LOCUS       CP063650               15826 bp    DNA     circular BCT 04-APR-2022
DEFINITION  Enterococcus faecium strain BMT-2-1-3 plasmid pSS-1-3_03, complete
            sequence.
ACCESSION   CP063650
VERSION     CP063650.1
DBLINK      BioProject: PRJNA669626
            BioSample: SAMN16483155
KEYWORDS    .
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15826)
  AUTHORS   Both,A., Kruse,F., Mirwald,N., Franke,G., Christner,M., Huang,J.,
            Hansen,J.L., Kroger,N., Berneking,L., Lellek,H., Aepfelbacher,M. and
            Rohde,H.
  TITLE     Population dynamics in colonizing vancomycin-resistant Enterococcus
            faecium isolated from immunosuppressed patients
  JOURNAL   J Glob Antimicrob Resist 28, 267-273 (2022)
   PUBMED   35134550
REFERENCE   2  (bases 1 to 15826)
  AUTHORS   Both,A., Kruse,F., Christner,M., Huang,J., Mirwald,N., Franke,G. and
            Rohde,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute of Medical Microbiology, Virology
            and Hygiene, University Medical Center Hamburg-Eppendorf,
            Martinistr. 52, Hamburg, Hamburg 20246, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Trycycler v. v0.3.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 663.5x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 10/28/2020 10:18:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.13
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,215
            CDSs (total)                      :: 3,123
            Genes (coding)                    :: 2,950
            CDSs (with protein)               :: 2,950
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 93 of 173
            Pseudo Genes (incomplete)         :: 76 of 173
            Pseudo Genes (internal stop)      :: 31 of 173
            Pseudo Genes (multiple problems)  :: 25 of 173
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..15826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="BMT-2-1-3"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pSS-1-3_03"
                     /geo_loc_name="Germany: Hamburg"
                     /lat_lon="53.33 N 10.1 E"
                     /collection_date="2014-07-08"
                     /collected_by="Institute of Medical Microbiology, Virology
                     and Hygiene, University Medical Center Hamburg-Eppendorf"
     gene            1..1041
                     /locus_tag="IQN07_15970"
     CDS             1..1041
                     /locus_tag="IQN07_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="UOC48506.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1658..2338)
                     /locus_tag="IQN07_15975"
     CDS             complement(1658..2338)
                     /locus_tag="IQN07_15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOC48507.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2413..2601
                     /locus_tag="IQN07_15980"
                     /pseudo=""
     CDS             2413..2601
                     /locus_tag="IQN07_15980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /name="topoisomerase C-terminal repeat-containing protein"
     gene            2735..2976
                     /locus_tag="IQN07_15985"
                     /pseudo=""
     CDS             2735..2976
                     /locus_tag="IQN07_15985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /name="peptide-binding protein"
