta gtcgccgcgc tggtcagggt tggagaaggt cgttcccggc
    18301 agttcgtcgt gaatcatctg catcgccgtg ccgatgatcc gttccacgat gccgccatag
    18361 tgcggctgtc ccagcgggcg atagtccagc cggatgccat gctgctcgca accccggcgc
    18421 agggcctcgc tcttgaactc ggccgcgttg tctaggtaga gcagcaaggg cttgccgctc
    18481 atctgccaat ccatttccac gttcagtcct tccagccaag ggcgcttgtc gcaggcgata
    18541 tgcacgaggc acaggccaac cgaaacggca gacggcgctt ccagcgtgac gaccatgccg
    18601 agcacgcagc gggtgaacac gtcgatggcg agggtcaggt acgggcggcc aataggttgc
    18661 cggtcgcggt catcgaccac gatcaggtcg atgaccgtat ggtctatctg cacctgctcc
    18721 agcggcgcgg tcacggcagg aggctcgccg cccacacctt gtaggtcacg agcggcatcc
    18781 tggccttccc gccggcggat gaccttgcgc gggtcaaggc tagcgatccg taaggccacg
    18841 gtattgcgcg ccggcactcg cagtttttga gccttgcaca cctgagtgac ttcgcggtga
    18901 aaggccgcta ggctgcgctt ctgcttggtc aggaaccgct tttgcagtag ctcgtggatg
    18961 acgcgctcga ccggttccgg caagcgcccc ttacctttac ctccaccgga ctggccgggc
    19021 accagatccg tcacgaggcc gctgccttgc cgggcacgcc ggatcagaac gtatacctgg
    19081 cgccgagaca agcccagcgc ctgagccgcc atatcggccg cttcgtgccc gaccgtctcc
    19141 gactgcgcca acggactgat gatctccgca cgacggcgcg cacgctccca agcctcatca
    19201 ggcagagtgg ccacgccttg ttctggaatc cgtggggtgt ccgtcgccat gctcacctcg
    19261 ctttggtgca cacgagtatt gagcatagtc gagattggtg cagatcactt ctgatattga
    19321 actgtcagga gctggctgca caacagccat tacgcccaat caactggtgc agtcgtcttc
    19381 tgaaaatgac atccatgccc agcccgtgcg cgagctggat caccgcccgc acgatagttt
    19441 ggtcacgggc atcatccggg agcctggcga caaaggattg gtcgattttc aatgtggtga
    19501 tggggcagca tttcagatgt tgcaggcagg aatagccggt gccgaagtcg tcggcggcga
    19561 agcgcacgcc gatggcgcgc aaggcgtcga aactggcgaa cagggctgga ttgccgaatg
    19621 cgaccgattc ggtcagttcg atctccagaa gctcggcggg cagggccata tcggccagca
    19681 cccgctttac ctcgtcgtcg aacgttggcc caacctggct ggcggacaca ttgatggcaa
    19741 gacggaacgg ttgccatgcc ggtccttgcc acttgtgcat ctggcgacag gcctcgccca
    19801 gcacccacgc gcctatttcc ggcatcaggc cgaacgactc ggccagcggc aggaactggc
    19861 cgggcggcaa caggccaagc ctcggatgcc gccagcgcat caacgcttcc gcgccagcga
    19921 tccggtgatc gcgcagatcg accagcggct ggtaatgcag gtcaagctgt ccgcgcgccg
    19981 ccgcctgcgc caactcggcc gccgtccatc cggcgggctg cgaactcgtc atgatccgcc
    20041 ccggaaggcg cgcagcagcc gcgttacggc cagaacgaac aagccggtca gcgcgagcgc
    20101 ggcaacaccc caatgctcgc caaggaaggc accggcggtc gtcccggcca gcacggcggc
    20161 gagaatcggc agatggcagg ggcaggtcaa cacggccagc gcaccccaca ggtagccgga
