LOCUS       CP063614               16138 bp    DNA     circular BCT 04-APR-2022
DEFINITION  Enterococcus faecium strain ICU-1-1 plasmid pZA1-1_03, complete
            sequence.
ACCESSION   CP063614
VERSION     CP063614.1
DBLINK      BioProject: PRJNA669626
            BioSample: SAMN16483154
KEYWORDS    .
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16138)
  AUTHORS   Both,A., Kruse,F., Mirwald,N., Franke,G., Christner,M., Huang,J.,
            Hansen,J.L., Kroger,N., Berneking,L., Lellek,H., Aepfelbacher,M. and
            Rohde,H.
  TITLE     Population dynamics in colonizing vancomycin-resistant Enterococcus
            faecium isolated from immunosuppressed patients
  JOURNAL   J Glob Antimicrob Resist 28, 267-273 (2022)
   PUBMED   35134550
REFERENCE   2  (bases 1 to 16138)
  AUTHORS   Both,A., Kruse,F., Christner,M., Huang,J., Mirwald,N., Franke,G. and
            Rohde,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute of Medical Microbiology, Virology
            and Hygiene, University Medical Center Hamburg-Eppendorf,
            Martinistr. 52, Hamburg, Hamburg 20246, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.9x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 10/27/2020 18:01:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.13
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,192
            CDSs (total)                      :: 3,099
            Genes (coding)                    :: 3,002
            CDSs (with protein)               :: 3,002
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 29 of 97
            Pseudo Genes (incomplete)         :: 58 of 97
            Pseudo Genes (internal stop)      :: 20 of 97
            Pseudo Genes (multiple problems)  :: 9 of 97
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..16138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="ICU-1-1"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pZA1-1_03"
                     /geo_loc_name="Germany: Hamburg"
                     /lat_lon="53.33 N 10.1 E"
                     /collection_date="2019-03-01"
                     /collected_by="Institute of Medical Microbiology, Virology
                     and Hygiene, University Medical Center Hamburg-Eppendorf"
     gene            1..1041
                     /locus_tag="IQN06_15775"
     CDS             1..1041
                     /locus_tag="IQN06_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="UOC51488.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1656..2336)
                     /locus_tag="IQN06_15780"
     CDS             complement(1656..2336)
                     /locus_tag="IQN06_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOC51489.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPD"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(2707..3123)
                     /locus_tag="IQN06_15785"
     CDS             complement(2707..3123)
                     /locus_tag="IQN06_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51490.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSYE
                     PDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKIEA
                     KLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(3126..3410)
                     /locus_tag="IQN06_15790"
     CDS             complement(3126..3410)
                     /locus_tag="IQN06_15790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51491.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESDF
                     DRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
                     /name="hypothetical protein"
     gene            3755..4000
                     /locus_tag="IQN06_15795"
     CDS             3755..4000
                     /locus_tag="IQN06_15795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51492.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMT
                     PERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
                     /name="hypothetical protein"
     gene            complement(4302..4397)
                     /locus_tag="IQN06_15800"
     CDS             complement(4302..4397)
                     /locus_tag="IQN06_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="UOC51493.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5145..5825)
                     /locus_tag="IQN06_15805"
     CDS             complement(5145..5825)
                     /locus_tag="IQN06_15805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOC51494.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            5901..6467
                     /locus_tag="IQN06_15810"
                     /pseudo=""
     CDS             5901..6467
                     /locus_tag="IQN06_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6848..7027
                     /locus_tag="IQN06_15815"
     CDS             6848..7027
                     /locus_tag="IQN06_15815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51495.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            7158..7427
                     /locus_tag="IQN06_15820"
     CDS             7158..7427
                     /locus_tag="IQN06_15820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="UOC51496.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            7420..7677
                     /locus_tag="IQN06_15825"
     CDS             7420..7677
                     /locus_tag="IQN06_15825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="UOC51497.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            8315..8902
                     /locus_tag="IQN06_15830"
                     /pseudo=""
     CDS             8315..8902
                     /locus_tag="IQN06_15830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            9057..10376
                     /locus_tag="IQN06_15835"
     CDS             9057..10376
                     /locus_tag="IQN06_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="UOC51481.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSEL
                     AKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKELAS
                     QSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQTNY
                     NTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPNTDIL
                     VRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREVQYFST
                     TYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGTMENFIK
                     EAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHSIRLKFLK
                     VAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
                     /name="IS1380-like element IS1678 family transposase"
     gene            10580..10822
                     /locus_tag="IQN06_15840"
                     /pseudo=""
     CDS             10580..10822
                     /locus_tag="IQN06_15840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(10987..11601)