     gene            3025..3108
                     /locus_tag="IQN07_15990"
     CDS             3025..3108
                     /locus_tag="IQN07_15990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="UOC48511.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYTDK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            3233..3970
                     /gene="erm(B)"
                     /locus_tag="IQN07_15995"
     ARG             3234..3967
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4140..4400
                     /locus_tag="IQN07_16000"
                     /pseudo=""
     CDS             4140..4400
                     /locus_tag="IQN07_16000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            complement(4557..5852)
                     /locus_tag="IQN07_16005"
     CDS             complement(4557..5852)
                     /locus_tag="IQN07_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="UOC48509.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFL
                     VTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
                     /name="ISL3-like element ISEfa11 family transposase"
     gene            6085..6384
                     /locus_tag="IQN07_16010"
                     /pseudo=""
     CDS             6085..6384
                     /locus_tag="IQN07_16010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(6435..7115)
                     /locus_tag="IQN07_16015"
     CDS             complement(6435..7115)
                     /locus_tag="IQN07_16015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOC48510.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            7142..7837
                     /locus_tag="IQN07_16020"
     CDS             7142..7837
                     /locus_tag="IQN07_16020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48512.1"
                     /translation="MILPYLIVDLKLCNRTEHLNEVIRRIQKDFSCMEEMKYFIQRVEE
                     QLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENF
                     VSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIV
                     LMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPY
                     QRFERKKRQ"
                     /name="hypothetical protein"
     gene            8218..8397
                     /locus_tag="IQN07_16025"
     CDS             8218..8397
                     /locus_tag="IQN07_16025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48496.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            8528..8797
                     /locus_tag="IQN07_16030"
     CDS             8528..8797
                     /locus_tag="IQN07_16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="UOC48497.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            8790..9047
                     /locus_tag="IQN07_16035"
     CDS             8790..9047
                     /locus_tag="IQN07_16035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="UOC48498.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            9506..10510
                     /locus_tag="IQN07_16040"
     CDS             9506..10510
                     /locus_tag="IQN07_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48499.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(10675..11289)
                     /locus_tag="IQN07_16045"
