LOCUS       CP063572               15826 bp    DNA     circular BCT 04-APR-2022
DEFINITION  Enterococcus faecium strain BMT-1-1-11 plasmid pIN-1-11_04, complete
            sequence.
ACCESSION   CP063572
VERSION     CP063572.1
DBLINK      BioProject: PRJNA669626
            BioSample: SAMN16483162
KEYWORDS    .
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15826)
  AUTHORS   Both,A., Kruse,F., Mirwald,N., Franke,G., Christner,M., Huang,J.,
            Hansen,J.L., Kroger,N., Berneking,L., Lellek,H., Aepfelbacher,M. and
            Rohde,H.
  TITLE     Population dynamics in colonizing vancomycin-resistant Enterococcus
            faecium isolated from immunosuppressed patients
  JOURNAL   J Glob Antimicrob Resist 28, 267-273 (2022)
   PUBMED   35134550
REFERENCE   2  (bases 1 to 15826)
  AUTHORS   Both,A., Kruse,F., Christner,M., Huang,J., Mirwald,N., Franke,G. and
            Rohde,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute of Medical Microbiology, Virology
            and Hygiene, University Medical Center Hamburg-Eppendorf,
            Martinistr. 52, Hamburg, Hamburg 20246, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Trycycler v. v0.3.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 469.7x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 10/27/2020 16:31:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.13
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,221
            CDSs (total)                      :: 3,129
            Genes (coding)                    :: 3,023
            CDSs (with protein)               :: 3,023
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 25 of 106
            Pseudo Genes (incomplete)         :: 69 of 106
            Pseudo Genes (internal stop)      :: 24 of 106
            Pseudo Genes (multiple problems)  :: 11 of 106
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..15826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="BMT-1-1-11"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pIN-1-11_04"
                     /geo_loc_name="Germany: Hamburg"
                     /lat_lon="53.33 N 10.1 E"
                     /collection_date="2014-07-08"
                     /collected_by="Institute of Medical Microbiology, Virology
                     and Hygiene, University Medical Center Hamburg-Eppendorf"
     gene            join(15120..15826,1..619)
                     /locus_tag="IQN14_15970"
     CDS             join(15120..15826,1..619)
                     /locus_tag="IQN14_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UOE06154.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            612..962
                     /locus_tag="IQN14_15975"
     CDS             612..962
                     /locus_tag="IQN14_15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06155.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            959..1138
                     /locus_tag="IQN14_15980"
     CDS             959..1138
                     /locus_tag="IQN14_15980"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06156.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            1274..1564
                     /locus_tag="IQN14_15985"
     CDS             1274..1564
                     /locus_tag="IQN14_15985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="UOE06157.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="type III secretion system protein PrgN"
     gene            1917..2720
                     /locus_tag="IQN14_15990"
     CDS             1917..2720