                     /locus_tag="IQN06_15845"
     CDS             complement(10987..11601)
                     /locus_tag="IQN06_15845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UOC51482.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            12051..13376
                     /locus_tag="IQN06_15850"
     CDS             12051..13376
                     /locus_tag="IQN06_15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UOC51483.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            13369..13719
                     /locus_tag="IQN06_15855"
     CDS             13369..13719
                     /locus_tag="IQN06_15855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51484.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            13716..13895
                     /locus_tag="IQN06_15860"
     CDS             13716..13895
                     /locus_tag="IQN06_15860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51485.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            14031..14321
                     /locus_tag="IQN06_15865"
     CDS             14031..14321
                     /locus_tag="IQN06_15865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="UOC51486.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="type III secretion system protein PrgN"
     gene            14674..15477
                     /locus_tag="IQN06_15870"
     CDS             14674..15477
                     /locus_tag="IQN06_15870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UOC51487.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDI
                     DPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFT
                     QVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLI
                     KLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRR
                     TITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="ParA family protein"
     gene            15464..15790
                     /locus_tag="IQN06_15875"
     CDS             15464..15790
                     /locus_tag="IQN06_15875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOC51498.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcgcaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaagaaag gcccctgtaa
     1501 ggctcgggag actggtaatc tccgtcagtg tcctacagga aagcattaag atgacgcctt
     1561 aatgcgtgcc cttcagtgtt acggtattac ccgcaacgga cggttctgtt gcaaagtttt
     1621 aaataaagaa taaaatccct tacggtatct atgatttaat ctgggattcc caataatacc
     1681 ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt tttcttatat
     1741 aatcctcgga tggcttccat gcctttaatc gtgggtgagg cagtgcgtaa acttcgatag
     1801 aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt caggtattta
     1861 atggtacgat gttctgtccc ttgataaaat ccgtattctt ttagtttctt aaaggcacta
     1921 gcaattgatg gtgctttatc tgtgactaca accttcggtt catcaaactg cttcactaac
     1981 cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca aatatccaag
     2041 gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt aattttgatg
     2101 tacgtttcat ccattttcca ggaataaaag gattttttat ttttcttttt ccaaatttga
     2161 tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg
     2221 ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg aagatagtag
     2281 cccacggcta caataatcac atcctgctga aattgctttc ctttaaaatg attcatcgtc
     2341 attcctcctg ctatcttttt ctattattct accttatttg atagtagatt taaaactttg