    20221 aacgggttgg cgcgtctcgg gcggcagttt gtcaggggcg ttcacggcaa tgcctcctcg
    20281 tgcgcccgct cggctggcat ggaggccagt tgcgcgtcca gatgggccaa cgccgcgcgc
    20341 cgccgctcga ccaactggcg cagcacggca agctgcgctg cggcttgtgc gccgtccgct
    20401 gcgtcgagcg cacggcacag ccgcgccagg gcatccaggc cgatacccgc ctcgaaggcc
    20461 gcgcgcacga agcacagccg ttgcaaggcc gcatcgtcga acacgccgta gccgcccgtg
    20521 gtgcaggcca ccggccgtaa caagccgcgc accaggtagt cgcgcacgat atgtacgctc
    20581 accccagcgt tatgggccag ttgcgatacc gtgtaggcgc tcatcgcaca cctccttgtc
    20641 ctcacccggc gcagcaggaa agctgcttca catccttgtt gaaggtctgc gccgcgagct
    20701 tcaacccttc gaccatcgtc aggtagggga acaactggtc ggccagttcc tgcaccgtca
    20761 tccggttgcg aatcgccagt gcggccgtct ggatcagttc gcccgcttcc ggggccactg
    20821 cctgcacgcc gatcagtcgt ccgctgcctt cttcaaccac cagtttgatg aagccgcgcg
    20881 tgtcgaagtt ggcgagcgcg cgcggcacgt tgtccagcgt tagcgtgcga ctatcagttt
    20941 tgatgccgtc atggtgcgct tccgcctcgc tgtagcctac ggtcgccact tgcgggtcgg
    21001 tgaacaccac ggccggcatc gcggtcaggt tcagggccgc gtcaccgccg gtcatgttga
    21061 tcgcggcgcg agtgccggcc gctgccgcca catagacgaa ctgcggctgg tcggtgcagt
    21121 cgcctgcggc gtagatgtgt tccacgcttg tacgcatgcc ggggtcgatg acgatagcgc
    21181 cttgcggggt gagcgtgacg cccgtcgcat ccagtgccag cttgcgtgtg ttgggcgcgc
    21241 ggccggtggc gaccagcagc ttgtcggcgc gcagttcgcc gtgcgccgtg gtgagcacga
    21301 attcgccgtc cccttcacca ttgatatacg cgacctggct ggcctgggtg tgttccctca
    21361 cctcgatgcc ctccatgcgg aatgcggccg tgacggcttc gcctatagct gggtcttcgc
    21421 ggaagaacag cgtgctgcga gccaggatcg tcaccttcgc tccgagtcgg gcgaacgcct
    21481 gcgccagctc cagcgccacc actgatgagc caatcacggc caggcgctta ggaatcgtct
    21541 cgctgaccag cgcttcagtg gaagtccagt acggagtgtc tttcaggccg ggaatcggcg
    21601 gcacggccgg gctcgcgccg gtggcgatca ggcagcggtc gaatgccacc acgcgctcgc
    21661 cgccgtcgtt gagttgcacg atcaggttgc gattgtcctt aaagcgggcg gagccgtgca
    21721 gcacagtgat cgccggattg ccctccaaga tgccttcgta cttggcgtgg cgcagttcat
    21781 cgacgcgggc ctgctgctgg gccagcagcg ccgtgcgctg gatggtcggc gtggtagcgg
    21841 cgatgccgcc atcgaacggg ctttcccggc gcagatgggc gatatgggcg gcgcggatca
    21901 tgatcttgga cggcacacaa ccgacattga cgcaggtgcc gccgatggtg ccgcgctcga
    21961 tcagcgtgac acgtgcgcct tgctcgacgg ccttcagcgc cgctgccatc gcggccccgc
    22021 cgctgccgat gacggcgata tgcaatgcgc cgctgctacc cgtcttgtcg tttctgccca
    22081 gcagatcgcg catcttgtcg agcaatccgc ccggcgtcga aactgagggg gcatcggcca
    22141 gcgtggcccg ataaccgagt ccagctacag cggccgtcag cgcgtcgggt gacgtgccga