                     /locus_tag="IQN14_15990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UOE06158.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDI
                     DPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFT
                     QVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLI
                     KLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRR
                     TITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="ParA family protein"
     gene            2707..3033
                     /locus_tag="IQN14_15995"
     CDS             2707..3033
                     /locus_tag="IQN14_15995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06159.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     gene            3382..4422
                     /locus_tag="IQN14_16000"
     CDS             3382..4422
                     /locus_tag="IQN14_16000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="UOE06160.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(5039..5719)
                     /locus_tag="IQN14_16005"
     CDS             complement(5039..5719)
                     /locus_tag="IQN14_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOE06161.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            5794..5982
                     /locus_tag="IQN14_16010"
                     /pseudo=""
     CDS             5794..5982
                     /locus_tag="IQN14_16010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /name="topoisomerase C-terminal repeat-containing protein"
     gene            6116..6357
                     /locus_tag="IQN14_16015"
                     /pseudo=""
     CDS             6116..6357
                     /locus_tag="IQN14_16015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /name="peptide-binding protein"
     gene            6406..6489
                     /locus_tag="IQN14_16020"
     CDS             6406..6489
                     /locus_tag="IQN14_16020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="UOE06163.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYTDK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            6614..7351
                     /gene="erm(B)"
                     /locus_tag="IQN14_16025"
     ARG             6615..7348
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7521..7781
                     /locus_tag="IQN14_16030"
                     /pseudo=""
     CDS             7521..7781
                     /locus_tag="IQN14_16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            complement(7938..9233)
                     /locus_tag="IQN14_16035"
     CDS             complement(7938..9233)
                     /locus_tag="IQN14_16035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="UOE06147.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFL
                     VTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
                     /name="ISL3-like element ISEfa11 family transposase"
     gene            9466..9765
                     /locus_tag="IQN14_16040"
                     /pseudo=""
     CDS             9466..9765
                     /locus_tag="IQN14_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(9816..10496)
                     /locus_tag="IQN14_16045"
     CDS             complement(9816..10496)
                     /locus_tag="IQN14_16045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOE06148.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            10523..11218
                     /locus_tag="IQN14_16050"
     CDS             10523..11218
                     /locus_tag="IQN14_16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06164.1"