     2401 caacagaacc aaatcctgca ttacgagaac taaaaaaata cttcaatgat cttaaagtca
     2461 caaaaataaa agcaaaaaag ggcaataaaa tcgccaaatt agaatttact ttttcaagcc
     2521 taacgtcaga tttgccaaag atttctctgc gtaactggtt agaagaataa ataaaaaaga
     2581 actcgccccc cttacattaa gcaagtagac aagtccctta caaccgacta agattgctag
     2641 tacattctag catattgtat ggggcttcta aataaaaaac agataggaat aactcctatc
     2701 tgttttttat cgttttagaa aatttgttgg gtcgaaattt ctagaagtga ctgtttgact
     2761 ggtttctttt tgatgattct ttggtcgatt tcgatttgat ggatttagtt tagcttcgat
     2821 tttttctttc acttcttgat atactttaga atttgtgcca ataagaacgc ctgtatcttt
     2881 tagatataaa tcagcaaatt ctgcgatgat ttcagtcatg atggaaattt cttttcccat
     2941 agcatttagt tttgcctgat tgctggtagt ggtcgtgttg gtatcgggtt cataactcat
     3001 acataaaaag cgaatggctt ccgagtagtt attgatatct ggattttttt cgatgatgga
     3061 atctaaaacg tcaacatgac tagggtacaa agtaacatgt ttttggacag aagtttttct
     3121 catggttata tcattcctcc gataagcatt tcaatgattt gattatttgt gtagacatac
     3181 tcgcttaata tttgagtatt ttctgtttgg atagcaataa atttatcgag caataaatcg
     3241 aattggtctt ttttgtaagt cgtaagttga cggtcaaaat cactttcgat taaaactttt
     3301 agatatttat ttcgactcca tttttctcct gttttattcg tgagttcttg gcaacgtttg
     3361 tctattgttg caacaaactt tggatcaata ttccgaacta aaatgtccat aaaaaatctc
     3421 cttttgcaat tatgtataat ttatgtatac catacaaata ctatatttgt atagctgttt
     3481 tttgccaaaa tgctatacat aagctaccca cgatggcgaa aaagtgatat caaatttttt
     3541 tctgagaaac gtgataggca cagcctatct acccactttt tttagaaagt gggtacacgt
     3601 ttccttatgc tctttaaaat tcggggggga gtgctgcacg tgtaatcgat aaccaaattt
     3661 aaaaatgcac gatcaaaaat ttatttagtt tttcaaacga catttttttt gagagtatag
     3721 acggcaaaga agtgatttta tttctagaaa aattgtgaga ctggagaaag aaaaaatgga
     3781 aaaatttcct tacgaatatt ttcaaaactt agaaaaatta gagcaagcaa ttcaagcaat
     3841 caagttcgat ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa
     3901 acgatcgttg gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc
     3961 ttttgacgca tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa
     4021 aatcgcttct aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac
     4081 gtcttaaatc gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag
     4141 aaataattac ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt
     4201 ataatttgat tgcaaataag tgaacacgaa acacacgaaa gccccagaga ggtcggattc
     4261 tctggggctt tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta
     4321 ttcaaccagt aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta
     4381 gtgaacacga aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta
     4441 tacaataaaa aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg
     4501 ccctgaccgc ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt
     4561 agaacggctt agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg
     4621 cgaaggagcc taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc
     4681 ttacagcgac catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt
     4741 taaaaagtgg gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt
     4801 attttttaaa gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg
     4861 gatacagaag ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact
     4921 aacaactttt tatctgagta ctaacaactt tttatctgag tactaacaac tttttatctg
     4981 agtactaata tccttttgta taataacaac caacctattt acgagttggt tgttaaaggt
     5041 tattatttat ttgtaagggg ggaagaaagg aatggatgaa aaaacggaat ggttctgttg
     5101 caaagtttta aataaagaat aaaatccctt acggtatcta tgatttaagc tgggattccc