    22201 cctcaatggc gagcttggcg ctgcccttgg cgtaggagac atccgctgat tgcacgccgg
    22261 gcactttctc cagggcgtcc ttgacatgca ctgcgcacga gtcgcaagtc atgccggtga
    22321 ttttgagagt gctcatacca tcgttcctta ttcgtgtggg ccgccgtgtc gcacggtcag
    22381 ccgtctttca caagcgcttg gcggggagtt cgcagccgtc cggtccgcaa cggcgatgcg
    22441 ccggcgacac gaagtcccag atcgacaccc caatcatcaa ggccaggccg acgtacatca
    22501 ggttcgccgt ccaccagttg ccgagcagcc agaccgtggc cgcaaacacg atggccgggc
    22561 cgatcatgcc gagcagactg cgcagccatt gccgatgact gaaccaaccc agcgcgttcg
    22621 ccaggaaggc cagcgcggca aacagcggca gcaggcggct gatgaacagt ccctcgtact
    22681 ggctcaagaa gcccagcccg atggccgcgc cgaagctggc gagggctgga aagcaggcgg
    22741 cgcagcccat cgcggaaacg acgctgccga gcgcgccggt tttatcggca atgcgtgtca
    22801 tcagtcccat gaagcggctc tcgctgttgt cgttggcttg ctggctcact gcttgacgct
    22861 ggacggatag ccggcgtctg cggtggcctt ggtcagcttc tgtacgctgg ccttggtgtc
    22921 gtcaaaagtg acgacggcct cgcgcttctc gaagccggta atgactccaa tttactgata
    22981 gtgttttatg ttcagatagt gcccgatgac tttgtcatgc agctccaccg attttgagaa
    23041 cgacagggac ttcctgccca gccttgccag atgctgtctc agattcaggt tgtgtcgctc
    23101 aattcgctgc gtgtaacgct tactgatgac gtgcagtttt cccttcagac gtgactcata
    23161 catcggccag ccgtccgtca tccataccac cacgtcaaaa actgacagca ggctcagaag
    23221 acgctccagt gtggccatag tgcgttcacc gaaaacgtgg gctaccaccg ccctgcgtat
    23281 cctgtcatac gcgtaaaaca gccagcgctg acgtgatttt gcaccgacgt agccccattg
    23341 ctcgtccatc tccgcacaga caatgacatc actgcccggc tgtatccggg aggttactga
    23401 ctgcggcctg agttttttaa atggcgcaaa atggtgttga ggcccacgcc cattagtcgt
    23461 gcggtggcac ggcaaccgac gccgttcata gccatatcaa tgattttctg gtgtgtaccg
    23521 ggctgagaag cggcataagt gaaggtgagc tgccatgttt tacggcagtg agagcagaga
    23581 taacgttgat gcccggcagt acttttgcca ttacgcatca cgccttcagt agcggaacag
    23641 gagggacagc agacggagac tgaagccacg ggagcacctc aaaaacacca ttatacacta
    23701 aatcagcaag ttggtagcat cacccgcacg ccaaactgat acgtttccag cgtgtcgttt
    23761 atggctgaca gatgccgggt gcagaagtgc attttctgtt gccggtaact gttttcaagc
    23821 cggtaccgat cggccaccgg cacattgacg ctgtaaactg tgcgcgtata ttcctgtgcg
    23881 gcgtgctcgt tatcgatgcg tgcactgtct aagagcagat ggcgcagata gcgtctgaag
    23941 ctggcgaaat gaccaccgga gaaggtgctg aaccgcacgg aatagtattc atagggaaaa
    24001 ttatcgggat cctgctgtag tacattgtga atatcctggc cgtattcctc cgtcattggt
    24061 gcaatacgca ttctgagacc atccgcattg atacccgcca gattttgcct gccgttcagg
    24121 tcaggatctc ccccattact caggaaaacg tcagctgtca gcacgggtaa ctgatcggcg