     CDS             complement(10675..11289)
                     /locus_tag="IQN07_16045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UOC48500.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            11739..13064
                     /locus_tag="IQN07_16050"
     CDS             11739..13064
                     /locus_tag="IQN07_16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UOC48501.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            13057..13407
                     /locus_tag="IQN07_16055"
     CDS             13057..13407
                     /locus_tag="IQN07_16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48513.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            13404..13583
                     /locus_tag="IQN07_16060"
     CDS             13404..13583
                     /locus_tag="IQN07_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48502.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            13719..14009
                     /locus_tag="IQN07_16065"
     CDS             13719..14009
                     /locus_tag="IQN07_16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="UOC48503.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="type III secretion system protein PrgN"
     gene            14362..15165
                     /locus_tag="IQN07_16070"
     CDS             14362..15165
                     /locus_tag="IQN07_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UOC48504.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDI
                     DPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFT
                     QVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLI
                     KLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRR
                     TITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="ParA family protein"
     gene            15152..15478
                     /locus_tag="IQN07_16075"
     CDS             15152..15478
                     /locus_tag="IQN07_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC48505.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             3234..3970
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcgtatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgccgtg cccttcagtg ttacggtatt acccgcaacg gacggttctg ttgcaaagtt
     1621 ttaaataaag aataaaatcc cttacggtat ctatgattta agctgggatt cccaataata
     1681 ccttgatttc agtacagacc gaaaacccga agagagtgcc ttcttttcgg gttttcttat
     1741 ataatcctcg aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat
     1801 agaatttatt gcgtctcttt actggacgat ggtcttgttc aatcaaatta ttcaggtatt
     1861 taatggtacg atgttctgtc ccttgataaa agccgtattc ttttagtttc ttaaaggcac
     1921 ttgtaataga gggggcttta tctgtgacta caaccttcgg ttcatcaaac tgcttcacta
     1981 accgcttaag aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac caaatatcca
     2041 aggttaaacc atctgcatcg atggctcgat acaaataatg ccattttcct ttaattttga
     2101 tgtacgtttc atccattttc catgaataaa aggatttttt atttttcttt ttccaaattt
     2161 gatagagtag tttgccatat tcttgcaccc aacgataaat cgtcgtatga gaaacgttaa
     2221 tgccacgatc atataagatt tcttgaactt cacgatagct aaggttataa cgaagatagt
     2281 agcccacggc tacaataatc acatcctgct gaaattgctt tcctttaaaa tgattcatcg
     2341 tcattcctcc tgctatcttt ttctattatt ctaccttatt tgatagtaga tttaaaactt
     2401 tgcaacagaa cccctgaatg taagtttact ttagctgaac attttagaaa gaaaaaacta