     5161 aataatacct tgatttcagt acagaccgaa aacccgaaga gagtgccttc ttttcgggtt
     5221 ttcttatata atcctcgaat ggcttccatg cctttaatcg tggtagaggc agtgcgtaaa
     5281 cttcgataga atttattgcg tctctttact ggacgatggt cttgttcaat caaattattc
     5341 aggtatttaa tggtacgatg ttctgtccct tgataaaagc cgtattcttt tagtttctta
     5401 aaggcacttg taatagaggg ggctttatct gtgactacaa ccttcggttc atcaaactgc
     5461 ttcactaacc gcttaagaaa agcataggct gcttgtgtgt cccgtttttt acgtaaccaa
     5521 atatccaagg ttaaaccatc tgcatcgatg gctcgataca aataatgcca ttttccttta
     5581 attttgatgt acgtttcatc cattttccat gaataaaagg attttttatt tttctttttc
     5641 caaatttgat agagtagttt gccatattct tgcacccaac gataaatcgt cgtatgagaa
     5701 acgttaatgc cacgatcata taagatttct tgaacttcac gatagctaag gttataacga
     5761 agatagtagc ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga
     5821 ttcatcgtca ttcctcctgc tatctttttc tattattcta ccttatttga tagtagattt
     5881 aaaactttgc aacagaaccc gaagaacaat tgtatttgga aagtgaaacg agtcaaacga
     5941 aggtcacagt cagccataat cgtttagacg tgtataaacg tcgtcctgaa acggtaaaaa
     6001 aaggaacgga gcttctacga ctagaaacag aaaaatacat catgaatgtt tacctagaaa
     6061 ggagtgagct ggtcgaaaac tttgtcagct acacgatttg caggaaacac tattactcag
     6121 aatcagaata ttattcaatt tttgagagca tggaattaat ggaagaagaa atggaagagc
     6181 taaacagcaa agatgcgacg atagacgatt attaccttgt atttactaga tttttgacgt
     6241 gtggaacgga atctatcgtg ttaatgggaa tggattatga actcgctgta cccgaagcat
     6301 ttttgaggga atatgtagaa gaagtagata acccaggcga cgactggtac acgactttaa
     6361 ctgatttttt agacacctat acttacgacg atacagaaga aatccaaaat gaacttgacc
     6421 gtaaacgaat gccatatcaa cgatttgaaa ggaaaaaaag gcaataatca tttataccga
     6481 aaagtgagaa tgtgtgaaat aaggacaaaa aacctagtaa ctaagggaat ggttcttatt
     6541 tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag cgggcaacac
     6601 ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc tattgttagt
     6661 cctatttgtt ggcgaaatac ttatgcgcca tgctgcagct gtgcatttaa acttcgtagt
     6721 atttttggca atactggtat tttgtttgat cttttggcgc tttgtattag cccttgtgag
     6781 tctactattc aagatgattg cagccatatt tttcataggg ttatttcgat gaaaggagag
     6841 agtactaatg ccaattgcaa taggaaataa acggttaccc gttacgttgg atgaaaagag
     6901 acaaaaagaa ttgcagcaac taaagcagaa gtacggcaaa agtgaatcca ggattatgtg
     6961 tattgcgtta gatttattga ttgcccaaga aaaagcagga tttgaggtac cagcactcaa
     7021 aaagtgacgt cactttttat cctaaaaact aaaagtgata gcacttttaa ttataagaag
     7081 ttagaatatt aatcatttgc ttaattgtac aatataatgt acaattgttt tatagaaata
     7141 aataaggggt gaaaggaatg gaagcagtag cttattcaaa tttccgccaa aatttacgta
     7201 gttatatgaa acaagttaat gaggatgctg aaacacttat tgtaacaagt aaagatgtag
     7261 aagatacagt tgttgtatta tcaaaaagag attatgattc tatgcaagaa acgttgagaa
     7321 cactttctaa taattacgtc atggaaaaaa ttcgtcgagg agatgaacaa ttctccaaag
     7381 gtgcatttaa aacacatgac ttaatcgagg ttgaatctga tgattaaggc ttggtctgat
     7441 gatgcttggg atgattatct ttattggcat gagcaaggaa acaaaagcaa tataaaaaag
     7501 attaacaagt taataaaaga tatcgatcgt tccccctttg ctggattagg aaaacctgag
     7561 ccattaaagc atgatttatc tggaaaatgg tccagaagaa ttacagatga acatagactg
     7621 atatatagag ttgaaaatga aacgatattt atttattctg caaaagatca ctattaacca
     7681 atcggaagta aggaaagggt cagaaactta aaagtttttg atccttattt tatttaccct
     7741 agtcatttaa aaagctaata tagcttagtg ttgattgtta ttaatgaatg tgtttgttac
     7801 gcgtattacg gatataaggt tagtaaaatc atttctaaag ttgaggaaaa gtaaatataa
     7861 atggcttaaa tttcaacaat ttgaagttga atagatatgt tataatacta ttgtagtgtg