    24181 cggcgctcac cttcctgaaa ctgccttact gctgactggg acaggagcga ttccacaccc
    24241 aatgcctcga cccggtgccg gctgtcactc agcacaaggt caagggccag cagaatcgtg
    24301 cttttcccgg actcattgtc cccgaccaga atgttacggt catgagtgaa gcgcaggtcc
    24361 agttccggaa actttttaaa gttttgcagc ataagccgcg tgatcagagg catcttttat
    24421 tcctttatat accgctgact gaaagagtgt ccggctgcgc cagaccgcct gttttgtttt
    24481 acagcgttat cttacccagt cttccagcac aagacccggt acccgctcaa attcccgcgt
    24541 attattcgtc accagcacgg caccggcggc gatggcgtgc ccggcaatgg ccgtgtcgtt
    24601 cgggccgatc ggcgtcccgg ccattcgcag cgccacctta atctccgtgg tggcgtccac
    24661 cgcagcgcga tcccagggca ggatggcatc gaggcgggcg cagaacgcgt cgaccagctc
    24721 gacgtggcgc ggggaggcct tcgggccggt ggccccgaag cgcatttcag aataagtgat
    24781 ggccgagaca acgatgcgct ggccgcgcag caccgcctgc tccaggcgct tcaggacggc
    24841 ttccggctgc tcgcgcatga tgaacgagca gatacaggtg tcgagcatat aggtcttgtt
    24901 cacaggttaa atcgtccttc gtcgctgaca acgtcctcgc gctccgccat aaagtccggg
    24961 tctgccttct cgaactgcgc gaacgagccc caggtcggcc ggacgggacg caaaataatg
    25021 ctgtcccctt cccggacgat ctccagctcg ctcactccct caaaatccag atcgcggggc
    25081 agacgaatgg cgcggttatt gccgttttta aaaatggata cagttctcat catttcctcc
    25141 tggccgaccg gcctgtatga ctatgttcag tatatgcaga tgcaaagcat atgtatagtc
    25201 atagcatatg cagatggtaa gtatatgcgt atgccacacc tatgcagatg cccggcatat
    25261 ggatatgttg aacctatgtt gtattctctc ttttcccggt cagatccgaa aaaaggtaga
    25321 gtcggatctt tgcccgtgaa tctctcgaga gagatgtatg gataacttca agattggact
    25381 tttagaatgg ttttagtgca ggttgacagg cagctatgag cgaggagcag acattcgcaa
    25441 ctgtaatcgc cattgataat gctctactca ccctcccctg tgttaaccga cagggagcag
    25501 gtcaagacct cgggagggag aggtggaatt ttattgtttg gttggtcgtt gatatcctac
    25561 actgcgaccc ggattatcaa cgacccgccg aaagatatgc tcgaaaacag atgtaaaaag
    25621 cctcctgctg gctgcttgta ttaaactgtt ttttcgattc ccagcatgcg cacctcatgt
    25681 tccgacatcc agttatccgt agcctccgta tgcccgtctg attcagtaaa cacgataatt
    25741 tcatgagcgg ggttgaggct cgcctgatat tcaacagatt tcagcagttc agggcttggg
    25801 aacatcaata aatacactgc ttccggcaga taactcttat tcagggttag gggcgaatat
    25861 aagctcaatt tccgtccgtt aacggagata acctgatttg acttaagttt attaacaact
    25921 tttttttcaa agatgcgttc tagtatttga tcgcagtgtg atttgttgtt cacgcacaga
    25981 taaacctcac actgatggtg ttcggctcgg tcaatagcat attttaagat gcttccgtgc
    26041 agcccgttca taagctcaga aaactcacgc tgcaatatca cccggtcagt cattttagtt