     2461 accaaaacga atgtaaaaga attactggag ggaaaagaaa ccctggtaaa aggaatcaaa
     2521 aacaaagaga aaaagcccta caatgccgtt gtaaaaattg gggaaaaggg atatattgat
     2581 tttatatctt tctcaaaata aacataaaag ccctttaaag agggctttta tatattaatc
     2641 acaaatcact tatcacaaat cacttatcac aaatcacaag tgatttgtga ttgttgatga
     2701 taaaataaga ataagaagaa atagaaagaa gtgagtgatt gtgggaaatt taggcgcaca
     2761 aaaagaaaaa cgaaatgata caccaatcag tgcaaaaaaa gatataatgg gagataagac
     2821 ggttcgtgtt cgtgctgact tgcaccatat cataaaaatc gaaacagcaa agaatggcgg
     2881 aaacgtaaaa gaagttatgg aaataagact tagaagcaaa cttaagagtg tgttgatagt
     2941 gcagtatctt aaaattttgt gtataatagg aattgaagtt aaattagatg ctaaaaattt
     3001 gtaattaaga aggagggatt cgtcatgttg gtattccaaa tgcgtaatgt agataaaaca
     3061 tctactgttt tgaaacagac taaaaacagt gattacacag ataaataaat acgttagatt
     3121 aattcctacc agtgactaat cttatgactt tttaaacaga taactaaaat tacaaacaaa
     3181 tcgtttaact tctgtattta tttacagatg taatcacttc aggagtgatt acatgaacaa
     3241 aaatataaaa tattctcaaa actttttaac gagtgaaaaa gtactcaacc aaataataaa
     3301 acaattgaat ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta aagggcattt
     3361 aacgacgaaa ctggctaaaa taagtaaaca ggtaacgtct attgaattag acagtcatct
     3421 attcaactta tcgtcagaaa aattaaaact gaacattcgt gtcactttaa ttcaccaaga
     3481 tattctacag tttcaattcc ctaacaaaca gaggtataaa attgttggga gtattcctta
     3541 ccatttaagc acacaaatta ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta
     3601 tctgattgtt gaagaaggat tctacaagcg taccttggat attcaccgaa cactagggtt
     3661 gctcttgcac actcaagtct cgattcagca attgcttaag ctgccagcgg aatgctttca
     3721 tcctaaacca aaagtaaaca gtgtcttaat aaaacttacc cgccatacca cagatgttcc
     3781 agataaatat tggaagctat atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg
     3841 tcaactgttt actaaaaatc agtttcatca agcaatgaaa cacgccaaag taaacaattt
     3901 aagtaccgtt acttatgagc aagtattgtc tatttttaat agttatctat tatttaacgg
     3961 gaggaaataa ttctatgagt cgctttttta aatttggaaa gttacacgtt actaaaggga
     4021 atggagataa attattagat atactactga cagcttccaa gaagctaaag aggtccctag
     4081 cgcctacggg gaatttgtat cgataagggg tacaaattcc cactaagcgc tcgggacccc
     4141 ttgtaggaaa atgtcctaag tgtggcaaca atattgtatt aaaaaaatcg ttttatggtt
     4201 gttcaaatta tcctgaatgt aagtttactt tagctgaaca ttttagaaag aaaaaactaa
     4261 ccaaaacgaa tgtaaaagaa ttactggagg gaaaagaaac cctggtaaaa ggaatcaaaa
     4321 acaaagagaa aaagccctac aatgccgttg taaaaattgg ggaaaaggga tatattgatt
     4381 ttatctcttt ttcaaaataa acatggggct gacccaaaag tagctcctat atgaaaaata
     4441 gaggtctttc catttagata gtagtggaaa gaccggctct ttgtcaataa ggactgatga
     4501 gttgtgcaaa atcaaatctg agtcagaatg aaccacattc tggctcagat tttttgttat
     4561 cttacattga ttaattgatt gatcaaaaag attctaattc tcatgttctc aaatgattta
     4621 aatccgtagg atactcgttt cattgtcttt atgtgggtat tcttcgcttc tatttttcca
     4681 ttggaataag gatagatcat tgcgttggtg atgccttctt cataggtcag aaggttttga
     4741 agcttttccc gaaagctgtc atctaacgtt tcgggaagtt ctgccaataa ggagaaaaat
     4801 aagtcagggt ctttgtctcg aaaggcttca actaattcat gaaaaaaggg atacgcctcc
     4861 tttaggggcg gagaaaactc aagcaatcga tcaatcatca ttgcttcagt aagaaatggg
     4921 tattttggtg ctcggaaact tttccatgtt ttgtattcat aatggttgat gtttgcacga
     4981 ttttttagca aaaagcgcca gttctttttc agtttttctg cctggctttt ctgtccggct
     5041 ttacgaagtt cattcatttc acggatacgc aactcattga acgcttgatt catgtgtttg