     7921 ggatgttagt tactaaagga tgacgcttat atatatgact gaatagaata agcaataggt
     7981 ttaataatct attttaaatt ttttgtacta gttttagtta attagcaaaa acaacaaaaa
     8041 taaacttctc atagaattta gctaaaaatt aatgatttat ttacatatta aatttggata
     8101 cagttaagta atttttatat attggaggag aagtaatgga atataaattt aacttgaatt
     8161 tgaaagaagt actccccact cagggaacaa taaacataaa tggtcaagat aatgatgacg
     8221 atatagtaat aaaaaaatag aatttattga ttctgatata aatgtttttt tttattctaa
     8281 agaaaaatta gctgatttta gcaatattgc tgaaatgatt gaacgtttaa aagattttat
     8341 gatcagtgtt tgggatgtag cgatgcttgc tgacgaatca aattatactt cgagcatata
     8401 cagattagaa gatagtaatt ggatagaaat ttcattagag ttaaagacac ttcctaattc
     8461 cgttaactat ataattagag atataacttc tgaagctcaa caattagtta attacatgca
     8521 tggacacgaa agtatcccct tttctcttat actccttaaa agaagtaaaa atatatcaaa
     8581 tactagagat aggtttattt cgataattac agcctgtgaa ataggggtaa aggaatttta
     8641 tcaacaagag aaacctgatt taactctaat atttgagaat ttacaatctc cccctgtaga
     8701 caaattatta gggagcatgt ttaaagggta ctttaatatt gagtttccga aagaaataag
     8761 aaaggaaatt aaaaatttca tagaaaaacg taataaattg gttcattctc ctcaaggaag
     8821 taaaccaact atagaagaat gttttgaatg ttatatggca gtgctaaaaa catttaattt
     8881 tttttataaa attaatgata gcctgaataa ttcatacttt taattaaaac catgtgaaac
     8941 tgcctcacgg cagcttacaa ttactttttc atcttcaccc gttaagtgat gaaaaaagaa
     9001 cccctttctg ctatggttaa agtgactaaa ccaaccaaaa gaaaggagtt cttttcatga
     9061 ctagcttaca caaaaaccaa gtaaaattca attcaaatat cactatttct catacaggtg
     9121 gtcaattatc gagtgattcg ggtctcgtcc tagtgaaaga gctgatgaac atctttggtt
     9181 tttctgaact ggctaagcaa cacattcaca ttgaagacga acgagcgtat tttactcatg
     9241 acaacttatc catacttgag cagttcatta tgcaattaat tgctggttac tcagctgatt
     9301 ctgcagctaa tctcctgaga caagatcctg tgtttaaagc tgttttagat aggaaagaac
     9361 tcgcttctca atcttcactt tcccgatttt tagatcgact atctgaggag aatatccatg
     9421 aacttcaagc tttgaaccaa gaacttatcg ataaagcacg cctcatccgt aatgatacgg
     9481 aattaatcat tgatttagat tcgacccatt cagatacatt tggtcaccaa gaacaaacga
     9541 attataatac acactaccaa acctatggtt accatccatt ggtagctttt gacggattga
     9601 ctggtgactt cttaaaagct gaactacgtt caggaaatca atatacatca aaaggcgtaa
     9661 aggagtttct cacaccttta ttagagcact ataatcactc tctaccaaac actgacatct
     9721 tggttcgtgg agacagcggg ttcgctacac ctggtgtgta tgattcgtgt gaatcaaaaa
     9781 agagtcatta tgttattcga ctgaagaata atcgtagact aggtcaaata gctgagaaat
     9841 cagtacttta tggcgataat caaaagtggg aagaacgaga agttcagtac ttctcgacca
     9901 cttatcaagc acaatcctgg tcacaaagtc gtcgcgtgtg tatacgctca acacgtgaag
     9961 cgggcgaact actctttcga catgaattta tcgtgacgaa tctatcagaa aatgtttctc
    10021 ctgataccat cttttctatc tatgccaaac gtggcacaat ggagaacttc attaaagaag
    10081 cgaaagctgg cttttacttt gacaaaacag acagtcctcg ctttttggag aatcatgtcc
    10141 gaatgatgct cagcttgata gcttacaact tagtcaactt cttaagaacg attggctttg
    10201 aagaagtcca aaagggaatg accattcatt ctattcgatt gaagtttctg aaagttgctg
    10261 ggaaattagt ccaaacgggt agacgagtct atctcaaatt atctagttat catgtgtatc
    10321 agaatgaatt ctacagggtc tttgctcgcc tgaggcgagc cagtcaatgg atctaatcca
    10381 acaatctaac gattttttta ctgggaagtt atccagggag aagtatgctc aaaatgcctt
    10441 acacccaaaa tttattcctc aatatttttg aacagtgaat gtttgaagta actttttagt
    10501 caaaatcagt tgatagggat attagtgata catatttcaa taaaatgtgc caaagaatta
    10561 aagctatgaa ttattcaggg atagctttat gtatagagat ttttatgaag aatctataga