                     /translation="MILPYLIVDLKLCNRTEHLNEVIRRIQKDFSCMEEMKYFIQRVEE
                     QLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENF
                     VSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIV
                     LMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPY
                     QRFERKKRQ"
                     /name="hypothetical protein"
     gene            11599..11778
                     /locus_tag="IQN14_16055"
     CDS             11599..11778
                     /locus_tag="IQN14_16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06149.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            11909..12178
                     /locus_tag="IQN14_16060"
     CDS             11909..12178
                     /locus_tag="IQN14_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="UOE06150.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            12171..12428
                     /locus_tag="IQN14_16065"
     CDS             12171..12428
                     /locus_tag="IQN14_16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="UOE06151.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            12887..13891
                     /locus_tag="IQN14_16070"
     CDS             12887..13891
                     /locus_tag="IQN14_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE06152.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(14056..14670)
                     /locus_tag="IQN14_16075"
     CDS             complement(14056..14670)
                     /locus_tag="IQN14_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UOE06153.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     ARG             6615..7351
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          3383..4422
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gattaagaat agactaggtg tgattggctt acagctgtac ttccatgcta atgggatcga
       61 tcgaacagat atagcaatcc caccagaacc gacaaaggaa aaatcatatg gaaattcaca
      121 agtgttacca cgagattata ctagaagaaa tgaaatcgag ctggtggtaa aagaaatggc
      181 ggaacaagta gcgatacgca ttaggcagca taactgtaaa acaggttgtg tccatttaca
      241 cattggcacg tcgatcttag aaacgagacc agggttttca caccagatga agatccctat
      301 cacagataat acaaaggaat tgcagaatta ttgtcttttc ttgtttgata agtattatga
      361 aggacaagaa gtaaggcatg ttggaataac ctatagcaag cttgtgtaca ccgattcgct
      421 tcagctggat ttatttagtg atccacaaaa gcaaattgac gaagaaaatt tagataaaat
      481 tattgacaag attcggcaaa aatatggttt tacgtcgatt gtacatgctt cttcaatgtt
      541 agaaggcgct agaagcatta ctagaagcac acttgttggt ggtcatgcgg gcggaaatgg
      601 gggaattaaa aatgattgat tacaatgatc gtggacgttt aaagtgggca gggttttatt
      661 tatctgatca tactgaagaa attgatgccg acaatgaaca acgaaccagt caaaatttag
      721 caaaagaaca aatgacgact gaagagattg cggaagtatt gaacgctgca gtcataaaaa
      781 atagatcagt atctattcaa aaagaagaac gaaacgctga aggatactat ccagaagata
      841 tcattggcaa gatcttaggt agtgatgagc tggggatcta cgttggaaaa gacaaaattc
      901 actacgacga aatacgtcat atcgaatttt accaggataa taaatggagt cgattagaat
      961 gaacattatc cagcaatatg agctaaagta tataaccttt gatcagctat cagaagagat
     1021 ttggggttat ggccaacgtt tgataaatga ggttggtgtt gagcgcttct ctttctatgt
     1081 agaagctgca gcaggttatc ataattttag gttttatatc ttcccgttat atatataagg
     1141 tattttacgg attctataga gttatctcta tgaatccttt tttgttttta caaataggag
     1201 tagatactag aataatgcgt gtgttaaact attattgcaa acgcaataat aaaagaaagt
     1261 aggcttacgc accatgtcta tcaatacatt tgtttactcg cacccgatca atgtttacat
     1321 tatcaagaat ttaggaatca ctgtagaaca attttgtgag ttatatgcct acccacaagg