     5101 acaatatgaa accgatcaat cacgactttc gcatttggca gaacacgttt ggtgagctgg
     5161 aagtaggcgg cgttcatgtc tgtcaccaag aattctactt cttctggatt ggtacaacct
     5221 aagaaatagc ttgttaatcg aggtaattta cgcgtaggca aaacatctat taattttcct
     5281 gtttcgccat ccgcgcaaat aaagctcatc ttatcttcta tggaagcatg cgaacgaaat
     5341 tcgtcaacca tcaatactct ggggaggatc ttcttagatt gctttggtaa atagctttta
     5401 aactctttca atgtacgaat aacggtggtc aaagatacct gacagctttt cgcaataaaa
     5461 gataaagata ctttttcagt cagtaaagaa gcaattttat atctaacatg atttgcgatt
     5521 gaatgtctgg gttggacaaa ataactttga gccgtccaat gggtgcgaca gtttttacag
     5581 gtatagcgtt gcttttttag gcgcataacc aaaggcatat gattgtattg ttcaaaacgg
     5641 acaatcgttt ccttttttcc atttttcact ataattgctt tcccgtttcc atctaccaca
     5701 gtagaaccac aacttctaca agcacgagga gtaggcgaga gaacagcatc gacgaccaac
     5761 gtctttttct tctgaagggt ctcgtaagag acctctgtaa tcatcaaatc tttctctgtt
     5821 attctcagca tttttttgat agaatcattc atatagcgta tcgtcctctc agttgtttat
     5881 tttgtggtga tttaatcata ctagagaacg atatgttttt taatacctaa aatgaaaatg
     5941 gggctgaaga atcaattctg attcatcagt cccataaatt atagagccga aagacctcta
     6001 tttatctttt gaaagtgaat acaaaaataa agcacactct gctataatat aggtgattaa
     6061 tccatttgag agaggtgctt tatcatgtat caaaattata ccataaacca actttgtttg
     6121 cctatagatc ttgaaattaa attagaagaa aatgattttg ctcatgccat tgtgcagttt
     6181 gttgactcta ttcccgatga agtctttctt ccttattatc aatctatggg tagaccccaa
     6241 tatcatcctc gtatgctact ttccattatt ctttgtgcct atattcaagg ggtttattcg
     6301 ggccgccaaa tacaaaatat gctgatagat agtattcgga tgcgctactt atctcaagag
     6361 caattcccta actttcgtac ggttctgttg caaagtttta aataaagaat aaaatccctt
     6421 acggtatcta tgatttaagc tgggattccc aataatacct tgatttcagt acagaccgaa
     6481 aacccgaaga gagtgccttc ttttcgggtt ttcttatata atcctcgaat ggcttccatg
     6541 cctttaatcg tggtagaggc agtgcgtaaa cttcgataga atttattgcg tctctttact
     6601 ggacgatggt cttgttcaat caaattattc aggtatttaa tggtacgatg ttctgtccct
     6661 tgataaaagc cgtattcttt tagtttctta aaggcacttg taatagaggg ggctttatct
     6721 gtgactacaa ccttcggttc atcaaactgc ttcactaacc gcttaagaaa agcataggct
     6781 gcttgtgtgt cccgtttttt acgtaaccaa atatccaagg ttaaaccatc tgcatcgatg
     6841 gctcgataca aataatgcca ttttccttta attttgatgt acgtttcatc cattttccat
     6901 gaataaaagg attttttatt tttctttttc caaatttgat agagtagttt gccatattct
     6961 tgcacccaac gataaatcgt cgtatgagaa acgttaatgc cacgatcata taagatttct
     7021 tgaacttcac gatagctaag gttataacga agatagtagc ccacggctac aataatcaca
     7081 tcctgctgaa attgctttcc tttaaaatga ttcatcgtca ttcctcctgc tatctttttc
     7141 tattattcta ccttatttga tagtagattt aaaactttgc aacagaaccg aacatttgaa
     7201 tgaagtaatc agacggattc aaaaagactt tagttgtatg gaagaaatga agtactttat
     7261 tcaaagagtc gaagaacaat tgtatttgga aagtgaaacg agtcaaacga aggtcacagt
     7321 cagccataat cgtttagacg tgtataaacg tcgtcctgaa acggtaaaaa aaggaacgga
     7381 gcttctacga ctagaaacag aaaaatacat catgaatgtt tacctagaaa ggagtgagct
     7441 ggtcgaaaac tttgtcagct acacgatttg caggaaacac tattactcag aatcagaata
     7501 ttattcaatt tttgagagca tggaattaat ggaagaagaa atggaagagc taaacagcaa
     7561 agatgcgacg atagacgatt attaccttgt atttactaga tttttgacgt gtggaacgga
     7621 atctatcgtg ttaatgggaa tggattatga actcgctgta cccgaagcat ttttgaggga
     7681 atatgtagaa gaagtagata acccaggcga cgactggtac acgactttaa ctgatttttt
     7741 agacacctat acttacgacg atacagaaga aatccaaaat gaacttgacc gtaaacgaat