    26101 ccttttgatg aatgaatttc gccatttatt atatcggtaa cgcccgggtc agcacagtgc
    26161 ggctgggcgt cagagtgcat ggttcatgca taataggcgt tttacctaat actcgcaaaa
    26221 agggagcaaa aaaaactgcc tcgcagtggt attaatgcaa agtacaatcg ctagtgtccg
    26281 ctcctggcac aaagcggccc tcaacagcgt ccacactgtc agaggtcagg acggatgttc
    26341 ttgcagaaaa atgatgcgtt ccgttttgtg gctgattcgc cgtcaggatg acttgtccac
    26401 tcagagcaac aatcagcacc ttttccttcc aaaaagacaa caatacacca ttcgcaacaa
    26461 tccgccacct tttgtgctca tcatgcaata atccttcttc attcctcctg agatccgaaa
    26521 aaagtaagtt ccggatctga ttcagccccg ccggcgcgca gcggcccgga aacacaagat
    26581 gtagcggtgt ttccagctgt cagtgaccat atatgttgtg cccctcccct gccccgtgac
    26641 cggccgctca ccaccctgaa agggcgctgt ggttattccg tgtgcgtggt acacttccgg
    26701 aaactgtgga ataacataaa agtcggatcc ggccagagcg gccgtcaggt aatttaatta
    26761 cgttgttata tggctgctta ttattttagt atgtgaaaat cactctcgtg aaagtcactg
    26821 tcgcgacaga gtggcactca tctgacgatg attgaggtgt ggtaaaattg cacggctaac
    26881 tattcaactg aggaaaggac atgtttactg cattcaatga gagaaatgat ttcagttatg
    26941 cttttgaaaa aatccgtaat gcgatttccg cgccaggaga aaataatctt tatgctgcaa
    27001 cagaattagg tcttggcatt ctgctccgta aatacgagca gtttcgccag gaactggatg
    27061 cggccggtga gctgggaaac tgggaatatg atctcgatac ctacaatcac tgtattgcgg
    27121 tgctgcaacg ttacttcacc ggcaatccat ccggactgac agaacgtgat gcccggattt
    27181 acagccatta cctgcagact gagcacaaaa ggtttgtgaa actggctgaa gagctggctg
    27241 ccggccgctg actacggaca gagggcggga tttctcagga atataaaggg gtaaatgatc
    27301 aatgactgat atacaggccg caactgagag tatagttgct gcgacatccc atccggtttc
    27361 cgtacagctg attaatcaag gggcggggat ctggggaaac gtggcaaccg ggcttatcac
    27421 tggcctgctt actgggggta taacactcac tggcatctgg ctgacacatt atttcacgct
    27481 taagcgtgag agacaggcgt cagaagataa aatgaaaaag gaactgcatt acattgccac
    27541 cgagttggta ttcatgcttg aacggtatgc tgagggttgt ttccgggttg tgacggatga
    27601 cggccaggat gatgatgccc cccagcctga gagaaaagct gtcacgaatt accctgaact
    27661 gaatctgatc gatgtctccg gtgactggcg gactttagag ccacgtctta tgtatcgcat
    27721 ccgtgaactg ccggtgctcc aggatgaggc ccacagggca attgcatatg ccgccgaata
    27781 ctccgaccct ccttggcata aggactattt cagggaacgg cagtatcagt tcacgcgctt
    27841 gggcatcaac gctgtcattc ttgccgtccg tctgcgcaag gcaaccggga tgcccgaaac
    27901 acgtcttaca ggtcatgatg aatggtctgc agtttccgtg tttcgtaaag tctggaggcg
    27961 cgaaagagcc ctgcgcgctg ctgaagctac ccgcaacagg gagtggaatc aattagtgat
    28021 acctgatgga atgtcaaacc aatgagcggc ctcttatcat attctcaccc gcagcagccg