     1381 aacggttgca agctggataa cccgacaacg tagaataaaa tcattacctg cttcattcgt
     1441 ttatgattta agcctggcct ctagtttaaa catgtctgat gtttatgaaa agctcctgtc
     1501 tttagaaaaa gaatatgatt ccttcaagat taaacatgat aaaaaaataa aaaaacatat
     1561 ataatatcaa tcacaattgt ataatattac gatatcttaa tatcatgata tcgtaatatt
     1621 gtttttttct aagaaaatgc actataagaa gggaattatt agtaacaata tagacagttt
     1681 agtaatgttt aaattattct agttgctgct cgcaaaacat atttcttatc attaataaaa
     1741 aattttaaag taataaaaag tgattatttt aatttcgaat aacatatgaa taatctttat
     1801 atccgaaccg atatatatct ttaaaacaaa ataatcacac aatattacaa tataatgcat
     1861 atacgatatt gcaatatcac aatattatga tataattata ttataatata agatgaatgg
     1921 gggatatttt aatggcaaga atattgtcag tagccaatca aaaaggtgga gtttctaaaa
     1981 ctacgactag cgttaattta gcagcatgtt tgaaatttgt ttacggtaaa aatgtacttt
     2041 tagtggacat tgatcctcag ggaaatgcta cagataatgt aggtttcgat atagatggaa
     2101 caaaccaacc tacaatttat gaagtattaa aaggggaggc tgacattaca gatgctattc
     2161 tggactataa aggaattgat gttttgccag ccgacatagc cctttcttct gcagagaggg
     2221 aatttactca agtaggaagt gaacacaggc ttaaaagagt acttcaacca atcaaggaca
     2281 actatgatta tattataatt gattgtccac caagtttagg aatgcttaca gtcaacgcat
     2341 ttactgtttc tgatgaaatt atcattccag ttgaagctgc gtatttctca ttaaaaggac
     2401 taataaagtt aagtgaaact attgaaacgg taaaagaata tacgaacgac aagcttgaag
     2461 tacgaggagt tctatttact aagtataata agcgttataa catttctaaa gaaatgacgt
     2521 ctgcagcaac cgaaatttct agagtcattg gtgcaaaaat tttcaaaact tatattcgta
     2581 ggacaataac cgttgacgaa gcgcaagctg ctggatcaga tctaatcaat tttaataaac
     2641 cctcaacagc tgaagatgac tataaagcat ttacagaaga atatttaaaa gaagttggtg
     2701 attttgatgg cagaagataa tcgcagtcaa gctgcagtaa gtagattact aggaaataaa
     2761 aataaaaaga attttaaatc aaaagaagta gaagaaatcg aattaaccaa gaaaaatata
     2821 agtaaagtca taaaagatca aggaagtagt gtaagaacag cagatagcat tcgtataaat
     2881 ccaattctaa tgtcagcact caaatattgg acgactattg ctgaatcaga caaaagtaaa
     2941 ccagacgtta tagaagatgc gctattaaag tccatacctg aagaatactt gattgaagga
     3001 tataaactag caaagaaaca aaataaaatt taatttacat tcaatatcac gatatcataa
     3061 tatcgtgata ttttttttat aaaaatcagt agtatcaaag ctgataagtc gcttatcttc
     3121 atattgtaat attacgatat cgtgatataa tattattgta atatcgtgat atagttacta
     3181 tgagcttaaa ccttgaaata gagcggtttg ctttaattta ttttttaagg taaactaaaa
     3241 aaagataaaa aaagactact gctttaacaa agtttggcga cttatcagca gtagaaaaat
     3301 atatagtgga tagatatatt tgtttaattc attgtaacat agttttgaac aaaacgctat
     3361 cctacagaaa gaggattggc tatgaatgat tttaattatt acaaatcaaa agaaatttat
     3421 cgtgaaaaat attatcaaat gcctaaggta ttttttacta acgaaaaata catggatcta
     3481 tcaaatgatg caaaaattgc ttatatgcta cttaaagatc gatttgatta ttcagtcaaa
     3541 aataactggg tagattctga tgataatata tttttcatat tcacagttga agaattaatg
     3601 aaattgttac aatgccgcga aggtaaagta tctaaaatca aaaaggaatt agaaaaagca
     3661 ggtcttctga aacagaagag aggaagagta aataaacgtg acggtaagat tgaatccatg
     3721 cctaatttat tgtacttagg caagccagaa gtaacgaatc aagacgtctt taaaatcatg
     3781 gaagaggaag acaatactga taccaccgta attgcgaaaa tcgcaaatac ggcaaaaccg
     3841 cgagaaatca atgataccac cgtaattgcg aaaatcgcaa atacggcaaa atccagtcat
     3901 atcaaggact caaccgtaat tgcgaaaatc gcagacaatc tattctattc taattctata
     3961 gacactaata gacacataat agacactgaa actgatcagt tacaaaatca agttttacta
     4021 gataacttcg tcgacatcat gaaagaggac agtataaata catttgtacc agaaaatgta
     4081 ttaaacttga taaaaacatt ttctagtact tacgaagacg ctcaaaaaac cgtccaaact
     4141 attcataatg caaagaaaaa agctgaagaa ttagagcaaa cagttgttgt ttatgaagaa