     7801 gccatatcaa cgatttgaaa ggaaaaaaag gcaataatca tttataccga aaagtgagaa
     7861 tgtgtgaaat aaggacaaaa aacctagtaa ctaagggaat ggttcttatt tcgcaccaat
     7921 cgctccaacc gcccccgccg cttaggtggt gcgaaataag cgggcaacac ccgataacct
     7981 aagagaaaga aggagatcca tatgaataaa atcattcctc tattgttagt cctatttgtt
     8041 ggcgaaatac ttatgcgcca tgctgcagct gtgcatttaa acttcgtagt atttttggca
     8101 atactggtat tttgtttgat cttttggcgc tttgtattag cccttgtgag tctactattc
     8161 aagatgattg cagccatatt tttcataggg ttatttcgat gaaaggagag agtactaatg
     8221 ccaattgcaa taggaaataa acggttaccc gttacgttgg atgaaaagag acaaaaagaa
     8281 ttgcagcaac taaagcagaa gtacggcaaa agtgaatcca ggattatgtg tattgcgtta
     8341 gatttattga ttgcccaaga aaaagcagga tttgaggtac cagcactcaa aaagtgacgt
     8401 cactttttat cctaaaaact aaaagtgata gcacttttaa ttataagaag ttagaatatt
     8461 aatcatttgc ttaattgtac aatataatgt acaattgttt tatagaaata aataaggggt
     8521 gaaaggaatg gaagcagtag cttattcaaa tttccgccaa aatttacgta gttatatgaa
     8581 acaagttaat gaggatgctg aaacacttat tgtaacaagt aaagatgtag aagatacagt
     8641 tgttgtatta tcaaaaagag attatgattc tatgcaagaa acgttgagaa cactttctaa
     8701 taattacgtc atggaaaaaa ttcgtcgagg agatgaacaa ttctccaaag gtgcatttaa
     8761 aacacatgac ttaatcgagg ttgaatctga tgattaaggc ttggtctgat gatgcttggg
     8821 atgattatct ttattggcat gagcaaggaa acaaaagcaa tataaaaaag attaacaagt
     8881 taataaaaga tatcgatcgt tccccctttg ctggattagg aaaacctgag ccattaaagc
     8941 atgatttatc tggaaaatgg tccagaagaa ttacagatga acatagactg atatatagag
     9001 ttgaaaatga aacgatattt atttattctg caaaagatca ctattaacca atcggaagta
     9061 aggaaagggt cagaaactta aaagtttttg atccttattt tatttaccct agtcatttaa
     9121 aaagctaata tagcttagtg ttgattgtta ttaatgaatg tgtttgttac gcgtattacg
     9181 gatataaggt tagtaaaatc atttctaaag ttgaggaaaa gtaaatataa atggcttaaa
     9241 tttcaacaat ttgaagttga atagatatgt tataatacta ttgtagtgtg ggatgttagt
     9301 tactaaagga tgacgcttat atatatgact gaatagaata agcaataggt ttaataatct
     9361 attttaaatt ttttgtacta gttttagtta attagcaaaa acaacaaaaa taaacttctc
     9421 atagaattta gctaaaaatt aatgatttat ttacatatta aatttggata cagttaagta
     9481 atttttatat attggaggag aagtaatgga atataaattt aacttgaatt tgaaagaagt
     9541 actccccact cagggaacaa taaacataaa tggtcaagat aatgatgacg atatagtaat
     9601 aaaaaaaata gaatttattg attctgatat aaatgttttt ttttattcta aagaaaaatt
     9661 agctgatttt agcaatattg ctgaaatgat tgaacgttta aaagatttta tgatcagtgt
     9721 ttgggatgta gcgatgcttg ctgacgaatc aaattatact tcgagcatat acagattaga
     9781 agatagtaat tggatagaaa tttcattaga gttaaagaca cttcctaatt ccgttaacta
     9841 tataattaga gatataactt ctgaagctca acaattagtt aattacatgc atggacacga
     9901 aagtatcccc ttttctctta tactccttaa aagaagtaaa aatatatcaa atactagaga
     9961 taggtttatt tcgataatta cagcctgtga aataggggta aaggaatttt atcaacaaga
    10021 gaaacctgat ttaactctaa tatttgagaa tttacaatct ccccctgtag acaaattatt
    10081 agggagcatg tttaaagggt actttaatat tgagtttccg aaagaaataa gaaaggaaat
    10141 taaaaatttc atagaaaaac gtaataaatt ggttcattct cctcaaggaa gtaaaccaac
    10201 tatagaagaa tgttttgaat gttatatggc agtgctaaaa acatttaatt ttttttataa
    10261 aattaatgat agctttatgt atagagattt ttatgaagaa tctatagaat tgactccaac
    10321 ggaaccaaat aaatctcaaa tcactttgtc aaaggagcta gagagaaaag tagagtctca
    10381 agaactagct ataggaatta gtataaccaa tgtgtcgaca tacaaagaat tatacgaagc