    10621 attgactcca acggaaccaa ataaatctca aatcactttg tcaaaggagc tagagagaaa
    10681 agtagagtct caagaactag ctataggaat tagtataacc aatgtgtcga catacaaaga
    10741 attatacgaa gctaaatcac aagataataa ggattttgta gaaaatatag ataaggaacc
    10801 aacaaataca gtaggggatt aacgtaaata agtgaagatt atattaacag actctttatt
    10861 tagttaagta aaaaatggtt tgttggaatt ttatgcttta tctgttctga gtaagactta
    10921 attttataga tagtaattat atgtaggaaa ttaaagatga gaagataata aaagcagcat
    10981 gatcaactat ttgtcattga ccatgctgtc tttttttatt ctatacacgg tttgtctcgt
    11041 aacattgtag tctttagcaa tcttagcaat cgcaacacca tttttaagat cttcaacgat
    11101 gcttttgtaa acaaggcgac gttggggatc ttttgcgtct gcactgtata atttgggccg
    11161 ccctttgtag acgccgtttg cttttgcgat cttaattcct tgtgcctggc gacgtttcga
    11221 ttcagtccgt tcttgttcag cgatcatggc caaaatttgg atgatcagat ccttaatgaa
    11281 tttatccagg agaggattgc caattgcttc agccatgatc ggtaaactag taatgatcag
    11341 cttcacattt ttcttcttca agtaattgac tgaagcgatg atctcgtcat aatttcttcc
    11401 aagtcgatca atagcttcca caataaaaat atcttgatct cggacgtaat ctaatgcttc
    11461 ttggaaaaca ggtcgatgag taatcgttgc gccagattgt ttctcgatga aaattctctc
    11521 tgcaccgaat tttttcattt cttcaatctg gcgttgttca ttttgatcga tcgatgagac
    11581 acgtatgtat gcaactctca aaacttttac ctactttctg caactattta aaatacaccc
    11641 taatcataca cgaggaagcc atatttttca atgttatacc agtgtctatt tagggtaaac
    11701 cttatataga caaaaactaa tgatggagga aatagtatga gaattttttg taagtgtcta
    11761 ctgataactt attctcaaat gttgtaagga ttttattcat ttgttaatat taaagaacgg
    11821 aactccaaaa aagtccgtac tctaatttgc agtctctcac tcttttagag tgagagtttt
    11881 tattagattt tcaaattaat tagtaaagtg atagaataaa ttgatcatac aaatcaaaag
    11941 aagaagcagg gtgatagcat acctatgctt ctttttttat gtatttagct atttcttctt
    12001 tacaatatcg aacatatgtt tgtataatgt gaaagaatgg agtgttattt atgatggatt
    12061 attcaaaaga gccagtaaat gattactttt taatcgatat gaaaagcttt tacgcaagtg
    12121 tcgaatgtat agaaagaaat ttagatccat taacaacaga acttgttgtt atgagtcgag
    12181 ctgataatac tggttcagga ttgatattag cttcttctcc tgaagcaaaa aagcggtatg
    12241 gtattacaaa tgtgagtaga ccacgtgact taccacaacc atttcctaaa acactacacg
    12301 ttgttccacc acgtatgaac ctatatatca agcgaaatat gcaggtaaat aatattttca
    12361 gaagatatgt ggctgatgaa gatctactga tttactcgat cgatgaatca atcttaaaag
    12421 tgacccgatc actgaatctt tttacgactg aaggaacacg aagtcaacgg agaaagaagc
    12481 tggctcaaat gatccaggag aatattaaag aagagctagg attgattgct acagtaggtg
    12541 tcggagataa tccccttttg gctaaactag ccttagacaa cgaagcaaag cataatgaag
    12601 gatttgttgc ggaatggacg tacgaaaacg ttcctgaaaa agtatggaat attcctgaaa
    12661 tgacggactt ttggggaatt ggctctcgaa tgaaaaaaag actcaatcag atggggatta
    12721 tgagcattag agatcttgct aactggaatc cttatacgat taagaataga ctaggtgtga
    12781 ttggcttaca gctgtacttc catgctaatg ggatcgatcg aacagatata gcaatcccac
    12841 cagaaccgac aaaggaaaaa tcatatggaa attcacaagt gttaccacga gattatacta
    12901 gaagaaatga aatcgagctg gtggtaaaag aaatggcgga acaagtagcg atacgcatta
    12961 ggcagcataa ctgtaaaaca ggttgtgtcc atttacacat tggcacgtcg atcttagaaa
    13021 cgagaccagg gttttcacac cagatgaaga tccctatcac agataataca aaggaattgc
    13081 agaattattg tcttttcttg tttgataagt attatgaagg acaagaagta aggcatgttg
    13141 gaataaccta tagcaagctt gtgtacaccg attcgcttca gctggattta tttagtgatc
    13201 cacaaaagca aattgacgaa gaaaatttag ataaaattat tgacaagatt cggcaaaaat
    13261 atggttttac gtcgattgta catgcttctt caatgttaga aggcgctaga agcattacta
    13321 gaagcacact tgttggtggt catgcgggcg gaaatggggg aattaaaaat gattgattac