     4201 ctggaatctt atggaattga tgctgacaaa ggattatata tgactttgct gaaagcttat
     4261 caaaaacaaa aaactgaaaa agtaaacaat ttgcagaatc taattttcgt ttatgtaaaa
     4321 aattggtttg tcgaaaaagc tattgcggca aagcttgcaa acgaacaaag agaaacattt
     4381 aacgaattac caacagttag tacggaaaat tggctagagt agttgataaa aagcgatcac
     4441 tataaaaatg atcaatttta aattagaact tttttatgat tttaatttta ttacaaatgt
     4501 tacaaataaa tagctattat tccggagttt ttagattaaa agtttatgaa aacaatcaca
     4561 aacgtaggtt ttaaagtcat aatcgttaga tattttagtt atttttcatt caaaaaaata
     4621 gggaactagt gtttgcgtat gtgctttttt gagttataat aattcatgaa gagaggtaat
     4681 tcacttattt ccccaagctg aaaagcctga tattacttct tttcaggcag tgctgctaat
     4741 attcaattac acttttttgt atatttttag ttgttttaaa tttaattgtc tgatatgctt
     4801 gtgatgaatt gattttcgtt ctgcactttt ggacgataaa ttgtgataat tgaaaataca
     4861 aaaaaaagaa aggcccctgt aaggctcggg agactggtaa tctccgtcag tgtcctacag
     4921 gaaagcatta agatgacgcc ttaatgccgt gcccttcagt gttacggtat tacccgcaac
     4981 ggacggttct gttgcaaagt tttaaataaa gaataaaatc ccttacggta tctatgattt
     5041 aagctgggat tcccaataat accttgattt cagtacagac cgaaaacccg aagagagtgc
     5101 cttcttttcg ggttttctta tataatcctc gaatggcttc catgccttta atcgtggtag
     5161 aggcagtgcg taaacttcga tagaatttat tgcgtctctt tactggacga tggtcttgtt
     5221 caatcaaatt attcaggtat ttaatggtac gatgttctgt cccttgataa aagccgtatt
     5281 cttttagttt cttaaaggca cttgtaatag agggggcttt atctgtgact acaaccttcg
     5341 gttcatcaaa ctgcttcact aaccgcttaa gaaaagcata ggctgcttgt gtgtcccgtt
     5401 ttttacgtaa ccaaatatcc aaggttaaac catctgcatc gatggctcga tacaaataat
     5461 gccattttcc tttaattttg atgtacgttt catccatttt ccatgaataa aaggattttt
     5521 tatttttctt tttccaaatt tgatagagta gtttgccata ttcttgcacc caacgataaa
     5581 tcgtcgtatg agaaacgtta atgccacgat catataagat ttcttgaact tcacgatagc
     5641 taaggttata acgaagatag tagcccacgg ctacaataat cacatcctgc tgaaattgct
     5701 ttcctttaaa atgattcatc gtcattcctc ctgctatctt tttctattat tctaccttat
     5761 ttgatagtag atttaaaact ttgcaacaga acccctgaat gtaagtttac tttagctgaa
     5821 cattttagaa agaaaaaact aaccaaaacg aatgtaaaag aattactgga gggaaaagaa
     5881 accctggtaa aaggaatcaa aaacaaagag aaaaagccct acaatgccgt tgtaaaaatt
     5941 ggggaaaagg gatatattga ttttatatct ttctcaaaat aaacataaaa gccctttaaa
     6001 gagggctttt atatattaat cacaaatcac ttatcacaaa tcacttatca caaatcacaa
     6061 gtgatttgtg attgttgatg ataaaataag aataagaaga aatagaaaga agtgagtgat
     6121 tgtgggaaat ttaggcgcac aaaaagaaaa acgaaatgat acaccaatca gtgcaaaaaa
     6181 agatataatg ggagataaga cggttcgtgt tcgtgctgac ttgcaccata tcataaaaat
     6241 cgaaacagca aagaatggcg gaaacgtaaa agaagttatg gaaataagac ttagaagcaa
     6301 acttaagagt gtgttgatag tgcagtatct taaaattttg tgtataatag gaattgaagt
     6361 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     6421 atgcgtaatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacaca
     6481 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     6541 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt atttacagat gtaatcactt
     6601 caggagtgat tacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     6661 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     6721 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     6781 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaacattcg
     6841 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     6901 aattgttggg agtattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     6961 aagccatgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     7021 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     7081 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     7141 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     7201 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     7261 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     7321 tagttatcta ttatttaacg ggaggaaata attctatgag tcgctttttt aaatttggaa