    10441 taaatcacaa gataataagg attttgtaga aaatatagat aaggaaccaa caaatacagt
    10501 aggggattaa cgtaaataag tgaagattat attaacagac tctttattta gttaagtaaa
    10561 aaatggtttg ttggaatttt atgctttatc tgttctgagt aagacttaat tttatagata
    10621 gtaattatat gtaggaaatt aaagatgaga agataataaa agcagcatga tcaactattt
    10681 gtcattgacc atgctgtctt tttttattct atacacggtt tgtctcgtaa cattgtagtc
    10741 tttagcaatc ttagcaatcg caacaccatt tttaagatct tcaacgatgc ttttgtaaac
    10801 aaggcgacgt tggggatctt ttgcgtctgc actgtataat ttgggccgcc ctttgtagac
    10861 gccgtttgct tttgcgatct taattccttg tgcctggcga cgtttcgatt cagtccgttc
    10921 ttgttcagcg atcatggcca aaatttggat gatcagatcc ttaatgaatt tatccaggag
    10981 aggattgcca attgcttcag ccatgatcgg taaactagta atgatcagct tcacattttt
    11041 cttcttcaag taattgactg aagcgatgat ctcgtcataa tttcttccaa gtcgatcaat
    11101 agcttccaca ataaaaatat cttgatctcg gacgtaatct aatgcttctt ggaaaacagg
    11161 tcgatgagta atcgttgcgc cagattgttt ctcgatgaaa attctctctg caccgaattt
    11221 tttcatttct tcaatctggc gttgttcatt ttgatcgatc gatgagacac gtatgtatgc
    11281 aactctcaaa acttttacct actttctgca actatttaaa atacacccta atcatacacg
    11341 aggaagccat atttttcaat gttataccag tgtctattta gggtaaacct tatatagaca
    11401 aaaactaatg atggaggaaa tagtatgaga attttttgta agtgtctact gataacttat
    11461 tctcaaatgt tgtaaggatt ttattcattt gttaatatta aagaacggaa ctccaaaaaa
    11521 gtccgtactc taatttgcag tctctcactc ttttagagtg agagttttta ttagattttc
    11581 aaattaatta gtaaagtgat agaataaatt gatcatacaa atcaaaagaa gaagcagggt
    11641 gatagcatac ctatgcttct ttttttatgt atttagctat ttcttcttta caatatcgaa
    11701 catatgtttg tataatgtga aagaatggag tgttatttat gatggattat tcaaaagagc
    11761 cagtaaatga ttacttttta atcgatatga aaagctttta cgcaagtgtc gaatgtatag
    11821 aaagaaattt agatccatta acaacagaac ttgttgttat gagtcgagct gataatactg
    11881 gttcaggatt gatattagct tcttctcctg aagcaaaaaa gcggtatggt attacaaatg
    11941 tgagtagacc acgtgactta ccacaaccat ttcctaaaac actacacgtt gttccaccac
    12001 gtatgaacct atatatcaag cgaaatatgc aggtaaataa tattttcaga agatatgtgg
    12061 ctgatgaaga tctactgatt tactcgatcg atgaatcaat cttaaaagtg acccgatcac
    12121 tgaatctttt tacgactgaa ggaacacgaa gtcaacggag aaagaagctg gctcaaatga
    12181 tccaggagaa tattaaagaa gagctaggat tgattgctac agtaggtgtc ggagataatc
    12241 cccttttggc taaactagcc ttagacaacg aagcaaagca taatgaagga tttgttgcgg
    12301 aatggacgta cgaaaacgtt cctgaaaaag tatggaatat tcctgaaatg acggactttt
    12361 ggggaattgg ctctcgaatg aaaaaaagac tcaatcagat ggggattatg agcattagag
    12421 atcttgctaa ctggaatcct tatacgatta agaatagact aggtgtgatt ggcttacagc
    12481 tgtacttcca tgctaatggg atcgatcgaa cagatatagc aatcccacca gaaccgacaa
    12541 aggaaaaatc atatggaaat tcacaagtgt taccacgaga ttatactaga agaaatgaaa
    12601 tcgagctggt ggtaaaagaa atggcggaac aagtagcgat acgcattagg cagcataact
    12661 gtaaaacagg ttgtgtccat ttacacattg gcacgtcgat cttagaaacg agaccagggt
    12721 tttcacacca gatgaagatc cctatcacag ataatacaaa ggaattgcag aattattgtc
    12781 ttttcttgtt tgataagtat tatgaaggac aagaagtaag gcatgttgga ataacctata
    12841 gcaagcttgt gtacaccgat tcgcttcagc tggatttatt tagtgatcca caaaagcaaa
    12901 ttgacgaaga aaatttagat aaaattattg acaagattcg gcaaaaatat ggttttacgt
    12961 cgattgtaca tgcttcttca atgttagaag gcgctagaag cattactaga agcacacttg
    13021 ttggtggtca tgcgggcgga aatgggggaa ttaaaaatga ttgattacaa tgatcgtgga
    13081 cgtttaaagt gggcagggtt ttatttatct gatcatactg aagaaattga tgccgacaat