    28081 gcgcaaatgc cggtggccat tgactatccc gccgcgctgg ccctgcgcca gatggcgctc
    28141 gttcaagatg aactaccgaa atacctgctg gcaccggaag tcagcgccct gctccattat
    28201 gtgcccgatt tgcaccgcaa gatgctgctg gcaaccctct ggaacaccgg cgcacgtatc
    28261 aacgaggcgc tggcgctgac ccggggggat ttttcgctgg tgccaccgta tccgttcgtg
    28321 cagctggcca cgcttaagca gcgcaccgaa aaagcggcca ggacagccgg ccgagctccc
    28381 gccggtagcc aggctcatcg tctggttccg ctttccgatc accactacgt cagccagctg
    28441 cagatgatgg tggccaccct gaaaattccg ctggaaagac gcaacaagcg taccggcaga
    28501 acagagaaag cccgcatctg ggacatcacc gaccggacag tacggacctg gattggcgaa
    28561 gcggttgaag cggccgccgt cgacggggtg acattctcgg tgccggtcac cccgcatacg
    28621 ttccgccact cctacgcgat gcatatgctg tatgccggca taccactgaa ggttttgcag
    28681 agcctgatgg gccacaaatc gattagctcg acggaagtct atacgaaggt gttcgcactt
    28741 gatgttgctg cgcggcatcg agttcagttt cagatgcccg aagcggatgc ggtagccatg
    28801 ctgaaaggga atatttaagt acttaggaga atgatgctgg cgaacgtcct gctcgccggg
    28861 gaggtctgtc agacgttatc tggaccagct gacgggaata tctgctctgt attcctcata
    28921 ctgctcatag atcgcatgct gaagcatcgt aatacgttct gacaacctgt tggcgtccga
    28981 catatgccgc cattccccct caatagtggt tttctgtcca tccgggagat tgagcgtgat
    29041 caataccttt gtatcacgaa taatcacccc gtcagtgaaa gaattaagac cactccttac
    29101 ggtattatct atctgtatag tttcaagttt catcttgtta cctcctgttg accggatccc
    29161 aagcatagat atctgaattc aaattgccta gtgaaatgtc tggatatgcc gcatttttcc
    29221 ccttatacag cgaagctggc caaaggccag cccgcttgga tttatcgctt ttgccagtag
    29281 atcagcatgg caaggaacag gattgttgcc ccctgagaag cggtcaggaa agtttccagc
    29341 aatgacatta tcgtaaaact ccgcattatt aatttcaggt gtgtgattca ggggccttag
    29401 tccccctttt acaggacgta gtgttctgtc acgacggaag ccagggttaa taaaaacgat
    29461 tcgaatatgt ctgcagggac gatagaaatc ttcgtgcggg ttgtctcgct gtagccggct
    29521 ctggagagcg actcggggga ggagtagtat cttccggcca cggatatgat cgagccagca
    29581 gtgctcgccg cagtcgagcg acagggcgaa gccccgagtg agcgaggaag caccagggaa
    29641 caaaacttat aaattctgct tacgctcaat gcctgaaaaa tcacctctcc tcggggttat
    29701 ccacttatcc acgggcatat ttttataaag tactttttta ttctttttct ttattttaca
    29761 tcttttaggg agcctgaaag ccgcgtacag tgcggcctga gagggggcct gtatgggcaa
    29821 ctggtaaaca taatatggga aattaatcac gtatcagtgg gttttgtgtc aacaagctat
    29881 gggatacgca tcaacaagct atgggaaaga ggtcaagttc agttctcaat tatccacttg
    29941 tggataaagt gcagattttt ccggtggata agtatcgcga tagcttgcaa tttctgtttt
    30001 cactgtcatt atgggtgggt aaaaatttac ccataggcat tgaa
//