     7381 agttacacgt tactaaaggg aatggagata aattattaga tatactactg acagcttcca
     7441 agaagctaaa gaggtcccta gcgcctacgg ggaatttgta tcgataaggg gtacaaattc
     7501 ccactaagcg ctcgggaccc cttgtaggaa aatgtcctaa gtgtggcaac aatattgtat
     7561 taaaaaaatc gttttatggt tgttcaaatt atcctgaatg taagtttact ttagctgaac
     7621 attttagaaa gaaaaaacta accaaaacga atgtaaaaga attactggag ggaaaagaaa
     7681 ccctggtaaa aggaatcaaa aacaaagaga aaaagcccta caatgccgtt gtaaaaattg
     7741 gggaaaaggg atatattgat tttatctctt tttcaaaata aacatggggc tgacccaaaa
     7801 gtagctccta tatgaaaaat agaggtcttt ccatttagat agtagtggaa agaccggctc
     7861 tttgtcaata aggactgatg agttgtgcaa aatcaaatct gagtcagaat gaaccacatt
     7921 ctggctcaga ttttttgtta tcttacattg attaattgat tgatcaaaaa gattctaatt
     7981 ctcatgttct caaatgattt aaatccgtag gatactcgtt tcattgtctt tatgtgggta
     8041 ttcttcgctt ctatttttcc attggaataa ggatagatca ttgcgttggt gatgccttct
     8101 tcataggtca gaaggttttg aagcttttcc cgaaagctgt catctaacgt ttcgggaagt
     8161 tctgccaata aggagaaaaa taagtcaggg tctttgtctc gaaaggcttc aactaattca
     8221 tgaaaaaagg gatacgcctc ctttaggggc ggagaaaact caagcaatcg atcaatcatc
     8281 attgcttcag taagaaatgg gtattttggt gctcggaaac ttttccatgt tttgtattca
     8341 taatggttga tgtttgcacg attttttagc aaaaagcgcc agttcttttt cagtttttct
     8401 gcctggcttt tctgtccggc tttacgaagt tcattcattt cacggatacg caactcattg
     8461 aacgcttgat tcatgtgttt gacaatatga aaccgatcaa tcacgacttt cgcatttggc
     8521 agaacacgtt tggtgagctg gaagtaggcg gcgttcatgt ctgtcaccaa gaattctact
     8581 tcttctggat tggtacaacc taagaaatag cttgttaatc gaggtaattt acgcgtaggc
     8641 aaaacatcta ttaattttcc tgtttcgcca tccgcgcaaa taaagctcat cttatcttct
     8701 atggaagcat gcgaacgaaa ttcgtcaacc atcaatactc tggggaggat cttcttagat
     8761 tgctttggta aatagctttt aaactctttc aatgtacgaa taacggtggt caaagatacc
     8821 tgacagcttt tcgcaataaa agataaagat actttttcag tcagtaaaga agcaatttta
     8881 tatctaacat gatttgcgat tgaatgtctg ggttggacaa aataactttg agccgtccaa
     8941 tgggtgcgac agtttttaca ggtatagcgt tgctttttta ggcgcataac caaaggcata
     9001 tgattgtatt gttcaaaacg gacaatcgtt tccttttttc catttttcac tataattgct
     9061 ttcccgtttc catctaccac agtagaacca caacttctac aagcacgagg agtaggcgag
     9121 agaacagcat cgacgaccaa cgtctttttc ttctgaaggg tctcgtaaga gacctctgta
     9181 atcatcaaat ctttctctgt tattctcagc atttttttga tagaatcatt catatagcgt
     9241 atcgtcctct cagttgttta ttttgtggtg atttaatcat actagagaac gatatgtttt
     9301 ttaataccta aaatgaaaat ggggctgaag aatcaattct gattcatcag tcccataaat
     9361 tatagagccg aaagacctct atttatcttt tgaaagtgaa tacaaaaata aagcacactc
     9421 tgctataata taggtgatta atccatttga gagaggtgct ttatcatgta tcaaaattat
     9481 accataaacc aactttgttt gcctatagat cttgaaatta aattagaaga aaatgatttt
     9541 gctcatgcca ttgtgcagtt tgttgactct attcccgatg aagtctttct tccttattat
     9601 caatctatgg gtagacccca atatcatcct cgtatgctac tttccattat tctttgtgcc
     9661 tatattcaag gggtttattc gggccgccaa atacaaaata tgctgataga tagtattcgg
     9721 atgcgctact tatctcaaga gcaattccct aactttcgta cggttctgtt gcaaagtttt
     9781 aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc caataatacc
     9841 ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt tttcttatat
     9901 aatcctcgaa tggcttccat gcctttaatc gtggtagagg cagtgcgtaa acttcgatag
     9961 aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt caggtattta