    13141 gaacaacgaa ccagtcaaaa tttagcaaaa gaacaaatga cgactgaaga gattgcggaa
    13201 gtattgaacg ctgcagtcat aaaaaataga tcagtatcta ttcaaaaaga agaacgaaac
    13261 gctgaaggat actatccaga agatatcatt ggcaagatct taggtagtga tgagctgggg
    13321 atctacgttg gaaaagacaa aattcactac gacgaaatac gtcatatcga attttaccag
    13381 gataataaat ggagtcgatt agaatgaaca ttatccagca atatgagcta aagtatataa
    13441 cctttgatca gctatcagaa gagatttggg gttatggcca acgtttgata aatgaggttg
    13501 gtgttgagcg cttctctttc tatgtagaag ctgcagcagg ttatcataat tttaggtttt
    13561 atatcttccc gttatatata taaggtattt tacggattct atagagttat ctctatgaat
    13621 ccttttttgt ttttacaaat aggagtagat actagaataa tgcgtgtgtt aaactattat
    13681 tgcaaacgca ataataaaag aaagtaggct tacgcaccat gtctatcaat acatttgttt
    13741 actcgcaccc gatcaatgtt tacattatca agaatttagg aatcactgta gaacaatttt
    13801 gtgagttata tgcctaccca caaggaacgg ttgcaagctg gataacccga caacgtagaa
    13861 taaaatcatt acctgcttca ttcgtttatg atttaagcct ggcctctagt ttaaacatgt
    13921 ctgatgttta tgaaaagctc ctgtctttag aaaaagaata tgattccttc aagattaaac
    13981 atgataaaaa aataaaaaaa catatataat atcaatcaca attgtataat attacgatat
    14041 cttaatatca tgatatcgta atattgtttt tttctaagaa aatgcactat aagaagggaa
    14101 ttattagtaa caatatagac agtttagtaa tgtttaaatt attctagttg ctgctcgcaa
    14161 aacatatttc ttatcattaa taaaaaattt taaagtaata aaaagtgatt attttaattt
    14221 cgaataacat atgaataatc tttatatccg aaccgatata tatctttaaa acaaaataat
    14281 cacacaatat tacaatataa tgcatatacg atattgcaat atcacaatat tatgatataa
    14341 ttatattata atataagatg aatgggggat attttaatgg caagaatatt gtcagtagcc
    14401 aatcaaaaag gtggagtttc taaaactacg actagcgtta atttagcagc atgtttgaaa
    14461 tttgtttacg gtaaaaatgt acttttagtg gacattgatc ctcagggaaa tgctacagat
    14521 aatgtaggtt tcgatataga tggaacaaac caacctacaa tttatgaagt attaaaaggg
    14581 gaggctgaca ttacagatgc tattctggac tataaaggaa ttgatgtttt gccagccgac
    14641 atagcccttt cttctgcaga gagggaattt actcaagtag gaagtgaaca caggcttaaa
    14701 agagtacttc aaccaatcaa ggacaactat gattatatta taattgattg tccaccaagt
    14761 ttaggaatgc ttacagtcaa cgcatttact gtttctgatg aaattatcat tccagttgaa
    14821 gctgcgtatt tctcattaaa aggactaata aagttaagtg aaactattga aacggtaaaa
    14881 gaatatacga acgacaagct tgaagtacga ggagttctat ttactaagta taataagcgt
    14941 tataacattt ctaaagaaat gacgtctgca gcaaccgaaa tttctagagt cattggtgca
    15001 aaaattttca aaacttatat tcgtaggaca ataaccgttg acgaagcgca agctgctgga
    15061 tcagatctaa tcaattttaa taaaccctca acagctgaag atgactataa agcatttaca
    15121 gaagaatatt taaaagaagt tggtgatttt gatggcagaa gataatcgca gtcaagctgc
    15181 agtaagtaga ttactaggaa ataaaaataa aaagaatttt aaatcaaaag aagtagaaga
    15241 aatcgaatta accaagaaaa atataagtaa agtcataaaa gatcaaggaa gtagtgtaag
    15301 aacagcagat agcattcgta taaatccaat tctaatgtca gcactcaaat attggacgac
    15361 tattgctgaa tcagacaaaa gtaaaccaga cgttatagaa gatgcgctat taaagtccat
    15421 acctgaagaa tacttgattg aaggatataa actagcaaag aaacaaaata aaatttaatt
    15481 tacattcaat atcacgatat cataatatcg tgatattttt tttataaaaa tcagtagtat
    15541 caaagctgat aagtcgctta tcttcatatt gtaatattac gatatcgtga tataatatta
    15601 ttgtaatatc gtgatatagt tactatgagc ttaaaccttg aaatagagcg gtttgcttta
    15661 atttattttt taaggtaaac taaaaaaaga taaaaaaaga ctactgcttt aacaaagttt
    15721 ggcgacttat cagcagtaga aaaatatata gtggatagat atatttgttt aattcattgt
    15781 aacatagttt tgaacaaaac gctatcctac agaaagagga ttggct
//