    13381 aatgatcgtg gacgtttaaa gtgggcaggg ttttatttat ctgatcatac tgaagaaatt
    13441 gatgccgaca atgaacaacg aaccagtcaa aatttagcaa aagaacaaat gacgactgaa
    13501 gagattgcgg aagtattgaa cgctgcagtc ataaaaaata gatcagtatc tattcaaaaa
    13561 gaagaacgaa acgctgaagg atactatcca gaagatatca ttggcaagat cttaggtagt
    13621 gatgagctgg ggatctacgt tggaaaagac aaaattcact acgacgaaat acgtcatatc
    13681 gaattttacc aggataataa atggagtcga ttagaatgaa cattatccag caatatgagc
    13741 taaagtatat aacctttgat cagctatcag aagagatttg gggttatggc caacgtttga
    13801 taaatgaggt tggtgttgag cgcttctctt tctatgtaga agctgcagca ggttatcata
    13861 attttaggtt ttatatcttc ccgttatata tataaggtat tttacggatt ctatagagtt
    13921 atctctatga atcctttttt gtttttacaa ataggagtag atactagaat aatgcgtgtg
    13981 ttaaactatt attgcaaacg caataataaa agaaagtagg cttacgcacc atgtctatca
    14041 atacatttgt ttactcgcac ccgatcaatg tttacattat caagaattta ggaatcactg
    14101 tagaacaatt ttgtgagtta tatgcctacc cacaaggaac ggttgcaagc tggataaccc
    14161 gacaacgtag aataaaatca ttacctgctt cattcgttta tgatttaagc ctggcctcta
    14221 gtttaaacat gtctgatgtt tatgaaaagc tcctgtcttt agaaaaagaa tatgattcct
    14281 tcaagattaa acatgataaa aaaataaaaa aacatatata atatcaatca caattgtata
    14341 atattacgat atcttaatat catgatatcg taatattgtt tttttctaag aaaatgcact
    14401 ataagaaggg aattattagt aacaatatag acagtttagt aatgtttaaa ttattctagt
    14461 tgctgctcgc aaaacatatt tcttatcatt aataaaaaat tttaaagtaa taaaaagtga
    14521 ttattttaat ttcgaataac atatgaataa tctttatatc cgaaccgata tatatcttta
    14581 aaacaaaata atcacacaat attacaatat aatgcatata cgatattgca atatcacaat
    14641 attatgatat aattatatta taatataaga tgaatggggg atattttaat ggcaagaata
    14701 ttgtcagtag ccaatcaaaa aggtggagtt tctaaaacta cgactagcgt taatttagca
    14761 gcatgtttga aatttgttta cggtaaaaat gtacttttag tggacattga tcctcaggga
    14821 aatgctacag ataatgtagg tttcgatata gatggaacaa accaacctac aatttatgaa
    14881 gtattaaaag gggaggctga cattacagat gctattctgg actataaagg aattgatgtt
    14941 ttgccagccg acatagccct ttcttctgca gagagggaat ttactcaagt aggaagtgaa
    15001 cacaggctta aaagagtact tcaaccaatc aaggacaact atgattatat tataattgat
    15061 tgtccaccaa gtttaggaat gcttacagtc aacgcattta ctgtttctga tgaaattatc
    15121 attccagttg aagctgcgta tttctcatta aaaggactaa taaagttaag tgaaactatt
    15181 gaaacggtaa aagaatatac gaacgacaag cttgaagtac gaggagttct atttactaag
    15241 tataataagc gttataacat ttctaaagaa atgacgtctg cagcaaccga aatttctaga
    15301 gtcattggtg caaaaatttt caaaacttat attcgtagga caataaccgt tgacgaagcg
    15361 caagctgctg gatcagatct aatcaatttt aataaaccct caacagctga agatgactat
    15421 aaagcattta cagaagaata tttaaaagaa gttggtgatt ttgatggcag aagataatcg
    15481 cagtcaagct gcagtaagta gattactagg aaataaaaat aaaaagaatt ttaaatcaaa
    15541 agaagtagaa gaaatcgaat taaccaagaa aaatataagt aaagtcataa aagatcaagg
    15601 aagtagtgta agaacagcag atagcattcg tataaatcca attctaatgt cagcactcaa
    15661 atattggacg actattgctg aatcagacaa aagtaaacca gacgttatag aagatgcgct
    15721 attaaagtcc atacctgaag aatacttgat tgaaggatat aaactagcaa agaaacaaaa
    15781 taaaatttaa tttacattca atatcacgat atcataatat cgtgatattt tttttataaa
    15841 aatcagtagt atcaaagctg ataagtcgct tatcttcata ttgtaatatt acgatatcgt
    15901 gatataatat tattgtaata tcgtgatata gttactatga gcttaaacct tgaaatagag
    15961 cggtttgctt taatttattt tttaaggtaa actaaaaaaa gataaaaaaa gactactgct
    16021 ttaacaaagt ttggcgactt atcagcagta gaaaaatata tagtggatag atatatttgt
    16081 ttaattcatt gtaacatagt tttgaacaaa acgctatcct acagaaagag gattggct
//