    10021 atggtacgat gttctgtccc ttgataaaag ccgtattctt ttagtttctt aaaggcactt
    10081 gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg cttcactaac
    10141 cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca aatatccaag
    10201 gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt aattttgatg
    10261 tacgtttcat ccattttcca tgaataaaag gattttttat ttttcttttt ccaaatttga
    10321 tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg
    10381 ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg aagatagtag
    10441 cccacggcta caataatcac atcctgctga aattgctttc ctttaaaatg attcatcgtc
    10501 attcctcctg ctatcttttt ctattattct accttatttg atagtagatt taaaactttg
    10561 caacagaacc gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10621 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10681 gagtcaaacg aaggtcacag tcagccataa tcgtttagac gtgtataaac gtcgtcctga
    10741 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10801 ttacctagaa aggagtgagc tggtcgaaaa ctttgtcagc tacacgattt gcaggaaaca
    10861 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10921 aatggaagag ctaaacagca aagatgcgac gatagacgat tattaccttg tatttactag
    10981 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    11041 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    11101 cacgacttta actgattttt tagacaccta tacttacgac gatacagaag aaatccaaaa
    11161 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11221 atttataccg aaaagtgaga atgtgtgaaa taaggacaaa aaacctagta actaagggaa
    11281 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11341 gcgggcaaca cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11401 ctattgttag tcctatttgt tggcgaaata cttatgcgcc atgctgcagc tgtgcattta
    11461 aacttcgtag tatttttggc aatactggta ttttgtttga tcttttggcg ctttgtatta
    11521 gcccttgtga gtctactatt caagatgatt gcagccatat ttttcatagg gttatttcga
    11581 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgttacgttg
    11641 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggcaa aagtgaatcc
    11701 aggattatgt gtattgcgtt agatttattg attgcccaag aaaaagcagg atttgaggta
    11761 ccagcactca aaaagtgacg tcacttttta tcctaaaaac taaaagtgat agcactttta
    11821 attataagaa gttagaatat taatcatttg cttaattgta caatataatg tacaattgtt
    11881 ttatagaaat aaataagggg tgaaaggaat ggaagcagta gcttattcaa atttccgcca
    11941 aaatttacgt agttatatga aacaagttaa tgaggatgct gaaacactta ttgtaacaag
    12001 taaagatgta gaagatacag ttgttgtatt atcaaaaaga gattatgatt ctatgcaaga
    12061 aacgttgaga acactttcta ataattacgt catggaaaaa attcgtcgag gagatgaaca
    12121 attctccaaa ggtgcattta aaacacatga cttaatcgag gttgaatctg atgattaagg
    12181 cttggtctga tgatgcttgg gatgattatc tttattggca tgagcaagga aacaaaagca
    12241 atataaaaaa gattaacaag ttaataaaag atatcgatcg ttcccccttt gctggattag
    12301 gaaaacctga gccattaaag catgatttat ctggaaaatg gtccagaaga attacagatg
    12361 aacatagact gatatataga gttgaaaatg aaacgatatt tatttattct gcaaaagatc
    12421 actattaacc aatcggaagt aaggaaaggg tcagaaactt aaaagttttt gatccttatt
    12481 ttatttaccc tagtcattta aaaagctaat atagcttagt gttgattgtt attaatgaat
    12541 gtgtttgtta cgcgtattac ggatataagg ttagtaaaat catttctaaa gttgaggaaa
    12601 agtaaatata aatggcttaa atttcaacaa tttgaagttg aatagatatg ttataatact
    12661 attgtagtgt gggatgttag ttactaaagg atgacgctta tatatatgac tgaatagaat
    12721 aagcaatagg tttaataatc tattttaaat tttttgtact agttttagtt aattagcaaa
    12781 aacaacaaaa ataaacttct catagaattt agctaaaaat taatgattta tttacatatt
    12841 aaatttggat acagttaagt aatttttata tattggagga gaagtaatgg aatataaatt
    12901 taacttgaat ttgaaagaag tactccccac tcagggaaca ataaacataa atggtcaaga
    12961 taatgatgac gatatagtaa taaaaaaaat agaatttatt gattctgata taaatgtttt
    13021 tttttattct aaagaaaaat tagctgattt tagcaatatt gctgaaatga ttgaacgttt
    13081 aaaagatttt atgatcagtg tttgggatgt agcgatgctt gctgacgaat caaattatac
    13141 ttcgagcata tacagattag aagatagtaa ttggatagaa atttcattag agttaaagac
    13201 acttcctaat tccgttaact atataattag agatataact tctgaagctc aacaattagt
    13261 taattacatg catggacacg aaagtatccc cttttctctt atactcctta aaagaagtaa
    13321 aaatatatca aatactagag ataggtttat ttcgataatt acagcctgtg aaataggggt
    13381 aaaggaattt tatcaacaag agaaacctga tttaactcta atatttgaga atttacaatc
    13441 tccccctgta gacaaattat tagggagcat gtttaaaggg tactttaata ttgagtttcc
    13501 gaaagaaata agaaaggaaa ttaaaaattt catagaaaaa cgtaataaat tggttcattc
    13561 tcctcaagga agtaaaccaa ctatagaaga atgttttgaa tgttatatgg cagtgctaaa
    13621 aacatttaat tttttttata aaattaatga tagctttatg tatagagatt tttatgaaga
    13681 atctatagaa ttgactccaa cggaaccaaa taaatctcaa atcactttgt caaaggagct
    13741 agagagaaaa gtagagtctc aagaactagc tataggaatt agtataacca atgtgtcgac
    13801 atacaaagaa ttatacgaag ctaaatcaca agataataag gattttgtag aaaatataga
    13861 taaggaacca acaaatacag taggggatta acgtaaataa gtgaagatta tattaacaga
    13921 ctctttattt agttaagtaa aaaatggttt gttggaattt tatgctttat ctgttctgag
    13981 taagacttaa ttttatagat agtaattata tgtaggaaat taaagatgag aagataataa
    14041 aagcagcatg atcaactatt tgtcattgac catgctgtct ttttttattc tatacacggt
    14101 ttgtctcgta acattgtagt ctttagcaat cttagcaatc gcaacaccat ttttaagatc
    14161 ttcaacgatg cttttgtaaa caaggcgacg ttggggatct tttgcgtctg cactgtataa
    14221 tttgggccgc cctttgtaga cgccgtttgc ttttgcgatc ttaattcctt gtgcctggcg
    14281 acgtttcgat tcagtccgtt cttgttcagc gatcatggcc aaaatttgga tgatcagatc
    14341 cttaatgaat ttatccagga gaggattgcc aattgcttca gccatgatcg gtaaactagt
    14401 aatgatcagc ttcacatttt tcttcttcaa gtaattgact gaagcgatga tctcgtcata
    14461 atttcttcca agtcgatcaa tagcttccac aataaaaata tcttgatctc ggacgtaatc
    14521 taatgcttct tggaaaacag gtcgatgagt aatcgttgcg ccagattgtt tctcgatgaa
    14581 aattctctct gcaccgaatt ttttcatttc ttcaatctgg cgttgttcat tttgatcgat
    14641 cgatgagaca cgtatgtatg caactctcaa aacttttacc tactttctgc aactatttaa
    14701 aatacaccct aatcatacac gaggaagcca tatttttcaa tgttatacca gtgtctattt
    14761 agggtaaacc ttatatagac aaaaactaat gatggaggaa atagtatgag aattttttgt
    14821 aagtgtctac tgataactta ttctcaaatg ttgtaaggat tttattcatt tgttaatatt
    14881 aaagaacgga actccaaaaa agtccgtact ctaatttgca gtctctcact cttttagagt
    14941 gagagttttt attagatttt caaattaatt agtaaagtga tagaataaat tgatcataca
    15001 aatcaaaaga agaagcaggg tgatagcata cctatgcttc tttttttatg tatttagcta
    15061 tttcttcttt acaatatcga acatatgttt gtataatgtg aaagaatgga gtgttattta
    15121 tgatggatta ttcaaaagag ccagtaaatg attacttttt aatcgatatg aaaagctttt
    15181 acgcaagtgt cgaatgtata gaaagaaatt tagatccatt aacaacagaa cttgttgtta
    15241 tgagtcgagc tgataatact ggttcaggat tgatattagc ttcttctcct gaagcaaaaa
    15301 agcggtatgg tattacaaat gtgagtagac cacgtgactt accacaacca tttcctaaaa
    15361 cactacacgt tgttccacca cgtatgaacc tatatatcaa gcgaaatatg caggtaaata
    15421 atattttcag aagatatgtg gctgatgaag atctactgat ttactcgatc gatgaatcaa
    15481 tcttaaaagt gacccgatca ctgaatcttt ttacgactga aggaacacga agtcaacgga
    15541 gaaagaagct ggctcaaatg atccaggaga atattaaaga agagctagga ttgattgcta
    15601 cagtaggtgt cggagataat ccccttttgg ctaaactagc cttagacaac gaagcaaagc
    15661 ataatgaagg atttgttgcg gaatggacgt acgaaaacgt tcctgaaaaa gtatggaata
    15721 ttcctgaaat gacggacttt tggggaattg gctctcgaat gaaaaaaaga ctcaatcaga
    15781 tggggattat gagcattaga gatcttgcta actggaatcc ttatac
//
